tryptophan and sirolimus

tryptophan has been researched along with sirolimus in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Prendergast, FG; Silva, ND1
Craescu, CT; Gallay, J; Rouviere, N; Vincent, M1
Chen, J; Fang, Y; Nuzzi, P; Vilella-Bach, M1
Beck, T; Hall, MN; Schmidt, A1
Abe, F; Horikoshi, K1
Christie, GR; Hajduch, E; Hundal, HS; Proud, CG; Taylor, PM1
Buckle, AM; Fulton, KF; Jackson, SE1
Chen, X; Duan, Y; Wu, H; Xu, Z; Zhang, W; Zhu, X1
Brandacher, G; Fuchs, D; Kurz, K; Schroecksnadel, S; Sucher, R1

Other Studies

11 other study(ies) available for tryptophan and sirolimus

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
Tryptophan dynamics of the FK506 binding protein: time-resolved fluorescence and simulations.
    Biophysical journal, 1996, Volume: 70, Issue:3

    Topics: Biophysical Phenomena; Biophysics; Carrier Proteins; Circular Dichroism; Crystallography, X-Ray; DNA-Binding Proteins; Fluorescence Polarization; Heat-Shock Proteins; Humans; Immunosuppressive Agents; In Vitro Techniques; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Polyenes; Protein Conformation; Sirolimus; Spectrophotometry; Tacrolimus; Tacrolimus Binding Proteins; Thermodynamics; Tryptophan

1996
Immunosuppressor binding to the immunophilin FKBP59 affects the local structural dynamics of a surface beta-strand: time-resolved fluorescence study.
    Biochemistry, 1997, Jun-17, Volume: 36, Issue:24

    Topics: Acrylamide; Acrylamides; Carrier Proteins; DNA-Binding Proteins; Fluorescence Polarization; Heat-Shock Proteins; Immunosuppressive Agents; Models, Molecular; Polyenes; Protein Structure, Secondary; Sirolimus; Spectrometry, Fluorescence; Tacrolimus; Tacrolimus Binding Proteins; Temperature; Thermodynamics; Tryptophan

1997
The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression.
    The Journal of biological chemistry, 1999, Feb-12, Volume: 274, Issue:7

    Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Carrier Proteins; Catalysis; Cell Line; G1 Phase; Humans; Immunophilins; Immunosuppressive Agents; Microinjections; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; S Phase; Sequence Homology, Amino Acid; Serine; Sirolimus; Tacrolimus Binding Proteins; TOR Serine-Threonine Kinases; Tryptophan; Tumor Cells, Cultured

1999
Starvation induces vacuolar targeting and degradation of the tryptophan permease in yeast.
    The Journal of cell biology, 1999, Sep-20, Volume: 146, Issue:6

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Biological Transport; Cell Membrane; Endocytosis; Endopeptidases; Endoplasmic Reticulum; Escherichia coli Proteins; Gene Expression Regulation, Fungal; Genes, Fungal; Golgi Apparatus; Half-Life; Membrane Transport Proteins; Molecular Sequence Data; Mutation; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Tryptophan; Ubiquitins; Vacuoles

1999
Tryptophan permease gene TAT2 confers high-pressure growth in Saccharomyces cerevisiae.
    Molecular and cellular biology, 2000, Volume: 20, Issue:21

    Topics: Amino Acid Transport Systems; Blotting, Western; Cell Cycle; Cell Division; DNA Restriction Enzymes; Dose-Response Relationship, Drug; Down-Regulation; Escherichia coli Proteins; Flow Cytometry; Fungal Proteins; G1 Phase; Hydrostatic Pressure; Immunosuppressive Agents; Membrane Transport Proteins; Phosphorylation; Plasmids; Protein Kinases; ras GTPase-Activating Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Sirolimus; Temperature; Thermodynamics; Time Factors; Tryptophan

2000
Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner.
    The Journal of biological chemistry, 2002, Mar-22, Volume: 277, Issue:12

    Topics: Alanine; Alcohols; Amino Acid Motifs; Amino Acids; Animals; Blotting, Western; Dose-Response Relationship, Drug; Glutamic Acid; Glutamine; Leucine; Oocytes; Phosphorylation; Protein Binding; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Time Factors; Tryptophan; Xenopus laevis

2002
Energetic and structural analysis of the role of tryptophan 59 in FKBP12.
    Biochemistry, 2003, Mar-04, Volume: 42, Issue:8

    Topics: Amino Acid Substitution; Crystallography, X-Ray; Humans; Hydrophobic and Hydrophilic Interactions; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Folding; Protein Isoforms; Recombinant Proteins; Sirolimus; Static Electricity; Structure-Activity Relationship; Tacrolimus Binding Protein 1A; Thermodynamics; Tryptophan

2003
Generation of high rapamycin producing strain via rational metabolic pathway-based mutagenesis and further titer improvement with fed-batch bioprocess optimization.
    Biotechnology and bioengineering, 2010, Oct-15, Volume: 107, Issue:3

    Topics: Fermentation; Glucose; Lysine; Metabolic Networks and Pathways; Mutagenesis; Phenylalanine; Shikimic Acid; Sirolimus; Streptomyces; Tryptophan; Ultraviolet Rays

2010
Influence of immunosuppressive agents on tryptophan degradation and neopterin production in human peripheral blood mononuclear cells.
    Transplant immunology, 2011, Volume: 25, Issue:2-3

    Topics: Cells, Cultured; Cyclosporine; GTP Cyclohydrolase; Humans; Immunosuppressive Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Methylprednisolone; Mycophenolic Acid; Neopterin; Phytohemagglutinins; Sirolimus; Tacrolimus; Tryptophan

2011