Compounds > tylophorine
Page last updated: 2024-08-26

tylophorine and 1,7-phenanthroline

tylophorine has been researched along with 1,7-phenanthroline in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's9 (69.23)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Chuang, TH; Lee, SJ; Wu, PL; Yang, CW1
Fürstner, A; Kennedy, JW1
Bastow, KF; Lee, KH; Lin, JC; Liu, YN; Shi, Q; Yang, PC; Yang, SC; Yang, X; Zhao, G1
Barnard, DL; Chao, YS; Huang, CW; Jan, JT; Kang, IJ; Lee, SJ; Lee, YZ; Lin, D; Yang, CW; Yeh, TK1
Liu, Y; Park, CM; Xu, X1
Opatz, T; Peez, TE; Stoye, A1
Chang, HY; Chao, YS; Hsu, HY; Lee, SJ; Lee, YZ; Wu, CM; Yang, CW1
Liu, Y; Wang, Q; Zheng, Y1
Deng, M; Su, B; Wang, Q; Zhang, H1
Anton-Torrecillas, C; Gonzalez-Gomez, JC1
Liu, GQ; Opatz, T; Reimann, M1
Yamaoka, Y1
Abdalla, AN; Abdullah, O; Chen, L; Fischer, PM; Guise, CP; Liu, Y; Omran, Z; Patterson, AV; Rauch, C; Sindi, IA; Smaill, JB; Wang, Q1

Reviews

1 review(s) available for tylophorine and 1,7-phenanthroline

ArticleYear
Efficient Synthesis of Polyaromatic Hydrocarbon via a Formal [2+2] Cycloaddition.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2016, Volume: 136, Issue:11

    Topics: Alkaloids; Cyclization; Cycloaddition Reaction; Heterocyclic Compounds; Hydrogenation; Indolizines; Phenanthrenes; Phenanthrolines; Polycyclic Aromatic Hydrocarbons

2016

Other Studies

12 other study(ies) available for tylophorine and 1,7-phenanthroline

ArticleYear
Expedient synthesis and structure-activity relationships of phenanthroindolizidine and phenanthroquinolizidine alkaloids.
    Organic & biomolecular chemistry, 2006, Mar-07, Volume: 4, Issue:5

    Topics: Alkaloids; Antineoplastic Agents; Biochemistry; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Indolizines; Phenanthrenes; Phenanthrolines; Quinolizines; Structure-Activity Relationship

2006
Total syntheses of the tylophora alkaloids cryptopleurine, (-)-antofine, (-)-tylophorine, and (-)-ficuseptine C.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2006, Sep-25, Volume: 12, Issue:28

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Indoles; Indolizines; Phenanthrenes; Phenanthrolines

2006
Antitumor agents 268. Design, synthesis, and mechanistic studies of new 9-substituted phenanthrene-based tylophorine analogues as potent cytotoxic agents.
    Journal of medicinal chemistry, 2009, Aug-27, Volume: 52, Issue:16

    Topics: Alkaloids; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Indolizines; Models, Molecular; Molecular Conformation; NF-kappa B; Phenanthrenes; Phenanthrolines; Piperidines; Proto-Oncogene Proteins c-akt; Signal Transduction; Stereoisomerism; Structure-Activity Relationship

2009
Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus.
    Antiviral research, 2010, Volume: 88, Issue:2

    Topics: Alkaloids; Animals; Antiviral Agents; Apocynaceae; Chlorocebus aethiops; Coronavirus Infections; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Gastroenteritis, Transmissible, of Swine; Indolizines; Phenanthrenes; Phenanthrolines; Quinolizines; Rats; Rats, Sprague-Dawley; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Structure-Activity Relationship; Swine; Transmissible gastroenteritis virus; Tylophora; Vero Cells

2010
Rhodium(III)-catalyzed intramolecular annulation through C-H activation: total synthesis of (±)-antofine, (±)-septicine, (±)-tylophorine, and rosettacin.
    Angewandte Chemie (International ed. in English), 2012, Sep-10, Volume: 51, Issue:37

    Topics: Alkaloids; Alkynes; Carbon; Catalysis; Cyclization; Heterocyclic Compounds, 4 or More Rings; Hydrogen; Indoles; Indolizines; Isoquinolines; Phenanthrenes; Phenanthrolines; Pyridones; Rhodium; Stereoisomerism

2012
Left, right, or both? On the configuration of the phenanthroindolizidine alkaloid tylophorine from Tylophora indica.
    Journal of natural products, 2013, Feb-22, Volume: 76, Issue:2

    Topics: Alkaloids; Indolizines; Molecular Structure; Phenanthrenes; Phenanthrolines; Tylophora

2013
c-Jun-mediated anticancer mechanisms of tylophorine.
    Carcinogenesis, 2013, Volume: 34, Issue:6

    Topics: Activating Transcription Factor 1; Alkaloids; Antineoplastic Agents, Phytogenic; Carcinoma; Cell Line, Tumor; Cyclin A2; Down-Regulation; Elongation Factor 2 Kinase; Eukaryotic Initiation Factors; G1 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Indolizines; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; NF-kappa B; Phenanthrenes; Phenanthrolines; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C-delta; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-jun; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; RNA Interference; RNA, Small Interfering; Transcription Factor AP-1; Tylophora

2013
Collective asymmetric synthesis of (-)-antofine, (-)-cryptopleurine, (-)-tylophorine, and (-)-tylocrebrine with tert-butanesulfinamide as a chiral auxiliary.
    The Journal of organic chemistry, 2014, Apr-18, Volume: 79, Issue:8

    Topics: Alkaloids; Butanes; Indoles; Indolizines; Isomerism; Molecular Structure; Phenanthrenes; Phenanthrolines; Stereoisomerism; Sulfonamides

2014
An enantioselective strategy for the total synthesis of (S)-tylophorine via catalytic asymmetric allylation and a one-pot DMAP-promoted isocyanate formation/Lewis acid catalyzed cyclization sequence.
    Organic & biomolecular chemistry, 2014, Jun-14, Volume: 12, Issue:22

    Topics: Alkaloids; Catalysis; Chemistry, Organic; Cyclization; Indolizines; Isocyanates; Lewis Acids; Phenanthrenes; Phenanthrolines; Pyridines; Stereoisomerism

2014
Short asymmetric synthesis of phenanthroindolizidines through chiral homoallylic sulfinamines.
    Organic & biomolecular chemistry, 2014, Sep-28, Volume: 12, Issue:36

    Topics: Alkaloids; Allyl Compounds; Amines; Indolizines; Molecular Structure; Oxidation-Reduction; Phenanthrenes; Phenanthrolines; Stereoisomerism; Sulfonium Compounds

2014
Total Synthesis of Phenanthroindolizidine Alkaloids by Combining Iodoaminocyclization with Free Radical Cyclization.
    The Journal of organic chemistry, 2016, 07-15, Volume: 81, Issue:14

    Topics: Alkaloids; Chemistry, Organic; Cyclization; Free Radicals; Indoles; Indolizines; Isoquinolines; Magnetic Resonance Spectroscopy; Phenanthrenes; Phenanthrolines; Pyrrolidines; Stereoisomerism; Structure-Activity Relationship; Temperature

2016
Design, Synthesis and In-Vitro Biological Evaluation of Antofine and Tylophorine Prodrugs as Hypoxia-Targeted Anticancer Agents.
    Molecules (Basel, Switzerland), 2021, Jun-01, Volume: 26, Issue:11

    Topics: Alkaloids; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; CHO Cells; Cricetulus; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Indoles; Indolizines; MCF-7 Cells; Molecular Structure; Phenanthrenes; Phenanthrolines; Prodrugs; Quaternary Ammonium Compounds; Structure-Activity Relationship; Tumor Hypoxia

2021