tryptophan has been researched along with macimorelin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 11 (50.00) | 24.3611 |
| 2020's | 6 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Arvat, E; Benso, A; Boeglin, D; Boutignon, F; Broglio, F; Catapano, F; Deghenghi, R; Fehrentz, JA; Ghè, C; Ghigo, E; Gottero, C; Guerlavais, V; Locatelli, V; Martinez, J; Muccioli, G; Prodam, F; Torsello, A | 1 |
| Boeglin, D; Catapano, F; Deghenghi, R; Fehrentz, JA; Galleyrand, JC; Ghé, C; Guerlavais, V; Heitz, A; Locatelli, V; Martinez, J; Mousseaux, D; Muccioli, G; Oiry, C; Torsello, A | 1 |
| Broglio, F; Deghenghi, R; Ghigo, E; Muccioli, G; Papotti, M | 1 |
| Baselgia, L; Beglinger, C; Degen, L; Drewe, J; Larsen, F; MacLean, C; Peter, S; Piccoli, F | 1 |
| Baselgia-Jeker, L; Beglinger, C; Casanova, AT; Drewe, J; Larsen, F; MacLean, CM; Neave, N; Skillern, L | 1 |
| Carmignac, D; Escobar, P; Fehrentz, JA; Fontanaud, P; Gouty-Colomer, LA; Guerineau, NC; Martinez, J; Méry, PF; Mitutsova, V; Molino, F; Mollard, P; Osterstock, G; Robinson, IC | 1 |
| Dieci, E; Ferrucci, F; Mrak, E; Pagani, F; Sibilia, V; Tulipano, G | 1 |
| Biller, BM; Bonert, V; Cook, D; Dobs, A; Garcia, JM; Kipnes, M; Kyle, M; Merriam, GR; Molitch, ME; Swerdloff, R; Wang, C; Yuen, KC | 1 |
| Demianová, Z; Drápalová, J; Fehrentz, JA; Haluzík, M; Holubová, M; Jurčovičová, J; Lacinová, Z; Maletínská, L; Martinez, J; Spolcová, A; Stofková, A; Sýkora, D; Zelezná, B | 1 |
| Biagini, G; Bresciani, E; Curia, G; Gualtieri, F; Locatelli, V; Lucchi, C; Torsello, A; Vinet, J | 1 |
| Casati, L; Celotti, F; Dieci, E; Pagani, F; Sibilia, V | 1 |
| Agrawal, V; Garcia, JM | 1 |
| Aicher, B; Banères, JL; Blayo, AL; Damian, M; Denoyelle, S; Fehrentz, JA; Gagne, D; Günther, E; M'Kadmi, C; Maingot, M; Marie, J; Martinez, J; Mary, S; Müller, G; Sanchez, P; Schmidt, P; Teifel, M | 1 |
| Aourz, N; Coppens, J; De Bundel, D; Fehrentz, JA; Martinez, J; Portelli, J; Smolders, I; Walrave, L | 1 |
| Ammer, N; Biller, BMK; Blevins, T; Bolanowski, M; Chanson, P; Garcia, JM; Korbonits, M; Luger, A; Marcelli, M; Medic-Stojanoska, M; Pekic, S; Popovic, V; Sachse, R; Schopohl, J; Strasburger, CJ; Swerdloff, R; Wang, C; Yuen, KCJ; Zakrzewska, A | 1 |
| Ben Haj Salah, K; Buckinx, A; Cottone, E; De Bundel, D; Fehrentz, JA; Kooijman, R; Pierre, A; Smolders, I; Van Den Herrewegen, Y | 1 |
| Ammer, N; Demmel, V; Kelepouris, N; Lissy, M; Ostrow, V; Sachse, R | 1 |
| Bidlingmaier, M; Delahaut, P; Fichant, E; Görgens, C; Lange, T; Schilbach, K; Thevis, M; Thomas, A | 1 |
| Ammer, N; Christ-Crain, M; Drummond, JR; Lustenberger, S; Ribeiro-Oliveira, A; Soares, BS; Urwyler, SA; Vogt, DR; Yuen, KCJ | 1 |
| Buckinx, A; De Bundel, D; Gerlach, M; Guenther, E; Kooijman, R; Pierre, A; Smolders, I; Van Den Herrewegen, Y; Van Laethem, G | 1 |
| Chifu, I; Christ-Crain, M; Eckert, A; Fassnacht, M; Fenske, W; Lawson, EA; Refardt, J; Sailer, CO; Schnyder, I; Urwyler, SA; Varghese, N; Verbalis, JG; Winzeler, B | 1 |
| Ammer, N; Bagci, EB; Bolshova, OV; Chaychenko, T; Csákváry, V; Damholt, BB; Katanic, D; Mikhailova, E; Muzsnai, Á; Raduk, D; Senatorova, G; Szalecki, M; Teifel, M; Vajda, Z; Zelinska, N | 1 |
2 review(s) available for tryptophan and macimorelin
| Article | Year |
|---|---|
Targeting the ghrelin receptor: orally active GHS and cortistatin analogs.
Topics: Animals; Energy Metabolism; Growth Hormone; Human Growth Hormone; Humans; Indoles; Ligands; Neuropeptides; Oligopeptides; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Tryptophan | 2003 |
The macimorelin-stimulated growth hormone test for adult growth hormone deficiency diagnosis.
Topics: Adult; Diagnostic Techniques, Endocrine; Ghrelin; Human Growth Hormone; Humans; Indoles; Tryptophan | 2014 |
4 trial(s) available for tryptophan and macimorelin
| Article | Year |
|---|---|
Pharmacokinetics and pharmacodynamic effects of an oral ghrelin agonist in healthy subjects.
Topics: Administration, Oral; Adult; Area Under Curve; Dose-Response Relationship, Drug; Duodenum; Ghrelin; Growth Hormone-Releasing Hormone; Half-Life; Hormones; Human Growth Hormone; Humans; Indoles; Intubation, Gastrointestinal; Male; Oligopeptides; Peptide Hormones; Tryptophan | 2007 |
Effect of food on the pharmacokinetics and pharmacodynamics of an oral ghrelin agonist (ARD-07) in healthy subjects.
Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Food-Drug Interactions; Ghrelin; Human Growth Hormone; Humans; Indoles; Insulin-Like Growth Factor I; Male; Oligopeptides; Tryptophan | 2009 |
Macimorelin as a Diagnostic Test for Adult GH Deficiency.
Topics: Administration, Oral; Adolescent; Adult; Age of Onset; Aged; Cross-Over Studies; Diagnostic Tests, Routine; Female; Human Growth Hormone; Humans; Hypopituitarism; Indoles; Male; Middle Aged; Pituitary Function Tests; Reproducibility of Results; Sensitivity and Specificity; Tryptophan; Young Adult | 2018 |
Thorough QT/QTc Study Evaluating the Effect of Macimorelin on Cardiac Safety Parameters in Healthy Participants.
Topics: Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Indoles; Long QT Syndrome; Male; Middle Aged; Moxifloxacin; Tryptophan; Young Adult | 2021 |
16 other study(ies) available for tryptophan and macimorelin
| Article | Year |
|---|---|
EP1572: a novel peptido-mimetic GH secretagogue with potent and selective GH-releasing activity in man.
Topics: Adult; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Ghrelin; Growth Hormone; Human Growth Hormone; Humans; Indoles; Male; Oligopeptides; Peptide Hormones; Pituitary Gland; Rats; Tryptophan | 2002 |
New active series of growth hormone secretagogues.
Topics: Administration, Oral; Adult; Animals; Animals, Newborn; Binding, Competitive; Cell Line; Dogs; Female; Growth Hormone; Humans; In Vitro Techniques; Indoles; Injections, Subcutaneous; Male; Membranes; Middle Aged; Oligopeptides; Pituitary Gland; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Tryptophan | 2003 |
Ghrelin stimulation of growth hormone-releasing hormone neurons is direct in the arcuate nucleus.
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Estrenes; Female; Ghrelin; Green Fluorescent Proteins; Growth Hormone-Releasing Hormone; Indoles; Male; Mice; Mice, Transgenic; Neurons; Oligopeptides; Patch-Clamp Techniques; Pyrrolidinones; Receptors, Ghrelin; Tryptophan; Type C Phospholipases | 2010 |
Pharmacological characterization of the ghrelin receptor mediating its inhibitory action on inflammatory pain in rats.
Topics: Animals; Carrageenan; Edema; Ghrelin; Hyperalgesia; Indoles; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Male; Oligopeptides; Pain; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Ghrelin; Tryptophan | 2012 |
Macimorelin (AEZS-130)-stimulated growth hormone (GH) test: validation of a novel oral stimulation test for the diagnosis of adult GH deficiency.
Topics: Administration, Oral; Adult; Aged; Arginine; Cross-Over Studies; Female; Ghrelin; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Indoles; Insulin-Like Growth Factor I; Male; Middle Aged; ROC Curve; Tryptophan | 2013 |
Ghrelin agonist JMV 1843 increases food intake, body weight and expression of orexigenic neuropeptides in mice.
Topics: Adipose Tissue, Brown; Agouti-Related Protein; Animals; Appetite Stimulants; Dose-Response Relationship, Drug; Eating; Ghrelin; Hypothalamus; Indoles; Injections, Subcutaneous; Ion Channels; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Neuropeptide Y; Oligopeptides; Receptors, Ghrelin; RNA, Messenger; Signal Transduction; Tryptophan; Uncoupling Protein 1; Up-Regulation; Weight Gain | 2013 |
Protective but not anticonvulsant effects of ghrelin and JMV-1843 in the pilocarpine model of Status epilepticus.
Topics: Animals; Corpus Striatum; Endothelin-1; Gene Expression Regulation; Ghrelin; Glial Fibrillary Acidic Protein; Indoles; Male; Muscarinic Agonists; Oligopeptides; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Tryptophan | 2013 |
Acylated and unacylated ghrelin protect MC3T3-E1 cells against tert-butyl hydroperoxide-induced oxidative injury: pharmacological characterization of ghrelin receptor and possible epigenetic involvement.
Topics: Actin Cytoskeleton; Acylation; Animals; Apoptosis; Cell Line; Dose-Response Relationship, Drug; Epigenesis, Genetic; Ghrelin; Histones; Indoles; Mice; Oligopeptides; Osteoblasts; Oxidative Stress; Protective Agents; Reactive Oxygen Species; Receptors, Ghrelin; tert-Butylhydroperoxide; Tryptophan | 2014 |
New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center.
Topics: Fluorescence Resonance Energy Transfer; Indoles; Inhibitory Concentration 50; Ligands; Receptors, Ghrelin; Structure-Activity Relationship; Substance P; Triazoles; Tryptophan | 2016 |
Anticonvulsant effect of a ghrelin receptor agonist in 6Hz corneally kindled mice.
Topics: Animals; Anticonvulsants; Cornea; Disease Models, Animal; Electric Stimulation; Glycine; Indoles; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligopeptides; Receptors, Ghrelin; Status Epilepticus; Triazoles; Tryptophan | 2016 |
Differential Effects of a Full and Biased Ghrelin Receptor Agonist in a Mouse Kindling Model.
Topics: Animals; Benzazepines; beta-Arrestins; Brain; Dopamine Agonists; Glycine; Indoles; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Piperidines; Quinazolinones; Receptors, Ghrelin; Triazoles; Tryptophan | 2019 |
Comprehensive insights into the formation of metabolites of the ghrelin mimetics capromorelin, macimorelin and tabimorelin as potential markers for doping control purposes.
Topics: Animals; Biomarkers; Chromatography, Liquid; Dipeptides; Doping in Sports; Female; Ghrelin; Humans; Indoles; Limit of Detection; Male; Piperidines; Pyrazoles; Rats; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptophan | 2021 |
Effects of oral macimorelin on copeptin and anterior pituitary hormones in healthy volunteers.
Topics: Adrenocorticotropic Hormone; Diabetes Insipidus; Diagnostic Tests, Routine; Glycopeptides; Healthy Volunteers; Humans; Indoles; Pituitary Hormones; Prolactin; Prospective Studies; Tryptophan | 2021 |
Translational potential of the ghrelin receptor agonist macimorelin for seizure suppression in pharmacoresistant epilepsy.
Topics: Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus; Humans; Indoles; Mice; Mice, Inbred C57BL; Receptors, Ghrelin; Seizures; Status Epilepticus; Tryptophan | 2021 |
Oxytocin levels in response to pituitary provocation tests in healthy volunteers.
Topics: Adult; Arginine; Female; Humans; Indoles; Male; Oxytocin; Pituitary Gland; Saline Solution, Hypertonic; Tryptophan; Young Adult | 2021 |
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Macimorelin in Children with Suspected Growth Hormone Deficiency: An Open-Label, Group Comparison, Dose-Escalation Trial.
Topics: Child; Dose-Response Relationship, Drug; Female; Ghrelin; Growth Hormone; Humans; Indoles; Male; Pediatrics; Reproducibility of Results; Surveys and Questionnaires; Tryptophan | 2021 |