tryptophan has been researched along with levodopa in 138 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 91 (65.94) | 18.7374 |
| 1990's | 10 (7.25) | 18.2507 |
| 2000's | 17 (12.32) | 29.6817 |
| 2010's | 18 (13.04) | 24.3611 |
| 2020's | 2 (1.45) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H | 1 |
| Parkkila, AK; Parkkila, S; Puccetti, L; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Innocenti, A; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Innocenti, A; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Innocenti, A; Kaila, K; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Nishimori, I; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Ferry, JG; Innocenti, A; Scozzafava, A; Supuran, CT; Zimmerman, SA | 1 |
| Arslan, O; Aydin, M; Guler, OO; Innocenti, A; Isik, S; Kockar, F; Scozzafava, A; Supuran, CT | 1 |
| Hilvo, M; Innocenti, A; Parkkila, S; Scozzafava, A; Supuran, CT | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Hall, RA; Innocenti, A; Mühlschlegel, FA; Scozzafava, A; Supuran, CT | 1 |
| Innocenti, A; Leewattanapasuk, W; Manole, G; Mühlschlegel, FA; Scozzafava, A; Supuran, CT | 1 |
| Bertucci, A; Supuran, CT; Tambutté, S; Vullo, D; Zoccola, D | 1 |
| Capasso, C; Carginale, V; De Luca, V; Rossi, M; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Akdemir, A; Capasso, C; Carginale, V; De Luca, V; Rossi, M; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Capasso, C; Del Prete, S; Supuran, CT; Vullo, D | 1 |
| AlOthman, Z; Capasso, C; Del Prete, S; Donald, WA; Osman, SM; Supuran, CT; Vullo, D | 1 |
| Evans, JP; Grahame-Smith, DG; Green, AR; Tordoff, AF | 1 |
| Daniel, PM; Moorhouse, SR; Pratt, OE | 1 |
| Boullin, DJ; Grahame-Smith, DG; Green, AR; Heal, DJ | 1 |
| Murphy, DL | 1 |
| Lane, JD; McBride, WJ; Shea, PA; Smith, JE | 1 |
| Mobin, A; Rosengren, E; Simert, G; Vang, J | 1 |
| Allikmets, LH; Zharkovsky, AM | 1 |
| Daniel, PM; Moorhouse, RS; Pratt, OE | 1 |
| Bouyer, JJ; Dedet, L; Joseph, JP; Rougeul, A | 1 |
| Luchins, D | 1 |
| Bäck, N; Partanen, S; Rechardt, L | 1 |
| Bunney, WE; Kopanda, RT; Murphy, DL | 1 |
| Franz, DN; Hare, BD; Neumayr, RJ | 1 |
| Wirz-Justice, A | 1 |
| Partanen, S | 3 |
| Aksenova, IO | 1 |
| MacMillan, V | 1 |
| Zieve, L | 1 |
| Bender, DA; Earl, CJ; Lees, AJ | 1 |
| Kohno, Y; Matsuo, K; Nagasaki, N; Takeda, S; Tanaka, M | 1 |
| Chadwick, D; Driver, MV; Jenner, P; Reynolds, EH; Trimble, M | 1 |
| Deakin, JF; Green, AR | 1 |
| Carlsson, A | 1 |
| Altshuler, HL; Killam, EK; Killam, KF | 1 |
| Breese, GR; Cooper, BR; Cott, JM; Jahnke, GD; Lipton, MA; Plotnikoff, NP; Prange, AJ; Wilson, IC | 1 |
| Grahame-Smith, DG; Green, AR; Heal, DJ; Kelly, PH | 1 |
| Barchas, JD; Watson, SJ | 1 |
| Moore, KE; Wuerthele, SM | 1 |
| Green, AR; Mitchell, BD; Tordoff, AF; Youdim, MB | 1 |
| Askenazi, JJ; Rabey, JM; Streifler, M; Vardi, J | 1 |
| Feigenson, JS; Goodell, H; Loranger, AW; McDowell, FH; Sweet, RD | 1 |
| Diez, JA; Summer, GK; Ward, WG | 1 |
| Kehr, W | 1 |
| Tissot, R | 1 |
| Allikmets, LKh; Zharkovskiĭ, AM | 1 |
| De Léan, J; Hornykiewicz, O; Richardson, JC | 1 |
| Dunner, DL; Fieve, RR | 1 |
| Burns, D; Frazer, A; Mendels, J; Stinnett, JL | 1 |
| Birkmayer, W; Danielczyk, W; Neumayer, E; Riederer, P | 1 |
| Fahn, S; Lane, E; Makadon, H; Prasad, AL; Snider, S | 1 |
| Campanelli, C; Campriani, S; Cozzolino, G | 1 |
| George, CF; Macklin, B; Renwick, AG; Usman, F; Waller, DG | 1 |
| Meltzer, HY; Parsa, MA; Ramirez, LF; Rohr, T | 1 |
| Byerley, WF; Risch, SC | 1 |
| Carlsson, A; Eriksson, T; Wiesel, K | 1 |
| Ericsson, K; Forssell, LG; Hellström, A; Winblad, B | 1 |
| Hayashi, T; Nakane, A; Naruse, H; Takesada, M; Yamazaki, K | 1 |
| Borisenko, SA | 1 |
| Fisher, H; Sandyk, R | 1 |
| Dichgans, J; Scholz, E | 1 |
| Leathwood, PD | 1 |
| Schnaberth, G | 1 |
| Atterwill, CK; Brown, CG; Collins, P | 1 |
| Birkmayer, W | 1 |
| Berman, ML; Tennant, F | 1 |
| Harvey, NS | 1 |
| Contreras, E; Germany, A; Merino, A | 1 |
| Cobasko, D; Dement, WC; Guilleminault, C; Mancuso, J; Mondini, S; Montplaisir, J | 1 |
| Demling, J | 1 |
| Bermejo Pareja, F; de Yébenes, JG; Martinez-Martin, P; Muradas, V | 1 |
| Jacobs, BL | 1 |
| Garelis, E; Lal, S; Sourkes, TL; Young, SN | 1 |
| Dunner, DL | 1 |
| Williams, R | 1 |
| Carlsson, A; Eriksson, T; Hagman, M; Jagenburg, R | 1 |
| Buxton, DA; Friend, J; Kent, AP | 1 |
| Nuller, JL; Ostroumova, MN | 1 |
| Brammer, GL; Hershman, JM; Morley, JE; Sharp, B; Yamada, T; Yuwiler, A | 1 |
| Balsara, JJ; Chandorkar, AG; Gada, VP; Nandal, NV | 1 |
| James, VA; Wigham, T | 1 |
| Kohno, Y | 1 |
| Watanabe, Y | 1 |
| Franz, DN; Sangdee, C | 1 |
| Kent, S | 1 |
| Stern, L; Tenenhouse, A; Yu, EW | 1 |
| Blagoeva, PM | 1 |
| Baldessarini, RJ | 1 |
| Gelenberg, AJ | 1 |
| Koulu, M; Lammintausta, R | 1 |
| Carlsson, A; Eriksson, T | 1 |
| Gelber, LR; Neumeyer, JL | 1 |
| Lehmann, J | 1 |
| Riederer, P | 1 |
| Crawford, RD; Jaju, AT; Johnson, DD; Ness, L; Richardson, JS | 1 |
| Fahn, S; Floud, A | 1 |
| Berezhnaia, VA; Nuller, IuL; Ostroumova, MN | 1 |
| Korányi, L; Phelps, CP; Tamásy, V | 1 |
| Beasley, BL; Chase, TN; Davenport, RW; Nutt, JG | 1 |
| Anisimov, VN | 1 |
| Kaakkola, S; Kask, A; Männistö, PT; Törnwall, M; Tuomainen, P | 1 |
| Aubineau, P; Callebert, J; Decreme, C; Issertial, O; Mathiau, P; Reynier-Rebuffel, AM | 1 |
| Block, F; Clement, HW; Grote, C; Sontag, KH; Wesemann, W | 1 |
| Hashiguti, H; Ikeda, T; Maruyama, W; Nakahara, D; Naoi, M | 1 |
| Hesselink, JM | 1 |
| Achilli, G; Banting, A; Banting, S; Le Bars, D; Weil-Fugazza, J | 1 |
| Allikmets, L; Matto, V; Skrebuhhova, T | 1 |
| Camp, DM; DeMaggio, AJ; Havaich, MK; Juneau, PL; LeWitt, PA; Loeffler, DA; Matson, WR; Milbury, PE | 1 |
| Catania, C; Cestelli, A; D'Agostino, S; De Caro, V; Di Liegro, I; Giandalia, G; Giannola, LI; Licata, L; Pitarresi, GL; Savettieri, G; Schiera, G | 1 |
| Ipe, BI; Mahima, S; Thomas, KG | 1 |
| Campiglia, P; Gomez-Monterrey, I; Grieco, P; Lama, T; Novellino, E | 1 |
| Driguès, N; Sagi, Y; Youdim, MB | 1 |
| Miller, EM; Nieburg, HA | 1 |
| Rodgers, KJ; Shiozawa, N | 1 |
| Kincses, ZT; Szabó, N; Toldi, J; Vécsei, L | 1 |
| Krzyściak, W | 1 |
| Boskovic, R; Clark, M; Houle, S; Kish, SJ; Meyer, JH; Rabiner, EA; Rusjan, P; Sacher, J; Soliman, A; Wilson, AA | 1 |
| Baker, H; Morgan, LD; Patel, BA; Yeoman, MS | 1 |
| Alcaraz, MR; Araújo, MC; Goicoechea, HC; Gomes, Ade A | 1 |
| Bezard, E; Ko, WK; Li, Q | 1 |
| Corrigan, F; Hassall, MM; Thornton, E; Vink, R | 1 |
| Macedo, CR; Macedo, EC; Prado, GF; Silva, AB; Torloni, MR | 1 |
| Eskow Jaunarajs, KL; Figge, DA; Standaert, DG | 1 |
| Chen, G; He, Y; Liu, S; Liu, Z; Wei, N; You, J; Zhao, XE; Zheng, L; Zhu, S | 1 |
| Guan, B; Liu, Z; Lu, X; Pan, X | 1 |
| Asakawa, T; Chen, W; Jia, X; Qin, W; Shi, Y | 1 |
15 review(s) available for tryptophan and levodopa
| Article | Year |
|---|---|
The behavioral toxicity of monoamine oxidase-inhibiting antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior; Behavior, Animal; Dextroamphetamine; Humans; Hydrazines; Iproniazid; Isocarboxazid; Levodopa; Lithium; Monoamine Oxidase Inhibitors; Nialamide; Pargyline; Phenelzine; Procarbazine; Rats; Tranylcypromine; Tryptophan | 1977 |
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain Chemistry; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Fenclonine; Fusaric Acid; Humans; Levodopa; Lithium; Methyldopa; Methyltyrosines; Methysergide; Monoamine Oxidase Inhibitors; Phenylketonurias; Reserpine; Tryptophan | 1976 |
Carbonyl compound-induced fluorescence of biogenic monoamines in the endocrine cells of the hypophysis.
Topics: 5-Hydroxytryptophan; Acetates; Animals; Biogenic Amines; Catecholamines; Chemical Phenomena; Chemistry; Chloral Hydrate; Endorphins; Female; Fluorescence; Formaldehyde; Glyoxylates; Histamine; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Ninhydrin; Ozone; Peptides; Pituitary Gland, Anterior; Pregnancy; Serotonin; Tryptamines; Tryptophan | 1978 |
[Therapeutically resistant depressive states].
Topics: Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depersonalization; Depression; Drug Resistance; Electroconvulsive Therapy; Half-Life; Humans; Hypochondriasis; Levodopa; Middle Aged; Monoamine Oxidase Inhibitors; Sleep Deprivation; Syndrome; Thyrotropin; Tryptophan | 1979 |
Hepatic encephalopathy: summary of present knowledge with an elaboration on recent developments.
Topics: Amino Acids; Ammonia; Animals; Brain Chemistry; Dogs; Hepatic Encephalopathy; Humans; Levodopa; Rats; Tryptophan | 1979 |
Monoamine precursors and analogues.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Drug Interactions; Drug Synergism; Humans; Levodopa; Mice; Parkinson Disease; Rats; Receptors, Drug; Stimulation, Chemical; Tremor; Tryptophan; Tyrosine | 1975 |
Depression and serotonin metabolism: rationale for neurotransmitter precursor treatment.
Topics: 5-Hydroxytryptophan; Antidepressive Agents, Tricyclic; Blood Platelets; Brain Chemistry; Depressive Disorder; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Levodopa; Male; Neurotransmitter Agents; Norepinephrine; Receptors, Neurotransmitter; Serotonin; Thyrotropin; Thyrotropin-Releasing Hormone; Tryptophan | 1985 |
Psychiatric disorders in parkinsonism. 1. Functional illnesses and personality.
Topics: Antidepressive Agents; Clozapine; Depressive Disorder; Dopamine; Electroconvulsive Therapy; Female; Homovanillic Acid; Humans; Levodopa; Male; Mental Disorders; Nomifensine; Nortriptyline; Parkinson Disease; Personality; Psychotic Disorders; Serotonin; Tryptophan | 1986 |
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.
Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroid Plexus; Dihydroxyphenylalanine; Dogs; Dopamine; Fenclonine; Glycols; Haplorhini; Homovanillic Acid; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Probenecid; Serotonin; Spinal Cord; Spinal Cord Injuries; Tryptophan | 1974 |
Fulminant viral hepatitis.
Topics: Acute Disease; Acute Kidney Injury; Amino Acids; Ammonia; Animals; Brain; Brain Diseases; Brain Edema; Cross Circulation; Female; Hemorrhagic Disorders; Heparin; Hepatic Encephalopathy; Hepatitis A; Humans; Levodopa; Liver Regeneration; Prothrombin Time; Swine; Tryptophan | 1974 |
Misincorporation of amino acid analogues into proteins by biosynthesis.
Topics: Amino Acids; Amino Acids, Diamino; Aminoacylation; Animals; Bacteria; Canavanine; Ethionine; Humans; Levodopa; Lupus Erythematosus, Systemic; Oxidation-Reduction; Parkinson Disease; Plants; Protein Biosynthesis; Tryptophan | 2008 |
Altered tryptophan metabolism in Parkinson's disease: a possible novel therapeutic approach.
Topics: Antiparkinson Agents; Humans; Kynurenine; Levodopa; Parkinson Disease; Tryptophan | 2011 |
Activity of selected aromatic amino acids in biological systems.
Topics: Biomarkers; Cardiovascular Diseases; Enzyme Activation; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Levodopa; Melanins; Monophenol Monooxygenase; Nervous System Diseases; Oxidative Stress; Renal Insufficiency, Chronic; Serotonin; Tryptophan; Tyrosine | 2011 |
Pharmacotherapy for sleep bruxism.
Topics: Amitriptyline; Bromocriptine; Clonidine; Humans; Levodopa; Propranolol; Randomized Controlled Trials as Topic; Sleep Bruxism; Tryptophan | 2014 |
Can kynurenine pathway be considered as a next-generation therapeutic target for Parkinson's disease? An update information.
Topics: 3-Hydroxyanthranilic Acid; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Levodopa; Parkinson Disease; Quinolinic Acid; Tryptophan | 2022 |
10 trial(s) available for tryptophan and levodopa
| Article | Year |
|---|---|
Biogenic amines and affective disorders. A critical analysis.
Topics: 5-Hydroxytryptophan; Affective Symptoms; Antidepressive Agents, Tricyclic; Biogenic Amines; Bipolar Disorder; Brain Chemistry; Clinical Trials as Topic; Depression; Electroconvulsive Therapy; Fenclonine; Fusaric Acid; Humans; Levodopa; Lithium; Methyldopa; Methyltyrosines; Methysergide; Monoamine Oxidase Inhibitors; Phenylketonurias; Reserpine; Tryptophan | 1976 |
Manipulation of cerebral monoamines in the treatment of human epilepsy: a pilot study.
Topics: Adult; Biogenic Amines; Brain Chemistry; Carbamazepine; Drug Evaluation; Epilepsy; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Monoamine Oxidase Inhibitors; Pilot Projects; Serotonin; Tryptophan | 1978 |
Mental symptoms in Parkinson's disease during chronic treatment with levodopa.
Topics: Adult; Aged; Delirium; Dementia; Female; Humans; Levodopa; Male; Mental Disorders; Middle Aged; Parkinson Disease; Parkinson Disease, Postencephalitic; Tryptophan | 1976 |
Affective disorder: studies with amine precursors.
Topics: Adult; Antidepressive Agents; Biogenic Amines; Bipolar Disorder; Brain; Brain Chemistry; Clinical Trials as Topic; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Models, Biological; Placebos; Remission, Spontaneous; Tryptophan | 1975 |
Amine precursors and depression.
Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Depression; Humans; Levodopa; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Recurrence; Tryptophan | 1975 |
Oral amino acids and gastric emptying: an investigation of the mechanism of levodopa-induced gastric stasis.
Topics: Acetaminophen; Administration, Oral; Adult; Chromatography, High Pressure Liquid; Female; Gastric Emptying; Glycine; Humans; Levodopa; Male; Tryptophan | 1991 |
Early stages of late onset Alzheimer's disease. Diagnostic criteria, protein metabolism, precursor loading effects, neurochemical and neuropsychological applications.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Choline; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Levodopa; Male; Nerve Tissue Proteins; Neuropsychological Tests; Neurotransmitter Agents; Phosphatidylcholines; Tryptophan | 1989 |
[Metabolic changes in aromatic amino acids and monoamines in infantile autism and development of new treatment related to the finding].
Topics: 5-Hydroxytryptophan; Amino Acids; Autistic Disorder; Biogenic Monoamines; Biopterins; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Deuterium; Double-Blind Method; Humans; Levodopa; Phenylalanine; Tryptophan | 1989 |
L-tryptophan in the treatment of levodopa induced psychiatric disorders.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Brain; Female; Humans; Levodopa; Male; Mental Disorders; Middle Aged; Parkinson Disease; Serotonin; Single-Blind Method; Treatment Outcome; Tryptophan | 1974 |
Dynamic, adaptive changes in MAO-A binding after alterations in substrate availability: an in vivo [(11)C]-harmine positron emission tomography study.
Topics: Carbidopa; Carbon Radioisotopes; Corpus Striatum; Dopamine; Dopamine Agonists; Drug Combinations; Harmine; Humans; Levodopa; Monoamine Oxidase; Parkinson Disease; Positron-Emission Tomography; Prefrontal Cortex; Protein Binding; Serotonin; Substrate Specificity; Time Factors; Tryptophan | 2012 |
114 other study(ies) available for tryptophan and levodopa
| Article | Year |
|---|---|
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis | 2002 |
Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.
Topics: Amines; Amino Acids; Carbonic Anhydrases; Enzyme Activators; Isoenzymes | 2006 |
Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines.
Topics: Amines; Amino Acids; Carbonic Anhydrases; Catalysis; Enzyme Activation; Humans; Kinetics; Mitochondrial Proteins; Protein Isoforms; Structure-Activity Relationship | 2007 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.
Topics: Amines; Amino Acid Sequence; Amino Acids; Carbonic Anhydrases; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Molecular Sequence Data; Protein Isoforms; Protein Subunits | 2007 |
Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines.
Topics: Amines; Amino Acid Sequence; Amino Acids; Carbonic Anhydrases; Enzyme Activation; Enzyme Activators; Humans; Isoenzymes; Molecular Sequence Data; Sequence Homology, Amino Acid | 2007 |
Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.
Topics: Amines; Amino Acids; Antigens, Neoplasm; Carbonic Anhydrase IX; Carbonic Anhydrases; Conserved Sequence; Enzyme Activation; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Molecular Structure; Neoplasms; Sequence Alignment; Structure-Activity Relationship | 2008 |
Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines.
Topics: Amines; Amino Acids; Binding Sites; Carbonic Anhydrase III; Carbonic Anhydrase IV; Cell Membrane; Cytosol; Enzyme Activation; Histidine; Humans; Isoenzymes; Molecular Structure; Morpholines; Serotonin; Stereoisomerism | 2008 |
Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines.
Topics: Amines; Amino Acids; Archaea; Carbonic Anhydrases; Catalysis; Molecular Structure; Phenylalanine; Stereoisomerism; Tyrosine | 2008 |
Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids.
Topics: Amino Acids; Candida albicans; Carbonic Anhydrases; Catalysis; Catalytic Domain; Cryptococcus neoformans; Drug Design; Enzyme Activation; Epinephrine; Humans; Kinetics; Models, Chemical; Protein Isoforms; Saccharomyces cerevisiae; Tryptophan | 2009 |
Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines.
Topics: Amines; Amino Acid Sequence; Amino Acids; Animals; Carbonic Anhydrases; Enzyme Activators; Humans; Kinetics; Mice; Molecular Sequence Data; Protein Isoforms; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids.
Topics: Amines; Amino Acids; Candida albicans; Carbonic Anhydrase I; Carbonic Anhydrases; Cryptococcus neoformans; Enzyme Activation; Structure-Activity Relationship | 2010 |
Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids.
Topics: Amines; Amino Acids; Candida glabrata; Carbonic Anhydrases; Catalytic Domain; Enzyme Activation; Humans; Kinetics; Models, Molecular; Recombinant Proteins; Structure-Activity Relationship | 2010 |
Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines.
Topics: Amines; Amino Acids; Animals; Anthozoa; Carbonic Anhydrases; Enzyme Activation; Humans; Isoenzymes; Kinetics; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2010 |
The first activation study of a bacterial carbonic anhydrase (CA). The thermostable α-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines.
Topics: Amines; Amino Acids; Carbon Dioxide; Carbonic Anhydrases; Enzyme Activation; Gram-Negative Chemolithotrophic Bacteria; Kinetics | 2012 |
The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines.
Topics: Amines; Amino Acids; Bacteria; Carbonic Anhydrases; Catalysis; Structure-Activity Relationship; Sulfur Compounds | 2013 |
Carbonic anhydrase activators: Activation of the β-carbonic anhydrase from Malassezia globosa with amines and amino acids.
Topics: Amines; Amino Acids; Antifungal Agents; Carbonic Anhydrases; Dandruff; Dose-Response Relationship, Drug; Ligands; Malassezia; Molecular Structure; Structure-Activity Relationship | 2016 |
Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines.
Topics: Amines; Amino Acids; Burkholderia pseudomallei; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship | 2017 |
Electroconvulsive shock increases the behavioural responses of rats to brain 5-hydroxytryptamine accumulation and central nervous system stimulant drugs.
Topics: Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Hydroxyindoleacetic Acid; Levodopa; Male; Motor Activity; Pentylenetetrazole; Rats; Serotonin; Stimulation, Chemical; Time Factors; Tranylcypromine; Tryptophan | 1976 |
Amino acid precursors of monoamine neurotransmitters and some factors influencing their supply to the brain.
Topics: Amino Acids, Essential; Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Carbon Radioisotopes; Histidine; Levodopa; Neurotransmitter Agents; Osmolar Concentration; Phenylalanine; Protein Precursors; Rats; Tryptophan; Tyrosine | 1976 |
Single and repeated administration of neuroleptic drugs to rats: effects on striatal dopamine-sensitive adenylate cyclase and locomotor activity produced by tranylcypromine and L-tryptophan or L-Dopa.
Topics: Adenylyl Cyclase Inhibitors; Animals; Antipsychotic Agents; Corpus Striatum; Dopamine; Levodopa; Male; Motor Activity; Rats; Receptors, Dopamine; Serotonin; Tranylcypromine; Tryptophan | 1976 |
Neurochemical changes following the administration of precursors of biogenic amines.
Topics: 5-Hydroxytryptophan; Acetylcholine; Amino Acids; Animals; Brain; Choline; Dopamine; gamma-Aminobutyric Acid; Levodopa; Male; Neurotransmitter Agents; Norepinephrine; Rats; Serotonin; Tryptophan; Tyrosine | 1977 |
Neurotransmittor changes in the rat brain after portacaval anastomosis.
Topics: Animals; Blood Proteins; Brain; Dopamine; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Levodopa; Male; Neurotransmitter Agents; Norepinephrine; Portacaval Shunt, Surgical; Rats; Serotonin; Tryptophan | 1978 |
Biochemical and behavioural studies on the interference between catecholaminergic and serotonergic central systems.
Topics: Adrenergic alpha-Agonists; Amphetamine; Animals; Apomorphine; Behavior, Animal; Brain; Dopamine; Exploratory Behavior; Levodopa; Male; Motor Activity; Rats; Serotonin; Tryptophan | 1978 |
Letter: Do changes in blood levels of other aromatic aminoacids influence levodopa therapy?
Topics: Amino Acids; Blood-Brain Barrier; Histidine; Humans; Levodopa; Parkinson Disease; Phenylalanine; Tryptophan | 1976 |
Modification of spontaneous ECoG and behavior in cat by monoamine precursors.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Biogenic Amines; Cats; Electroencephalography; Levodopa; Sleep; Tryptophan; Tyrosine | 1979 |
Histochemical observations on uptake of L-dopa into endocrine cells of the rat pituitary gland during the postnatal development.
Topics: Adrenocorticotropic Hormone; Age Factors; Animals; Female; Fluorescence; Formaldehyde; Growth Hormone; Histocytochemistry; Levodopa; Peptides; Pituitary Gland; Pituitary Gland, Anterior; Rats; Serotonin; Tryptophan | 1975 |
Sleep and behavioral changes possibly reflecting central receptor hypersensitivity following catecholamine synthesis inhibition in man.
Topics: Behavior; Bipolar Disorder; Dopamine; Humans; Levodopa; Norepinephrine; Receptors, Neurotransmitter; Sleep; Substance Withdrawal Syndrome; Tryptophan; Tyrosine | 1977 |
L-dopa-induced hypotension: depression of spinal sympathetic neurons by release of 5-hydroxytryptamine.
Topics: 5-Hydroxytryptophan; Animals; Autonomic Fibers, Preganglionic; Blood Pressure; Cats; Levodopa; Medulla Oblongata; Neural Inhibition; Reflex; Serotonin; Spinal Cord; Sympathetic Nervous System; Synaptic Transmission; Tryptophan | 1977 |
Theoretical and therapeutic potential of indolamine precursors in affective disorders.
Topics: 5-Hydroxytryptophan; Amino Acids; Bipolar Disorder; Depression; Emotions; Female; Humans; Levodopa; Male; Phenylalanine; Serotonin; Sex Factors; Tryptophan; Tyrosine | 1977 |
The effects of the anticonvulsant valproic acid on cerebral indole amine metabolism.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dopamine; Female; Hydroxyindoleacetic Acid; Indoles; Levodopa; Rats; Serotonin; Tryptophan; Valproic Acid | 1979 |
Niacin depletion in Parkinsonian patients treated with L-dopa, benserazide and carbidopa.
Topics: Adolescent; Adult; Benserazide; Bromocriptine; Carbidopa; Female; Humans; Hydrazines; Levodopa; Male; Micrococcus; Middle Aged; Nicotinamidase; Nicotinic Acids; Parkinson Disease; Tryptophan | 1979 |
Quenching effects of various compounds on fluorometric assay of tryptophan.
Topics: Animals; Catecholamines; Fluorometry; Levodopa; Male; Rats; Serotonin; Tryptophan | 1979 |
The effects of putative 5-hydroxytryptamine antagonists on the behaviour produced by administration of tranylcypromine and L-tryptophan or tranylcypromine and L-DOPA to rats.
Topics: Animals; Behavior, Animal; Brain; Drug Interactions; Levodopa; Male; Methyltyrosines; p-Chloroamphetamine; Propranolol; Rats; Serotonin; Serotonin Antagonists; Spinal Cord; Tranylcypromine; Tryptamines; Tryptophan | 1978 |
Biogenic amines and the photomyoclonic syndrome in the baboon, Papio papio.
Topics: Animals; Biogenic Amines; Dopamine; Epinephrine; Evoked Potentials; Female; Haplorhini; Injections, Intraventricular; Levodopa; Male; Myoclonus; Norepinephrine; Papio; Photic Stimulation; Reserpine; Serotonin; Tryptophan | 1976 |
Parameters of alteration of pentobarbital response by hypothalamic polypeptides.
Topics: Amphetamine; Animals; Dose-Response Relationship, Drug; Drug Interactions; Levodopa; Male; Mice; Pentobarbital; Somatostatin; Temperature; Thyrotropin-Releasing Hormone; Tryptophan | 1975 |
The contrasting actions of TRH and cycloheximide in altering the effects of centrally acting drugs: evidence for the non-involvement of dopamine sensitive adenylate cyclase.
Topics: Adenylyl Cyclases; Amphetamines; Animals; Apomorphine; Caudate Nucleus; Cycloheximide; Dopamine; Drug Interactions; Hydroxydopamines; In Vitro Techniques; Levodopa; Male; Methamphetamine; Motor Activity; Norepinephrine; Pentylenetetrazole; Poly I-C; Rats; Receptors, Dopamine; Sleep; Thyrotropin-Releasing Hormone; Tranylcypromine; Tryptophan | 1976 |
Catecholamine histofluorescence using cryostat sectioning and glyoxylic acid in unperfused frozen brain: a detailed description of the technique.
Topics: Animals; Axons; Brain Chemistry; Dopamine; Fluorescence; Frozen Sections; Glyoxylates; Histocytochemistry; Levodopa; Male; Norepinephrine; Rats; Reserpine; Serotonin; Tryptophan | 1977 |
Studies on the mechanisms of L-dopa-induced depletion of 5-hydroxytryptamine in the mouse brain.
Topics: Amines; Animals; Benztropine; Biological Transport; Brain; Clomipramine; Cocaine; Dihydroxyphenylalanine; Dopamine; Imipramine; Levodopa; Male; Mice; Mice, Inbred ICR; Serotonin; Tryptophan | 1977 |
Evidence for dopamine deamination by both type A and type B monoamine oxidase in rat brain in vivo and for the degree of inhibition of enzyme necessary for increased functional activity of dopamine and 5-hydroxytryptamine.
Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Clorgyline; Deamination; Dopamine; Drug Interactions; Levodopa; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Motor Activity; Norepinephrine; Rats; Serotonin; Time Factors; Tranylcypromine; Tryptophan | 1977 |
L-tryptophan administration in L-dopa-induced hallucinations in elderly Parkinsonian patients.
Topics: Aged; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Tryptophan | 1977 |
Tryptophan transport in brain synaptosomes: effects of L-DOPA.
Topics: Animals; Biological Transport, Active; Brain; Depression, Chemical; Levodopa; Male; Mice; Synaptosomes; Tryptophan | 1976 |
Fluorescence histochemical observations on the uptake and metabolism of tryptophan in the endocrine cells of the hypophysis.
Topics: 5-Hydroxytryptophan; Animals; Female; Histocytochemistry; Levodopa; Male; Microscopy, Fluorescence; Pituitary Gland; Rats; Tryptophan | 1975 |
Influence of L-3-methoxytyrosine on monoamine synthesis in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Liver; Male; Myocardium; Norepinephrine; Rats; Serotonin; Tryptophan; Tyrosine | 1975 |
[Hypothetical concept: the physiopathological entity of monoaminergic psychoses].
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Behavior, Animal; Bipolar Disorder; Blood-Brain Barrier; Catecholamines; Diet; Humans; Levodopa; Neurons; Rats; Schizophrenia; Serotonin; Sexual Behavior; Tryptophan; Tyrosine | 1975 |
[The influence of 1-DOPA on emotional responses and serotonin metabolism in the rat brain].
Topics: 5-Hydroxytryptophan; Aggression; Animals; Brain; Dopamine; Emotions; Exploratory Behavior; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Orientation; Rats; Serotonin; Stimulation, Chemical; Tryptophan | 1976 |
Beneficial effects of serotonin precursors in postanoxic action myoclonus.
Topics: 5-Hydroxytryptophan; Aged; Carbidopa; Female; Humans; Hydroxyindoleacetic Acid; Hypoxia; Levodopa; Male; Methysergide; Middle Aged; Myoclonus; Serotonin; Syndrome; Tryptophan | 1976 |
Dopaminergic supersensitivity in parkinsonism.
Topics: Aged; Benzyl Compounds; Brain; Brain Chemistry; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Nerve Degeneration; Norepinephrine; Parkinson Disease; Psychoses, Substance-Induced; Serotonin; Tryptophan; Tyrosine | 1975 |
Normalization of brain serotonin by L-tryptophan in levodopa-treated rats.
Topics: Animals; Behavior, Animal; Brain; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Drug Therapy, Combination; Homovanillic Acid; Levodopa; Male; Rats; Serotonin; Tryptophan | 1975 |
Simultaneous fluorescence histochemical demonstration of catecholamines and tryptophyl-peptides in endocrine cells.
Topics: Acetates; Animals; Catecholamines; Chloral Hydrate; Dopamine; Female; Formaldehyde; Freeze Drying; Glyoxylates; Histocytochemistry; Levodopa; Male; Microscopy, Fluorescence; Peptides; Pituitary Gland; Pituitary Gland, Anterior; Rats; Serotonin; Tryptophan; Volatilization | 1975 |
Tryptophan/nicotinic acid pathway during levodopa treatment of Parkinsonism.
Topics: Adult; Aged; Female; Humans; Levodopa; Male; Middle Aged; Nicotinic Acids; Parkinson Disease; Tryptophan | 1975 |
Neuroleptic malignant syndrome without neuroleptics.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Depressive Disorder; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome; Tranylcypromine; Tryptophan | 1990 |
Rat brain concentration of administered amino acids: dependence on time of day for administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Brain Chemistry; Dihydroxyphenylalanine; Drug Administration Schedule; Hydroxyindoleacetic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Serotonin; Time Factors; Tryptophan | 1986 |
[Effect of ethanol and probenecid on the excretory function of the cerebral choroid plexus in rats].
Topics: Animals; Carbon Radioisotopes; Choroid Plexus; Dose-Response Relationship, Drug; Ethanol; Levodopa; Male; Probenecid; Rats; Rats, Inbred Strains; Time Factors; Tryptophan; Tyrosine | 1989 |
L-tryptophan supplementation in Parkinson's disease.
Topics: Aged; Drug Therapy, Combination; Female; Humans; Levodopa; Middle Aged; Parkinson Disease; Tryptophan | 1989 |
Treatment of drug-induced exogenous psychosis in parkinsonism with clozapine and fluperlapine.
Topics: Aged; Antipsychotic Agents; Benserazide; Bromocriptine; Clozapine; Delusions; Dibenzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hallucinations; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced; Tryptophan | 1985 |
Neurotransmitter precursors and brain function.
Topics: Aged; Aging; Alzheimer Disease; Animals; Biological Transport; Brain; Diet; Humans; Learning; Levodopa; Memory; Neurotransmitter Agents; Parkinson Disease; Phosphatidylcholines; Serotonin; Sleep; Tryptophan | 1986 |
[Depression and Parkinson syndrome].
Topics: Antidepressive Agents; Brain; Depressive Disorder; Drug Therapy, Combination; Humans; Levodopa; Neurotransmitter Agents; Parkinson Disease; Tryptophan | 1986 |
Studies on the effect of chronic L-triiodothyronine (T3) treatment on brain Na+,K+-ATPase activity in the mature rat.
Topics: Animals; Brain; Female; Hypothalamus; Levodopa; Male; Mathematics; Pituitary Gland; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Thyrotropin; Thyrotropin-Releasing Hormone; Tissue Distribution; Triiodothyronine; Tryptophan | 1987 |
Milestones in the development of modern Parkinson therapy.
Topics: 2,3-Diketogulonic Acid; Alloxan; Behavior; Bromocriptine; Drug Combinations; Drug Therapy, Combination; Ferric Compounds; Humans; Levodopa; Neurology; Parkinson Disease; Selegiline; Tryptophan | 1987 |
Stepwise detoxification from cocaine. A promising regimen.
Topics: Adolescent; Adult; Amantadine; Bromocriptine; Cocaine; Desipramine; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine | 1988 |
Serotonergic and adrenergic mechanisms in tolerance development to ethanol and barbital.
Topics: Animals; Barbital; Barbiturates; Drug Tolerance; Ethanol; Fenfluramine; Levodopa; Male; Mice; Norepinephrine; Phenoxybenzamine; Serotonin; Sleep; Tryptophan | 1987 |
Periodic leg movement, L-dopa, 5-hydroxytryptophan, and L-tryptophan.
Topics: Aged; Female; Humans; Leg; Levodopa; Male; Middle Aged; Motor Activity; Periodicity; Restless Legs Syndrome; Serotonin; Sleep; Tryptophan | 1987 |
[L-dopa-induced psychoses and their treatment with L-tryptophan].
Topics: Humans; Levodopa; Parkinson Disease; Psychoses, Substance-Induced; Tryptophan | 1986 |
Carbidopa dosage modifies L-dopa induced side effects and blood levels of L-dopa and other amino acids in advanced parkinsonism.
Topics: Aged; Carbidopa; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Kinetics; Levodopa; Male; Middle Aged; Parkinson Disease; Tryptophan; Tyrosine | 1985 |
Evidence for the functional interaction of two central neurotransmitters.
Topics: Anilides; Animals; Behavior, Animal; Cinnamates; Dopamine; Dopamine Antagonists; Drug Interactions; Fenclonine; Levodopa; Male; Methyltyrosines; Methysergide; Muscle Rigidity; Neurotransmitter Agents; Pargyline; Pimozide; Rats; Serotonin; Serotonin Antagonists; Sulfides; Synaptic Transmission; Tremor; Tryptophan | 1974 |
[Malignant melanoma and L-dopa. Review of literature on the problem of causal relationship].
Topics: Humans; Levodopa; Male; Melanins; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Parkinson Disease; Skin Neoplasms; Tryptophan | 1974 |
Proceedings: Amine precursors in depression: studies combining L-DOPA and L-tryptophan.
Topics: Animals; Depression; Humans; Levodopa; Tryptophan | 1974 |
Beta-adrenergic influence on brain concentrations of monoamine precursors.
Topics: Amino Acids; Animals; Brain Chemistry; Epinephrine; Isoproterenol; Levodopa; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tryptophan; Tyrosine | 1984 |
Beta-adrenoceptor antagonists in L-tryptophan and L-DOPA induced behavioural syndromes [proceedings].
Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Drug Interactions; Levodopa; Male; Rats; Tryptophan | 1980 |
Resistance to inhibiting effect of dexamethasone in patients with endogenous depression.
Topics: 11-Hydroxycorticosteroids; Adolescent; Adult; Aged; Anti-Anxiety Agents; Corticotropin-Releasing Hormone; Depression; Dexamethasone; Diazepam; Drug Synergism; Female; Humans; Levodopa; Male; Middle Aged; Serotonin; Tryptophan | 1980 |
Neurotransmitter control of hypothalamic-pituitary-thyroid function in rats.
Topics: Animals; Hypothalamo-Hypophyseal System; Levodopa; Lithium; Male; Neurotransmitter Agents; Rats; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine; Tryptophan | 1981 |
Psychopharmacological investigation of the monoamine oxidase inhibitory activity of molindone, a dihydroindolone neuroleptic.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Behavior, Animal; Blepharoptosis; Catalepsy; Fenclonine; Fenfluramine; Humans; Indoles; Levodopa; Male; Mice; Molindone; Monoamine Oxidase Inhibitors; p-Chloroamphetamine; Rats; Reserpine; Stereotyped Behavior; Tryptamines; Tryptophan | 1984 |
Evidence for dopaminergic and serotonergic regulation of prolactin cell activity in the trout Salmo gairdneri.
Topics: 5-Hydroxytryptophan; Animals; Domperidone; Dopamine; Fenclonine; Levodopa; Pituitary Gland; Prolactin; Salmonidae; Serotonin; Somatostatin; Thyrotropin-Releasing Hormone; Trout; Tryptophan | 1984 |
[Effect of L-DOPA on brain serotonin metabolism related to tryptophan concentrations in plasma and brain of rats].
Topics: Animals; Benserazide; Brain; Brain Chemistry; Dopamine; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Levodopa; Male; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1981 |
[Interactions of cerebral serotonin and catecholamines].
Topics: 5,7-Dihydroxytryptamine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain; Catecholamines; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Nerve Endings; Neurons; Norepinephrine; Rats; Serotonin; Tryptophan | 1983 |
Lithium enhancement of central 5-HT transmission induced by 5-HT precursors.
Topics: 5-Hydroxytryptophan; Animals; Autonomic Fibers, Preganglionic; Cats; Dose-Response Relationship, Drug; Evoked Potentials; Intercostal Nerves; Levodopa; Lithium; Medulla Oblongata; Neural Pathways; Norepinephrine; Reflex; Serotonin; Spinal Cord; Synaptic Transmission; Tryptophan | 1980 |
Drugs to boost sexual potency.
Topics: Aged; Animals; Aphrodisiacs; Female; Fenclonine; Gonadotropin-Releasing Hormone; Humans; Levodopa; Male; Middle Aged; Rats; Sexual Behavior; Sexual Behavior, Animal; Tryptophan | 1981 |
Decarboxylation of L-dopa and 5-hydroxytryptophan in dispersed rat pancreas acinar cells.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Binding, Competitive; Decarboxylation; Female; Histidine; In Vitro Techniques; Levodopa; Pancreas; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tyrosine | 1984 |
Aminoacids--precursors of melanin synthesis in hamster melanoma.
Topics: Amino Acids; Animals; Cricetinae; Ferrous Compounds; Iron; Levodopa; Male; Melanins; Melanoma; Mesocricetus; Neoplasm Transplantation; Phenylalanine; Tryptophan; Tyrosine | 1984 |
Treatment of depression by altering monoamine metabolism: precursors and metabolic inhibitors.
Topics: Biogenic Amines; Catecholamines; Depression; Humans; Levodopa; Monoamine Oxidase Inhibitors; Serotonin; Tryptophan; Tyrosine | 1984 |
New antidepressant drugs: a clinical perspective.
Topics: Antidepressive Agents; Depression; Humans; Levodopa; Tryptophan | 1984 |
Effects of L-deprenyl on human growth hormone secretion.
Topics: Adult; Apomorphine; Growth Hormone; Humans; Kinetics; Levodopa; Male; Phenethylamines; Selegiline; Tryptophan | 1981 |
Isoprenaline increases brain concentrations of administered L-dopa and L-tryptophan in the rat.
Topics: Animals; Brain; Dopamine; Isoproterenol; Levodopa; Male; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine | 1982 |
Determination of the enantiomeric purity of levodopa, methyldopa, carbidopa and tryptophan by use of chiral mobile phase high-performance liquid chromatography.
Topics: Capsules; Carbidopa; Chromatography, High Pressure Liquid; Copper; Copper Sulfate; Drug Contamination; Levodopa; Methyldopa; Phenylalanine; Stereoisomerism; Tablets; Tryptophan | 1983 |
Tryptophan deficiency stupor--a new psychiatric syndrome.
Topics: Aged; Animals; Carcinoid Tumor; Female; Humans; Levodopa; Malabsorption Syndromes; Male; Mental Disorders; Middle Aged; Muscles; Parkinson Disease; Serotonin; Syndrome; Tryptophan | 1982 |
L-dopa competes with tyrosine and tryptophan for human brain uptake.
Topics: Aged; Benserazide; Blood-Brain Barrier; Brain; Female; Humans; Levodopa; Male; Parkinson Disease; Tryptophan; Tyrosine | 1980 |
Brain norepinephrine, dopamine, and 5-hydroxytryptamine concentration abnormalities and their role in the high seizure susceptibility of epileptic chickens.
Topics: Animals; Biogenic Amines; Brain Chemistry; Chickens; Dopamine; Epilepsy; Levodopa; Norepinephrine; Phenelzine; Poultry Diseases; Serotonin; Tryptophan | 1981 |
L-DOPA (L-3,4-dihydroxyphenylalanine) uptake by human red blood cells.
Topics: Biological Transport; Cell Membrane Permeability; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Leucine; Levodopa; Tryptophan | 1981 |
[Various factors common to the pathogenesis of endogenous depression and chronic alcoholism].
Topics: 11-Hydroxycorticosteroids; Adolescent; Adult; Aged; Alcoholism; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Depressive Disorder; Dexamethasone; Female; Humans; Levodopa; Male; Mental Disorders; Middle Aged; Tryptophan | 1981 |
The role of dopaminergic and serotonergic mechanisms in the development of swimming ability of young rats.
Topics: Age Factors; Amphetamine; Animals; Animals, Newborn; Apomorphine; Haloperidol; Hydroxydopamines; Levodopa; Methysergide; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Swimming; Tryptophan | 1981 |
Treatment with tryptophan of levodopa-associated psychiatric disturbances.
Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Psychoses, Substance-Induced; Tryptophan | 1980 |
Study on serotoninergic mechanisms of compensatory ovarian hypertrophy in rats.
Topics: Animals; Brain; Castration; Diethylstilbestrol; Female; Hypertrophy; Indoles; Levodopa; Melatonin; Morpholines; Ovary; Pineal Gland; Pyridazines; Rats; Serotonin; Tryptophan | 1980 |
Comparison of two new inhibitors of catechol O-methylation on striatal dopamine metabolism: a microdialysis study in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amidines; Animals; Biogenic Monoamines; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Microdialysis; Neostriatum; Nitriles; Pyridones; Rats; Rats, Wistar; Stereotaxic Techniques; Tryptophan; Tyrosine | 1994 |
Absence of serotonergic innervation from raphe nuclei in rat cerebral blood vessels--II. Lack of tryptophan hydroxylase activity in vitro.
Topics: 5-Hydroxytryptophan; Animals; Brain; Cerebral Cortex; Cerebrovascular Circulation; Femoral Artery; Hydroxyindoleacetic Acid; In Vitro Techniques; Levodopa; Male; Nerve Fibers; Norepinephrine; Pineal Gland; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1993 |
Functional studies on monoaminergic transmitter release in parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Apomorphine; Biogenic Monoamines; Dopamine; Dopamine Agents; Dopamine Antagonists; Hydroxyindoleacetic Acid; Levodopa; Male; Monoamine Oxidase Inhibitors; Parkinson Disease, Secondary; Rats; Rats, Wistar; Stereotyped Behavior; Tryptophan | 1993 |
Simultaneous determination of in vivo hydroxylation of tyrosine and tryptophan in rat striatum by microdialysis-HPLC: relationship between dopamine and serotonin biosynthesis.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Homovanillic Acid; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Kinetics; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 1993 |
Serotonin and Parkinson's disease.
Topics: Basal Ganglia Diseases; Depressive Disorder; Dopamine; Drug Therapy, Combination; Fluoxetine; Humans; Levodopa; Parkinson Disease; Serotonin; Tryptophan | 1993 |
Tyrosine and tryptophan derivatives in pig lumbar cerebrospinal fluid. Effects of subchronic administration of dopa associated with benserazide.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Benserazide; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Kynurenine; Levodopa; Male; Methoxyhydroxyphenylglycol; Normetanephrine; Swine; Tryptamines; Tryptophan; Tyrosine | 1996 |
The effect of antidepressants on rat aggressive behavior in the electric footshock and apomorphine-induced aggressiveness paradigms.
Topics: Aggression; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Apomorphine; Citalopram; Desipramine; Dopamine Agents; Electroshock; Fluoxetine; Levodopa; Male; Pain Measurement; Rats; Rats, Wistar; Tryptophan | 1998 |
Influence of repeated levodopa administration on rabbit striatal serotonin metabolism, and comparison between striatal and CSF alterations.
Topics: 5-Hydroxytryptophan; Animals; Corpus Striatum; Hydroxyindoleacetic Acid; Levodopa; Male; Rabbits; Serotonin; Tryptophan | 1998 |
Functional feature of a novel model of blood brain barrier: studies on permeation of test compounds.
Topics: Animals; Blood-Brain Barrier; Cells, Cultured; Dopamine; Levodopa; Permeability; Rats; Rats, Sprague-Dawley; Tryptophan | 2001 |
Light-induced modulation of self-assembly on spiropyran-capped gold nanoparticles: a potential system for the controlled release of amino acid derivatives.
Topics: Amino Acids; Benzopyrans; Delayed-Action Preparations; Gold; Indoles; Levodopa; Light; Nitro Compounds; Particle Size; Photochemistry; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2003 |
A new efficient synthetic methodology for tetrahydroisoquinoline and tetrahydro-beta-carboline derivatives using the Pictet-Spengler reaction.
Topics: Carbolines; Combinatorial Chemistry Techniques; Dopamine; Levodopa; Magnetic Resonance Spectroscopy; Microwaves; Models, Chemical; Tetrahydroisoquinolines; Time Factors; Tryptophan | 2004 |
The neurochemical and behavioral effects of the novel cholinesterase-monoamine oxidase inhibitor, ladostigil, in response to L-dopa and L-tryptophan, in rats.
Topics: Animals; Basal Ganglia; Behavior, Animal; Carbamates; Cholinesterase Inhibitors; Dopamine; Hippocampus; Hyperkinesis; Indans; Levodopa; Lewy Body Disease; Male; Monoamine Oxidase Inhibitors; Motor Activity; Muscarinic Antagonists; Norepinephrine; Phenylcarbamates; Rats; Rats, Sprague-Dawley; Rivastigmine; Scopolamine; Serotonin; Time Factors; Tranylcypromine; Tryptophan | 2005 |
Chromatographic assay to study the activity of multiple enzymes involved in the synthesis and metabolism of dopamine and serotonin.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Animals; Biological Assay; Central Nervous System; Chromatography; Dopamine; Dopamine Agents; Hydroxyindoleacetic Acid; Levodopa; Lymnaea; Models, Biological; Molecular Structure; Serotonin; Tryptophan; Tyrosine | 2012 |
The Successive Projections Algorithm for interval selection in trilinear partial least-squares with residual bilinearization.
Topics: Algorithms; Chromatography, High Pressure Liquid; Ciprofloxacin; Fluoroquinolones; Hydroquinones; Least-Squares Analysis; Levodopa; Ofloxacin; Phenylalanine; Software; Spectrophotometry, Ultraviolet; Tryptophan; Water | 2014 |
Effects of L-tryptophan on L-DOPA-induced dyskinesia in the L-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Motor Activity; Parkinson Disease; Tryptophan | 2014 |
The NK1 receptor antagonist N-acetyl-L-tryptophan reduces dyskinesia in a hemi-parkinsonian rodent model.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Antiparkinson Agents; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Functional Laterality; Levodopa; Male; Medial Forebrain Bundle; Motor Activity; Oxidopamine; Parkinsonian Disorders; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Time Factors; Tryptophan; Tyrosine 3-Monooxygenase | 2014 |
Dynamic DNA Methylation Regulates Levodopa-Induced Dyskinesia.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Corpus Striatum; Dioxygenases; Disease Models, Animal; DNA Methylation; Dopamine; Dyskinesia, Drug-Induced; Enzyme Inhibitors; GADD45 Proteins; Gene Expression Regulation; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Phthalimides; Rats; Rats, Sprague-Dawley; Tryptophan | 2016 |
Determination of dopamine, serotonin, biosynthesis precursors and metabolites in rat brain microdialysates by ultrasonic-assisted in situ derivatization-dispersive liquid-liquid microextraction coupled with UHPLC-MS/MS.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dopamine; Dyskinesias; Epinephrine; Hydroxyindoleacetic Acid; Levodopa; Liquid Phase Microextraction; Male; Norepinephrine; Rats, Sprague-Dawley; Rhodamines; Serotonin; Tandem Mass Spectrometry; Tryptophan; Ultrasonics | 2016 |
Design, synthesis and cytotoxicity of novel hexacyclic saframycin-ecteinascidin analogs.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Line, Tumor; Cytotoxins; Drug Design; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Isoquinolines; Levodopa; Structure-Activity Relationship; Tryptophan | 2020 |