tryptophan has been researched along with pyridoxal phosphate in 188 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 146 (77.66) | 18.7374 |
| 1990's | 20 (10.64) | 18.2507 |
| 2000's | 5 (2.66) | 29.6817 |
| 2010's | 14 (7.45) | 24.3611 |
| 2020's | 3 (1.60) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Lees, GJ | 1 |
| Araya, A; Labouesse, J; Litvak, S | 1 |
| Seed, JR; Stibbs, HH | 1 |
| Bapurao, S; Krishnaswamy, K | 1 |
| Rose, DP | 1 |
| Guseĭnova, RS | 1 |
| Brown, RR; Wolf, H | 1 |
| Borzani, M; Giovannini, M; Motta, G; Riva, E | 1 |
| Augusto, O; Cilento, G | 1 |
| Bhargava, A; Chauhan, YS; Garg, GK; Rathore, VS | 1 |
| Arrio-Dupont, M | 1 |
| Brown, RR; Leklem, JE; Linkswiler, HM; Rose, DP | 2 |
| Benson, EM; Johnson, A; Miller, LT; Woodring, MJ | 1 |
| Barlow, GB; Wilkinson, AW | 1 |
| Cioni, P; Onuffer, JJ; Strambini, GB | 1 |
| Cioni, P; Mozzarelli, A; Peracchi, A; Strambini, GB | 1 |
| Bender, DA; Njagi, EN; Okelo, GB | 1 |
| Amino, N; Asari, S; Fushimi, R; Hayashi, S; Kimura, S; Miyai, K; Yamaguchi, Y | 1 |
| Fujimoto, H; Haneda, M; Nakatsuka, M; Nisimoto, Y; Nomura, S; Ohta, T; Shibata, Y; Takeuchi, F; Tamai, T; Tsubouchi, R | 1 |
| Gollnick, P; Phillips, RS | 1 |
| Leklem, JE | 2 |
| Kawata, Y; Mizobata, T; Tani, S; Tokushige, M; Tsujimoto, N | 1 |
| Gietzen, DW; Grier, RE; Sampson, DA; Schaeffer, MC; Skala, JH | 1 |
| Kiick, DM; Phillips, RS | 1 |
| Asada, Y; Sawa, Y; Soda, K; Tanizawa, K | 1 |
| Balasubramanian, KA; Baskaran, S | 1 |
| Parsot, C | 1 |
| Kanoh, T; Mizoguchi, I; Suzuki, T | 1 |
| Fisher, H; Lee, NS; Muhs, G; Reynolds, RD; Wagner, GC | 1 |
| Jirgensone, S; Jirgensons, J; Jurika, E; Rudzite, V; Sileniece, G; Zirne, R | 1 |
| Datta, P; Goss, TJ; Omnaas, JR; Patil, RV | 1 |
| Soda, K; Yoshimura, T | 1 |
| Bruinse, HW; Louwerse, ES; Schrijver, J; Thissen, JT; van den Berg, H | 1 |
| Birt, DF; Cohen, SM; Hasegawa, R; Julius, AD; St John, M | 1 |
| Bhagwat, AS; Verma, NC | 1 |
| Lee, CM; Leklem, JE | 1 |
| Leklem, JE; Miller, LT; Shultz, TD | 1 |
| Gonnard, P | 1 |
| Cleary, RE; Li, TK; Lumeng, L | 1 |
| Konyshev, VA | 1 |
| Murali, DK; Radhakrishnan, AN | 1 |
| Curzon, G; Green, AR | 1 |
| Matchett, WH | 2 |
| Moore, TC; Shaner, CA | 1 |
| Abdel-Daim, MH; Abdel-Tawab, GA; Amer, MS | 3 |
| Manning, B; Mason, M | 1 |
| Steinberg, IZ | 1 |
| Cole, KW; Gaertner, FH; Welch, GR | 1 |
| Reinken, L | 1 |
| Hayasaki, N; Nakashima, S; Oura, H | 1 |
| Ford, J; Mason, M; Wu, HL | 1 |
| Geller, E; Wetterberg, L; Yuwiler, A | 1 |
| Berg, CP; Loh, HH | 1 |
| Eiduson, S; Geller, E; Yuwiler, A | 1 |
| Puzyńska, L | 1 |
| Badawy, AA | 1 |
| Kumagai, H; Nakazawa, H; Yamada, H | 1 |
| Diven, WF; Grever, MR; Meneely, RL; Neary, JT | 1 |
| Haskell, BE; Snell, EE | 1 |
| Goldberg, ME; London, J | 1 |
| Kagamiyama, H; Matsubara, H; Snell, EE; Wada, H | 1 |
| Kagamiyama, H; Matsubara, H; Snell, EE | 1 |
| Snell, EE; Watanabe, T | 1 |
| Aloj, S; Bruni, CB; Edelhoch, H; Rechler, MM | 1 |
| Gambhir, KK; McMenamy, RH | 1 |
| Emerson, PM; Mason, DY | 1 |
| Honikel, KO; Madsen, NB | 1 |
| Daniel, LJ; Gray, LF | 1 |
| Crawford, IP; Hatanaka, M; Miles, EW | 1 |
| Goldberg, ME; Stryer, L; York, S | 1 |
| Abe, M; Kotake, Y; Murakami, E | 1 |
| Fukui, S; Nakai, Y; Ohishi, N; Shimizu, S | 1 |
| Crawford, IP; Hathaway, GM; Kida, S | 1 |
| Delmer, DP; Mills, S | 1 |
| Crawford, IP | 1 |
| Fukui, S; Masugi, F; Nakai, Y; Ohishi, N | 1 |
| Creighton, TE | 1 |
| Duhault, J; Gonnard, P; Nguyen-Philippon, C | 1 |
| Snell, EE | 2 |
| Crawford, IP; Maurer, R | 1 |
| DeMoss, RD; Hoch, SO | 1 |
| Abdel-Daim, MH; Abdel-Tawab, GA; el-Sawy, MF; el-Sewedy, SM | 1 |
| Bruckner, FE; Chamberlain, MA; Lakatos, C; Smith, HG | 1 |
| Angelino, N; Korytnyk, W; Lachmann, B | 1 |
| Chabner, BA; DeVita, VT; Livingston, DM; Oliverio, VT | 2 |
| Cowgill, RW; Jones, DC | 1 |
| Cornish, HH | 1 |
| Altshuler, CH; Hollister, C; Klieger, JA; Krakow, G | 1 |
| Hamfelt, A; Wetterberg, L | 2 |
| De Ropp, RS; Furst, A | 1 |
| Arakawa, T; Higashi, O; Ohara, K; Tamura, T; Tanno, K | 1 |
| Creighton, TE; Yanofsky, C | 1 |
| Korbitz, BC | 1 |
| Abdel-Tawab, GA; el-Shafei, AK; el-Zoghby, SM; Kelada, FS | 1 |
| Anke, A; Schmidt, E; Wolfram, G | 1 |
| Brown, RR; Madsen, PO; Wolf, H | 1 |
| Arakawa, T; Nakagawa, H; Tada, K; Yokoyama, Y; Yoshida, T | 1 |
| Körner, WF; Nowak, H | 1 |
| Cavill, IA; Jacobs, A | 1 |
| DeMoss, RD; Gopinathan, KP | 1 |
| DeMoss, RD; O'Neil, SR | 1 |
| Hahn, L; Hamfelt, A | 1 |
| Sukanya, NK; Vaidyanathan, CS | 1 |
| Da Vanzo, JP; Kang, L | 1 |
| Hagberg, B; Hamfelt, A; Hansson, O | 1 |
| Hagberg, B; Hansson, O | 1 |
| DeMoss, RD; Hoch, JA | 1 |
| Heeley, AF; Roberts, GE | 1 |
| Marino, G; Scardi, V; Zito, R | 1 |
| Linkswiler, H | 1 |
| Constantsas, NS; Knox, WE | 1 |
| Ikawa, M | 1 |
| Oliner, L; Schulz, AR | 1 |
| Martinez-Carrion, M; Tiemeier, D | 1 |
| Hamfelt, A | 1 |
| Allenmark, S; Hallert, C; Larsson-Cohn, U; Sedvall, G | 1 |
| Bonjour, JP | 1 |
| Bender, DA; Tagoe, CE; Vale, JA | 1 |
| Shideler, CE | 1 |
| Cohen, LA; Miles, EW; Phillips, RS | 1 |
| Davis, RE; Wilson, RG | 1 |
| Bartholmes, P | 1 |
| Botteri, A; Hamfelt, A; Söderhjelm, L | 1 |
| Borri Voltattorni, C; Dominici, P; Murgia, SM; Pasqua, A; Poletti, A | 1 |
| Ribeiro, P; Webb, RA | 1 |
| Bender, DA; Totoe, L | 1 |
| Gracy, RW; Lu, HS; Talent, JM | 1 |
| Iinuma, K; Nishijima, Y; Tokushige, M; Yamamoto, M | 1 |
| Bender, DA; Wynick, D | 1 |
| Arend, RA; Brown, RR; Walter, S; Wolf, H | 1 |
| Rumsby, PC; Shepherd, DM | 1 |
| Esaki, N; Kishimoto, K; Manning, JM; Soda, K; Sugio, S; Yoshimura, T | 1 |
| Belikov, VM; Dementieva, IS; Faleev, NG; Gogoleva, OI; Zakomirdina, LN | 1 |
| Eddy, C; Gu, W; Jensen, RA; Zhao, G | 1 |
| Ahmed, SA; Banik, U; Miles, EW; Parris, KD; Ruvinov, SB; Sackett, DL; Yang, XJ | 1 |
| Hayashi, H; Hirotsu, K; Kagamiyama, H; Kuramitsu, S; Metzler, CM; Metzler, DE; Miyahara, I; Mollova, ET; Scott, RD; Yano, T | 1 |
| Cook, PF; McClure, GD | 1 |
| Petrich, JW; Rich, RL; Smirnov, AV | 1 |
| Bitsch, R | 1 |
| Douce, R; Droux, M; Job, D; Rolland, N; Ruffet, ML | 1 |
| Manning, JM; Martinez del Pozo, A; Petsko, G; Ringe, D; Soda, K; van Ophem, PW | 1 |
| Ahmed, SA; Jhee, KH; McPhie, P; Miles, EW; Rowlett, R; Yang, LH | 1 |
| Kery, V; Kraus, JP; Poneleit, L | 1 |
| Girard, CL; Matte, JJ; Sève, B | 1 |
| Benci, S; Bettati, S; Campanini, B; Gratton, E; Hazlett, TL; Mozzarelli, A; Schianchi, G; Vaccari, S | 1 |
| BAGLIONI, C; FASELLA, P; SILIPRANDI, N; TURANO, C | 1 |
| GEYER, H | 1 |
| BARCHAS, J; LOVENBERG, W; UDENFRIEND, S; WEISSBACH, H | 1 |
| CREPALDI, G; PARPAJOLA, A | 1 |
| HARRINGTON, H; SAKAMI, W | 1 |
| MAZELIS, M; RIDDLE, VM | 1 |
| BONOMI, U; TENCONI, LT | 1 |
| NAIR, PM; VAIDYANATHAN, CS | 1 |
| NEWTON, WA; SNELL, EE | 1 |
| CRAWFORD, IP; ITO, J | 1 |
| ITO, H | 1 |
| CARSIOTIS, M; SUSKIND, SR | 1 |
| MORINO, Y; NEWTON, WA; SNELL, EE | 1 |
| Erglis, A; Fuchs, D; Jegere, S; Jurika, E; Kalnins, U; Rudzite, V; Silava, A; Trusinskis, K | 1 |
| Goody, RS; Holtermann, G; Miles, EW; Phillips, RS | 1 |
| Fukuwatari, T; Shibata, K; Wada, H | 1 |
| GUNSALUS, IC; UMBREIT, WW; WOOD, WA | 1 |
| Ali, V; Bhakuni, V; Kumar, A; Mishra, V; Nozaki, T; Zhang, KY | 1 |
| Dolina, S; Malitsky, S; Margalit, D; Pressman, E; Rabinkov, A | 1 |
| Chory, J; Dai, X; Guo, Y; Ljung, K; Noel, JP; Novák, O; Zhao, Y; Zheng, Z | 1 |
| Chi, YY; Coats, B; da Silva, VR; Garrett, TJ; Gregory, JF; Lamers, Y; Midttun, Ø; Muller, KE; Percival, SS; Quinlivan, EP; Ralat, MA; Rios-Avila, L; Shankar, MN; Stacpoole, PW; Ueland, PM | 1 |
| Becker, K; Hort, W; Jortzik, E; Lang, S; Lochnit, G; Mayser, PA; Netsch, A; Preuss, J; Rahlfs, S | 1 |
| Eussen, SJ; Midttun, Ø; Nygård, O; Pedersen, ER; Ueland, PM; Ulvik, A | 1 |
| Eussen, SJ; Hustad, S; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Brody, LC; Brosnan, JT; Brosnan, ME; Deac, OM; Fan, R; Gibney, ER; Laird, E; Midttun, Ø; Mills, JL; Molloy, AM; Shane, B; Ueland, PM; Wang, Y | 1 |
| Oxenkrug, GF | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Ralat, M; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Almog, O; Gdaelvsky, G; Goldgur, Y; Green, K; Kogan, A; Lotan, O; Parola, AH; Qasim, N | 1 |
| Brody, LC; Deac, OM; Fan, R; Gardiner, CM; Lu, Z; McCann, A; Meyer, K; Midttun, Ø; Mills, JL; Molloy, AM; Quinn, L; Shane, B; Ueland, PM | 1 |
| McCann, A; Meyer, K; Midttun, Ø; Nygård, O; Tell, G; Ueland, PM; Ulvik, A | 1 |
| Bellet, MM; Cellini, B; Costantini, C; Dindo, M; Renga, G; Romani, L; Zelante, T | 1 |
| Barona-Gómez, F; Hung, DT; Jedrzejczak, R; Joachimiak, A; Maltseva, N; Michalska, K; Rosas-Becerra, LR; Selem-Mojica, N; Wellington, S | 1 |
18 review(s) available for tryptophan and pyridoxal phosphate
| Article | Year |
|---|---|
The interactions between vitamin B6 and hormones.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Biogenic Amines; Brain; Contraceptives, Oral, Hormonal; Estradiol Congeners; Estrogens; Female; Gonadotropins; Growth Hormone; Hormones; Humans; Pituitary Hormones; Pregnancy; Prolactin; Pyridoxal Phosphate; Pyridoxine; Thyroid Hormones; Thyrotropin; Tryptophan; Vitamin B 6 Deficiency | 1978 |
Vitamin B-6: a status report.
Topics: Erythrocytes; Humans; Liver; Methionine; Nutrition Assessment; Nutritional Status; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Transaminases; Tryptophan | 1990 |
Evaluation of vitamin B-6 status and function of rats fed excess pyridoxine.
Topics: Animals; Body Weight; Brain Chemistry; Digestive System; Energy Intake; Erythrocytes; Kidney; Liver; Nutritional Requirements; Nutritional Status; Phosphorylases; Pyridoxal Phosphate; Pyridoxine; Rats; Transaminases; Tryptophan | 1989 |
Vitamin B-6 requirement and oral contraceptive use--a concern?
Topics: Adult; Contraceptives, Oral; Drug Interactions; Female; Humans; Middle Aged; Nutritional Requirements; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1986 |
[Current data on the lateral biochemical effects of dopa].
Topics: Aminobutyrates; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Dopa Decarboxylase; Melatonin; Metabolism; Methylation; Polyribosomes; Protein Biosynthesis; Pyridoxal Phosphate; S-Adenosylmethionine; Stimulation, Chemical; Tryptophan; Tyrosine 3-Monooxygenase | 1974 |
[Binding and transport of substances by serum albumin].
Topics: Aflatoxins; Animals; Antidotes; Bilirubin; Biological Transport; Coloring Agents; Digitoxin; DNA; Fatty Acids, Nonesterified; Fluoresceins; Heparin; Histidine; Humans; Hydrocortisone; Ligands; Penicillins; Phenols; Protein Binding; Pyridoxal Phosphate; Riboflavin; Serum Albumin; Sulfanilamides; Testosterone; Threonine; Thyroxine-Binding Proteins; Tryptophan | 1973 |
Long-range nonradiative transfer of electronic excitation energy in proteins and polypeptides.
Topics: Adrenocorticotropic Hormone; Catalase; Chemical Phenomena; Chemistry, Physical; Coloring Agents; Copper; Dipeptides; Energy Transfer; Fluorescence; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Hemoglobins; Indoles; Insulin; L-Lactate Dehydrogenase; Mathematics; Monoiodotyrosine; Myoglobin; NAD; Parathyroid Hormone; Peptides; Phenols; Phenylalanine; Phosphoric Acids; Picolines; Plant Proteins; Proteins; Pyridoxal Phosphate; Thyroxine; Transferrin; Tryptophan; Tyrosine | 1971 |
[Scope and effect of vitamin B6 in newborn infants and children].
Topics: Amino Acids; Anemia, Hypochromic; Aspartate Aminotransferases; Brain; Coenzymes; Drug Antagonism; Female; Gestational Age; Humans; Hydantoins; Infant, Newborn; Iron; Isoniazid; Maternal-Fetal Exchange; Nutritional Physiological Phenomena; Nutritional Requirements; Penicillamine; Phosphotransferases; Pregnancy; Pyridoxal Phosphate; Pyridoxine; Seizures; Succinimides; Tryptophan; Vitamin B Deficiency; Xanthurenates | 1974 |
Oral contraceptive agents and vitamins.
Topics: Anemia, Macrocytic; Animals; Contraceptives, Oral; Estrogens; Female; Folic Acid; Glutamates; Humans; Intestinal Absorption; Metabolic Diseases; Nutrition Disorders; Pyridoxal Phosphate; Pyridoxine; Rats; Steroids; Sulfuric Acids; Tryptophan; Tryptophan Oxygenase; Vitamin B 6 Deficiency; Vitamins | 1972 |
Xanthurenic acid and xanthurenic acid-8-methyl ether.
Topics: Animals; Blood Glucose; Ethers; Insulin; Kynurenine; Pyridoxal Phosphate; Time Factors; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1968 |
[Tryptophan synthetase of . coli. Recent studies on the beta-2 subunits].
Topics: Electrophoresis; Escherichia coli; Genes; Genetics, Microbial; Hydro-Lyases; Mutation; Pyridoxal Phosphate; Serine; Tryptophan | 1969 |
Analogs of pyridoxal or pyridoxal phosphate: relation of structure to binding with apoenzymes and to catalytic activity.
Topics: Apoproteins; Arginine; Aspartic Acid; Carboxy-Lyases; Catalysis; Chemical Phenomena; Chemistry; Coenzymes; Hydrolases; L-Serine Dehydratase; Models, Biological; Organophosphorus Compounds; Phosphorylases; Picolines; Protein Binding; Protein Conformation; Pyridines; Pyridoxal; Pyridoxal Phosphate; Pyridoxamine; Pyridoxine; Pyruvates; Structure-Activity Relationship; Transaminases; Tryptophan | 1970 |
Vitamins and alcoholism. III. Vitamin B6.
Topics: Alcoholism; Anemia, Sideroblastic; Animals; Aspartate Aminotransferases; False Positive Reactions; Female; Humans; Intestinal Absorption; Liver; Liver Diseases, Alcoholic; Male; Peripheral Nervous System Diseases; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1980 |
Vitamin B6: an overview.
Topics: Adult; Animals; Chemical Phenomena; Chemistry; Child; Female; Humans; Infant; Metabolism, Inborn Errors; Pyridoxal Phosphate; Pyridoxine; Rats; Transaminases; Tryptophan; Vitamin B 6 Deficiency | 1983 |
Clinical chemistry of vitamin B6.
Topics: Animals; Biological Assay; Biological Availability; Biological Transport; Chemical Phenomena; Chemistry; Contraceptives, Oral; Female; Humans; Infections; Intestinal Absorption; Kynurenine; Lactation; Liver; Models, Biological; Nutritional Requirements; Oxidation-Reduction; Phosphorylation; Pregnancy; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Radioimmunoassay; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1983 |
Vitamin B6.
Topics: Humans; Nutritional Status; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan; Vitamin B 6 Deficiency | 1993 |
AMINO ACID METABOLISM.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea | 1963 |
Pyridoxal 5'-Phosphate-Dependent Enzymes at the Crossroads of Host-Microbe Tryptophan Metabolism.
Topics: Animals; Bacteria; Host-Pathogen Interactions; Humans; Mammals; Pyridoxal Phosphate; Tryptophan; Vitamin B 6 | 2020 |
4 trial(s) available for tryptophan and pyridoxal phosphate
| Article | Year |
|---|---|
Vitamin B6 requirements of women using oral contraceptives.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Cystathionine; Female; Humans; Methionine; Nutritional Requirements; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan; Vitamin B 6 Deficiency | 1975 |
Epilepsy as a pyridoxine-dependent condition: quantified urinary biomarkers for status evaluation and monitoring antiepileptic treatment.
Topics: Adolescent; Anticonvulsants; Biomarkers; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Tryptophan | 2012 |
Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptives o
Topics: Adult; Biomarkers; Carbon; Contraceptives, Oral, Hormonal; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Metabolome; Pyridoxal Phosphate; Tryptophan; United States; Vitamin B 6; Vitamin B 6 Deficiency | 2015 |
Tryptophan catabolites as metabolic markers of vitamin B-6 status evaluated in cohorts of healthy adults and cardiovascular patients.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Cohort Studies; Cross-Sectional Studies; Female; Humans; Kynurenine; Male; Middle Aged; Pyridoxal Phosphate; Tryptophan; Vitamin B 6 | 2020 |
166 other study(ies) available for tryptophan and pyridoxal phosphate
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Functional significance of aromatic amino acid: aromatic keto acid aminotransferases in rat brain and liver: competition for tryptophan between aminotransferases and tryptophan hydroxylase in vitro.
Topics: Animals; Biopterins; Brain; Hydroxy Acids; Keto Acids; Ketoglutaric Acids; Liver; Male; Mesencephalon; Mixed Function Oxygenases; Phenylpyruvic Acids; Pyridoxal Phosphate; Rats; Transaminases; Tryptophan; Tryptophan Hydroxylase; Tyrosine Transaminase | 1977 |
Primer tRNATrp enhances the inhibition of avian myeloblastosis virus reverse transcriptase by pyridoxal-5'-phosphate.
Topics: Avian Leukosis Virus; Avian Myeloblastosis Virus; Enzyme Activation; Kinetics; Pyridoxal Phosphate; RNA-Directed DNA Polymerase; RNA, Transfer; Tryptophan | 1979 |
Further studies on the metabolism of tryptophan in Trypanosoma brucei gambiense: cofactors, inhibitors, and end-products.
Topics: Acetates; Carbon Radioisotopes; Chromatography; Enzyme Inhibitors; Indoles; Ketoglutaric Acids; Lactates; NAD; Pyridoxal Phosphate; Trypanosoma brucei gambiense; Tryptophan | 1975 |
Vitamin B6 nutritional status of pellagrins and their leucine tolerance.
Topics: Adult; Drug Tolerance; Humans; Leucine; Middle Aged; NAD; Nutritional Requirements; Pellagra; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1978 |
[Tryptophan metabolic indices in allergic dermatoses].
Topics: Chronic Disease; Dermatitis, Atopic; Female; Humans; Kynurenic Acid; Kynurenine; Male; Prurigo; Pyridoxal Phosphate; Tryptophan; Urticaria; Xanthurenates | 1979 |
Tryptophan metabolism in bladder cancer patients from Copenhagen.
Topics: Denmark; Humans; Kynurenine; Male; Pyridoxal Phosphate; Pyridoxic Acid; Tryptophan; Urinary Bladder Neoplasms | 1979 |
[Therapeutic effectiveness of pyridoxine pyrrolidonecarboxylate in febrile convulsions in children].
Topics: Ammonia; Child, Preschool; Drug Evaluation; Female; Humans; Infant; Isonicotinic Acids; Male; Pyridoxal Phosphate; Pyridoxic Acid; Pyrrolidinones; Seizures; Seizures, Febrile; Tryptophan; Vitamin B 6 Deficiency | 1977 |
Conversion of tryptophan to indolacetamide. Evidence for an electronically excited intermediate.
Topics: Chemical Phenomena; Chemistry; Horseradish Peroxidase; Indoleacetic Acids; Kinetics; Luminescent Measurements; Manganese; Peroxidases; Pyridoxal Phosphate; Spectrum Analysis; Tryptophan | 1977 |
Detection of an indole oxidizing system in maize leaves.
Topics: Chelating Agents; Copper; Indoles; Oxidation-Reduction; Oxygenases; Pyridoxal Phosphate; Serine; Tryptophan; Zea mays | 1978 |
Fluorescence of aromatic amino acids in a pyridoxal phosphate enzyme: aspartate aminotransferase.
Topics: Animals; Aspartate Aminotransferases; Cytosol; Energy Transfer; Kinetics; Myocardium; Protein Conformation; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Swine; Tryptophan | 1978 |
Effect of oral contraceptives and pyridoxine on the metabolism of vitamin B6 and on plasma tryptophan and alpha-amino nitrogen.
Topics: Adult; Alanine Transaminase; Amino Acids; Aspartate Aminotransferases; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Erythrocytes; Female; Hemoglobins; Humans; Nitrogen; Nutritional Requirements; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1975 |
Plasma pyridoxal phosphate levels and tryptophan metabolism in children with burns and scalds.
Topics: Burns; Child; Child, Preschool; Humans; Kynurenic Acid; Kynurenine; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Xanthurenates | 1975 |
Effects of oral contraceptives on tryptophan metabolism and vitamin B6 requirements in women.
Topics: Adult; Contraceptives, Oral; Cystathionine; Female; Humans; Kynurenine; Methionine; Pyridoxal Phosphate; Pyridoxine; Sex Factors; Tryptophan; Vitamin B 6 Deficiency | 1975 |
Characterization of tryptophan phosphorescence of aspartate aminotransferase from Escherichia coli.
Topics: Apoenzymes; Aspartate Aminotransferases; Escherichia coli; Kinetics; Luminescent Measurements; Pyridoxal Phosphate; Pyridoxamine; Thermodynamics; Tryptophan | 1992 |
Characterization of tryptophan and coenzyme luminescence in tryptophan synthase from Salmonella typhimurium.
Topics: Binding Sites; Luminescent Measurements; Macromolecular Substances; Protein Conformation; Pyridoxal Phosphate; Salmonella typhimurium; Schiff Bases; Spectrometry, Fluorescence; Thermodynamics; Time Factors; Tryptophan; Tryptophan Synthase | 1992 |
Tryptophan metabolism and vitamin B6 nutritional status in patients with schistosomiasis mansoni and in infected mice.
Topics: Adolescent; Adult; Animals; Humans; Male; Mice; Nutritional Status; Praziquantel; Pyridoxal Phosphate; Pyridoxine; Schistosomiasis mansoni; Tryptophan | 1992 |
New enzymatic method with tryptophanase for determining potassium in serum.
Topics: Ammonia; Escherichia coli; Glutamate Dehydrogenase; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ketoglutaric Acids; NADP; Potassium; Pyridoxal Phosphate; Tryptophan; Tryptophanase | 1992 |
On kynureninase activity.
Topics: Animals; Apoenzymes; Benzothiazoles; Cysteine; Dithionitrobenzoic Acid; Dithiothreitol; Enzyme Activation; Hydrolases; Kynurenine; Liver; Magnesium; Male; Phenylpyruvic Acids; Pyridoxal Phosphate; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Xanthurenates | 1991 |
The environments of Trp-248 and Trp-330 in tryptophan indole-lyase from Escherichia coli.
Topics: Binding Sites; Bromosuccinimide; Circular Dichroism; DNA Mutational Analysis; Escherichia coli; Lyases; Protein Conformation; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Tryptophanase | 1990 |
Role of tryptophan 248 in the active site of tryptophanase from Escherichia coli.
Topics: Animals; Binding Sites; Circular Dichroism; Escherichia coli; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Pyridoxal Phosphate; Spectrometry, Fluorescence; Substrate Specificity; Swine; Tryptophan; Tryptophanase | 1990 |
Mechanistic deductions from multiple kinetic and solvent deuterium isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Escherichia coli tryptophan indole-lyase.
Topics: Alanine; Binding, Competitive; Catalysis; Cysteine; Deuterium; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lyases; Oxindoles; Pyridoxal Phosphate; Solvents; Tryptophan; Tryptophanase | 1988 |
Purification and characterization of yeast L-kynurenine aminotransferase with broad substrate specificity.
Topics: Amino Acids; Borohydrides; Circular Dichroism; Coenzymes; Culture Media; Enzyme Inhibitors; Hydrogen-Ion Concentration; Immunodiffusion; Lyases; Molecular Weight; Pyridoxal Phosphate; Saccharomyces cerevisiae; Spectrophotometry; Substrate Specificity; Temperature; Transaminases; Tryptophan | 1986 |
Purification and active site modification studies on glyoxalase I from monkey intestinal mucosa.
Topics: Amino Acids, Dicarboxylic; Animals; Anions; Apoproteins; Binding Sites; Cations; Intestinal Mucosa; Lactoylglutathione Lyase; Lyases; Lysine; Macaca radiata; Molecular Weight; Pyridoxal Phosphate; Structure-Activity Relationship; Sulfhydryl Compounds; Tryptophan; Tyrosine | 1987 |
A common origin for enzymes involved in the terminal step of the threonine and tryptophan biosynthetic pathways.
Topics: Bacillus subtilis; Carbon-Oxygen Lyases; Escherichia coli; Information Systems; Lyases; Pyridoxal Phosphate; Saccharomyces cerevisiae; Salmonella typhimurium; Software; Threonine; Tryptophan; Tryptophan Synthase | 1987 |
Increased urinary excretion of tryptophan metabolites in rats exposed to nitrogen dioxide.
Topics: Animals; Body Weight; Kynurenic Acid; Liver; Male; NAD; NADP; Nitrogen Dioxide; Pyridoxal Phosphate; Rats; Rats, Inbred F344; Tryptophan; Xanthurenates | 1988 |
Dietary pyridoxine interaction with tryptophan or histidine on brain serotonin and histamine metabolism.
Topics: Animals; Brain; Diet; Drug Interactions; Histamine; Histidine; Hypothalamus; Male; Pyridoxal Phosphate; Pyridoxine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1988 |
[Peculiarities of nicotinic acid formation in coronary heart disease with special reference to heart arrhythmias].
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Coronary Disease; Female; Humans; Kynurenine; Lipid Metabolism; Male; Microscopy, Electron; Middle Aged; Myocardial Infarction; Myocardium; Niacin; Pyridoxal Phosphate; Ranidae; Rats; Rats, Inbred Strains; Tryptophan | 1988 |
Covalent structure of biodegradative threonine dehydratase of Escherichia coli: homology with other dehydratases.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Escherichia coli; Genes; Genes, Bacterial; Hydro-Lyases; L-Serine Dehydratase; Protein Binding; Pyridoxal Phosphate; Sequence Homology, Nucleic Acid; Tryptophan | 1987 |
[Stereochemical aspects of vitamin B6 enzyme reactions].
Topics: Chemical Phenomena; Chemistry; Decarboxylation; Diaminopimelic Acid; Molecular Conformation; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Tryptophanase | 1986 |
Vitamin B6 status of women suffering from premenstrual syndrome.
Topics: Adolescent; Adult; Aspartate Aminotransferases; Erythrocytes; Female; Humans; Menstrual Cycle; Middle Aged; Premenstrual Syndrome; Pyridoxal; Pyridoxal Kinase; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan; Xanthurenates | 1986 |
Effect of L-tryptophan excess and vitamin B6 deficiency on rat urinary bladder cancer promotion.
Topics: Alanine Transaminase; Animals; Cocarcinogenesis; FANFT; Male; Ornithine Decarboxylase; Pyridoxal Phosphate; Rats; Rats, Inbred F344; Serotonin; Tryptophan; Urinary Bladder Neoplasms; Vitamin B 6 Deficiency | 1987 |
Energy transfer from tryptophan residues to pyridoxal 5'-phosphate at the active site of ribulose-1,5-bisphosphate carboxylase/oxygenase.
Topics: Binding Sites; Mathematics; Plants; Pyridoxal Phosphate; Ribulose-Bisphosphate Carboxylase; Spectrometry, Fluorescence; Tryptophan | 1985 |
Differences in vitamin B6 status indicator responses between young and middle-aged women fed constant diets with two levels of vitamin B6.
Topics: Adult; Age Factors; Diet; Dietary Carbohydrates; Female; Humans; Kynurenic Acid; Middle Aged; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan; Xanthurenates | 1985 |
The effect of dietary protein on the metabolism of vitamin B-6 in humans.
Topics: Adult; Body Weight; Dietary Proteins; Energy Intake; Feces; Humans; Male; Nitrogen; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan | 1985 |
Effect of oral contraceptives on the plasma concentration of pyridoxal phosphate.
Topics: Adult; Age Factors; Apoproteins; Body Temperature; Contraceptives, Oral; Enterococcus faecalis; Estrogens; Female; Humans; Menstruation; Middle Aged; Nutritional Physiological Phenomena; Pyridoxal Phosphate; Time Factors; Tryptophan; Tyrosine Decarboxylase; Vitamin B 6 Deficiency; Xanthurenates | 1974 |
Purification and properties of 5-hydroxytryptophan decarboxylase from monkey small intestine.
Topics: 5-Hydroxytryptophan; Amines; Animals; Aspartic Acid; Benzoates; Carboxy-Lyases; Edetic Acid; Glutamates; Glutathione; Haplorhini; Histidine; Intestine, Small; Keto Acids; Kinetics; Male; Mercaptoethanol; Metals; Phenylalanine; Pyridoxal Phosphate; Tryptophan; Tyrosine | 1970 |
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1970 |
Indole channeling by tryptophan synthase of neurospora.
Topics: Binding Sites; Biological Evolution; Carbon Radioisotopes; Glycerophosphates; Indoles; Kinetics; Mathematics; Neurospora; Neurospora crassa; Pyridoxal Phosphate; Serine; Time Factors; Tryptophan; Tryptophan Synthase | 1974 |
Synthesis of indoleacetic acid from tryptophan via indolepyruvic acid in cell-free extracts of pea seedlings.
Topics: Aldehydes; Carbon Isotopes; Cell-Free System; Chromatography, Ion Exchange; Chromatography, Thin Layer; Indoleacetic Acids; Indoles; Ketoglutaric Acids; NAD; Plants; Pyridoxal Phosphate; Pyruvates; Thiamine Pyrophosphate; Tryptophan | 1968 |
Studies with tryptophan metabolites in vitro. 3. The effect of schistosomicidal drugs on kynureninase and kynurenine transaminase of normal mouse liver.
Topics: Animals; Anti-Infective Agents; Antimony; Benzenesulfonates; Calcium; Imidazoles; In Vitro Techniques; Kynurenic Acid; Kynurenine; Liver; Magnesium; Mice; ortho-Aminobenzoates; Pyridoxal Phosphate; Tartrates; Transaminases; Tryptophan | 1969 |
Effects of steroid conjugates on availability of pyridoxal phosphate for kynureninase and kynurenine aminotransferase activity.
Topics: Animals; Binding Sites; Body Weight; Castration; Depression, Chemical; Diet; Diethylstilbestrol; Estrogens, Conjugated (USP); Female; Hydrolases; Kidney; Kynurenine; Liver; Male; Mitochondria; Mitochondria, Liver; Organ Size; Ovary; Protein Binding; Pyridoxal Phosphate; Rats; Sex Factors; Transaminases; Tryptophan | 1971 |
Evidence for distinct kynureninase and hydroxykynureninase activities in Neurospora crassa.
Topics: Cell-Free System; Chromatography, DEAE-Cellulose; Culture Media; Enzyme Induction; Fluorometry; Hydrolases; Kynurenine; Magnesium Sulfate; Models, Chemical; NAD; Neurospora; ortho-Aminobenzoates; Pyridoxal Phosphate; Tryptophan | 1971 |
Adaptive response of tryptophan pyrrolase and tyrosine transaminase in rat liver after partial hepatectomy and laparotomy.
Topics: Adrenalectomy; Animals; Cortisone; Dactinomycin; Enzyme Induction; Hepatectomy; Laparotomy; Liver; Male; Peroxidases; Pyridoxal Phosphate; Rats; Time Factors; Tryptophan; Tryptophan Oxygenase; Tyrosine Transaminase | 1968 |
Effects of steroid and nonsteroid metabolites on enzyme conformation and pyridoxal phosphate binding.
Topics: Animals; Buffers; Castration; Diethylstilbestrol; Estrogens; Female; In Vitro Techniques; Kidney; Kynurenine; Liver; Male; Mitochondria, Liver; Ovary; Protein Binding; Pyridoxal Phosphate; Rats; Steroids; Transaminases; Transferases; Tryptophan; Tyrosine Transaminase; Vitamin B 6 Deficiency | 1969 |
Tryptophan pyrrolase, tryptophan and tyrosine transaminase changes during allylisopropylacetamide-induced porphyria in the rat.
Topics: Adrenal Glands; Adrenalectomy; Amides; Animals; Behavior, Animal; Enzyme Induction; Fasting; Female; Hypophysectomy; Liver; Peroxidases; Pituitary Gland; Porphyrias; Porphyrins; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine Transaminase | 1970 |
Inversion in the metabolism of D-tryptophan in the rabbit and the rat.
Topics: Aerobiosis; Amination; Anaerobiosis; Animals; Chromatography, Paper; D-Amino-Acid Oxidase; Deamination; Diet; Indoles; Kidney; Kynurenic Acid; Kynurenine; Liver; Male; Organ Specificity; ortho-Aminobenzoates; Oryza; Oxidation-Reduction; Oxygen Consumption; Pyridoxal Phosphate; Pyruvates; Rabbits; Rats; Species Specificity; Stereoisomerism; Tryptophan | 1971 |
Effect of pyridoxine defienciency on inducibility and circadian rhythms of some pyridoxine-dependent enzymes.
Topics: Acetamides; Allyl Compounds; Animals; Body Weight; Carbon Isotopes; Carboxy-Lyases; Circadian Rhythm; Diet; Enzyme Activation; Enzyme Induction; Hydrocortisone; Liver; Male; Norepinephrine; Peroxidases; Pyridoxal Phosphate; Pyridoxine; Rats; Transaminases; Tryptophan; Tyrosine Transaminase; Vitamin B 6 Deficiency | 1971 |
Transamination of aromatic amino acids in rat liver and brain.
Topics: Amino Acids; Animals; Brain; Chromatography, Gel; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Enzyme Activation; Hydrazines; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Mitochondria, Liver; Phenylalanine; Protein Binding; Pyridoxal Phosphate; Pyridoxine; Rats; Spectrophotometry; Subcellular Fractions; Transaminases; Tryptophan; Tyrosine Transaminase; Ultraviolet Rays | 1972 |
The effects of salicylate on the activity of rat liver tyrosine-2-oxoglutarate aminotransferase in vitro and in vivo.
Topics: Adrenalectomy; Animals; Dactinomycin; Drug Antagonism; Enzyme Activation; Enzyme Induction; Hydrocortisone; In Vitro Techniques; Injections, Intraperitoneal; Liver; Male; Protein Binding; Pyridoxal Phosphate; Pyridoxine; Rats; Salicylates; Spectrophotometry; Tryptophan; Tyrosine Transaminase; Ultraviolet Rays | 1972 |
Constitutive aromatic L-amino acid decarboxylase from Micrococcus percitreus.
Topics: Carboxy-Lyases; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Drug Stability; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Micrococcus; Molecular Weight; Phenylalanine; Protamines; Protein Binding; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Tyrosine; Ultracentrifugation | 1974 |
The interactions between biogenic amines and pyridoxal, pyridoxal phosphate, and pyridoxal kinase.
Topics: 5-Hydroxytryptophan; Adenosine Triphosphate; Amines; Animals; Biogenic Amines; Brain; Cattle; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Dopamine; Norepinephrine; Phosphotransferases; Picolines; Pyridoxal Phosphate; Pyridoxine; Serotonin; Spectrophotometry; Tryptophan; Tyrosine; Zinc | 1972 |
An improved apotryptophanase assay for pyridoxal phosphate.
Topics: Aldehydes; Ammonium Sulfate; Aniline Compounds; Chemical Precipitation; Colorimetry; Escherichia coli; Hydro-Lyases; Methods; Methylamines; Microchemistry; Pyridoxal Phosphate; Time Factors; Tryptophan | 1972 |
The tryptophanase from Escherichia coli K-12. I. Purification, physical properties, and quaternary structure.
Topics: Ammonium Sulfate; Borohydrides; Centrifugation, Zonal; Chemical Precipitation; Detergents; Electrophoresis, Disc; Escherichia coli; Freeze Drying; Hydro-Lyases; Macromolecular Substances; Molecular Weight; Penicillamine; Protein Binding; Pyridoxal Phosphate; Sulfuric Acids; Tryptophan; Ultracentrifugation | 1972 |
The chemical structure of tryptophanase from Escherichia coli. II. The structure of tryptophanase monomer.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Ammonium Sulfate; Binding Sites; Borohydrides; Carbon Isotopes; Carboxypeptidases; Chemical Precipitation; Crystallization; Culture Media; Cyanogen Bromide; Escherichia coli; Hydro-Lyases; Indoles; Iodoacetates; Macromolecular Substances; Methionine; Molecular Weight; Peptides; Pyridoxal Phosphate; Pyruvates; Tryptophan | 1972 |
The chemical structure of tryptophanase from Escherichia coli. 3. Isolation and amino acid sequence of the tryptic peptides.
Topics: Alkylation; Amino Acid Sequence; Amino Acids; Binding Sites; Borohydrides; Carboxypeptidases; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Cyanogen Bromide; Electrophoresis, Paper; Escherichia coli; Hydro-Lyases; Iodoacetates; Leucyl Aminopeptidase; Macromolecular Substances; Oxidation-Reduction; Peptides; Pyridoxal Phosphate; Thiocyanates; Trypsin; Tryptophan | 1972 |
Reversibility of the tryptophanase reaction: synthesis of tryptophan from indole, pyruvate, and ammonia.
Topics: Acrylates; Ammonia; Ammonium Chloride; Biodegradation, Environmental; Catalysis; Escherichia coli; Hydro-Lyases; Hydrogen-Ion Concentration; Indoles; Kinetics; Osmolar Concentration; Potassium Chloride; Pyridoxal Phosphate; Pyruvates; Time Factors; Tryptophan | 1972 |
Physical studies comparing a genetically fused enzyme of the histidine operon with its component enzymes.
Topics: Alcohol Oxidoreductases; Amino Alcohols; Chemical Phenomena; Chemistry; Circular Dichroism; Genetics, Microbial; Histidine; Hydrogen-Ion Concentration; Imidazoles; Macromolecular Substances; Multienzyme Complexes; Operon; Peptides; Protein Conformation; Pyridoxal Phosphate; Salmonella typhimurium; Schiff Bases; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Transaminases; Tryptophan; Tyrosine | 1973 |
Location of the indole binding site in human serum albumin. Characterization of major cyanogen bromide fragments with respect to affinity labeling positions.
Topics: Acetates; Binding Sites; Bromine; Chemical Phenomena; Chemistry; Chlorine; Cyanogen Bromide; Dansyl Compounds; Humans; Indoles; Peptides; Propionates; Pyridoxal Phosphate; Serum Albumin; Spectrophotometry, Ultraviolet; Tritium; Tryptophan | 1973 |
Primary acquired sideroblastic anaemia: response to treatment with pyridoxal-5-phosphate.
Topics: Aged; Anemia, Sideroblastic; Ascorbic Acid; Female; Folic Acid; Hemoglobinometry; Humans; Pyridoxal Phosphate; Pyridoxine; Reticulocytes; Tryptophan | 1973 |
Fluorescence quenching, a tool for probing conformational changes in glycogen phosphorylase.
Topics: Animals; Apoproteins; Fluorescence; Iodides; Kinetics; Methods; Muscles; Myocardium; Phosphorylases; Protein Conformation; Pyridoxal Phosphate; Rabbits; Spectrometry, Fluorescence; Spectrum Analysis; Swine; Tryptophan; Urea | 1973 |
Effect of copper status on the urinary excretion of tryptophan metabolites and amino acids by the rat.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Copper; Deficiency Diseases; Heart; Hemoglobins; Kidney; Kynurenic Acid; Liver; Male; Organ Size; Pyridoxal Phosphate; Rats; Spleen; Taurine; Tryptophan; Urea; Xanthurenates | 1973 |
A new thiol-dependent transamination reaction catalyzed by the B protein of Escherichia coli tryptophan synthetase.
Topics: Amino Acids; Aspartate Aminotransferases; Bacterial Proteins; Carbon Isotopes; Chromatography, Paper; Dialysis; Electrophoresis; Escherichia coli; Hydro-Lyases; Keto Acids; Kinetics; Mercaptoethanol; Pyridoxal Phosphate; Pyruvates; Serine; Spectrophotometry; Sulfhydryl Compounds; Time Factors; Tryptophan | 1968 |
Fluorescence studies of substrate and subunit interactions of the beta-2 protein of Escherichia coli tryptophan synthetase.
Topics: Bacterial Proteins; Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Fluorescence; Fluorometry; Hydrogen-Ion Concentration; Indoles; Ligases; Pyridoxal Phosphate; Serine; Spectrophotometry; Threonine; Tryptophan | 1968 |
Properties and catalytic activities of vitamin B6 N-oxide.
Topics: Amines; Aspartate Aminotransferases; Catalysis; Chelating Agents; Coenzymes; Escherichia coli; Hot Temperature; Hydro-Lyases; Ketoglutaric Acids; Kinetics; Magnetic Resonance Spectroscopy; Optical Rotatory Dispersion; Oxides; Phosphates; Pyridines; Pyridoxal Phosphate; Pyridoxine; Serine; Spectrum Analysis; Tryptophan | 1969 |
Subunit structure of the B component of Escherichia coli tryptophan synthetase.
Topics: Amino Acids; Bacterial Proteins; Boron Compounds; Chemical Phenomena; Chemistry; Electrophoresis; Escherichia coli; Formates; Hydro-Lyases; Hydrogen Peroxide; Molecular Weight; Oxidation-Reduction; Peptides; Pyridoxal Phosphate; Sulfhydryl Compounds; Tryptophan; Ultracentrifugation; Urea | 1969 |
Tryptophan synthase from Nicotiana tabacum.
Topics: Animals; Antigen-Antibody Reactions; Biological Evolution; Centrifugation, Density Gradient; Chemical Precipitation; Culture Techniques; Escherichia coli; Glycerophosphates; Hot Temperature; Hydro-Lyases; Hydrogen-Ion Concentration; Indoles; Kinetics; Nicotiana; Plants; Plants, Toxic; Pyridoxal Phosphate; Rabbits; Serine; Tritium; Tryptophan | 1968 |
Properties and catalytic activities of omega-hydroxy derivatives of vitamin B6.
Topics: Aspartate Aminotransferases; Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Hydro-Lyases; Ketoglutaric Acids; Kinetics; Magnetic Resonance Spectroscopy; Phosphates; Pyridines; Pyridoxal Phosphate; Pyridoxine; Spectrum Analysis; Tryptophan | 1969 |
A steady-state kinetic investigation of the reaction mechanism of the tryptophan synthetase of Escherichia coli.
Topics: Binding Sites; Chromatography, Gel; Escherichia coli; Feedback; Fluorescence; Glyceraldehyde; Glycerides; Hydro-Lyases; Indoles; Kinetics; Models, Biological; Models, Chemical; Models, Structural; Phosphoric Acids; Pyridoxal Phosphate; Serine; Tryptophan | 1970 |
[Differential action of 2,3,4-trihydroxybenzylhydrazine on amino acid decarboxylases].
Topics: 5-Hydroxytryptophan; Animals; Aspartate Aminotransferases; Brain; Carboxy-Lyases; Dopa Decarboxylase; Escherichia coli; Glutamates; Hydrazines; Kidney; Pyridoxal Phosphate; Rabbits; Tryptophan; Tyrosine | 1967 |
Properties and subunit structure of the B component of Pseudomonas putida tryptophan synthetase.
Topics: Alanine; Amino Acids; Borohydrides; Carboxypeptidases; Catalysis; Chemical Precipitation; Chromatography, Gel; Cross Reactions; Detergents; Drug Stability; Electrophoresis, Disc; Escherichia coli; Formates; Glycerophosphates; Hot Temperature; Hydro-Lyases; Immune Sera; Immunodiffusion; Indoles; Kinetics; Macromolecular Substances; Mercaptoethanol; Molecular Weight; Oxidation-Reduction; Pseudomonas; Pyridoxal Phosphate; Serine; Spectrophotometry; Sulfuric Acids; Tryptophan; Ultracentrifugation; Urea | 1971 |
Tryptophanase from Bacillus alvei. I. Subunit structure.
Topics: Amino Acid Sequence; Amino Acids; Apoproteins; Bacillus; Borohydrides; Chromatography, Paper; Electrophoresis; Electrophoresis, Paper; Formates; Guanidines; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxylamines; Macromolecular Substances; Molecular Weight; Oxidation-Reduction; Peptides; Pyridoxal Phosphate; Sodium Dodecyl Sulfate; Trypsin; Tryptophan; Ultracentrifugation; Urea | 1972 |
Studies with tryptophan metabolites in vitro. V. Effect of the methanesulphonate derivative of hycanthone (etrenol) and lead acetate on kynureninase and kynurenine transaminase of normal mouse liver.
Topics: Acetates; Anthelmintics; Ethylamines; Hydrolases; Ketones; Kynurenic Acid; Kynurenine; Lead; Liver; ortho-Aminobenzoates; Osmolar Concentration; Pyridoxal Phosphate; Spectrum Analysis; Sulfonic Acids; Sulfur; Transaminases; Tryptophan; Ultraviolet Rays; Xanthenes | 1972 |
Tryptophan metabolism in rheumatoid neuropathies.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Child; Child, Preschool; Electrophysiology; Female; Humans; Kynurenine; Male; Middle Aged; Neurologic Manifestations; Nicotinic Acids; ortho-Aminobenzoates; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Xanthurenates | 1972 |
Phosphorylated analogs of vitamin B 6 modified in the 5' position and on the phosphate group: synthesis and interaction with pyridoxine phosphate oxidase and certain apoenzymes.
Topics: Alcohol Oxidoreductases; Animals; Arginine; Aspartate Aminotransferases; Binding Sites; Carboxy-Lyases; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Glutamates; Hydro-Lyases; L-Serine Dehydratase; Liver; Magnetic Resonance Spectroscopy; Phosphoric Acids; Phosphorylases; Pyridoxal Phosphate; Pyridoxine; Rabbits; Spectrophotometry; Structure-Activity Relationship; Tryptophan; Ultraviolet Rays | 1972 |
[Metabolic and catalytic functions of vitamin B6].
Topics: Alanine; Apoproteins; Catalysis; Chemical Phenomena; Chemistry; Enzyme Activation; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1972 |
Anergy and tryptophan metabolism in Hodgkin's disease.
Topics: Adolescent; Adult; Age Factors; Amino Acids; Anemia; Antigens; Candida; Coccidioides; Deficiency Diseases; Female; Histoplasmin; Hodgkin Disease; Humans; Kynurenine; Lymphopenia; Male; Middle Aged; Phenylbutyrates; Pyridoxal Phosphate; Sex Factors; Skin Tests; Tryptophan; Tuberculin; Xanthurenates | 1971 |
Evidence for the binding of pyridoxal 5'-phosphate in a hydrophobic region of glycogen phosphorylase b dimer.
Topics: Animals; Binding Sites; Electrochemistry; Electrophoresis, Disc; Electrophoresis, Paper; Energy Transfer; Fluorescence; Glucosyltransferases; Hydrogen-Ion Concentration; Hydroxylamines; Imidazoles; Muscles; Oxidation-Reduction; Phosphorylases; Polymers; Protein Binding; Pyridoxal Phosphate; Rabbits; Time Factors; Tryptophan; Urea | 1971 |
The role of vitamin B6 in the toxicity of hydrazines.
Topics: Amino Acids; Animals; Brain Chemistry; Calcium; Hydrazines; Injections; Injections, Intraperitoneal; Potassium; Pyridoxal Phosphate; Pyridoxine; Rats; Seizures; Sodium; Tryptophan; Tyrosine | 1969 |
Abnormal pyridoxine metabolism in toxemia of pregnancy.
Topics: Brain; Brain Chemistry; Female; Humans; Kidney; Liver; Phosphotransferases; Placenta; Pre-Eclampsia; Pregnancy; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1969 |
Pyridoxal phosphate in acute intermittent porphyria.
Topics: Adult; Female; Humans; Levulinic Acids; Male; Middle Aged; Porphyrias; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Xanthurenates | 1969 |
Effect of analogs of phenylalanine and tryptophan on kinetics of DOPA decarboxylase in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Male; Methyldopa; Phenylalanine; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine | 1966 |
Formiminotransferase deficiency syndrome associated with megaloblastic anemia responsive to pyridoxine or folic acid.
Topics: Anemia, Macrocytic; Blood Cell Count; Bone Marrow Examination; Cerebral Ventriculography; Erythrocytes; FIGLU Test; Folic Acid; Humans; Infant; Infusions, Parenteral; Injections, Intramuscular; Liver; Male; Metabolism, Inborn Errors; Pyridoxal Phosphate; Tetrahydrofolate Dehydrogenase; Transferases; Tryptophan | 1968 |
Association of the alpha and beta-2 subunits of the tryptophan synthetase of Escherichia coli.
Topics: Bacterial Proteins; Chromatography, Gel; Escherichia coli; Hydro-Lyases; In Vitro Techniques; Indoles; Molecular Biology; Mutation; Pyridoxal Phosphate; Serine; Sodium Chloride; Tryptophan; Ultracentrifugation | 1966 |
Abnormalities of tryptophan metabolism and plasma pyridoxal phosphate in Hodgkin's disease.
Topics: Adolescent; Adult; Anemia; Carbon Isotopes; Female; Hodgkin Disease; Humans; Kynurenine; Male; Middle Aged; Pyridoxal Phosphate; Pyridoxine; Skin Tests; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1970 |
Tryptophan metabolism in the magnesium deficient rat.
Topics: Animals; Diet; Female; Indoles; Kynurenic Acid; Magnesium Deficiency; ortho-Aminobenzoates; Pyridoxal Phosphate; Pyridoxine; Rats; Tryptophan; Xanthurenates | 1970 |
Studies on the effect of reserpine therapy on the functional capacity of the tryptophan-niacin pathway in smoker and non-smoker males.
Topics: Adult; Aminohippuric Acids; Carboxy-Lyases; Catecholamines; Glucuronates; Humans; Isonicotinic Acids; Kynurenic Acid; Kynurenine; Male; Nicotine; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Pyridoxal Phosphate; Pyridoxine; Reserpine; Smoking; Tryptophan; Xanthurenates | 1970 |
[Vitamin B6 deficiency in patients with leg ulcers and in their family members].
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Paper; Female; Humans; Kynurenine; Leg Ulcer; Male; Middle Aged; Pedigree; Pyridoxal Phosphate; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1970 |
The effect of estrogens on pyridoxal phosphate dependent enzymes in patients with cancer of the prostate.
Topics: Alanine Transaminase; Aminohippuric Acids; Aspartate Aminotransferases; Carboxy-Lyases; Chlorotrianisene; Coenzymes; Diethylstilbestrol; Erythrocytes; Glucuronates; Humans; Kynurenine; Male; ortho-Aminobenzoates; Prostatic Neoplasms; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1971 |
Vitamin B6 dependent xanthurenic aciduria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aspartate Aminotransferases; Autoanalysis; Child; Child, Preschool; Chromatography, Thin Layer; Electroencephalography; Female; Humans; Hydrolases; Intellectual Disability; Kynurenic Acid; Liver; Male; Pedigree; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Xanthurenates | 1967 |
[Quantitative determination of the biologic antivitamin B6 effect of pyridoxal antagonists].
Topics: Animals; Injections, Intraperitoneal; Male; Pyridoxal Phosphate; Pyridoxine; Rats; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1967 |
Pyridoxine and riboflavin status in the Paterson-Kelly syndrome.
Topics: Adult; Aged; Anemia, Hypochromic; Deglutition Disorders; Erythrocytes; Female; Humans; Male; Middle Aged; Pyridoxal Phosphate; Pyridoxine; Riboflavin; Riboflavin Deficiency; Transaminases; Tryptophan | 1968 |
The role of tris(hydroxymethyl)aminomethane and cysteine in the dissociation of tryptophanase.
Topics: Acrylic Resins; Bacillus; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Cysteine; Hydrogen-Ion Concentration; Lyases; Penicillamine; Pyridoxal Phosphate; Tromethamine; Tryptophan | 1968 |
Studies with tryptophan metabolites in vitro. Kynurenine metabolism in kidneys of mice infested with Schistosoma mansoni.
Topics: Animals; Hydrolases; In Vitro Techniques; Kidney; Kynurenic Acid; Kynurenine; Mice; ortho-Aminobenzoates; Pyridoxal Phosphate; Schistosomiasis; Tryptophan; Urinary Bladder Neoplasms | 1968 |
Tryptophan transaminase from Clostridium sporogenes.
Topics: Buffers; Cell-Free System; Centrifugation, Density Gradient; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Ion Exchange; Clostridium; Electrophoresis; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Models, Biological; Molecular Weight; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry; Transaminases; Tryptophan; Tyrosine | 1968 |
Pyridoxal phosphate concentration in plasma and tryptophan load test during pregnancy.
Topics: Adult; Chromatography, Thin Layer; Estrogens; Female; Humans; Pregnancy; Pyridoxal Phosphate; Time Factors; Tryptophan; Xanthurenates | 1969 |
Aminotransferases of Agrobacterium tumefaciens. Transamination between tryptophan and phenylpyruvate.
Topics: Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Phenylalanine; Phenylpyruvic Acids; Protein Denaturation; Pyridoxal Phosphate; Rhizobium; Transaminases; Tryptophan | 1964 |
The utilization of tryptophan by neurospora.
Topics: Alanine; In Vitro Techniques; Indoles; Mutation; Neurospora; ortho-Aminobenzoates; Pyridoxal Phosphate; Pyruvates; Temperature; Tryptophan | 1965 |
Is the tryptophan load test a valid index for a chemically-induced vitamin B6 deficiency?
Topics: Acetates; Animals; Brain Chemistry; Liver; Oxalates; Phosphates; Pyridoxal Phosphate; Rats; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1966 |
Tryptophan load tests and pyridoxal-5-phosphate levels in epileptic children. I. Non-progressive brain damage and degenerative brain disorders.
Topics: Adolescent; Brain Diseases; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Xanthurenates | 1966 |
Tryptophan load tests and pyridoxal-5-phosphate levels in epileptic children. II. Cryptogenic epilepsy.
Topics: Child; Child, Preschool; Epilepsy; Humans; Infant; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1966 |
Physical and catalytic properties of tryptophanase from Bacillus alvei.
Topics: Bacillus; Catalysis; Dialysis; Kinetics; Lyases; Molecular Weight; Pyridoxal Phosphate; Tryptophan; Ultracentrifugation | 1966 |
A study of tryptophan metabolism in psychotic children.
Topics: Autoradiography; Carbon Isotopes; Child; Child, Preschool; Female; Humans; Kynurenine; Male; Metabolic Diseases; ortho-Aminobenzoates; Pyridoxal Phosphate; Pyridoxine; Schizophrenia, Childhood; Tryptophan; Xanthurenates | 1966 |
Amino acid composition and terminal residues of aspartate aminotransferase from ox heart.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Autoanalysis; Cattle; Cysteine; Myocardium; Nitrogen; Phosphorus; Pyridoxal Phosphate; Tryptophan | 1966 |
Biochemical and physiological changes in vitamin B6 deficiency.
Topics: Alanine Transaminase; Anemia, Hypochromic; Central Nervous System Diseases; Cysteine; Erythrocytes; Humans; Kynurenic Acid; Kynurenine; Male; Nicotinic Acids; Pyridoxal Phosphate; Pyridoxine; Serotonin; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1967 |
The activation of chick liver tyrosine transaminase in vitro.
Topics: Animals; Glutamates; Hydrocortisone; In Vitro Techniques; Injections, Intraperitoneal; Ketoglutaric Acids; Liver; Poultry; Pyridoxal Phosphate; Transaminases; Tryptophan; Tyrosine | 1967 |
Synthesis and properties of some N-pyridoxyl-L-amino acids and N-(5-phosphopyridoxyl)-L-amino acids.
Topics: Alanine; Aldehydes; Arginine; Aspartic Acid; Chemistry, Organic; Chromatography, Paper; Glutamates; Organic Chemistry Phenomena; Pyridines; Pyridoxal Phosphate; Pyrrolidinones; Serine; Tryptophan; Tyrosine | 1967 |
The possible role of thyroid aromatic amino acid decarboxylase in thyroxine biosynthesis.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cattle; Diiodotyrosine; Histidine; In Vitro Techniques; Phenylalanine; Pyridoxal Phosphate; Thyroid Gland; Thyroxine; Tryptophan; Tyrosine | 1967 |
Mitochondrial glutamate-aspartate transaminase. I. Structural comparison with the supernatant isozyme.
Topics: Amino Acids; Aspartate Aminotransferases; Azo Compounds; Boron; Electrophoresis; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoenzymes; Ketoglutaric Acids; Mitochondria; Myocardium; Oxidation-Reduction; Peptides; Protein Binding; Pyridoxal Phosphate; Spectrophotometry; Trypsin; Tryptophan | 1967 |
Studies with tryptophan metabolites in vitro. Kynurenine metabolism in liver homogenates of normal and Schistosoma mansoni-infested mice.
Topics: Animals; Kinetics; Kynurenine; Liver; Mice; ortho-Aminobenzoates; Perfusion; Pyridoxal Phosphate; Pyridoxine; Schistosomiasis; Tryptophan | 1967 |
Enzymatic determination of pyridoxal phosphate in plasma by decarboxylation of L-tyrosine-14 C (U) and a comparison with the tryptophan load test.
Topics: Adult; Aged; Carbon Isotopes; Child; Chromatography, Paper; Clinical Enzyme Tests; Heparin; Humans; Methods; Pyridoxal Phosphate; Pyridoxine; Tryptophan; Tyramine; Tyrosine; Tyrosine Decarboxylase; Vitamin B Complex; Xanthurenates | 1967 |
High level of pyridoxal 5'-phosphate in the cerebrospinal fluid of adult celiac patients.
Topics: Adult; Celiac Disease; Humans; Hydroxyindoleacetic Acid; Middle Aged; Pyridoxal Phosphate; Serotonin; Tryptophan | 1982 |
Effects of oestrogen administration on vitamin B6 and tryptophan metabolism in the rat.
Topics: Animals; Estrogens, Conjugated (USP); Estrone; Female; Hydrolases; Pyridoxal Phosphate; Pyridoxine; Rats; Rats, Inbred Strains; Tissue Distribution; Tryptophan | 1982 |
Interactions of tryptophan synthase, tryptophanase, and pyridoxal phosphate with oxindolyl-L-alanine and 2,3-dihydro-L-tryptophan: support for an indolenine intermediate in tryptophan metabolism.
Topics: Alanine; Binding, Competitive; Chemical Phenomena; Chemistry; Escherichia coli; Kinetics; Lyases; Mass Spectrometry; Oxindoles; Pyridoxal Phosphate; Spectrophotometry; Tryptophan; Tryptophan Synthase; Tryptophanase | 1984 |
Structural and functional alterations of E. coli tryptophan synthase upon binding of pyridoxal 5'-phosphate.
Topics: Binding Sites; Escherichia coli; Indoles; Kinetics; Pyridoxal Phosphate; Serine; Tryptophan; Tryptophan Synthase | 1984 |
Pyridoxal phosphate, tryptophan, and tyrosine in blood and cerebrospinal fluid in elderly patients.
Topics: Adult; Age Factors; Aged; Humans; Hydrocephalus; Middle Aged; Parkinson Disease; Pyridoxal Phosphate; Tryptophan; Tyrosine | 1984 |
Dye-sensitized photo-oxidation of pig kidney Dopa decarboxylase.
Topics: Amino Acids; Animals; Aromatic-L-Amino-Acid Decarboxylases; Coloring Agents; Dopa Decarboxylase; Kidney; Light; Oxidation-Reduction; Photochemistry; Proflavine; Pyridoxal Phosphate; Swine; Tryptophan | 1984 |
The synthesis of 5-hydroxytryptamine from tryptophan and 5-hydroxytryptophan in the cestode Hymenolepis diminuta.
Topics: 5-Hydroxytryptophan; Animals; Hymenolepis; Iproniazid; Pyridoxal Phosphate; Serotonin; Tryptophan | 1983 |
High doses of vitamin B6 in the rat are associated with inhibition of hepatic tryptophan metabolism and increased uptake of tryptophan into the brain.
Topics: Animals; Biological Transport; Brain; Carbon Radioisotopes; Female; Liver; Pyridoxal Phosphate; Pyridoxine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tryptophan Oxygenase | 1984 |
Chemical modification of critical catalytic residues of lysine, arginine, and tryptophan in human glucose phosphate isomerase.
Topics: Affinity Labels; Arginine; Bromosuccinimide; Circular Dichroism; Cyclohexanones; Diacetyl; Female; Glucose-6-Phosphate Isomerase; Humans; Kinetics; Lysine; Molecular Weight; Placenta; Pregnancy; Protein Binding; Protein Conformation; Pyridoxal Phosphate; Tryptophan | 1981 |
Fluorescence energy transfer in tryptophanase.
Topics: Chemical Phenomena; Chemistry; Energy Transfer; Escherichia coli; Lyases; Protein Binding; Pyridoxal Phosphate; Spectrometry, Fluorescence; Tryptophan; Tryptophanase | 1980 |
Inhibition of kynureninase (L-kynurenine hydrolase, EC 3 . 7. 1 . 3) by oestrone sulphate: an alternative explanation for abnormal results of tryptophan load tests in women receiving oestrogenic steroids.
Topics: Animals; Apoenzymes; Binding, Competitive; Estrone; Female; Hydrolases; Kinetics; Liver; Pyridoxal Phosphate; Rats; Tryptophan | 1981 |
Effect of natural oestrogens on tryptophan metabolism: evidence for interference of oestrogens with kynureninase.
Topics: Aged; Estradiol; Estriol; Estrogens; Female; Humans; Hydrolases; Kynurenine; Menopause; Middle Aged; NAD; Pyridoxal Phosphate; Pyridoxic Acid; Pyridoxine; Tryptophan | 1980 |
The effect of drugs on vitamin B6 function in the rat.
Topics: Animals; In Vitro Techniques; Isoniazid; Kynurenine; Lyases; Male; Pyridoxal Phosphate; Pyridoxine; Rats; Transaminases; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 1980 |
Role of leucine 201 of thermostable D-amino acid aminotransferase from a thermophile, Bacillus sp. YM-1.
Topics: Alanine; Alanine Transaminase; Bacillus; Bacterial Proteins; Base Sequence; Binding Sites; Catalysis; Circular Dichroism; D-Alanine Transaminase; Enzyme Activation; Enzyme Stability; Hot Temperature; Kinetics; Leucine; Molecular Sequence Data; Mutation; Pyridoxal Phosphate; Pyridoxamine; Spectrometry, Fluorescence; Tryptophan | 1995 |
Tryptophanase from Escherichia coli: catalytic and spectral properties in water-organic solvents.
Topics: Alanine; Catalysis; Cysteine; Dimethylformamide; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Methanol; Pyridoxal Phosphate; Solutions; Spectrophotometry, Ultraviolet; Stereoisomerism; Substrate Specificity; Tryptophan; Tryptophanase; Water | 1994 |
Imidazole acetol phosphate aminotransferase in Zymomonas mobilis: molecular genetic, biochemical, and evolutionary analyses.
Topics: Amino Acid Sequence; Amino Acids; Base Sequence; Biological Evolution; Cloning, Molecular; Escherichia coli; Genes, Bacterial; Genetic Linkage; Molecular Sequence Data; Multigene Family; Pyridoxal Phosphate; Restriction Mapping; RNA, Messenger; Sequence Analysis; Sequence Homology, Amino Acid; Substrate Specificity; Transaminases; Tryptophan; Zymomonas | 1995 |
Ligand-mediated changes in the tryptophan synthase indole tunnel probed by nile red fluorescence with wild type, mutant, and chemically modified enzymes.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Codon; Computer Graphics; Computer Simulation; Cysteine; Escherichia coli; Fluorescent Dyes; Indoles; Iodides; Kinetics; Ligands; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oxazines; Phenylalanine; Point Mutation; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Tryptophan; Tryptophan Synthase | 1995 |
NMR studies of 1H resonances in the 10-18-ppm range for aspartate aminotransferase from Escherichia coli.
Topics: Alanine; Amino Acid Sequence; Asparagine; Aspartate Aminotransferases; Escherichia coli; Histidine; Hydrogen; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Sensitivity and Specificity; Tryptophan | 1994 |
Product binding to the alpha-carboxyl subsite results in a conformational change at the active site of O-acetylserine sulfhydrylase-A: evidence from fluorescence spectroscopy.
Topics: Acetates; Binding Sites; Circular Dichroism; Cysteine; Cysteine Synthase; Hydrogen-Ion Concentration; Protein Conformation; Pyridoxal Phosphate; Regression Analysis; Salmonella typhimurium; Schiff Bases; Serine; Spectrometry, Fluorescence; Tryptophan | 1994 |
Synthesis and spectral characterization of 5'-phosphopyridoxyl-D,L-7-azatryptophan, a photophysical probe of protein structure and dynamics.
Topics: Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; Proteins; Pyridoxal Phosphate; Spectrophotometry; Tryptophan | 1994 |
Spinach chloroplast 0-acetylserine (thiol)-lyase exhibits two catalytically non-equivalent pyridoxal-5'-phosphate-containing active sites.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carbon-Oxygen Lyases; Catalysis; Chloroplasts; Cysteine Synthase; Escherichia coli; Fluorescent Dyes; Fluorometry; Genes, Plant; Genes, Synthetic; Kinetics; Lyases; Models, Chemical; Molecular Sequence Data; Multienzyme Complexes; Protein Conformation; Pyridoxal Phosphate; Recombinant Proteins; Saccharomyces cerevisiae Proteins; Spinacia oleracea; Titrimetry; Tryptophan | 1996 |
Interaction of pyridoxal 5'-phosphate with tryptophan-139 at the subunit interface of dimeric D-amino acid transaminase.
Topics: Catalysis; Circular Dichroism; D-Alanine Transaminase; Enzyme Stability; Hot Temperature; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Transaminases; Tryptophan | 1996 |
Mutation of an active site residue of tryptophan synthase (beta-serine 377) alters cofactor chemistry.
Topics: Aspartic Acid; Bacterial Proteins; Binding Sites; Glutamates; Hydrogen-Ion Concentration; Macromolecular Substances; Mutagenesis, Site-Directed; Pyridoxal Phosphate; Schiff Bases; Serine; Spectrum Analysis; Structure-Activity Relationship; Tryptophan; Tryptophan Synthase | 1998 |
Trypsin cleavage of human cystathionine beta-synthase into an evolutionarily conserved active core: structural and functional consequences.
Topics: Amino Acid Sequence; Binding Sites; Conserved Sequence; Cystathionine beta-Synthase; Enzyme Activation; Heme; Hot Temperature; Humans; Hydrolysis; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Protein Denaturation; Pyridoxal Phosphate; Recombinant Proteins; S-Adenosylmethionine; Solvents; Spectrometry, Fluorescence; Trypsin; Tryptophan | 1998 |
Effects of long-term parenteral administration of vitamin B6 on B6 status and some aspects of the glucose and protein metabolism of early-weaned piglets.
Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Body Composition; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Male; Pyridoxal Phosphate; Pyridoxine; Swine; Tryptophan; Weaning; Weight Gain | 2001 |
Unfolding of pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase probed by time-resolved tryptophan fluorescence.
Topics: Circular Dichroism; Cysteine Synthase; Models, Molecular; Protein Conformation; Protein Folding; Pyridoxal Phosphate; Spectrometry, Fluorescence; Thermodynamics; Tryptophan | 2002 |
Pyridoxal phosphate and tryptophan metabolism in alloxan-diabetic rats.
Topics: Alloxan; Animals; Coenzymes; Diabetes Mellitus, Experimental; Pyridoxal Phosphate; Rats; Tryptophan | 1960 |
[THE EFFECT OF ULTRASONICS ON TRYPTOPHANASE FROM ESCHERICHIA COLI].
Topics: Escherichia coli; Lyases; Pyridoxal Phosphate; Tryptophan; Ultrasonics | 1963 |
CHARACTERISTICS OF THE INHIBITION OF AROMATIC L-AMINO ACID DECARBOXYLASE BY ALPHA-METHYLAMINO ACIDS.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Carboxy-Lyases; Dihydroxyphenylalanine; Enzyme Inhibitors; Guinea Pigs; Kidney; Pharmacology; Pyridoxal Phosphate; Research; Serotonin; Tryptophan | 1963 |
EXCRETION OF TRYPTOPHAN METABOLITES IN DIFFERENT FORMS OF HAEMOBLASTOSIS.
Topics: Cortisone; Cyclophosphamide; Genetic Diseases, X-Linked; Hodgkin Disease; Humans; Kynurenic Acid; Kynurenine; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphatic Diseases; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Multiple Myeloma; ortho-Aminobenzoates; Phenylbutazone; Polycythemia Vera; Proteins; Pyridoxal Phosphate; Pyridoxine; Sarcoma; Severe Combined Immunodeficiency; Tryptophan; Urine; Xanthurenates | 1964 |
A ROLE FOR PEROXIDASE IN BIOSYNTHESIS OF AUXIN.
Topics: Amides; Carbon Isotopes; Chromatography; Indoleacetic Acids; Metabolism; Peroxidase; Peroxidases; Plant Growth Regulators; Pyridoxal Phosphate; Research; Tryptophan | 1964 |
[ACTIVITY OF AMINOXY- AND HYDROXYLAMINO-ANALOGUES OF PHENYLALANINE AND OF GLYCINE ON SOME PYRIDOXAL PHOSPHATE-DEPENDENT ENZYMATIC REACTIONS].
Topics: Aspartate Aminotransferases; Dopa Decarboxylase; Glycine; Kidney; Liver; Metabolism; Pharmacology; Phenylalanine; Pyridoxal Phosphate; Rats; Research; Tryptophan | 1964 |
A STUDY OF THE PURIFICATION AND PROPERTIES OF TRYPTOPHAN SYNTHETASE OF BENGAL GRAM (CICER ARIETINUM).
Topics: Chemistry Techniques, Analytical; Cicer; Enzyme Inhibitors; Indoles; Isoniazid; Ligases; Penicillamine; Plants; Propionates; Pyridoxal Phosphate; Research; Serine; Tryptophan; Tryptophan Synthase | 1964 |
CATALYTIC PROPERTIES OF TRYPTOPHANASE, A MULTIFUNCTIONAL PYRIDOXAL PHOSPHATE ENZYME.
Topics: Aminohydrolases; Ammonia; Animals; Catalysis; Cattle; Cysteine; Electrophoresis; Escherichia coli; Indoles; Leuconostoc; Manometry; Multifunctional Enzymes; Mutation; Potassium; Pyridoxal Phosphate; Pyruvates; Research; Serine; Serum Albumin; Serum Albumin, Bovine; Tryptophan | 1964 |
SERINE DEAMINATION BY THE B PROTEIN OF ESCHERICHIA COLI TRYPTOPHAN SYNTHETASE.
Topics: Bacterial Proteins; Chromatography; Deamination; Electrophoresis; Enzyme Inhibitors; Escherichia coli; Glycerophosphates; Hydro-Lyases; Indoles; Ligases; Membrane Glycoproteins; Oxidoreductases; Pyridoxal Phosphate; Research; Serine; Spectrophotometry; Threonine; Tryptophan; Tryptophan Synthase | 1964 |
[CLINICAL STUDIES ON THE SECRETION OF INDOLEACETIC ACID IN URINE IN CHILDREN. II. UNDER VARIOUS CONDITIONS].
Topics: Adolescent; Biomedical Research; Body Fluids; Child; Chloramphenicol; Humans; Indoleacetic Acids; Pharmacology; Pyridoxal Phosphate; Tryptophan; Urine | 1964 |
THYROTOXIC MYOPATHY AND VITAMIN B 6 METABOLISM. REPORT OF A CASE WITH HYPERTHYREOIDISM AND PERIODIC PARALYSIS.
Topics: Humans; Hyperthyroidism; Metabolism; Muscular Diseases; Paralyses, Familial Periodic; Paralysis; Pyridoxal Phosphate; Pyridoxine; Tryptophan | 1964 |
THE ROLE OF PYRIDOXAL PHOSPHATE IN THE ALDOLYTIC ACTIVITY OF TRYPTOPHAN SYNTHETASE FROM NEUROSPORA CRASSA.
Topics: Amino Acids; Glycerophosphates; Hydro-Lyases; Mutation; Neurospora; Neurospora crassa; Phosphates; Pyridoxal Phosphate; Pyridoxine; Research; Tryptophan; Tryptophan Synthase | 1964 |
PROPERTIES OF CRYSTALLINE TRYPTOPHANASE.
Topics: Amino Acids; Catalysis; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Crystallization; Escherichia coli; Indoles; Lyases; Pyridoxal Phosphate; Research; Spectrum Analysis; Tryptophan; Ultracentrifugation | 1965 |
Prognostic value of tryptophan load test followed by serum kynurenine determination. Its comparison with pyridoxal-5-phosphate, kynurenine, homocysteine and neopterin amounts.
Topics: Biomarkers; Case-Control Studies; Coronary Disease; Homocysteine; Humans; Kynurenine; Neopterin; Prognosis; Pyridoxal Phosphate; Tryptophan | 2003 |
Hydrostatic pressure affects the conformational equilibrium of Salmonella typhimurium tryptophan synthase.
Topics: Bacterial Proteins; Hydrostatic Pressure; Imines; Kinetics; Protein Conformation; Pyridoxal Phosphate; Salmonella typhimurium; Serine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Tryptophan Synthase | 2005 |
Age-related alterations of B-group vitamin contents in urine, blood and liver from rats.
Topics: Age Factors; Aging; Animals; Biotin; Body Weight; Eating; Folic Acid; Liver; Male; Models, Animal; Niacinamide; Pyridoxal Phosphate; Rats; Tryptophan; Vitamin B 12; Vitamin B Complex | 2008 |
The activity of pyridoxal phosphate in tryptophane formation by cell-free enzyme preparations.
Topics: Enzymes; Pyridoxal Phosphate; Tryptophan | 1946 |
Role of conserved active site tryptophan-101 in functional activity and stability of phosphoserine aminotransferase from an enteric human parasite.
Topics: Amino Acid Sequence; Catalytic Domain; Entamoeba histolytica; Enzyme Stability; Fluorescence Resonance Energy Transfer; Humans; Models, Molecular; Molecular Dynamics Simulation; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Structure, Secondary; Pyridoxal Phosphate; Sequence Alignment; Structure-Activity Relationship; Transaminases; Tryptophan | 2012 |
Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Arabidopsis; Arabidopsis Proteins; Ethylenes; Indoleacetic Acids; Indoles; Methionine; Molecular Sequence Data; Mutation; Pyridoxal Phosphate; Transaminases; Tryptophan | 2013 |
Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and women.
Topics: Adult; Biomarkers; Creatine; Cystathionine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Multivariate Analysis; Postprandial Period; Pyridoxal Phosphate; Serine; Tryptophan; Vitamin B 6; Vitamin B 6 Deficiency; Young Adult | 2013 |
Characterization of tryptophan aminotransferase 1 of Malassezia furfur, the key enzyme in the production of indolic compounds by M. furfur.
Topics: Aminooxyacetic Acid; Cloning, Molecular; Cycloserine; Escherichia coli; Fungal Proteins; Humans; Indoles; Keto Acids; Malassezia; Pigmentation; Pigments, Biological; Pyridoxal Phosphate; Recombinant Proteins; Skin; Tinea Versicolor; Tryptophan; Tryptophan Transaminase | 2013 |
Evidence for increased catabolism of vitamin B-6 during systemic inflammation.
Topics: Aged; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Dietary Supplements; Female; Humans; Inflammation; Kynurenine; Linear Models; Longitudinal Studies; Male; Middle Aged; Neopterin; Norway; Oxidative Stress; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; ROC Curve; Tryptophan; Vitamin B 6 | 2014 |
Vitamins B2 and B6 as determinants of kynurenines and related markers of interferon-γ-mediated immune activation in the community-based Hordaland Health Study.
Topics: Aged; Biomarkers; Cohort Studies; Diet; Female; Humans; Immunity; Interferon-gamma; Kynurenine; Male; Middle Aged; Neopterin; Norway; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Surveys and Questionnaires; Tryptophan; Vitamin B 6 | 2014 |
Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Arginine; Biomarkers; Dietary Supplements; Female; Healthy Volunteers; Humans; Kynurenic Acid; Kynurenine; Life Style; Male; Methionine; ortho-Aminobenzoates; Pyridoxal Phosphate; Sex Factors; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Xanthurenates; Young Adult | 2015 |
Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Male; Metformin; Middle Aged; Prediabetic State; Pyridoxal Phosphate; Stress, Physiological; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult | 2015 |
A structural view of the dissociation of Escherichia coli tryptophanase.
Topics: Bacterial Proteins; Binding Sites; Biocatalysis; Crystallography, X-Ray; Escherichia coli; Gene Expression; Kinetics; Models, Molecular; Mutation; Protein Binding; Protein Multimerization; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Proteus vulgaris; Pyridoxal Phosphate; Recombinant Proteins; Species Specificity; Structural Homology, Protein; Tryptophan; Tryptophanase | 2015 |
Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Female; Humans; Inflammation; Interleukin-10; Kynurenine; Linear Models; Male; Neopterin; ortho-Aminobenzoates; Pyridoxal Phosphate; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Young Adult | 2016 |
Catalytically impaired TrpA subunit of tryptophan synthase from Chlamydia trachomatis is an allosteric regulator of TrpB.
Topics: Allosteric Regulation; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biocatalysis; Catalytic Domain; Chlamydia trachomatis; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Genetic Vectors; Kinetics; Models, Molecular; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Subunits; Pyridoxal Phosphate; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tryptophan Synthase | 2021 |