tryptophan and probenecid

tryptophan has been researched along with probenecid in 91 studies

Research

Studies (91)

Timeframe	Studies, this research(%)	All Research%
pre-1990	85 (93.41)	18.7374
1990's	1 (1.10)	18.2507
2000's	2 (2.20)	29.6817
2010's	3 (3.30)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Bellman, K; Knegtel, RM; Settimo, L	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fuller, RW; Steinberg, M	1
Callaghan, N; Curzon, G; Kantamaneni, BD; Murnaghan, D; Sullivan, PA	1
Moussaoui, D	1
Korf, J; Sebens, JB; van Wijk, M	1
Breese, GR; Cooper, BR; Hollister, AS; Kuhn, CM; Schanberg, SM	1
Beck, O; Sedvall, G; Wiesel, FA	1
Jenner, P; Marsden, CD; Pratt, J; Reynolds, EH	1
Cramer, H; Goodwin, FK; Post, RM	1
MacMillan, V	1
Ahtee, L; Carlsson, A	1
Dunner, DL; Heiber, S; Perel, JM	1
Bowers, MB; Heninger, GR	1
Dunner, DL; Fieve, RR; Gross, HA; Lafleur, D; Meltzer, HL	1
Baker, PC; Buda, RE; Hoff, KM	1
Dakshinamurti, K; Havlicek, V; Herchl, R; LeBlancq, WD	1
Curzon, G; Marsden, CA	1
Paoletti, R; Sirtori, C; Spano, PF	1
Frazer, A; Mendels, J	1
Friedman, E; Gershon, S; Rotrosen, J	1
Aronoff, A; Feldmuller, F; Lal, S; Martin, JB; Sourkes, TL; Young, SN	1
Curzon, G; Hutson, PH; Kantamaneni, BD; Sahakian, BJ; Sarna, GS	1
Carassale, GL; Carlà, V; Cortesini, C; Lombardi, G; Moroni, F; Pellegrini, D	1
Curzon, G; Dourish, CT; Hutson, PH; Sahakian, BJ; Sarna, GS	1
Poddar, MK; Ray, SK	1
Fujiwara, M; Lee, K; Miwa, S	1
Chiang, CY; Xiang, XK	1
Cupo, MA; Donaldson, WE	1
Bednar, I; Forsberg, G; Qureshi, GA; Södersten, P	1
Carlà, V; Moroni, F; Russi, P	1
Borisenko, SA	1
Gerner, RH; Ninan, PT; van Kammen, DP	1
Beni, M; Carlà, V; Lombardi, G; Moroni, F; Russi, P	1
Hayaishi, O; Miwa, S; Watanabe, Y	1
Carlsson, A; Davis, JN	1
Bourgoin, S; Glowinski, J; Hamon, M; Ley, JP; Morot-Gaudry, Y	1
Lewander, T; Sjöström, R	1
Bédard, P; Carlsson, A; Lindqvist, M	1
Goodwin, FK; Post, RM	2
Garelis, E; Lal, S; Sourkes, TL; Young, SN	1
Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P	1
Forn, J; Gessa, GL; Krishna, G; Perez-Cruet, J; Tagliamonte, A; Tagliamonte, P	1
Bowers, MB	3
Bensinger, RE; Klein, DC; Lovenberg, W; Weller, JL	1
Dunner, DL; Goodwin, FK	1
Baker, M; Bunney, WE; Goodwin, FK; Kotin, J; Miller, H; Murphy, DL	1
Curzon, G; Knott, PJ; Marsden, CA	1
McKean, CM	1
Bruinvels, J	1
Buxbaum, DM; Sanders-Busch, E; Yarbrough, GG	1
Chan, YL; Huang, KC	1
Buxbaum, DM; Sanders-Bush, E; Yarbrough, GG	1
Dols, LC; Flentge, F; Korf, J; Schut, T; van Praag, HM	1
Fodor, A; Karczag, I; Molnár, G; Szilágyi, A; Ujvárosi, I	1
Schubert, J	1
Fuller, RW; Snoddy, HD	1
van Praag, HM	2
Costa, E; Lin, RC; Neff, NH; Ngai, SH	1
Forn, J	1
Korf, J; Sebens, JB; Van Praag, HM	1
Bloom, FE; Costa, E	1
Costa, E; Diaz, PM; Ngai, SH	1
Sanders-Bush, E; Sulser, F	1
Curzon, G; Green, AR	1
Costa, E; Lin, RC; Neff, NH; Ngai, SH; Wang, CT	1
Huang, KC; Williams, WM	1
Hook, JB; Moore, KE	1
Downer, RG; Sloley, BD	1
Anderson, GM; Gauthier, S; Purdy, WC; Young, SN	1
Deanović, Z; Jamnicky, B; Mück-Seler, D	1
Hedner, T; Lundborg, P	1
Buda, M; Cespuglio, R; Faradji, H; Gonon, F; Jouvet, M; Pujol, JF; Riou, F	1
Buda, M; Cespuglio, R; Faradji, H; Gonon, F; Jouvet, M; Ponchon, JL; Pujol, JF; Riou, F	1
Anderson, GH; Leprohon, CE	1
Joseph, MH; Kennett, GA	2
Moore, KE; Nielsen, JA	1
Korf, J; van den Burg, W; van den Hoofdakker, RH	1
Buchle, AM; Fehr, B; Feldtrauer, JJ; Stoecklin, K; Waldmeier, PC	1
Dunner, DL; Fieve, RR; Goodnick, PJ; Perel, JM	1
Johnston, CA; Moore, KE	1
Bachmann, C; Colombo, JP	1
Diksic, M; Grdisa, M; Tsuiki, K; Vanier, M; Worsley, K	1
Carlà, V; Cavone, L; Cosi, C; Cozzi, A; Mannaioni, G; Maratea, D; Moroni, F; Sili, M	1

Reviews

6 review(s) available for tryptophan and probenecid

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Regulation of enzymes that synthesize neurotransmitter monoamines. Advances in enzyme regulation, 1976, Volume: 14 Topics: Aminophylline; Animals; Brain; Catecholamines; Dopamine; Epinephrine; Ganglia; Hexamethonium Compounds; Hydroxyindoleacetic Acid; Methiothepin; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Norepinephrine; Papaverine; Pargyline; Probenecid; Quinolines; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase	1976
[Biochemistry of depression. Literature analysis]. L'Encephale, 1978, Volume: 4, Issue:3 Topics: Adrenal Cortex Hormones; Animals; Antidepressive Agents, Tricyclic; Brain; Depression; Dopamine; Humans; Lithium; Monoamine Oxidase Inhibitors; Neurotransmitter Agents; Norepinephrine; Probenecid; Reserpine; Serotonin; Synapses; Thyroid Hormones; Tryptophan; Water-Electrolyte Imbalance	1978
Clinical relevance of drugs affecting tryptophan transport. Annual review of pharmacology, 1975, Volume: 15 Topics: Anti-Inflammatory Agents; Biological Transport; Clofibrate; Contraceptives, Oral; Female; Humans; Probenecid; Time Factors; Tryptophan	1975
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies. Brain research, 1974, Oct-11, Volume: 79, Issue:1 Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroid Plexus; Dihydroxyphenylalanine; Dogs; Dopamine; Fenclonine; Glycols; Haplorhini; Homovanillic Acid; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Probenecid; Serotonin; Spinal Cord; Spinal Cord Injuries; Tryptophan	1974
Turnover rate measurements of brain serotonin in unanesthetized rats. Advances in biochemical psychopharmacology, 1969, Volume: 1 Topics: Animals; Brain; Carbon Isotopes; Hydroxyindoleacetic Acid; Hydroxylation; Methods; Monoamine Oxidase Inhibitors; Pineal Gland; Probenecid; Rats; Serotonin; Tryptophan	1969

Trials

5 trial(s) available for tryptophan and probenecid

Article	Year
The effect of L-tryptophan administration on the concentration of probenecid in plasma and cerebrospinal fluid in patients. Psychopharmacology, 1977, Aug-16, Volume: 53, Issue:3 Topics: Adult; Aged; Blood Proteins; Drug Interactions; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Protein Binding; Tryptophan	1977
Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid. Psychotherapy and psychosomatics, 1974, Volume: 23, Issue:1-6 Topics: Bipolar Disorder; Brain; Depression; Dihydroxyphenylalanine; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methyltyrosines; Phenylacetates; Placebos; Probenecid; Stimulation, Chemical; Substance-Related Disorders; Tryptophan	1974
Effect of L-tryptophan on brain serotonin metabolism in depressed patients. Archives of general psychiatry, 1972, Volume: 26, Issue:4 Topics: Brain; Brain Chemistry; Clinical Trials as Topic; Depression; Evaluation Studies as Topic; Humans; Hydroxyindoleacetic Acid; Placebos; Probenecid; Serotonin; Spinal Puncture; Tryptophan	1972
Amitriptyline in man: decreased formation of central 5-hydroxyindoleacetic acid. Clinical pharmacology and therapeutics, 1974, Volume: 15, Issue:2 Topics: Aged; Amitriptyline; Clinical Trials as Topic; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Psychiatric Status Rating Scales; Serotonin; Tryptophan	1974
L-tryptophan in affective disorders: indoleamine changes and differential clinical effects. Psychopharmacologia, 1974, Jan-09, Volume: 34, Issue:1 Topics: Affective Symptoms; Blood Platelets; Clinical Trials as Topic; Depression; Humans; Hydroxyindoleacetic Acid; Indoles; Obsessive-Compulsive Disorder; Placebos; Probenecid; Serotonin; Sleep; Tryptophan	1974

Other Studies

80 other study(ies) available for tryptophan and probenecid

Article	Year
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Cerebral transmitter precursors and metabolites in advanced renal disease. Journal of neurology, neurosurgery, and psychiatry, 1978, Volume: 41, Issue:7 Topics: Adult; Aged; Brain; Brain Diseases; Fatty Acids, Nonesterified; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neurotransmitter Agents; Probenecid; Serum Albumin; Sex Factors; Tryptophan; Tyrosine; Uremia	1978
Probenecid-induced increase of 5-hydroxytryptamine synthesis in rat brain, as measured by formation of 5-hydroxytryptophan. Psychopharmacology, 1979, Feb-28, Volume: 60, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Benserazide; Blood-Brain Barrier; Brain; Brain Chemistry; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Male; Probenecid; Rats; Serotonin; Stimulation, Chemical; Time Factors; Tryptophan	1979
An inhibitory role for brain serotonin-containing systems in the locomotor effects of d-amphetamine. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:1 Topics: Animals; Brain; Catecholamines; Dextroamphetamine; Diet; Fenclonine; Food Deprivation; Hydroxyindoleacetic Acid; Male; Motor Activity; Pargyline; Probenecid; Rats; Serotonin; Stimulation, Chemical; Tryptophan	1976
Mass fragmentographic determination of 5-hydroxytryptamine and 5-hydroxyindole-3-acetic acid in brain tissue using deuterated internal standards. Journal of chromatography, 1977, Apr-11, Volume: 134, Issue:2 Topics: Animals; Brain; Brain Chemistry; Deuterium; Fenclonine; Gas Chromatography-Mass Spectrometry; Hydroxyindoleacetic Acid; Male; Microchemistry; Pargyline; Probenecid; Rats; Reserpine; Serotonin; Tryptophan	1977
Clonazepam induces decreased serotoninergic activity in the mouse brain. Neuropharmacology, 1979, Volume: 18, Issue:10 Topics: Animals; Benzodiazepinones; Brain Chemistry; Clonazepam; Fenclonine; Hydroxyindoleacetic Acid; Male; Mice; Probenecid; Serotonin; Time Factors; Tranylcypromine; Tryptophan	1979
Cyclic AMP in cerebrospinal fluid of manic and depressive patients. Psychological medicine, 1977, Volume: 7, Issue:4 Topics: Administration, Oral; Amitriptyline; Bipolar Disorder; Cyclic AMP; Depression; Humans; Imipramine; Lithium; Methadone; Methyltyrosines; Physical Exertion; Probenecid; Tryptophan	1977
The effects of acute hypercapnia on cerebral indole amine metabolism. Canadian journal of physiology and pharmacology, 1978, Volume: 56, Issue:2 Topics: 5-Hydroxytryptophan; Amines; Animals; Brain; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Hypercapnia; Indoles; Male; Pargyline; Probenecid; Rats; Serotonin; Tryptophan	1978
Dual action of methadone on 5-HT synthesis and metabolism. Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 307, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Hydroxyindoleacetic Acid; Male; Methadone; Morphine; Naloxone; Probenecid; Rats; Serotonin; Tryptophan; Tyrosine	1979
Lithium: clinical effects and cerebrospinal fluid acid monoamine metabolites. Communications in psychopharmacology, 1977, Volume: 1, Issue:2 Topics: Adult; Affective Symptoms; Aged; Biogenic Amines; Bipolar Disorder; Depression; Electroencephalography; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lithium; Male; Middle Aged; Probenecid; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan	1977
Prostaglandin F in patients with primary affective disorder. Biological psychiatry, 1977, Volume: 12, Issue:3 Topics: Adult; Aged; Bipolar Disorder; Depression; Female; Humans; Male; Middle Aged; Probenecid; Prostaglandins F; Tryptophan	1977
Precursor and end product effects upon indoleamine maturation in mouse brain. Biology of the neonate, 1976, Volume: 29, Issue:5-6 Topics: Age Factors; Animals; Brain; Hydroxyindoleacetic Acid; Mice; Probenecid; Serotonin; Tryptophan	1976
Nonparallel changes in brain monoamines of pyridoxine-deficient growing rats. Experimental brain research, 1976, Nov-23, Volume: 26, Issue:4 Topics: Animals; Animals, Newborn; Body Weight; Brain; Brain Stem; Dopamine; Hydroxyindoleacetic Acid; Norepinephrine; Organ Size; Pargyline; Probenecid; Pyridoxine; Rats; Serotonin; Time Factors; Tryptophan; Tryptophan Hydroxylase; Vitamin B 6 Deficiency	1976
Effects of altered brain 5-hydroxytryptaminergic activity on brain tryptophan, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid. Neuropharmacology, 1976, Volume: 15, Issue:11 Topics: Animals; Body Weight; Brain; Brain Chemistry; Brain Stem; Electric Stimulation; Electrolysis; Hot Temperature; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Male; Probenecid; Rats; Serotonin; Tryptophan	1976
Reduced central serotonergic activity in mania: implications for the relationship between depression and mania. The British journal of psychiatry : the journal of mental science, 1975, Volume: 126 Topics: Bipolar Disorder; Brain; Depression; Disease Models, Animal; Humans; Hydroxyindoleacetic Acid; Hypnotics and Sedatives; Imipramine; Lithium; Methysergide; Monoamine Oxidase Inhibitors; Phenylalanine; Probenecid; Serotonin; Tryptophan	1975
Effects of acute cocaine treatment on the turnover of 5-hydroxytryptamine in the rat brain. British journal of pharmacology, 1975, Volume: 54, Issue:1 Topics: Amphetamine; Animals; Behavior, Animal; Brain; Brain Chemistry; Cocaine; Depression, Chemical; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Pargyline; Probenecid; Rats; Serotonin; Tryptophan	1975
Relationships between tryptophan in serum and CSF, and 5-hydroxyindoleacetic acid in CSF of man: effect of cirrhosis of liver and probenecid administration. Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:4 Topics: Adult; Biological Transport; Female; Hepatic Encephalopathy; Humans; Hydroxyindoleacetic Acid; Liver Cirrhosis; Male; Middle Aged; Probenecid; Serum Albumin; Sex Factors; Tryptophan	1975
3,4-Dihydroxyphenylethylamine and 5-hydroxytryptamine metabolism in the rat: acidic metabolites in cisternal cerebrospinal fluid before and after giving probenecid. Journal of neurochemistry, 1985, Volume: 45, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan	1985
Content of quinolinic acid and of other tryptophan metabolites increases in brain regions of rats used as experimental models of hepatic encephalopathy. Journal of neurochemistry, 1986, Volume: 46, Issue:3 Topics: Acetates; Animals; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Disease Models, Animal; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Male; Portacaval Shunt, Surgical; Probenecid; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Serotonin; Tryptophan	1986
Monitoring 5HT metabolism in the brain of the freely moving rat. Annals of the New York Academy of Sciences, 1986, Volume: 473 Topics: Animals; Brain; Dialysis; Eating; Hydroxyindoleacetic Acid; Hypothalamus; Kinetics; Male; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Social Behavior; Tryptophan	1986
Pentylenetetrazol: effect on carbaryl-induced changes of serotonin metabolism in pons-medulla of rat brain. Bioscience reports, 1986, Volume: 6, Issue:8 Topics: Animals; Carbaryl; Hydroxyindoleacetic Acid; Medulla Oblongata; Pargyline; Pentylenetetrazole; Pons; Probenecid; Rats; Serotonin; Tryptophan	1986
Determination of serotonin turnover in the rat brain using 6-fluorotryptophan. Journal of neurochemistry, 1987, Volume: 48, Issue:5 Topics: Animals; Brain; Hydroxyindoleacetic Acid; Hypoxia; Male; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tryptophan Hydroxylase	1987
Does morphine enhance the release of 5-hydroxytryptamine in the rat spinal cord? An in vivo differential pulse voltammetry study. Brain research, 1987, May-19, Volume: 411, Issue:2 Topics: Animals; Electrochemistry; Hydroxyindoleacetic Acid; Male; Morphine; Probenecid; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Stereoisomerism; Tryptophan; Urate Oxidase	1987
Effects of lead and niacin on tryptophan and serotonin metabolism. Drug-nutrient interactions, 1988, Volume: 5, Issue:4 Topics: Animals; Brain; Brain Chemistry; Chickens; Diet; Harmaline; Hydroxyindoleacetic Acid; Lead; Lead Poisoning; Liver; Male; Monoamine Oxidase; Niacin; Probenecid; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tryptophan Oxygenase	1988
Tryptophan, 5-HTP, 5-HT and 5-HIAA in the cerebrospinal fluid and sexual behavior in male rats. Neuroscience letters, 1989, Feb-13, Volume: 97, Issue:1-2 Topics: 5-Hydroxytryptophan; Animals; Fenclonine; Homovanillic Acid; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Sexual Behavior, Animal; Tryptophan	1989
Indolpyruvic acid administration increases the brain content of kynurenic acid. Is this a new avenue to modulate excitatory amino acid receptors in vivo? Biochemical pharmacology, 1989, Aug-01, Volume: 38, Issue:15 Topics: Animals; Brain; Indoles; Kidney; Kynurenic Acid; Liver; Male; Myocardium; Probenecid; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Tryptophan	1989
[Effect of ethanol and probenecid on the excretory function of the cerebral choroid plexus in rats]. Biulleten' eksperimental'noi biologii i meditsiny, 1989, Volume: 107, Issue:3 Topics: Animals; Carbon Radioisotopes; Choroid Plexus; Dose-Response Relationship, Drug; Ethanol; Levodopa; Male; Probenecid; Rats; Rats, Inbred Strains; Time Factors; Tryptophan; Tyrosine	1989
Cerebrospinal fluid cholecystokinin, bombesin and somatostatin in schizophrenia and normals. Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:1 Topics: Adolescent; Adult; Bombesin; Cholecystokinin; Female; Humans; Hydrocortisone; Male; Middle Aged; Peptides; Pimozide; Probenecid; Schizophrenia; Somatostatin; Tryptophan	1985
Presence of kynurenic acid in the mammalian brain. Journal of neurochemistry, 1988, Volume: 51, Issue:1 Topics: Animals; Brain; Brain Chemistry; Brain Stem; Chromatography, High Pressure Liquid; Corpus Striatum; Frontal Lobe; Guinea Pigs; Hippocampus; Humans; Kynurenic Acid; Mice; Probenecid; Rabbits; Rats; Tissue Distribution; Tryptophan	1988
6R-L-erythro-5,6,7,8-tetrahydrobiopterin as a regulator of dopamine and serotonin biosynthesis in the rat brain. Archives of biochemistry and biophysics, 1985, May-15, Volume: 239, Issue:1 Topics: Animals; Biopterins; Brain; Dopamine; Hydroxylation; Isomerism; Probenecid; Pteridines; Rats; Serotonin; Time Factors; Tryptophan; Tyrosine	1985
The effect of hypoxia on monoamine synthesis, levels and metabolism in rat brain. Journal of neurochemistry, 1973, Volume: 21, Issue:4 Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Fluorometry; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypoxia; Kinetics; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Probenecid; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase	1973
Estimation of the rate of 5-HT synthesis in the mouse brain by various methods. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:3 Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Benzyl Compounds; Brain; Brain Chemistry; Carboxy-Lyases; Chromatography, Ion Exchange; Female; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Mice; Monoamine Oxidase Inhibitors; Pargyline; Probenecid; Serotonin; Spectrometry, Fluorescence; Tritium; Tryptophan	1974
Increase in the plasma concentration of free tryptophan caused by probenecid in humans. Psychopharmacologia, 1973, Oct-23, Volume: 33, Issue:1 Topics: Aged; Brain; Enteral Nutrition; Female; Humans; Hydroxyindoleacetic Acid; Probenecid; Serotonin; Tryptophan	1973
Effect of a transverse cerebral hemisection on 5-hydroxytryptamine metabolism in the rat brain. Naunyn-Schmiedeberg's archives of pharmacology, 1972, Volume: 272, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carboxy-Lyases; Diencephalon; Female; Hydrazines; Hydroxyindoleacetic Acid; Male; Mesencephalon; Monoamine Oxidase Inhibitors; Pargyline; Probenecid; Rats; Serotonin; Time Factors; Tryptophan	1972
Brain serotonin, affective illness, and antidepressant drugs: cerebrospinal fluid studies with probenecid. Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0 Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Brain; Brain Chemistry; Depression; Fenclonine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Imipramine; Probenecid; Serotonin; Spinal Puncture; Time Factors; Tryptophan	1974
Effect of psychotropic drugs on tryptophan concentration in the rat brain. The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3 Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine	1971
Stimulation of brain serotonin synthesis by dibutyryl-cyclic AMP in rats. Journal of neurochemistry, 1971, Volume: 18, Issue:7 Topics: Adenine Nucleotides; Animals; Brain; Brain Chemistry; Cerebral Ventricles; Cyclic AMP; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Probenecid; Rats; Serotonin; Stimulation, Chemical; Tryptophan; Tyrosine	1971
Fluorometric measurement of 5-hydroxyindoleacetic acid (5HIAA) and tryptophan in human CSF: effects of high doses of probenecid. Biological psychiatry, 1974, Volume: 9, Issue:1 Topics: Administration, Oral; Adolescent; Adult; Bipolar Disorder; Brain Chemistry; Depression; Female; Fluorometry; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Schizophrenia; Tryptophan	1974
Radiometric assay of total tryptophan hydroxylation by intact cultured pineal glands. Journal of neurochemistry, 1974, Volume: 23, Issue:1 Topics: 5-Hydroxytryptophan; Animals; Chromatography, Ion Exchange; Cycloheximide; Evaluation Studies as Topic; Female; Isoproterenol; Kinetics; Male; Melatonin; Mescaline; Methods; Mixed Function Oxygenases; Organ Culture Techniques; Phenylalanine; Pineal Gland; Probenecid; Rats; Serotonin; Species Specificity; Time Factors; Tritium; Tryptophan; Tryptophan Hydroxylase	1974
Comparative studies of brain 5-hydroxytryptamine and tryptamine. Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0 Topics: Animals; Brain; Brain Chemistry; Cerebellum; Cerebral Cortex; Corpus Striatum; Food Deprivation; Hydroxyindoleacetic Acid; Hypothalamus; Male; Medulla Oblongata; Mesencephalon; Pons; Probenecid; Rats; Serotonin; Stereotaxic Techniques; Tryptamines; Tryptophan	1974
The effects of high phenylalanine concentrations on serotonin and catecholamine metabolism in the human brain. Brain research, 1972, Dec-12, Volume: 47, Issue:2 Topics: Adolescent; Adult; Amino Acids; Brain; Catecholamines; Chromatography; Dopamine; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Phenylacetates; Phenylalanine; Phenylketonurias; Probenecid; Serotonin; Tryptophan; Tyrosine	1972
Inhibition of the biosynthesis of 5-hydroxytryptamine in rat brain by imipramine. European journal of pharmacology, 1972, Volume: 20, Issue:2 Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Fluorometry; Hydroxyindoleacetic Acid; Imipramine; Kinetics; Male; Probenecid; Rats; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Synaptosomes; Time Factors; Tryptophan	1972
Increased serotonin turnover in acutely morphine-treated mice. Biochemical pharmacology, 1972, Oct-01, Volume: 21, Issue:19 Topics: Animals; Brain Chemistry; Cerebral Cortex; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; Morphine; Probenecid; Serotonin; Time Factors; Tritium; Tryptophan	1972
Renal excretion of D-tryptophan, 5-hydroxytryptamine, and 5-hydroxyindoleacetic acid in rats. The American journal of physiology, 1973, Volume: 224, Issue:1 Topics: Absorption; Animals; Biological Transport; Carbon Isotopes; Depression, Chemical; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Kidney Function Tests; Kidney Tubules; Kidney Tubules, Distal; Kidney Tubules, Proximal; Perfusion; Probenecid; Punctures; Rats; Serotonin; Tryptophan	1973
Biogenic amines and narcotic effects. II. Serotonin turnover in the rat after acute and chronic morphine administration. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:2 Topics: Animals; Brain Chemistry; Drug Tolerance; Hydroxyindoleacetic Acid; Male; Morphine; Motor Activity; Naloxone; Pargyline; Probenecid; Rats; Serotonin; Time Factors; Tritium; Tryptophan; Tryptophan Hydroxylase	1973
The influence of probenecid on the metabolism of serotonin, dopamine and their precursors in man. Psychopharmacologia, 1973, Volume: 33, Issue:2 Topics: Adult; Aged; Amino Acids; Brain; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Serotonin; Time Factors; Tryptophan; Tyrosine	1973
5-Hydroxyindoleacetic acid in cerebrospinal fluid. Acta medica Academiae Scientiarum Hungaricae, 1973, Volume: 30, Issue:3 Topics: Adult; Age Factors; Brain Diseases; Brain Stem; Depression; Epilepsy; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Middle Aged; Neurocognitive Disorders; Paralysis; Parkinson Disease; Probenecid; Spectrometry, Fluorescence; Spinal Cord Compression; Tabes Dorsalis; Tryptophan	1973
Labelled 5-hydroxytryptamine and 5-hydroxyindoleacetic acid formed in vivo from 3H-tryptophan in rat brain effect of probenecid. Acta physiologica Scandinavica, 1974, Volume: 90, Issue:2 Topics: Animals; Brain; Brain Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Depression, Chemical; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Serotonin; Stimulation, Chemical; Tissue Extracts; Tritium; Tryptophan	1974
Long-term effects of 4-chloroamphetamine on brain 5-hydroxyindole metabolism in rats. Neuropharmacology, 1974, Volume: 13, Issue:1 Topics: Amphetamine; Animals; Body Weight; Brain; Brain Chemistry; Chlorine; Depression, Chemical; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Monoamine Oxidase Inhibitors; Organ Size; Probenecid; Rats; Serotonin; Time Factors; Tryptophan	1974
Toward a biochemical classification of depression. Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0 Topics: Antidepressive Agents; Biogenic Amines; Brain; Brain Stem; Depression; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Norepinephrine; Nortriptyline; Probenecid; Receptors, Drug; Serotonin; Sleep Deprivation; Spinal Cord; Suicide; Tryptophan	1974
Active transport of 5-hydroxyindoleacetic acid by the rabbit choroid plexus in vitro. Blockade by probenecid and metabolic inhibitors. Biochemical pharmacology, 1972, Mar-01, Volume: 21, Issue:5 Topics: Aminohippuric Acids; Animals; Biological Transport, Active; Carbon Isotopes; Choroid Plexus; Chromatography, Thin Layer; Depression, Chemical; Ethylmaleimide; Hydroxyindoleacetic Acid; In Vitro Techniques; Iodoacetates; Male; Nitrophenols; Norepinephrine; Osmolar Concentration; Ouabain; Probenecid; Rabbits; Serotonin; Time Factors; Tritium; Tryptophan	1972
Serum tryptophan decreased, brain tryptophan increased and brain serotonin synthesis unchanged after probenecid loading. Brain research, 1972, Jul-13, Volume: 42, Issue:1 Topics: Animals; Brain; Brain Chemistry; Humans; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Serotonin; Tryptophan	1972
The effects of drugs on serotonergic nerve terminals. Advances in cytopharmacology, 1971, Volume: 1 Topics: Animals; Brain; Catecholamines; Cerebellum; Histocytochemistry; Hydroxyindoleacetic Acid; Hydroxylation; Kinetics; Lysergic Acid Diethylamide; Microscopy, Electron; Monoamine Oxidase Inhibitors; Morphine; Nerve Endings; Norepinephrine; Pargyline; Probenecid; Rats; Serotonin; Synapses; Time Factors; Tryptophan	1971
Effect of oxygen on brain serotonin metabolism in rats. The American journal of physiology, 1968, Volume: 214, Issue:3 Topics: 5-Hydroxytryptophan; Animals; Brain; Hydroxyindoleacetic Acid; Kinetics; Male; Mixed Function Oxygenases; Oxygen; Pargyline; Probenecid; Rats; Serotonin; Tryptophan	1968
P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin. The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2 Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Brain; Brain Chemistry; Carbon Isotopes; Chlorine; Hydroxyindoleacetic Acid; Male; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Norepinephrine; Pargyline; Phenylalanine; Probenecid; Quinolizines; Rats; Reserpine; Serotonin; Tritium; Tryptophan	1970
Effects of immobilization on rat liver tryptophan pyrrolase and brain 5-hydroxytryptamine metabolism. British journal of pharmacology, 1969, Volume: 37, Issue:3 Topics: Adrenalectomy; Allopurinol; Animals; Brain; Brain Chemistry; Enzyme Induction; Hydroxyindoleacetic Acid; Immobilization; Liver; Lysergic Acid Diethylamide; Male; Probenecid; Rats; Serotonin; Time Factors; Tryptophan; Tryptophan Oxygenase	1969
In vivo measurement of 5-hydroxytryptamine turnover rate in the rat brain from the conversion of C14-tryptophan to C14-5-hydroxytryptamine. The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:2 Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Drug Contamination; Indoleacetic Acids; Kinetics; Male; Pargyline; Probenecid; Rats; Serotonin; Time Factors; Tryptophan	1969
5-hydroxyindoleacetic acid in the brain and cerebrospinal fluid of the rabbit following administration of drugs affecting 5-hydroxytryptamine. Journal of neurochemistry, 1970, Volume: 17, Issue:6 Topics: Amino Acids; Animals; Brain; Brain Chemistry; Cerebrospinal Fluid; Hydroxyindoleacetic Acid; Iproniazid; Male; Phenylalanine; Probenecid; Rabbits; Reserpine; Serotonin Antagonists; Tryptophan	1970
In vitro and in vivo renal tubular transport of tryptophan derivatives. The American journal of physiology, 1970, Volume: 219, Issue:5 Topics: Aminohippuric Acids; Animals; Chromatography, Thin Layer; Dinitrophenols; Dogs; In Vitro Techniques; Injections, Intra-Arterial; Kidney Tubules; Methods; Phenylalanine; Probenecid; Protein Binding; Rabbits; Temperature; Tryptophan	1970
The renal handling of alpha-methyltyrosine. The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:2 Topics: Animals; Dogs; Histidine; Hydrogen-Ion Concentration; Inulin; Kidney; Male; Methyltyrosines; Probenecid; Protein Binding; Rats; Tryptophan; Urine	1969
Distribution of 5-hydroxytryptamine and indolealkylamine metabolites in the American cockroach, Periplaneta americana L. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 79, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Cockroaches; Dopamine; Ganglia; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Mitochondria; Monoamine Oxidase; Probenecid; Rats; Reserpine; Serotonin; Species Specificity; Succinate Dehydrogenase; Tryptophan	1984
The origin of indoleacetic acid and indolepropionic acid in rat and human cerebrospinal fluid. Journal of neurochemistry, 1980, Volume: 34, Issue:5 Topics: Animals; Blood-Brain Barrier; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Indoles; Male; Monoamine Oxidase Inhibitors; Probenecid; Rats; Serotonin; Tryptamines; Tryptophan	1980
Effect of doxepin on serotonin metabolism in rat brain and serotonin uptake by human blood platelets. Progress in neuro-psychopharmacology, 1980, Volume: 4, Issue:3 Topics: Animals; Blood Platelets; Brain; Doxepin; Female; Humans; Hydroxyindoleacetic Acid; In Vitro Techniques; Pargyline; Probenecid; Rats; Serotonin; Tryptophan	1980
Serotoninergic development in the postnatal rat brain. Journal of neural transmission, 1980, Volume: 49, Issue:4 Topics: 5-Hydroxytryptophan; Age Factors; Animals; Animals, Newborn; Aromatic-L-Amino-Acid Decarboxylases; Benzyl Alcohols; Brain; Clomipramine; Hydrazines; Hydroxyindoleacetic Acid; Probenecid; Rats; Serotonin; Tryptophan	1980
Differential pulse voltammetry in brain tissue. II. Detection of 5-hydroxyindoleacetic acid in the rat striatum. Brain research, 1981, Nov-02, Volume: 223, Issue:2 Topics: 5-Hydroxytryptophan; Animals; Benserazide; Benzyl Alcohols; Clorgyline; Corpus Striatum; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Male; Potentiometry; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tryptophan	1981
In vivo measurements by differential pulse voltammetry of extra-cellular 5-hydroxyindoleacetic acid in the rat brain. Journal de physiologie, 1981, Volume: 77, Issue:2-3 Topics: 5,7-Dihydroxytryptamine; Animals; Brain; Chromatography, High Pressure Liquid; Clorgyline; Corpus Striatum; Hydroxyindoleacetic Acid; Male; Potentiometry; Probenecid; Rats; Reserpine; Tryptophan	1981
Relationships among maternal diet, serotonin metabolism at weaning, and protein selection of progeny. The Journal of nutrition, 1982, Volume: 112, Issue:1 Topics: Animals; Body Weight; Brain; Dietary Proteins; Feeding Behavior; Female; Hydroxyindoleacetic Acid; Male; Pregnancy; Prenatal Exposure Delayed Effects; Probenecid; Rats; Serotonin; Tryptophan; Weaning	1982
In vivo voltammetry in the rat hippocampus as in index of drug effects on extraneuronal 5-HT. Neuropharmacology, 1981, Volume: 20, Issue:12B Topics: Animals; Electrodes, Implanted; Electrophysiology; Fenclonine; Fluoxetine; Hippocampus; Hydroxyindoleacetic Acid; Microelectrodes; p-Chloroamphetamine; Probenecid; Rats; Serotonin; Tryptophan	1981
Measurement of metabolites of dopamine and 5-hydroxytryptamine in cerebroventricular perfusates of unanesthetized, freely-moving rats: selective effects of drugs. Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood-Brain Barrier; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Pargyline; Perfusion; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan	1982
Acid metabolites and precursor amino acids of 5-hydroxytryptamine and dopamine in affective and other psychiatric disorders. Psychiatria clinica, 1983, Volume: 16, Issue:1 Topics: Adjustment Disorders; Adult; Aged; Amino Acids; Bipolar Disorder; Depressive Disorder; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Probenecid; Protein Precursors; Psychomotor Agitation; Psychotic Disorders; Serotonin; Tryptophan; Tyrosine	1983
The effects of amfonelic acid on 5-HT metabolism in rat brain. Journal of neural transmission, 1983, Volume: 57, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Nalidixic Acid; Naphthyridines; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan	1983
CSF AMP in primary affective disorder: effects of probenecid and tryptophan. Biological psychiatry, 1980, Volume: 15, Issue:1 Topics: Bipolar Disorder; Cyclic AMP; Depression; Humans; Probenecid; Tryptophan	1980
Does in vivo voltammetry in the hippocampus measure 5-HT release? Brain research, 1982, Mar-25, Volume: 236, Issue:2 Topics: Animals; Electrophysiology; Fenclonine; Fluoxetine; Hippocampus; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Serotonin; Tryptophan	1982
Measurement of 5-hydroxytryptamine synthesis and metabolism in selected discrete regions of the rat brain using high performance liquid chromatography and electrochemical detection: pharmacological manipulations. Journal of neural transmission, 1983, Volume: 57, Issue:1-2 Topics: Animals; Brain; Corpus Striatum; Hydrazines; Hypothalamus; Male; Pargyline; Probenecid; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tryptophan	1983
Increased tryptophan uptake into the brain in hyperammonemia. Life sciences, 1983, Dec-12, Volume: 33, Issue:24 Topics: Amino Acids; Ammonia; Animals; Brain; Brain Stem; Disease Models, Animal; Indoles; Male; Probenecid; Rats; Rats, Inbred Strains; Tryptophan; Urease	1983
[Central serotonin metabolism in depression]. Nederlands tijdschrift voor geneeskunde, 1980, Jun-14, Volume: 124, Issue:24 Topics: 5-Hydroxytryptophan; Affect; Brain; Depression; Humans; Longitudinal Studies; Probenecid; Serotonin; Tryptophan	1980
Determination of the lumped constant for the alpha-methyltryptophan method of estimating the rate of serotonin synthesis. Journal of neurochemistry, 1995, Volume: 64, Issue:2 Topics: Animals; Autoradiography; Brain; Female; In Vitro Techniques; Models, Neurological; Neurochemistry; Probenecid; Rats; Rats, Wistar; Serotonin; Tissue Distribution; Tryptophan	1995
G-protein coupled receptor 35 (GPR35) activation and inflammatory pain: Studies on the antinociceptive effects of kynurenic acid and zaprinast. Neuropharmacology, 2011, Volume: 60, Issue:7-8 Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Ganglia, Spinal; Gene Expression; Inflammation; Kynurenic Acid; Kynurenine; Male; Mice; Neuroglia; Pain; Pain Measurement; Phosphodiesterase Inhibitors; Probenecid; Purinones; Receptors, G-Protein-Coupled; Spinal Cord; Tryptophan	2011