tryptophan and guanosine 5'-o-(3-thiotriphosphate)

tryptophan has been researched along with guanosine 5'-o-(3-thiotriphosphate) in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (55.56)18.2507
2000's7 (38.89)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gilman, AG; Lee, E; Taussig, R1
Ferguson, KM; Higashijima, T1
Pan, JY; Sanford, JC; Wessling-Resnick, M2
Cerione, RA1
Chabre, M; Chardin, P; Faurobert, E; Otto-Bruc, A1
Antonny, B; Chabre, M; Chardin, P; Otto-Bruc, A; Vuong, TM1
Hamm, HE; Mazzoni, MR1
Lan, KL; Neubig, RR; Remmers, AE1
Matalon, R; Warner, DR; Weinstein, LS; Weng, G; Yu, S1
Cummings, D; Jesaitis, AJ; Miettinen, HM; Mills, JS1
Begg, G; Freymann, DM; Graham, RM; Iismaa, S; Lorand, L; Murthy, SN1
Jones, K; Jones, KA; Perkins, WJ; Streiff, J; Warner, DO1
Baltazar, C; Brodbeck, RM; Chenard, BL; Currie, K; Hutchison, AJ; Krause, JE; Maynard, G; Peck, AE; Severance, D; Steflik, J; Waters, SM; Yu, J; Zhang, LY1
Hamm, HE; Liao, G; Meier, SM; Parello, J; Preininger, AM1
Chouchana, L; Hamon, M; Hanoun, N; Kelaï, S; Lanfumey, L; Renoir, T; Saurini, F1
Hamm, HE; Liao, G; Meier, SM; Preininger, AM1
Cowell, S; Davis, P; Hruby, VJ; Kulkarni, V; Lai, J; Ma, SW; Moye, S; Nair, P; Navratilova, E; Porreca, F; Vanderah, TW; Yamamoto, T1

Other Studies

18 other study(ies) available for tryptophan and guanosine 5'-o-(3-thiotriphosphate)

ArticleYear
The G226A mutant of Gs alpha highlights the requirement for dissociation of G protein subunits.
    The Journal of biological chemistry, 1992, Jan-15, Volume: 267, Issue:2

    Topics: Adenylyl Cyclases; Animals; Base Sequence; Brain; Cattle; Chromatography, Gel; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Fluorescence; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Magnesium; Molecular Sequence Data; Mutation; Protein Conformation; Substrate Specificity; Trypsin; Tryptophan

1992
Tryptophan fluorescence of G proteins: analysis of guanine nucleotide binding and hydrolysis.
    Methods in enzymology, 1991, Volume: 195

    Topics: Animals; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hydrolysis; Indicators and Reagents; Kinetics; Protein Binding; Spectrometry, Fluorescence; Tryptophan

1991
Effect of guanine nucleotide binding on the intrinsic tryptophan fluorescence properties of Rab5.
    The Journal of biological chemistry, 1995, Oct-13, Volume: 270, Issue:41

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Bromosuccinimide; Cholic Acids; Detergents; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oxidation-Reduction; Point Mutation; Protein Binding; rab5 GTP-Binding Proteins; Recombinant Proteins; Spectrometry, Fluorescence; Tryptophan

1995
Fluorescence assays for G-protein interactions.
    Methods in enzymology, 1994, Volume: 237

    Topics: Animals; Chromatography, Gel; Fluorescent Dyes; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Indicators and Reagents; Kinetics; Macromolecular Substances; Receptors, Cell Surface; Rhodopsin; Spectrometry, Fluorescence; Tryptophan; Vertebrates

1994
Tryptophan W207 in transducin T alpha is the fluorescence sensor of the G protein activation switch and is involved in the effector binding.
    The EMBO journal, 1993, Volume: 12, Issue:11

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aluminum Compounds; Amino Acid Sequence; Animals; Baculoviridae; DNA Mutational Analysis; Enzyme Activation; Fluorescence; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Models, Molecular; Molecular Sequence Data; Moths; Protein Conformation; Recombinant Proteins; Rod Cell Outer Segment; Sequence Homology, Amino Acid; Signal Transduction; Transducin; Tryptophan

1993
Interaction between the retinal cyclic GMP phosphodiesterase inhibitor and transducin. Kinetics and affinity studies.
    Biochemistry, 1993, Aug-24, Volume: 32, Issue:33

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cattle; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Macromolecular Substances; Mathematics; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Recombinant Proteins; Restriction Mapping; Retina; Rod Cell Outer Segment; Transducin; Tryptophan

1993
Tryptophan207 is involved in the GTP-dependent conformational switch in the alpha subunit of the G protein transducin: chymotryptic digestion patterns of the GTP gamma S and GDP-bound forms.
    Journal of protein chemistry, 1993, Volume: 12, Issue:2

    Topics: Amino Acid Sequence; Animals; Cattle; Chymotrypsin; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Molecular Sequence Data; Peptide Fragments; Protein Conformation; Transducin; Tryptophan

1993
Influence of Mg2+ on the structure and function of Rab5.
    The Journal of biological chemistry, 1996, Jan-19, Volume: 271, Issue:3

    Topics: Amino Acid Sequence; Base Sequence; DNA Primers; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Point Mutation; Polymerase Chain Reaction; rab5 GTP-Binding Proteins; Recombinant Proteins; Sequence Deletion; Spectrometry, Fluorescence; Trypsin; Tryptophan

1996
Roles of G(o)alpha tryptophans in GTP hydrolysis, GDP release, and fluorescence signals.
    Biochemistry, 1998, Jan-20, Volume: 37, Issue:3

    Topics: Amino Acid Substitution; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; ortho-Aminobenzoates; Phenylalanine; Polymerase Chain Reaction; Spectrometry, Fluorescence; Tryptophan

1998
A novel mutation in the switch 3 region of Gsalpha in a patient with Albright hereditary osteodystrophy impairs GDP binding and receptor activation.
    The Journal of biological chemistry, 1998, Sep-11, Volume: 273, Issue:37

    Topics: Adenylyl Cyclases; Adult; Alanine; Aluminum Compounds; Amino Acid Sequence; Arginine; Base Sequence; Binding Sites; Cloning, Molecular; Erythrocyte Membrane; Escherichia coli; Exons; Female; Fibrous Dysplasia, Polyostotic; Fluorides; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Male; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Polymerase Chain Reaction; Protein Biosynthesis; Protein Structure, Secondary; Receptors, Cell Surface; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Tryptophan

1998
Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu.
    The Journal of biological chemistry, 2000, Dec-15, Volume: 275, Issue:50

    Topics: Alanine; Animals; Anti-HIV Agents; Arginine; Asparagine; Aspartic Acid; Binding Sites; Chemotaxis; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enfuvirtide; Guanosine 5'-O-(3-Thiotriphosphate); HIV Envelope Protein gp41; Humans; Kinetics; Leucine; Ligands; Methionine; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Peptide Biosynthesis; Peptide Fragments; Phenylalanine; Protein Binding; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Sodium; Tryptophan

2000
Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Mar-05, Volume: 99, Issue:5

    Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Conserved Sequence; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Glutamine gamma Glutamyltransferase 2; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Transglutaminases; Tryptophan

2002
Effect of halothane on the guanosine 5' triphosphate binding activity of G-protein alphai subunits.
    Anesthesiology, 2003, Volume: 99, Issue:1

    Topics: Adenosine Triphosphatases; Anesthetics, Inhalation; Blotting, Western; Cell Membrane; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Halothane; Humans; Hydrolysis; Muscle, Smooth; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins; Recombinant Proteins; Suramin; Tryptophan

2003
Molecular characterization of the gerbil C5a receptor and identification of a transmembrane domain V amino acid that is crucial for small molecule antagonist interaction.
    The Journal of biological chemistry, 2005, Dec-09, Volume: 280, Issue:49

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Membrane; Cloning, Molecular; Gene Expression; Gerbillinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptor, Anaphylatoxin C5a; Sequence Alignment; Species Specificity; Structure-Activity Relationship; Tryptophan

2005
Receptor-mediated changes at the myristoylated amino terminus of Galpha(il) proteins.
    Biochemistry, 2008, Sep-30, Volume: 47, Issue:39

    Topics: Detergents; GTP-Binding Protein alpha Subunits; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Models, Molecular; Myristic Acid; Protein Conformation; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Solubility; Surface Properties; Tryptophan

2008
Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice.
    Journal of neurochemistry, 2008, Volume: 107, Issue:6

    Topics: 5-Hydroxytryptophan; Action Potentials; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Body Temperature; Disease Models, Animal; Food Preferences; Guanosine 5'-O-(3-Thiotriphosphate); Hydroxyindoleacetic Acid; Hypothermia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Neurons; Protein Binding; Pyrimidines; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists; Tryptophan

2008
Trp fluorescence reveals an activation-dependent cation-pi interaction in the Switch II region of Galphai proteins.
    Protein science : a publication of the Protein Society, 2009, Volume: 18, Issue:11

    Topics: Arginine; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Kinetics; Models, Molecular; Myristic Acid; Protein Conformation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tryptophan

2009
Discovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activities.
    Bioorganic & medicinal chemistry letters, 2015, Sep-01, Volume: 25, Issue:17

    Topics: Animals; Chemistry Techniques, Synthetic; Drug Discovery; Drug Evaluation, Preclinical; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inhibitory Concentration 50; Ligands; Neurokinin-1 Receptor Antagonists; Peptides; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship; Tryptophan

2015