tryptophan and gamma-aminobutyric acid

tryptophan has been researched along with gamma-aminobutyric acid in 80 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-199040 (50.00)18.7374
1990's10 (12.50)18.2507
2000's8 (10.00)29.6817
2010's12 (15.00)24.3611
2020's10 (12.50)2.80

Authors

AuthorsStudies
Bellman, K; Knegtel, RM; Settimo, L1
Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
BARDAKDJIAN, J; Belin, MF; Gonnard, P; Kouyoumdijian, JC1
Levi, G; Raiteri, M1
Lane, JD; McBride, WJ; Shea, PA; Smith, JE1
Jellinger, K; Kothbauer, P; Riederer, P2
Elbin, J; Randall, W1
Behbehani, AW; Neuhoff, V; Quentin, CD1
Aprison, MH; Lane, JD; McBride, WJ; Shea, PA; Smith, JE1
Vlasov, NA1
Grahame-Smith, DG; Green, AR1
Jellinger, K; Riederer, P1
Biswas, B; Carlsson, A1
Leonard, BE; Ramaekers, F; Rigter, H1
Bloomfield, MR; Green, AR; Tordoff, AF1
Lees, GJ; Weiner, N1
Leonard, BE1
Chen, HY; Lee, EH; Lin, YP1
LeFeuvre, RA; Palou, A; Rothwell, NJ; Serra, F; Slater, D1
Becquet, D; Faudon, M; Hery, F1
Chung, EY; Rosenbaum, D; Van Woert, MH1
Jenner, P; Marsden, CD; Pratt, JA1
Chung, EY; Van Woert, MH1
Meltzer, HL1
Geyer, MA; Lee, EH; Tang, YP; Wang, FB1
Iijima, K1
Battelle, BA; Engbretson, GA1
Barreteau, H; Gayral, P; Jacquot, C; Leroy, JP; Trouvin, JH1
Bushnell, IW; McIntosh, MJ; Moore, MR1
Goodman, SI; Kleinman, JE; Korpi, ER; Wyatt, RJ1
Chaouloff, F; Curzon, G; Kennett, GA; Merino, D; Serrurrier, B1
Bose, M; Mishra, NK1
Farrell, GC; Maddison, JE; Stewart, P; Yau, D1
Maurizi, CP1
Flohé, L; Günzler, WA; Hennies, HH1
Daabees, TT; El-Din, MM; Makar, AB; Zeitoun, R1
Alphs, L; Davis, JM1
Enna, SJ; Fuller, G; Wiggins, RC1
Kennedy, B; Leonard, BE1
Jancsàr, SM; Leonard, BE1
Anderson, GM; Cohen, DJ; Fairbanks, L; Gerner, RH; Hare, TA; Linnoila, M; Scheinin, M; Shaywitz, BA; Young, JG2
Baird-Lambert, JA; Davis, PA; Spence, I; Taylor, KM1
Carmona, E; Gomes, C; Trolin, G1
Ghosh, S; Poddar, MK1
Becquet, D; Deprez, P; Fache, MP; Faudon, M; Francois-Bellan, AM; Giraud, P; Hery, F; Hery, M1
Kanner, BI; Kleinberger-Doron, N1
Baumgartner, M; Bogdan, A; Callebert, J; Deybach, JC; Nordmann, Y; Puy, H; Touitou, Y; Voisin, P1
Baig, SM; Bednar, I; Halawa, A; Parvez, SH; Qureshi, GA1
Cann-Moisan, C; Caroff, J; Girin, E; Giroux, JD; Le Bras, P1
Amin, J1
Adame-González, IG; Beas-Zárate, C; Del Angel-Meza, AR; González Burgos, I; Ramírez-Cortes, L1
Huuhka, M; Keränen, T; Leinonen, E; Oja, SS; Palmio, J; Peltola, J; Saransaari, P; Suhonen, J1
Cowen, PJ; Evans, J; Jezzard, P; Matthews, PM; Selvaraj, S; Wylezinska, M1
Cheng, KC; Connor, JR; Goodman, SI; Housman, C; Jacobs, RE; LaNoue, K; Lazovic, J; O'Callaghan, JP; Simpson, I; Woontner, M; Zinnanti, WJ1
Akk, G; Bracamontes, J; Covey, DF; Li, P; Reichert, DE; Steinbach, JH1
Cheng, Q; Desai, R; Forman, SA; Liu, A; Stewart, D1
Anderson, CM; Edwards, N; Ganapathy, V; Gatfield, KM; Jevons, MP; Thwaites, DT1
Harris, RA; Howard, RJ; Johnson, WD; Trudell, JR1
Barbey, C; Beury-Cirou, A; Burini, JF; Crépin, A; Dufour, A; Faure, D; Feuilloley, M; Hélias, V; Heurlier, K; Latour, X; Nasser, W; Orange, N; Reverchon, S; Taupin, L1
Baumgartner, A; Dohmen, C; Ehrlich, S; Fassbender, C; Haubitz, M; Hoffmann, F; Klingel, R; Köhler, W; Kraft, A; Neumann-Haefelin, T; Schmidt, S; Stich, O; Topka, H1
Elizondo, G; García-Lara, L; González-Esquivel, D; Pérez-Severiano, F; Segovia, J1
Deng, Z; Lei, G; Li, Y; Luo, W; Ren, W; Wu, G; Xiao, W; Zeng, C1
Baker, GB; Li, XM; Rauw, G; Wang, WQ; Zheng, HF1
Cryan, JF; Dinan, TG1
Anuforo, Ó; Bergmann, A; Halldórsson, H; Halldórsson, S; Henriksen, HH; Johansson, PI; McGarrity, S; Palsson, S; Rolfsson, Ó1
Abbott, GW; Manville, RW; Papanikolaou, M1
Gulhar, R; Jialal, I; Shim, K1
Cseh, EK; Klivényi, P; Körtési, T; Nánási, N; Párdutz, Á; Polyák, H; Tajti, J; Vécsei, L; Veres, G; Zádori, D1
Corsi-Zuelli, F; da Roza, DL; Del-Ben, CM; Deminice, R; Fachim, HA; Jordão, AA; Loureiro, CM; Louzada-Junior, P; Menezes, PR; Shuhama, R; Simões-Ambrosio, LMC1
Cai, H; Cao, T; Chen, Q; Jiao, S; Wang, L; Wu, X; Yang, C; Yang, D; Yang, P; Zeng, C; Zhang, S; Zhu, Z1
Fukuda, S; Fukudo, S; Gotoh, Y; Hayashi, T; Kasahara, Y; Kawashima, J; Kurokawa, K; Mori, H; Nakamura, K; Sato, Y; Tanaka, Y; Yamashita, R1
Chen, X; Ge, T; He, Z; Wang, J; Yuan, H; Zhang, L1
Chen, L; Cui, L; Li, G; Liu, D; Qiu, J; Song, X; Sun, Y; Wang, C; Wang, J1
Dietz, KJ; García-Caparrós, P; Kumar, V; Persicke, M; Vogelsang, L; Wirtz, M1
Brito, F; Curcio, HFQ; da Silva Fidalgo, TK1
Maeda, R; Mimura, M; Suematsu, M; Sugiura, Y; Sugiyama, E; Tanaka, KF; Uchida, H; Uchida, T1
Liu, Z; Mu, C; Zhu, W1

Reviews

7 review(s) available for tryptophan and gamma-aminobutyric acid

ArticleYear
Mechanism of action of clonazepam in myoclonus in relation to effects on GABA and 5-HT.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Brain; Clonazepam; Electrophysiology; Fenclonine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Iontophoresis; Myoclonus; Raphe Nuclei; Reserpine; Serotonin; Tryptophan

1986
The neurotoxicology of lead.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Amino Acids; Aminolevulinic Acid; Animals; Biopterins; Brain; Child; Energy Metabolism; gamma-Aminobutyric Acid; Humans; Lead; Lead Poisoning; Nervous System; Norepinephrine; Prospective Studies; Tryptophan; Tyrosine 3-Monooxygenase

1986
Undernutrition and the development of brain neurotransmitter systems.
    Life sciences, 1984, Nov-19, Volume: 35, Issue:21

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Animals, Suckling; Brain; Choline O-Acetyltransferase; Dopamine; Food Deprivation; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Neurotransmitter Agents; Norepinephrine; Nutrition Disorders; Rats; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Dopamine; Receptors, GABA-A; Serotonin; Tissue Distribution; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase; Weaning

1984
Alterations of amino acid metabolism in osteoarthritis: its implications for nutrition and health.
    Amino acids, 2016, Volume: 48, Issue:4

    Topics: Arginine; Creatinine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Homoarginine; Humans; Hydroxyproline; Immunologic Factors; Inflammation; Nutritional Requirements; Nutritional Status; Osteoarthritis; Proline; Tryptophan

2016
Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature.
    Amino acids, 2017, Volume: 49, Issue:1

    Topics: Amino Acids; Autism Spectrum Disorder; Body Fluids; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Glycine; Humans; Serine; Taurine; Tryptophan

2017
The Microbiome-Gut-Brain Axis in Health and Disease.
    Gastroenterology clinics of North America, 2017, Volume: 46, Issue:1

    Topics: Animals; Autistic Disorder; Brain; Cytokines; Depression; Fatty Acids, Volatile; gamma-Aminobutyric Acid; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Irritable Bowel Syndrome; Parkinson Disease; Prebiotics; Probiotics; Tryptophan; Vagus Nerve

2017
Periodontal disease metabolomics signatures from different biofluids: a systematic review.
    Metabolomics : Official journal of the Metabolomic Society, 2022, 10-25, Volume: 18, Issue:11

    Topics: Alanine; Butyrates; Formates; gamma-Aminobutyric Acid; Humans; Lactates; Metabolomics; Mouthwashes; Periodontal Diseases; Periodontitis; Phenylalanine; Propionates; Tryptophan; Tyrosine; Valine

2022

Trials

2 trial(s) available for tryptophan and gamma-aminobutyric acid

ArticleYear
[Treatment of sleep disorders].
    Sovetskaia meditsina, 1977, Issue:12

    Topics: Clinical Trials as Topic; Drug Evaluation; Electrophysiology; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Neurotic Disorders; Psychotherapy; Sleep; Sleep Wake Disorders; Tranquilizing Agents; Tryptophan

1977
Tryptophan depletion does not lower brain GABA levels in healthy volunteers.
    Psychopharmacology, 2006, Volume: 187, Issue:1

    Topics: Adult; Brain Chemistry; Cross-Over Studies; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Serotonin; Tryptophan

2006

Other Studies

71 other study(ies) available for tryptophan and gamma-aminobutyric acid

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
    Genomics, 2002, Volume: 79, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis

2002
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Action of some fluorinated amphetamine-like compounds on the synaptosomal uptake of neurotransmitters.
    Journal of neurochemistry, 1976, Volume: 27, Issue:3

    Topics: Animals; Dopamine; Fenfluramine; gamma-Aminobutyric Acid; Glutamates; In Vitro Techniques; Male; Neurotransmitter Agents; Phenyl Ethers; Propylamines; Rats; Serotonin; Synaptosomes; Tryptophan; Tyrosine

1976
Synaptosomal transport processes.
    International review of neurobiology, 1976, Volume: 19

    Topics: Amino Acids; Animals; Biological Transport, Active; Brain; Calcimycin; Calcium; Choline; Dopamine; gamma-Aminobutyric Acid; Glutamates; Kinetics; Neurotransmitter Agents; Norepinephrine; Ouabain; Sodium; Synaptosomes; Tryptophan

1976
Neurochemical changes following the administration of precursors of biogenic amines.
    Life sciences, 1977, Aug-01, Volume: 21, Issue:3

    Topics: 5-Hydroxytryptophan; Acetylcholine; Amino Acids; Animals; Brain; Choline; Dopamine; gamma-Aminobutyric Acid; Levodopa; Male; Neurotransmitter Agents; Norepinephrine; Rats; Serotonin; Tryptophan; Tyrosine

1977
Changes of some putative neurotransmitters in human cerebral infarction.
    Journal of neural transmission. Supplementum, 1978, Issue:14

    Topics: Aged; Autopsy; Brain; Cerebral Infarction; Dopamine; Female; gamma-Aminobutyric Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neurotransmitter Agents; Serotonin; Spectrometry, Fluorescence; Tryptophan

1978
Serotonin, the superior colliculus, and grooming behavior in cats with neocortical lesions.
    Journal of comparative and physiological psychology, 1977, Volume: 91, Issue:2

    Topics: 5-Hydroxytryptophan; Adrenalectomy; Animals; Cats; Cerebral Cortex; Fenclonine; gamma-Aminobutyric Acid; Grooming; Male; Microinjections; Norepinephrine; Serotonin; Superior Colliculi; Tegmentum Mesencephali; Tryptophan

1977
Neurochemical aspects of post-tetanic potentiation of monosynaptic reflexes in the cat spinal cord. I. Analysis of amino acids at maximum of potentiation.
    Neurobiology, 1975, Volume: 5, Issue:1

    Topics: Action Potentials; Alanine; Amino Acids; Animals; Aspartic Acid; Cats; Electric Stimulation; Female; gamma-Aminobutyric Acid; Glutamine; Glycine; Isoleucine; Leucine; Male; Motor Neurons; Muscle Contraction; Reflex, Monosynaptic; Spinal Cord; Synaptic Transmission; Tryptophan; Tyrosine

1975
A method for concurrent measurement of picomole quantities of acetylcholine, choline, dopamine, norepinephrine, serotonin, 5-hydroxytryptophan, 5-hydroxyindoleacetic acid, tryptophan, tyrosine, glycine, aspartate, glutamate, alanine, and gamma-aminobutyri
    Analytical biochemistry, 1975, Volume: 64, Issue:1

    Topics: 5-Hydroxytryptophan; Acetylcholine; Alanine; Amino Acids; Animals; Aspartic Acid; Brain Chemistry; Choline; Chromatography, Ion Exchange; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glycine; Hydroxyindoleacetic Acid; Male; Methods; Microchemistry; Neurotransmitter Agents; Norepinephrine; Rats; Serotonin; Spectrometry, Fluorescence; Tryptophan; Tyrosine

1975
[The significance of biogenic amines in cerebral infarction (author's transl)].
    Wiener klinische Wochenschrift, 1979, May-11, Volume: 91, Issue:10

    Topics: Aged; Biogenic Amines; Brain; Cerebral Infarction; Dopamine; gamma-Aminobutyric Acid; Humans; Hydroxyindoleacetic Acid; Serotonin; Tryptophan

1979
Processes regulating the functional activity of brain 5-hydroxytryptamine: results of animal experimentation and their relevance to the understanding and treatment of depression.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1978, Volume: 11, Issue:1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Depression; Dopamine; gamma-Aminobutyric Acid; Humans; Monoamine Oxidase; Rats; Serotonin; Tranylcypromine; Tryptophan

1978
Brain monoamines in metabolic coma and stroke.
    Advances in neurology, 1978, Volume: 20

    Topics: Acute Disease; Aged; Biogenic Amines; Brain Chemistry; Coma; Diabetic Coma; Dopamine; Female; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Hydroxyindoleacetic Acid; Intracranial Embolism and Thrombosis; Male; Middle Aged; Serotonin; Time Factors; Tryptophan

1978
The effect of intracerebroventricularly administered GABA on brain monoamine metabolism.
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 299, Issue:1

    Topics: Aminobutyrates; Analysis of Variance; Animals; Brain; Cerebral Ventricles; Dopamine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Male; Norepinephrine; Rats; Tryptophan; Tyrosine

1977
Monamines in brain and urine of rats with hereditary hypothalamic diabetes insipidus.
    Experientia, 1976, Volume: 32, Issue:7

    Topics: Animals; Biogenic Amines; Brain Chemistry; Diabetes Insipidus; Dopamine; gamma-Aminobutyric Acid; Hypothalamus; Male; Norepinephrine; Organ Size; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tyrosine

1976
Elevation of brain GABA concentrations with amino-oxyacetic acid; effect on the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats.
    Journal of neural transmission, 1976, Volume: 39, Issue:1-2

    Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain; Dopamine; gamma-Aminobutyric Acid; Humans; Hyperkinesis; Male; Norepinephrine; Picrotoxin; Rats; Serotonin; Syndrome; Tranylcypromine; Tryptophan

1976
An examination of the catalytic properties of several aminotransferases in brain and liver by means of an improved radiometric assay with dinitrophenylhydrazine.
    Journal of neurochemistry, 1975, Volume: 25, Issue:3

    Topics: Animals; Brain; Catalysis; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; gamma-Aminobutyric Acid; Keto Acids; Liver; Male; Methods; Phenylhydrazines; Rats; Transaminases; Tryptophan; Tyrosine

1975
Acute and chronic effects of 4-chloroamphetamine on monoamine metabolism in the rat brain.
    Psychopharmacologia, 1976, Volume: 46, Issue:1

    Topics: Amphetamines; Animals; Biogenic Amines; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Male; Norepinephrine; Normetanephrine; p-Chloroamphetamine; Rats; Serotonin; Time Factors; Tryptophan; Tyramine; Tyrosine

1976
Cholinergic and GABAergic mediations of the effects of apomorphine on serotonin neurons.
    Synapse (New York, N.Y.), 1992, Volume: 10, Issue:1

    Topics: Acetylcholine; Analysis of Variance; Animals; Apomorphine; Atropine; Bicuculline; Carbachol; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Male; Mecamylamine; Neurons; Pirenzepine; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1992
Thermogenic actions of tryptophan in the rat are mediated independently of 5-HT.
    Brain research, 1992, Apr-24, Volume: 578, Issue:1-2

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Body Temperature Regulation; Cerebral Ventricles; Corticotropin-Releasing Hormone; gamma-Aminobutyric Acid; Hypothalamus; Injections, Intraventricular; Male; Oxygen Consumption; Peptide Fragments; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Tryptophan

1992
The role of serotonin release and autoreceptors in the dorsalis raphe nucleus in the control of serotonin release in the cat caudate nucleus.
    Neuroscience, 1990, Volume: 39, Issue:3

    Topics: Animals; Cats; Caudate Nucleus; Female; gamma-Aminobutyric Acid; Kinetics; Male; Methiothepin; Phenethylamines; Picrotoxin; Raphe Nuclei; Serotonin; Tritium; Tryptophan

1990
Biochemistry and therapeutics of posthypoxic myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aspartic Acid; Benzodiazepines; Carbidopa; Electroencephalography; gamma-Aminobutyric Acid; Glycine; Humans; Hydroxyindoleacetic Acid; Hypoxia; Methysergide; Models, Biological; Myoclonus; Prednisone; Serotonin; Tryptophan; Valproic Acid

1986
Possible mechanisms of action of valproic acid in myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 4-Aminobutyrate Transaminase; 5-Hydroxytryptophan; Animals; Brain; gamma-Aminobutyric Acid; Glycine; Hydroxyindoleacetic Acid; Myoclonus; Pyridoxal Kinase; Rats; Serotonin; Tryptophan; Valproic Acid

1986
Lithium mechanisms in bipolar illness and altered intracellular calcium functions.
    Biological psychiatry, 1986, Volume: 21, Issue:5-6

    Topics: Adenylyl Cyclases; Bipolar Disorder; Calcium; Calcium-Transporting ATPases; Enzyme Activation; gamma-Aminobutyric Acid; Glycogen Synthase; Humans; Ion Channels; Lithium; Microtubules; Norepinephrine; Phosphoric Monoester Hydrolases; Synaptic Transmission; Tryptophan; Tyrosine 3-Monooxygenase

1986
Gabaergic interneurons in the dorsal raphe mediate the effects of apomorphine on serotonergic system.
    Brain research bulletin, 1987, Volume: 18, Issue:3

    Topics: Animals; Apomorphine; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Interneurons; Male; Picrotoxin; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Tryptophan

1987
An immunocytochemical study on the GABA-ergic and serotonin-ergic neurons in rat locus ceruleus with special reference to possible existence of the masked indoleamine cells.
    Acta histochemica, 1989, Volume: 87, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Cross Reactions; Female; Fenclonine; gamma-Aminobutyric Acid; Immune Sera; Immunoenzyme Techniques; Locus Coeruleus; Neurons; Pargyline; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Tryptophan

1989
Identification of putative neurotransmitters in the lizard parietal eye.
    Investigative ophthalmology & visual science, 1985, Volume: 26, Issue:5

    Topics: Acetylcholine; Animals; Eye; gamma-Aminobutyric Acid; Glutamates; Lizards; Neurotransmitter Agents; Serotonin; Tryptophan; Tyrosine

1985
Putative neurotransmitters in three experimental filariasis models.
    Life sciences, 1986, Oct-27, Volume: 39, Issue:17

    Topics: 5-Hydroxytryptophan; Animals; Dipetalonema; Dopamine; Epinephrine; Female; Filarioidea; gamma-Aminobutyric Acid; Male; Neurotransmitter Agents; Norepinephrine; Serotonin; Tryptophan

1986
Neurotransmitter amino acids in post-mortem brains of chronic schizophrenic patients.
    Psychiatry research, 1987, Volume: 22, Issue:4

    Topics: Adult; Aged; Amino Acids; Amygdala; Brain Chemistry; Chronic Disease; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurotransmitter Agents; Postmortem Changes; Schizophrenia; Tryptophan

1987
Amino acid analysis demonstrates that increased plasma free tryptophan causes the increase of brain tryptophan during exercise in the rat.
    Journal of neurochemistry, 1986, Volume: 46, Issue:5

    Topics: Alanine; Amino Acids; Animals; Brain; gamma-Aminobutyric Acid; Glycine; Lysine; Male; Physical Exertion; Rats; Rats, Inbred Strains; Stress, Physiological; Tryptophan

1986
Effect of tryptophan and GABA in oocyte growth of the Indian catfish Heteropneustes fossilis.
    Indian journal of experimental biology, 1987, Volume: 25, Issue:8

    Topics: Animals; Catfishes; Female; gamma-Aminobutyric Acid; Oocytes; Tryptophan

1987
Cerebrospinal fluid gamma-aminobutyric acid levels in dogs with chronic portosystemic encephalopathy.
    Clinical science (London, England : 1979), 1986, Volume: 71, Issue:6

    Topics: Ammonia; Animals; Dogs; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Tryptophan

1986
Could supplementary dietary tryptophan and taurine prevent epileptic seizures?
    Medical hypotheses, 1985, Volume: 18, Issue:4

    Topics: Diet; Epilepsy; gamma-Aminobutyric Acid; Humans; Melatonin; Monoamine Oxidase; Pineal Gland; Taurine; Tryptophan

1985
Influence of supidimide on brain neurotransmitter systems of rats and mice.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Aminobutyrate Transaminase; Adenylyl Cyclases; Animals; Binding, Competitive; Brain; Brain Chemistry; Catechol O-Methyltransferase; Dopamine; Electroshock; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Mice; Monoamine Oxidase; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, GABA-A; Serotonin; Species Specificity; Spiperone; Thalidomide; Tryptophan; Tyrosine 3-Monooxygenase

1984
Injectable and oral contraceptive steroids in relation to some neurotransmitters in the rat brain.
    Biochemical pharmacology, 1981, Jun-15, Volume: 30, Issue:12

    Topics: Acetylcholine; Animals; Brain; Contraceptives, Oral; Contraceptives, Oral, Synthetic; Depression; Female; gamma-Aminobutyric Acid; Glutamates; Humans; Neurotransmitter Agents; Rats; Serotonin; Tryptophan

1981
Noncatecholaminergic treatments of tardive dyskinesia.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Amantadine; Anti-Anxiety Agents; Benzodiazepines; Cyproheptadine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Double-Blind Method; Dyskinesia, Drug-Induced; Enkephalin, Methionine; gamma-Aminobutyric Acid; Humans; Lithium; Parasympathomimetics; Phenytoin; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Substance Withdrawal Syndrome; Tryptophan

1982
Similarity between the action of nicotinamide and diazepam on neurotransmitter metabolism in the rat [proceedings].
    Biochemical Society transactions, 1980, Volume: 8, Issue:1

    Topics: Alkynes; Aminocaproates; Amygdala; Animals; Brain; Diazepam; gamma-Aminobutyric Acid; Hippocampus; Hydroxyindoleacetic Acid; Male; Niacinamide; Organ Specificity; Rats; Serotonin; Tryptophan

1980
Changes in neurotransmitter metabolism following olfactory bulbectomy in the rat.
    Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Amygdala; Animals; Dopamine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hydroxyindoleacetic Acid; Male; Medial Forebrain Bundle; Mesencephalon; Neurotransmitter Agents; Norepinephrine; Olfactory Bulb; Olfactory Pathways; Rats; Rats, Inbred Strains; Serotonin; Tryptophan

1984
CSF neurochemistry of women with anorexia nervosa and normal women.
    The American journal of psychiatry, 1984, Volume: 141, Issue:11

    Topics: Adolescent; Adult; Anorexia Nervosa; Body Weight; Calcium; Choline; Depressive Disorder; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Phenylacetates; Tryptophan; Tyrosine

1984
CSF neurochemistry in depressed, manic, and schizophrenic patients compared with that of normal controls.
    The American journal of psychiatry, 1984, Volume: 141, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Calcium; Choline; Depressive Disorder; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Research Design; Schizophrenia; Tryptophan; Tyrosine

1984
Methylaplysinopsin and other marine natural products affecting neurotransmission.
    Federation proceedings, 1981, Volume: 40, Issue:1

    Topics: Animals; Brain; gamma-Aminobutyric Acid; Liver; Mice; Monoamine Oxidase Inhibitors; Porifera; Reflex; Serotonin; Spinal Cord; Synaptic Transmission; Terpenes; Tryptophan

1981
Purification of GABA on small columns of Dowex 50W; Combination with a method for separation of biogenic amines.
    Acta pharmacologica et toxicologica, 1980, Volume: 46, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; beta-Alanine; Biogenic Amines; Brain Chemistry; Chromatography, Ion Exchange; gamma-Aminobutyric Acid; Male; Norepinephrine; Rats; Tissue Extracts; Tryptophan

1980
Higher environmental temperature-induced increase in body temperature: involvement of serotonin in GABA mediated interaction of opioidergic system.
    Neurochemical research, 1993, Volume: 18, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Body Temperature; Endorphins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hot Temperature; Hydroxyindoleacetic Acid; Male; Methysergide; Morphine; Naloxone; Physostigmine; Rats; Serotonin; Tryptophan

1993
Glutamate, GABA, glycine and taurine modulate serotonin synthesis and release in rostral and caudal rhombencephalic raphe cells in primary cultures.
    Neurochemistry international, 1993, Volume: 23, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Kinetics; Neurons; Quinoxalines; Quisqualic Acid; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Taurine; Tryptophan

1993
Identification of tryptophan residues critical for the function and targeting of the gamma-aminobutyric acid transporter (subtype A).
    The Journal of biological chemistry, 1994, Jan-28, Volume: 269, Issue:4

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carrier Proteins; Cloning, Molecular; DNA Primers; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; HeLa Cells; Humans; Kinetics; Liposomes; Membrane Proteins; Membrane Transport Proteins; Methionine; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Organic Anion Transporters; Protein Structure, Secondary; Proteolipids; Recombinant Proteins; Tryptophan

1994
Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat.
    The Journal of clinical investigation, 1996, Jan-01, Volume: 97, Issue:1

    Topics: Acetylserotonin O-Methyltransferase; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminolevulinic Acid; Animals; Arylamine N-Acetyltransferase; Cells, Cultured; Enzyme Inhibitors; gamma-Aminobutyric Acid; Heme; Heptanoates; In Vitro Techniques; Isoproterenol; Male; Melatonin; Norepinephrine; Photoperiod; Pineal Gland; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Rats; Rats, Wistar; Tryptophan

1996
The neurochemical markers in cerebrospinal fluid to differentiate between aseptic and tuberculous meningitis.
    Neurochemistry international, 1998, Volume: 32, Issue:2

    Topics: Adult; Amino Acids; Aspartic Acid; Biomarkers; Diagnosis, Differential; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Homocysteine; Humans; Male; Meningitis, Aseptic; Middle Aged; Nitrites; Tryptophan; Tuberculosis, Meningeal; Vitamin B 12

1998
Changes in cerebrospinal fluid monoamine metabolites, tryptophan, and gamma-aminobutyric acid during the 1st year of life in normal infants. comparison with victims of sudden infant death syndrome.
    Biology of the neonate, 1999, Volume: 75, Issue:3

    Topics: Age Factors; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Infant, Premature; Methoxyhydroxyphenylglycol; Sudden Infant Death; Tryptophan

1999
A single hydrophobic residue confers barbiturate sensitivity to gamma-aminobutyric acid type C receptor.
    Molecular pharmacology, 1999, Volume: 55, Issue:3

    Topics: Amino Acid Sequence; Amino Acid Substitution; Chloride Channels; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Membrane Proteins; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Pentobarbital; Receptors, GABA; Recombinant Proteins; Sequence Homology, Amino Acid; Thiopental; Tryptophan

1999
Cerebral GABA release and GAD activity in protein- and tryptophan-restricted rats during development.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2002, Volume: 20, Issue:1

    Topics: Adaptation, Physiological; Animals; Animals, Newborn; Body Weight; Cerebral Cortex; Down-Regulation; Female; Food, Formulated; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Male; Neuronal Plasticity; Organ Size; Placental Insufficiency; Pregnancy; Presynaptic Terminals; Protein Deficiency; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Synaptic Transmission; Tryptophan; Up-Regulation

2002
Changes in plasma amino acids after electroconvulsive therapy of depressed patients.
    Psychiatry research, 2005, Dec-15, Volume: 137, Issue:3

    Topics: Adult; Aged; Aspartic Acid; Depressive Disorder, Major; Electroconvulsive Therapy; Electroencephalography; Electromyography; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Time Factors; Tryptophan

2005
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:11

    Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamic Acid; Glutarates; Glutaryl-CoA Dehydrogenase; Homoarginine; Humans; Lysine; Mice; Mice, Knockout; Mitochondria; Neurons; Nuclear Magnetic Resonance, Biomolecular; Tryptophan

2007
Mutations of the GABA-A receptor alpha1 subunit M1 domain reveal unexpected complexity for modulation by neuroactive steroids.
    Molecular pharmacology, 2008, Volume: 74, Issue:3

    Topics: Amino Acid Substitution; Animals; Cell Line; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Mutant Proteins; Mutation; Piperidines; Pregnanetriol; Pregnanolone; Pregnenolone; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Rats; Receptors, GABA-A; Serine; Steroids; Tryptophan

2008
Tryptophan mutations at azi-etomidate photo-incorporation sites on alpha1 or beta2 subunits enhance GABAA receptor gating and reduce etomidate modulation.
    Molecular pharmacology, 2008, Volume: 74, Issue:6

    Topics: Allosteric Regulation; Anesthetics, General; Animals; Binding Sites; Cell Line; Chloride Channels; Drug Synergism; Etomidate; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Ion Channel Gating; Mutation; Oocytes; Patch-Clamp Techniques; Photoaffinity Labels; Protein Structure, Tertiary; Protein Subunits; Receptors, GABA-A; Tryptophan; Xenopus laevis

2008
Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2).
    Biochimica et biophysica acta, 2011, Volume: 1808, Issue:1

    Topics: Amino Acid Transport Systems, Neutral; Amino Acids; Animals; Biological Transport; Dose-Response Relationship, Drug; Electrophysiology; gamma-Aminobutyric Acid; Inhibitory Concentration 50; Models, Chemical; Oocytes; Phenotype; Proline; Rats; Symporters; Tryptophan; Xenopus laevis

2011
The TM2 6' position of GABA(A) receptors mediates alcohol inhibition.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2

    Topics: Alcohols; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Cysteine; Cystine; DNA, Complementary; Drug Synergism; Electrophysiological Phenomena; Ethanol; Etomidate; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Methionine; Methyl Methanesulfonate; Molecular Dynamics Simulation; Oocytes; Patch-Clamp Techniques; Receptors, GABA-A; Tryptophan; Xenopus laevis

2012
Quorum sensing signaling molecules produced by reference and emerging soft-rot bacteria (Dickeya and Pectobacterium spp.).
    PloS one, 2012, Volume: 7, Issue:4

    Topics: 4-Butyrolactone; Acyl-Butyrolactones; Bacterial Proteins; Enterobacteriaceae; gamma-Aminobutyric Acid; Homoserine; Indoleacetic Acids; Kinetics; Lactones; Multienzyme Complexes; Pectobacterium; Quinolones; Quorum Sensing; RNA, Messenger; Signal Transduction; Solanum tuberosum; Tryptophan

2012
Tryptophan immunoadsorption for the treatment of autoimmune encephalitis.
    European journal of neurology, 2015, Volume: 22, Issue:1

    Topics: Adult; Aged; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Autoantibodies; Cytoskeletal Proteins; Encephalitis; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Immunosorbent Techniques; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Tryptophan; Young Adult

2015
Absence of aryl hydrocarbon receptors increases endogenous kynurenic acid levels and protects mouse brain against excitotoxic insult and oxidative stress.
    Journal of neuroscience research, 2015, Volume: 93, Issue:9

    Topics: Acetyltransferases; Animals; Basic Helix-Loop-Helix Transcription Factors; Brain; Disease Models, Animal; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Kynurenic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurotoxicity Syndromes; Oxidative Stress; Quinolinic Acid; Receptors, Aryl Hydrocarbon; Tryptophan

2015
Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification.
    Scientific reports, 2018, 05-01, Volume: 8, Issue:1

    Topics: Biomarkers; Cell Line; Chromatography, High Pressure Liquid; Endothelial Cells; Fatty Acids; gamma-Aminobutyric Acid; Glycocalyx; Human Umbilical Vein Endothelial Cells; Humans; Interferon-gamma; Kynurenine; Lipopolysaccharides; Lysophospholipids; Metabolome; Models, Biological; Nitric Oxide; Permeability; Polysaccharides; Prostaglandin D2; Sepsis; Sphingosine; Survival Analysis; Tryptophan

2018
Direct neurotransmitter activation of voltage-gated potassium channels.
    Nature communications, 2018, 05-10, Volume: 9, Issue:1

    Topics: Animals; Anticonvulsants; Binding Sites; CHO Cells; Cricetulus; gamma-Aminobutyric Acid; Ganglia, Spinal; KCNQ Potassium Channels; KCNQ3 Potassium Channel; Male; Mice; Molecular Docking Simulation; Neurons; Neurotransmitter Agents; Oocytes; Patch-Clamp Techniques; PC12 Cells; Phylogeny; Primary Cell Culture; Protein Binding; Rats; Sequence Alignment; Tryptophan; Xenopus laevis

2018
Exploratory metabolomics of nascent metabolic syndrome.
    Journal of diabetes and its complications, 2019, Volume: 33, Issue:3

    Topics: Adult; Aged; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Female; gamma-Aminobutyric Acid; Humans; Inflammation; Male; Metabolic Syndrome; Metabolomics; Middle Aged; Pyrrolidonecarboxylic Acid; Triglycerides; Tryptophan; Waist Circumference

2019
Neurotransmitter and tryptophan metabolite concentration changes in the complete Freund's adjuvant model of orofacial pain.
    The journal of headache and pain, 2020, Apr-21, Volume: 21, Issue:1

    Topics: Animals; Facial Pain; Freund's Adjuvant; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenic Acid; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Trigeminal Caudal Nucleus; Tryptophan; Vibrissae

2020
Plasma amino acids profile in first-episode psychosis, unaffected siblings and community-based controls.
    Scientific reports, 2020, 12-08, Volume: 10, Issue:1

    Topics: Adult; Amino Acids; Antipsychotic Agents; Body Mass Index; Case-Control Studies; Cross-Sectional Studies; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Glycine; Humans; Linear Models; Male; Proline; Psychotic Disorders; Siblings; Tryptophan; Young Adult

2020
Disturbance of neurotransmitter metabolism in drug-naïve, first-episode major depressive disorder: a comparative study on adult and adolescent cohorts.
    European archives of psychiatry and clinical neuroscience, 2022, Volume: 272, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Biomarkers; Depressive Disorder, Major; Dopamine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Methoxyhydroxyphenylglycol; Neurotransmitter Agents; Norepinephrine; Serotonin; Tryptophan; Vanilmandelic Acid

2022
Omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation.
    Journal of gastroenterology, 2022, Volume: 57, Issue:10

    Topics: Butyrates; Diarrhea; Fatty Acids, Volatile; Feces; gamma-Aminobutyric Acid; Glutamine; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Irritable Bowel Syndrome; Male; Melatonin; Microbiota; Pituitary-Adrenal System; RNA, Ribosomal, 16S; Serotonin; Symptom Flare Up; Tryptophan

2022
Rapid, sensitive analysis method for determining the nitrogen stable isotope ratio of total free amino acids in soil.
    Rapid communications in mass spectrometry : RCM, 2022, Nov-15, Volume: 36, Issue:21

    Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Histidine; Leucine; Lysine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Serine; Soil; Tryptophan

2022
Application and prospect of quasi-targeted metabolomics in age-related hearing loss.
    Hearing research, 2022, Volume: 424

    Topics: Acetylcholine; Amino Acids; Animals; Arginine; Chromatography, High Pressure Liquid; Coenzyme A; gamma-Aminobutyric Acid; Histamine; Methionine; Mice; Mice, Inbred C57BL; Piperidines; Presbycusis; Serotonin; Tandem Mass Spectrometry; Tryptophan

2022
Differential sensitivity of metabolic pathways in sugar beet roots to combined salt, heat, and light stress.
    Physiologia plantarum, 2022, Volume: 174, Issue:5

    Topics: Aspartic Acid; Beta vulgaris; Chlorides; Citric Acid; Cysteine; gamma-Aminobutyric Acid; Gene Expression Regulation, Plant; Glucose; Hot Temperature; Mannitol; Metabolic Networks and Pathways; Plant Roots; Proline; Salinity; Salts; Sodium Chloride; Stress, Physiological; Sugars; Tryptophan; Tyrosine

2022
Metabolites for monitoring symptoms and predicting remission in patients with depression who received electroconvulsive therapy: a pilot study.
    Scientific reports, 2023, 08-14, Volume: 13, Issue:1

    Topics: Biomarkers; Depression; Depressive Disorder, Major; Electroconvulsive Therapy; gamma-Aminobutyric Acid; Humans; Pilot Projects; Treatment Outcome; Tryptophan

2023
Metagenomics-based inference of microbial metabolism towards neuroactive amino acids and the response to antibiotics in piglet colon.
    Amino acids, 2023, Volume: 55, Issue:10

    Topics: Amino Acids; Animals; Anti-Bacterial Agents; Colon; gamma-Aminobutyric Acid; Glutamic Acid; Kynurenine; Putrescine; Swine; Transaminases; Tryptophan

2023