tryptophan and phenytoin

tryptophan has been researched along with phenytoin in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199018 (75.00)18.7374
1990's0 (0.00)18.2507
2000's4 (16.67)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Chadwick, D; Gorrod, JW; Jenner, P; Marsden, CD; Reynolds, EH1
Bowmer, CJ; Lindup, WE1
Grahame-Smith, DG; Green, AR2
Cameron, JD; Chambers, RE1
Mabuchi, H; Nakahashi, H1
Botez, MI; Lalonde, R1
Oswald, I1
Jus, A; Jus, K; Villeneuve, A1
Donelli, MG; Garattini, S; Rosso, R1
Grimm, U; Schlenzka, K1
Gautier, J; Jus, A; Jus, K; Pineau, R; Pires, P; Villeneuv, R; Villeneuve, A1
Gamstorp, I; Meeuwisse, G; Tryding, N1
Elmazar, MM; Sullivan, FM1
Alphs, L; Davis, JM1
Jenner, P; Johnson, AL; Pratt, JA; Reynolds, EH; Shorvon, SD1
Depner, TA; Gulyassy, PF1
Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA1
DRUCKMAN, R; FRENCH, JH; GRUETER, BB; O'BRIEN, D1

Reviews

2 review(s) available for tryptophan and phenytoin

ArticleYear
Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine.
    Nature, 1976, Apr-08, Volume: 260, Issue:5551

    Topics: Animals; Brain; Clomipramine; Depression; Dopamine; Humans; Hydroxyindoleacetic Acid; Lithium; Models, Biological; Monoamine Oxidase Inhibitors; Motor Activity; Phenytoin; Rats; Serotonin; Synapses; Thyrotropin-Releasing Hormone; Tryptophan

1976
Drugs and sleep.
    Pharmacological reviews, 1968, Volume: 20, Issue:4

    Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan

1968

Trials

1 trial(s) available for tryptophan and phenytoin

ArticleYear
Drugs and sleep.
    Pharmacological reviews, 1968, Volume: 20, Issue:4

    Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan

1968

Other Studies

22 other study(ies) available for tryptophan and phenytoin

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Functional changes in cerebral 5-hydroxytryptamine metabolism in the mouse induced by anticonvulsant drugs.
    British journal of pharmacology, 1978, Volume: 62, Issue:1

    Topics: Animals; Behavior, Animal; Benzodiazepinones; Brain; Clonazepam; Cytochrome P-450 Enzyme System; Diazepam; Hydroxyindoleacetic Acid; Liver; Male; Mice; Phenytoin; Serotonin; Sleep; Time Factors; Tryptophan

1978
Binding of phenytoin, L-tryptophan and O-methyl red to albumin. Unexpected effect of albumin concentration on the binding of phenytoin and L-tryptophan.
    Biochemical pharmacology, 1978, Mar-15, Volume: 27, Issue:6

    Topics: Azo Compounds; Coloring Agents; Dialysis; Humans; Kinetics; ortho-Aminobenzoates; Phenytoin; Protein Binding; Serum Albumin; Tryptophan

1978
N-Acetyltryptophan ethyl ester: a new internal standard for the gas chromatographic determination of plasma anticonvulsant levels.
    Annals of clinical biochemistry, 1977, Volume: 14, Issue:4

    Topics: Anticonvulsants; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Tryptophan

1977
The effect of diphenylhydantoin on brain 5-hydroxytryptamine metabolism and function.
    Neuropharmacology, 1975, Volume: 14, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Clomipramine; Dihydroxyphenylalanine; Drug Synergism; Male; Monoamine Oxidase Inhibitors; Motor Activity; Phenytoin; Rats; Serotonin; Tranylcypromine; Tryptamines; Tryptophan

1975
Isolation and characterization of an endogenous drug-binding inhibitor present in uremic serum.
    Nephron, 1986, Volume: 44, Issue:4

    Topics: Furans; Gas Chromatography-Mass Spectrometry; Humans; Ligands; Phenytoin; Propionates; Protein Binding; Tryptophan; Uremia

1986
Chronic phenytoin and the stereotyped motor response induced by 5-methoxy-N,N-dimethyltryptamine in rats.
    Brain research, 1985, Feb-11, Volume: 326, Issue:2

    Topics: Animals; Brain Chemistry; Electroshock; Humans; Male; Methoxydimethyltryptamines; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stereotyped Behavior; Tranylcypromine; Tryptophan

1985
Polygraphic profile of oral tardive dyskinesia and of rabbit syndrome: for quantitative and qualitative evaluation.
    Diseases of the nervous system, 1973, Volume: 34, Issue:1

    Topics: Attention; Basal Ganglia Diseases; Benztropine; Diazepam; Electroencephalography; Electromyography; Humans; Lip; Masticatory Muscles; Motor Skills; Movement Disorders; Phenytoin; Sleep; Sleep, REM; Tremor; Tryptophan; Wakefulness

1973
On the neurotoxic effects induced by alkylating agents.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:11

    Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan

1966
[Studies on tryptophan metabolism in pellagra with special reference to drug-induced pellagra following INH and anticonvulsants].
    Dermatologische Monatschrift, 1974, Volume: 160, Issue:10

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Female; Humans; Isoniazid; Male; Middle Aged; Nutrition Disorders; Pellagra; Phenytoin; Tryptophan

1974
Studies on the action of certain pharmacological agents on tardive dyskinesia and on the rabbit syndrome.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 9, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antiparkinson Agents; Benztropine; Diazepam; Female; Humans; Injections, Intravenous; Male; Middle Aged; Movement Disorders; Phenytoin; Tranquilizing Agents; Tryptophan

1974
Effect of phenytoin on the tryptophan load test.
    Acta paediatrica Scandinavica, 1968, Volume: 57, Issue:2

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Diagnosis, Differential; Epilepsy; Female; Humans; Infant; Intellectual Disability; Male; Nervous System Diseases; Phenytoin; Pyridoxine; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates

1968
Effect of prenatal phenytoin administration on brain tryptophan metabolism of rat offspring during the preweaning period.
    The Journal of pharmacy and pharmacology, 1980, Volume: 32, Issue:10

    Topics: Animals; Animals, Suckling; Brain; Female; Male; Phenytoin; Pregnancy; Rats; Time Factors; Tryptophan

1980
Noncatecholaminergic treatments of tardive dyskinesia.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Amantadine; Anti-Anxiety Agents; Benzodiazepines; Cyproheptadine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Double-Blind Method; Dyskinesia, Drug-Induced; Enkephalin, Methionine; gamma-Aminobutyric Acid; Humans; Lithium; Parasympathomimetics; Phenytoin; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Substance Withdrawal Syndrome; Tryptophan

1982
Anticonvulsant drugs alter plasma tryptophan concentrations in epileptic patients: implications for antiepileptic action and mental function.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:10

    Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsies, Partial; Female; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Tryptophan

1984
Plasma protein binding in uremia: extraction and characterization of an inhibitor.
    Kidney international, 1980, Volume: 18, Issue:1

    Topics: Animals; Anion Exchange Resins; Binding, Competitive; Blood Proteins; Cattle; Horses; Humans; Phenytoin; Protein Binding; Renal Dialysis; Serum Albumin; Sheep; Styrenes; Tryptophan; Uremia

1980
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
    The Journal of endocrinology, 2000, Volume: 167, Issue:3

    Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil

2000
PYRIDOXINE AND INFANTILE MYOCLONIC SEIZURES.
    Neurology, 1965, Volume: 15

    Topics: Amino Acids; Drug Therapy; Electroencephalography; Epilepsies, Myoclonic; Humans; Infant; Kynurenic Acid; Metabolism, Inborn Errors; Myoclonus; Phenytoin; Pyridoxine; Seizures; Spasms, Infantile; Tryptophan; Urine; Xanthurenates

1965