tryptophan and n-methyl-3,4-methylenedioxyamphetamine

tryptophan has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.52)18.7374
1990's7 (33.33)18.2507
2000's7 (33.33)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aghajanian, GK; Bradberry, CW; Roth, RH; Sheldon, PW; Sprouse, JS1
Aghajanian, GK; Bradberry, CW; Roth, RH; Sprouse, JS2
Heninger, GR; Krystal, JH; Price, LH; Ricaurte, GA2
Cross, AJ; Goodwin, GM; Green, AR1
Huang, X; Kanthasamy, A; Nichols, DE; Sprague, JE1
Diksic, M; Mück-Seler, D; Takahashi, S1
Diksic, M; Mzengeza, S; Nishisawa, S1
Curran, HV; Verheyden, SL1
Gold, LH; Henriksen, SJ; Huitrón-Resendiz, S; Parsons, LH; Schroeder, R; Taffe, MA1
Riedel, WJ1
Bryant, SM; Kolodchak, J1
Cook, LJ; Cooper, JD; Roiser, JP; Rubinsztein, DC; Sahakian, BJ1
Ashford, KA; Christie, IN; Evans, AK; Lowry, CA; Reinders, N; Wakerley, JB1
Carhart-Harris, RL; Christmas, DM; Munafo, MR; Nutt, DJ; Wilson, SJ1
Blokland, A; Dawson, N; Ferrington, L; Kelly, PA; Prickaerts, J; Steinbusch, HW; van Donkelaar, EL1
Collins, CM; Elliott, JM; Kloek, J1
Benkelfat, C; Leyton, M; Pihl, RO; Regoli, M; Young, SN1
Benkelfat, C; Booij, L; Diksic, M; Gravel, P; Leyton, M; Pihl, RO; Regoli, M; Soucy, JP; Young, SN1
Cumming, P1

Reviews

1 review(s) available for tryptophan and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy").
    Psychopharmacology, 1995, Volume: 119, Issue:3

    Topics: Animals; Behavior, Animal; Fever; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Tryptophan

1995

Trials

2 trial(s) available for tryptophan and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
Altered response to tryptophan supplementation after long-term abstention from MDMA (ecstasy) is highly correlated with human memory function.
    Psychopharmacology, 2003, Volume: 169, Issue:1

    Topics: Adult; Affect; Amphetamine-Related Disorders; Attention; Cognition; Hallucinogens; Humans; Male; Memory; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Time Factors; Tryptophan; Verbal Behavior

2003
Equivalent effects of acute tryptophan depletion on REM sleep in ecstasy users and controls.
    Psychopharmacology, 2009, Volume: 206, Issue:2

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Hallucinogens; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Pain Measurement; Polysomnography; Reaction Time; Sleep, REM; Substance-Related Disorders; Time Factors; Tryptophan; Young Adult

2009

Other Studies

18 other study(ies) available for tryptophan and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
In vitro microdialysis: a novel technique for stimulated neurotransmitter release measurements.
    Journal of neuroscience methods, 1991, Volume: 36, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Electrophysiology; In Vitro Techniques; Male; Microchemistry; N-Methyl-3,4-methylenedioxyamphetamine; Neurotransmitter Agents; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1991
Sub-picogram determination of serotonin using HPLC with electrochemical detection for microdialysis studies of serotonin release.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Fluoxetine; Microchemistry; N-Methyl-3,4-methylenedioxyamphetamine; Raphe Nuclei; Rats; Secretory Rate; Serotonin; Tryptophan

1991
3,4-Methylenedioxymethamphetamine-induced release of serotonin and inhibition of dorsal raphe cell firing: potentiation by L-tryptophan.
    European journal of pharmacology, 1990, Mar-27, Volume: 178, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Brain Chemistry; Electrophysiology; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Raphe Nuclei; Rats; Serotonin; Tryptophan

1990
Neuroendocrine and mood responses to intravenous L-tryptophan in 3,4-methylenedioxymethamphetamine (MDMA) users. Preliminary observations.
    Archives of general psychiatry, 1989, Volume: 46, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Affect; Amphetamines; Designer Drugs; Female; Humans; Infusions, Intravenous; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Serotonin; Substance-Related Disorders; Tryptophan

1989
Responses to i.v. L-tryptophan in MDMA users.
    NIDA research monograph, 1989, Volume: 95

    Topics: 3,4-Methylenedioxyamphetamine; Adult; Affect; Amphetamines; Designer Drugs; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Receptors, Serotonin; Substance-Related Disorders; Tryptophan

1989
Attenuation of 3,4-methylenedioxymethamphetamine (MDMA) induced neurotoxicity with the serotonin precursors tryptophan and 5-hydroxytryptophan.
    Life sciences, 1994, Volume: 55, Issue:15

    Topics: 5-Hydroxytryptophan; Animals; Brain Diseases; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Endings; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan

1994
The effect of MDMA (3,4-methylenedioxymethamphetamine) on the 5-HT synthesis rate in the rat brain: an autoradiographic study.
    Brain research, 1998, Nov-09, Volume: 810, Issue:1-2

    Topics: Algorithms; Animals; Autoradiography; Brain; Brain Chemistry; Kinetics; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Serotonin; Serotonin Agents; Tryptophan

1998
Acute effects of 3,4-methylenedioxymethamphetamine on brain serotonin synthesis in the dog studied by positron emission tomography.
    Neurochemistry international, 1999, Volume: 34, Issue:1

    Topics: Animals; Blood-Brain Barrier; Brain; Dogs; Kinetics; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Serotonin Agents; Tomography, Emission-Computed; Tryptophan

1999
MDMA exposure alters cognitive and electrophysiological sensitivity to rapid tryptophan depletion in rhesus monkeys.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 76, Issue:1

    Topics: Animals; Brain; Cognition; Electrophysiology; Evoked Potentials, Auditory; Macaca mulatta; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Reaction Time; Tryptophan

2003
Cognitive changes after acute tryptophan depletion: what can they tell us?
    Psychological medicine, 2004, Volume: 34, Issue:1

    Topics: Alzheimer Disease; Cognition Disorders; Depressive Disorder, Major; Human Experimentation; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Tryptophan

2004
Serotonin syndrome resulting from an herbal detox cocktail.
    The American journal of emergency medicine, 2004, Volume: 22, Issue:7

    Topics: Adult; Antidepressive Agents, Second-Generation; Humans; Hypericum; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nonprescription Drugs; Plant Preparations; Self Medication; Serotonin Syndrome; Substance Withdrawal Syndrome; Tryptophan

2004
Association of a functional polymorphism in the serotonin transporter gene with abnormal emotional processing in ecstasy users.
    The American journal of psychiatry, 2005, Volume: 162, Issue:3

    Topics: Adult; Affective Symptoms; Depressive Disorder; Diagnosis, Dual (Psychiatry); Female; Genotype; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; N-Methyl-3,4-methylenedioxyamphetamine; Nerve Tissue Proteins; Neuropsychological Tests; Personality Inventory; Polymorphism, Genetic; Serotonin Plasma Membrane Transport Proteins; Substance-Related Disorders; Tryptophan

2005
Evidence for serotonin synthesis-dependent regulation of in vitro neuronal firing rates in the midbrain raphe complex.
    European journal of pharmacology, 2008, Aug-20, Volume: 590, Issue:1-3

    Topics: 5-Hydroxytryptophan; Animals; Dose-Response Relationship, Drug; Fluoxetine; Hydrazines; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Pargyline; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Time Factors; Tryptophan

2008
Acute tryptophan depletion potentiates 3,4-methylenedioxymethamphetamine-induced cerebrovascular hyperperfusion in adult male Wistar rats.
    Journal of neuroscience research, 2010, May-15, Volume: 88, Issue:7

    Topics: Animals; Binding, Competitive; Brain; Cerebral Arteries; Cerebrovascular Circulation; Cerebrovascular Disorders; Depressive Disorder; Disease Models, Animal; Hyperemia; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Rats; Rats, Wistar; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Tryptophan; Vasodilation

2010
Parallel changes in serotonin levels in brain and blood following acute administration of MDMA.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:1

    Topics: Animals; Brain; Frontal Lobe; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tryptophan

2013
The effect of acute tryptophan depletion on mood and impulsivity in polydrug ecstasy users.
    Psychopharmacology, 2014, Volume: 231, Issue:4

    Topics: Affect; Amphetamine-Related Disorders; Analysis of Variance; Cross-Over Studies; Diet; Double-Blind Method; Female; Humans; Impulsive Behavior; Male; N-Methyl-3,4-methylenedioxyamphetamine; Neuropsychological Tests; Serotonin Agents; Sex Factors; Time Factors; Tryptophan; Young Adult

2014
Brain serotonin synthesis in MDMA (ecstasy) polydrug users: an alpha-[(11) C]methyl-l-tryptophan study.
    Journal of neurochemistry, 2014, Volume: 131, Issue:5

    Topics: Adult; Antidepressive Agents, Second-Generation; Brain; Brain Mapping; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Positron-Emission Tomography; Self Report; Serotonin; Sex Factors; Substance-Related Disorders; Tryptophan; Young Adult

2014
Measuring effects of MDMA (ecstasy) abuse on the rate of cerebral serotonin synthesis.
    Journal of neurochemistry, 2014, Volume: 131, Issue:5

    Topics: Brain; Female; Humans; Male; N-Methyl-3,4-methylenedioxyamphetamine; Serotonin; Substance-Related Disorders; Tryptophan

2014