tv3326 has been researched along with rivastigmine in 6 studies
| Studies (tv3326) | Trials (tv3326) | Recent Studies (post-2010) (tv3326) | Studies (rivastigmine) | Trials (rivastigmine) | Recent Studies (post-2010) (rivastigmine) |
|---|---|---|---|---|---|
| 15 | 0 | 11 | 1,397 | 266 | 633 |
| Protein | Taxonomy | tv3326 (IC50) | rivastigmine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | 6.2943 | |
| Cholinesterase | Homo sapiens (human) | 1.1886 | |
| Acyl-CoA desaturase 1 | Rattus norvegicus (Norway rat) | 1.71 | |
| Acetylcholine receptor subunit epsilon | Rattus norvegicus (Norway rat) | 9 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 0.875 | |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | 0.875 | |
| Acetylcholinesterase | Mus musculus (house mouse) | 3.9833 | |
| Acetylcholinesterase | Homo sapiens (human) | 2.8567 | |
| Acetylcholinesterase | Bos taurus (cattle) | 0.62 | |
| Cholinesterase | Canis lupus familiaris (dog) | 6.27 | |
| Acetylcholinesterase | Rattus norvegicus (Norway rat) | 3.5012 | |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | 0.16 | |
| Beta-secretase 1 | Homo sapiens (human) | 7.72 | |
| Cholinesterase | Equus caballus (horse) | 2.1636 | |
| Cholinesterase | Mus musculus (house mouse) | 0.829 | |
| Carboxylic ester hydrolase | Rattus norvegicus (Norway rat) | 5.2767 | |
| Carboxylic ester hydrolase | Equus caballus (horse) | 0.495 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chorev, M; Finberg, J; Finkelstein, N; Friedman, R; Goldenberg, W; Goren, T; Gross, A; Herzig, Y; Huang, W; Krais, B; Lavian, G; Lerner, D; Miskolczi, I; Molnar, S; Rantal, F; Razin, M; Sterling, J; Tamas, T; Toth, G; Weinstock, M; Youdim, MB; Zagyva, A; Zekany, A | 1 |
| Bolognesi, ML; Cavalli, A; Melchiorre, C; Minarini, A; Recanatini, M; Rosini, M; Tumiatti, V | 1 |
| Finkin-Groner, E; Ginsburg, I; Lerman, L; Nudelman, A; Shalom, H; Weill, T; Weinstock, M; Yanovsky, I; Zaikin, A; Zeeli, S | 1 |
| Kumar, A; Mishra, P; Panda, G | 1 |
| Feng, F; He, S; Jiang, H; Jiang, X; Liu, W; Qu, W; Sun, H; Zhou, J | 1 |
| do Carmo Carreiras, M; Ismaili, L; Marco-Contelles, J | 1 |
4 review(s) available for tv3326 and rivastigmine
| Article | Year |
|---|---|
Multi-target-directed ligands to combat neurodegenerative diseases.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Calcium Channel Blockers; Chelating Agents; Cholinesterase Inhibitors; Humans; Huntington Disease; Ligands; Multiple Sclerosis; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurotransmitter Agents; Parkinson Disease; Plaque, Amyloid | 2008 |
Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018).
Topics: Alzheimer Disease; Animals; Cholinesterase Inhibitors; Cholinesterases; Drug Design; Humans; Ligands; Neuroprotective Agents | 2019 |
Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms.
Topics: Animals; Drug Combinations; Drug Delivery Systems; Drug Design; Humans; Ligands | 2019 |
Propargylamine-derived multi-target directed ligands for Alzheimer's disease therapy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Cholinesterases; Humans; Ligands; Monoamine Oxidase; Neuroprotective Agents; Oxidative Stress; Pargyline; Propylamines | 2020 |
2 other study(ies) available for tv3326 and rivastigmine
| Article | Year |
|---|---|
Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Butyrylcholinesterase; Carbamates; Cattle; Cholinesterase Inhibitors; Humans; Indans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Phenethylamines; Propylamines; Structure-Activity Relationship | 2002 |
Carbamate derivatives of indolines as cholinesterase inhibitors and antioxidants for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Antioxidants; Apoptosis; Carbamates; Chickens; Cholinesterase Inhibitors; Humans; Indoles; Neurons | 2012 |