tryptophan and methyldopa

tryptophan has been researched along with methyldopa in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199037 (90.24)18.7374
1990's0 (0.00)18.2507
2000's2 (4.88)29.6817
2010's2 (4.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellman, K; Knegtel, RM; Settimo, L1
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Luchins, D1
Chouinard, G; Jones, BD1
Parent, A; Poitras, D1
Kilbinger, H; Racké, K; Schwörer, H1
Atkins, FL; Beaven, MA; Keiser, HR1
Curzon, G; Green, AR1
Modigh, K1
Gal, EM; Marshall, FD; Morgan, M1
Haljasmaa, O; Ross, SB2
Robinson, D; Sharman, DF1
Afrikanov, II; Vedernikov, YP1
Dineen, JK; Love, RJ; Rothwell, TL1
Presthus, J1
Ashcroft, GW; Crawford, TB; Eccleston, D1
De Ropp, RS; Furst, A1
Kawabata, K1
Ashcroft, GW; Eccleston, D; Lutz, W; Moir, AT; O'Mahoney, DP; Parker-Rhodes, A1
Dreux, C; Ingrand, J1
Ashcroft, GW; Berger, RJ; Eccleston, D; Evans, JI; Oswald, I; Thacore, VR1
Fernstrom, JD1
Gelber, LR; Neumeyer, JL1
Fernstrom, JD; Goldberg, IM; Sved, AF1
Neumann, NU1
Bey, P; Jung, MJ; Koch-Weser, J; Palfreyman, MG; Sjoerdsma, A; Wagner, J; Zraïka, M1
ADICOFF, A; ALEXANDER, CS; DAVIS, RB1
CARTIER, P; FABLET, J; GEFFROY, Y; LEGRAND, M; LEMOINE, P; MALANDRIN, C; MOREAU, J1
KIMURA, S; MIKUNI, M; TAKESHIMA, M1
CONTRERAS, E; CROXATTO, R; HUIDOBRO, F1
BURKARD, WP; GEY, KF; PLETSCHER, A3
JACOBY, GA; LADU, BN1
CARDOT, J1
FLOCK, EV; KOTTKE, BA; SHEPS, SG; TYCE, GM1
ANDEN, NE; ROOS, BE; WERDINIUS, B1
CALESNICK, B1

Reviews

3 review(s) available for tryptophan and methyldopa

ArticleYear
Biogenic amines and affective disorders. A critical analysis.
    International pharmacopsychiatry, 1976, Volume: 11, Issue:3

    Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain Chemistry; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Fenclonine; Fusaric Acid; Humans; Levodopa; Lithium; Methyldopa; Methyltyrosines; Methysergide; Monoamine Oxidase Inhibitors; Phenylketonurias; Reserpine; Tryptophan

1976
[Other trials with drug therapy in parkinsonism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Rats; Serine; Time Factors; Tryptophan; Tyrosine

1973
Role of precursor availability in control of monoamine biosynthesis in brain.
    Physiological reviews, 1983, Volume: 63, Issue:2

    Topics: Animals; Appetite; Blood Pressure; Brain; Brain Chemistry; Catecholamines; Diabetes Mellitus; Diet; Growth Hormone; Humans; Liver Cirrhosis; Methyldopa; Pain; Phenylketonurias; Protein Binding; Rats; Serotonin; Serum Albumin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase

1983

Trials

2 trial(s) available for tryptophan and methyldopa

ArticleYear
Biogenic amines and affective disorders. A critical analysis.
    International pharmacopsychiatry, 1976, Volume: 11, Issue:3

    Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain Chemistry; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Fenclonine; Fusaric Acid; Humans; Levodopa; Lithium; Methyldopa; Methyltyrosines; Methysergide; Monoamine Oxidase Inhibitors; Phenylketonurias; Reserpine; Tryptophan

1976
Evidence of brain dopamine deficiency in schizophrenia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1979, Volume: 24, Issue:7

    Topics: Benserazide; Brain; Chlorpromazine; Dopamine; Double-Blind Method; Drug Therapy, Combination; Humans; Methyldopa; Receptors, Dopamine; Rubidium; Schizophrenia; Serotonin; Tryptophan

1979

Other Studies

37 other study(ies) available for tryptophan and methyldopa

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A fluorescence microscopic study of the distribution of monoamines in the hypothalamus of the cat.
    Journal of morphology, 1975, Volume: 145, Issue:4

    Topics: Animals; Biogenic Amines; Catecholamines; Cats; Female; Histocytochemistry; Hypothalamus; Injections, Intraperitoneal; Male; Median Eminence; Methyldopa; Microscopy, Fluorescence; Neurons; Nialamide; Reserpine; Serotonin; Tryptophan

1975
Spontaneous release of endogenous 5-hydroxytryptamine and 5-hydroxyindoleacetic acid from the isolated vascularly perfused ileum of the guinea-pig.
    Neuroscience, 1987, Volume: 21, Issue:1

    Topics: Animals; Calcium; Guinea Pigs; Hydroxyindoleacetic Acid; Ileum; Imipramine; In Vitro Techniques; Male; Methyldopa; Myenteric Plexus; Pargyline; Perfusion; Portal Vein; Serotonin; Tetrodotoxin; Tryptophan

1987
Dopa decarboxylase in medullary carcinoma of the thyroid.
    The New England journal of medicine, 1973, Sep-13, Volume: 289, Issue:11

    Topics: Adrenal Gland Neoplasms; Amine Oxidase (Copper-Containing); Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carcinoma; Cresols; Dihydroxyphenylalanine; Dopa Decarboxylase; Histamine; Histidine; Humans; Hydrazines; Hydroxylamines; Methyldopa; Methylhistidines; Norepinephrine; Pheochromocytoma; Serotonin; Thyroid Gland; Thyroid Neoplasms; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase

1973
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1970
Functional aspects of 5-hydroxytryptamine turnover in the central nervous system.
    Acta physiologica Scandinavica. Supplementum, 1974, Volume: 403

    Topics: 5-Hydroxytryptophan; Acetamides; Animals; Antidepressive Agents; Brain; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Fenclonine; Humans; Hydrazines; Imipramine; Male; Methyldopa; Motor Activity; Nialamide; Receptors, Drug; Reserpine; Serotonin; Stimulation, Chemical; Stress, Psychological; Tryptophan; Tyrosine

1974
Studies on the metabolism of 5-hydroxytryptamine (serotonin). IV. The effect of various drugs on the in vivo hydroxylation of tryptophan by the brain tissue.
    Life sciences, 1965, Volume: 4, Issue:18

    Topics: Animals; Birds; Brain; Chromatography; Hydrazines; In Vitro Techniques; Intestine, Small; Kidney; Liver; Methotrexate; Methyldopa; Mixed Function Oxygenases; Myocardium; Rats; Reserpine; Serotonin; Tryptophan

1965
Inhibition of liver phenylalanine and tryptophan hydroxylating enzyme systems in vitro and in vivo.
    Acta pharmacologica et toxicologica, 1966, Volume: 24, Issue:1

    Topics: Aminopterin; Animals; Brain Chemistry; Coumarins; Enzyme Induction; Enzymes; Flavonoids; In Vitro Techniques; Liver; Liver Extracts; Methyldopa; Mice; Mixed Function Oxygenases; NAD; NADP; Phenylacetates; Phenylalanine; Rats; Serotonin; Tryptophan

1966
The action of 2-amino-tetralin (beta-tetrahydronaphthylamine) on the metabolism of 5-hydroxytryptamine in the brain of the mouse.
    British journal of pharmacology and chemotherapy, 1967, Volume: 29, Issue:3

    Topics: Animals; Brain; Hydrazines; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Male; Methyldopa; Mice; Naphthalenes; Serotonin; Tryptophan

1967
On the role of a central adrenergic mechanism in morphine analgesic action.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:12

    Topics: Amphetamine; Animals; Brain; Cocaine; Disulfiram; Drug Synergism; Female; Iproniazid; Methyldopa; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan

1969
The role of pharmacologically-active amines in resistance to Trichostrongylus colubriformis in the guinea-pig.
    Immunology, 1971, Volume: 21, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Basophils; Eosinophils; Feces; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histidine; Hydrazines; Immunity; Immunization; Lymph Nodes; Lymphocytes; Methyldopa; Methysergide; Parasite Egg Count; Promethazine; Pyrroles; Reserpine; Serotonin; Transplantation, Homologous; Trichostrongyloidiasis; Tryptophan

1971
5-hydroxyindole metabolism in rat brain. A study of intermediate metabolism using the technique of tryptophan loading. II. Applications and drug studies.
    Journal of neurochemistry, 1965, Volume: 12, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Blood Chemical Analysis; Brain; Carboxy-Lyases; Enzymes; Hydroxyindoleacetic Acid; Injections, Intramuscular; Injections, Intraperitoneal; Iproniazid; Methyldopa; Rats; Serotonin; Tryptophan

1965
Effect of analogs of phenylalanine and tryptophan on kinetics of DOPA decarboxylase in rat brain.
    Brain research, 1966, Volume: 2, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Male; Methyldopa; Phenylalanine; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine

1966
[Autoradiographic study of the basal clear cell in the gastric gland].
    Archivum histologicum Japonicum = Nihon soshikigaku kiroku, 1967, Volume: 28, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Chromium; Dihydroxyphenylalanine; Gastric Mucosa; Histocytochemistry; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Methyldopa; Mice; Rats; Reserpine; Serotonin; Silver; Tryptophan; Tyrosine

1967
A comparison of 5-hydroxyindoles in various regions of dog brain and cerebrospinal fluid.
    Journal of neurochemistry, 1968, Volume: 15, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Brain Stem; Carboxy-Lyases; Dogs; Hydroxyindoleacetic Acid; Methyldopa; Oxidoreductases; Serotonin; Statistics as Topic; Tryptophan

1968
[Carcinoid syndrome (apropos of 1 case). II. Biologic study and therapeutic note].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1967, Feb-23, Volume: 119, Issue:4

    Topics: Autoradiography; Carbon Isotopes; Humans; Indoles; Kynurenine; Lysergic Acid Diethylamide; Malignant Carcinoid Syndrome; Methyldopa; Phenothiazines; Serotonin; Tryptamines; Tryptophan

1967
Some experiments in the chemistry of normal sleep.
    The British journal of psychiatry : the journal of mental science, 1966, Volume: 112, Issue:485

    Topics: Arousal; Attention; Brain; Electroencephalography; Eye Movements; Humans; Methionine; Methyldopa; Methysergide; Serotonin; Sleep; Tryptophan; Tyrosine; Urine

1966
Determination of the enantiomeric purity of levodopa, methyldopa, carbidopa and tryptophan by use of chiral mobile phase high-performance liquid chromatography.
    Journal of chromatography, 1983, Mar-04, Volume: 257, Issue:2

    Topics: Capsules; Carbidopa; Chromatography, High Pressure Liquid; Copper; Copper Sulfate; Drug Contamination; Levodopa; Methyldopa; Phenylalanine; Stereoisomerism; Tablets; Tryptophan

1983
Dietary protein intake influences the antihypertensive potency of methyldopa in spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Amino Acids; Animals; Blood Pressure; Brain; Diet; Dietary Proteins; Hypertension; Male; Methyldopa; Rats; Spleen; Tryptophan

1980
[Drug therapy in tardive dyskinesia].
    Fortschritte der Medizin, 1980, Nov-13, Volume: 98, Issue:42

    Topics: Diagnosis, Differential; Dopamine Antagonists; Dyskinesia, Drug-Induced; Humans; Lithium; Methyldopa; Parasympathomimetics; Pyridoxine; Tiapamil Hydrochloride; Tranquilizing Agents; Tryptophan

1980
Further studies on the inhibition of monoamine synthesis by monofluoromethyldopa.
    British journal of pharmacology, 1980, Volume: 70, Issue:4

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Catecholamines; Dopamine; Male; Methyldopa; Mice; Serotonin; Time Factors; Tryptophan

1980
Metabolic studies in carcinoid syndrome: observations on use of alpha-methyl DOPA, isonicotinic acid hydrazide and selective tryptophan deficiency.
    Metabolism: clinical and experimental, 1961, Volume: 10

    Topics: Dihydroxyphenylalanine; Humans; Isoniazid; Malignant Carcinoid Syndrome; Methyldopa; Serotonin; Tryptophan

1961
[Trial of alpha-methyl-dopa in a case of carcinoidosis].
    Pathologie et biologie, 1962, Volume: 10

    Topics: Carcinoid Tumor; Dihydroxyphenylalanine; Humans; Methyldopa; Serotonin; Tryptophan

1962
[TRIALS OF A NEW ANTIHYPERTENSIVE, ALPHA-METHYL-DOPA (ALDOMET) WITH SPECIAL REFERENCE TO CHANGES IN RETINAL BLOOD FLOW].
    Rinsho ganka. Japanese journal of clinical ophthalmology, 1963, Volume: 17

    Topics: Angiotensins; Antihypertensive Agents; Blood Circulation; Blood Pressure; Blood Pressure Determination; Dopamine; Epinephrine; Hemodynamics; Methyldopa; NAD; Norepinephrine; Phenylalanine; Renin; Retinal Vessels; Serotonin; Tryptophan; Tyrosine

1963
STUDIES ON MORPHINE. III. ACTION OF METABOLIC PRECURSORS TO SEROTONIN AND NORADRENALINE AND RELATED SUBSTANCES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
    Archives internationales de pharmacodynamie et de therapie, 1963, Dec-01, Volume: 146

    Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Ergot Alkaloids; Iproniazid; Kynurenine; Lysergic Acid Diethylamide; Methyldopa; Mice; Morphine; Nalorphine; Norepinephrine; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Research; Serotonin; Shikimic Acid; Toxicology; Tryptophan; Tyrosine

1963
INHIBITION OF THE HYDROXYLATION OF TRYPTOPHAN AND PHENYLALANINE BY ALPHA-METHYL-DOPA AND SIMILAR COMPOUNDS.
    Life sciences (1962), 1964, Volume: 3

    Topics: Antihypertensive Agents; Carboxy-Lyases; Enzyme Inhibitors; Hydroxylation; Liver; Metabolism; Methyldopa; Mixed Function Oxygenases; Pharmacology; Phenylalanine; Rats; Research; Research Design; Tissue Culture Techniques; Tryptophan; Tyrosine

1964
STUDIES ON THE SPECIFICITY OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: 5-Hydroxytryptophan; Alanine; Amphetamine; Benzoates; Butyrates; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Ephedrine; Indoleacetic Acids; Ketoglutaric Acids; Lactates; Liver; Mandelic Acids; Methyldopa; Normetanephrine; Pharmacology; Phenylacetates; Phenylalanine; Propionates; Rats; Research; Transaminases; Tryptophan; Tyramine; Tyrosine; Tyrosine Transaminase

1964
[INHIBITION OF TRYPTOPHAN HYDROXYLASE BY ALPHA-METHYLDOPA].
    Helvetica physiologica et pharmacologica acta, 1964, Volume: 22

    Topics: Amino Acids; Enzyme Inhibitors; Methyldopa; Mixed Function Oxygenases; Phenylalanine; Tryptophan; Tryptophan Hydroxylase

1964
INHIBITORS OF THE ENZYMATIC HYDROXYLATION OF PHENYLALANINE AND TRYPTOPHAN BY RAT LIVER EXTRACT IN VITRO.
    Life sciences (1962), 1964, Volume: 3

    Topics: Enzyme Inhibitors; Hydroxylation; In Vitro Techniques; Liver; Liver Extracts; Methyldopa; Mixed Function Oxygenases; Pharmacology; Phenylalanine; Research; Tryptophan

1964
[5-HYDROXYTRYPTOPHAN DOPA DECARBOXYLASE IN NERVOUS AND CARDIAC TISSUES IN THE MOLLUSC HELIX POMATIA. INTERACTION OF SUBSTRATES IN VITRO].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1964, Jul-27, Volume: 259

    Topics: 5-Hydroxytryptophan; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; Dopa Decarboxylase; Heart; In Vitro Techniques; Methyldopa; Mollusca; Myocardium; Nerve Tissue; Physiology, Comparative; Research; Serotonin; Tryptophan; Tyrosine

1964
EFFECT OF METHYLDOPA ON THE METABOLISM OF CATECHOLAMINES AND TRYPTOPHAN IN METASTATIC PHEOCHROMOCYTOMA; REPORT OF TWO CASES.
    The American journal of cardiology, 1964, Volume: 14

    Topics: Blood; Blood Pressure; Blood Pressure Determination; Catecholamines; Humans; Hypertension; Metabolism; Methyldopa; Pheochromocytoma; Toxicology; Tryptophan; Urine

1964
[ALPHA,BETA,BETA-TRIMETHYLDOPA, A NEW INHIBITOR OF TRYPTOPHAN AND PHENYLALANINE HYDROXYLASE].
    Helvetica physiologica et pharmacologica acta, 1964, Volume: 64

    Topics: Amides; Amino Acids; Enzyme Inhibitors; Liver; Methyldopa; Mixed Function Oxygenases; Norepinephrine; Pharmacology; Phenylalanine; Phenylalanine Hydroxylase; Rats; Research; Serotonin; Tryptophan

1964
EFFECT OF DRUGS ON THE LEVELS OF INDOLE AND PHENOLIC ACIDS IN THE CENTRAL NERVOUS SYSTEM.
    International journal of neuropharmacology, 1964, Volume: 3

    Topics: Brain; Dopamine; Hydroxybenzoates; Hydroxyindoleacetic Acid; Indoleacetic Acids; Metabolism; Methyldopa; Pharmacology; Phenylacetates; Rabbits; Research; Reserpine; Serotonin; Tryptophan

1964
INFLUENCE OF METHYL-DOPA ON TRYPTOPHAN-LOADING TESTS IN HYPERTENSIVE PATIENTS.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 154

    Topics: Carboxy-Lyases; Drug Therapy; Enzyme Inhibitors; Hypertension; Indoles; Methyldopa; Tryptamines; Tryptophan; Urine

1965