tryptophan has been researched along with neopterin in 202 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (3.96) | 18.7374 |
| 1990's | 33 (16.34) | 18.2507 |
| 2000's | 63 (31.19) | 29.6817 |
| 2010's | 84 (41.58) | 24.3611 |
| 2020's | 14 (6.93) | 2.80 |
| Authors | Studies |
|---|---|
| Howells, DW; Hyland, K; Smith, I; Strobel, S | 1 |
| Carreira, P; Heyes, MP; Silver, RM; Sutherland, SE | 1 |
| Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H; Weiss, G; Werner, ER; Werner-Felmayer, G | 1 |
| Borden, EC; Byrne, GI; Carlin, JM; Cornwell, R; Irizarry, A; Meyer, KC; Powers, C | 1 |
| Wachter, H; Weiss, G; Werner, ER; Werner-Felmayer, G | 1 |
| Fuchs, D; Hausen, A; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G | 5 |
| Dierich, MP; Fuchs, D; Möller, AA; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G | 1 |
| Borden, EC; Brown, RR; Grossberg, S; Horisberger, M; Nelson, B; Schiller, JH; Storer, B; Witt, PL | 1 |
| Forsman, A; Fuchs, D; Hagberg, L; Larsson, M; Norkrans, G; Reibnegger, G; Wachter, H; Werner, ER | 1 |
| Fuchs, D; Möller, AA; Reibnegger, G; Stöckle, E; Wachter, H; Werner, ER | 1 |
| Borden, EC; Brown, RR; Datta, SP; Goldstein, D; Sielaff, KM; Smalley, RV; Storer, BE; Teitelbaum, AP; Witt, PL | 1 |
| Brown, RR; Hank, JA; Kohler, PC; Lee, CM; Sondel, PM; Storer, BE | 1 |
| Fuchs, D; Hausen, A; Hirsch-Kauffmann, M; Reibnegger, G; Schweiger, M; Wachter, H; Werner, ER | 1 |
| Dierich, MP; Fuchs, D; Hausen, A; Jaeger, H; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G | 1 |
| Balemans, MG; de Morée, A; Ebels, I; Mans, DR; van Benthem, J | 1 |
| Balemans, MG; de Moreé, A; Ebels, I; Hendriks, HG; van Berlo, M | 1 |
| Fuchs, D; Gisslén, M; Hagberg, L; Larsson, M; Norkrans, G; Wachter, H | 2 |
| Bosmans, E; Cosyns, P; D'Hondt, P; Maes, M; Meltzer, HY; Okayli, G; Scharpé, S; Vanden Bossche, BV | 1 |
| Hizuta, A; Iwagaki, H; Orita, K; Tanaka, N | 1 |
| Fuchs, D; Gasse, T; Meyersbach, P; Murr, C; Schmutzhard, E; Wachter, H | 1 |
| Demisch, L; Engelhardt, W; Fischer, PA; Ott, M | 1 |
| Betts, T; Corbett, JA; Dursun, SM; Farrar, G; Handley, SL; Rickards, H | 1 |
| Heyes, MP; Major, EO; Markey, SP; Milstien, S; Saito, K; Vickers, JH | 1 |
| Denz, H; Fuchs, D; Herrmann, R; Huber, P; Orth, B; Wachter, H; Weiss, G | 1 |
| Abraham, NG; Bock, G; Fuchs, D; Kappas, A; Levere, RD; Lutton, JD; Wachter, H; Weiss, G; Werner-Felmayer, G | 1 |
| Baier-Bitterlich, G; Dapunt, O; Fuchs, D; Schröcksnadel, H; Wachter, H | 2 |
| Cranston, B; Fuchs, D; Giusti, RM; Hanchard, B; Maloney, EM; Manns, A; Morgan, OS; Steinberg, SM; Wachter, H; Williams, E | 1 |
| Baier-Bitterlich, G; Berzinsh, J; Fuchs, D; Grivane, I; Rudzite, V; Wachter, H | 1 |
| Altindag, ZZ; Fuchs, D; Iacobelli, S; Marth, C; Natoli, C; Wachter, H; Werner-Felmayer, G; Zeimet, AG | 1 |
| Hizuta, A; Iwagaki, H; Saito, S; Takeuchi, Y; Tanaka, N; Uomoto, M | 1 |
| Fuchs, D; Jellinger, K; Laccone, F; Leblhuber, F; Tilz, GP; Walli, J; Widner, B | 1 |
| Fuchs, D; Haun, M; Ludescher, C; Murr, C; Weiss, G; Widner, B; Zoller, H | 1 |
| Demel, U; Fuchs, D; Leblhuber, F; Tilz, GP; Walli, J; Widner, B | 2 |
| Fuchs, D; Kind, S; Kowald, E; Schmuth, M; Sepp, N; Widner, B | 1 |
| Bratslavska, O; Fuchs, D; Groma, V; Martinsons, A; Rudzite, V; Widner, B | 1 |
| Crawley, J; Dobbie, M; Marsh, K; Surtees, R; Waruiru, C | 1 |
| Baier-Bitterlich, G; Fritsch, P; Fuchs, D; Kowald, E; Ortner, U; Sepp, N; Widner, B; Wirleitner, B | 1 |
| Fuchs, D; Maloney, EM; St Claire Morgan, O; Werner, ER; Widner, B | 1 |
| Fuchs, D; Ledochowski, M; Murr, C; Schubert, C; Sperner-Unterweger, B; Widner, B | 1 |
| Baier-Bitterlich, G; Fuchs, D; Weiss, G; Widner, B; Wirleitner, B | 1 |
| Dierich, MP; Fuchs, D; Gerlach, D; Murr, C; Widner, B | 1 |
| Bruijn, JA; Fekkes, D; Hoekstra, R; Mulder, PG; Pepplinkhuizen, L; van den Broek, WW | 1 |
| Amann, A; Antretter, H; Fuchs, D; Hoffmann, G; Mayr, V; Rieder, J; Strohmenger, HU; Widner, B | 1 |
| Fuchs, D; Leblhuber, F; Widner, B | 1 |
| Fuchs, D; Laich, A; Ledochowski, M; Sperner-Unterweger, B; Widner, B | 1 |
| Bergant, A; Fuchs, D; Neurauter, G; Schennach, H; Schröcksnadel, H; Schröcksnadel, K; Widner, B | 1 |
| Fuchs, D; Laich, A; Neurauter, G; Schennach, H; Weiss, G; Wirleitner, B | 1 |
| Fuchs, D; Leblhuber, F; Neurauter, G | 1 |
| Fuchs, D; Neurauter, G; Wirleitner, B | 1 |
| Fuchs, D; Schroecksnadel, K; Wirleitner, B | 1 |
| Fuchs, D; Herold, M; Kaser, S; Ledochowski, M; Mur, E; Neurauter, G; Schroecksnadel, K | 1 |
| Fekkes, D; Hoekstra, R; Pepplinkhuizen, L; van de Wetering, BJ; Verhoeven, WM | 1 |
| Capuron, L; Fuchs, D; Lawson, DH; Miller, AH; Musselman, DL; Nemeroff, CB; Neurauter, G | 1 |
| Fuchs, D; Neurauter, G; Schennach, H; Schroecksnadel, K; Ueberall, F; Wirleitner, B | 1 |
| Capuron, L; Frick, B; Fuchs, D; Lawson, DH; Miller, AH; Musselman, DL; Nemeroff, CB; Schröcksnadel, K | 1 |
| Fuchs, D; Nagl, M; Neurauter, G; Wirleitner, B | 1 |
| Bannink, M; Eggermont, AM; Fekkes, D; Kruit, WH; Mulder, PG; Stoter, G; Van Gool, AR; van Ojik, HH | 1 |
| Bergant, A; Fuchs, D; Neurauter, G; Schröcksnadel, H; Schröcksnadel, K; Widner, B | 1 |
| Darlington, LG; Forrest, CM; Kennedy, A; Stone, TW; Stoy, N | 1 |
| Erglis, A; Fuchs, D; Jegere, S; Jurika, E; Kalnins, U; Rudzite, V; Silava, A; Trusinskis, K | 1 |
| Fuchs, D; Neurauter, G; Quirchmair, G; Sarcletti, M; Widner, B; Zangerle, R | 1 |
| Fuchs, D; Laganovska, G; Martinsons, A; Pitrans, B; Widner, B | 1 |
| Frick, B; Fuchs, D; Leblhuber, F; Neurauter, G; Schroecksnadel, K | 1 |
| Fuchs, D; Schennach, H; Schroecksnadel, K; Winkler, C; Wirleitner, B | 4 |
| Christofides, J; Darlington, LG; Egerton, M; Forrest, CM; Mackay, GM; Stone, TW; Stoy, N | 2 |
| Fuchs, D; Fuith, LC; Schroecksnadel, K; Winkler, C | 1 |
| Fuchs, D; Huber, R; Kemmler, G; Kohl, C; Neurauter, G; Schröcksnadel, H; Sölder, E; Sperner-Unterweger, B; Walch, T | 1 |
| Duftner, C; Fuchs, D; Schirmer, M; Schroecksnadel, K; Winkler, C; Wirleitner, B | 1 |
| Bridel, M; Christofides, J; Darlington, LG; Egerton, M; Forrest, CM; Mackay, GM; Stone, TW; Stoy, N | 1 |
| Aigner, F; Brandacher, G; Fuchs, D; Margreiter, R; Schroecksnadel, K; Schwelberger, H; Weiss, HG; Winkler, C | 1 |
| Frick, B; Fuchs, D; Schroecksnadel, K; Winkler, C | 1 |
| Frick, B; Fuchs, D; Schennach, H; Schroecksnadel, K; Winkler, C | 1 |
| Brandacher, G; Fuchs, D; Margreiter, R; Schroecksnadel, K; Winkler, C | 1 |
| Darlington, LG; Forrest, CM; Mackay, GM; Oxford, L; Stone, TW; Stoy, N | 1 |
| Fuchs, D; Schennach, H; Schroecksnadel, K; Winkler, C | 1 |
| Fuchs, D; Meerbergen, E; Moheno, P; Schennach, H; Schroecksnadel, K; Winkler, C | 1 |
| Bonatti, H; Bösmüller, C; Brandacher, G; Cakar, F; Fuchs, D; Margreiter, R; Obrist, P; Schneeberger, S; Werner, ER; Werner-Felmayer, G; Winkler, C | 1 |
| Fuchs, D; Murr, C; Richardsen, L; Weinlich, G; Winkler, C | 1 |
| Denz, HA; Fiegl, M; Fuchs, D; Prassl, K; Schroecksnadel, K; Winkler, C | 1 |
| Bellmann-Weiler, R; Fuchs, D; Garimorth, K; Schroecksnadel, K; Weiss, G; Zangerle, R | 1 |
| Artner-Dworzak, E; Denz, HA; Fiegl, M; Fuchs, D; Murr, C; Schroecksnadel, K; Talasz, H | 1 |
| Anderson, GM; Hoekstra, PJ; Kallenberg, CG; Minderaa, RB; Troost, PW | 1 |
| Darlington, LG; Forrest, CM; George, C; Mackay, GM; Stone, TW; Stoy, N | 1 |
| Bellmann-Weiler, R; Fuchs, D; Holzer, C; Larcher, C; Schroecksnadel, K; Weiss, G | 1 |
| Fuchs, D; Kemmler, G; Mumelter, B; Sarcletti, M; Schroecksnadel, K; Weiss, G; Winkler, C; Zangerle, R | 1 |
| Fuchs, D; Grander, G; Kofler, H; Kositz, C; Schennach, H; Schroecksnadel, K | 1 |
| Boasso, A; Cano, OD; Fuchs, D; Neurauter, G; Shearer, GM | 1 |
| Carrico, AW; Fuchs, D; Hecht, FM; Johnson, MO; Morin, SF; Remien, RH; Riley, ED | 1 |
| Cassidy, EM; Clarke, G; Cryan, JF; Dinan, TG; Fitzgerald, P; Quigley, EM | 1 |
| Fuchs, D; Jenny, M; Pirich, E; Santer, E; Schennach, H | 1 |
| Baydar, T; Bolukbasi, DN; Fuchs, D; Girgin, G; Ledochowski, M; Sahin, G; Salih, B; Schennach, H; Sorkun, K | 1 |
| Fuchs, D; Jenny, M; Klein, A; Ledochowski, M; Santer, E; Schennach, H; Ueberall, F | 1 |
| Hustad, S; Midttun, Ø; Ueland, PM | 1 |
| Brandacher, G; Fuchs, D; Margreiter, R; Schroecksnadel, K; Sucher, R; Weiss, G | 1 |
| Engin, AB; Fuchs, D; Ozkan, Y; Yardim-Akaydin, S | 1 |
| Fuchs, D; Gluhcheva, Y; Konwalinka, G; Kurz, K; Zvetkova, E | 1 |
| Bechter, K; Fuchs, D; Herzog, S; Maxeiner, HG; Reiber, H; Tumani, H | 1 |
| Chavele, KM; Fuchs, D; Keteepe-Arachi, T; Pusey, CD; Salama, AD; Seidel, JA; Shukla, D | 1 |
| Fuchs, D; Hidayat, BJ; Jenny, M; Pedersen, NR; Schennach, H | 1 |
| Ciprandi, G; De Amici, M; Fuchs, D; Tosca, M | 1 |
| Fuchs, D; Jenny, M; Klein, A; Kurz, K; Ledochowski, M; Schroecksnadel, S; Uberall, F | 1 |
| Fuchs, D; Jenny, M; Klieber, M; Kurz, K; Ledochowski, M; Schennach, H; Schroecksnadel, S; Zaknun, D | 1 |
| Fuchs, D; Klieber, M; Kurz, K; Meraner, V; Neurauter, G; Sperner-Unterweger, B; Zeimet, A | 1 |
| Brandacher, G; Fuchs, D; Koenig, P; Nagl, C; Neurauter, G; Schennach, H | 1 |
| Fuchs, D; Greilberger, J; Greilberger, M; Leblhuber, F; Tafeit, E; Wintersteiger, R | 1 |
| Baydar, T; Fuchs, D; Girgin, G; Kurukahvecioglu, O; Sahin, TT; Sare, M; Yuksel, O | 1 |
| Aubert, A; Barberger-Gateau, P; Capuron, L; Féart, C; Fuchs, D; Higueret, D; Layé, S; Schroecksnadel, S | 1 |
| Amato, M; Bellantonio, P; Bramanti, P; De Luca, G; Durastanti, V; Fantozzi, R; Locatelli, L; Lugaresi, A; Marino, S; Millefiorini, E; Picconi, O; Sessa, E; Solda', A; Totaro, R; Zipoli, V; Zorzon, M | 1 |
| Mete, G; Ozkan, Y; Sepici, V; Sepici-Dincel, A; Simsek, B | 1 |
| Fuchs, D; Galfalvy, HC; Grunebaum, MF; Lapidus, M; Mann, JJ; Oquendo, MA; Postolache, TT; Sublette, ME | 1 |
| Brandacher, G; Fuchs, D; Kurz, K; Schroecksnadel, S; Sucher, R | 1 |
| Kasparova, M; Krcmova, L; Melichar, B; Plisek, J; Sobotka, L; Solich, P; Solichova, D | 1 |
| Darlington, LG; Forrest, CM; Higgins, MJ; Mackay, GM; Millar, K; Oxford, L; Stone, TW | 1 |
| Christensen, MH; Lien, EA; Mellgren, G; Midttun, Ø; Nordbø, Y; Nygård, OK; Pedersen, EK; Ueland, PM; Varhaug, JE | 1 |
| Ciprandi, G; Fuchs, D | 1 |
| Fuchs, D; García-Lestón, J; Laffon, B; Mayan, O; Méndez, J; Moreira, AO; Pásaro, E; Roma-Torres, J; Schroecksnadel, S; Teixeira, JP | 1 |
| Fuchs, D; Grander, G; Kofler, H; Kurz, K | 1 |
| Aydin, A; Baydar, T; Charehsaz, M; Girgin, G; Palabiyik, SS; Sahin, G; Sarac, ES | 1 |
| Eussen, SJ; Midttun, Ø; Nygård, O; Pedersen, ER; Sulo, G; Tell, GS; Ueland, PM; Vollset, SE | 1 |
| Fuchs, D; Gostner, J; Jenny, M; Kurz, K; Schennach, H; Schroecksnadel, S; Weiss, G | 1 |
| Eussen, SJ; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE | 1 |
| Almer, G; Fuchs, D; Mangge, H; Meinitzer, A; Paulmichl, K; Prassl, R; Reininghaus, E; Schnedl, WJ; Summers, KL; Weghuber, D; Zelzer, S | 1 |
| Aguilera, F; Fuchs, D; García-Lestón, J; Laffon, B; Pásaro, E; Ríos-Vázquez, J; Valdiglesias, V | 1 |
| Fuchs, D; Gostner, JM; Kuehnl, S; Rollinger, JM; Schennach, H; Schroecksnadel, S; Schuster, D; Schwaiger, S; Stuppner, H; Temml, V | 1 |
| Becker, K; Fuchs, D; Gostner, J; Schennach, H; Schroecksnadel, S; Uberall, F; Zaknun, C | 1 |
| Baydar, T; Girgin, G; Palabiyik, SS; Tutkun, E; Yilmaz, OH | 1 |
| Hennings, A; Rief, W; Riemer, S; Schwarz, MJ; Selberdinger, VB; Stapf, TM | 1 |
| Aydin, A; Becker, K; Charehsaz, M; Fuchs, D; Gostner, JM; Kirmizibekmez, H; Schennach, H; Sipahi, H | 1 |
| Becker, K; Carriere, M; Fuchs, D; Geisler, S; Gostner, JM; Herlin, N; Schennach, H; Schroecksnadel, S | 1 |
| Apalset, EM; Eide, GE; Gjesdal, CG; Meyer, K; Midttun, Ø; Tell, GS; Ueland, PM; Ulvik, A | 1 |
| Capuron, L; Fuchs, D; Geisler, S; Kurz, K; Leblhuber, F; Sperner-Unterweger, B | 1 |
| Berger, K; Fuchs, D; Strasser, B | 1 |
| Kisa, U; Ozkan, Y; Simsek, B; Sukuroglu, MK; Tulmac, M | 1 |
| Eussen, SJ; Midttun, Ø; Nygård, O; Pedersen, ER; Ueland, PM; Ulvik, A | 1 |
| Eussen, SJ; Meyer, K; Midttun, Ø; Nygård, O; Tell, GS; Ueland, PM; Ulvik, A; Vollset, SE; Zuo, H | 1 |
| Eussen, SJ; Hustad, S; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE | 1 |
| Becker, K; Fuchs, D; Ganzera, M; Geisler, S; Gostner, JM; Schennach, H; Schroecksnadel, S; Überall, F | 1 |
| Fekkes, D; Hol, JW; Klimek, M; Stolker, RJ; Stronks, DL | 1 |
| Fuchs, D; Grammer, TB; Kleber, ME; März, W; Meinitzer, A; Murr, C | 1 |
| Fuchs, D; Gostner, JM; Jenny, M; Klein, A; Schennach, H; Schroecksnadel, S; Ueberall, F | 1 |
| Engin, A; Engin, AB; Karahalil, B; Karakaya, AE | 1 |
| Bipath, P; Levay, PF; Viljoen, M | 2 |
| Becker, K; Fuchs, D; Gostner, JM; Pease, JE; Raggl, E; Schennach, H; Überall, F | 1 |
| Dierkes, J; Drevon, CA; Gudbrandsen, OA; Karlsson, T; Midttun, Ø; Nygård, O; Pedersen, ER; Strand, E; Ueland, PM; Øyen, J | 1 |
| Cervinkova, B; Hansmanova, L; Krcmova, LK; Melichar, B; Sobotka, L; Solich, P; Solichova, D | 1 |
| de Bie, J; Grant, R; Guest, J; Guillemin, GJ | 1 |
| Eussen, SJ; Meyer, K; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE; Zuo, H | 1 |
| Dursun, A; Engin, A; Engin, AB; Gonul, II; Karamercan, A; Sepici Dincel, A | 1 |
| Burtscher, M; Fuchs, D; Gatterer, H; Geiger, D; Schauer, M; Strasser, B | 1 |
| Arpali-Tanas, E; Baydar, T; Girgin, G; Keles, S; Palabiyik, SS; Topdagi, E | 1 |
| Becker, K; Fuchs, D; Gostner, JM; Kofler, H; Strasser, B | 1 |
| Håberg, SE; Karlstad, Ø; London, SJ; Magnus, MC; Midtun, Ø; Nafstad, P; Nilsen, RM; Nystad, W; Parr, CL; Tunheim, G; Ueland, PM | 1 |
| Brody, LC; Deac, OM; Fan, R; Gardiner, CM; Lu, Z; McCann, A; Meyer, K; Midttun, Ø; Mills, JL; Molloy, AM; Quinn, L; Shane, B; Ueland, PM | 1 |
| Bezard, E; Camus, SM; Ceci, A; Fuertig, R; Hengerer, B; Luippold, AH | 1 |
| Fuchs, D; Gostner, JM; Gualdoni, GA; Zlabinger, GJ | 1 |
| Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA | 1 |
| Burtscher, M; Fuchs, D; Gatterer, H; Geiger, D; Gostner, JM; Schauer, M; Strasser, B | 1 |
| Culig, Z; Fritz, J; Fuchs, D; Heidegger, I; Klocker, H; Pichler, R; Steiner, E | 1 |
| Dušková, M; Humlová, Z; Klamová, H; Kujovská-Krčmová, L; Petráčková, M; Procházka, B; Vonka, V | 1 |
| Baydar, T; Girgin, G; Palabiyik, SS; Sipahi, H; Tutkun, E; Yilmaz, OH | 1 |
| Bengesser, SA; Birner, A; Dalkner, N; Fellendorf, FT; Fuchs, D; Holasek, SJ; Kapfhammer, HP; Mangge, H; Painold, A; Platzer, M; Queissner, R; Reininghaus, B; Reininghaus, EZ | 1 |
| Baydar, T; Cinici, E; Palabiyik, SS; Sipahi, H | 1 |
| Can, A; Fuchs, D; Groer, M; Krishnamurthy, VB; Millett, CE; Mukherjee, D; Postolache, TT; Reider, A; Saunders, EFH | 1 |
| D'Agata, A; Duffy, A; Fuchs, D; Groer, M; Louis-Jacques, A; Postolache, TT | 1 |
| Braicu, IE; Concin, N; Fuchs, D; Gostner, JM; Mahner, S; Obermayr, E; Sehouli, J; Vanderstichele, A; Vergote, I; Zeillinger, R | 1 |
| Becker, K; Fuchs, D; Gostner, JM; Pezzei, CK; Schennach, H; Schwaiger, S; Stuppner, H; Waltenberger, B | 1 |
| Fuchs, D; Geisler, S; Gostner, JM; Sperner-Unterweger, B | 1 |
| Aukrust, P; Gaardbo, JC; Gelpi, M; Gerstoft, J; Hoel, H; Holm, K; Hov, JR; Hove-Skovsgaard, M; Kummen, M; Nielsen, SD; Nwosu, F; Rudi, K; Seljeflot, I; Trøseid, M; Ueland, PM; Ullum, H; Valeur, J | 1 |
| Baydar, T; Girgin, G; Kılıçarslan, B; Şahin, TT; Taneri, F; Ünüvar, S; Yüksel, O | 1 |
| Bonassi, S; Fuchs, D; Gostner, JM; Lorenzi, M; Marcos-Pérez, D; Onder, G; Strasser, B; Valdiglesias, V | 1 |
| Aukrust, P; Dunlop, O; Dyrhol-Riise, AM; Kran, AB; Midttun, Ø; Mollnes, TE; Ormaasen, V; Quist-Paulsen, E; Stiksrud, B; Ueland, PM; Ueland, T | 1 |
| Baydar, T; Çatal, F; Erge, D; Girgin, G; Gözükara Bağ, HG; Kılıçarslan, B; Ünüvar, S | 1 |
| Aarsland, D; Giil, LM; McCann, A; Meyer, K; Midttun, Ø; Nordrehaug, JE; Nygård, O; Refsum, H; Smith, AD; Solvang, SH; Tell, GS; Ueland, PM; Vedeler, CA | 1 |
| Andreas, N; Chappell, KE; Grant, I; Holmes, E; Lewis, MR; Misra, R; Nicholson, JK; Nye, LC; Plumb, RS; Sarafian, MH; Swann, JR; Whiley, L; Wilson, ID | 1 |
| Albanes, D; Alcala, K; Arslan, AA; Blot, WJ; Brennan, P; Buring, JE; Cai, Q; Caporaso, NE; Fanidi, A; Freedman, ND; Gao, YT; Gaziano, JM; Giles, GG; Grankvist, K; Haiman, CA; Han, J; Hodge, AM; Huang, JY; Hveem, K; Johansson, M; Koh, WP; Lan, Q; Langhammer, A; Larose, TL; Le Marchand, L; Lee, IM; Li, HL; Luu, HN; Manjer, J; Midttun, Ø; Pettinger, M; Prentice, RL; Purdue, MP; Relton, C; Sesso, HD; Severi, G; Shu, XO; Stampfer, MJ; Stevens, VL; Thomson, CA; Ueland, PM; Ulvi, A; Visvanathan, K; Wang, R; Weinstein, SJ; Wilkens, LR; Wu, J; Xiang, YB; Yuan, JM; Zeleniuch-Jacquotte, A; Zhang, X; Zheng, W; Ziegler, RG | 1 |
| Ciprandi, G; Fuchs, D; Licari, A; Marseglia, G | 1 |
| Bellmann-Weiler, R; Fuchs, D; Kurz, K; Pizzini, A; Santifaller, J; Theurl, I; Tschurtschenthaler, C; Weiss, G | 1 |
| Gelpi, M; Lebech, AM; Lundgren, J; Midttun, Ø; Mocroft, A; Nielsen, SD; Trøseid, M; Ueland, PM; Ullum, H | 1 |
| Anh, DT; Fuchs, D; Geisler, S; Gostner, JM; Hoan, NX; Hung, HV; Lytton, SD; Nam, NM; Nghia, TH; Pallerla, SR; Quyet, D; Son, NT; Song, LH; Tien, TV; Toan, NL; Tuyen, HT; Van Tong, H; Velavan, TP | 1 |
| Babarczy, K; Galla, Z; Maróti, Z; Polyák, H; Pukoli, D; Rajda, C; Vécsei, L | 1 |
| Baydar, T; Efe, B; Girgin, G; Gürcü, S; Kılıçarslan, B; Yorulmaz, G | 1 |
| Andersson, LM; Fuchs, D; Gisslen, M; Gostner, JM; Nilsson, S; Robertson, J | 1 |
| Bergquist, A; Dhillon, AK; Folseraas, T; Hov, JR; Karlsen, TH; Kummen, M; Midttun, Ø; Rupp, C; Trøseid, M; Ueland, PM; Vesterhus, M; Voitl, R | 1 |
| Akram, F; Brenner, LA; Constantine, N; Dagdag, A; Dutra, SVO; Ernst, RK; Fuchs, D; Groer, MW; Lowry, CA; Makkar, H; Mohyuddin, I; Postolache, TT; Reynolds, MA; Spector, AM; Upadhyaya, SK; Wadhawan, A | 1 |
| Azuma, K; Hoshino, T; Imaizumi, A; Ishii, H; Karakawa, S; Kasajima, R; Kato, Y; Kawahara, A; Kikuchi, S; Matsuo, N; Miyagi, Y; Murotani, K; Sasada, T; Tagami, T; Tokito, T; Xiang, H | 1 |
| Arnhard, K; Fuchs, D; Geisler, S; Gleissenthall, GV; Kemmler, G; Mechtcheriakov, S; Oberacher, H; Schurr, T; Unterberger, C | 1 |
| Adkins, Y; Freytag, T; Jiang, X; Kable, ME; Newman, JW; Riazati, N; Stephensen, CB | 1 |
| Arslan, AA; Behndig, AF; Brennan, P; Cai, Q; Chen, C; Chen, Y; Fanidi, A; Freedman, ND; Gaziano, JM; Giles, GG; Huang, WY; Johansson, M; Koh, WP; Langhammer, A; Le Marchand, L; Manjer, J; Meyer, K; Midttun, Ø; Prentice, R; Robbins, HA; Sandsveden, M; Sesso, HD; Shu, XO; Stevens, VL; Sørgjerd, EP; Ueland, PM; Ulvik, A; Visvanathan, K; Wang, Y; Weinstein, SJ; Yuan, JM; Zahed, H; Zhang, X; Zheng, W | 1 |
| Andrews, PI; Antony, J; Ardern-Holmes, S; Bandodkar, S; Chung, J; Dale, RC; Farrar, MA; Gill, D; Guillemin, GJ; Guller, A; Gupta, S; Han, VX; Heng, B; Jones, HF; Kandula, T; Keating, BA; Kothur, K; Menezes, MP; Mohammad, S; Patel, S; Pillai, SC; Sampaio, H; Tantsis, E; Troedson, C; Webster, R; Yan, J | 1 |
| Gančarčíková, M; Javorská, L; Koblížek, V; Krčmová, LK; Matoušová, K; Melichar, B; Skála, M; Škop, J; Šmahel, P; Turoňová, D | 1 |
11 review(s) available for tryptophan and neopterin
| Article | Year |
|---|---|
Increased neopterin and interferon-gamma secretion and lower availability of L-tryptophan in major depression: further evidence for an immune response.
Topics: Adult; Age Factors; Antibodies, Monoclonal; Biopterins; Depressive Disorder; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunity, Cellular; Interferon-gamma; Male; Middle Aged; Neopterin; Regression Analysis; Sex Factors; Transfer RNA Aminoacylation; Tryptophan | 1994 |
Cellular immune activation, neopterin production, tryptophan degradation and the development of immunodeficiency.
Topics: Humans; Immune Tolerance; Immunologic Deficiency Syndromes; Interferon-gamma; Lymphocyte Activation; Neopterin; Respiratory Burst; Th1 Cells; Th2 Cells; Tryptophan | 2000 |
Neopterin production, tryptophan degradation, and mental depression--what is the link?
Topics: Depressive Disorder; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Neopterin; Serotonin; Tryptophan; Tryptophan Oxygenase | 2002 |
Crucial role of interferon-gamma and stimulated macrophages in cardiovascular disease.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Humans; Inflammation; Interferon-gamma; Macrophage Activation; Macrophages; Neopterin; Oxidative Stress; Reactive Oxygen Species; Tryptophan | 2006 |
Antitumoral activity of interferon-gamma involved in impaired immune function in cancer patients.
Topics: Anemia; Cachexia; Cell Proliferation; Depression; Humans; Immunologic Deficiency Syndromes; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Neoplasms; Neopterin; Tryptophan; Tumor Escape | 2006 |
Indoleamine-2, 3-dioxygenase and other interferon-gamma-mediated pathways in patients with human immunodeficiency virus infection.
Topics: HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Neopterin; Tryptophan | 2007 |
Neopterin, a prognostic marker in human malignancies.
Topics: Anemia; Biomarkers, Tumor; Cachexia; Cytokines; Depression; Fatigue; Humans; Neoplasms; Neopterin; Prognosis; Reactive Oxygen Species; Tryptophan; Weight Loss | 2010 |
Comparison of in vitro tests for antioxidant and immunomodulatory capacities of compounds.
Topics: Anti-Inflammatory Agents; Antioxidants; Humans; Immunologic Factors; Inflammation; Leukocytes, Mononuclear; Lipopolysaccharides; Mitogens; Models, Biological; Neopterin; Oxidative Stress; Plant Extracts; Reactive Oxygen Species; Tryptophan | 2014 |
Activated immune system and inflammation in healthy ageing: relevance for tryptophan and neopterin metabolism.
Topics: Aging; Animals; Health Status; Humans; Immunity, Cellular; Inflammation; Neopterin; Oxidative Stress; Reactive Oxygen Species; Tryptophan | 2014 |
Tryptophan Metabolism in Allergic Disorders.
Topics: Animals; Antioxidants; Biomarkers; Exercise; Food; Humans; Hypersensitivity; Immune System; Metabolic Networks and Pathways; Neopterin; Tryptophan | 2016 |
Immunometabolism in the Pathogenesis of Depressive Disorders - Therapeutic Considerations.
Topics: Antidepressive Agents; Depressive Disorder; Humans; Interferon-gamma; Neopterin; Phenylalanine; Tryptophan | 2018 |
8 trial(s) available for tryptophan and neopterin
| Article | Year |
|---|---|
Human biologic response modification by interferon in the absence of measurable serum concentrations: a comparative trial of subcutaneous and intravenous interferon-beta serine.
Topics: 2',5'-Oligoadenylate Synthetase; Adult; Aged; beta 2-Microglobulin; Biopterins; Drug Evaluation; Female; HLA Antigens; Humans; Injections, Intravenous; Injections, Subcutaneous; Interferon beta-1a; Interferon beta-1b; Interferon Type I; Interferon-beta; Interferons; Leukocytes, Mononuclear; Male; Middle Aged; Neoplasms; Neopterin; Random Allocation; Recombinant Proteins; Tryptophan | 1989 |
Effect of light therapy on biopterin, neopterin and tryptophan in patients with seasonal affective disorder.
Topics: Adult; Biopterins; Female; Humans; Immunity, Cellular; Male; Middle Aged; Neopterin; Personality Inventory; Phototherapy; Pteridines; Reference Values; Seasonal Affective Disorder; Seasons; Serotonin; Tryptophan | 2003 |
Interferon-alpha-induced changes in tryptophan metabolism. relationship to depression and paroxetine treatment.
Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Depression; Double-Blind Method; Female; Humans; Interferon-alpha; Kynurenine; Male; Melanoma; Middle Aged; Neopterin; Paroxetine; Selective Serotonin Reuptake Inhibitors; Time Factors; Tryptophan | 2003 |
Pegylated interferon-alpha2b treatment in melanoma patients: influence on amino acids, 5-hydroxyindolacetic acid and pteridine plasma concentrations.
Topics: Adult; Aged; Amino Acids; Biopterins; Drug Administration Schedule; Female; Humans; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Neopterin; Phenylalanine; Pilot Projects; Polyethylene Glycols; Pteridines; Randomized Controlled Trials as Topic; Recombinant Proteins; Time Factors; Tryptophan; Tyrosine | 2004 |
Neopterin production and tryptophan degradation during 24-months therapy with interferon beta-1a in multiple sclerosis patients.
Topics: Adult; Antibodies, Neutralizing; Biomarkers; Demography; Dose-Response Relationship, Drug; Female; Humans; Interferon beta-1a; Interferon-beta; Kynurenine; Male; Multiple Sclerosis; Neopterin; Time Factors; Tryptophan | 2011 |
Immunomodulation and oxidative stress in denim sandblasting workers: changes caused by silica exposure.
Topics: Adolescent; Adult; Child; Environmental Monitoring; Enzyme Induction; Humans; Immunity, Cellular; Immunomodulation; Kynurenine; Male; Middle Aged; Neopterin; Occupational Diseases; Occupational Exposure; Oxidative Stress; Silicon Dioxide; Silicosis; Superoxide Dismutase; Textile Industry; Tryptophan; Young Adult | 2013 |
Effects of a caloric restriction weight loss diet on tryptophan metabolism and inflammatory biomarkers in overweight adults.
Topics: Austria; Biomarkers; Body Mass Index; Caloric Restriction; Diet, Reducing; Female; Humans; Inflammation Mediators; Kynurenine; Leptin; Male; Middle Aged; Mood Disorders; Neopterin; Overweight; Phenylalanine; Risk; Tryptophan; Tyrosine; Weight Loss | 2015 |
Probiotic Supplements Beneficially Affect Tryptophan-Kynurenine Metabolism and Reduce the Incidence of Upper Respiratory Tract Infections in Trained Athletes: A Randomized, Double-Blinded, Placebo-Controlled Trial.
Topics: Adult; Athletes; Austria; Biomarkers; Double-Blind Method; Female; Gastrointestinal Microbiome; Health Status; Humans; Kynurenine; Male; Neopterin; Phenylalanine; Physical Conditioning, Human; Physical Endurance; Physical Fitness; Probiotics; Respiratory Tract Infections; Risk Factors; Seasons; Time Factors; Tryptophan; Tyrosine; Young Adult | 2016 |
183 other study(ies) available for tryptophan and neopterin
| Article | Year |
|---|---|
Tryptophan and serotonin metabolism in familial erythrophagocytic lymphohistiocytosis.
Topics: Aging; Amino Acids; Biopterins; Child, Preschool; Etoposide; Histiocytosis, Non-Langerhans-Cell; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Male; Methotrexate; Neopterin; Prednisolone; Serotonin; Tryptophan | 1992 |
Alterations in tryptophan metabolism in the toxic oil syndrome and in the eosinophilia-myalgia syndrome.
Topics: Arthritis, Rheumatoid; Biopterins; Brassica; Eosinophilia-Myalgia Syndrome; Fatty Acids, Monounsaturated; Humans; Kynurenine; Neopterin; Plant Oils; Quinolinic Acid; Quinolinic Acids; Rapeseed Oil; Reference Values; Scleroderma, Systemic; Syndrome; Tryptophan | 1992 |
Iron modulates interferon-gamma effects in the human myelomonocytic cell line THP-1.
Topics: Biopterins; Dioxygenases; Dose-Response Relationship, Drug; Enzyme Induction; GTP Cyclohydrolase; Histocompatibility Antigens Class II; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Iron; Leukemia, Myeloid; Neopterin; Oxygenases; Tryptophan; Tumor Cells, Cultured | 1992 |
Effects of interferons beta or gamma on neopterin biosynthesis and tryptophan degradation by human alveolar macrophages in vitro: synergy with lipopolysaccharide.
Topics: Adult; Biopterins; Chlamydophila psittaci; Drug Synergism; Enzyme Induction; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-beta; Interferon-gamma; Lipopolysaccharides; Macrophages, Alveolar; Neopterin; Psittacosis; Tryptophan; Tryptophan Oxygenase | 1992 |
Peak E contaminated L-tryptophan and immune activation.
Topics: Biopterins; Drug Contamination; Humans; Immunity, Cellular; Kynurenine; Leukocytes, Mononuclear; Neopterin; Tryptophan; Tryptophan Oxygenase | 1991 |
Induction of indoleamine 2,3-dioxygenase in human cells in vitro.
Topics: Biopterins; Cells, Cultured; Enzyme Induction; Fibroblasts; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferons; Leukocytes, Mononuclear; Lipopolysaccharides; Macrophages; Neoplasm Proteins; Neopterin; Stimulation, Chemical; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Relationships between pteridine synthesis and tryptophan degradation.
Topics: Biopterins; Cells, Cultured; Enzyme Induction; Humans; Hydrolases; Interferon-gamma; Macrophages; NAD; Neopterin; Pteridines; Tryptophan; Tryptophan Oxygenase | 1991 |
Increased endogenous interferon-gamma and neopterin correlate with increased degradation of tryptophan in human immunodeficiency virus type 1 infection.
Topics: Adult; Biopterins; Chromatography, High Pressure Liquid; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Interferon-gamma; Kynurenine; Male; Middle Aged; Neopterin; Radioimmunoassay; Tryptophan | 1991 |
Neopterin formation and tryptophan degradation by a human myelomonocytic cell line (THP-1) upon cytokine treatment.
Topics: Biopterins; Cell Line; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Interferon Type I; Interferon-gamma; Lipopolysaccharides; Macrophages; Monocytes; Neopterin; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase | 1990 |
Biological and clinical effects of the combination of beta- and gamma-interferons administered as a 5-day continuous infusion.
Topics: 2',5'-Oligoadenylate Synthetase; Aspartate Aminotransferases; beta 2-Microglobulin; Biomarkers; Biopterins; Blood Proteins; Drug Evaluation; Drug Therapy, Combination; Enzyme Induction; Female; Humans; Infusions, Intravenous; Interferon Type I; Interferon-gamma; Leukocyte Count; Male; Middle Aged; Monocytes; Neoplasms; Neopterin; Recombinant Proteins; Tryptophan | 1990 |
Immune activation and decreased tryptophan in patients with HIV-1 infection.
Topics: Adult; Biopterins; Enzyme Induction; HIV Infections; HIV-1; Humans; Interferon-gamma; Middle Aged; Neopterin; Tryptophan; Tryptophan Oxygenase | 1990 |
Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and with neurologic/psychiatric symptoms.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopterins; Dementia; Humans; Kynurenine; Male; Middle Aged; Neopterin; Peripheral Nervous System Diseases; Tryptophan | 1990 |
Tumour necrosis factor-alpha and lipopolysaccharide enhance interferon-induced tryptophan degradation and pteridine synthesis in human cells.
Topics: Biopterins; Drug Interactions; Enzyme Induction; Fibroblasts; Humans; Interferon Type I; Interferon-gamma; Interferons; Leukocytes, Mononuclear; Lipopolysaccharides; Macrophages; Neopterin; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase; Tumor Necrosis Factor-alpha | 1989 |
Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma.
Topics: Biopterins; Coenzymes; Enzyme Activation; Fibroblasts; GTP Cyclohydrolase; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Macrophages; Neopterin; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured | 1989 |
Altered tryptophan and neopterin metabolism in cancer patients treated with recombinant interleukin 2.
Topics: Biopterins; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Interleukin-2; Kynurenine; Neoplasms; Neopterin; Recombinant Proteins; Tryptophan | 1989 |
Interferon-gamma-induced degradation of tryptophan by human cells in vitro.
Topics: Biopterins; Cells, Cultured; Chromatography, High Pressure Liquid; Fibroblasts; HeLa Cells; Humans; Indicators and Reagents; Interferon-gamma; Kynurenine; Neopterin; ortho-Aminobenzoates; Tryptophan | 1987 |
Tryptophan degradation in patients infected by human immunodeficiency virus.
Topics: Acquired Immunodeficiency Syndrome; Adult; Biopterins; Humans; Kynurenine; Male; Neopterin; Reference Values; Retrospective Studies; Tryptophan | 1988 |
The effect of reduced neopterin on the synthesis of several methylated indoles in the pineal gland of adult male golden hamsters, kept under standardized conditions.
Topics: 5-Hydroxytryptophan; Animals; Biopterins; Cricetinae; Indoles; Male; Melatonin; Mesocricetus; Methylation; Neopterin; Pineal Gland; Pteridines; Tryptophan | 1985 |
The influence of some pteridines on pineal 5-methoxyindole synthesis in male Wistar rats periodically exposed to either white or green light.
Topics: 5-Methoxytryptamine; Animals; Biopterins; Hydroxyindoleacetic Acid; Indoles; Light; Male; Melanins; Neopterin; Pineal Gland; Pteridines; Pterins; Rats; Rats, Inbred Strains; Tryptophan | 1983 |
Tryptophan concentrations increase in cerebrospinal fluid and blood after zidovudine treatment in patients with HIV type 1 infection.
Topics: Adult; Aged; Biopterins; CD4 Lymphocyte Count; Female; HIV Infections; HIV-1; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Immunoglobulin G; Male; Methoxyhydroxyphenylglycol; Middle Aged; Neopterin; Serotonin; Tryptophan; Zidovudine | 1994 |
Decreased serum tryptophan in patients with cancer cachexia correlates with increased serum neopterin.
Topics: Adult; Aged; Aged, 80 and over; Biopterins; Cachexia; Carcinoembryonic Antigen; Female; Gastrointestinal Neoplasms; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Macrophages; Male; Middle Aged; Neoplasm Proteins; Neopterin; Tryptophan; Tryptophan Oxygenase | 1995 |
Neopterin production and tryptophan degradation in acute Lyme neuroborreliosis versus late Lyme encephalopathy.
Topics: Acute Disease; Adult; Aged; Biopterins; Borrelia Infections; Chromatography, High Pressure Liquid; Female; Humans; Kynurenine; Longitudinal Studies; Male; Middle Aged; Neopterin; Nervous System Diseases; Tryptophan | 1994 |
Interleukin-2, soluble interleukin-2-receptor, neopterin, L-tryptophan and beta 2-microglobulin levels in CSF and serum of patients with relapsing-remitting or chronic-progressive multiple sclerosis.
Topics: Acute Disease; Adult; beta 2-Microglobulin; Biomarkers; Biopterins; Blood Proteins; Cerebrospinal Fluid Proteins; Chronic Disease; Female; Humans; Interleukin-2; Male; Middle Aged; Multiple Sclerosis; Neopterin; Receptors, Interleukin-2; Recurrence; Sensitivity and Specificity; Tryptophan | 1993 |
Elevated plasma kynurenine in Tourette syndrome.
Topics: Adolescent; Adult; Biopterins; Child; Female; Humans; Kynurenine; Male; Neopterin; Reference Values; Tourette Syndrome; Tryptophan | 1994 |
A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Topics: 3-Hydroxyanthranilic Acid; Animals; Biopterins; Brain; Encephalitis; Fetus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Macaca mulatta; Myelitis; Neopterin; Poliomyelitis; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase | 1993 |
Weight loss in patients with hematological neoplasias is associated with immune system stimulation.
Topics: Biomarkers; Biopterins; Cachexia; Female; Follow-Up Studies; Humans; Immunity, Cellular; Interferon-gamma; Kynurenine; Lymphoma; Male; Multiple Myeloma; Neopterin; Tryptophan; Weight Loss | 1993 |
Comparative effects of heme and metalloporphyrins on interferon-gamma-mediated pathways in monocytic cells (THP-1).
Topics: Biopterins; Heme; HLA-DR Antigens; Humans; Interferon-gamma; Kinetics; Leukemia, Monocytic, Acute; Metalloporphyrins; Neopterin; Recombinant Proteins; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured | 1993 |
Decreased plasma tryptophan in pregnancy.
Topics: Biopterins; Female; Humans; Kynurenine; Neopterin; Postpartum Period; Pregnancy; Tryptophan | 1996 |
Differential patterns of serum biomarkers of immune activation in human T-cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis, and adult T-cell leukemia/lymphoma.
Topics: Adult; beta 2-Microglobulin; Biomarkers; Biopterins; Cross-Sectional Studies; Female; Forecasting; HTLV-I Antibodies; Humans; Jamaica; Kynurenine; Leukemia-Lymphoma, Adult T-Cell; Male; Middle Aged; Neopterin; Paraparesis, Tropical Spastic; Pilot Projects; Proportional Hazards Models; Seroepidemiologic Studies; Survival Rate; Tryptophan | 1996 |
Increase of tryptophan in serum and in cerebrospinal fluid of patients with HIV infection during zidovudine therapy.
Topics: Anti-HIV Agents; Biopterins; Chromatography, High Pressure Liquid; HIV Infections; HIV Seropositivity; Humans; Kynurenine; Neopterin; Quinolinic Acid; Radioimmunoassay; Time Factors; Tryptophan; Zidovudine | 1996 |
Activated cellular immunity and decreased serum tryptophan in healthy pregnancy.
Topics: Biopterins; Chromatography, High Pressure Liquid; Female; Gestational Age; Humans; Immunity, Cellular; Kynurenine; Neopterin; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Reference Values; Tryptophan | 1996 |
Serum tryptophan, kynurenine, and neopterin in patients with Guillain-Barre-syndrome (GBS) and multiple sclerosis (MS).
Topics: Biopterins; Humans; Kynurenine; Multiple Sclerosis; Neopterin; Polyradiculoneuropathy; Reference Values; Time Factors; Tryptophan | 1996 |
Tumor-associated antigen 90K activates myelomonocytic cell line THP-1.
Topics: Adjuvants, Immunologic; Antigens, Neoplasm; Biomarkers, Tumor; Biopterins; Carrier Proteins; Cell Line; Female; Glycoproteins; Humans; Interferon-gamma; Lipoproteins; Monocytes; Neoplasm Proteins; Neopterin; Tryptophan | 1996 |
Cancer cachexia and depressive states: a neuro-endocrine-immunological disease?
Topics: Adult; Aged; Aged, 80 and over; Biopterins; Cachexia; Depression; Female; Gastrointestinal Neoplasms; Humans; Hydrocortisone; Male; Middle Aged; Neopterin; Serotonin; Tryptophan | 1997 |
Activated immune system in patients with Huntington's disease.
Topics: Adult; Antigens, CD; Complement C3; Female; Humans; Huntington Disease; Immunoglobulins; Kynurenine; Male; Middle Aged; Neopterin; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Tryptophan | 1998 |
Modulation of neopterin formation and tryptophan degradation by Th1- and Th2-derived cytokines in human monocytic cells.
Topics: Cell Line; Cytokines; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-10; Interleukin-12; Interleukin-4; Monocytes; Neopterin; Recombinant Proteins; Th1 Cells; Th2 Cells; Tryptophan | 1999 |
Degradation of tryptophan in neurodegenerative disorders.
Topics: Alzheimer Disease; Biomarkers; Humans; Huntington Disease; Intellectual Disability; Interleukin-2; Kynurenine; Neopterin; Receptors, Interleukin-2; Receptors, Tumor Necrosis Factor; Tryptophan; Tumor Necrosis Factor-alpha | 1999 |
Degradation of tryptophan in patients with systemic lupus erythematosus.
Topics: Depression; Humans; Kynurenine; Lupus Erythematosus, Systemic; Neopterin; Reference Values; Tryptophan | 1999 |
Kynurenine and neopterin in chronic glomerulonephritis.
Topics: Biomarkers; Chronic Disease; Creatinine; Fasting; Glomerular Filtration Rate; Glomerulonephritis; Glomerulonephritis, Membranous; Humans; Immunity, Cellular; Kidney; Kidney Failure, Chronic; Kynurenine; Neopterin; Tryptophan | 1999 |
Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism?
Topics: Antimalarials; Biopterins; Brain; Child; Child, Preschool; Chromatography, High Pressure Liquid; Endothelium; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyindoleacetic Acid; Infant; Kenya; Malaria, Cerebral; Microglia; Neopterin; Nitrates; Nitrites; Quinolinic Acid; Tryptophan | 2000 |
Tryptophan degradation and immune activation in Alzheimer's disease.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Female; Humans; Interferon-gamma; Kynurenine; Male; Middle Aged; Neopterin; Tryptophan | 2000 |
Enhanced tryptophan degradation in systemic lupus erythematosus.
Topics: Adult; Aged; Female; Humans; Kynurenine; Lupus Erythematosus, Systemic; Male; Middle Aged; Neopterin; Tryptophan | 2000 |
Central nervous system activation of the indoleamine-2,3-dioxygenase pathway in human T cell lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis.
Topics: Adult; Aged; Brain; Enzyme Activation; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Middle Aged; Neopterin; Nitric Oxide; Paraparesis, Tropical Spastic; Tryptophan; Tryptophan Oxygenase | 2000 |
Immune reaction links disease progression in cancer patients with depression.
Topics: Depression; Disease Progression; Humans; Neoplasms; Neopterin; Serotonin; Tryptophan | 2000 |
Neopterin production and tryptophan degradation in humans infected by Streptococcus pyogenes.
Topics: Humans; Kynurenine; Neopterin; Streptococcal Infections; Streptococcus pyogenes; Tonsillitis; Tryptophan | 2001 |
Effect of electroconvulsive therapy on biopterin and large neutral amino acids in severe, medication-resistant depression.
Topics: Adult; Aged; Amino Acids, Neutral; Biopterins; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Neopterin; Phenylalanine; Psychiatric Status Rating Scales; Psychotic Disorders; Reference Values; Treatment Outcome; Tryptophan; Tyrosine; Valine | 2001 |
Monitoring of immune activation using biochemical changes in a porcine model of cardiac arrest.
Topics: Animals; Disease Models, Animal; Heart Arrest; Immune System; Kynurenine; Neopterin; Swine; Tryptophan; Tryptophan Oxygenase | 2001 |
Increased neopterin production and tryptophan degradation in advanced Parkinson's disease.
Topics: Aged; Chromatography, High Pressure Liquid; Female; Humans; Immunity, Cellular; Kynurenine; Male; Neopterin; Parkinson Disease; Tryptophan | 2002 |
Longitudinal study of tryptophan degradation during and after pregnancy.
Topics: Adult; Alanine Transaminase; Antigens, CD; Biomarkers; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Kynurenine; Longitudinal Studies; Neopterin; Postpartum Period; Pregnancy; Pregnancy Trimesters; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Tryptophan | 2003 |
Atorvastatin suppresses interferon-gamma -induced neopterin formation and tryptophan degradation in human peripheral blood mononuclear cells and in monocytic cell lines.
Topics: Atorvastatin; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Leukocytes, Mononuclear; Monocytes; Neopterin; Pyrroles; Tryptophan | 2003 |
Oxidative damage and cytogenic analysis in leukocytes of Parkinson's disease patients.
Topics: Cytogenetic Analysis; Homocysteine; Humans; Inflammation; Interferon-gamma; Leukocytes; Macrophages; Neopterin; Oxidative Stress; Parkinson Disease; T-Lymphocytes; Tryptophan | 2003 |
Death from pneumonia in patients with progressive dementia.
Topics: Cross Infection; Dementia; Humans; Neopterin; Pneumonia; Predictive Value of Tests; Tryptophan | 2003 |
Anemia and congestive heart failure.
Topics: Anemia; Causality; Cell Division; Chronic Disease; Comorbidity; Dioxygenases; Heart Failure; Hematopoiesis; Hemoglobins; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Neopterin; Oxygenases; Prevalence; Tryptophan | 2003 |
Increased degradation of tryptophan in blood of patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Biomarkers; Chromatography, High Pressure Liquid; Cohort Studies; Female; Humans; Kynurenine; Male; Neopterin; Probability; Prognosis; Sensitivity and Specificity; Severity of Illness Index; Tryptophan | 2003 |
PADMA 28 modulates interferon-gamma-induced tryptophan degradation and neopterin production in human PBMC in vitro.
Topics: Cells, Cultured; Concanavalin A; Ethanol; Humans; Interferon-gamma; Iron Chelating Agents; Kynurenine; Mitogens; Monocytes; Neopterin; Phytohemagglutinins; Plant Extracts; Solvents; Tryptophan | 2004 |
Plasma homocysteine and immune activation in patients with malignant melanoma undergoing treatment with IFN-alpha.
Topics: Adult; Aged; Antineoplastic Agents; Female; Folic Acid; Homocysteine; Humans; Interferon alpha-2; Interferon-alpha; Kynurenine; Macrophage Activation; Male; Melanoma; Middle Aged; Neopterin; Predictive Value of Tests; Recombinant Proteins; Tryptophan; Vitamin B 12 | 2004 |
Down-regulatory effect of N-chlorotaurine on tryptophan degradation and neopterin production in human PBMC.
Topics: Cell Survival; Concanavalin A; Down-Regulation; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Neopterin; Phytohemagglutinins; Taurine; Tryptophan; Tryptophan Oxygenase | 2004 |
Tryptophan degradation during and after gestation.
Topics: Adult; Alanine Transaminase; Antigens, CD; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Longitudinal Studies; Neopterin; Postpartum Period; Pregnancy; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Tryptophan; Tryptophan Oxygenase | 2003 |
Kynurenine and neopterin levels in patients with rheumatoid arthritis and osteoporosis during drug treatment.
Topics: Arthritis, Rheumatoid; Case-Control Studies; Etidronic Acid; Female; Humans; Kynurenine; Methotrexate; Neopterin; Osteoporosis; Prednisolone; Raloxifene Hydrochloride; Receptors, Glutamate; Tryptophan | 2003 |
Prognostic value of tryptophan load test followed by serum kynurenine determination. Its comparison with pyridoxal-5-phosphate, kynurenine, homocysteine and neopterin amounts.
Topics: Biomarkers; Case-Control Studies; Coronary Disease; Homocysteine; Humans; Kynurenine; Neopterin; Prognosis; Pyridoxal Phosphate; Tryptophan | 2003 |
Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Female; HIV Infections; HIV-1; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Male; Middle Aged; Neopterin; T-Lymphocytes; Tryptophan; Tryptophan Oxygenase | 2003 |
Kynurenine and neopterin in the aqueous humor of the anterior chamber of the eye and in serum of cataract patients.
Topics: Aged; Aged, 80 and over; Aqueous Humor; Cataract; Exfoliation Syndrome; Humans; Kynurenine; Neopterin; Oxidative Stress; Selenium; Tryptophan | 2003 |
Increasing production of homocysteine and neopterin and degradation of tryptophan with older age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Dioxygenases; Enzyme-Linked Immunosorbent Assay; Female; Folic Acid; Homocysteine; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Macrophages; Male; Middle Aged; Neopterin; T-Lymphocytes; Time Factors; Tryptophan; Vitamin B 12 | 2004 |
St. John's wort (Hypericum perforatum) counteracts cytokine-induced tryptophan catabolism in vitro.
Topics: Cell Survival; Chromatography, High Pressure Liquid; Concanavalin A; Cytokines; Humans; Hypericum; In Vitro Techniques; Indicators and Reagents; Interferon-gamma; Kynurenine; Mitogens; Monocytes; Neopterin; Phytohemagglutinins; Plant Extracts; Tryptophan | 2004 |
Aspirin down-regulates tryptophan degradation in stimulated human peripheral blood mononuclear cells in vitro.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Concanavalin A; Down-Regulation; Humans; Kynurenine; Leukocytes, Mononuclear; Neopterin; Phytohemagglutinins; Protein Denaturation; Salicylic Acid; Tryptophan | 2005 |
Tryptophan metabolism and oxidative stress in patients with Huntington's disease.
Topics: Adolescent; Adult; Aged; Aldehydes; Brain; Female; Humans; Huntington Disease; Kynurenine; Male; Malondialdehyde; Middle Aged; Neopterin; Nerve Growth Factors; Oxidative Stress; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Tryptophan | 2005 |
Tryptophan degradation in patients with gynecological cancer correlates with immune activation.
Topics: Adult; Age Factors; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Genital Neoplasms, Female; Humans; Immunity, Cellular; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Middle Aged; Neopterin; Tryptophan; Tryptophan Oxygenase | 2005 |
Measurement of tryptophan, kynurenine and neopterin in women with and without postpartum blues.
Topics: Adult; Austria; Depression, Postpartum; Female; Humans; Kynurenine; Labor, Obstetric; Neopterin; Postpartum Period; Pregnancy; Prevalence; Psychiatric Status Rating Scales; Time Factors; Tryptophan; Tryptophan Oxygenase | 2005 |
Resveratrol suppresses interferon-gamma-induced biochemical pathways in human peripheral blood mononuclear cells in vitro.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Concanavalin A; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Ionophores; Kynurenine; Monocytes; Neopterin; Phytohemagglutinins; Resveratrol; Stilbenes; Tryptophan; Tumor Necrosis Factor-alpha | 2005 |
Tryptophan degradation increases with stage in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Health Status; Humans; Kynurenine; Male; Middle Aged; Neopterin; Severity of Illness Index; Tryptophan | 2006 |
Tryptophan metabolism and oxidative stress in patients with chronic brain injury.
Topics: Adult; Aged; Brain Injuries; Chromatography, High Pressure Liquid; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Humans; Kynurenine; Lipid Peroxidation; Male; Middle Aged; Models, Chemical; Neopterin; Nerve Growth Factors; Oxidative Stress; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Time Factors; Tryptophan | 2006 |
Beer down-regulates activated peripheral blood mononuclear cells in vitro.
Topics: Anti-Inflammatory Agents; Beer; Cells, Cultured; Dose-Response Relationship, Drug; Down-Regulation; Humans; Immunity, Cellular; Immunosuppressive Agents; Interferon-gamma; Leukocytes, Mononuclear; Neopterin; Phytohemagglutinins; Tryptophan | 2006 |
Blood 5-hydroxytryptamine, 5-hydroxyindoleacetic acid and melatonin levels in patients with either Huntington's disease or chronic brain injury.
Topics: Administration, Oral; Aged; Biomarkers; Brain; Brain Injury, Chronic; Down-Regulation; Female; Food, Formulated; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Lipid Peroxidation; Male; Melatonin; Middle Aged; Neopterin; Oxidative Stress; Reference Values; Serotonin; Tryptophan; Up-Regulation | 2006 |
Bariatric surgery cannot prevent tryptophan depletion due to chronic immune activation in morbidly obese patients.
Topics: Adult; Bariatric Surgery; Female; Gastroplasty; Humans; Kynurenine; Male; Middle Aged; Neopterin; Obesity, Morbid; Postoperative Period; Satiety Response; Tryptophan; Tryptophan Oxygenase; Weight Loss | 2006 |
Food preservatives sodium sulfite and sorbic acid suppress mitogen-stimulated peripheral blood mononuclear cells.
Topics: Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Food Preservatives; GTP Cyclohydrolase; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Leukocytes, Mononuclear; Neopterin; Phytohemagglutinins; Sorbic Acid; Sulfites; Th1 Cells; Tryptophan | 2006 |
Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment.
Topics: 3-Hydroxyanthranilic Acid; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethacin; Kynurenic Acid; Kynurenine; Lipid Peroxidation; Male; Middle Aged; Molecular Structure; Neopterin; ortho-Aminobenzoates; Osteoporosis; Sodium Salicylate; Tryptophan | 2006 |
Vitamin C and E suppress mitogen-stimulated peripheral blood mononuclear cells in vitro.
Topics: Antioxidants; Ascorbic Acid; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Mitogens; Neopterin; Tryptophan; Vitamin E | 2007 |
Calcium-pterin suppresses mitogen-induced tryptophan degradation and neopterin production in peripheral blood mononuclear cells.
Topics: Antineoplastic Agents; Calcium; Cells, Cultured; Humans; Leukocytes, Mononuclear; Mitogens; Neopterin; Pterins; Tryptophan | 2006 |
Non-invasive monitoring of kidney allograft rejection through IDO metabolism evaluation.
Topics: Acute Disease; Adult; Aged; Creatinine; Epithelial Cells; Female; Graft Rejection; Humans; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kidney; Kidney Transplantation; Kynurenine; Male; Middle Aged; Neopterin; Tryptophan | 2007 |
Decreased serum tryptophan concentration predicts poor prognosis in malignant melanoma patients.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Disease Progression; Female; Follow-Up Studies; Humans; Male; Melanoma; Middle Aged; Neoplasm Staging; Neopterin; Prognosis; Retrospective Studies; Skin Neoplasms; Survival Rate; Tryptophan | 2007 |
Diminished quality of life in patients with cancer correlates with tryptophan degradation.
Topics: Aged; Disease Progression; Fatigue; Female; Humans; Immunity, Cellular; Karnofsky Performance Status; Kynurenine; Male; Middle Aged; Neoplasms; Neopterin; Prognosis; Quality of Life; Survival Analysis; Tryptophan | 2007 |
Inverse association between serum selenium concentrations and parameters of immune activation in patients with cardiac disorders.
Topics: Aged; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Heart Diseases; Humans; Immune System; Male; Middle Aged; Models, Statistical; Neopterin; Oxidative Stress; Reproducibility of Results; Selenium; Tryptophan | 2007 |
Plasma kynurenine and related measures in tic disorder patients.
Topics: Adolescent; Adult; Case-Control Studies; Child; Child, Preschool; Female; Humans; Hydrocortisone; Kynurenine; Male; Middle Aged; Neopterin; Tic Disorders; Tryptophan | 2007 |
Altered kynurenine metabolism correlates with infarct volume in stroke.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Brain Infarction; Chromatography, High Pressure Liquid; Female; Humans; Kynurenine; Lipid Peroxidation; Male; Models, Biological; Neopterin; Nerve Growth Factors; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Statistics as Topic; Stroke; Time Factors; Tomography, X-Ray Computed; Tryptophan | 2007 |
IFN-gamma mediated pathways in patients with fatigue and chronic active Epstein Barr virus-infection.
Topics: Adult; Antigens, Viral; Capsid Proteins; DNA, Viral; Fatigue Syndrome, Chronic; Female; Humans; Infectious Mononucleosis; Interferon-gamma; Male; Neopterin; Tryptophan; Viremia; Virus Replication | 2008 |
Quality of life and immune activation in patients with HIV-infection.
Topics: Acquired Immunodeficiency Syndrome; Adult; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Depression; Disease Progression; Female; Health Status Indicators; Hemoglobins; HIV Infections; Humans; Immunity; Kynurenine; Male; Middle Aged; Neopterin; Predictive Value of Tests; Psychological Tests; Quality of Life; Regression Analysis; Surveys and Questionnaires; Tryptophan; Viral Load | 2008 |
High serum tryptophan concentration in pollinosis patients is associated with unresponsiveness to pollen extract therapy.
Topics: Adult; Biomarkers; Desensitization, Immunologic; Enzyme-Linked Immunosorbent Assay; Female; Humans; Kynurenine; Male; Neopterin; Pollen; Rhinitis, Allergic, Seasonal; Tryptophan | 2008 |
Differential effect of type I and type II interferons on neopterin production and amino acid metabolism in human astrocyte-derived cells.
Topics: AIDS Dementia Complex; Amino Acids, Aromatic; Astrocytes; Brain; Cell Line, Tumor; HIV-1; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Interferon-gamma; Neopterin; Tryptophan | 2008 |
Stimulant use is associated with immune activation and depleted tryptophan among HIV-positive persons on anti-retroviral therapy.
Topics: Adult; Affective Symptoms; Anti-Retroviral Agents; CD4-Positive T-Lymphocytes; Cocaine; Female; HIV Infections; HIV Seropositivity; Humans; Male; Methamphetamine; Middle Aged; Neopterin; Patient Compliance; Reverse Transcriptase Polymerase Chain Reaction; Tryptophan; Viral Load | 2008 |
Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Cohort Studies; Enzyme Activation; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Irritable Bowel Syndrome; Kynurenine; Male; Middle Aged; Neopterin; Tryptophan; Young Adult | 2009 |
Delta9-tetrahydrocannabinol and cannabidiol modulate mitogen-induced tryptophan degradation and neopterin formation in peripheral blood mononuclear cells in vitro.
Topics: Cannabidiol; Cannabinoid Receptor Antagonists; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Gene Expression Regulation; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Interferon-alpha; Kynurenine; Leukocytes, Mononuclear; Lipopolysaccharides; Mitogens; Morpholines; Neopterin; Pyrazoles; Statistics, Nonparametric; Tryptophan | 2009 |
Immunomodulatory effects of Turkish propolis: changes in neopterin release and tryptophan degradation.
Topics: Cell Survival; Cytokines; Down-Regulation; Humans; Immunologic Factors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Leukocytes, Mononuclear; Neopterin; Phytohemagglutinins; Propolis; Tryptophan | 2009 |
Cacao extracts suppress tryptophan degradation of mitogen-stimulated peripheral blood mononuclear cells.
Topics: Anti-Inflammatory Agents; Antioxidants; Cacao; Cells, Cultured; Humans; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Lipopolysaccharides; Mitogens; Neopterin; Phytohemagglutinins; Plant Extracts; Seeds; Th1 Cells; Tryptophan | 2009 |
Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometry.
Topics: Biomarkers; Chromatography, Liquid; Cotinine; Cystathionine; Humans; Inflammation; Neopterin; Riboflavin; Sensitivity and Specificity; Tandem Mass Spectrometry; Tryptophan; Vitamin B 6 | 2009 |
Increased tryptophan degradation in patients with bronchus carcinoma.
Topics: Blood Sedimentation; C-Reactive Protein; Carcinoma, Non-Small-Cell Lung; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Middle Aged; Neoplasm Proteins; Neopterin; Pilot Projects; Small Cell Lung Carcinoma; Tryptophan | 2010 |
Interferon-gamma-mediated pathways are induced in human CD34(+) haematopoietic stem cells.
Topics: Anemia; Antigens, CD34; Antiviral Agents; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Chronic Disease; Dose-Response Relationship, Drug; Erythroid Precursor Cells; Erythropoiesis; GTP Cyclohydrolase; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Monocytes; Neopterin; Tryptophan | 2010 |
Cerebrospinal fluid analysis in affective and schizophrenic spectrum disorders: identification of subgroups with immune responses and blood-CSF barrier dysfunction.
Topics: Adult; Cohort Studies; Female; Humans; Immunoglobulins; International Classification of Diseases; Kynurenine; Male; Middle Aged; Mood Disorders; Neopterin; Psychiatric Status Rating Scales; Schizophrenia; Statistics, Nonparametric; Tomography, X-Ray Computed; Tryptophan | 2010 |
Regulation of myeloperoxidase-specific T cell responses during disease remission in antineutrophil cytoplasmic antibody-associated vasculitis: the role of Treg cells and tryptophan degradation.
Topics: Acute Disease; Aged; Antibodies, Antineutrophil Cytoplasmic; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunosuppressive Agents; Kynurenine; Lymphocyte Count; Male; Middle Aged; Neopterin; Peroxidase; Remission Induction; T-Lymphocytes, Regulatory; Tryptophan; Vasculitis | 2010 |
Bovine colostrum modulates immune activation cascades in human peripheral blood mononuclear cells in vitro.
Topics: Animals; Cattle; Cells, Cultured; Colostrum; Dose-Response Relationship, Immunologic; Female; Humans; Immunologic Factors; Lactoferrin; Lactose; Leukocytes, Mononuclear; Lymphocyte Activation; Neopterin; Th1 Cells; Tryptophan | 2010 |
Tryptophan metabolism in allergic rhinitis: the effect of pollen allergen exposure.
Topics: Adult; Allergens; Biomarkers; Female; Humans; Kynurenine; Male; Neopterin; Pollen; Rhinitis, Allergic, Seasonal; Tryptophan | 2010 |
LPS-induced NF-kappaB expression in THP-1Blue cells correlates with neopterin production and activity of indoleamine 2,3-dioxygenase.
Topics: Cell Line, Tumor; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lipopolysaccharides; Monocytes; Neopterin; NF-kappa B; Protein Transport; Tryptophan | 2010 |
In vitro testing for anti-inflammatory properties of compounds employing peripheral blood mononuclear cells freshly isolated from healthy donors.
Topics: Anti-Inflammatory Agents; Humans; Inflammation; Interferon-gamma; Interleukin-2 Receptor alpha Subunit; Isoprostanes; Leukocytes, Mononuclear; Mitogens; Neopterin; Receptors, Tumor Necrosis Factor, Type II; Tryptophan; Tumor Necrosis Factor-alpha | 2011 |
Enhanced tryptophan degradation in patients with ovarian carcinoma correlates with several serum soluble immune activation markers.
Topics: Adult; Aged; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interleukin-2 Receptor alpha Subunit; Interleukin-6; Kynurenine; Middle Aged; Neopterin; Ovarian Neoplasms; Receptors, Tumor Necrosis Factor; Tryptophan | 2011 |
Enhanced degradation of tryptophan in patients on hemodialysis.
Topics: Adult; Aged; Aged, 80 and over; Austria; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Enzyme Activation; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Middle Aged; Neopterin; Quality of Life; Renal Dialysis; Treatment Outcome; Tryptophan; Uremia; Young Adult | 2010 |
Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation.
Topics: Aged; Alzheimer Disease; Biomarkers; Cognition Disorders; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Neopterin; Oxidative Stress; Protein Carbonylation; Reference Values; Tryptophan; Vitamin B 12 | 2010 |
Tryptophan degradation and serum neopterin concentrations in intensive care unit patients.
Topics: Aged; APACHE; Biomarkers; Critical Care; Female; Humans; Immune System; Kynurenine; Male; Middle Aged; Multiple Organ Failure; Neopterin; Systemic Inflammatory Response Syndrome; Tryptophan | 2011 |
Chronic low-grade inflammation in elderly persons is associated with altered tryptophan and tyrosine metabolism: role in neuropsychiatric symptoms.
Topics: Aged; Aged, 80 and over; C-Reactive Protein; Chronic Disease; Enzyme-Linked Immunosorbent Assay; Fasting; Fatigue; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interleukin-6; Male; Mental Disorders; Movement Disorders; Neopterin; Nitrites; Psychiatric Status Rating Scales; Sleep Wake Disorders; Tryptophan; Tyrosine | 2011 |
Tryptophan degradation and neopterin levels in treated rheumatoid arthritis patients.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Disease Progression; Female; Humans; Kynurenine; Male; Middle Aged; Neopterin; Tryptophan; Tumor Necrosis Factor-alpha | 2012 |
Plasma kynurenine levels are elevated in suicide attempters with major depressive disorder.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Cytokines; Depressive Disorder, Major; Duloxetine Hydrochloride; Female; Humans; Hypericum; Impulsive Behavior; Inflammation; Kynurenine; Male; Middle Aged; Neopterin; Phytotherapy; Recurrence; Serotonin; Smoking; Suicide, Attempted; Thiophenes; Tryptophan; Young Adult | 2011 |
Influence of immunosuppressive agents on tryptophan degradation and neopterin production in human peripheral blood mononuclear cells.
Topics: Cells, Cultured; Cyclosporine; GTP Cyclohydrolase; Humans; Immunosuppressive Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Methylprednisolone; Mycophenolic Acid; Neopterin; Phytohemagglutinins; Sirolimus; Tacrolimus; Tryptophan | 2011 |
Determination of neopterin, kynurenine, tryptophan and creatinine in human serum by high throuput HPLC.
Topics: Buffers; Chromatography, High Pressure Liquid; Creatinine; Humans; Hydrogen-Ion Concentration; Kynurenine; Neopterin; Phosphates; Reproducibility of Results; Tryptophan | 2011 |
Kynurenine metabolism predicts cognitive function in patients following cardiac bypass and thoracic surgery.
Topics: Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Cognition; Coronary Artery Bypass; Enzyme-Linked Immunosorbent Assay; Extracorporeal Circulation; Female; Humans; Inflammation; Kynurenine; Lipid Peroxidation; Male; Middle Aged; Neopterin; Nerve Growth Factors; Neuropsychological Tests; Postoperative Complications; Predictive Value of Tests; Psychomotor Performance; Reproducibility of Results; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Stroop Test; Thoracic Surgical Procedures; Trail Making Test; Tryptophan; Tumor Necrosis Factor-alpha; Verbal Learning | 2011 |
Vitamin B6 status and interferon-γ-mediated immune activation in primary hyperparathyroidism.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Female; Humans; Hyperparathyroidism, Primary; Immunity, Cellular; Immunologic Factors; Inflammation; Interferon-gamma; Kynurenine; Longitudinal Studies; Male; Middle Aged; Monitoring, Immunologic; Neopterin; ortho-Aminobenzoates; Parathyroidectomy; Postoperative Care; Risk Factors; Tryptophan; Vitamin B 6 | 2012 |
Tryptophan, neopterin, and nitrite in allergy.
Topics: Humans; Hypersensitivity; Neopterin; Nitrites; Tryptophan | 2012 |
Assessment of immunotoxicity parameters in individuals occupationally exposed to lead.
Topics: Adult; Biomarkers; Cytokines; Genetic Association Studies; Humans; Immunosuppressive Agents; Industry; Kynurenine; Lead; Lead Poisoning; Lymphocyte Subsets; Male; Middle Aged; Neopterin; Occupational Exposure; Polymorphism, Genetic; Porphobilinogen Synthase; Portugal; Receptors, Calcitriol; Smoking; Spain; Tryptophan | 2012 |
Specific immunotherapy normalizes tryptophan concentrations in patients with allergic rhinitis.
Topics: Adult; Cytokines; Female; Humans; Immunization, Secondary; Immunotherapy; Kynurenine; Male; Neopterin; Poaceae; Pollen; Rhinitis, Allergic, Seasonal; Th1-Th2 Balance; Tryptophan; Vaccines | 2012 |
A pilot study on neopterin levels and tryptophan degradation in zinc-exposed galvanization workers.
Topics: Administration, Inhalation; Adult; Aerosols; Humans; Male; Metallurgy; Nanoparticles; Neopterin; Occupational Exposure; Pilot Projects; Tryptophan; Zinc | 2013 |
Neopterin and kynurenine-tryptophan ratio as predictors of coronary events in older adults, the Hordaland Health Study.
Topics: Aged; Biomarkers; Coronary Artery Disease; Female; Follow-Up Studies; Health Surveys; Humans; Kynurenine; Male; Neopterin; Norway; Prospective Studies; Tryptophan | 2013 |
Immunomodulatory effects in vitro of vitamin K antagonist acenocoumarol.
Topics: Acenocoumarol; Anticoagulants; Caco-2 Cells; Cell Line; Cells, Cultured; Humans; Immunologic Factors; Interferon-gamma; Interleukin-10; Leukocytes, Mononuclear; Lipopolysaccharides; Mitogens; Neopterin; NF-kappa B; Phytohemagglutinins; Tryptophan; Tumor Necrosis Factor-alpha; Vitamin K | 2013 |
A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Body Mass Index; Creatinine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Middle Aged; Motor Activity; Neopterin; Norway; ortho-Aminobenzoates; Reference Values; Smoking; Tryptophan; Xanthurenates | 2013 |
Obesity-related dysregulation of the tryptophan-kynurenine metabolism: role of age and parameters of the metabolic syndrome.
Topics: Adolescent; Adult; Age Factors; Aged; C-Reactive Protein; Child; Female; Humans; Interleukin-6; Kynurenine; Male; Metabolic Syndrome; Middle Aged; Neopterin; Obesity; Observational Studies as Topic; Tryptophan; Young Adult | 2014 |
Endocrine and immunological parameters in individuals involved in Prestige spill cleanup tasks seven years after the exposure.
Topics: Adult; Chemical Hazard Release; Endocrine Disruptors; Endocrine System; Environmental Exposure; Environmental Restoration and Remediation; Female; Humans; Hydrocortisone; Immune System; Kynurenine; Lymphocyte Subsets; Male; Neopterin; Occupational Exposure; Petroleum Pollution; Prolactin; Spain; Tryptophan | 2013 |
Lignans from Carthamus tinctorius suppress tryptophan breakdown via indoleamine 2,3-dioxygenase.
Topics: 4-Butyrolactone; Carthamus tinctorius; Cell Survival; Dose-Response Relationship, Drug; Furans; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Leukocytes, Mononuclear; Lignans; Molecular Structure; Neopterin; Plant Extracts; Plants, Medicinal; Seeds; Tryptophan | 2013 |
Exercise affects symptom severity but not biological measures in depression and somatization - results on IL-6, neopterin, tryptophan, kynurenine and 5-HIAA.
Topics: Adult; Case-Control Studies; Depression; Exercise; Female; Humans; Hydroxyindoleacetic Acid; Interleukin-6; Kynurenine; Male; Middle Aged; Neopterin; Severity of Illness Index; Somatoform Disorders; Tryptophan | 2013 |
Effects of globularifolin on cell survival, nuclear factor-κB activity, neopterin production, tryptophan breakdown and free radicals in vitro.
Topics: Antioxidants; Cell Survival; Dose-Response Relationship, Drug; Free Radicals; Humans; Immunologic Factors; Inflammation Mediators; Iridoid Glucosides; Leukemia, Monocytic, Acute; Leukocytes, Mononuclear; Lipopolysaccharides; Mitogens; Neopterin; NF-kappa B; Phytotherapy; Plant Extracts; Plantago; Tryptophan | 2014 |
TiO(2) nanoparticles and bulk material stimulate human peripheral blood mononuclear cells.
Topics: Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; Metal Nanoparticles; Monocytes; Neopterin; Titanium; Tryptophan | 2014 |
Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study.
Topics: Aged; Biomarkers; Bone Density; Female; Humans; Inflammation; Inflammation Mediators; Interferon-gamma; Kynurenine; Male; Metabolic Networks and Pathways; Metabolome; Middle Aged; Neopterin; Risk Factors; Tryptophan | 2014 |
Relation of kynurenine/tryptophan with immune and inflammatory markers in coronary artery disease.
Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Coronary Artery Disease; Enzyme-Linked Immunosorbent Assay; Female; Humans; Kynurenine; Male; Middle Aged; Neopterin; Peroxidase; Spectrophotometry, Ultraviolet; Tryptophan | 2014 |
Evidence for increased catabolism of vitamin B-6 during systemic inflammation.
Topics: Aged; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Dietary Supplements; Female; Humans; Inflammation; Kynurenine; Linear Models; Longitudinal Studies; Male; Middle Aged; Neopterin; Norway; Oxidative Stress; Pyridoxal; Pyridoxal Phosphate; Pyridoxic Acid; ROC Curve; Tryptophan; Vitamin B 6 | 2014 |
Interferon-γ-induced inflammatory markers and the risk of cancer: the Hordaland Health Study.
Topics: Adult; Aged; Biomarkers, Tumor; C-Reactive Protein; Female; Follow-Up Studies; Humans; Inflammation; Interferon-gamma; Kaplan-Meier Estimate; Kynurenine; Male; Middle Aged; Neoplasms; Neopterin; Proportional Hazards Models; Prospective Studies; Risk Factors; Tryptophan | 2014 |
Vitamins B2 and B6 as determinants of kynurenines and related markers of interferon-γ-mediated immune activation in the community-based Hordaland Health Study.
Topics: Aged; Biomarkers; Cohort Studies; Diet; Female; Humans; Immunity; Interferon-gamma; Kynurenine; Male; Middle Aged; Neopterin; Norway; Nutritional Status; Pyridoxal Phosphate; Riboflavin; Surveys and Questionnaires; Tryptophan; Vitamin B 6 | 2014 |
Lavender oil suppresses indoleamine 2,3-dioxygenase activity in human PBMC.
Topics: Acyclic Monoterpenes; Bicyclic Monoterpenes; Cells, Cultured; Cyclohexenes; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Lavandula; Leukocytes, Mononuclear; Limonene; Monoterpenes; Neopterin; Oils, Volatile; Phytohemagglutinins; Plant Extracts; Plant Oils; Terpenes; Tryptophan | 2014 |
The tryptophan kynurenine pathway, neopterin and IL-6 during vulvectomy and abdominal hysterectomy.
Topics: Adult; Aged; Biomarkers; Female; Humans; Hysterectomy; Inflammation; Interleukin-6; Kynurenine; Middle Aged; Neopterin; Prospective Studies; Tryptophan; Vulva | 2014 |
Low serum tryptophan predicts higher mortality in cardiovascular disease.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Female; Humans; Immunity; Indoleamine-Pyrrole 2,3,-Dioxygenase; Life Expectancy; Male; Middle Aged; Neopterin; Survival Analysis; Tryptophan; Young Adult | 2015 |
Coffee extracts suppress tryptophan breakdown in mitogen-stimulated peripheral blood mononuclear cells.
Topics: Anti-Inflammatory Agents; Caffeic Acids; Cells, Cultured; Chlorogenic Acid; Coffea; Gallic Acid; Humans; Immunologic Factors; Immunosuppressive Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Leukocytes, Mononuclear; Mitogens; Neopterin; Phytohemagglutinins; Plant Extracts; Serotonin; Tryptophan | 2015 |
Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer.
Topics: Antibodies, Bacterial; Biomarkers, Tumor; Case-Control Studies; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Helicobacter Infections; Helicobacter pylori; Humans; Immunoglobulin G; Kynurenine; Male; Middle Aged; Neopterin; Prospective Studies; Tryptophan; Tumor Escape | 2015 |
The kynurenine pathway activities in a sub-Saharan HIV/AIDS population.
Topics: Acquired Immunodeficiency Syndrome; Adult; Africa South of the Sahara; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Count; Cross-Sectional Studies; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gas Chromatography-Mass Spectrometry; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interferon-gamma; Interleukin-6; Kynurenine; Male; Middle Aged; Neopterin; Niacinamide; Pentosyltransferases; Poverty; Quinolinic Acid; South Africa; Tryptophan | 2015 |
Bisphenol A suppresses Th1-type immune response in human peripheral blood mononuclear cells in vitro.
Topics: Benzhydryl Compounds; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Interferon-gamma; Leukocytes, Mononuclear; Neopterin; NF-kappa B; Phenols; Phytohemagglutinins; Th1 Cells; Tryptophan | 2015 |
Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease.
Topics: 3-Hydroxyanthranilic Acid; Aged; Animals; Biomarkers; Body Mass Index; Cholesterol; Coronary Artery Disease; Cross-Sectional Studies; Energy Intake; Fatty Acids, Omega-3; Female; Fishes; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Neopterin; Norway; Nutrition Assessment; ortho-Aminobenzoates; Seafood; Triglycerides; Tryptophan; Xanthurenates | 2017 |
Fast and sensitive HPLC method for the determination of neopterin, kynurenine and tryptophan in amniotic fluid, malignant effusions and wound exudates.
Topics: Amniotic Fluid; Chromatography, High Pressure Liquid; Exudates and Transudates; Humans; Kynurenine; Neopterin; Pleural Effusion, Malignant; Spectrophotometry, Ultraviolet; Tryptophan; Wound Healing | 2015 |
Central kynurenine pathway shift with age in women.
Topics: Adult; Aged; Aged, 80 and over; Aging; Brain; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Middle Aged; Neopterin; Neurotoxins; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Young Adult | 2016 |
Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality: The Hordaland Health Study.
Topics: Aged; Biomarkers; C-Reactive Protein; Female; Humans; Inflammation; Kynurenine; Longitudinal Studies; Male; Middle Aged; Mortality; Neopterin; Norway; Tryptophan | 2016 |
Tryptophan depletion in context of the inflammatory and general nutritional status of a low-income South African HIV-infected population.
Topics: Adult; Antiretroviral Therapy, Highly Active; Biomarkers; Black People; CD4 Lymphocyte Count; Cross-Sectional Studies; Deficiency Diseases; Diet; Female; Food Supply; HIV Infections; Hospitals, Public; Humans; Male; Middle Aged; Neopterin; Nutritional Status; Outpatient Clinics, Hospital; Poverty Areas; South Africa; Suburban Health Services; Tryptophan | 2016 |
Relationship between indoleamine 2,3-dioxygenase activity and lymphatic invasion propensity of colorectal carcinoma.
Topics: Biomarkers, Tumor; Biopterins; Carcinoma; Case-Control Studies; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lymphatic Metastasis; Lymphatic System; Male; Middle Aged; Neoplasm Invasiveness; Neopterin; Predictive Value of Tests; Tryptophan; Urinalysis | 2016 |
Effects of Exhaustive Aerobic Exercise on Tryptophan-Kynurenine Metabolism in Trained Athletes.
Topics: Adult; Athletes; Biomarkers; Exercise; Fatigue; Female; Humans; Immune System; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Metabolism; Neopterin; Oxygen; Tryptophan; Tyrosine | 2016 |
Neopterin Release and Tryptophan Degradation in Patients with Uveitis.
Topics: Adolescent; Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Immunity, Cellular; Male; Middle Aged; Neopterin; Prospective Studies; T-Lymphocytes; Tryptophan; Uveitis; Young Adult | 2016 |
Maternal plasma total neopterin and kynurenine/tryptophan levels during pregnancy in relation to asthma development in the offspring.
Topics: Adult; Asthma; Child; Drug Prescriptions; Female; Humans; Interferon-gamma; Kynurenine; Neopterin; Norway; Pregnancy; Tryptophan | 2016 |
Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Female; Humans; Inflammation; Interleukin-10; Kynurenine; Linear Models; Male; Neopterin; ortho-Aminobenzoates; Pyridoxal Phosphate; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Young Adult | 2016 |
LC-MS/MS-based quantification of kynurenine metabolites, tryptophan, monoamines and neopterin in plasma, cerebrospinal fluid and brain.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Humans; Kynurenine; Mice, Inbred C57BL; Neopterin; ortho-Aminobenzoates; Quinolinic Acid; Signal Transduction; Tandem Mass Spectrometry; Tryptophan | 2016 |
Resveratrol intake enhances indoleamine-2,3-dioxygenase activity in humans.
Topics: Administration, Oral; Adult; Biomarkers; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Neopterin; Pilot Projects; Resveratrol; Stilbenes; Tryptophan; Young Adult | 2016 |
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female; Glomerular Filtration Rate; Humans; Hydrocortisone; Indican; Indoleacetic Acids; Inflammation; Kynurenic Acid; Male; Middle Aged; Neopterin; Oxidative Stress; Pilot Projects; Prospective Studies; Renal Insufficiency, Chronic; Surveys and Questionnaires; Tasmania; Tryptophan | 2016 |
Predictive and prognostic role of serum neopterin and tryptophan breakdown in prostate cancer.
Topics: Adult; Aged; Biomarkers, Tumor; Humans; Kaplan-Meier Estimate; Kynurenine; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neopterin; Outcome Assessment, Health Care; Postoperative Period; Predictive Value of Tests; Preoperative Period; Prognosis; Proportional Hazards Models; Prostate-Specific Antigen; Prostatectomy; Prostatic Neoplasms; ROC Curve; Tryptophan | 2017 |
The Relationship of Kynurenine and Neopterin Levels and Their Association with a Selection of Other Immune Markers in Chronic Myeloid Leukaemia Patients.
Topics: Adult; Aged; Biomarkers; C-Reactive Protein; Case-Control Studies; Female; Humans; Interleukin-6; Kynurenine; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocyte Count; Linear Models; Male; Middle Aged; Neopterin; Tryptophan; Young Adult | 2016 |
Possible changes of New-Generation inflammation markers with occupational lead exposure.
Topics: Adult; Biomarkers; Chromatography, High Pressure Liquid; Hospitals; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Lead; Male; Middle Aged; Neopterin; Occupational Exposure; Tryptophan; Turkey | 2017 |
The role of tryptophan metabolism and food craving in the relationship between obesity and bipolar disorder.
Topics: Adult; Bipolar Disorder; Body Mass Index; Craving; Eating; Energy Metabolism; Female; Food; Humans; Kynurenine; Lipid Metabolism; Male; Middle Aged; Neopterin; Nitrites; Obesity; Sex Factors; Tryptophan; Waist-Hip Ratio | 2018 |
Nitrite, neopterin levels and tryptophan degradation in allergic conjunctivitis.
Topics: Adolescent; Adult; Biomarkers; Conjunctivitis, Allergic; Female; Humans; Male; Neopterin; Nitrites; Severity of Illness Index; Tryptophan; Young Adult | 2018 |
Total sleep time and kynurenine metabolism associated with mood symptom severity in bipolar disorder.
Topics: Adult; Affect; Biomarkers; Bipolar Disorder; Depression; Female; Humans; Inflammation; Kynurenine; Male; Middle Aged; Neopterin; Outcome Assessment, Health Care; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Tryptophan | 2018 |
Associations Among Obesity, Inflammation, and Tryptophan Catabolism in Pregnancy.
Topics: Adult; Biomarkers; Body Mass Index; Cross-Sectional Studies; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Male; Neopterin; Obesity; Pregnancy; Pregnancy Complications; Tryptophan | 2018 |
Immunobiochemical pathways of neopterin formation and tryptophan breakdown via indoleamine 2,3-dioxygenase correlate with circulating tumor cells in ovarian cancer patients- A study of the OVCAD consortium.
Topics: Carcinoma, Ovarian Epithelial; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Middle Aged; Neoplasms, Glandular and Epithelial; Neoplastic Cells, Circulating; Neopterin; Ovarian Neoplasms; Tryptophan | 2018 |
Immunomodulatory Effects of Diterpene Quinone Derivatives from the Roots of
Topics: Cells, Cultured; Diterpenes; Humans; Immunologic Factors; Kynurenine; Lamiaceae; Leukocytes, Mononuclear; Neopterin; Plant Extracts; Plant Roots; Quinones; Tryptophan | 2018 |
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction.
Topics: Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Endothelium; Feces; Female; Gastrointestinal Microbiome; HIV Infections; Humans; Inflammation; Kynurenine; Male; Metabolism; Middle Aged; Neopterin; Risk Factors; RNA, Ribosomal, 16S; Tryptophan | 2018 |
Tryptophan Degradation and Antioxidant Status in Patients With Thyroid Disorders.
Topics: Adult; Antioxidants; Biomarkers; Case-Control Studies; Catalase; Female; Humans; Kynurenine; Male; Middle Aged; Neopterin; Thyroid Diseases; Thyroid Gland; Tryptophan | 2018 |
Immunological alterations in frail older adults: A cross sectional study.
Topics: Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Female; Frail Elderly; Frailty; Humans; Kynurenine; Logistic Models; Male; Multivariate Analysis; Neopterin; Phenylalanine; Reproducibility of Results; Tryptophan | 2018 |
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections.
Topics: Adult; Aged; Case-Control Studies; Central Nervous System Infections; Chromatography, Liquid; Correlation of Data; Cross-Sectional Studies; Cytokines; Female; Humans; Kynurenine; Male; Middle Aged; Neopterin; Retrospective Studies; Tandem Mass Spectrometry; Tryptophan; Young Adult | 2018 |
Neopterin Levels and Indoleamine 2,3-Dioxygenase Activity as Biomarkers of Immune System Activation and Childhood Allergic Diseases.
Topics: Adolescent; Asthma; Biomarkers; Child; Child, Preschool; Dermatitis, Atopic; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypersensitivity; Immune System; Immunoglobulin E; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infant; Kynurenine; Male; Neopterin; Prospective Studies; Rhinitis, Allergic; Tryptophan | 2019 |
The kynurenine pathway and cognitive performance in community-dwelling older adults. The Hordaland Health Study.
Topics: Aged; Biomarkers; Body Mass Index; C-Reactive Protein; Cognition; Cross-Sectional Studies; Female; Humans; Independent Living; Inflammation; Kynurenine; Male; Neopterin; Neuropsychological Tests; Signal Transduction; Tryptophan | 2019 |
Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma-Application to Clinical and Epidemiology Cohorts.
Topics: Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Citrulline; Cohort Studies; Colitis, Ulcerative; Female; Humans; Kynurenine; Male; Middle Aged; Neopterin; Quality Control; Serotonin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tryptophan; Young Adult | 2019 |
Circulating markers of cellular immune activation in prediagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3).
Topics: Adenocarcinoma of Lung; Adult; Aged; Biomarkers, Tumor; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Case-Control Studies; Female; Follow-Up Studies; Humans; Inflammation; Kynurenine; Lung Neoplasms; Male; Middle Aged; Neopterin; Prognosis; Prospective Studies; Risk Factors; Small Cell Lung Carcinoma; Tryptophan | 2020 |
Tryptophan metabolic pathway and neopterin in asthmatic children in clinical practice.
Topics: Adolescent; Asthma; Case-Control Studies; Child; Cross-Sectional Studies; Female; Humans; Male; Metabolic Networks and Pathways; Neopterin; Tryptophan | 2019 |
Assessment of neopterin and indoleamine 2,3-dioxygenase activity in patients with seasonal influenza: A pilot study.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Hospitalization; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Influenza, Human; Kynurenine; Male; Middle Aged; Neopterin; Pilot Projects; Pneumonia; Retrospective Studies; ROC Curve; Tryptophan | 2019 |
Abdominal Adipose Tissue Is Associated With Alterations in Tryptophan-Kynurenine Metabolism and Markers of Systemic Inflammation in People With Human Immunodeficiency Virus.
Topics: Abdominal Fat; Aged; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Female; HIV; HIV Infections; Humans; Inflammation; Kynurenic Acid; Kynurenine; Longitudinal Studies; Male; Middle Aged; Neopterin; Quinolinic Acid; Tryptophan; Waist-Hip Ratio | 2020 |
Neopterin levels and Kyn/Trp ratios were significantly increased in dengue virus patients and subsequently decreased after recovery.
Topics: Adolescent; Adult; Child; Dengue; Dengue Virus; Female; Follow-Up Studies; Humans; Kynurenine; Male; Middle Aged; Neopterin; RNA, Viral; Tryptophan; Young Adult | 2020 |
Cerebrospinal Fluid Neurofilament Light Chain Is Associated with Kynurenine Pathway Metabolite Changes in Multiple Sclerosis.
Topics: Biomarkers; Brain; Enzyme-Linked Immunosorbent Assay; Humans; Kynurenine; Mass Spectrometry; Metabolic Networks and Pathways; Metabolomics; Multiple Sclerosis; Neopterin; Neurofilament Proteins; ROC Curve; Tryptophan | 2020 |
Neopterin and biopterin levels and tryptophan degradation in patients with diabetes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopterins; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Kynurenine; Male; Metformin; Middle Aged; Neopterin; Tryptophan; Vildagliptin; Young Adult | 2020 |
Serum neopterin levels in relation to mild and severe COVID-19.
Topics: Adult; Aged; Biomarkers; COVID-19; Critical Care; Female; Hospitalization; Humans; Kynurenine; Male; Middle Aged; Neopterin; Pandemics; Prognosis; SARS-CoV-2; Tryptophan | 2020 |
Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis.
Topics: Biomarkers; Cholangitis, Sclerosing; Chromatography, Liquid; Cross-Sectional Studies; Humans; Kynurenine; Neopterin; Tandem Mass Spectrometry; Tryptophan | 2021 |
Decreasing Tryptophan and Increasing Neopterin Plasma Levels During Pregnancy are Associated with High First Trimester
Topics: Adult; Female; Humans; Immunoglobulin G; Neopterin; Porphyromonas gingivalis; Pregnancy; Pregnancy Trimester, First; Tryptophan | 2022 |
Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developing a prognostic multivariate model.
Topics: Amino Acids; Arginine; Carcinoma, Non-Small-Cell Lung; Glycine; Humans; Immune Checkpoint Inhibitors; Leukocytes, Mononuclear; Lung Neoplasms; Neopterin; Pilot Projects; Prognosis; Quinolinic Acids; Tryptophan | 2022 |
Tryptophan-kynurenine metabolism during acute alcohol withdrawal in patients with alcohol use disorder: The role of immune activation.
Topics: Alcohol Drinking; Alcoholism; Biomarkers; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Neopterin; Quinolinic Acid; Substance Withdrawal Syndrome; Tryptophan | 2022 |
Associations of microbial and indoleamine-2,3-dioxygenase-derived tryptophan metabolites with immune activation in healthy adults.
Topics: Acute-Phase Reaction; Adult; Biomarkers; C-Reactive Protein; Chemokine CXCL10; Cytokines; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Interleukin-10; Interleukin-6; Kynurenine; Leukocytes, Mononuclear; Lipopolysaccharides; Neopterin; Receptors, Aryl Hydrocarbon; RNA, Ribosomal, 16S; Tryptophan; Tumor Necrosis Factor-alpha | 2022 |
A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium.
Topics: Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Humans; Inflammation; Interferon-gamma; Kynurenine; Lung Neoplasms; NAD; Neopterin; Tryptophan | 2023 |
CSF neopterin, quinolinic acid and kynurenine/tryptophan ratio are biomarkers of active neuroinflammation.
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Humans; Infant; Inflammation; Kynurenine; Leukocytosis; Male; Neopterin; Nervous System Diseases; Neuroinflammatory Diseases; Quinolinic Acid; Tryptophan | 2023 |
Neopterin and kynurenine in serum and urine as prognostic biomarkers in hospitalized patients with delta and omicron variant SARS-CoV-2 infection.
Topics: Biomarkers; COVID-19; Humans; Kynurenine; Neopterin; Oxygen; Prognosis; SARS-CoV-2; Tryptophan | 2023 |