tryptophan and simvastatin

tryptophan has been researched along with simvastatin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Egashira, Y; Hirai, S; Koshiguchi, M; Matsuda, H; Sato, M; Yakushiji, M1
Carru, C; Mangoni, AA; Sanna, M; Satta, AE; Sotgia, S; Zinellu, A1
Liu, QZ; Shang, J; Wang, H; Wang, LL; Zhou, J1
Abbouda, A; Cunha, DL; Horneffer-van der Sluis, V; Mitsios, A; Moosajee, M; Owen, N; Richardson, R; Skinner, J; Takis, P; Tracey-White, D; Welch, AA1
Abraldes, JG; Alessandria, C; Beuers, U; Campion, D; Caraceni, P; Carol, M; Davis, MM; de Wit, K; Durand, F; Francoz, C; Ginès, P; Jiménez, C; Juanola, A; Kamath, PS; Kazankov, K; Lozano, JJ; Ma, AT; Mookerjee, RP; Morales-Ruiz, M; Napoleone, L; Piano, S; Pose, E; Sidorova, J; Solà, E; Tonon, M; Trebicka, J; Uschner, F; Vargas, V; Watson, H; Zaccherini, G1

Trials

2 trial(s) available for tryptophan and simvastatin

ArticleYear
Impact of cholesterol lowering treatment on plasma kynurenine and tryptophan concentrations in chronic kidney disease: relationship with oxidative stress improvement.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2015, Volume: 25, Issue:2

    Topics: Aged; Allantoin; Anticholesteremic Agents; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Ezetimibe; Female; Healthy Volunteers; Humans; Inflammation; Kynurenine; Male; Malondialdehyde; Middle Aged; NF-kappa B; Oxidative Stress; Renal Insufficiency, Chronic; Simvastatin; Taurine; Triglycerides; Tryptophan; Uric Acid

2015
Treatment With Simvastatin and Rifaximin Restores the Plasma Metabolomic Profile in Patients With Decompensated Cirrhosis.
    Hepatology communications, 2022, Volume: 6, Issue:5

    Topics: Acute-On-Chronic Liver Failure; Carnitine; Humans; Kynurenine; Liver Cirrhosis; Metabolomics; Rifaximin; Simvastatin; Tryptophan

2022

Other Studies

5 other study(ies) available for tryptophan and simvastatin

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Regulation of rat hepatic α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme in the tryptophan- NAD pathway, by dietary cholesterol and sterol regulatory element-binding protein-2.
    European journal of nutrition, 2014, Volume: 53, Issue:2

    Topics: Animals; Carboxy-Lyases; Cholesterol, Dietary; Gene Expression Regulation, Enzymologic; Hepatocytes; Hydroxycholesterols; Hypercholesterolemia; Liver; Male; Models, Animal; NAD; Rats; Rats, Sprague-Dawley; RNA, Messenger; Simvastatin; Sterol Regulatory Element Binding Protein 2; Tryptophan

2014
Simvastatin and Bezafibrate ameliorate Emotional disorder Induced by High fat diet in C57BL/6 mice.
    Scientific reports, 2017, 05-24, Volume: 7, Issue:1

    Topics: Animals; Behavior, Animal; Bezafibrate; Depression; Diet, High-Fat; Glucose Tolerance Test; Hindlimb Suspension; Hippocampus; Male; Mice; Serotonin; Signal Transduction; Simvastatin; Stress, Psychological; Swimming; Tryptophan

2017
REP1 deficiency causes systemic dysfunction of lipid metabolism and oxidative stress in choroideremia.
    JCI insight, 2021, 05-10, Volume: 6, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; Adult; Animals; Case-Control Studies; Choroideremia; Fenofibrate; Glycerophospholipids; Humans; Hypolipidemic Agents; Lipid Metabolism; Lipidomics; Male; Metabolomics; Middle Aged; Oxidative Stress; Prenylation; Serotonin; Simvastatin; Sphingolipids; Tryptophan; Young Adult; Zebrafish; Zebrafish Proteins

2021