tryptophan and phenobarbital

tryptophan has been researched along with phenobarbital in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199027 (77.14)18.7374
1990's3 (8.57)18.2507
2000's3 (8.57)29.6817
2010's2 (5.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Badawy, AA; Evans, M4
Calderini, G; Carlsson, A; Nordström, CH1
Sidransky, H; Verney, E2
Paine, AJ1
Cameron, JD; Chambers, RE1
Jorgensen, AJ; Majumdar, AP1
Kaliman, PA; Manandhar, SP1
Correia, MA; Lunetta, JM1
Anzenbacher, P; Fidler, V; Hudecek, J; Vajda, S1
Donelli, MG; Garattini, S; Rosso, R1
Jansson, I; Orrenius, S; Ramstad, E; Wilson, BJ1
Schmidt, H; Tolckmitt, W1
Seifert, J1
Marchand, P; Witschi, HP1
Oshika, H1
Ambike, SH; Baxter, RM1
Milstein, JM; Swaiman, KF1
Ogunlana, EO; Ramstad, E; Tyler, VE1
Jenner, P; Johnson, AL; Pratt, JA; Reynolds, EH; Shorvon, SD1
Ishii, K; Kamataki, T; Kato, R; Yamazoe, Y1
Hirshkowitz, M; Karacan, I; Thornby, JI1
Badawy, AA; Evans, M; Punjani, NF2
Levy, G; Wilson, TC1
Morimoto, S1
Guo, YQ; Hu, Q; Zhao, J; Zhu, WH1
SCHENKER, S; WARREN, KS1
Heyward, S; Li, L; Li, Z; Mackowiak, B; Swaan, PW; Wang, H; Welch, MA1

Reviews

1 review(s) available for tryptophan and phenobarbital

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

34 other study(ies) available for tryptophan and phenobarbital

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The effects of acute and chronic nicotine hydrogen (+)-tartrate administration and subsequent withdrawal on rat liver tryptophan pyrrolase activity and their comparison with those of morphine, phenobarbitone and ethanol.
    The Biochemical journal, 1975, Volume: 148, Issue:3

    Topics: Animals; Cycloheximide; Dactinomycin; Ethanol; Humans; Hydrocortisone; Liver; Male; Morphine; NADP; Nicotinyl Alcohol; Phenobarbital; Premedication; Pyridines; Rats; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Oxygenase

1975
Influence of transient ischemia on monoamine metabolism in the rat brain during nitrous oxide and phenobarbitone anaesthesia.
    Brain research, 1978, Nov-24, Volume: 157, Issue:2

    Topics: 5-Hydroxytryptophan; Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Brain; Catecholamines; Cerebellum; Cerebrovascular Circulation; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Hydroxyindoleacetic Acid; Ischemic Attack, Transient; Limbic System; Male; Nitrous Oxide; Norepinephrine; Phenobarbital; Rats; Serotonin; Tryptophan; Tyrosine

1978
Further enhancement by tryptophan of hepatic protein synthesis stimulated by phenobarbital or cortisone acetate.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:2

    Topics: Animals; Cortisone; Drug Synergism; Female; In Vitro Techniques; Liver; Male; Phenobarbital; Polyribosomes; Protein Biosynthesis; Rats; Tryptophan

1978
Effect of amino acids and inducers on the activity of the microsomal mono-oxygenase system in rat liver cell culture.
    Chemico-biological interactions, 1976, Volume: 13, Issue:3-4

    Topics: Amino Acids; Benz(a)Anthracenes; Benzopyrene Hydroxylase; Cells, Cultured; Enzyme Induction; Epithelial Cells; Epithelium; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxygenases; Phenobarbital; Tryptophan

1976
Effect of tryptophan or phenobarbital administration on hepatic polyribosomes and protein synthesis in rats force-fed a complete or threonine-devoid diet.
    The Journal of nutrition, 1977, Volume: 107, Issue:5

    Topics: Animals; Diet; Female; Leucine; Liver; Phenobarbital; Polyribosomes; Protein Biosynthesis; Rats; Subcellular Fractions; Threonine; Tryptophan; Tryptophan Oxygenase

1977
N-Acetyltryptophan ethyl ester: a new internal standard for the gas chromatographic determination of plasma anticonvulsant levels.
    Annals of clinical biochemistry, 1977, Volume: 14, Issue:4

    Topics: Anticonvulsants; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Tryptophan

1977
Influence of tryptophan on the level of hepatic microsomal cytochrome P-450 in well-fed normal, adrenalectomized, and phenobarbital-treated rats.
    Biochimica et biophysica acta, 1976, Sep-24, Volume: 444, Issue:2

    Topics: Adrenalectomy; Aniline Hydroxylase; Animals; Cytochrome P-450 Enzyme System; Dactinomycin; Hydrocortisone; Male; Microsomes, Liver; Phenobarbital; Proteins; Rats; Tryptophan

1976
The effects of ethanol on tryptophan pyrrolase activity and their comparison with those of phenobarbitone and morphine.
    Advances in experimental medicine and biology, 1975, Volume: 59

    Topics: Animals; Cricetinae; Ethanol; Fatty Acids, Nonesterified; Guinea Pigs; Humans; Kynurenine; Liver; Male; Morphine; Phenobarbital; Rats; Species Specificity; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase

1975
The effect of tryptophan on the phenobarbital-mediated induction of cytochrome P-450 in rat liver. The role of tryptophan 2,3-dioxygenase.
    Biomedical science, 1991, Volume: 2, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme System; Drug Combinations; Drug Therapy, Combination; Enzyme Induction; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase

1991
Acute hepatic heme depletion: impaired gluconeogenesis in rats.
    Seminars in hematology, 1989, Volume: 26, Issue:2

    Topics: Animals; Brain; Dicarbethoxydihydrocollidine; Gluconeogenesis; Glutathione; Glycerol; Heme; Hydroxyindoleacetic Acid; Liver; Phenobarbital; Porphyrias; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1989
Nanosecond fluorometry of the single tryptophan in cytochrome P-450e (P450IIB2).
    Biochemical and biophysical research communications, 1989, Aug-15, Volume: 162, Issue:3

    Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme System; Enzyme Induction; Kinetics; Microsomes, Liver; Phenobarbital; Protein Conformation; Rats; Solvents; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan

1989
The effects of chronic phenobarbitone administration and subsequent withdrawal on the activity of rat liver tryptohan pyrrolase and their resemblance to those of ethanol.
    The Biochemical journal, 1973, Volume: 135, Issue:3

    Topics: Animals; Depression, Chemical; Ethanol; Humans; Hydrocortisone; Injections, Intraperitoneal; Kynurenine; Liver; NAD; NADP; Phenobarbital; Rats; Sodium Chloride; Sodium Salicylate; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Oxygenase

1973
On the neurotoxic effects induced by alkylating agents.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:11

    Topics: Alanine; Animals; Anti-Bacterial Agents; Antimetabolites; Azaserine; Behavior, Animal; Central Nervous System; Chlorambucil; Cyclophosphamide; Cysteine; Drug Antagonism; Glycine; Male; Mannitol; Mechlorethamine; Melphalan; Nitrogen Mustard Compounds; Phenobarbital; Phenytoin; Rats; Seizures; Spasm; Thiourea; Triethylenemelamine; Tryptophan

1966
Conversion of agroclavine by mammalian cytochrome P-450.
    Biochimica et biophysica acta, 1971, Nov-12, Volume: 252, Issue:2

    Topics: Adrenal Glands; Animals; Benzopyrenes; Biotransformation; Carbon Isotopes; Chromatography, Thin Layer; Cytochromes; Ergot Alkaloids; Guinea Pigs; Isotope Labeling; Male; Microsomes; Microsomes, Liver; NADP; Phenobarbital; Protein Binding; Rabbits; Rats; Species Specificity; Spectrophotometry; Tryptophan

1971
[Metabolic kinetics of L-tryptophan under the effect of phenobarbital in the child].
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 8, Issue:1

    Topics: Amino Acids; Child; Child, Preschool; Enzyme Induction; Half-Life; Humans; Infant; Phenobarbital; Tryptophan; Tryptophan Oxygenase

1973
Tryptophan pyrrolase in rat liver after phenobarbital administration.
    Toxicology, 1973, Volume: 1, Issue:3

    Topics: Animals; Ascorbic Acid; Dactinomycin; Enzyme Activation; Enzyme Induction; Heme; Hydrocortisone; Liver; Male; Phenobarbital; Proteins; Rats; Time Factors; Tryptophan; Tryptophan Oxygenase

1973
The effects of chemical porphyrogens and drugs on the activity of rat liver tryptophan pyrrolase.
    The Biochemical journal, 1973, Volume: 136, Issue:4

    Topics: Acetamides; Allylisopropylacetamide; Animals; Apoproteins; Cytochrome P-450 Enzyme System; Dicarboxylic Acids; Griseofulvin; Heme; Humans; Hydrocortisone; Levulinic Acids; Liver; Male; Mental Disorders; Microsomes; Phenobarbital; Phenylbutazone; Porphyrias; Proadifen; Protein Precursors; Pyridines; Rats; Starvation; Time Factors; Tryptophan; Tryptophan Oxygenase

1973
Interference of Beryllium with enzyme induction in rat liver.
    Toxicology and applied pharmacology, 1971, Volume: 20, Issue:4

    Topics: Acetanilides; Aminopyrine; Animals; Beryllium; DNA; DNA Replication; Enzyme Induction; Hydrocortisone; Lethal Dose 50; Liver; Liver Regeneration; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Tryptophan; Tryptophan Oxygenase

1971
[Studies on 5-hydroxytryptophan decarboxylase activity in immature animals].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1966, Jul-20, Volume: 62, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Carboxy-Lyases; Dihydroxyphenylalanine; Guinea Pigs; Hydrocortisone; Indoleacetic Acids; Intestines; Kidney; Liver; Phenobarbital; Rats; Serotonin; Tryptophan

1966
Cytochrome P-450 and alkaloid synthesis in Claviceps purpurea.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:8

    Topics: Alkaloids; Ascomycota; Binding Sites; Carbon Isotopes; Cytochromes; Phenobarbital; Tryptophan

1970
Pyridoxine dependency and penicillamine.
    Neurology, 1970, Volume: 20, Issue:1

    Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Kidney Function Tests; Penicillamine; Phenobarbital; Pyridoxine; Seizures; Tryptophan

1970
Effects of some substances on ergot alkaloid production.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:1

    Topics: Ascorbic Acid; Benz(a)Anthracenes; Benzopyrenes; Catalase; Culture Media; Ergot Alkaloids; Hydrocortisone; Oxygenases; Phenobarbital; Phenylalanine; Thyroxine; Tryptophan

1969
Anticonvulsant drugs alter plasma tryptophan concentrations in epileptic patients: implications for antiepileptic action and mental function.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:10

    Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsies, Partial; Female; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Tryptophan

1984
Metabolic activation of mutagenic tryptophan pyrolysis products by rat liver microsomes.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: Animals; Biotransformation; Cell Fractionation; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Activation; Hot Temperature; Male; Methylcholanthrene; Microsomes, Liver; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Rats; Tryptophan

1980
Sleep spindles: pharmacological effects in humans.
    Sleep, 1982, Volume: 5, Issue:1

    Topics: Atropine; Azepines; Caffeine; Cerebral Cortex; Computers; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials; Flurazepam; Haloperidol; Humans; N-Methylscopolamine; Phenobarbital; Scopolamine; Scopolamine Derivatives; Sleep Stages; Thalidomide; Tryptophan

1982
The role of liver tryptophan pyrrolase in the opposite effects of chronic administration and subsequent withdrawal of drugs of dependence on rat brain tryptophan metabolism.
    The Biochemical journal, 1981, Apr-15, Volume: 196, Issue:1

    Topics: Animals; Brain; Humans; Liver; Male; Methylphenazonium Methosulfate; Morphine; Naloxone; Nicotine; Phenobarbital; Rats; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase

1981
Reversal by naloxone of the effects of chronic administration of drugs of dependence on rat liver and brain tryptophan metabolism.
    British journal of pharmacology, 1981, Volume: 74, Issue:2

    Topics: Animals; Brain; Corticosterone; Ethanol; Humans; Liver; Naloxone; Nicotine; Phenobarbital; Rats; Serotonin; Substance-Related Disorders; Tryptophan

1981
Kinetics of drug action in disease states. XLIII: Potentiating effect of L-tryptophan on the hypnotic action of phenobarbital and ethanol in rats.
    Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:10

    Topics: Animals; Blood Proteins; Brain; Drug Synergism; Ethanol; Female; Hypnotics and Sedatives; Infusions, Intravenous; Phenobarbital; Rats; Rats, Inbred Lew; Reflex; Renal Insufficiency; Tryptophan; Uremia

1994
Alteration of intercellular communication in a human urothelial carcinoma cell-line by tumor-promoting agents.
    International journal of urology : official journal of the Japanese Urological Association, 1996, Volume: 3, Issue:3

    Topics: Adult; Anticonvulsants; Antioxidants; Butylated Hydroxyanisole; Carcinogens; Carcinoma, Transitional Cell; Cell Communication; Clone Cells; Cyclamates; DDT; Dose-Response Relationship, Drug; Humans; Male; Phenobarbital; Saccharin; Tryptophan; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Urothelium

1996
Effects of stress factors, bioregulators, and synthetic precursors on indole alkaloid production in compact callus clusters cultures of Catharanthus roseus.
    Applied microbiology and biotechnology, 2001, Volume: 55, Issue:6

    Topics: Acyclic Monoterpenes; Alkaloids; Biomass; Catharanthus; Cells, Cultured; Culture Media; Mannitol; Phenobarbital; Phenylalanine; Plant Stems; Potassium Chloride; Quaternary Ammonium Compounds; Secologanin Tryptamine Alkaloids; Succinic Acid; Terpenes; Tryptamines; Tryptophan; Vinca Alkaloids; Yohimbine

2001
DRUGS RELATED TO THE EXACERBATION OR AMELIORATION OF HEPATIC COMA AND THEIR EFFECTS ON AMMONIA TOXICITY.
    Clinical science, 1963, Volume: 25

    Topics: Acetazolamide; Ammonia; Ammonium Chloride; Arginine; Chlorothiazide; Cortisone; Formaldehyde; Glutamates; Hepatic Encephalopathy; Hydrogen-Ion Concentration; Iproniazid; Mice; Morphine; Paraldehyde; Pentobarbital; Phenobarbital; Research; Toxicology; Tryptophan

1963
Mechanistic Insights of Phenobarbital-Mediated Activation of Human but Not Mouse Pregnane X Receptor.
    Molecular pharmacology, 2019, Volume: 96, Issue:3

    Topics: Animals; Cells, Cultured; Constitutive Androstane Receptor; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Gene Knockout Techniques; Humans; Mice; Phenobarbital; Pregnane X Receptor; Protein Binding; Receptors, Cytoplasmic and Nuclear; Species Specificity; Surface Plasmon Resonance; Tryptophan

2019