tryptophan and morphine

tryptophan has been researched along with morphine in 75 studies

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-199063 (84.00)18.7374
1990's3 (4.00)18.2507
2000's5 (6.67)29.6817
2010's3 (4.00)24.3611
2020's1 (1.33)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Bellman, K; Knegtel, RM; Settimo, L1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Badawy, AA; Evans, M3
Botting, R; Bower, S; Eason, CT; Hutson, PH; Wells, L1
Lytle, LD; Phebus, L1
Balsara, JJ; Chandorkar, AG; Jadhav, JH; Muley, MP1
Crossley, AW; Slater, P1
Brase, DA; Ho, IK; Loh, HH; Way, EL1
Burks, TF; Dafny, N3
Beani, L; Sarto, G; Siniscalchi, A1
Huidobro, F; Huidobro-Toro, JP; Leong Way, E1
Larson, AA; Takemori, AE2
Chou, PH; Han, CS; Jen, MF; Lu, CC; Lu, LH; Yang, TH1
Ahtee, L; Carlsson, A1
Rastogi, RB; Singhal, RL1
Flinchbaugh, C; Messing, RB; Waymire, JC2
Knapp, S; Mandell, AJ3
Ng, LK; Pérez-Cruet, J; Thoa, NB1
Abbott, FV; Etienne, P; Franklin, KB; Morgan, MJ; Sewitch, MJ; Young, SN1
Abbott, FV; English, MJ; Franklin, KB; Jeans, ME; Tasker, RA; Young, SN1
Franklin, KB; Kelly, SJ3
Chiang, CY; Xiang, XK1
Abbott, FV; Young, SN1
Correia, MA; Litman, DA1
Ho, IK; Loh, HH; Way, EL2
Grahame-Smith, DG; Marshall, I1
Oswald, I1
Hartmann, E1
Gessa, GL; Perez-Cruet, J; Stern, S; Tagliamonte, A; Tagliamonte, P1
el-Beih, ZM; Moussa, TA1
Afrikanov, II; Vedernikov, YP1
Norton, PR1
Vedernikov, YP1
Goodlet, I; Sugrue, MF1
Jacobs, BL1
Buxbaum, DM; Sanders-Busch, E; Yarbrough, GG1
Buxbaum, DM; Sanders-Bush, E; Yarbrough, GG1
Gessa, GL; Tagliamonte, A1
Lovenberg, W; Schechter, PJ; Sjoerdsma, A1
Bloom, FE; Costa, E1
Larin, F; Shein, HM; Wurtman, RJ1
Azmitia, EC1
Besson, JM; Coudert, D; Godefroy, F; Weil-Fugazza, J1
Botting, R; Morinan, A1
Sparber, SB; Takemori, AE; Yano, I1
Kruszewska, A; Langwiński, R1
Dennis, SG; Melzack, R1
Godefroy, F; Le Bars, D; Weil-Fugazza, J1
Badawy, AA; Morgan, CJ1
Badawy, AA; Evans, M; Punjani, NF1
Ghosh, S; Poddar, MK1
Daenens, P; Tytgat, J; Ulens, C; Van Boven, M1
Arun, P; Deepadevi, KV; Kurup, PA; Manojkumar, V; Ravikumar, A1
Arun, P; Devi, KV; Kurup, PA; Ravikumar, A1
HUIDOBRO, F1
SCHENKER, S; WARREN, KS1
CONTRERAS, E; CROXATTO, R; HUIDOBRO, F2
STEGER, C1
Gardell, LR; Hruby, VJ; Hunt, SP; King, T; Lai, J; Malan, PT; Ossipov, MH; Porreca, F; Vanderah, TW; Vardanyan, A; Wang, R1
Hruby, VJ; Keresztes, AI; Largent-Milnes, TM; Roeske, WR; Tumati, S; Vanderah, TW; Varga, EV; Yamamoto, T1
Chen, Y; Chen, Z; Li, C; Li, J; Lin, R; Lin, Y; Luo, C; Mo, Z; Xiao, S; Zhou, Q1
Bonse, A1

Reviews

4 review(s) available for tryptophan and morphine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Brain 5-hydroxytryptamine metabolism: adaptive changes after long-term administration of psychotropic drugs.
    General pharmacology, 1978, Volume: 9, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Brain; Cocaine; Diazepam; Hyperthyroidism; Hypothyroidism; Lithium; Morphine; Psychotropic Drugs; Rats; Receptors, Serotonin; Serotonin; Tryptophan; Tryptophan Hydroxylase

1978
Drugs and sleep.
    Pharmacological reviews, 1968, Volume: 20, Issue:4

    Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan

1968
Pharmacological studies of sleep and dreaming: chemical and clinical relationships.
    Biological psychiatry, 1969, Volume: 1, Issue:3

    Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan

1969

Trials

3 trial(s) available for tryptophan and morphine

ArticleYear
Acute tryptophan depletion blocks morphine analgesia in the cold-pressor test in humans.
    Psychopharmacology, 1992, Volume: 108, Issue:1-2

    Topics: Adolescent; Adult; Affect; Analgesics; Cold Temperature; Diet; Humans; Male; Morphine; Pain; Sensory Thresholds; Tryptophan

1992
Tryptophan-morphine interactions and postoperative pain.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:1

    Topics: Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Intraoperative Care; Morphine; Pain, Postoperative; Postoperative Care; Tryptophan

1990
Drugs and sleep.
    Pharmacological reviews, 1968, Volume: 20, Issue:4

    Topics: Aminobutyrates; Amphetamine; Animals; Antidepressive Agents; Barbiturates; Caffeine; Cats; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Drug Utilization; Ethanol; Hormones; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Lysergic Acid Diethylamide; Methods; Monoamine Oxidase Inhibitors; Morphine; Nicotine; Parasympatholytics; Parasympathomimetics; Phenytoin; Rats; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tryptophan

1968

Other Studies

69 other study(ies) available for tryptophan and morphine

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The effects of acute and chronic nicotine hydrogen (+)-tartrate administration and subsequent withdrawal on rat liver tryptophan pyrrolase activity and their comparison with those of morphine, phenobarbitone and ethanol.
    The Biochemical journal, 1975, Volume: 148, Issue:3

    Topics: Animals; Cycloheximide; Dactinomycin; Ethanol; Humans; Hydrocortisone; Liver; Male; Morphine; NADP; Nicotinyl Alcohol; Phenobarbital; Premedication; Pyridines; Rats; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Oxygenase

1975
Modification by monoamine oxidase inhibitors of the analgesic, hypothermic and toxic actions of morphine and pethidine in mice.
    The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:1

    Topics: Analgesics; Animals; Body Temperature; Brain Chemistry; Drug Interactions; Lethal Dose 50; Male; Meperidine; Mice; Monoamine Oxidase Inhibitors; Morphine; Reaction Time; Serotonin; Tryptophan

1978
Diet induced alterations in opiate analgesic drug potency.
    Proceedings of the Western Pharmacology Society, 1978, Volume: 21

    Topics: Analgesics, Opioid; Animals; Diet; Male; Morphine; Protein Deficiency; Rats; Reaction Time; Tryptophan

1978
Effect of drugs influencing central 5-hydroxytryptaminergic mechanisms on morphine-induced catalepsy in the rat.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:4

    Topics: Animals; Catalepsy; Central Nervous System; Clomipramine; Drug Interactions; Humans; Male; Methysergide; Morphine; Quipazine; Rats; Serotonin; Time Factors; Tryptophan

1979
The effect of morphine and some other narcotic analgesics on brain tryptophan concentrations.
    Journal of neuroscience research, 1979, Volume: 4, Issue:5-6

    Topics: Analgesics, Opioid; Animals; Brain; Dextrorphan; Female; Levorphanol; Mice; Morphine; Naloxone; Pain; Tryptophan

1979
Influence of L-tryptophan on morphine analgesia, tolerance and physical dependence.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 193, Issue:1

    Topics: Analgesia; Animals; Brain; Drug Interactions; Drug Tolerance; Fenclonine; Humans; Male; Mice; Mice, Inbred ICR; Morphine; Morphine Dependence; Rats; Reaction Time; Serotonin; Time Factors; Tryptophan; Tryptophan Hydroxylase

1975
Morphine and 5-hydroxytryptamine interactions in rat hypothalamus and pineal body.
    Experimental neurology, 1977, Volume: 55, Issue:2

    Topics: Acoustic Stimulation; Animals; Drug Interactions; Evoked Potentials; Fenclonine; Hypothalamus; Male; Morphine; Pineal Gland; Rats; Serotonin; Tryptophan

1977
5-hydroxytryptamine participation in morphine effects on sensory evoked responses.
    Proceedings of the Western Pharmacology Society, 1977, Volume: 20

    Topics: Acoustic Stimulation; Animals; Drug Interactions; Evoked Potentials; Fenclonine; Hypothalamus; Male; Morphine; Pineal Gland; Rats; Serotonin; Tryptophan

1977
5-HT and morphine interaction, effects on sensory input in caudate nucleus and substantia nigra.
    Neuropharmacology, 1977, Volume: 16, Issue:9

    Topics: Animals; Behavior, Animal; Caudate Nucleus; Cinanserin; Drug Interactions; Fenclonine; Male; Morphine; Motor Neurons; Naloxone; Rats; Serotonin; Substantia Nigra; Time Factors; Tryptophan

1977
Monoamines modulation of morphine action on pain threshold and cortical acetylcholine outflow.
    Pharmacological research communications, 1979, Volume: 11, Issue:8

    Topics: Acetylcholine; Animals; Biogenic Amines; Cerebral Cortex; Dextroamphetamine; Female; Fenclonine; Guinea Pigs; In Vitro Techniques; Male; Methyltyrosines; Morphine; Naloxone; Pain; Reserpine; Sensory Thresholds; Tryptophan

1979
Studies on tolerance development to single doses of morphine in mice.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 198, Issue:2

    Topics: 5,6-Dihydroxytryptamine; Animals; Brain; Cyclic AMP; Cycloheximide; Drug Tolerance; Female; Humans; Hydroxydopamines; Male; Methadone; Mice; Morphine; Pain; Reaction Time; Substance-Related Disorders; Time Factors; Tryptophan

1976
Effect of narcotics on the uptake of serotonin precursors by the rat brain.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Drug Implants; Levorphanol; Male; Morphine; Narcotics; Rats; Serotonin; Stereoisomerism; Time Factors; Tryptophan

1977
Effect of morphine on the fate of newly transported tryptophan and 5-hydroxytryptophan in brain of rats.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 205, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Biotransformation; Brain; Drug Interactions; Male; Morphine; Nerve Tissue Proteins; Pargyline; Rats; Serotonin; Tryptophan

1978
The role of central 5-hydroxytryptamine in acupuncture analgesia.
    Scientia Sinica, 1979, Volume: 22, Issue:1

    Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Acupuncture Therapy; Analgesia; Animals; Brain; Differential Threshold; Female; Injections, Intraperitoneal; Injections, Intraventricular; Morphine; Nociceptors; Rats; Serotonin; Spinal Cord; Tryptophan

1979
Dual action of methadone on 5-HT synthesis and metabolism.
    Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 307, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Hydroxyindoleacetic Acid; Male; Methadone; Morphine; Naloxone; Probenecid; Rats; Serotonin; Tryptophan; Tyrosine

1979
Tryptophan and 5-hydroxyindoles in different CNS regions following acute morphine.
    European journal of pharmacology, 1978, Mar-01, Volume: 48, Issue:1

    Topics: Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Morphine; Naloxone; Rats; Serotonin; Tryptophan

1978
Changes in brain tryptophan and tyrosine following acute and chronic morphine administration.
    Neuropharmacology, 1978, Volume: 17, Issue:6

    Topics: Animals; Brain Chemistry; Male; Morphine; Naloxone; Rats; Time Factors; Tryptophan; Tyrosine

1978
A neurobiological model for the symmetrical prophylactic action of lithium in bipolar affective disorder.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1976, Volume: 9, Issue:3

    Topics: Animals; Bipolar Disorder; Brain; Cocaine; Corpus Striatum; Humans; Kinetics; Lithium; Male; Mesencephalon; Models, Biological; Morphine; Rats; Serotonin; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase

1976
Acute effects of heroin and morphine on newly synthesized serotonin in rat brain.
    Life sciences, 1975, Aug-01, Volume: 17, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Brain Stem; Cerebral Cortex; Corpus Striatum; Diencephalon; Enzyme Induction; Heroin; Hydroxyindoleacetic Acid; Kinetics; Male; Morphine; Pargyline; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase

1975
The effects of ethanol on tryptophan pyrrolase activity and their comparison with those of phenobarbitone and morphine.
    Advances in experimental medicine and biology, 1975, Volume: 59

    Topics: Animals; Cricetinae; Ethanol; Fatty Acids, Nonesterified; Guinea Pigs; Humans; Kynurenine; Liver; Male; Morphine; Phenobarbital; Rats; Species Specificity; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase

1975
Current research in the indoleamine hypothesis of affective disorders.
    Psychopharmacology communications, 1975, Volume: 1, Issue:6

    Topics: Affective Symptoms; Animals; Bipolar Disorder; Brain; Cocaine; Humans; Indoles; Lithium; Male; Morphine; Rats; Serotonin; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase

1975
Sympathetic control of tryptophan uptake and morphine analgesia in stressed rats.
    European journal of pharmacology, 1986, Jul-15, Volume: 126, Issue:1-2

    Topics: Analgesia; Animals; Guanethidine; Hydroxyindoleacetic Acid; Male; Morphine; Pain; Rats; Restraint, Physical; Serotonin; Stress, Psychological; Sympathetic Nervous System; Tryptophan

1986
Does morphine enhance the release of 5-hydroxytryptamine in the rat spinal cord? An in vivo differential pulse voltammetry study.
    Brain research, 1987, May-19, Volume: 411, Issue:2

    Topics: Animals; Electrochemistry; Hydroxyindoleacetic Acid; Male; Morphine; Probenecid; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Stereoisomerism; Tryptophan; Urate Oxidase

1987
Effect of 5-hydroxytryptamine precursors on morphine analgesia in the formalin test.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:4

    Topics: 5-Hydroxytryptophan; Analgesia; Animals; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Formaldehyde; Hydroxyindoleacetic Acid; Male; Morphine; Pain Measurement; Rats; Serotonin; Tryptophan

1988
Elevated brain tryptophan and enhanced 5-hydroxytryptamine turnover in acute hepatic heme deficiency: clinical implications.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:2

    Topics: Animals; Brain; Cytochrome P-450 Enzyme Inhibitors; Disease Models, Animal; Heme; Liver; Liver Diseases; Male; Morphine; Porphyrias; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1985
An increase in tryptophan in brain may be a general mechanism for the effect of stress on sensitivity to pain.
    Neuropharmacology, 1985, Volume: 24, Issue:11

    Topics: Animals; Brain Chemistry; Male; Morphine; Pain; Rats; Restraint, Physical; Stress, Psychological; Time Factors; Tryptophan; Tyrosine

1985
Brain 5-hydroxytryptamine and cyclic AMP in morphine tolerance and dependence.
    Advances in biochemical psychopharmacology, 1974, Volume: 10

    Topics: 5-Hydroxytryptophan; Adrenergic beta-Antagonists; Analgesics; Animals; Body Weight; Brain; Brain Chemistry; Cyclic AMP; Cycloheximide; Drug Tolerance; Fenclonine; Humans; Mice; Morphine; Morphine Dependence; Naloxone; Rats; Serotonin; Serotonin Antagonists; Time Factors; Tryptamines; Tryptophan; Tryptophan Hydroxylase

1974
Evidence against a role of brain 5-hydroxytryptamine in the development of physical dependence upon morphine in mice.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:3

    Topics: Animals; Body Weight; Brain Chemistry; Drug Interactions; Female; Fenclonine; Humans; Kinetics; Mice; Mice, Inbred Strains; Monoamine Oxidase Inhibitors; Morphine; Morphine Dependence; Motor Activity; Naloxone; Serotonin; Substance Withdrawal Syndrome; Tranylcypromine; Tryptophan

1971
Effect of psychotropic drugs on tryptophan concentration in the rat brain.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3

    Topics: Alkaloids; Animals; Apomorphine; Aporphines; Body Temperature; Brain Chemistry; Butyrates; Chlorpromazine; Cold Temperature; Cyclic AMP; Dextroamphetamine; Fenclonine; Fenfluramine; Haloperidol; Hot Temperature; Hydroxybutyrates; Hydroxyindoleacetic Acid; Lithium; Male; Methyltyrosines; Morphine; Nucleosides; Phenelzine; Phenmetrazine; Probenecid; Rats; Reserpine; Serotonin; Tryptophan; Tyrosine

1971
Effects of morphine on the Golgi apparatus and mitochondria of mammalian neurones.
    La Cellule, 1972, Volume: 69, Issue:2

    Topics: Animals; Cell Nucleus; Ganglia, Spinal; Glutathione; Golgi Apparatus; Guinea Pigs; Histocytochemistry; Inclusion Bodies; Injections, Intraperitoneal; Lipids; Mitochondria; Morphine; Neurons; Phospholipids; Riboflavin; Tryptophan; Tyrosine

1972
Cyclic adenosine monophosphate antagonism of morphine analgesia.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:2

    Topics: Adenylyl Cyclases; Analgesia; Animals; Brain; Cyclic AMP; Dihydroxyphenylalanine; Drug Interactions; Drug Tolerance; Male; Mice; Mice, Inbred ICR; Morphine; Pargyline; Serine; Theophylline; Time Factors; Tryptophan

1973
On the role of a central adrenergic mechanism in morphine analgesic action.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:12

    Topics: Amphetamine; Animals; Brain; Cocaine; Disulfiram; Drug Synergism; Female; Iproniazid; Methyldopa; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan

1969
The effects of drugs on barbiturate withdrawal convulsions in the rat.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:10

    Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Ethanol; Ethosuximide; Female; Humans; Hydrazines; Hypnotics and Sedatives; Meprobamate; Methyltyrosines; Monoamine Oxidase Inhibitors; Morphine; Phenylalanine; Primidone; Rats; Reserpine; Seizures; Serotonin; Substance Withdrawal Syndrome; Tryptophan

1970
The role of brain catecholamines in morphine analgesic action in morphine tolerant rats.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:3

    Topics: Amphetamine; Analgesics; Animals; Brain; Catecholamines; Cocaine; Disulfiram; Drug Synergism; Drug Tolerance; Female; Iproniazid; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan

1970
Effect of acutely administered analgesic drugs on rat brain serotonin turnover.
    European journal of pharmacology, 1974, Volume: 29, Issue:2

    Topics: Analgesics; Animals; Brain; Brain Chemistry; Clomipramine; Dopamine; Hydroxyindoleacetic Acid; Kinetics; Male; Meperidine; Methadone; Morphine; Naloxone; Nialamide; Norepinephrine; Pargyline; Pentazocine; Rats; Serotonin; Stimulation, Chemical; Tranylcypromine; Tryptophan

1974
Effect of two dopamine receptor blockers on a serotonin-mediated behavioral syndrome in rats.
    European journal of pharmacology, 1974, Volume: 27, Issue:3

    Topics: Animals; Behavior, Animal; Benzoates; Dopamine; Dose-Response Relationship, Drug; Humans; Injections, Intraperitoneal; Locomotion; Male; Morphine; Motor Activity; Pargyline; Pimozide; Rats; Receptors, Drug; Serotonin; Spiro Compounds; Stereotyped Behavior; Tryptophan

1974
Increased serotonin turnover in acutely morphine-treated mice.
    Biochemical pharmacology, 1972, Oct-01, Volume: 21, Issue:19

    Topics: Animals; Brain Chemistry; Cerebral Cortex; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred ICR; Morphine; Probenecid; Serotonin; Time Factors; Tritium; Tryptophan

1972
Biogenic amines and narcotic effects. II. Serotonin turnover in the rat after acute and chronic morphine administration.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:2

    Topics: Animals; Brain Chemistry; Drug Tolerance; Hydroxyindoleacetic Acid; Male; Morphine; Motor Activity; Naloxone; Pargyline; Probenecid; Rats; Serotonin; Time Factors; Tritium; Tryptophan; Tryptophan Hydroxylase

1973
Possible role of free serum tryptophan in the control of brain tryptophan level and serotonin synthesis.
    Advances in biochemical psychopharmacology, 1974, Volume: 11, Issue:0

    Topics: Amino Acids; Animals; Apomorphine; Blood-Brain Barrier; Brain; Chlorpromazine; Cold Temperature; Desipramine; Fenfluramine; Haloperidol; Hydroxyindoleacetic Acid; Kinetics; Methyltyrosines; Morphine; Neurons; Phenelzine; Protein Binding; Rats; Serotonin; Stimulation, Chemical; Tryptophan; Tryptophan Hydroxylase

1974
Narcotic drugs: effects on the serotonin biosynthetic systems of the brain.
    Science (New York, N.Y.), 1972, Sep-29, Volume: 177, Issue:4055

    Topics: Animals; Brain; Carbon Isotopes; Cocaine; Male; Mesencephalon; Mixed Function Oxygenases; Morphine; Nerve Endings; Rats; Serotonin; Synaptic Vesicles; Synaptosomes; Time Factors; Tryptophan

1972
Dissociation of morphine tolerance and dependence from brain serotonin synthesis rate in mice.
    Biochemical pharmacology, 1972, Mar-01, Volume: 21, Issue:5

    Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Drug Tolerance; Humans; Kinetics; Male; Mice; Mixed Function Oxygenases; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Morphine; Pargyline; Serotonin; Substance-Related Disorders; Tryptophan

1972
The effects of drugs on serotonergic nerve terminals.
    Advances in cytopharmacology, 1971, Volume: 1

    Topics: Animals; Brain; Catecholamines; Cerebellum; Histocytochemistry; Hydroxyindoleacetic Acid; Hydroxylation; Kinetics; Lysergic Acid Diethylamide; Microscopy, Electron; Monoamine Oxidase Inhibitors; Morphine; Nerve Endings; Norepinephrine; Pargyline; Probenecid; Rats; Serotonin; Synapses; Time Factors; Tryptophan

1971
Lack of a direct effect of morphine on the synthesis of pineal 14-C-indoles in organ culture.
    Life sciences, 1970, Jan-01, Volume: 9, Issue:1

    Topics: Animals; Carbon Isotopes; Culture Techniques; Female; Melatonin; Morphine; Norepinephrine; Organ Culture Techniques; Pineal Gland; Protein Biosynthesis; Rats; Serotonin; Tryptophan

1970
Tryptophan hydroxylase changes in midbrain of the rat after chronic morphine administration.
    Life sciences. Pt. 1: Physiology and pharmacology, 1970, Jun-01, Volume: 9, Issue:11

    Topics: Animals; Carbon Isotopes; Female; Mesencephalon; Mixed Function Oxygenases; Morphine; Rats; Serotonin; Tryptophan

1970
Effect of acute administration of morphine on newly synthesized 5-hydroxytryptamine in spinal cord of the rat.
    Brain research, 1980, Oct-20, Volume: 199, Issue:2

    Topics: Animals; Brain; Hydroxyindoleacetic Acid; Kinetics; Male; Morphine; Naloxone; Organ Specificity; Rats; Serotonin; Spinal Cord; Tryptophan

1980
Involvement of 5-hydroxytryptamine in the analgesic action of pethidine and morphine in mice.
    British journal of pharmacology, 1982, Volume: 75, Issue:4

    Topics: Analgesics; Animals; Body Temperature; Brain Chemistry; Fenclonine; Fenfluramine; Hydroxyindoleacetic Acid; Male; Meperidine; Mice; Morphine; Reaction Time; Serotonin; Tryptophan

1982
Alterations in morphine-induced analgesia and tolerance by various compounds.
    Substance and alcohol actions/misuse, 1980, Volume: 1, Issue:2

    Topics: Aminooxyacetic Acid; Animals; Bucladesine; Cyclic GMP; Drug Tolerance; Humans; Male; Mice; Morphine; Morphine Dependence; Pain; Tryptophan

1980
The role of central serotoninergic neurotransmission in the morphine abstinence syndrome in rats.
    Drug and alcohol dependence, 1983, Volume: 12, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Brain; Fenclonine; Humans; Male; Metergoline; Morphine; Rats; Rats, Inbred Strains; Serotonin; Substance Withdrawal Syndrome; Synaptic Transmission; Tryptophan

1983
Pain modulation by 5-hydroxytryptaminergic agents and morphine as measured by three pain tests.
    Experimental neurology, 1980, Volume: 69, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Fenclonine; Male; Methysergide; Morphine; Naloxone; Nociceptors; Rats; Serotonin; Tryptophan

1980
Increase in 5-HT synthesis in the dorsal part of the spinal cord, induced by a nociceptive stimulus: blockade by morphine.
    Brain research, 1984, Apr-16, Volume: 297, Issue:2

    Topics: Afferent Pathways; Animals; Brain Stem; Male; Morphine; Naloxone; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spinal Cord; Tail; Tryptophan

1984
Evidence that stress augments morphine analgesia by increasing brain tryptophan.
    Neuroscience letters, 1984, Feb-24, Volume: 44, Issue:3

    Topics: Analgesia; Animals; Biomechanical Phenomena; Brain; Male; Morphine; Rats; Rats, Inbred Strains; Reaction Time; Restraint, Physical; Serotonin; Stress, Physiological; Tryptophan

1984
Tryptophan and tryptophan pyrrolase in haem regulation. The role of lipolysis and direct displacement of serum-protein-bound tryptophan in the opposite effects of administration of endotoxin, morphine, palmitate, salicylate and theophylline on rat liver 5
    The Biochemical journal, 1982, Sep-15, Volume: 206, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Animals; Carboxylic Acids; Endotoxins; Heme; Lipolysis; Lipopolysaccharides; Liver; Male; Morphine; Rats; Rats, Inbred Strains; Theophylline; Tryptophan; Tryptophan Oxygenase

1982
The role of liver tryptophan pyrrolase in the opposite effects of chronic administration and subsequent withdrawal of drugs of dependence on rat brain tryptophan metabolism.
    The Biochemical journal, 1981, Apr-15, Volume: 196, Issue:1

    Topics: Animals; Brain; Humans; Liver; Male; Methylphenazonium Methosulfate; Morphine; Naloxone; Nicotine; Phenobarbital; Rats; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase

1981
Rapid reversal by naloxone of the chronic effects of morphine on rat liver and brain tryptophan metabolism.
    British journal of pharmacology, 1981, Volume: 74, Issue:3

    Topics: Animals; Brain; Liver; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1981
Higher environmental temperature-induced increase in body temperature: involvement of serotonin in GABA mediated interaction of opioidergic system.
    Neurochemical research, 1993, Volume: 18, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Body Temperature; Endorphins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hot Temperature; Hydroxyindoleacetic Acid; Male; Methysergide; Morphine; Naloxone; Physostigmine; Rats; Serotonin; Tryptophan

1993
Interaction of p-fluorofentanyl on cloned human opioid receptors and exploration of the role of Trp-318 and His-319 in mu-opioid receptor selectivity.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:3

    Topics: Animals; Cloning, Molecular; Designer Drugs; Fentanyl; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Histidine; Humans; Ligands; Morphine; Mutation; Narcotics; Oocytes; Patch-Clamp Techniques; Piperidines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Sufentanil; Tryptophan; Xenopus laevis

2000
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
    Neurology India, 2000, Volume: 48, Issue:3

    Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythrocytes; Fatty Acids, Nonesterified; Female; Glioma; Glycine Agents; Humans; Hydroxymethylglutaryl CoA Reductases; Kynurenic Acid; Magnesium; Male; Microvascular Angina; Middle Aged; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Parkinson Disease; Quinolinic Acid; Schizophrenia; Serum Albumin; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine; Ubiquinone

2000
Endogenous strychnine, nicotine, and morphine--description of hypo and hyper-strychninergic, nicotinergic and morphinergic state in relation to neuropsychiatric diseases.
    Indian journal of experimental biology, 2000, Volume: 38, Issue:6

    Topics: Adult; Alkaloids; Brain Neoplasms; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Glioma; Humans; Male; Mental Disorders; Middle Aged; Morphine; Neoplasm Proteins; Nervous System Diseases; Nicotine; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine

2000
EFFECTS OF SOME INDOLES AND ACRIDINE DERIVATIVES ON THE ANALGESIC EFFECT OF MORPHINE.
    Acta physiologica latino americana, 1963, Volume: 13

    Topics: Acridines; Analgesia; Analgesics; Indoles; Mice; Morphine; Nalorphine; Narcotic Antagonists; Pain; Pain Management; Reaction Time; Research; Toxicology; Tremor; Tryptophan

1963
DRUGS RELATED TO THE EXACERBATION OR AMELIORATION OF HEPATIC COMA AND THEIR EFFECTS ON AMMONIA TOXICITY.
    Clinical science, 1963, Volume: 25

    Topics: Acetazolamide; Ammonia; Ammonium Chloride; Arginine; Chlorothiazide; Cortisone; Formaldehyde; Glutamates; Hepatic Encephalopathy; Hydrogen-Ion Concentration; Iproniazid; Mice; Morphine; Paraldehyde; Pentobarbital; Phenobarbital; Research; Toxicology; Tryptophan

1963
STUDIES ON MORPHINE. III. ACTION OF METABOLIC PRECURSORS TO SEROTONIN AND NORADRENALINE AND RELATED SUBSTANCES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
    Archives internationales de pharmacodynamie et de therapie, 1963, Dec-01, Volume: 146

    Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Ergot Alkaloids; Iproniazid; Kynurenine; Lysergic Acid Diethylamide; Methyldopa; Mice; Morphine; Nalorphine; Norepinephrine; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Research; Serotonin; Shikimic Acid; Toxicology; Tryptophan; Tyrosine

1963
STUDIES ON MORPHINE. IV. EFFECTS OF SOME METABOLITES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
    Archives internationales de pharmacodynamie et de therapie, 1963, Dec-01, Volume: 146

    Topics: Alanine; Cyanides; Fluoroacetates; Glutamine; Iodoacetates; Mice; Morphine; NAD; Nalorphine; Niacin; Niacinamide; Pharmacology; Pyridines; Pyridoxine; Research; Serine; Toxicology; Tryptophan

1963
[ANESTHESIA IN SURGERY OF THE "CARCINOID SYNDROME"].
    Minerva anestesiologica, 1964, Volume: 30

    Topics: Anesthesia; Anesthesiology; Atropine; Humans; Malignant Carcinoid Syndrome; Metabolism; Morphine; Nitrous Oxide; Oxygen; Postoperative Care; Serotonin; Succinylcholine; Surgical Procedures, Operative; Thiopental; Tryptophan

1964
Role of NK-1 neurotransmission in opioid-induced hyperalgesia.
    Pain, 2005, Volume: 116, Issue:3

    Topics: Animals; Cell Count; Drug Interactions; Hot Temperature; Hyperalgesia; Immunohistochemistry; Male; Mice; Mice, Knockout; Morphine; Narcotics; Neurokinin-1 Receptor Antagonists; Pain Measurement; Protein Transport; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Spinal Cord; Substance P; Synaptic Transmission; Time Factors; Touch; Tryptophan

2005
Tachykinin NK₁ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation.
    European journal of pharmacology, 2012, Jun-05, Volume: 684, Issue:1-3

    Topics: Analgesics, Opioid; Animals; Astrocytes; Biomarkers; CD11b Antigen; Hyperalgesia; Male; Microglia; Morphine; Nerve Tissue Proteins; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance Withdrawal Syndrome; Tryptophan; Tumor Necrosis Factor-alpha; Up-Regulation

2012
Ginsenoside Rg1 mitigates morphine dependence via regulation of gut microbiota, tryptophan metabolism, and serotonergic system function.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 150

    Topics: Animals; Dysbiosis; Gastrointestinal Microbiome; Ginsenosides; Mice; Morphine; Morphine Dependence; RNA, Ribosomal, 16S; Serotonin; Tryptophan

2022
[On the occurrence of pterins, tryptophan and its derivatives in various organs of the white mutant of Drosophila melanogaster].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1969, Volume: 24, Issue:1

    Topics: Adipose Tissue; Animals; Chromatography, Paper; Drosophila; Feces; Female; Kynurenine; Male; Malpighian Tubules; Meconium; Molecular Biology; Mutation; Ovary; Pterins; Testis; Tryptophan

1969