tryptophan and nadp

tryptophan has been researched along with nadp in 138 studies

Research

Studies (138)

TimeframeStudies, this research(%)All Research%
pre-199069 (50.00)18.7374
1990's24 (17.39)18.2507
2000's25 (18.12)29.6817
2010's15 (10.87)24.3611
2020's5 (3.62)2.80

Authors

AuthorsStudies
Badawy, AA; Evans, M2
Obrebska, M; Wrońska-Nofer, T1
Brochon, JC; Iwatsubo, M; Jallon, JM; Wahl, PH1
Dalziel, K; Macfarlane, N; Mathews, B1
Bertino, JR; Greenfield, NJ; Gupta, SV; Makulu, DR; Moroson, BA; Poe, M; Williams, MN1
Birdsall, B; Burgen, AS; Feeney, J; Griffiths, DV; Kimber, BJ; King, RW; Roberts, GC; Scudder, P1
Badawy, AA2
Brochon, JC; Iwatsubo, M; Jallon, JM; Wahl, P1
Verjee, ZH1
Matthews, DA1
Shibata, Y1
Badawy, AA; Evans, M; Punjani, NF1
Williams, MN1
Berry, A; Deonarain, MP; Perham, RN; Scrutton, NS1
Rao, CM; Zigler, JS1
Amino, N; Asari, S; Fushimi, R; Hayashi, S; Kimura, S; Miyai, K; Yamaguchi, Y1
Bender, DA2
Brown, KA; Farnum, MF; Howell, EE; Kraut, J; Warren, MS1
Appleman, JR; Beard, WA; Blakley, RL; Delcamp, TJ; Freisheim, JH; Huang, SM1
Beninger, RJ; Boegman, RJ; Jhamandas, K1
Davis, DJ1
Fu, CS; Jacob, RA; McKee, RW; Swendseid, ME1
Aoki, N; Inoue, K; Sanada, H; Wada, O1
Bender, DA; Olufunwa, R1
Birdsall, B; Feeney, J; Hammond, SJ; Roberts, GC; Searle, MS1
Bulger, WH; Kupfer, D; Nanni, FJ1
Kanoh, T; Mizoguchi, I; Suzuki, T1
Armenian, AG; Gasparian, VK; Mardanian, SS1
Mardanian, SS; Sarkisova, EG1
Frydman, B; Frydman, RB; Tomaro, ML2
Orrenius, S; Schenkman, JB; von Bahr, C; Wilson, BJ1
Holmgren, A1
Nath, MC; Shastri, NV1
Dunlap, RB; Liu, JK1
Grimm, U; Knapp, A; Schmitz, KW; Schmitz, W; Schulz, M; Smetan, M1
Oguri, S1
Kaseda, H; Kido, R; Ora, H1
Berry, LJ1
Maayan, ML; Rosenberg, IN1
Sawyer, B; Slater, TF; Sträuli, U1
Haljasmaa, O; Ross, SB1
Cho-Chung, YS; Pitot, HC1
DeMoss, RD; Jean, M1
Kindl, H1
Ceauşi, G; Dumitrescu, C1
Gholson, RK1
Greengard, P; Kalinsky, H; Manning, TJ; Zak, SB1
Kulberg, AY; Schanin, SS; Tarkchanova, IA1
Freisheim, JH; Huennekens, FM1
Masana, Y; Nakagawa, I; Suzuki, T; Takahashi, T1
Anderson, JA; Hsu, JC1
Sourkes, TL1
D'Souza, L; Freisheim, JH1
Powanda, MC; Wannemacher, RW1
Jansson, I; Orrenius, S; Ramstad, E; Wilson, BJ1
Teuscher, G1
Friedrich, B; Schlegel, HG1
Friedman, PA; Kappelman, AH; Kaufman, S1
Cross, DG; Fisher, HF; McGregor, LL1
Brody, S1
Ohguri, S1
Sano, K; Shin, M; Umezawa, C2
Bender, DA; Magboul, BI1
Bender, DA; Totoe, L1
Rao, BS; Satyanarayana, U1
Babu, P; Siddiqui, SS1
Marquardt, RR; Park, IK1
Blakley, RL; Cocco, L; Groff, JP; London, RE1
Delcamp, TJ; Freisheim, JH; Li, H; Meiering, EM; Wagner, G1
Bohren, KM; Ehrig, T; Gabbay, KH; Prendergast, FG1
Chatterjee, IB; Mukhopadhyay, CK1
Frieden, C; Hoeltzli, SD2
Baker, DH; Oduho, GW1
Rao, MB; Rawat, UB1
Li, B; Lin, SX1
Jez, JM; Penning, TM; Schlegel, BP1
Chekulayev, V; Chekulayeva, L; Kahru, A; Shevchuk, I1
Vekshin, NL1
Ma, H; Penning, TM; Ratnam, K1
Adak, S; Crane, BR; Crooks, C; Getzoff, ED; Stuehr, DJ; Tainer, JA; Wang, Q1
Cotton, NP; Jackson, JB; Peake, SJ; Venning, JD1
Bradrick, TD; Howell, EE; Seo, HS; West, FW1
Daff, S; Sagami, I; Sato, Y; Shimizu, T1
Iwakura, M; Maki, K; Nakamura, T; Yamane, C1
Feyereisen, R; Murataliev, MB1
Doehr, O; Gutierrez, A; Paine, M; Roberts, GC; Scrutton, NS; Wolf, CR1
Jackson, JB; Quirk, PG; Rodrigues, DJ; Venning, JD1
Hubbard, PA; Kasper, CB; Kim, JJ; Paschke, R; Shen, AL1
Fukuwatari, T; Shibata, K; Sugimoto, E1
Fukuwatari, T; Fushiki, T; Ishihara, K; Shibata, K; Sugimoto, E1
Casaus, JL; De la Rosa, MA; Gómez-Moreno, C; Hervás, M; Lostao, A; Medina, M; Navarro, JA; Sancho, J1
Fukuwatari, T; Shibata, K; Sugimoto, E; Suzuki, Y1
Fukuwatari, T; Morikawa, Y; Shibata, K; Sugimoto, E1
Broos, J; Gabellieri, E; Jackson, JB; Strambini, GB; van Boxel, GI1
NEMETH, AM1
HJELT, L; LAHIKAINEN, T; OHMAN, S; VISAKORPI, JK1
BROWN, FC1
Harper, AE; Savage, JR1
HATANAKA, M; HAYAISHI, O; KUNO, S; KURIHARA, N; NAKAJIMA, M; TANIUCHI, H1
GREENGARD, P; QUINN, GP; REID, MB1
Fukuwatari, T; Sasaki, R; Shibata, K; Wada, H1
Dick, RA; Kensler, TW1
Munro, AW; Neeli, R; Roitel, O; Scrutton, NS1
Barbier, GG; Campbell, WH; Fischer, K; Hecht, HJ; Mendel, RR; Schwarz, G1
Panda, K; Santolini, J; Stuehr, DJ; Wang, Q; Wang, ZQ; Wei, CC1
Finazzi, G; Hippler, M; Sommer, F1
Fukuwatari, T; Kimtjra, N; Ohta, M; Sasaki, R; Shibata, K1
van der Donk, WA; Woodyer, R; Zhao, H1
Denev, ID; Minkov, IN; Sundqvist, C; Yahubyan, GT1
Ellis, EM; Lapthorn, AJ; Zhu, X1
Bhakuni, V; Singh, K1
Fukuwatari, T; Okuno, A; Shibata, K; Takahashi, K1
Lee, AL; Mauldin, RV1
Breicha, K; Hummel, W; Niefind, K; Richter, N1
Gustafsson, FS; Meints, CE; Scrutton, NS; Wolthers, KR1
Bhattacharyya, S; Das, AK; Dutta, D1
Kawagoe, Y; Makino, Y; Oshita, S; Oto, N; Sugiyama, J; Yoshimura, M1
Meints, CE; Simtchouk, S; Wolthers, KR1
Badieyan, S; Ellerbrock, J; Han, A; Robinson, RM; Sobrado, P1
Doi, K; Mutaguchi, Y; Ogura, R; Ohshima, T; Wakamatsu, T1
Chandra, S; Doharey, PK; Saxena, JK; Siddiqi, MI; Suthar, MK; Verma, A1
Louder, A; Meints, CE; Mothersole, RG; Wolthers, KR1
Essen, LO; Geisselbrecht, Y; Ignatz, E; Kiontke, S1
Banerjee, D; Immanuel, SRC; Raghunathan, A; Rajankar, MP1
Gadhave, K; Giri, R; Kalita, P; Shukla, H; Tripathi, T1
Cao, R; Periasamy, A; Rehman Alam, S; Siller, K; Wallrabe, H1
Ding, Y; Zuo, R1
Arnold, JM; Bader, DA; Cao, Q; Coarfa, C; Devarakonda, V; Donepudi, SR; Dubrulle, J; Jain, AK; Karanam, B; Kavuri, SM; Lotan, Y; Ma, J; Maity, S; McGuire, SE; Putluri, N; Putluri, V; Rajapakshe, K; Sikora, AG; Sreekumar, A; Stossi, F; Vantaku, V; Villanueva, H; von Rundstedt, FC1
Anderson, JF; Dahmani, M; Neelakanta, G; Sultana, H1
Fabara, AN; Fraaije, MW1
Aleksandrov, A; Seo, D; Vos, MH; Zhuang, B1
Chailyan, SG; Danielyan, KE; Ginosyan, SV; Grabski, HV; Tiratsuyan, SG1

Reviews

4 review(s) available for tryptophan and nadp

ArticleYear
The functions and regulation of tryptophan pyrrolase.
    Life sciences, 1977, Sep-15, Volume: 21, Issue:6

    Topics: Allosteric Regulation; Aminolevulinic Acid; Animals; Dactinomycin; Feedback; Gluconeogenesis; Heme; Kinetics; Kynurenine; Liver; NAD; NADP; Rats; Tryptophan; Tryptophan Oxygenase

1977
On the significance of drug-induced spectral changes in liver microsomes.
    Biochemical Society symposium, 1972, Volume: 34

    Topics: Alkaloids; Amphetamine; Aniline Compounds; Animals; Binding Sites; Cytochrome P-450 Enzyme System; Desipramine; Hexobarbital; Hydroxylation; Microsomes, Liver; NADP; Nortriptyline; Oxidoreductases; Phenacetin; Rats; Spectrum Analysis; Testosterone; Tryptophan

1972
[Physiopathology of the nutritional imbalance caused by deficiency of vitamin PP].
    Medicina interna, 1968, Volume: 20, Issue:3

    Topics: Amino Acids; Animals; Avitaminosis; Humans; NAD; NADP; Niacinamide; Pellagra; Tryptophan

1968
Tryptophan and niacin nutrition--is there a problem?
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Adult; Animals; Cognition Disorders; Environmental Exposure; Humans; Hydrolases; Iron Deficiencies; Kynurenine 3-Monooxygenase; Lead Poisoning; Liver; Mixed Function Oxygenases; NAD; NADP; Neoplasms; Niacin; Nutritional Requirements; Oxidative Stress; Trace Elements; Tryptophan; Zinc

1996

Other Studies

134 other study(ies) available for tryptophan and nadp

ArticleYear
The effects of acute and chronic nicotine hydrogen (+)-tartrate administration and subsequent withdrawal on rat liver tryptophan pyrrolase activity and their comparison with those of morphine, phenobarbitone and ethanol.
    The Biochemical journal, 1975, Volume: 148, Issue:3

    Topics: Animals; Cycloheximide; Dactinomycin; Ethanol; Humans; Hydrocortisone; Liver; Male; Morphine; NADP; Nicotinyl Alcohol; Phenobarbital; Premedication; Pyridines; Rats; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Oxygenase

1975
Studies on the rate of incorporation of tryptophan into nicotinamide-adenine dinucleotides in rats chronically exposed to carbon disulphide.
    Biochemical pharmacology, 1976, Jun-15, Volume: 25, Issue:12

    Topics: Animals; Carbon Disulfide; Kinetics; Liver; NAD; NADP; Rats; Tryptophan

1976
Pulse fluorimetry study of beef liver glutamate dehydrogenase reduced nicotinamide adenine dinucleotide phosphate complexes.
    Biochemistry, 1976, Jul-27, Volume: 15, Issue:15

    Topics: Animals; Binding Sites; Cattle; Glutamate Dehydrogenase; Guanosine Triphosphate; Liver; Macromolecular Substances; NADP; Protein Binding; Spectrometry, Fluorescence; Tryptophan

1976
The purification and properties of NADP-dependent isocitrate dehydrogenase from ox-heart mitochondria.
    European journal of biochemistry, 1977, Apr-15, Volume: 74, Issue:3

    Topics: Amino Acids; Animals; Cattle; Isocitrate Dehydrogenase; Kinetics; Mitochondria, Muscle; Molecular Weight; Myocardium; NADP; Spectrometry, Fluorescence; Tryptophan

1977
Dihydrofolate reductase from a resistant subline of the L1210 lymphoma. Purification by affinity chromatography and ultraviolet difference spectrophotometric and circular dichroic studies.
    Biochemistry, 1977, Jul-12, Volume: 16, Issue:14

    Topics: Animals; Chromatography, Affinity; Circular Dichroism; Drug Resistance; Leukemia L1210; Methotrexate; Molecular Weight; NADP; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase; Tryptophan

1977
19 Fnuclear magnetic resonance studies of ligand binding to 3-fluorotyrosine-and 6-fluorotryptophan-containing dihydrofolate reductase from Lactobacillus casei.
    Biochemistry, 1977, Jul-26, Volume: 16, Issue:15

    Topics: Binding Sites; Hydrogen-Ion Concentration; Lacticaseibacillus casei; Ligands; Magnetic Resonance Spectroscopy; NADP; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tryptophan; Tyrosine

1977
Pulse fluorimetry study of energy transfers between tryptophan residues and NADPH in beef liver glutamate dehydrogenase complexes.
    Biochimica et biophysica acta, 1977, Dec-23, Volume: 462, Issue:3

    Topics: Chemical Phenomena; Chemistry; Energy Transfer; Fluorometry; Glutamate Dehydrogenase; In Vitro Techniques; Liver; Mathematics; NADP; Tryptophan

1977
Tryptophan metabolism in baboons: effect of riboflavin and pyridoxine deficiency.
    Acta vitaminologica et enzymologica, 1975, Volume: 29, Issue:1-6

    Topics: 11-Hydroxycorticosteroids; Animals; Erythrocytes; Haplorhini; Kynurenine; Male; NAD; NADP; Papio; Riboflavin Deficiency; Tryptophan; Vitamin B 6 Deficiency

1975
Interpretation of nuclear magnetic resonance spectra for Lactobacillus casei dihydrofolate reductase based on the X-ray structure of the enzyme-methotrexate-NADPH complex.
    Biochemistry, 1979, Apr-17, Volume: 18, Issue:8

    Topics: Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Methotrexate; Models, Molecular; NADP; Protein Binding; Protein Conformation; Tetrahydrofolate Dehydrogenase; Tryptophan; X-Ray Diffraction

1979
On the regulation of tryptophan metabolism "via" kynurenine.
    Acta vitaminologica et enzymologica, 1978, Volume: 32, Issue:5-6

    Topics: Animals; Hydrogen-Ion Concentration; Hydroxyindoleacetic Acid; Hydroxylation; Kynurenine; Mixed Function Oxygenases; NAD; NADP; Nicotinic Acids; ortho-Aminobenzoates; Phenylalanine; Rats; Serotonin; Solubility; Tryptophan; Xanthurenates

1978
Prevention by pyrazole of the effects of chronic ethanol administration on the redox states of the hepatic nicotinamide--adenine dinucleotide (phosphate) couples and on liver and brain tryptophan metabolism in the rat.
    The Biochemical journal, 1979, Oct-15, Volume: 184, Issue:1

    Topics: Animals; Brain; Ethanol; Liver; Male; NAD; NADP; Oxidation-Reduction; Pyrazoles; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1979
Effect of N-bromosuccinimide modification on dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli. Activity, spectrophotometric, fluorescence and circular dichroism studies.
    The Journal of biological chemistry, 1975, Jan-10, Volume: 250, Issue:1

    Topics: Amino Acids; Binding Sites; Circular Dichroism; Drug Resistance, Microbial; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Methotrexate; NADP; Oxidation-Reduction; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Succinimides; Sulfhydryl Compounds; Tetrahydrofolate Dehydrogenase; Tryptophan

1975
Cooperativity induced by a single mutation at the subunit interface of a dimeric enzyme: glutathione reductase.
    Science (New York, N.Y.), 1992, Nov-13, Volume: 258, Issue:5085

    Topics: Base Sequence; Binding Sites; Escherichia coli; Genes, Bacterial; Glutathione; Glutathione Reductase; Glycine; Kinetics; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; NADP; Plasmids; Protein Multimerization; Tryptophan

1992
Levels of reduced pyridine nucleotides and lens photodamage.
    Photochemistry and photobiology, 1992, Volume: 56, Issue:4

    Topics: Animals; Guinea Pigs; In Vitro Techniques; Lens, Crystalline; NAD; NADP; Oxidation-Reduction; Rabbits; Rana catesbeiana; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Tryptophan; Ultraviolet Rays; Xenopus

1992
New enzymatic method with tryptophanase for determining potassium in serum.
    Clinical chemistry, 1992, Volume: 38, Issue:1

    Topics: Ammonia; Escherichia coli; Glutamate Dehydrogenase; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ketoglutaric Acids; NADP; Potassium; Pyridoxal Phosphate; Tryptophan; Tryptophanase

1992
Inhibition of tryptophan----niacin metabolism by dietary leucine and by leucine and 2-oxo-isocaproate in vitro.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Cells, Cultured; Depression, Chemical; Dietary Proteins; Keto Acids; Kynurenine; Leucine; Liver; NADP; Niacin; Niacinamide; Pellagra; Rats; Tryptophan; Xanthurenates

1991
Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
    Biochemistry, 1991, Nov-19, Volume: 30, Issue:46

    Topics: Coenzymes; Deuterium; Escherichia coli; Histidine; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Mutagenesis, Site-Directed; NADP; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Tryptophan

1991
Role of the conserved active site residue tryptophan-24 of human dihydrofolate reductase as revealed by mutagenesis.
    Biochemistry, 1991, Feb-05, Volume: 30, Issue:5

    Topics: Allosteric Regulation; Apoenzymes; Binding Sites; Humans; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Ligands; Mutation; NADP; Phenylalanine; Protein Denaturation; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates; Tryptophan

1991
Neurotoxicity of tryptophan metabolites.
    Annals of the New York Academy of Sciences, 1990, Volume: 585

    Topics: Animals; Cerebral Cortex; Choline O-Acetyltransferase; Kynurenic Acid; Male; NADP; Nervous System Diseases; Neurons; Picolinic Acids; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan

1990
Tryptophan fluorescence studies of ferredoxin:NADP reductase indicate the presence of tryptophan in or near the ferredoxin binding site.
    Archives of biochemistry and biophysics, 1990, Volume: 276, Issue:1

    Topics: Binding Sites; Ferredoxin-NADP Reductase; Ferredoxins; Kinetics; NADH, NADPH Oxidoreductases; NADP; Plants; Spectrometry, Fluorescence; Tryptophan

1990
Biochemical markers for assessment of niacin status in young men: levels of erythrocyte niacin coenzymes and plasma tryptophan.
    The Journal of nutrition, 1989, Volume: 119, Issue:12

    Topics: Adult; Biomarkers; Diet; Erythrocytes; Food, Fortified; Humans; Leucine; Male; NAD; NADP; Niacin; Nutritional Status; Tryptophan

1989
Effects of dietary pyrazinamide, tryptophan, or nicotinic acid and gamma-ray irradiation on levels of NAD and NADP in various organs of mice.
    Journal of nutritional science and vitaminology, 1989, Volume: 35, Issue:5

    Topics: Animals; Eating; Female; Gamma Rays; Mice; Mice, Inbred C3H; NAD; NADP; Niacin; Organ Specificity; Pyrazinamide; Thymus Gland; Tryptophan

1989
Utilization of tryptophan, nicotinamide and nicotinic acid as precursors for nicotinamide nucleotide synthesis in isolated rat liver cells.
    The British journal of nutrition, 1988, Volume: 59, Issue:2

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Male; NAD; NADP; Niacin; Niacinamide; Rats; Rats, Inbred Strains; Tryptophan

1988
Dihydrofolate reductase. 1H resonance assignments and coenzyme-induced conformational changes.
    Journal of molecular biology, 1986, Mar-05, Volume: 188, Issue:1

    Topics: Amino Acid Sequence; Histidine; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Models, Molecular; NADP; Phenylalanine; Protein Conformation; Protons; Tetrahydrofolate Dehydrogenase; Tryptophan; Tyrosine

1986
Characteristics of the active oxygen in covalent binding of the pesticide methoxychlor to hepatic microsomal proteins.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Benzoates; Benzoic Acid; beta Carotene; Butanols; Carotenoids; Catalase; Deferoxamine; Edetic Acid; Ethanol; Histidine; Hydrogen Peroxide; Mannitol; Methoxychlor; Microsomes, Liver; NADP; Oxygen; Pentetic Acid; Proteins; Salicylates; Superoxide Dismutase; Superoxides; tert-Butyl Alcohol; Tryptophan; Zinc

1986
Increased urinary excretion of tryptophan metabolites in rats exposed to nitrogen dioxide.
    Bulletin of environmental contamination and toxicology, 1988, Volume: 40, Issue:1

    Topics: Animals; Body Weight; Kynurenic Acid; Liver; Male; NAD; NADP; Nitrogen Dioxide; Pyridoxal Phosphate; Rats; Rats, Inbred F344; Tryptophan; Xanthurenates

1988
[Localization of tryptophan residues in NADPH-adrenodoxin reductase with respect to the NADPH-binding center].
    Biokhimiia (Moscow, Russia), 1987, Volume: 52, Issue:7

    Topics: Adrenal Cortex; Animals; Binding Sites; Bromosuccinimide; Ferredoxin-NADP Reductase; Mitochondria; NADH, NADPH Oxidoreductases; NADP; Spectrometry, Fluorescence; Tryptophan

1987
[The role of tryptophan residues of NADPH-adrenodoxin reductase in the formation of complex with adrenodoxin].
    Biokhimiia (Moscow, Russia), 1987, Volume: 52, Issue:8

    Topics: Adrenal Cortex; Adrenodoxin; Animals; Bromosuccinimide; Catalysis; Cattle; Electron Transport; Ferredoxin-NADP Reductase; Kinetics; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Tryptophan

1987
Pyrrolooxygenases: isolation, properties, and products formed.
    Biochimica et biophysica acta, 1972, Sep-19, Volume: 284, Issue:1

    Topics: Ammonium Sulfate; Animals; Arylformamidase; Chemical Phenomena; Chemical Precipitation; Chemistry; Chloroplasts; Chromatography, DEAE-Cellulose; Chromatography, Gel; Drug Stability; Hot Temperature; Indoles; Light; Liver; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Oxygen; Plants; Radiation Effects; Rats; Skatole; Structure-Activity Relationship; Sulfites; Tryptophan

1972
Effects of oxidation of tryptophan residues in thioredoxin from Escherichia coli by N-bromosuccinimide.
    The Journal of biological chemistry, 1973, Jun-10, Volume: 248, Issue:11

    Topics: Alcohol Oxidoreductases; Amino Acids; Animals; Bacterial Proteins; Chemical Phenomena; Chemistry; Chromatography, Gel; Cross Reactions; Electron Transport; Escherichia coli; Immunodiffusion; Indoles; NADP; Oxidation-Reduction; Oxidoreductases; Precipitin Tests; Pyrrolidinones; Rabbits; Ribonucleotides; Spectrometry, Fluorescence; Structure-Activity Relationship; Succinimides; Tryptophan

1973
The effects of chronic phenobarbitone administration and subsequent withdrawal on the activity of rat liver tryptohan pyrrolase and their resemblance to those of ethanol.
    The Biochemical journal, 1973, Volume: 135, Issue:3

    Topics: Animals; Depression, Chemical; Ethanol; Humans; Hydrocortisone; Injections, Intraperitoneal; Kynurenine; Liver; NAD; NADP; Phenobarbital; Rats; Sodium Chloride; Sodium Salicylate; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Oxygenase

1973
Effect of acetoacetate on liver and blood pyridine nucleotides in rats.
    Journal of nutritional science and vitaminology, 1973, Volume: 19, Issue:4

    Topics: Acetoacetates; Administration, Oral; Animals; Deficiency Diseases; Depression, Chemical; Liver; Male; NAD; NADP; Nicotinic Acids; Rats; Tryptophan

1973
Implication of a tryptophyl residue in the active site of dihydrofolate reductase.
    Biochemistry, 1974, Apr-23, Volume: 13, Issue:9

    Topics: Amino Acids; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Dialysis; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Folic Acid Antagonists; Lacticaseibacillus casei; Methotrexate; NADP; Oxidation-Reduction; Protein Denaturation; Spectrophotometry, Ultraviolet; Succinimides; Tetrahydrofolate Dehydrogenase; Tryptophan; Urea

1974
[Studies on tryptophan metabolism in oligophrenic children. 2. Vitamin-dependent enzyme patterns (B1, B2, B6) and excretion of the tryptophan metabolites kynurenin, xanthurenic acid, trigonellinamide, and N-methylpyridone].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1974, Volume: 26, Issue:6

    Topics: Child; Female; Humans; Hydrolases; Intellectual Disability; Kynurenine; Liver; Male; NADP; Pyridoxine; Riboflavin; Thiamine; Tryptophan; Xanthurenates

1974
The relation between urinary excretion of tryptophan and niacin metabolites and pyridine nucleotides in the liver in rats fed a tryptophan-deficient diet.
    Journal of nutritional science and vitaminology, 1974, Volume: 20, Issue:4

    Topics: Adenine Nucleotides; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Deficiency Diseases; Female; Liver; NAD; NADP; Niacinamide; Nicotinic Acids; Nucleotides; Organ Size; Pyridones; Rats; Tryptophan

1974
Enzymic demethylation of a carcinogenic tryptophan metabolite, 8-methoxykynurenic acid.
    Biochemical pharmacology, 1974, Jul-01, Volume: 23, Issue:13

    Topics: Animals; Carcinogens; Kidney; Kinetics; Kynurenic Acid; Liver; NAD; NADP; Organ Specificity; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Rats; Tryptophan

1974
Effect of endotoxin on metabolic regulation in mice.
    Annales immunologiae Hungaricae, 1973, Volume: 17

    Topics: Animals; Carbon Radioisotopes; Cortisone; Cyproheptadine; Drug Antagonism; Endotoxins; Energy Metabolism; Enzyme Induction; Injections, Intraperitoneal; Injections, Intravenous; Kynurenine; Lethal Dose 50; Leucine; Liver; Mice; NAD; NADP; Orotic Acid; Protein Biosynthesis; RNA; Tryptophan; Tryptophan Oxygenase; Tyrosine Transaminase

1973
Pyridine nucleotides in the thyroid gland. II. Effect of nicotinamide, nicotinic acid and L-tryptophan administration.
    Endocrinology, 1968, Volume: 82, Issue:2

    Topics: Animals; Kinetics; Male; NAD; NADP; Niacin; Niacinamide; Oxidation-Reduction; Rats; Thyroid Gland; Tryptophan

1968
An assay procedure for nicotinamide-adenine dinucleotides in rat liver and other tissues.
    Archives internationales de physiologie et de biochimie, 1964, Volume: 72, Issue:3

    Topics: Alcohol Oxidoreductases; Animals; Buffers; Chemistry Techniques, Analytical; Edetic Acid; Ethanol; Glucosephosphate Dehydrogenase; In Vitro Techniques; Indicators and Reagents; Liver; NAD; NADP; Niacinamide; Phenazines; Phenols; Phosphates; Rats; Spectrophotometry; Subcellular Fractions; Tryptophan

1964
Inhibition of liver phenylalanine and tryptophan hydroxylating enzyme systems in vitro and in vivo.
    Acta pharmacologica et toxicologica, 1966, Volume: 24, Issue:1

    Topics: Aminopterin; Animals; Brain Chemistry; Coumarins; Enzyme Induction; Enzymes; Flavonoids; In Vitro Techniques; Liver; Liver Extracts; Methyldopa; Mice; Mixed Function Oxygenases; NAD; NADP; Phenylacetates; Phenylalanine; Rats; Serotonin; Tryptophan

1966
Feedback control of rat liver tryptophan pyrrolase. I. End product inhibition of trytophan pyrrolase activity.
    The Journal of biological chemistry, 1967, Mar-25, Volume: 242, Issue:6

    Topics: Animals; Buffers; Chromatography; Electrophoresis; Enzymes; Hot Temperature; Kinetics; Liver; Molecular Weight; NAD; NADP; Niacinamide; Nicotinic Acids; Nucleotides; Oxidoreductases; Rats; Tryptophan; Ultracentrifugation

1967
Indolelactate dehydrogenase from Clostridium sporogenes.
    Canadian journal of microbiology, 1968, Volume: 14, Issue:4

    Topics: Clostridium; Indoles; Kinetics; L-Lactate Dehydrogenase; NAD; NADP; Tryptophan

1968
[Oxidases and oxygenases in higher plants, I. On the occurrence of indolyl-(3)-acetaldehyde oxime and its formation from L-tryptophan].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1968, Volume: 349, Issue:4

    Topics: Acetaldehyde; Carbon Isotopes; NADP; Oxidoreductases; Oximes; Oxygenases; Plants; Tryptophan

1968
Regulation of NAD biosynthesis via the pyridine nucleotide cycle.
    The Journal of vitaminology, 1968, Mar-05, Volume: 14

    Topics: Adenosine Triphosphate; Animals; Bacillus; Carbon Isotopes; Escherichia coli; Hypophysectomy; In Vitro Techniques; Liver; NAD; NADP; Niacinamide; Nicotinic Acids; Nucleotides; Pyridines; Pyrophosphatases; Rats; Transferases; Tryptophan; Tryptophan Oxygenase

1968
Prevention and remission by adrenocortical steriods of nicotinamide deficiency disease. II. A study of the mechanism.
    The Journal of biological chemistry, 1968, Aug-25, Volume: 243, Issue:16

    Topics: Adrenal Cortex Hormones; Animals; Corticosterone; Deficiency Diseases; NAD; NADP; Niacinamide; Nucleotides; Pyridines; Rats; Tryptophan

1968
The loss of antigen(or hapten)-binding activity of Fab fragments of antibodies after irradiation by monochromatic ultraviolet light at 289 nm.
    Biochimica et biophysica acta, 1969, Volume: 175, Issue:2

    Topics: Animals; Antibodies; Antigen-Antibody Reactions; Binding Sites; Dinitrophenols; Fluorometry; Immune Sera; NADP; Rabbits; Radiation Effects; Spectrum Analysis; Tryptophan; Ultraviolet Rays

1969
Effect of N-bromosuccinimide on dihydrofolate reductase.
    Biochemistry, 1969, Volume: 8, Issue:6

    Topics: Animals; Benzoates; Binding Sites; Bromine; Chemical Phenomena; Chemistry; Chickens; Hydrogen-Ion Concentration; Imides; Liver; Mercury; Molecular Weight; NADP; Pyrrolidinones; Spectrophotometry; Succinates; Sulfhydryl Compounds; Tetrahydrofolate Dehydrogenase; Tryptophan

1969
Effect in man of the addition of tryptophan oniacin to the diet on the excretion of their metabolites.
    The Journal of nutrition, 1969, Volume: 99, Issue:3

    Topics: Creatinine; Diet; Female; Humans; Kynurenic Acid; NAD; NADP; Niacinamide; Nicotinic Acids; Nitrogen; Pyridones; Tryptophan; Urea; Xanthurenates

1969
Agroclavine hydroxylase of Claviceps purpurea.
    Biochimica et biophysica acta, 1971, Volume: 230, Issue:3

    Topics: Aminopterin; Ascomycota; Carbon Isotopes; Chromatography, Thin Layer; Cyanides; Edetic Acid; Ergot Alkaloids; Hydrogen-Ion Concentration; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygenases; Spectrophotometry; Tritium; Tryptophan

1971
Effects of amino acid derivatives and drugs on the metabolism of tryptophan.
    The American journal of clinical nutrition, 1971, Volume: 24, Issue:7

    Topics: Adrenal Glands; Adrenalectomy; Animals; Brain; Carbon Dioxide; Carbon Isotopes; Chromatography, Paper; Deficiency Diseases; Depression, Chemical; Hydrocortisone; Hydroxyindoleacetic Acid; Liver; Metabolism; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; NAD; NADP; Oxidation-Reduction; Protein Biosynthesis; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase; Yohimbine

1971
Circular dichroic titration of dihydrofolate reductase with TPNH.
    Biochemical and biophysical research communications, 1971, Nov-05, Volume: 45, Issue:3

    Topics: Chemical Phenomena; Chemistry; Circular Dichroism; NADP; Protein Binding; Streptococcus; Tetrahydrofolate Dehydrogenase; Tryptophan

1971
Tryptophan availability as a control of hepatic pyridine nucleotide concentration in mice.
    Biochimica et biophysica acta, 1971, Nov-12, Volume: 252, Issue:2

    Topics: Adrenalectomy; Allopurinol; Animals; Depression, Chemical; Hydrocortisone; Kinetics; Liver; Male; Mice; NAD; NADP; Stimulation, Chemical; Tryptophan; Tryptophan Oxygenase

1971
Conversion of agroclavine by mammalian cytochrome P-450.
    Biochimica et biophysica acta, 1971, Nov-12, Volume: 252, Issue:2

    Topics: Adrenal Glands; Animals; Benzopyrenes; Biotransformation; Carbon Isotopes; Chromatography, Thin Layer; Cytochromes; Ergot Alkaloids; Guinea Pigs; Isotope Labeling; Male; Microsomes; Microsomes, Liver; NADP; Phenobarbital; Protein Binding; Rabbits; Rats; Species Specificity; Spectrophotometry; Tryptophan

1971
[Tryptophan metabolism of streptomycetes. 3. Tryptophan degradation in cell free extracts of Streptomyces cremeus].
    Zeitschrift fur allgemeine Mikrobiologie, 1971, Volume: 11, Issue:5

    Topics: Ammonium Sulfate; Coenzymes; Enzyme Induction; Methylene Blue; NAD; NADP; ortho-Aminobenzoates; Streptomyces; Toluidines; Tryptophan

1971
[Hydroxylation of phenylalanine by Hydrogenomonas eutropha H 16].
    Archiv fur Mikrobiologie, 1972, Volume: 83, Issue:1

    Topics: Cell-Free System; Chromatography, Gel; Enzyme Induction; Mixed Function Oxygenases; NAD; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pseudomonas; Tryptophan; Tyrosine

1972
Partial purification and characterization of tryptophan hydroxylase from rabbit hindbrain.
    The Journal of biological chemistry, 1972, Jul-10, Volume: 247, Issue:13

    Topics: Ammonium Sulfate; Animals; Brain; Calcium Phosphates; Carbon Isotopes; Catalase; Chromatography, Thin Layer; Colorimetry; Decarboxylation; Hydrogen Peroxide; Iron; Kinetics; Mixed Function Oxygenases; NADP; Oxidoreductases; Oxygen; Pteridines; Pterins; Rabbits; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Tryptophan

1972
Pyrrolooxygenase: its action on tryptophan-containing enzymes and peptides.
    Biochimica et biophysica acta, 1972, Sep-19, Volume: 284, Issue:1

    Topics: Animals; Bromine; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Chymotrypsin; Indoles; Liver; Microsomes, Liver; Muramidase; NADP; Oxidation-Reduction; Oxidoreductases; Papain; Pepsin A; Peptides; Plants; Rats; Succinimides; Sulfites; Trypsin Inhibitors; Tryptophan

1972
The binding of -ketoglutarate in a binary complex and in a ternary complex with NADP + by L-glutamate dehydrogenase.
    Biochimica et biophysica acta, 1972, Nov-10, Volume: 289, Issue:1

    Topics: Animals; Binding Sites; Catalysis; Cattle; Chemical Phenomena; Chemistry; Glutamate Dehydrogenase; Glutamates; Ketoglutaric Acids; Kinetics; Liver; Mathematics; Molecular Weight; NADP; Niacinamide; Oxidation-Reduction; Protein Binding; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tryptophan

1972
Regulation of pyridine nucleotide levels and ratios in Neurospora crassa.
    The Journal of biological chemistry, 1972, Oct-10, Volume: 247, Issue:19

    Topics: Culture Media; Genetics, Microbial; Glucosephosphate Dehydrogenase; Kynurenine; Mixed Function Oxygenases; Mutation; NAD; NADP; Neurospora; Neurospora crassa; Nicotinic Acids; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Tryptophan

1972
Effects of excess leucine on growth and tryptophan and niacin metabolism in rats.
    Journal of nutritional science and vitaminology, 1980, Volume: 26, Issue:2

    Topics: Animals; Body Weight; Diet; Erythrocytes; Female; Hydroxyindoleacetic Acid; Isoleucine; Leucine; NAD; NADP; Nicotinic Acids; Organ Size; Pellagra; Quinolinic Acids; Rats; Time Factors; Tryptophan; Valine; Vitamin B 6 Deficiency

1980
Effect of L-tryptophan and L-leucine on biosynthesis of niacin-related compounds in Saccharomyces carlsbergensis.
    Journal of nutritional science and vitaminology, 1982, Volume: 28, Issue:3

    Topics: Culture Media; Leucine; NAD; NADP; Niacin; Niacinamide; Nicotinamidase; Pentosyltransferases; Saccharomyces; Tryptophan

1982
The effects of a dietary excess of leucine on the synthesis of nicotinamide nucleotides in the rat.
    The British journal of nutrition, 1983, Volume: 49, Issue:3

    Topics: Animals; Diet; Enzyme Activation; Hydrolases; Kynurenine; Leucine; Liver; Male; NADP; Niacin; Niacinamide; Pellagra; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase

1983
Inhibition of tryptophan metabolism by oestrogens in the rat: a factor in the aetiology of pellagra.
    The British journal of nutrition, 1984, Volume: 51, Issue:2

    Topics: Animals; Castration; Estrone; Female; Liver; NAD; NADP; Niacinamide; Pellagra; Rats; Rats, Inbred Strains; Tryptophan

1984
In vivo conversion of tryptophan to nicotinic acid in rats studied by simultaneous incorporation of [3H]-tryptophan and [14C]-nicotinic acid into liver NAD and NADP.
    Annals of nutrition & metabolism, 1983, Volume: 27, Issue:1

    Topics: Animals; Dietary Proteins; Liver; NAD; NADP; Niacin; Rats; Rats, Inbred Strains; Tryptophan; Weaning

1983
Kynurenine hydroxylase mutants of the nematode Caenorhabditis elegans.
    Molecular & general genetics : MGG, 1980, Volume: 179, Issue:1

    Topics: Animals; Caenorhabditis; Chromosome Mapping; Genetic Complementation Test; Kynurenine 3-Monooxygenase; Mixed Function Oxygenases; Mutation; NAD; NADP; Tryptophan

1980
Effects of niacin deficiency on pyridine nucleotide levels and enzyme activities in various organs of young growing quail.
    The Journal of nutrition, 1982, Volume: 112, Issue:5

    Topics: Animals; Body Weight; Coturnix; Dose-Response Relationship, Drug; Liver; Muscles; NAD; NADP; Niacin; Nicotinic Acids; Quail; Tryptophan

1982
Nuclear magnetic resonance study of interaction of ligands with streptococcus faecium dihydrofolate reductase labeled with [gamma-13C]tryptophan.
    Biochemistry, 1982, Aug-31, Volume: 21, Issue:18

    Topics: Adenosine Diphosphate Ribose; Carbon Isotopes; Folic Acid; Magnetic Resonance Spectroscopy; Methotrexate; NADP; Pteroylpolyglutamic Acids; Pyrimidines; Spin Labels; Streptococcus; Tetrahydrofolate Dehydrogenase; Tryptophan

1982
Possible involvement of the enhanced tryptophan pyrrolase activity in the corticosterone- and starvation-induced increases in concentrations of nicotinamide-adenine dinucleotides (phosphates) in rat liver.
    The Biochemical journal, 1981, Apr-15, Volume: 196, Issue:1

    Topics: Allopurinol; Animals; Corticosterone; Dactinomycin; Glucose; Liver; Male; NAD; NADP; Propranolol; Rats; Starvation; Stimulation, Chemical; Tryptophan; Tryptophan Oxygenase

1981
Contributions of tryptophan 24 and glutamate 30 to binding long-lived water molecules in the ternary complex of human dihydrofolate reductase with methotrexate and NADPH studied by site-directed mutagenesis and nuclear magnetic resonance spectroscopy.
    Journal of molecular biology, 1995, Mar-24, Volume: 247, Issue:2

    Topics: Amino Acid Sequence; Glutamic Acid; Humans; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Methotrexate; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Recombinant Proteins; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tryptophan; Water

1995
Mechanism of aldose reductase inhibition: binding of NADP+/NADPH and alrestatin-like inhibitors.
    Biochemistry, 1994, Jun-14, Volume: 33, Issue:23

    Topics: Aldehyde Reductase; Base Sequence; Binding Sites; Coenzymes; Isoquinolines; Molecular Sequence Data; Mutation; NADP; Oligodeoxyribonucleotides; Protein Binding; Recombinant Proteins; Spectrometry, Fluorescence; Tryptophan

1994
NADPH-initiated cytochrome P450-mediated free metal ion-independent oxidative damage of microsomal proteins. Exclusive prevention by ascorbic acid.
    The Journal of biological chemistry, 1994, May-06, Volume: 269, Issue:18

    Topics: Adenosine Diphosphate; Animals; Ascorbic Acid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Guinea Pigs; Hydrolysis; Iron; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Proteins; Tryptophan; Tyrosine

1994
19F NMR spectroscopy of [6-19F]tryptophan-labeled Escherichia coli dihydrofolate reductase: equilibrium folding and ligand binding studies.
    Biochemistry, 1994, May-10, Volume: 33, Issue:18

    Topics: Base Sequence; Binding Sites; DNA Primers; Escherichia coli; Ligands; Magnetic Resonance Spectroscopy; Methotrexate; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Protein Conformation; Protein Folding; Tetrahydrofolate Dehydrogenase; Tryptophan; Urea

1994
Quantitative efficacy of niacin sources for chicks: nicotinic acid, nicotinamide, NAD and tryptophan.
    The Journal of nutrition, 1993, Volume: 123, Issue:12

    Topics: Analysis of Variance; Animal Feed; Animals; Biological Assay; Chickens; Dose-Response Relationship, Drug; Eating; Liver; Male; Muscles; NAD; NADP; Niacin; Niacinamide; Regression Analysis; Tryptophan; Weight Gain

1993
Purification, kinetic characterization and involvement of tryptophan residue at the NADPH binding site of xylose reductase from Neurospora crassa.
    Biochimica et biophysica acta, 1996, Apr-16, Volume: 1293, Issue:2

    Topics: Aldehyde Reductase; Anilino Naphthalenesulfonates; Binding Sites; Bromosuccinimide; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Kinetics; Molecular Weight; NADP; Neurospora crassa; Protein Conformation; Spectrometry, Fluorescence; Tryptophan

1996
Fluorescence-energy transfer in human estradiol 17 beta-dehydrogenase-NADPH complex and studies on the coenzyme binding,.
    European journal of biochemistry, 1996, Jan-15, Volume: 235, Issue:1-2

    Topics: Binding Sites; Cold Temperature; Energy Transfer; Estradiol Dehydrogenases; Humans; In Vitro Techniques; Kinetics; Molecular Structure; NADP; Spectrometry, Fluorescence; Tryptophan

1996
Characterization of the substrate binding site in rat liver 3alpha-hydroxysteroid/dihydrodiol dehydrogenase. The roles of tryptophans in ligand binding and protein fluorescence.
    The Journal of biological chemistry, 1996, Nov-22, Volume: 271, Issue:47

    Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Alcohol Oxidoreductases; Animals; Enzyme Inhibitors; Fluorescence; Kinetics; Ligands; Liver; Mutagenesis, Site-Directed; NADP; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Rats; Substrate Specificity; Testosterone; Tryptophan

1996
Refolding of [6-19F]tryptophan-labeled Escherichia coli dihydrofolate reductase in the presence of ligand: a stopped-flow NMR spectroscopy study.
    Biochemistry, 1998, Jan-06, Volume: 37, Issue:1

    Topics: Circular Dichroism; Escherichia coli; Fluorine; Folic Acid; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; NADP; Protein Folding; Spectrometry, Fluorescence; Tetrahydrofolate Dehydrogenase; Tryptophan

1998
Study of the photochemical and phototoxic properties of lonidamine [1-(2,4-dichlorobenzyl)-1H-indazol-3-carboxylic acid].
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 41, Issue:1-2

    Topics: Animals; Female; Indazoles; Mice; Molecular Structure; NADP; Radiation-Sensitizing Agents; Tryptophan; Tumor Cells, Cultured; Ultraviolet Rays

1997
Resonant energy transfer from proteins to pyridine nucleotides in mitochondria.
    Biochemistry. Biokhimiia, 1998, Volume: 63, Issue:9

    Topics: Animals; Energy Transfer; In Vitro Techniques; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Proteins; Rats; Spectrometry, Fluorescence; Tryptophan

1998
The arginine 276 anchor for NADP(H) dictates fluorescence kinetic transients in 3 alpha-hydroxysteroid dehydrogenase, a representative aldo-keto reductase.
    Biochemistry, 1999, Jun-15, Volume: 38, Issue:24

    Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Arginine; Binding Sites; Kinetics; Liver; Methionine; Mutagenesis, Site-Directed; NAD; NADP; Oxidation-Reduction; Rats; Recombinant Proteins; Spectrometry, Fluorescence; Static Electricity; Time Factors; Tryptophan

1999
Tryptophan 409 controls the activity of neuronal nitric-oxide synthase by regulating nitric oxide feedback inhibition.
    The Journal of biological chemistry, 1999, Sep-17, Volume: 274, Issue:38

    Topics: Escherichia coli; Feedback; Hydrogen Peroxide; Kinetics; Models, Chemical; Models, Molecular; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Point Mutation; Structure-Activity Relationship; Tryptophan

1999
Evidence for the stabilization of NADPH relative to NADP(+) on the dIII components of proton-translocating transhydrogenases from Homo sapiens and from Rhodospirillum rubrum by measurement of tryptophan fluorescence.
    Biochimica et biophysica acta, 1999, Oct-06, Volume: 1413, Issue:2

    Topics: Animals; Binding Sites; Fluorescence; Hominidae; Humans; Kinetics; NAD; NADP; NADP Transhydrogenases; Oxidation-Reduction; Rhodospirillum rubrum; Tryptophan

1999
Effects of peroxisome-proliferators on the TRP-NAD pathway.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Animals; Carboxy-Lyases; Cells, Cultured; Clofibrate; Female; Liver; Male; NAD; NADP; Niacin; Oxidation-Reduction; Pentosyltransferases; Peroxisome Proliferators; Peroxisomes; Phenothiazines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tryptophan

1999
Effects of single-tryptophan mutations on R67 dihydrofolate reductase.
    Biochemistry, 2000, Apr-04, Volume: 39, Issue:13

    Topics: Binding Sites; Chromatography, Gel; Circular Dichroism; Energy Transfer; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; NADP; Phenylalanine; Protein Folding; Quantum Theory; R Factors; Spectrometry, Fluorescence; Tetrahydrofolate Dehydrogenase; Tryptophan

2000
Aromatic residues and neighboring Arg414 in the (6R)-5,6,7, 8-tetrahydro-L-biopterin binding site of full-length neuronal nitric-oxide synthase are crucial in catalysis and heme reduction with NADPH.
    The Journal of biological chemistry, 2000, Aug-25, Volume: 275, Issue:34

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Binding Sites; Biopterins; Catalysis; Dimerization; Drosophila; Glutamine; Heme; Humans; Hydrogen Bonding; Leucine; Mice; Models, Molecular; Molecular Sequence Data; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Phenylalanine; Rats; Spectrophotometry, Atomic; Structure-Activity Relationship; Tryptophan

2000
Systematic circular permutation of an entire protein reveals essential folding elements.
    Nature structural biology, 2000, Volume: 7, Issue:7

    Topics: Binding Sites; Circular Dichroism; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; NADP; Peptide Fragments; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tetrahydrofolate Dehydrogenase; Thermodynamics; Titrimetry; Tryptophan; Urea

2000
Functional interactions in cytochrome P450BM3. Evidence that NADP(H) binding controls redox potentials of the flavin cofactors.
    Biochemistry, 2000, Oct-17, Volume: 39, Issue:41

    Topics: Animals; Bacterial Proteins; Binding, Competitive; Cytochrome P-450 Enzyme System; Electron Transport; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Flavoproteins; Mixed Function Oxygenases; Mutagenesis, Site-Directed; NAD; NADP; NADP Transhydrogenases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Phosphorus Radioisotopes; Protein Binding; Protein Structure, Tertiary; Protons; Rats; Spectrometry, Fluorescence; Tryptophan

2000
Trp-676 facilitates nicotinamide coenzyme exchange in the reductive half-reaction of human cytochrome P450 reductase: properties of the soluble W676H and W676A mutant reductases.
    Biochemistry, 2000, Dec-26, Volume: 39, Issue:51

    Topics: Alanine; Binding Sites; Catalysis; Cytochrome c Group; Enzyme Activation; Flavin-Adenine Dinucleotide; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Structure, Tertiary; Recombinant Proteins; Solubility; Spectrometry, Fluorescence; Thermodynamics; Tryptophan

2000
A change in ionization of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase regulates both hydride transfer and nucleotide release.
    European journal of biochemistry, 2001, Volume: 268, Issue:5

    Topics: Amino Acid Substitution; Binding Sites; Catalysis; Fluorescence; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Mutation; NADP; NADP Transhydrogenases; Nucleotides; Protein Conformation; Protein Subunits; Protons; Rhodospirillum rubrum; Spectrometry, Fluorescence; Tryptophan

2001
NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer.
    The Journal of biological chemistry, 2001, Aug-03, Volume: 276, Issue:31

    Topics: Amino Acid Substitution; Animals; Catalysis; Crystallography, X-Ray; Electron Transport; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Humans; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; NADP; NADPH-Ferrihemoprotein Reductase; Niacinamide; Protein Conformation; Rats; Recombinant Proteins; Serine; Spectrophotometry; Tryptophan

2001
Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats.
    Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:6

    Topics: Animals; Antitubercular Agents; Diet; Eating; Liver; Male; NAD; NADP; Niacin; Pyrazinamide; Quinolinic Acid; Rats; Rats, Wistar; Serotonin; Tryptophan; Weight Gain

2001
Elevation of blood NAD level after moderate exercise in young women and mice.
    Journal of nutritional science and vitaminology, 2001, Volume: 47, Issue:2

    Topics: Adult; Animals; Exercise; Female; Humans; Male; Mice; Mice, Inbred ICR; NAD; NADP; Physical Exertion; Tryptophan

2001
Anabaena sp. PCC 7119 flavodoxin as electron carrier from photosystem I to ferredoxin-NADP+ reductase. Role of Trp(57) and Tyr(94).
    The Journal of biological chemistry, 2002, Jun-21, Volume: 277, Issue:25

    Topics: Anabaena; Desulfovibrio vulgaris; Dose-Response Relationship, Drug; Electrons; Ferredoxin-NADP Reductase; Flavodoxin; Kinetics; Microscopy, Fluorescence; Models, Chemical; Mutation; NADP; Photosynthetic Reaction Center Complex Proteins; Protein Binding; Riboflavin; Spectrophotometry; Thermodynamics; Time Factors; Tryptophan; Tyrosine; Ultraviolet Rays

2002
Elucidation of the toxic mechanism of the plasticizers, phthalic acid esters, putative endocrine disrupters: effects of dietary di(2-ethylhexyl)phthalate on the metabolism of tryptophan to niacin in rats.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:4

    Topics: Administration, Oral; Animals; Body Weight; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Energy Intake; Liver; NAD; NADP; Niacin; Organ Size; Rats; Tryptophan

2002
Effects of fatty liver induced by niacin-free diet with orotic acid on the metabolism of tryptophan to niacin in rats.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:6

    Topics: Animals; Diet; Fats; Fatty Liver; Feeding Behavior; Liver; Male; NAD; NADP; Niacin; Organ Size; Orotic Acid; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Vitamin B Deficiency; Weight Gain

2002
Tryptophan phosphorescence spectroscopy reveals that a domain in the NAD(H)-binding component (dI) of transhydrogenase from Rhodospirillum rubrum has an extremely rigid and conformationally homogeneous protein core.
    The Journal of biological chemistry, 2003, Nov-28, Volume: 278, Issue:48

    Topics: Acrylamide; Dimerization; Escherichia coli; Glycerol; Kinetics; Luminescent Measurements; Models, Molecular; NAD; NADP; NADP Transhydrogenases; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protons; Rhodospirillum rubrum; Spectrometry, Fluorescence; Spectrophotometry; Temperature; Time Factors; Tryptophan

2003
INITIATION OF ENZYME FORMATION BY BIRTH.
    Annals of the New York Academy of Sciences, 1963, Dec-30, Volume: 111

    Topics: Animals; Animals, Newborn; Glucose-6-Phosphatase; Guinea Pigs; Liver; NADP; Research; Tryptophan

1963
HARTNUP DISEASE IN TWO SIBLINGS. CLINICAL OBSERVATIONS AND BIOCHEMICAL STUDIES.
    Annales paediatriae Fenniae, 1964, Volume: 10

    Topics: Adolescent; Ataxia; Child; Eczema; Genetics, Medical; Hartnup Disease; Humans; NAD; NADP; Niacin; Nicotinic Acids; Pellagra; Protein Deficiency; Renal Aminoacidurias; Siblings; Tryptophan

1964
NICOTINAMIDE ADENINE DINUCLEOTIDE LEVELS IN RAT BRAIN.
    Canadian journal of biochemistry, 1964, Volume: 42

    Topics: Brain; Dietary Fats; Metabolism; NAD; NADP; Niacin; Niacinamide; Nicotinic Acids; Pharmacology; Protein Deficiency; Rats; Research; Reserpine; Tryptophan

1964
INFLUENCE OF GELATIN ON GROWTH AND LIVER PYRIDINE NUCLEOTIDE CONCENTRATION OF THE RAT.
    The Journal of nutrition, 1964, Volume: 83, Issue:2

    Topics: Amino Acids; Caseins; Diet; Gelatin; Glycine; Growth; Liver; NAD; NADP; Niacin; Nicotinic Acids; Nucleotides; Rats; Research; Tryptophan

1964
ENZYMATIC FORMATION OF CATECHOL FROM ANTHRANILIC ACID.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Benzene; Benzoates; Carbon Isotopes; Catechols; Glycols; Kynurenic Acid; Levulinic Acids; Metabolism; Mixed Function Oxygenases; NAD; NADP; ortho-Aminobenzoates; Oxidoreductases; Pseudomonas; Research; Salicylic Acid; Tryptophan

1964
PITUITARY INFLUENCE OF PYRIDINE NUCLEOTIDE METABOLISM OF RAT LIVER.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Adrenal Glands; Brain Chemistry; Fluorometry; Hypophysectomy; Intestines; Kidney; Liver; Lung; Metabolism; Muscles; Myocardium; NAD; NADP; Niacin; Niacinamide; Pharmacology; Pituitary Gland; Rats; Research; Spectrophotometry; Spleen; Tryptophan

1964
Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats.
    Bioscience, biotechnology, and biochemistry, 2004, Volume: 68, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Eating; Liver; Male; NAD; NADP; Niacinamide; Nicotinic Acids; Predictive Value of Tests; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Weaning; Weight Gain

2004
The catalytic and kinetic mechanisms of NADPH-dependent alkenal/one oxidoreductase.
    The Journal of biological chemistry, 2004, Apr-23, Volume: 279, Issue:17

    Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Antioxidants; Carbon; Catalysis; Deuterium; Hydrogen; Hydrogen-Ion Concentration; Ketones; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; NADH, NADPH Oxidoreductases; NADP; Oxygen; Phylogeny; Progesterone; Protein Binding; Rats; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry, Atomic; Stereoisomerism; Tryptophan; Zinc

2004
Switching pyridine nucleotide specificity in P450 BM3: mechanistic analysis of the W1046H and W1046A enzymes.
    The Journal of biological chemistry, 2005, May-06, Volume: 280, Issue:18

    Topics: Alanine; Amino Acid Substitution; Animals; Bacillus megaterium; Bacterial Proteins; Cytochrome P-450 Enzyme System; Flavin-Adenine Dinucleotide; Histidine; Kinetics; Mixed Function Oxygenases; Mutation; NADP; NADPH-Ferrihemoprotein Reductase; Potentiometry; Protein Structure, Tertiary; Pyridines; Rats; Spectrophotometry; Substrate Specificity; Thermodynamics; Tryptophan

2005
Structural basis of eukaryotic nitrate reduction: crystal structures of the nitrate reductase active site.
    The Plant cell, 2005, Volume: 17, Issue:4

    Topics: Animals; Arginine; Binding Sites; Body Water; Chickens; Crystallography, X-Ray; Electron Transport Chain Complex Proteins; Eukaryotic Cells; Models, Molecular; Molecular Sequence Data; Molybdenum; NADP; Nitrate Reductases; Nitrates; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Pichia; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Tryptophan

2005
A tryptophan that modulates tetrahydrobiopterin-dependent electron transfer in nitric oxide synthase regulates enzyme catalysis by additional mechanisms.
    Biochemistry, 2005, Mar-29, Volume: 44, Issue:12

    Topics: Animals; Arginine; Biopterins; Catalysis; Dimerization; Electron Transport; Enzyme Stability; Ferrous Compounds; Heme; Hydroxylation; Isoenzymes; Kinetics; Mice; Mutagenesis, Site-Directed; NADP; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Oxidation-Reduction; Protein Binding; Rats; Spectrophotometry; Tryptophan

2005
Release of oxidized plastocyanin from photosystem I limits electron transfer between photosystem I and cytochrome b6f complex in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, May-10, Volume: 102, Issue:19

    Topics: Animals; Binding Sites; Chlamydomonas; Cytochrome b6f Complex; Dose-Response Relationship, Drug; Electrons; Glutamic Acid; Glutamine; Kinetics; Mutation; NADP; Oxygen; Phenotype; Photosynthesis; Photosystem I Protein Complex; Plastocyanin; Protein Binding; Serine; Spectrophotometry; Time Factors; Tryptophan

2005
Conversion ratio of tryptophan to niacin in Japanese women fed a purified diet conforming to the Japanese Dietary Reference Intakes.
    Journal of nutritional science and vitaminology, 2004, Volume: 50, Issue:6

    Topics: Adult; Diet; Female; Humans; Japan; Male; NAD; NADP; Niacin; Niacinamide; Nutrition Policy; Sex Characteristics; Tryptophan

2004
Mechanistic investigation of a highly active phosphite dehydrogenase mutant and its application for NADPH regeneration.
    The FEBS journal, 2005, Volume: 272, Issue:15

    Topics: Deuterium; Escherichia coli Proteins; Kinetics; Mutation; NAD; NADH, NADPH Oxidoreductases; NADP; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Structural Homology, Protein; Time Factors; Tryptophan; Xylitol

2005
Organization of protochlorophyllide oxidoreductase in prolamellar bodies isolated from etiolated carotenoid-deficient wheat leaves as revealed by fluorescence probes.
    Biochimica et biophysica acta, 2005, Oct-15, Volume: 1716, Issue:2

    Topics: Anilino Naphthalenesulfonates; Carotenoids; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Light; NADP; Oxidoreductases Acting on CH-CH Group Donors; Plant Leaves; Plastids; Protochlorophyllide; Spectrometry, Fluorescence; Spectrophotometry; Temperature; Time Factors; Triticum; Tryptophan

2005
Crystal structure of mouse succinic semialdehyde reductase AKR7A5: structural basis for substrate specificity.
    Biochemistry, 2006, Feb-14, Volume: 45, Issue:6

    Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Enzyme Inhibitors; Hydrophobic and Hydrophilic Interactions; Hydroxybutyrate Dehydrogenase; Liver; Methionine; Mice; Models, Molecular; Molecular Sequence Data; NADP; Substrate Specificity; Tartrates; Tryptophan

2006
Toxoplasma gondii ferredoxin-NADP+ reductase: Role of ionic interactions in stabilization of native conformation and structural cooperativity.
    Proteins, 2008, Volume: 71, Issue:4

    Topics: Animals; Catalysis; Chromatography, Gel; Circular Dichroism; Enzyme Stability; Ferredoxin-NADP Reductase; Flavin-Adenine Dinucleotide; Guanidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Ions; Models, Biological; Models, Molecular; Molecular Weight; NADP; Protein Binding; Protein Conformation; Protein Denaturation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Static Electricity; Temperature; Toxoplasma; Tryptophan

2008
Comparison of the nicotinamide catabolism among rat strains.
    Bioscience, biotechnology, and biochemistry, 2009, Volume: 73, Issue:2

    Topics: Animals; Body Weight; Eating; Male; NAD; NADP; Niacinamide; Rats; Rats, Inbred Strains; Solubility; Species Specificity; Tryptophan; Vitamins; Water

2009
Nuclear magnetic resonance study of the role of M42 in the solution dynamics of Escherichia coli dihydrofolate reductase.
    Biochemistry, 2010, Mar-02, Volume: 49, Issue:8

    Topics: Escherichia coli Proteins; Methionine; Methotrexate; NADP; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Secondary; Tetrahydrofolate Dehydrogenase; Thermodynamics; Tryptophan

2010
The three-dimensional structure of AKR11B4, a glycerol dehydrogenase from Gluconobacter oxydans, reveals a tryptophan residue as an accelerator of reaction turnover.
    Journal of molecular biology, 2010, Dec-03, Volume: 404, Issue:3

    Topics: Amino Acid Sequence; Amino Acid Substitution; Apraxia, Ideomotor; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Gluconobacter oxydans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Static Electricity; Structural Homology, Protein; Substrate Specificity; Sugar Alcohol Dehydrogenases; Tryptophan

2010
Tryptophan 697 modulates hydride and interflavin electron transfer in human methionine synthase reductase.
    Biochemistry, 2011, Dec-27, Volume: 50, Issue:51

    Topics: Amino Acid Sequence; Amino Acid Substitution; Biocatalysis; Electron Transport; Ferredoxin-NADP Reductase; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Flavoproteins; Humans; Hydrogen; Kinetics; Mutant Proteins; NAD; NADP; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Sequence Alignment; Tryptophan

2011
Crystal structure and fluorescence studies reveal the role of helical dimeric interface of staphylococcal FabG1 in positive cooperativity for NADPH.
    Proteins, 2012, Volume: 80, Issue:4

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Bacterial Proteins; Cloning, Molecular; Crystallization; DNA, Bacterial; Escherichia coli; Fluorescence; NADP; Protein Binding; Protein Interaction Mapping; Protein Multimerization; Protein Structure, Secondary; Spectrometry, Fluorescence; Staphylococcus aureus; Tryptophan

2012
Non-destructive evaluation of ATP content and plate count on pork meat surface by fluorescence spectroscopy.
    Meat science, 2013, Volume: 93, Issue:3

    Topics: Adenosine Triphosphate; Animals; Bacteria; Colony Count, Microbial; Food Microbiology; Food Storage; Least-Squares Analysis; Meat; NADP; Reproducibility of Results; Spectrometry, Fluorescence; Swine; Temperature; Tryptophan

2013
Aromatic substitution of the FAD-shielding tryptophan reveals its differential role in regulating electron flux in methionine synthase reductase and cytochrome P450 reductase.
    The FEBS journal, 2013, Volume: 280, Issue:6

    Topics: Amino Acid Substitution; Amino Acids, Aromatic; Catalysis; Cytochrome c Group; Dinitrocresols; Electron Transport; Escherichia coli; Ferredoxin-NADP Reductase; Flavin-Adenine Dinucleotide; Kinetics; Mutagenesis, Site-Directed; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Plasmids; Protein Structure, Tertiary; Recombinant Proteins; Thermodynamics; Titrimetry; Tryptophan

2013
Tryptophan-47 in the active site of Methylophaga sp. strain SK1 flavin-monooxygenase is important for hydride transfer.
    Archives of biochemistry and biophysics, 2013, Apr-01, Volume: 532, Issue:1

    Topics: Amino Acid Sequence; Catalytic Domain; Flavin-Adenine Dinucleotide; Flavins; Mixed Function Oxygenases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Piscirickettsiaceae; Protein Stability; Sequence Alignment; Tryptophan

2013
Biochemical characterization of an L-tryptophan dehydrogenase from the photoautotrophic cyanobacterium Nostoc punctiforme.
    Enzyme and microbial technology, 2014, Jun-10, Volume: 60

    Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Bacterial Proteins; Enzyme Stability; Genes, Bacterial; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Weight; NAD; NADP; Nostoc; Phylogeny; Recombinant Proteins; Sequence Homology, Amino Acid; Stereoisomerism; Substrate Specificity; Temperature; Tryptophan

2014
NADP⁺ binding effects tryptophan accessibility, folding and stability of recombinant B. malayi G6PD.
    International journal of biological macromolecules, 2016, Volume: 85

    Topics: Animals; Brugia malayi; Glucosephosphate Dehydrogenase; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; NADP; Protein Binding; Protein Folding; Protein Stability; Protein Unfolding; Recombinant Proteins; Spectrum Analysis; Tryptophan

2016
Role of active site loop in coenzyme binding and flavin reduction in cytochrome P450 reductase.
    Archives of biochemistry and biophysics, 2016, 09-15, Volume: 606

    Topics: Alanine; Arabidopsis; Arginine; Aspartic Acid; Bacillus megaterium; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Cytochromes c; Flavins; Humans; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Mutation; NADP; NADPH-Ferrihemoprotein Reductase; Protein Binding; Protein Domains; Saccharomyces cerevisiae; Static Electricity; Tryptophan

2016
Nicotinamide Adenine Dinucleotides Arrest Photoreduction of Class II DNA Photolyases in FADH
    Photochemistry and photobiology, 2018, Volume: 94, Issue:1

    Topics: Archaeal Proteins; Deoxyribodipyrimidine Photo-Lyase; Electron Transport; Flavin-Adenine Dinucleotide; Kinetics; Light; Methanosarcina; Molecular Conformation; Mutation; NAD; NADP; Oxidation-Reduction; Tryptophan

2018
Integrated constraints based analysis of an engineered violacein pathway in Escherichia coli.
    Bio Systems, 2018, Volume: 171

    Topics: Escherichia coli; Indoles; Metabolic Engineering; Models, Biological; NADP; Operon; Tryptophan

2018
Role of the glutaredoxin domain and FAD in the stabilization of thioredoxin glutathione reductase.
    Archives of biochemistry and biophysics, 2018, 10-15, Volume: 656

    Topics: Animals; Catalysis; Dithionitrobenzoic Acid; Fasciola; Flavin-Adenine Dinucleotide; Glutaredoxins; Helminth Proteins; Multienzyme Complexes; Mutation; NADH, NADPH Oxidoreductases; NADP; Protein Binding; Protein Conformation; Protein Domains; Protein Stability; Protein Unfolding; Thioredoxins; Tryptophan; Urea

2018
Single-cell redox states analyzed by fluorescence lifetime metrics and tryptophan FRET interaction with NAD(P)H.
    Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2019, Volume: 95, Issue:1

    Topics: Cytosol; Doxorubicin; Energy Metabolism; Flavin-Adenine Dinucleotide; Fluorescence; Fluorescence Resonance Energy Transfer; HeLa Cells; Humans; Microscopy, Fluorescence, Multiphoton; Mitochondria; NAD; NADP; Optical Imaging; Oxidation-Reduction; Oxidative Phosphorylation; Reactive Oxygen Species; Single-Cell Analysis; Tryptophan

2019
Direct Aromatic Nitration System for Synthesis of Nitrotryptophans in Escherichia coli.
    ACS synthetic biology, 2019, 04-19, Volume: 8, Issue:4

    Topics: Arginine; Bacillus subtilis; Biocatalysis; Biosynthetic Pathways; Biotechnology; Escherichia coli; Fermentation; Indoles; Metabolic Engineering; NADP; Nitric Oxide; Nitric Oxide Synthase; Streptomyces; Tryptophan

2019
Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression.
    Oncogene, 2020, Volume: 39, Issue:40

    Topics: Aldehyde Oxidase; Animals; Cell Line, Tumor; Disease Progression; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Kynurenine; Male; Metabolomics; Mice; NADP; Neoplasm Invasiveness; Neoplasm Staging; Nucleotides; Pentose Phosphate Pathway; RNA-Seq; Tissue Array Analysis; Tryptophan; Urinary Bladder; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays

2020
Rickettsial pathogen uses arthropod tryptophan pathway metabolites to evade reactive oxygen species in tick cells.
    Cellular microbiology, 2020, Volume: 22, Issue:10

    Topics: Anaplasma phagocytophilum; Animals; Hemin; Host-Pathogen Interactions; Hydrolases; Ixodes; Kynurenic Acid; Kynurenine; NADP; Reactive Oxygen Species; RNA Interference; Transaminases; Tryptophan; Tryptophan Oxygenase; Up-Regulation; Xanthurenates

2020
Production of indigo through the use of a dual-function substrate and a bifunctional fusion enzyme.
    Enzyme and microbial technology, 2020, Volume: 142

    Topics: Biotechnology; Escherichia coli; Indigo Carmine; NADP; Oxygenases; Tryptophan

2020
Characterization of Light-Induced, Short-Lived Interacting Radicals in the Active Site of Flavoprotein Ferredoxin-NADP
    Journal of the American Chemical Society, 2021, 02-24, Volume: 143, Issue:7

    Topics: Bacillus subtilis; Catalytic Domain; Electron Transport; Ferredoxin-NADP Reductase; Free Radicals; Light; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; NADP; Protein Binding; Quantum Theory; Tryptophan; Tyrosine

2021
Experimental Clarification of PRPS-1 Structural Essentials.
    Cell biochemistry and biophysics, 2022, Volume: 80, Issue:4

    Topics: Diphosphates; Histidine; Molecular Docking Simulation; NAD; NADP; Nucleotides; Phosphates; Phosphoribosyl Pyrophosphate; Purines; Pyridines; Pyrimidines; Ribose-Phosphate Pyrophosphokinase; Tryptophan

2022