tryptophan and s-adenosylmethionine

tryptophan has been researched along with s-adenosylmethionine in 49 studies

Research

Studies (49)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (8.16)	18.7374
1990's	3 (6.12)	18.2507
2000's	5 (10.20)	29.6817
2010's	27 (55.10)	24.3611
2020's	10 (20.41)	2.80

Authors

Authors	Studies
Bao, Y; Gao, P; Hong, CS; Jia, W; Luo, P; Tu, Y; Wei, L; Xu, G; Yin, P; Yu, H; Zhang, P; Zhao, X; Zhuang, Z	1
Ärlestig, L; Rantapää-Dahlqvist, S; Surowiec, I; Trygg, J	1
Chadeau-Hyam, M; Chatzi, L; Keski-Rahkonen, P; Kogevinas, M; Nawrot, T; Pizzi, C; Plusquin, M; Richiardi, L; Robinot, N; Robinson, O; Scalbert, A; Sunyer, J; Vermeulen, R; Vineis, P; Vrijheid, M	1
Auriola, S; Hanhineva, K; Heinonen, S; Jääskeläinen, T; Jokkala, J; Kärkkäinen, O; Laivuori, H; Lehtonen, M; Litonius, K	1
Console, L; Giangregorio, N; Indiveri, C; Pistillo, M; Scalera, V; Tonazzi, A	1
Caldez, MJ; Choi, H; Coppola, V; Eisenhaber, F; Goh, CMF; Gopinathan, L; Jones, OS; Kaldis, P; Kanagasundaram, Y; Kien, YL; Kurochkin, IV; Low, KN; Maurer-Stroh, S; Niska-Blakie, J; Ong, CB; Pfeiffenberger, E; Tessarollo, L	1
Clark, C; Delorenzi, M; Gallart-Ayala, H; Henry, H; Ivanisevic, J; Konz, I; Mehl, F; Oikonomidi, A; Peyratout, G; Popp, J; Teav, T; van der Velpen, V	1
Amatobi, KM; Fekete, A; Helfrich-Förster, C; Horn, M; Mueller, MJ; Rieger, D; Schäbler, S; Wegener, C	1
Becker, LB; Choi, J; Choudhary, RC; Hayashida, K; Kim, J; Kim, N; Nishikimi, M; Shoaib, M; Stevens, JF; Yagi, T; Yin, T	1
Akpan, IJ; Buehler, PW; Cendali, FI; D'Alessandro, A; Francis, RO; Gamboni, F; Hod, EA; Hudson, KE; Kahn, S; Katneni, U; Moriconi, C; Nemkov, T; Reisz, JA; Roh, D; Spitalnik, SL; Tanaka, K; Thangaraju, K; Thomas, T; Valk, JE; Wei, AZ; Zimring, JC	1
Goriaev, PP; Vikhert, AM; Zakharkina, GA	1
Gonzalez, L; Maegley, KA; Reich, NO; Smith, DW	1
Abou-Saleh, MT; Coppen, A	1
Bottiglieri, T; Nunn, JF; Rossiter, J; Sharer, NM	1
Gonnard, P	1
Kery, V; Kraus, JP; Poneleit, L	1
Encinas, MV; Saavedra, C; Vásquez, C	1
Young, SN	1
Casas, A; Del C Batlle, AM; Perotti, C	1
Klimasauskas, S; Merkiene, E	1
Kavanagh, DJ; Sarris, J; Schoendorfer, N	1
Filteau, MJ; Kennedy, SH; Lam, RW; Lespérance, F; Parikh, SV; Patten, SB; Ravindran, AV	1
Chen, D; Duan, L; Li, Y; Liu, W; Shen, B; Yu, Y; Zhang, Q	1
Arcinas, AJ; Booker, SJ	1
Chen, D; Liao, R; Lin, J; Liu, W; Tong, W; Xu, Z; Zhang, Q	1
Howland, RH	1
Benjdia, A; Berteau, O; Guillot, A; Langella, P; Pierre, S; Sandström, C	1
Chakrabarti, P; Chakravarty, D; Chatterjee, T; Dey, S; Pal, A; Saha, RP	1
Chan, KK; O'Hagan, D; Thompson, S	1
da Silva, TL; Ravindran, AV	1
Fujimori, DG	1
Blankenfeldt, W; Misson, L; Seebeck, FP; Vit, A	1
Brock, NL; Deng, Z; Kong, D; Lin, S; Xu, F; Zhang, L; Zhang, Z; Zou, Y	1
Bridwell-Rabb, J; Drennan, CL	1
Amara, P; Barra, AL; Fontecilla-Camps, JC; Gambarelli, S; Martin, L; Mouesca, JM; Nicolet, Y; Sicoli, G; Zeppieri, L	1
Hrydziuszko, O; Kirwan, J; Laing, R; Mirza, DF; Murphy, N; Perera, MT; Richards, DA; Silva, MA; Viant, MR	1
Begley, TP; Bhandari, DM; Fedoseyenko, D	2
Schramma, KR; Seyedsayamdost, MR	1
Blaszczyk, AJ; Booker, SJ; Ho, JV; Silakov, A; Wang, B	1
Blaszczyk, AJ; Booker, SJ; Wang, RX	1
Ji, X; Mandalapu, D; Zhang, Q	1
Blaszczyk, AJ; Booker, SJ; Knox, HL	1
Liu, F; Zhang, J	1
Blaszczyk, AJ; Booker, SJ; Chen, PY; Drennan, CL; Grove, TL; Knox, HL; Mukherjee, A; Schwalm, EL; Wang, B	1
Balo, AR; Britt, RD; Caruso, A; Seyedsayamdost, MR; Tantillo, DJ; Tao, L	1
Benjdia, A; Berteau, O; Brewee, C; Guillot, A; Guinchard, X; Haumann, M; Kubiak, X; Sabat, N; Soualmia, F	1
Amara, P; Martin, L; Mouesca, JM; Nicolet, Y; Saragaglia, C	1
Clark, KA; Seyedsayamdost, MR	1

Reviews

6 review(s) available for tryptophan and s-adenosylmethionine

Article	Year
The biology of folate in depression: implications for nutritional hypotheses of the psychoses. Journal of psychiatric research, 1986, Volume: 20, Issue:2 Topics: Anorexia Nervosa; Biogenic Amines; Brain; Depressive Disorder; Diet; Folic Acid; Folic Acid Deficiency; Homocystinuria; Humans; Models, Theoretical; Pellagra; Pterins; S-Adenosylmethionine; Schizophrenia; Tryptophan; Vitamin B 12 Deficiency	1986
[Current data on the lateral biochemical effects of dopa]. Pathologie-biologie, 1974, Volume: 22, Issue:3 Topics: Aminobutyrates; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Dopa Decarboxylase; Melatonin; Metabolism; Methylation; Polyribosomes; Protein Biosynthesis; Pyridoxal Phosphate; S-Adenosylmethionine; Stimulation, Chemical; Tryptophan; Tyrosine 3-Monooxygenase	1974
Clinical nutrition: 3. The fuzzy boundary between nutrition and psychopharmacology. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002, Jan-22, Volume: 166, Issue:2 Topics: Acetylcholine; Affect; Aggression; Behavior; Child, Preschool; Diet; Dietary Carbohydrates; Folic Acid; Humans; Male; Memory; S-Adenosylmethionine; Serotonin; Tryptophan	2002
Major depressive disorder and nutritional medicine: a review of monotherapies and adjuvant treatments. Nutrition reviews, 2009, Volume: 67, Issue:3 Topics: Amino Acids; Antidepressive Agents; Chemotherapy, Adjuvant; Depression; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Folic Acid; Humans; Nutritional Physiological Phenomena; Nutritional Status; S-Adenosylmethionine; Tryptophan	2009
Complementary and alternative therapies as add-on to pharmacotherapy for mood and anxiety disorders: a systematic review. Journal of affective disorders, 2013, Sep-25, Volume: 150, Issue:3 Topics: Anxiety Disorders; Combined Modality Therapy; Complementary Therapies; Fatty Acids, Omega-3; Female; Humans; Male; Meditation; Mood Disorders; Phototherapy; S-Adenosylmethionine; Tryptophan; Yoga	2013
Radical SAM-mediated methylation reactions. Current opinion in chemical biology, 2013, Volume: 17, Issue:4 Topics: Free Radicals; Methylation; RNA; S-Adenosylmethionine; Substrate Specificity; Tryptophan	2013

Other Studies

43 other study(ies) available for tryptophan and s-adenosylmethionine

Article	Year
Metabolomics Study of Roux-en-Y Gastric Bypass Surgery (RYGB) to Treat Type 2 Diabetes Patients Based on Ultraperformance Liquid Chromatography-Mass Spectrometry. Journal of proteome research, 2016, Apr-01, Volume: 15, Issue:4 Topics: Adult; Amino Acids; Bile Acids and Salts; Bilirubin; Biomarkers; Carnitine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Energy Metabolism; Fatty Acids, Nonesterified; Female; Gastric Bypass; Hippurates; Humans; Indican; Insulin Resistance; Male; Mass Spectrometry; Metabolomics; Middle Aged; Obesity, Morbid; Oxidative Stress; Prognosis; Remission Induction; Treatment Outcome; Tryptophan; Weight Loss	2016
Metabolite and Lipid Profiling of Biobank Plasma Samples Collected Prior to Onset of Rheumatoid Arthritis. PloS one, 2016, Volume: 11, Issue:10 Topics: Adult; Area Under Curve; Arthritis, Rheumatoid; Biological Specimen Banks; Biomarkers; Body Mass Index; Carnitine; Chromatography, High Pressure Liquid; Discriminant Analysis; Fatty Acids; Female; Humans; Least-Squares Analysis; Lipids; Lysophosphatidylcholines; Metabolomics; Middle Aged; Principal Component Analysis; ROC Curve; Tryptophan	2016
Cord Blood Metabolic Signatures of Birth Weight: A Population-Based Study. Journal of proteome research, 2018, 03-02, Volume: 17, Issue:3 Topics: Birth Weight; Carnitine; Chromatography, High Pressure Liquid; Cohort Studies; Docosahexaenoic Acids; Environmental Exposure; Europe; Female; Fetal Blood; Fetal Development; Fetus; Humans; Indoles; Infant, Newborn; Male; Mass Spectrometry; Metabolome; Particulate Matter; Phosphatidylcholines; Pregnancy; Progesterone; Prostaglandins; Reference Standards; Tryptophan; Vitamin A	2018
A Non-Targeted LC-MS Profiling Reveals Elevated Levels of Carnitine Precursors and Trimethylated Compounds in the Cord Plasma of Pre-Eclamptic Infants. Scientific reports, 2018, 10-02, Volume: 8, Issue:1 Topics: Adult; Biomarkers; Carnitine; Case-Control Studies; Chromatography, Liquid; Creatine; Cross-Sectional Studies; Female; Fetal Blood; Humans; Infant, Newborn; Metabolomics; Phosphatidylcholines; Pre-Eclampsia; Pregnancy; Principal Component Analysis; Putrescine; Pyridoxic Acid; Tandem Mass Spectrometry; Tryptophan; Urea	2018
Tryptophan 224 of the rat mitochondrial carnitine/acylcarnitine carrier is crucial for the antiport mechanism. Biochimica et biophysica acta. Bioenergetics, 2019, 09-01, Volume: 1860, Issue:9 Topics: Amino Acid Sequence; Animals; Antiporters; Aspergillus nidulans; Biological Transport; Carnitine; Carnitine Acyltransferases; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Mutation; Protein Conformation; Rats; Recombinant Proteins; Sequence Homology; Tryptophan	2019
Knockout of the non-essential gene SUGCT creates diet-linked, age-related microbiome disbalance with a diabetes-like metabolic syndrome phenotype. Cellular and molecular life sciences : CMLS, 2020, Volume: 77, Issue:17 Topics: Aging; Animals; Anti-Bacterial Agents; Bacteria; Carnitine; Coenzyme A-Transferases; Dietary Supplements; Feces; Gastrointestinal Microbiome; Humans; Kidney; Lipid Metabolism; Liver; Lysine; Metabolic Syndrome; Metabolome; Mice; Mice, Knockout; Obesity; Tryptophan	2020
Systemic and central nervous system metabolic alterations in Alzheimer's disease. Alzheimer's research & therapy, 2019, 11-28, Volume: 11, Issue:1 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Brain; Carnitine; Case-Control Studies; Energy Metabolism; Female; Humans; Male; Metabolomics; Middle Aged; Phosphorylation; tau Proteins; Tryptophan	2019
Loss of function in the Drosophila clock gene period results in altered intermediary lipid metabolism and increased susceptibility to starvation. Cellular and molecular life sciences : CMLS, 2020, Volume: 77, Issue:23 Topics: Animals; Biomarkers; Carnitine; Circadian Clocks; Circadian Rhythm; Drosophila melanogaster; Drosophila Proteins; Feeding Behavior; Lipid Metabolism; Lipids; Loss of Function Mutation; Male; Metabolome; Motor Activity; Period Circadian Proteins; Starvation; Stress, Physiological; Tryptophan	2020
Plasma metabolomics supports the use of long-duration cardiac arrest rodent model to study human disease by demonstrating similar metabolic alterations. Scientific reports, 2020, 11-12, Volume: 10, Issue:1 Topics: Animals; Biomarkers; Cardiopulmonary Resuscitation; Carnitine; Disease Models, Animal; Fatty Acids; Heart Arrest; Humans; Kynurenic Acid; Male; Metabolomics; Phospholipids; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Tryptophan	2020
Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19. Cells, 2021, 09-02, Volume: 10, Issue:9 Topics: Acute Disease; Adult; Amino Acids; Body Mass Index; Carnitine; Cohort Studies; COVID-19; Fatty Acids; Female; Humans; Kynurenine; Machine Learning; Metabolomics; Middle Aged; Prognosis; Prospective Studies; SARS-CoV-2; Severity of Illness Index; Tryptophan	2021
[Biosynthesis of reserpine-like substances in myocardium and other human and animal tissues]. Biulleten' eksperimental'noi biologii i meditsiny, 1978, Volume: 86, Issue:8 Topics: Acetates; Adult; Animals; Cell-Free System; Death, Sudden; Histidine; Humans; Liver; Microsomes, Liver; Middle Aged; Myocardium; N-Formylmethionine; Organ Specificity; Rats; Reserpine; S-Adenosylmethionine; Tryptophan; Tyrosine	1978
Cofactor and DNA interactions in EcoRI DNA methyltransferase. Fluorescence spectroscopy and phenylalanine replacement for tryptophan 183. The Journal of biological chemistry, 1992, Sep-15, Volume: 267, Issue:26 Topics: Acrylamide; Acrylamides; Base Sequence; DNA; Fluorescence Polarization; Genetic Vectors; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Tryptophan	1992
Effect of short-term administration of nitrous oxide on plasma concentrations of methionine, tryptophan, phenylalanine and S-adenosyl methionine in man. British journal of anaesthesia, 1986, Volume: 58, Issue:1 Topics: Adult; Aged; Amino Acids; Anesthesia, General; Female; Humans; Male; Methionine; Middle Aged; Nitrous Oxide; Phenylalanine; S-Adenosylmethionine; Time Factors; Tryptophan	1986
Trypsin cleavage of human cystathionine beta-synthase into an evolutionarily conserved active core: structural and functional consequences. Archives of biochemistry and biophysics, 1998, Jul-15, Volume: 355, Issue:2 Topics: Amino Acid Sequence; Binding Sites; Conserved Sequence; Cystathionine beta-Synthase; Enzyme Activation; Heme; Hot Temperature; Humans; Hydrolysis; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Protein Denaturation; Pyridoxal Phosphate; Recombinant Proteins; S-Adenosylmethionine; Solvents; Spectrometry, Fluorescence; Trypsin; Tryptophan	1998
Structural studies of the BstVI restriction-modification proteins by fluorescence spectroscopy. European journal of biochemistry, 1999, Volume: 263, Issue:1 Topics: Deoxyribonucleases, Type II Site-Specific; Geobacillus stearothermophilus; Iodides; Magnesium; Protein Conformation; S-Adenosylmethionine; Site-Specific DNA-Methyltransferase (Adenine-Specific); Spectrometry, Fluorescence; Temperature; Tryptophan	1999
Scavengers protection of cells against ALA-based photodynamic therapy-induced damage. Lasers in medical science, 2002, Volume: 17, Issue:4 Topics: Aminolevulinic Acid; Animals; Antioxidants; Cell Line; Cell Survival; Free Radical Scavengers; Glutathione; Mammary Neoplasms, Experimental; Methionine; Mice; Photochemotherapy; Radiation Injuries, Experimental; Radiation-Protective Agents; Radiation-Sensitizing Agents; S-Adenosylmethionine; Tryptophan	2002
Probing a rate-limiting step by mutational perturbation of AdoMet binding in the HhaI methyltransferase. Nucleic acids research, 2005, Volume: 33, Issue:1 Topics: Binding Sites; DNA; DNA-Cytosine Methylases; Kinetics; Mutagenesis, Site-Directed; Protein Binding; S-Adenosylmethionine; Tryptophan	2005
Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults. V. Complementary and alternative medicine treatments. Journal of affective disorders, 2009, Volume: 117 Suppl 1 Topics: Acupuncture Therapy; Adult; Antidepressive Agents; Complementary Therapies; Dehydroepiandrosterone; Depressive Disorder, Major; Dietary Supplements; Exercise Therapy; Fatty Acids, Omega-3; Herbal Medicine; Humans; Hypericum; Phototherapy; Phytotherapy; S-Adenosylmethionine; Sleep Deprivation; Tryptophan; Yoga	2009
Radical-mediated enzymatic carbon chain fragmentation-recombination. Nature chemical biology, 2011, Volume: 7, Issue:3 Topics: Binding Sites; Carbon; Catalysis; Chromatography, High Pressure Liquid; Free Radicals; Indoles; Peptides; S-Adenosylmethionine; Substrate Specificity; Thiazoles; Time Factors; Tryptophan	2011
Enzymology: Radical break-up, blissful make-up. Nature chemical biology, 2011, Volume: 7, Issue:3 Topics: Anti-Bacterial Agents; Catalysis; Enzyme Activation; Enzymes and Coenzymes; Free Radicals; Models, Chemical; S-Adenosylmethionine; Thiazoles; Tryptophan	2011
Characterization of NocL involved in thiopeptide nocathiacin I biosynthesis: a [4Fe-4S] cluster and the catalysis of a radical S-adenosylmethionine enzyme. The Journal of biological chemistry, 2011, Jun-17, Volume: 286, Issue:24 Topics: Amino Acid Sequence; Catalysis; DNA Mutational Analysis; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Intercellular Signaling Peptides and Proteins; Iron-Sulfur Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Tryptophan	2011
Dietary supplement drug therapies for depression. Journal of psychosocial nursing and mental health services, 2012, Volume: 50, Issue:6 Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Depressive Disorder; Dietary Supplements; Drug Approval; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Fatty Acids, Omega-3; Humans; Inositol; S-Adenosylmethionine; Self Medication; Tetrahydrofolates; Treatment Outcome; Tryptophan; United States; United States Food and Drug Administration	2012
Thiostrepton tryptophan methyltransferase expands the chemistry of radical SAM enzymes. Nature chemical biology, 2012, Volume: 8, Issue:12 Topics: Cloning, Molecular; Dithionite; Dithiothreitol; Escherichia coli; Methyltransferases; Recombinant Proteins; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfhydryl Reagents; Thiostrepton; Tryptophan; Vitamin B 12	2012
Protein l-isoaspartyl-O-methyltransferase of Vibrio cholerae: interaction with cofactors and effect of osmolytes on unfolding. Biochimie, 2013, Volume: 95, Issue:4 Topics: Coenzymes; Glycerol; Guanidine; Methylamines; Models, Molecular; Osmosis; Protein Conformation; Protein D-Aspartate-L-Isoaspartate Methyltransferase; Protein Unfolding; S-Adenosylmethionine; Solvents; Stress, Physiological; Thermodynamics; Tryptophan; Vibrio cholerae	2013
The mechanisms of radical SAM/cobalamin methylations: an evolving working hypothesis. Chembiochem : a European journal of chemical biology, 2013, Apr-15, Volume: 14, Issue:6 Topics: Anti-Bacterial Agents; Methylation; Methyltransferases; S-Adenosylmethionine; Streptomyces; Thiostrepton; Tryptophan; Vitamin B 12	2013
Ergothioneine biosynthetic methyltransferase EgtD reveals the structural basis of aromatic amino acid betaine biosynthesis. Chembiochem : a European journal of chemical biology, 2015, Jan-02, Volume: 16, Issue:1 Topics: Amino Acid Sequence; Ascomycota; Basidiomycota; Betaine; Catalytic Domain; Crystallography, X-Ray; Ergothioneine; Escherichia coli; Fungal Proteins; Gene Expression; Histidine; Methyltransferases; Models, Molecular; Molecular Sequence Data; Mutation; Recombinant Proteins; S-Adenosylhomocysteine; S-Adenosylmethionine; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan	2015
Identification of (2S,3S)-β-Methyltryptophan as the Real Biosynthetic Intermediate of Antitumor Agent Streptonigrin. Scientific reports, 2016, Feb-05, Volume: 6 Topics: Antineoplastic Agents; Bacterial Proteins; Chromatography, High Pressure Liquid; Escherichia coli; Mass Spectrometry; Methyltransferases; Plasmids; S-Adenosylmethionine; Stereoisomerism; Streptomyces; Streptonigrin; Tryptophan	2016
BIOCHEMISTRY. A radically unexpected mechanism. Science (New York, N.Y.), 2016, Mar-18, Volume: 351, Issue:6279 Topics: Carbon-Carbon Lyases; Indoles; S-Adenosylmethionine; Streptomyces; Tryptophan; Tryptophanase	2016
Fine-tuning of a radical-based reaction by radical S-adenosyl-L-methionine tryptophan lyase. Science (New York, N.Y.), 2016, Mar-18, Volume: 351, Issue:6279 Topics: Carbon-Carbon Lyases; Catalytic Domain; Electron Spin Resonance Spectroscopy; Indoles; S-Adenosylmethionine; Streptomyces; Tryptophan; Tryptophanase	2016
Mass Spectrometry Based Metabolomics Comparison of Liver Grafts from Donors after Circulatory Death (DCD) and Donors after Brain Death (DBD) Used in Human Orthotopic Liver Transplantation. PloS one, 2016, Volume: 11, Issue:11 Topics: Adult; Biomarkers; Brain Death; Cyclotrons; Female; Glucose; Glutathione; Graft Survival; Humans; Kynurenine; Liver; Liver Transplantation; Male; Metabolomics; Middle Aged; Principal Component Analysis; S-Adenosylmethionine; Shock; Spectroscopy, Fourier Transform Infrared; Tissue Donors; Tryptophan; Warm Ischemia	2016
Tryptophan Lyase (NosL): A Cornucopia of 5'-Deoxyadenosyl Radical Mediated Transformations. Journal of the American Chemical Society, 2016, 12-21, Volume: 138, Issue:50 Topics: Biocatalysis; Catalytic Domain; Free Radicals; Lyases; Models, Molecular; S-Adenosylmethionine; Tryptophan	2016
Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci. ACS chemical biology, 2017, 04-21, Volume: 12, Issue:4 Topics: Amino Acid Sequence; Electron Spin Resonance Spectroscopy; Enzymes; Lysine; Peptides; S-Adenosylmethionine; Sequence Homology, Amino Acid; Spectrophotometry, Ultraviolet; Streptococcus agalactiae; Streptococcus suis; Tryptophan	2017
Efficient methylation of C2 in l-tryptophan by the cobalamin-dependent radical The Journal of biological chemistry, 2017, 09-15, Volume: 292, Issue:37 Topics: Bacterial Proteins; Biocatalysis; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Enzyme Stability; Kinetics; Methylation; Methyltransferases; Molecular Structure; Recombinant Fusion Proteins; Recombinant Proteins; S-Adenosylmethionine; Spectrophotometry; Staphylococcus; Substrate Specificity; Thiostrepton; Tryptophan; Vitamin B 12	2017
TsrM as a Model for Purifying and Characterizing Cobalamin-Dependent Radical S-Adenosylmethionine Methylases. Methods in enzymology, 2017, Volume: 595 Topics: Bacterial Proteins; Biocatalysis; Coenzymes; Cysteine; Escherichia coli; Iron-Sulfur Proteins; Methylation; Methyltransferases; Protein Binding; S-Adenosylmethionine; Small Ubiquitin-Related Modifier Proteins; Tryptophan; Vitamin B 12	2017
Mechanistic Studies on the Radical SAM Enzyme Tryptophan Lyase (NosL). Methods in enzymology, 2018, Volume: 606 Topics: Biocatalysis; Carbon-Carbon Lyases; Cloning, Molecular; Crystallography, X-Ray; Enzyme Assays; Molecular Structure; Recombinant Proteins; S-Adenosylmethionine; Thiazoles; Tryptophan	2018
Reductive Cleavage of Sulfoxide and Sulfone by Two Radical S-Adenosyl-l-methionine Enzymes. Biochemistry, 2019, 01-08, Volume: 58, Issue:1 Topics: Carbon-Carbon Lyases; Methyltransferases; S-Adenosylmethionine; Safrole; Sulfones; Tryptophan	2019
Understanding the role of electron donors in the reaction catalyzed by Tsrm, a cobalamin-dependent radical S-adenosylmethionine methylase. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2019, Volume: 24, Issue:6 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Dithiothreitol; Escherichia coli; Hydroxocobalamin; Iron-Sulfur Proteins; Methylation; Oxidation-Reduction; S-Adenosylmethionine; Tryptophan; Vitamin B 12	2019
Nano-second protein dynamics of key residue at Position 38 in catechol-O-methyltransferase system: a time-resolved fluorescence study. Journal of biochemistry, 2020, Oct-01, Volume: 168, Issue:4 Topics: Catalytic Domain; Catechol O-Methyltransferase; Catechols; Fluorescence; Humans; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; S-Adenosylmethionine; Structure-Activity Relationship; Tryptophan	2020
Structural basis for non-radical catalysis by TsrM, a radical SAM methylase. Nature chemical biology, 2021, Volume: 17, Issue:4 Topics: Arginine; Catalysis; Coenzymes; Iron-Sulfur Proteins; Methylation; Methyltransferases; S-Adenosylmethionine; Streptomycetaceae; Thiostrepton; Tryptophan; Vitamin B 12; X-Ray Diffraction	2021
Trapping a cross-linked lysine-tryptophan radical in the catalytic cycle of the radical SAM enzyme SuiB. Proceedings of the National Academy of Sciences of the United States of America, 2021, 05-25, Volume: 118, Issue:21 Topics: Bacterial Proteins; Binding Sites; Catalysis; Cloning, Molecular; Electron Spin Resonance Spectroscopy; Escherichia coli; Gene Expression; Genetic Vectors; Iron-Sulfur Proteins; Kinetics; Lysine; Models, Molecular; Oxidation-Reduction; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Ribosomal Proteins; S-Adenosylmethionine; Streptococcus; Substrate Specificity; Thermodynamics; Tryptophan	2021
Exploring the Biosynthetic Potential of TsrM, a B Chemistry (Weinheim an der Bergstrasse, Germany), 2022, Jun-01, Volume: 28, Issue:31 Topics: Methylation; Methyltransferases; S-Adenosylmethionine; Tryptophan; Vitamin B 12	2022
L-tyrosine-bound ThiH structure reveals C-C bond break differences within radical SAM aromatic amino acid lyases. Nature communications, 2022, 04-27, Volume: 13, Issue:1 Topics: Catalysis; Lyases; S-Adenosylmethionine; Tryptophan; Tyrosine	2022
Bioinformatic Atlas of Radical SAM Enzyme-Modified RiPP Natural Products Reveals an Isoleucine-Tryptophan Crosslink. Journal of the American Chemical Society, 2022, 10-05, Volume: 144, Issue:39 Topics: Amidines; Biological Products; Computational Biology; Iron; Isoleucine; Peptides; Protein Processing, Post-Translational; S-Adenosylmethionine; Sulfur; Tryptophan	2022