tubercidin has been researched along with homocysteine in 71 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 42 (59.15) | 18.7374 |
| 1990's | 12 (16.90) | 18.2507 |
| 2000's | 17 (23.94) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bader, JP; Cantoni, GL; Chiang, PK; Montgomery, JA; Shannon, WM; Thomas, HJ | 1 |
| Duncan, GS; Wolberg, G; Zimmerman, TP | 1 |
| Chang, CD; Coward, JK | 1 |
| Doherty, NS; Gieske, TH; Raddatz, R; Stephens, D | 1 |
| Aarbakke, J; Bang, BE; Endresen, PC; Møller, C; Prytz, PS | 1 |
| Ariyoshi, S; Fujisue, T; Ichida, S; Yoshioka, K | 1 |
| Benyon, RC; Church, MK; Holgate, ST | 2 |
| Lefort, J; Randon, J; Vargaftig, BB | 1 |
| Hua, P; Nuske, JH | 1 |
| Djurhuus, R; Svardal, AM; Ueland, PM | 1 |
| Henson, PM; Riches, DW; Stanworth, DR; Watkins, JL | 1 |
| Llanos, MN; Pino, AM; Ronco, AM; Valladares, LE | 1 |
| Bowman, BJ; Smith, RJ; Speziale, SC; Ulrich, RG | 1 |
| Ariyoshi, S; Ichida, S; Okazaki, Y; Sobue, K; Tanaka, T; Yoshioka, K | 1 |
| Bardin, CW; Miller, RL; Tezon, J | 1 |
| Ariyoshi, S; Ichida, S; Moriyama, M; Yoshioka, K | 1 |
| Ariyoshi, S; Ichida, S; Oda, Y; Oka, H; Yoshioka, K | 1 |
| Ichida, S | 1 |
| Djurhuus, R; Svardal, A; Ueland, PM | 1 |
| Brovold, AB; Hetland, O; Prydz, H | 1 |
| Romstedt, K | 1 |
| Chiang, PK; Morita, Y; Siraganian, RP | 1 |
| Morita, Y; Siraganian, RP | 1 |
| Adams, JK; Allan, RG; Cooper, IA; Woodcock, DM | 1 |
| Evensen, SA; Galdal, KS; Lyberg, T; Nilsen, E; Prydz, H | 1 |
| Christoffersen, T; Døskeland, SO; Ogreid, D; Refsnes, M; Sand, TE; Schanche, JS; Ueland, PM | 1 |
| Axelrod, J; Bareis, DL; Hirata, F; Schiffmann, E | 1 |
| Mizel, D; Pick, E | 1 |
| Hattori, H; Kanfer, JN | 1 |
| Best, L; Garcia-Morales, P; Herchuelz, A; Hubinont, C; Juvent, M; Lebrun, P; Malaisse, WJ; Malaisse-Lagae, F; Saceda, M; Valverde, I | 1 |
| Hoffman, RM; Stern, PH | 1 |
| Chignard, M; Dray, F; Lecompte, T; Randon, J; Vargaftig, BB | 2 |
| Chignard, M; Jacquemin, C; Touqui, L; Vargaftig, BB; Wal, F | 1 |
| Chiang, PK | 1 |
| Ueland, PM | 1 |
| Chignard, M; Dray, F; Lecompte, T; Marlas, G; Randon, J; Siess, W; Vargaftig, BB | 1 |
| Chignard, M; Marlas, G; Randon, J; Vargaftig, BB | 1 |
| Helland, S; Ueland, PM | 1 |
| Braun, J; Rosen, FS; Unanue, ER | 1 |
| Aksamit, RR; Cantoni, GL; Falk, W | 1 |
| Elion, GB; Medzihradsky, JL; Wolberg, G; Zimmerman, TP | 1 |
| Meizel, S | 1 |
| McGee, R; Rabe, CS; Williams, TP | 1 |
| Linder, M; Scholtissek, C; Woyciniuk, P | 1 |
| Aarbakke, J; Eide, TJ; Endresen, PC; Fandrem, J | 1 |
| Aarbakke, J; Endresen, PC; Lysne, S; Prytz, PS | 1 |
| Aarbakke, J; Eide, TJ; Endresen, PC | 1 |
| Aarbakke, J; Endresen, PC; Kildalsen, H; Loennechen, T | 1 |
| Carotti, D; Lucarelli, M; Palitti, F; Scarpa, S; Strom, R | 1 |
| al-Khafaji, F; Bowron, A; Day, AP; Scott, J; Stansbie, D | 1 |
| Bowron, A; Day, AP; Scott, J; Stansbie, D; Woltersdorf, WW | 1 |
| Dawling, S | 1 |
| Ashizawa, K; Miyamoto, M; Tsuzuki, Y | 1 |
| Abbracchio, MP; Camurri, A; Ceruti, S; Falzano, L; Fiorentini, C; Frank, C; Giammarioli, AM; Malorni, W; Rufini, S | 1 |
| Bisse, E; Nauck, M; Wieland, H | 1 |
| Gibert, MJ; Malo, O; Martín, I; Obrador, A; Pintos, C; Vila, M | 1 |
| Chen, YF; Li, PL; Zou, AP | 1 |
| Burns, PJ; Harmening, DM; Hill, DM; Johnson, LJ; Kenney, AC; Neale, AM | 1 |
| Pagani, F; Panteghini, M | 1 |
| Bohle, RM; Braun-Dullaeus, RC; Dreyer, T; Fink, L; Haberbosch, W; Jeide, I; Langheinrich, AC; Schilling, R; Tammoscheit, K; Walker, G | 1 |
| Ashline, D; Milhalik, S; Ortiz, D; Rogers, E; Shea, TB | 1 |
| Han, Q; Hoffman, RM; Sun, X; Tan, Y; Tang, L; Xu, M; Zhang, N | 1 |
| Afman, LA; Blom, HJ; Brouns, MR; Drittij, MJ; van Straaten, HW | 1 |
| Chambers, MG; Mason, RM; Mistry, D | 1 |
| Lominadze, D; Moshal, KS; Ovechkin, AV; Sen, U; Steed, MM; Tyagi, N; Tyagi, SC | 1 |
| Hansrani, M; Stansby, G | 1 |
| Bea, F; Blessing, E; Isermann, B; Katus, HA; Kreuzer, J; Pedal, I; Preusch, MR; Rosenfeld, ME; Yang, SH | 1 |
| Kumar, M; Moshal, KS; Rodriguez, WE; Sen, U; Tyagi, N; Tyagi, SC | 1 |
| Ling, W; Mi, M; Yu, X | 1 |
1 review(s) available for tubercidin and homocysteine
| Article | Year |
|---|---|
Pharmacological and biochemical aspects of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Catalysis; Chemical Phenomena; Chemistry, Physical; Genes; Homocysteine; Humans; Hydrolases; Kinetics; Protein Binding; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; S-Adenosylhomocysteine; Substrate Specificity; Tubercidin | 1982 |
70 other study(ies) available for tubercidin and homocysteine
| Article | Year |
|---|---|
Adenosylhomocysteine hydrolase inhibitors: synthesis of 5'-deoxy-5'-(isobutylthio)-3-deazaadenosine and its effect on Rous sarcoma virus and Gross murine leukemia virus.
Topics: AKR murine leukemia virus; Antiviral Agents; Avian Sarcoma Viruses; Cell Transformation, Viral; Homocysteine; Hydrolases; Kinetics; S-Adenosylhomocysteine; Structure-Activity Relationship; Tubercidin; Virus Replication | 1978 |
Inhibition of lymphocyte-mediated cytolysis by 3-deazaadenosine: evidence for a methylation reaction essential to cytolysis.
Topics: Cyclic AMP; Cytotoxicity, Immunologic; Homocysteine; Immunity, Cellular; Isomerism; Methyltransferases; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; T-Lymphocytes; Tubercidin | 1978 |
Effect of S-adenosylhomocysteine and S-tubercidinylhomocysteine on transfer ribonucleic acid methylation in phytohemagglutinin-stimulated lymphocytes.
Topics: Animals; DNA; Homocysteine; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Male; Methylation; Rats; Rats, Inbred Strains; RNA, Transfer; S-Adenosylhomocysteine; Tubercidin | 1975 |
S-adenosylhomocysteine levels are not involved in the spasmolytic activity of 3-deazaadenosine in guinea-pig lung parenchyma.
Topics: Adenosine; Animals; Cyclic AMP; Cyclic GMP; Guinea Pigs; Homocysteine; In Vitro Techniques; Lung; Male; Parasympatholytics; S-Adenosylhomocysteine; SRS-A; Tubercidin | 1991 |
Elevation of cyclic AMP levels in HL-60 cells accumulated in G1 or G2 by transmethylation inhibitors.
Topics: Adenosine; Cell Division; Cell Line; Cyclic AMP; Flow Cytometry; G1 Phase; G2 Phase; Homocysteine; Humans; Leukemia; Methyltransferases; Tubercidin | 1991 |
Enhancement by L-methionine on the contractile response of uterine segments to acetylcholine and high KCl is mainly due to enhancement of Ca uptake.
Topics: Acetylcholine; Animals; Calcium; Female; Homocysteine; In Vitro Techniques; Methionine; Potassium Chloride; Pregnancy; Rats; Tubercidin; Uterine Contraction; Uterus | 1990 |
IgE-dependent activation of mast cells is not associated with enhanced phospholipid methylation.
Topics: Animals; Cyclic AMP; Histamine Release; Homocysteine; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Methionine; Methylation; Phosphatidylserines; Phospholipids; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Tritium; Tubercidin | 1986 |
Blockade by methylation inhibitors of the anaphylactic response of guinea-pig lung strips.
Topics: Adenosine; Airway Resistance; Anaphylaxis; Animals; Female; Guinea Pigs; Histamine Release; Homocysteine; In Vitro Techniques; Lung; Male; Methylation; Ovalbumin; Thromboxane B2; Tubercidin | 1987 |
IgE-dependent activation of human lung mast cells is not associated with increased phospholipid methylation.
Topics: Antibodies, Anti-Idiotypic; Calcimycin; Cyclic AMP; Histamine Release; Homocysteine; Humans; Immunoglobulin E; Lung; Mast Cells; Methylation; Phospholipids; Tubercidin | 1988 |
Invertebrate phototransduction: involvement of cytoskeletal elements.
Topics: Animals; Astacoidea; Cattle; Colchicine; Cytoskeleton; Fibroblasts; Homocysteine; Horseshoe Crabs; Invertebrates; Isomerism; Membrane Potentials; Methyltransferases; Photoreceptor Cells; Retina; S-Adenosylhomocysteine; Signal Transduction; Tubercidin | 1989 |
Differential effects on growth, homocysteine, and related compounds of two inhibitors of S-adenosylhomocysteine catabolism, 3-deazaadenosine, and 3-deazaaristeromycin, in C3H/10T1/2 cells.
Topics: Adenosine; Aminoglycosides; Animals; Anti-Bacterial Agents; Cell Division; Cell Line; Dose-Response Relationship, Drug; Glutathione; Glutathione Disulfide; Homocysteine; Mice; Mice, Inbred C3H; S-Adenosylhomocysteine; Tubercidin | 1989 |
Regulation of macrophage lysosomal secretion by adenosine, adenosine phosphate esters, and related structural analogues of adenosine.
Topics: Adenine; Adenine Nucleotides; Adenosine; Animals; Esterases; Homocysteine; Kinetics; Lysosomes; Macrophages; Male; Mice; Receptors, Cell Surface; Receptors, Purinergic; Secretory Rate; Structure-Activity Relationship; Theophylline; Tubercidin | 1985 |
The transmethylations inhibitor 3-deazaadenosine, inhibits in vitro testosterone production by rat testis interstitial cells stimulated with HCG.
Topics: Animals; Bucladesine; Chorionic Gonadotropin; Drug Synergism; Homocysteine; Leydig Cells; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, LH; Ribonucleosides; Testosterone; Tubercidin | 1985 |
Characteristics of aggregated immunoglobulin G as an immunologic phagocytic stimulus for granule enzyme release from human neutrophils.
Topics: Calcium; Calcium Channel Blockers; Cycloheximide; Cytoplasmic Granules; Dose-Response Relationship, Drug; Exocytosis; Homocysteine; Humans; Immunoglobulin G; Magnesium; Muramidase; Neutrophils; Peroxidase; Phagocytosis; Secretory Rate; Tubercidin | 1986 |
General characteristics of the superprecipitation reaction of rat crude uterine myosin B: effects of L-methionine and/or transmethylation blockers on the reaction.
Topics: Animals; Chemical Precipitation; Chickens; Electrophoresis, Polyacrylamide Gel; Female; Homocysteine; Methionine; Methylation; Myosins; Rats; Rats, Inbred Strains; Tubercidin; Uterus | 1987 |
Phospholipid methylation in starfish spermatozoa is linked to sperm chemoattraction.
Topics: Animals; Chemotaxis; Female; Homocysteine; Male; Membrane Lipids; Methylation; Methyltransferases; Ovum; Phospholipids; Sperm-Ovum Interactions; Spermatozoa; Starfish; Tubercidin | 1986 |
Enhancement by L-methionine of contractile responses to acetylcholine and high KCl in uterine segment.
Topics: Acetylcholine; Animals; Calcium; Female; Homocysteine; In Vitro Techniques; Methionine; Methyltransferases; Muscle, Smooth; Ovariectomy; Phosphatidyl-N-Methylethanolamine N-Methyltransferase; Phosphatidylethanolamine N-Methyltransferase; Potassium Chloride; Protein O-Methyltransferase; Rats; Tubercidin; Uterine Contraction; Uterus | 1987 |
L-methionine enhances the contractile response to norepinephrine of rat vas deferens.
Topics: Animals; Calcium; Female; Guinea Pigs; Homocysteine; In Vitro Techniques; Male; Methionine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Tubercidin; Vas Deferens | 1987 |
L-methionine enhances the contractile responses of rat uterine smooth muscle to acetylcholine and high KCl.
Topics: Acetylcholine; Animals; Calcium Chloride; Female; Homocysteine; In Vitro Techniques; Methionine; Methylation; Phospholipids; Potassium Chloride; Proteins; Rats; Rats, Inbred Strains; Tubercidin; Uterine Contraction | 1986 |
Disposition of homocysteine and S-3-deazaadenosylhomocysteine in cells exposed to 3-deazaadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Fibroblasts; Homocysteine; Hydrolases; Liver; Mice; Neoplasms, Experimental; Protein Binding; Rats; Ribonucleosides; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1986 |
Inhibitory effect of 3-deazaadenosine on the thromboplastin response of stimulated human monocytes.
Topics: Dose-Response Relationship, Drug; Homocysteine; Humans; In Vitro Techniques; Methylation; Monocytes; Phytohemagglutinins; Ribonucleosides; Thromboplastin; Tubercidin | 1985 |
3-Deazaadenosine and L-homocysteine inhibit human platelet activation induced by arachidonic acid, U46619 and phospholipase C.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acids; Blood Platelets; Cyclic AMP; Homocysteine; Humans; Isomerism; Methylation; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Ribonucleosides; Thrombin; Tubercidin; Type C Phospholipases | 1984 |
Effect of inhibitors of transmethylation on histamine release from human basophils.
Topics: Adenine; Adenosine; Basophils; Calcimycin; Histamine Release; Homocysteine; Humans; Immunoglobulin E; In Vitro Techniques; Methylation; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1981 |
Inhibition of IgE-mediated histamine release from rat basophilic leukemia cells and rat mast cells by inhibitors of transmethylation.
Topics: Adenine; Adenosine; Animals; Basophils; Female; Histamine Release; Homocysteine; Immunoglobulin E; Leukemia; Mast Cells; Methylation; Mice; Rabbits; Rats; Rats, Inbred Strains; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1981 |
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; Cytosine; Deoxyadenosines; DNA; DNA Replication; Ethionine; Homocysteine; Humans; Methylation; Thionucleosides; Tubercidin | 1983 |
Inhibition of the thromboplastin response of endothelial cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium; Endotoxins; Gallic Acid; Homocysteine; Humans; In Vitro Techniques; Tetradecanoylphorbol Acetate; Thromboplastin; Tubercidin | 1984 |
Evidence against a requirement for phospholipid methylation in adenylate cyclase activation by hormones. Methyltransferase inhibitors do not impair cyclic AMP accumulation induced by glucagon or beta-adrenergic agents in rat hepatocytes.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Epinephrine; Glucagon; Homocysteine; Isomerism; Isoproterenol; Liver; Methyltransferases; Phospholipids; Rats; S-Adenosylhomocysteine; Tubercidin | 1982 |
Phospholipid metabolism, calcium flux, and the receptor-mediated induction of chemotaxis in rabbit neutrophils.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Chemotaxis; Fatty Acids; Homocysteine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phospholipids; Rabbits; Receptors, Cell Surface; Receptors, Formyl Peptide; Tubercidin | 1982 |
Role of transmethylation in the elicitation of an oxidative burst in macrophages.
Topics: Adenosine; Animals; Concanavalin A; Depression, Chemical; Guinea Pigs; Homocysteine; Lectins; Macrophage Activation; Macrophages; Methylation; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Oxygen; Superoxides; Tubercidin; Wheat Germ Agglutinins | 1982 |
Inhibition of rat brain microsomal Na+,K+-ATPase by S-adenosylmethionine.
Topics: Animals; Brain; Homocysteine; Lipid Metabolism; Methylation; Microsomes; Rats; S-Adenosylmethionine; Sodium-Potassium-Exchanging ATPase; Tubercidin | 1984 |
Impairment of insulin release by methylation inhibitors.
Topics: Animals; Calcium; Homocysteine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lipid Metabolism; Methylation; Oxidation-Reduction; Phosphatidylinositols; Proteins; Rats; Ribonucleosides; Tubercidin | 1984 |
Elevated overall rates of transmethylation in cell lines from diverse human tumors.
Topics: Adenosylhomocysteinase; Cell Line; Homocysteine; Humans; Hydrolases; Methionine; Methylation; Neoplasms, Experimental; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1984 |
Methylation inhibitors impair collagen-induced activation of human platelets.
Topics: Homocysteine; Humans; In Vitro Techniques; Isomerism; Methylation; Platelet Aggregation; Ribonucleosides; Tubercidin | 1983 |
Dissociation between inhibition of phospholipid methylation and production of PAF-acether by rabbit platelets.
Topics: Animals; Blood Platelets; Crotalid Venoms; Homocysteine; Kinetics; Lectins, C-Type; Methylation; Phospholipids; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Tubercidin | 1984 |
S-adenosylhomocysteine hydrolase as a pharmacological target for the inhibition of transmethylation.
Topics: Adenosine; Animals; Enzyme Inhibitors; Homocysteine; Isomerism; Kinetics; Mice; Ribonucleosides; S-Adenosylhomocysteine; Structure-Activity Relationship; Tubercidin | 1984 |
Dissociation of platelet activation from transmethylation of their membrane phospholipids.
Topics: Adenosine Diphosphate; Animals; Calcimycin; Collagen; Crotalid Venoms; Homocysteine; Immunoglobulin E; Kinetics; Lectins, C-Type; Male; Membrane Lipids; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Aggregation; Rats; Rats, Inbred Strains; Tubercidin | 1981 |
Interference of transmethylation inhibitors with thromboxane synthesis in rat platelets.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Homocysteine; Isomerism; Kinetics; Male; Methyltransferases; Rats; Rats, Inbred Strains; Ribonucleosides; Thromboxane B2; Thromboxanes; Tubercidin | 1982 |
3 Deazaadenosine and L-homocysteine inhibit platelet aggregation induced by collagen and convulxin through a phospholipase A2 independent mechanism.
Topics: Animals; Calcimycin; Collagen; Crotalid Venoms; Homocysteine; Lectins, C-Type; Male; Methylation; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Aggregation; Rats; Ribonucleosides; Tubercidin | 1982 |
Binding of adenosine to intracellular S-adenosylhomocysteine hydrolase in isolated rat hepatocytes.
Topics: Adenosine; Adenosine Deaminase; Adenosylhomocysteinase; Animals; Chromatography, High Pressure Liquid; Homocysteine; Hydrolases; Isoelectric Focusing; Liver; Rats; Tubercidin; Vidarabine | 1983 |
Capping and adenosine metabolism. Genetic and pharmacologic studies.
Topics: Adenosine; Adenosine Deaminase; Animals; Bone Marrow Transplantation; Coformycin; Contractile Proteins; Homocysteine; Humans; Immunologic Capping; Lymphocytes; Mice; Tubercidin | 1980 |
Inhibition of chemotaxis by S-3-deazaadenosylhomocysteine in a mouse macrophage cell line.
Topics: Animals; Cell Line; Chemotaxis; Homocysteine; Isomerism; Kinetics; Macrophages; Mice; S-Adenosylhomocysteine; Structure-Activity Relationship; Tubercidin | 1982 |
Immunosuppressive effects of the S-adenosylhomocysteine hydrolase inhibitor, 3-deazaadenosine.
Topics: Adenosylhomocysteinase; Animals; Antibody Formation; Homocysteine; Hydrolases; Immunity, Cellular; Immunosuppressive Agents; Lymphocytes; Male; Mice; Mice, Inbred CBA; Ribonucleosides; Sheep; Tubercidin | 1982 |
Inhibition of the hamster sperm acrosome reaction by transmethylation inhibitors.
Topics: Acrosome; Animals; Cricetinae; Homocysteine; In Vitro Techniques; Male; Mesocricetus; Methylation; Ribonucleosides; Sperm Capacitation; Sperm Motility; Spermatozoa; Tubercidin | 1981 |
Enhancement of depolarization-dependent release of norepinephrine by an inhibitor of S-adenosylmethionine-dependent transmethylations.
Topics: Adrenal Gland Neoplasms; Animals; Carbachol; Cell Line; Clone Cells; Homocysteine; Kinetics; Norepinephrine; Pheochromocytoma; Potassium; Ribonucleosides; S-Adenosylmethionine; Tubercidin | 1980 |
The methyltransferase inhibitor Neplanocin A interferes with influenza virus replication by a mechanism different from that of 3-deazaadenosine.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Chick Embryo; Drug Synergism; Homocysteine; Hydrolases; Influenza A virus; Methionine; Methyltransferases; RNA Caps; RNA, Viral; S-Adenosylhomocysteine; Tubercidin; Viral Proteins; Virus Replication | 1995 |
Morphological modifications of apoptosis in HL-60 cells: effects of homocysteine and cytochalasins on apoptosis initiated by 3-deazaadenosine.
Topics: Actins; Apoptosis; Cell Nucleus; Cytochalasin B; DNA Damage; Homocysteine; Humans; Microscopy, Electron; Tubercidin; Tumor Cells, Cultured; Vacuoles | 1995 |
Homocysteine increases the relative number of apoptotic cells and reduces the relative number of apoptotic bodies in HL-60 cells treated with 3-deazaadenosine.
Topics: Apoptosis; Cycloheximide; Dactinomycin; DNA; Homocysteine; Humans; Interphase; Leukemia, Promyelocytic, Acute; Tubercidin; Tumor Cells, Cultured | 1994 |
Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine.
Topics: Apoptosis; Cell Death; Chlorides; Flow Cytometry; Homocysteine; Humans; S Phase; Tubercidin; Tumor Cells, Cultured; Zinc Compounds | 1993 |
Apoptosis and transmethylation metabolites in HL-60 cells.
Topics: Adenosine; Apoptosis; DNA; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Homocysteine; Humans; Methylation; Methyltransferases; Nucleic Acid Synthesis Inhibitors; RNA; S-Adenosylhomocysteine; S-Adenosylmethionine; Tubercidin | 1996 |
Simultaneous myogenin expression and overall DNA hypomethylation promote in vitro myoblast differentiation.
Topics: Animals; Blotting, Northern; Blotting, Southern; Cell Differentiation; Cells, Cultured; DNA; DNA Methylation; Homocysteine; Muscle Fibers, Skeletal; Muscle, Skeletal; Myogenin; Polymerase Chain Reaction; Rats; RNA, Messenger; Stem Cells; Tubercidin | 1996 |
Stabilization of blood homocysteine by 3-deazaadenosine.
Topics: Biological Transport; Erythrocytes; Homocysteine; Humans; Tubercidin | 1998 |
Abbott IMx homocysteine assay: significant interference by 3-deazaadenosine.
Topics: Artifacts; Female; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Male; Tubercidin | 1999 |
Stabilizing blood with 3-deazaadenosine interferes in the Abbott FPIA assay for plasma homocyst(e)ine.
Topics: Fluorescence Polarization Immunoassay; Homocysteine; Homocystine; Humans; Tubercidin | 1999 |
The possible role of protein-carboxyl methylation in the regulation of flagellar movement of fowl spermatozoa.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium Chloride; Chickens; Enzyme Inhibitors; Homocysteine; Luminescent Measurements; Male; Marine Toxins; Methylation; Oxazoles; Proteins; Semen; Sperm Motility; Sperm Tail; Tubercidin | 2000 |
Adenosine- and 2-chloro-adenosine-induced cytopathic effects on myoblastic cells and myotubes: involvement of different intracellular mechanisms.
Topics: 2-Chloroadenosine; Acetylcysteine; Actin Cytoskeleton; Adenosine; Adenosine Kinase; Animals; Apoptosis; Cell Adhesion; Cell Line; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Homocysteine; Intracellular Fluid; Mice; Microscopy, Electron, Scanning; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Thioinosine; Tubercidin | 2000 |
Pre-analytical conditions affecting the determination of the plasma homocysteine concentration.
Topics: Chemistry, Clinical; Citrates; Edetic Acid; Homocysteine; Humans; Risk Factors; Sodium Fluoride; Specimen Handling; Temperature; Time Factors; Tubercidin | 2001 |
Stabilization of blood homocysteine in an epidemiological setting.
Topics: Drug Interactions; Fluorescence Polarization Immunoassay; Homocysteine; Humans; Isomerism; Tubercidin | 2001 |
Effect of hyperhomocysteinemia on plasma or tissue adenosine levels and renal function.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Fluorescence; Hemodynamics; Homocysteine; Hydrolases; Hyperhomocysteinemia; Kidney; Rats; Rats, Sprague-Dawley; Reference Standards; Risk Factors; Tubercidin | 2002 |
Effects of temperature on stability of blood homocysteine in collection tubes containing 3-deazaadenosine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Specimen Collection; Female; Homocysteine; Humans; Indicators and Reagents; Male; Middle Aged; Temperature; Time Factors; Tubercidin | 2002 |
On the comparison of serum and plasma samples in troponin assays.
Topics: Adenosylhomocysteinase; Blood Specimen Collection; Homocysteine; Humans; Hydrolases; Temperature; Time Factors; Tubercidin | 2003 |
Effects of 3-deazaadenosine on homocysteine and atherosclerosis in apolipoprotein E-deficient mice.
Topics: Analysis of Variance; Animals; Apolipoproteins E; Arteriosclerosis; Base Sequence; Biopsy, Needle; Cholesterol; Diet, Atherogenic; Disease Models, Animal; DNA, Complementary; Flow Cytometry; Homocysteine; Immunohistochemistry; Male; Mice; Mice, Knockout; Molecular Sequence Data; Polymerase Chain Reaction; Probability; Reference Values; RNA, Messenger; Sinus of Valsalva; Transaminases; Tubercidin; Tunica Intima | 2003 |
The S-adenosyl homocysteine hydrolase inhibitor 3-deaza-adenosine prevents oxidative damage and cognitive impairment following folate and vitamin E deprivation in a murine model of age-related, oxidative stress-induced neurodegeneration.
Topics: Adenosylhomocysteinase; Animals; Apolipoproteins E; Brain; Brain Chemistry; Cognition Disorders; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Female; Folic Acid Deficiency; Homocysteine; Male; Methionine; Mice; Mice, Knockout; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Tubercidin; Vitamin E Deficiency | 2004 |
3-Deazaadenosine, a stabilizer of whole-blood homocysteine content, does not interfere with the single-enzyme homocysteine assay while totally inhibiting the enzyme conversion homocysteine immunoassay.
Topics: Homocysteine; Humans; Immunoenzyme Techniques; Lyases; S-Adenosylhomocysteine; Tubercidin | 2004 |
Inhibition of transmethylation disturbs neurulation in chick embryos.
Topics: Adenosine; Adenosylhomocysteinase; Animals; Chick Embryo; Cycloleucine; Dose-Response Relationship, Drug; Drug Interactions; Embryonic Development; Homocysteine; Methylation; Models, Biological; Nervous System; Organogenesis; S-Adenosylhomocysteine; Time Factors; Tubercidin | 2005 |
The role of adenosine in chondrocyte death in murine osteoarthritis and in a murine chondrocyte cell line.
Topics: 5'-Nucleotidase; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Apoptosis; Cartilage, Articular; Cell Death; Cell Line; Chondrocytes; DNA Fragmentation; Enzyme Inhibitors; Homocysteine; Male; Mice; Mice, Inbred Strains; Osteoarthritis; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Tubercidin | 2006 |
3-Deazaadenosine mitigates arterial remodeling and hypertension in hyperhomocysteinemic mice.
Topics: Animals; Antibiotics, Antineoplastic; Aorta; Blood Pressure; Connexin 43; Cystathionine beta-Synthase; Echocardiography; Endothelium, Vascular; Extracellular Matrix; Female; Heart Rate; Homocysteine; Hyperhomocysteinemia; Hypertension; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred Strains; Mice, Knockout; Muscle, Smooth, Vascular; Reverse Transcriptase Polymerase Chain Reaction; Tubercidin | 2006 |
Extended storage of whole blood with 3-deazaadenosine for homocysteine assay.
Topics: Anticoagulants; Biological Assay; Blood Preservation; Blood Specimen Collection; Chromatography, High Pressure Liquid; Homocysteine; Humans; Isomerism; Time Factors; Tubercidin | 2007 |
Long-term administration of 3-deazaadenosine does not alter progression of advanced atherosclerotic lesions in apolipoprotein E-deficient mice.
Topics: Actins; Adenosine; Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Female; Homocysteine; Intercellular Adhesion Molecule-1; Interleukin-10; Interleukin-1beta; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Transcription Factor AP-1; Tubercidin; Vascular Cell Adhesion Molecule-1 | 2007 |
Cystathionine-beta-synthase gene transfer and 3-deazaadenosine ameliorate inflammatory response in endothelial cells.
Topics: Animals; Cell Adhesion Molecules; Cells, Cultured; Collagen Type I; Cystathionine beta-Synthase; Endothelial Cells; Extracellular Matrix; Genetic Therapy; Homocysteine; Hyperhomocysteinemia; Inflammation Mediators; Matrix Metalloproteinase 9; Methionine; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Transfection; Tubercidin | 2007 |
Relationship of impairment induced by intracellular S-adenosylhomocysteine accumulation with DNA methylation in human umbilical vein endothelial cells treated with 3-deazaadenosine.
Topics: Apoptosis; Atherosclerosis; Cell Proliferation; Chemokine CCL2; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Endothelial Cells; Estrogen Receptor alpha; Gene Expression; Homocysteine; Humans; Infant, Newborn; Intracellular Membranes; L-Lactate Dehydrogenase; Microscopy, Electron; Promoter Regions, Genetic; RNA, Messenger; S-Adenosylhomocysteine; Superoxide Dismutase; Tubercidin; Umbilical Veins | 2009 |