tryptophan has been researched along with picolinic acid in 42 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (9.52) | 18.7374 |
1990's | 8 (19.05) | 18.2507 |
2000's | 8 (19.05) | 29.6817 |
2010's | 14 (33.33) | 24.3611 |
2020's | 8 (19.05) | 2.80 |
Authors | Studies |
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Bellman, K; Knegtel, RM; Settimo, L | 1 |
Boersma, YL; Dekker, FJ; Dömling, ASS; Eleftheriadis, N; Wójcik, M; Zwinderman, MRH | 1 |
Bottazzi, B; Gusella, GL; Radzioch, D; Varesio, L | 1 |
Blasi, E; Clayton, M; Radzioch, D; Ruffman, R; Varesio, L | 1 |
Beninger, RJ; Boegman, RJ; Jhamandas, K | 1 |
Beninger, RJ; Bialik, M; Boegman, RJ; Jhamandas, K | 1 |
Dykens, JA; Stern, A; Sullivan, SG | 1 |
Shibata, Y; Takeuchi, F; Tsubouchi, R | 1 |
Krieger, I; Statter, M | 1 |
Campione, AL; Doman, DR; van Winkle, LJ | 1 |
Boni, RL; Markey, SP; Naritsin, DB | 1 |
Cox, GW; Melillo, G; Radzioch, D; Varesio, L | 1 |
Goodman, CB; Heyliger, SO; Ngong, JM; Soliman, KF | 1 |
Bosco, MC; Massazza, S; Melillo, G; Rapisarda, A; Varesio, L; Young, H | 1 |
Jirgensons, J; Jurika, E; Rudzite, V | 1 |
Allegri, G; Bertazzo, A; Biasiolo, M; Costa, CV; Ragazzi, E | 1 |
Bwanaisa, L; Day, NP; Hunt, NH; Kayira, K; Medana, IM; Njobvu, A; Salahifar-Sabet, H; Smythe, G; Stocker, R; Taylor, TE; Turner, GD | 1 |
Franklin, M; Odontiadis, J | 1 |
Bosco, MC; Massazza, S; Pastorino, S; Rapisarda, A; Reffo, G; Varesio, L | 1 |
Bruckner, RC; Ferreira, P; Jorns, MS; Zhao, G | 1 |
Kakimi, K; Kubo, K; Motomura, N; Narui, K; Noguchi, N; Saito, A; Sasatsu, M; Takamoto, S | 1 |
Egashira, Y; Sanada, H; Sasaki, N | 1 |
Brew, BJ; Chen, Y; Coggan, S; Cullen, KM; Garner, B; Grant, R; Guillemin, GJ; Meininger, V; Stankovic, R | 1 |
Brew, BJ; Chen, Y; Guillemin, GJ | 1 |
Braidy, N; Chan-Ling, T; Grant, R; Guillemin, GJ; Mansour, H | 1 |
Juturu, V; Komorowski, JR; Orhan, C; Sahin, K; Sahin, N; Tuzcu, M; Ulas, M | 1 |
Blumenthal, A; Britton, WJ; Ehrt, S; Guillemin, GJ; Huch, JH; Nagalingam, G; Saunders, BM; Smythe, GA; Walker, L | 1 |
Buerger, K; Guillemin, GJ; Hampel, H; Schwarz, MJ; Teipel, SJ | 1 |
Banister, SD; Guillemin, GJ; Karl, T; Kassiou, M; Lim, CK; Purves-Tyson, T; Weickert, CS; Zavitsanou, K | 1 |
Adams, S; Braidy, N; Brew, BJ; Bustamante, S; Guillemin, GJ; Lim, CK; McDonald, KL; Sundaram, G; Teo, C; Zinger, A | 1 |
Fukuwatari, T; Shibata, K | 1 |
Kaminski, T; Michalowska, M; Oksztulska-Kolanek, E; Pawlak, D; Znorko, B | 1 |
Brundin, L; Christensen, K; Coccaro, EF; Coussons-Read, M; Erhardt, S; Fanning, JR; Fuchs, D; Goiny, M; Lee, R | 1 |
Kanchanatawan, B; Maes, M | 1 |
Becquemont, L; Boniface, B; Boursier-Neyret, C; Chanson, P; Colle, R; Corruble, E; David, DJ; Falissard, B; Fève, B; Masson, P; Verstuyft, C; Walther, B; Werner, E | 1 |
Allers, KA; Harkin, A; McLoughlin, DM; Ryan, KM | 1 |
Al Saedi, A; Duque, G; Nurgali, K; Sharma, S; Summers, MA | 1 |
Bollag, WB; Ding, K; Elsalanty, M; Fulzele, S; Hamrick, MW; Hill, W; Irsik, DL; Isales, CM; Kaiser, H; Kennedy, EJ; McGee-Lawrence, ME; Pierce, JL; Sharma, AK; Shi, XM; Xu, J; Zhong, Q | 1 |
Cseh, EK; Janáky, T; Kecskeméti, G; Kormány, R; Rajda, C; Szabó, E; Szabó, Z; Tömösi, F; Vécsei, L | 1 |
Al Saedi, A; Duque, G; Guillemin, GJ; Khalil, M; Li, W; Lim, CK; Myers, DE; Vidal, C | 1 |
Gökmen, V; Yılmaz, C | 1 |
Altunçekiç Yıldırım, A; Ceran Serdar, C; Cihan, M; Doğan, Ö; Kurt, C; Serdar, MA | 1 |
4 review(s) available for tryptophan and picolinic acid
Article | Year |
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Ribosomal RNA metabolism in macrophages.
Topics: Adenine Nucleotides; Animals; Cytotoxicity, Immunologic; Humans; Immunity, Cellular; Macrophage Activation; Macrophages; Oligoribonucleotides; Picolinic Acids; RNA, Double-Stranded; RNA, Ribosomal; Signal Transduction; Tryptophan | 1992 |
Macrophage activating properties of the tryptophan catabolite picolinic acid.
Topics: Animals; Chemokine CCL3; Chemokine CCL4; Chemokines; Humans; Interferon-gamma; Macrophage Activation; Macrophage Inflammatory Proteins; Macrophages; Mice; Picolinic Acids; Recombinant Proteins; Tryptophan | 2003 |
New insights into tryptophan and its metabolites in the regulation of bone metabolism.
Topics: Animals; Bone and Bones; Humans; Kynurenine; Melatonin; ortho-Aminobenzoates; Picolinic Acids; Quinolinic Acid; Serotonin; Tryptophan; Xanthurenates | 2015 |
The multiple faces of tryptophan in bone biology.
Topics: Aged; Aged, 80 and over; Bone and Bones; Humans; Hydrolases; Osteoblasts; Osteoporosis; Picolinic Acids; Tryptophan | 2020 |
1 trial(s) available for tryptophan and picolinic acid
Article | Year |
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Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria.
Topics: Adult; Child; Child, Preschool; Disease Progression; Humans; Kynurenine; Malaria, Cerebral; Malawi; Picolinic Acids; Quinolinic Acid; Retrospective Studies; Tryptophan; Vietnam | 2003 |
37 other study(ies) available for tryptophan and picolinic acid
Article | Year |
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Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A.
Topics: Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Kinetics; Microbial Sensitivity Tests; Molecular Structure; Streptococcus pyogenes; Structure-Activity Relationship | 2019 |
Picolinic acid, a catabolite of tryptophan, as the second signal in the activation of IFN-gamma-primed macrophages.
Topics: Animals; Blotting, Northern; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Picolinic Acids; RNA; RNA Processing, Post-Transcriptional; RNA, Ribosomal; Signal Transduction; Tryptophan | 1990 |
Neurotoxicity of tryptophan metabolites.
Topics: Animals; Cerebral Cortex; Choline O-Acetyltransferase; Kynurenic Acid; Male; NADP; Nervous System Diseases; Neurons; Picolinic Acids; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1990 |
Quinolinate-induced cortical cholinergic damage: modulation by tryptophan metabolites.
Topics: 3-Hydroxyanthranilic Acid; Acetylcholine; Animals; Brain; Cerebral Cortex; In Vitro Techniques; Kynurenic Acid; Male; Neurotoxins; Parietal Lobe; Picolinic Acids; Potassium; Quinolines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1990 |
Oxidative reactivity of the tryptophan metabolites 3-hydroxyanthranilate, cinnabarinate, quinolinate and picolinate.
Topics: 3-Hydroxyanthranilic Acid; Catalase; Hydrogen-Ion Concentration; Kinetics; ortho-Aminobenzoates; Oxazines; Oxidation-Reduction; Oxygen Consumption; Picolinic Acids; Pyridines; Quinolinic Acid; Quinolinic Acids; Superoxide Dismutase; Tryptophan | 1987 |
Effect of tryptophan metabolites on the activities of rat liver pyridoxal kinase and pyridoxamine 5-phosphate oxidase in vitro.
Topics: Animals; Kinetics; Kynurenic Acid; Liver; Male; Oxidoreductases Acting on CH-NH Group Donors; Phosphotransferases; Picolinic Acids; Pyridoxal Kinase; Pyridoxaminephosphate Oxidase; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptamines; Tryptophan; Xanthurenates | 1985 |
Tryptophan deficiency and picolinic acid: effect on zinc metabolism and clinical manifestations of pellagra.
Topics: Animals; Body Weight; Bone and Bones; Diet; Male; Pellagra; Picolinic Acids; Rats; Rats, Inbred Strains; Tissue Distribution; Tryptophan; Zinc | 1987 |
Effects of dietary picolinate on mice deprived of tryptophan, niacin and vitamin B-6.
Topics: Animals; Blastocyst; Body Weight; Diet; Female; Mice; Niacin; Picolinic Acids; Pregnancy; Tryptophan; Vitamin B 6 Deficiency | 1983 |
Pentafluorobenzylation method for quantification of acidic tryptophan metabolites using electron capture negative ion mass spectrometry.
Topics: Fluorobenzenes; Kynurenic Acid; Kynurenine; Mass Spectrometry; Molecular Structure; ortho-Aminobenzoates; Picolinic Acids; Quaternary Ammonium Compounds; Quinolinic Acid; Tryptophan; Xanthurenates | 1995 |
Picolinic acid, a catabolite of L-tryptophan, is a costimulus for the induction of reactive nitrogen intermediate production in murine macrophages.
Topics: Animals; Arginine; Cell Line; Drug Synergism; Interferon-gamma; Interleukin-4; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Nitrites; omega-N-Methylarginine; Picolinic Acids; RNA, Messenger; Tryptophan; Tumor Necrosis Factor-alpha | 1993 |
The analgesic effects of tryptophan and its metabolites in the rat.
Topics: Analgesics; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hypolipidemic Agents; Iron Chelating Agents; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Pain; Picolinic Acids; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Tryptophan; Xanthurenates | 1998 |
The tryptophan catabolite picolinic acid selectively induces the chemokines macrophage inflammatory protein-1 alpha and -1 beta in macrophages.
Topics: Adjuvants, Immunologic; Animals; Cell Line; Chemokine CCL4; Gene Expression Regulation; Iron Chelating Agents; Macrophage Inflammatory Proteins; Macrophages; Mice; Mice, Inbred C57BL; Picolinic Acids; RNA, Messenger; Trans-Activators; Tryptophan | 2000 |
Changes in membrane fluidity induced by tryptophan and its metabolites.
Topics: Animals; Cell Cycle; Cell Membrane; Cholesterol; Fatty Acids; Hydroxyindoleacetic Acid; Kinetics; Kynurenic Acid; Kynurenine; Liver; Male; Membrane Fluidity; Membrane Lipids; Phospholipids; Picolinic Acids; Rats; Rats, Wistar; Tryptophan; Xanthurenates | 1999 |
Enzyme activities involved in tryptophan metabolism along the kynurenine pathway in rabbits.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; Animals; Carboxy-Lyases; Dioxygenases; Hydrolases; Indoleamine-Pyrrole 2,3,-Dioxygenase; Intestines; Kidney; Kynurenine; Kynurenine 3-Monooxygenase; Liver; Male; Mixed Function Oxygenases; Models, Chemical; Niacin; Oxygenases; Picolinic Acids; Rabbits; Tryptophan; Tryptophan Oxygenase | 2001 |
Effects of treatment with chromium picolinate on peripheral amino acid availability and brain monoamine function in the rat.
Topics: Animals; Brain; Catecholamines; Chromatography, High Pressure Liquid; Colorimetry; Corticosterone; Dose-Response Relationship, Drug; Male; Melatonin; Norepinephrine; Picolinic Acids; Pineal Gland; Rats; Rats, Sprague-Dawley; Tryptophan | 2003 |
A mobile tryptophan is the intrinsic charge transfer donor in a flavoenzyme essential for nikkomycin antibiotic biosynthesis.
Topics: Adenosine Diphosphate; Aminoglycosides; Binding Sites; Crystallization; Flavin-Adenine Dinucleotide; Flavoproteins; Mutation; Picolinic Acids; Tryptophan | 2007 |
Anti-infectious activity of tryptophan metabolites in the L-tryptophan-L-kynurenine pathway.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inhibitory Concentration 50; Iron Chelating Agents; Kynurenine; Methicillin-Resistant Staphylococcus aureus; Picolinic Acids; Time Factors; Tryptophan | 2009 |
Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats.
Topics: Animals; Blood Glucose; Carboxy-Lyases; Diabetes Mellitus, Experimental; Hepatocytes; Kynurenine; Male; Niacinamide; Picolinic Acids; Quinolinic Acid; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tritium; Tryptophan; Water | 2009 |
The kynurenine pathway and inflammation in amyotrophic lateral sclerosis.
Topics: Adult; Amyotrophic Lateral Sclerosis; Brain; Female; HLA-DR Antigens; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Male; Middle Aged; Picolinic Acids; Quinolinic Acid; Signal Transduction; Spinal Cord; Tryptophan | 2010 |
Characterization of the kynurenine pathway in NSC-34 cell line: implications for amyotrophic lateral sclerosis.
Topics: Animals; Cell Line, Transformed; Dose-Response Relationship, Drug; Drug Interactions; Hydrolases; Interferon-gamma; Iron Chelating Agents; Kynurenine; L-Lactate Dehydrogenase; Mice; Microglia; Motor Neurons; Picolinic Acids; Signal Transduction; Time Factors; Tryptophan; Tryptophan Oxygenase | 2011 |
Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats.
Topics: Aging; Animals; Brain; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kidney; Kynurenine; Liver; Pentosyltransferases; Picolinic Acids; Quinolinic Acid; Rats; Rats, Wistar; Signal Transduction; Transaminases; Tryptophan; Tryptophan Oxygenase | 2011 |
Chromium picolinate modulates serotonergic properties and carbohydrate metabolism in a rat model of diabetes.
Topics: Animals; Body Weight; Brain; Carbohydrate Metabolism; Chromium; Diabetes Mellitus, Experimental; Diet, High-Fat; Dietary Supplements; Drug Evaluation, Preclinical; Hydrocortisone; Insulin; Male; Picolinic Acids; Rats; Serotonin; Serotonin Agents; Streptozocin; Tryptophan | 2012 |
M. tuberculosis induces potent activation of IDO-1, but this is not essential for the immunological control of infection.
Topics: Animals; Blotting, Western; DNA Primers; Female; Gene Expression Profiling; Humans; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kaplan-Meier Estimate; Lung; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Microarray Analysis; Mycobacterium tuberculosis; Picolinic Acids; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Tryptophan; Tuberculosis | 2012 |
Increased 3-hydroxykynurenine serum concentrations differentiate Alzheimer's disease patients from controls.
Topics: Aged; Alzheimer Disease; Biomarkers; Blood-Brain Barrier; Brain Chemistry; Chromatography, High Pressure Liquid; Cognition Disorders; Female; Gas Chromatography-Mass Spectrometry; Humans; Kynurenic Acid; Kynurenine; Male; Neuropsychological Tests; Picolinic Acids; Quinolinic Acid; Spectrophotometry, Ultraviolet; Tryptophan | 2013 |
Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: amelioration by COX-2 inhibition.
Topics: Animals; Brain; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dizocilpine Maleate; Female; Gestational Age; Hyperkinesis; Kynurenic Acid; Kynurenine; Male; Picolinic Acids; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Pyrazoles; Quinolinic Acid; Random Allocation; Rats; Rats, Wistar; Schizophrenia; Sexual Maturation; Sulfonamides; Tryptophan | 2014 |
Involvement of the kynurenine pathway in human glioma pathophysiology.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytes; Biosynthetic Pathways; Brain Neoplasms; Carboxy-Lyases; CD11b Antigen; Cells, Cultured; Chromatography, High Pressure Liquid; Disaccharides; Gene Expression; Glial Fibrillary Acidic Protein; Glioma; Glucuronates; Humans; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenic Acid; Kynurenine; Picolinic Acids; Quinolinic Acid; Reverse Transcriptase Polymerase Chain Reaction; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured | 2014 |
Large amounts of picolinic acid are lethal but small amounts increase the conversion of tryptophan-nicotinamide in rats.
Topics: Animals; Body Weight; Carboxy-Lyases; Dose-Response Relationship, Drug; Iron Chelating Agents; Kynurenic Acid; Liver; Male; Niacinamide; ortho-Aminobenzoates; Pentosyltransferases; Picolinic Acids; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Xanthurenates | 2014 |
Tryptophan, kynurenine, and kynurenine metabolites: Relationship to lifetime aggression and inflammatory markers in human subjects.
Topics: Adult; Aggression; Biomarkers; C-Reactive Protein; Female; Humans; Inflammation; Interleukin-6; Kynurenic Acid; Kynurenine; Male; Picolinic Acids; Quinolinic Acid; Tryptophan | 2016 |
The Effects of Tryptophan Catabolites on Negative Symptoms and Deficit Schizophrenia are Partly Mediated by Executive Impairments: Results of Partial Least Squares Path Modeling.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Cognition Disorders; Executive Function; Female; Humans; Immunoglobulin A; Immunoglobulin M; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Male; Middle Aged; Neuropsychological Tests; Picolinic Acids; Psychiatric Status Rating Scales; Quinolinic Acid; Schizophrenia; Schizophrenic Psychology; Tryptophan; Xanthurenates; Young Adult | 2018 |
Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: A case-control study.
Topics: 3-Hydroxyanthranilic Acid; Adult; Case-Control Studies; Cohort Studies; Depressive Disorder, Major; Female; Humans; Kynurenine; Male; Middle Aged; Niacinamide; Picolinic Acids; Serotonin; Tryptophan; Xanthurenates | 2020 |
Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy.
Topics: 3-Hydroxyanthranilic Acid; Affect; Case-Control Studies; Electroconvulsive Therapy; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Picolinic Acids; Quinolinic Acid; Tryptophan; Xanthurenates | 2020 |
Picolinic acid, a tryptophan oxidation product, does not impact bone mineral density but increases marrow adiposity.
Topics: Adiposity; Animals; Bone Density; Bone Marrow; Mice; Mice, Inbred C57BL; Picolinic Acids; Tryptophan | 2020 |
A validated UHPLC-MS method for tryptophan metabolites: Application in the diagnosis of multiple sclerosis.
Topics: Adult; Biomarkers; Calibration; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Kynurenic Acid; Middle Aged; Multiple Sclerosis, Relapsing-Remitting; Picolinic Acids; Quinolinic Acid; Reference Standards; Tandem Mass Spectrometry; Tryptophan; Young Adult | 2020 |
Picolinic Acid, a Catabolite of Tryptophan, Has an Anabolic Effect on Bone In Vivo.
Topics: Anabolic Agents; Animals; Cell Differentiation; Mice; Mice, Inbred C57BL; Osteoblasts; Osteogenesis; Picolinic Acids; Tryptophan | 2020 |
Formation of amino acid derivatives in white and red wines during fermentation: Effects of non-Saccharomyces yeasts and Oenococcus oeni.
Topics: Amino Acids; Fermentation; Food Microbiology; Oenococcus; Picolinic Acids; Quinolinic Acid; Saccharomyces cerevisiae; Saccharomycetales; Torulaspora; Tryptophan; Wine | 2021 |
Kynurenine pathway in Coronavirus disease (COVID-19): Potential role in prognosis.
Topics: Adult; Aged; COVID-19; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Picolinic Acids; Prognosis; Quinolinic Acid; SARS-CoV-2; Tryptophan | 2022 |