tv3326 has been researched along with rasagiline in 6 studies
| Studies (tv3326) | Trials (tv3326) | Recent Studies (post-2010) (tv3326) | Studies (rasagiline) | Trials (rasagiline) | Recent Studies (post-2010) (rasagiline) |
|---|---|---|---|---|---|
| 15 | 0 | 11 | 535 | 72 | 314 |
| Protein | Taxonomy | tv3326 (IC50) | rasagiline (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 2.3865 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 1.0029 | |
| Amine oxidase [flavin-containing] A | Rattus norvegicus (Norway rat) | 0.2115 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 1.088 | |
| Acetylcholinesterase | Homo sapiens (human) | 0.019 | |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | 0.2217 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chorev, M; Finberg, J; Finkelstein, N; Friedman, R; Goldenberg, W; Goren, T; Gross, A; Herzig, Y; Huang, W; Krais, B; Lavian, G; Lerner, D; Miskolczi, I; Molnar, S; Rantal, F; Razin, M; Sterling, J; Tamas, T; Toth, G; Weinstock, M; Youdim, MB; Zagyva, A; Zekany, A | 1 |
| Binda, C; Edmondson, DE; Herzig, Y; Hubálek, F; Li, M; Mattevi, A; Sterling, J; Youdim, MB | 1 |
| Bolognesi, ML; Cavalli, A; Melchiorre, C; Minarini, A; Recanatini, M; Rosini, M; Tumiatti, V | 1 |
| Huang, L; Jiang, H; Li, X; Lu, C; Luo, Z; Mao, F; Shan, W; Su, T; Sun, Y | 1 |
| Feng, F; He, S; Jiang, H; Jiang, X; Liu, W; Qu, W; Sun, H; Zhou, J | 1 |
| Affini, A; Hagenow, S; Lutsenko, K; Reiner, D; Stark, H | 1 |
2 review(s) available for tv3326 and rasagiline
| Article | Year |
|---|---|
Multi-target-directed ligands to combat neurodegenerative diseases.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Calcium Channel Blockers; Chelating Agents; Cholinesterase Inhibitors; Humans; Huntington Disease; Ligands; Multiple Sclerosis; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurotransmitter Agents; Parkinson Disease; Plaque, Amyloid | 2008 |
Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms.
Topics: Animals; Drug Combinations; Drug Delivery Systems; Drug Design; Humans; Ligands | 2019 |
4 other study(ies) available for tv3326 and rasagiline
| Article | Year |
|---|---|
Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Binding Sites; Butyrylcholinesterase; Carbamates; Cattle; Cholinesterase Inhibitors; Humans; Indans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Phenethylamines; Propylamines; Structure-Activity Relationship | 2002 |
Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues.
Topics: Alkynes; Circular Dichroism; Humans; Indans; Kinetics; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Structure-Activity Relationship | 2004 |
Multitarget-directed benzylideneindanone derivatives: anti-β-amyloid (Aβ) aggregation, antioxidant, metal chelation, and monoamine oxidase B (MAO-B) inhibition properties against Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Antioxidants; Benzylidene Compounds; Cations, Divalent; Chelating Agents; Copper; Humans; Indans; Iron; Isoenzymes; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Peptide Fragments; Recombinant Proteins; Structure-Activity Relationship; Zinc | 2012 |
Rasagiline derivatives combined with histamine H
Topics: Histamine H3 Antagonists; Humans; Indans; Monoamine Oxidase Inhibitors; Parkinson Disease; Receptors, Histamine H3 | 2019 |