tryptophan and fluorine

tryptophan has been researched along with fluorine in 111 studies

Research

Studies (111)

TimeframeStudies, this research(%)All Research%
pre-199056 (50.45)18.7374
1990's16 (14.41)18.2507
2000's25 (22.52)29.6817
2010's9 (8.11)24.3611
2020's5 (4.50)2.80

Authors

AuthorsStudies
Birdsall, B; Burgen, AS; Feeney, J; Griffiths, DV; Kimber, BJ; Roberts, GC; Sykes, BD1
Harada, M; Kido, R; Koga, K; Miura, I; Nishitani, H1
Falke, JJ; Luck, LA1
d'Avignon, A; Gordon, JI; Li, E; Qian, SJ; Yang, NC1
Everett, MM1
Sahm, U1
Johnson, RW; Kenney, FT1
Favorova, OO; Kochkina, LL; Lavrik, OI; Nevinsky, GA; Petrova, TD; Savchenko, TI1
Godfrey, OW1
Udenfriend, S1
Hrdina, PD; Ling, GM; Peters, DA; Singhal, RL1
Peters, DA2
Crewther, P; Davidson, BE; Dopheide, TA1
Eubanks, EE; Jacobs, BL; Wise, WD1
Oswald, I1
Feigelson, P; Koike, K2
Beck, CF; Ingraham, JL; Kleker, E; Neuhard, J; Thomassen, E1
Cihak, A; Pitot, HC; Wilkinson, D1
Kuhn, JC; Pabst, MJ; Somerville, RL1
Peralta, EG; Segura, J1
Widholm, JM2
Kumbar, M; Sankar, DV1
Goldberg, AL; Prouty, WF2
Collins, JS; Packter, NM1
Wilcox, M1
Coy, DH; Coy, EJ; Hirotsu, Y; Schally, AV; Tesser, GI; van Nispen, JW; Vilchez-Martinez, JA1
Bosin, TR; Hall, LE; Hegeman, GD1
Calhoun, DH; Jensen, RA1
Hartley, R; Smith, JA1
Costa, E; Löfstrandh, S; Morgan, D1
Cottrall, MF; Taylor, DM1
Brady, FO; Feigelson, P1
Dorrington, KJ; Hofmann, T1
Wells, MA1
Herskovits, TT; Solli, NJ1
Hrdina, PD; Peters, DA; Singhal, RL1
Browne, DR; Hegeman, GD; Kenyon, GL1
Feigelson, P; Forman, HJ1
Ericsson, LH; Hermodson, MA; Neurath, H; Titani, K; Walsh, KA1
Billups, C; Kay, E; Strickland, EH1
Costa, E; Groppetti, A; Misher, A; Naimzada, M; Revuelta, A1
Atkins, HL; Christman, DR; Fowler, JS; Hauser, W; Hoyte, RM; Klopper, JF; Lin, SS; Wolf, AP1
Gerig, JT; Rimerman, RA1
Horton, HR; Naik, VR1
Coulson, WF; Hughes, CM1
Bailey, CJ; Boulter, D1
Fonss-Bech, P; Schmidt, KD1
Billups, C; Horwitz, J; Strickland, EH1
Elander, RP; Gorman, M; Hamill, RL; Mabe, JA1
Elander, RP; Gorman, M; Hamill, RL; Mabe, J1
Brown, JH; Mackey, HK1
Coulson, WF; Jepson, JB; Wardle, E1
Bidlingmaier, F; Schneider, F1
Cottam, PF; Ho, C; Post, JF; Simplaceanu, V1
Frieden, C; Hoeltzli, SD3
Harrell, S; Laws, D; Le, H; Lian, C; Matsumura, I; Montez, B; Oldfield, E; Patterson, J; Pearson, J1
Groetsch, SM; Ho, C; Homer, RJ; Hsue, PY; Kulig, CE; Pratt, EA; Sun, ZY; Sutherland, DC; Truong, HT1
London, RE; Luck, LA; O'Connell, TM; Vance, JE1
Ho, C; Pratt, EA; Simplaceanu, V; Sun, ZY1
Gerig, JT; Lau, EY1
Eftink, MR; Wong, CY1
Baird, LC; Bingham, NC; Busath, DD; Cole, CD; Cotten, M; Cross, TA; Hendershot, RJ; Hendershot, RW; Maughan, P; Morrison, S; Phillips, LR; Thulin, CD1
Nadanaciva, S; Senior, AE; Weber, J1
Nadanaciva, S; Senior, AE; Weber, J; Wilke-Mounts, S1
Luck, LA; Nemerson, Y; Ross, JB; Rusinova, E; Zemsky, J1
Barse, JL; Luck, AM; Luck, LA; Peck, CH1
Choi, JW; Jung, S; Kim, HW; Lee, HW; Sohn, JH; Yeh, BI1
Anderson, DG; Busath, DD; Cross, TA; Shirts, RB1
Bann, JG; Frieden, C; Hultgren, SJ; Pinkner, J1
Aziz, R; Campos-Olivas, R; Evans, JN; Gronenborn, AM; Helms, GL1
Jaenicke, R; Kalbitzer, HR; Kremer, W; Schuler, B1
Busath, DD; Cole, CD; Cotten, M; Cross, TA; Frost, AS; Thompson, N1
Pellecchia, M; Rodriguez-Mias, RA1
Leone, M; Pellecchia, M; Rodriguez-Mias, RA1
Honek, JF; Luck, LA; Salopek-Sondi, B; Skeels, MC; Vaughan, MD1
EZEKIEL, DH1
Frieden, C; Shu, Q1
Abbott, GL; Blouse, GE; Luck, LA; Perron, MJ; Shore, JD; Szabo, AG1
Campbell, ID; Colebrooke, SA; Greene, LH; Neerathilingam, M; Staunton, D1
Anderluh, G; Macek, P; Norton, RS; Podlesek, Z; Razpotnik, A; Separovic, F1
Letourneau, PJ; Mercier, P; Sykes, BD; Wang, X1
Boyer, JA; Dalessio, PM; Ropson, IJ1
Gray, HB; Harkins, SB; Lee, JC; Winkler, GR1
Bezsonova, I; Evanics, F; Forman-Kay, JD; Kitevski, JL; Marsh, J; Prosser, RS1
Frieden, C; Li, H1
Hong, M; Luo, W; Mani, R1
Franks, WT; Graesser, DT; Nieuwkoop, AJ; Rienstra, CM; Wylie, BJ1
Cross, TA; Fu, R; Nozirov, F; Sternberg, U; Ulrich, AS; Witter, R1
Broos, J; Nabuurs, SM; van Amerongen, H; van Hoek, A; van Mierlo, CP; Visser, AJ; Visser, NV; Westphal, AH1
Grage, SL; Klipfel, M; Sternberg, U; Ulrich, AS; Witter, R1
Han, X; Huang, KW; Kwiatkowski, J; Lu, Y; Xue, F1
Coutant, J; Dalvit, C; Gossert, AD; Piotto, M1
Crowley, PB; Kyne, C; Monteith, WB1
Baell, JB; Harjani, JR; Leung, EW; Mulcair, MD; Norton, RS; Scanlon, MJ; Yagi, H1
Ahern, CA; Galpin, JD; Kim, RY; Kurata, HT; Pless, SA; Seebohm, G; Yau, MC1
Bruner, SD; Dedic, E; Ding, Y; Huguet-Tapia, JC; Loria, R; Mehta, M; Zhang, Y; Zuo, R1
Bai, S; Dybowski, C; Fritz, M; Gronenborn, AM; Holmes, ST; Kraus, J; Lu, M; Maas, W; Polenova, T; Quinn, CM; Sarkar, S; Sergeyev, IV; Struppe, J; Wang, M; Yap, GPA1
Arai, M; Ikeda, H; Ikejiri, Y; Kitani, S; Namba, T; Nihira, T; Nishimoto, Y; Ueda, S1
Gronenborn, AM; Ishima, R; Lu, M; Polenova, T1
Dunlap, LE; Olson, DE; Saunders, CM; Tantillo, DJ; Tombari, RJ; Wu, CY1
Kovermann, M; Mayans, O; Mihajlenko, X; Welte, H; Zhou, T1
Avagliano, C; Cervenka, S; Erhardt, S; Häggkvist, J; Johnström, P; Kondrashov, M; Krasikova, R; Petukhov, M; Revunov, E; Schou, M; Tari, L; Tóth, M; Vazquez-Romero, A1
Aihara, H; Banerjee, R; Jones, JC; Lipscomb, JD; Pomerantz, WCK; Semonis, MM; Shi, K1
Abdelkader, EH; Herath, ID; Huber, T; Otting, G; Qianzhu, H1
Krempl, C; Sprangers, R1

Reviews

2 review(s) available for tryptophan and fluorine

ArticleYear
Arene oxide intermediates in enzymatic hydroxylation and their significance with respect to drug toxicity.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Acetanilides; Amphetamine; Bromine; Chemical Phenomena; Chemistry; Chlorine; Deuterium; Ethers, Cyclic; Fenclonine; Fluorine; Glutathione; Mixed Function Oxygenases; Naphthalenes; Phenols; Phenylalanine; Phenylpyruvic Acids; Tritium; Tryptophan

1971
The effect of pyrimidine analogues and tryptophan on enzyme synthesis and degradation in rat liver.
    Advances in enzyme regulation, 1970, Volume: 9

    Topics: Adrenalectomy; Animals; Carbon Isotopes; Caseins; Centrifugation, Density Gradient; Cortisone; Cytidine; Dactinomycin; Enzyme Induction; Fluorine; L-Serine Dehydratase; Leucine; Liver; Lyases; Male; Nucleoproteins; Nucleosides; Ornithine; Orotic Acid; Phenylpyruvic Acids; Protein Hydrolysates; Pyrimidines; Rats; Ribosomes; RNA; Time Factors; Transaminases; Triazines; Tritium; Tryptophan; Tryptophan Oxygenase; Tyrosine Transaminase

1970

Other Studies

109 other study(ies) available for tryptophan and fluorine

ArticleYear
Proximity of two tryptophan residues in dihydrofolate reductase determined by 19f NMR.
    Nature, 1978, Jan-12, Volume: 271, Issue:5641

    Topics: Fluorine; Magnetic Resonance Spectroscopy; Protein Conformation; Tetrahydrofolate Dehydrogenase; Tryptophan

1978
In vivo 19F MR spectroscopic study of metabolism of 5-fluorotryptophan in rat liver.
    Acta radiologica (Stockholm, Sweden : 1987), 1992, Volume: 33, Issue:3

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Fluorine; Liver; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Tryptophan

1992
Open conformation of a substrate-binding cleft: 19F NMR studies of cleft angle in the D-galactose chemosensory receptor.
    Biochemistry, 1991, Jul-02, Volume: 30, Issue:26

    Topics: Amino Acid Sequence; Binding Sites; Computer Graphics; Edetic Acid; Escherichia coli; Fluorine; Gadolinium; Galactose; Glucose; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Organometallic Compounds; Protein Conformation; Receptors, Cell Surface; Tryptophan

1991
19F nuclear magnetic resonance studies of 6-fluorotryptophan-substituted rat cellular retinol binding protein II produced in Escherichia coli. An analysis of four tryptophan substitution mutants and their interactions with all-trans-retinol.
    The Journal of biological chemistry, 1990, Jul-15, Volume: 265, Issue:20

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Escherichia coli; Fluorine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Protein Binding; Rats; Recombinant Proteins; Retinol-Binding Proteins; Retinol-Binding Proteins, Cellular; Tryptophan; Vitamin A

1990
Deamination by the diazotization-deazotization method.
    The Histochemical journal, 1973, Volume: 5, Issue:1

    Topics: Benzene Derivatives; Chemical Phenomena; Chemistry; Connective Tissue; Deamination; Diazonium Compounds; Epithelium; Evaluation Studies as Topic; Fluorine; Gingiva; Histocytochemistry; Humans; Keratins; Lysine; Nitro Compounds; Proteins; Staining and Labeling; Tryptophan; Tyrosine

1973
[The effect of L-2,5-dihydrophenylalanine].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1972, Volume: 220, Issue:1

    Topics: Aldehyde-Lyases; Anti-Bacterial Agents; Bacterial Proteins; Binding, Competitive; Cyclohexanecarboxylic Acids; Escherichia coli; Feedback; Fluorine; Heptoses; Isoenzymes; Microbial Sensitivity Tests; Oxidoreductases; Phenylalanine; Phosphoenolpyruvate; Protein Biosynthesis; Pyruvates; Tetroses; Tryptophan; Tyrosine

1972
Regulation of tyrosine aminotransferase in rat liver. XI. Studies on the relationship of enzyme stability to enzyme turnover in cultured hepatoma cells.
    The Journal of biological chemistry, 1973, Jul-10, Volume: 248, Issue:13

    Topics: Amino Acids; Animals; Antigen-Antibody Reactions; Carbon Isotopes; Carcinoma, Hepatocellular; Catalysis; Cells, Cultured; Culture Media; Drug Stability; Enzyme Induction; Fluorine; Hot Temperature; Hydrocortisone; Liver; Liver Neoplasms; Protein Denaturation; Rabbits; Rats; Structure-Activity Relationship; Tritium; Tryptophan; Tyrosine Transaminase

1973
Fluorinated tryptophans as substrates and inhibitors of the ATP--(32P)PPi exchange reaction catalysed by tryptophanyl tRNA synthetase.
    FEBS letters, 1974, Jul-15, Volume: 43, Issue:2

    Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Binding, Competitive; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; D-Amino-Acid Oxidase; Diphosphates; Electrophoresis, Polyacrylamide Gel; Fluorine; Kidney; Kinetics; Molecular Weight; Pancreas; Phosphorus Radioisotopes; Protein Binding; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine; Tryptophan; Ultrafiltration

1974
Directed mutation in Streptomyces lipmanii.
    Canadian journal of microbiology, 1974, Volume: 20, Issue:11

    Topics: Bacillus subtilis; Biological Assay; Carbon Radioisotopes; Cephalosporins; Cycloserine; DNA Replication; DNA, Bacterial; Fluorine; Genes; Hydrogen-Ion Concentration; Leucine; Mutagens; Mutation; Nitrosoguanidines; Penicillin Resistance; Penicillins; Pseudomonas; Salmonella; Streptomyces; Thymidine; Tritium; Tryptophan

1974
The role of brain serotonin in DDT-induced hyperpyrexia.
    Journal of neurochemistry, 1972, Volume: 19, Issue:4

    Topics: Animals; Brain; Brain Stem; DDT; Fenclonine; Fever; Fluorine; Hydroxyindoleacetic Acid; Male; Pargyline; Rats; Seizures; Serotonin; Tremor; Tryptophan

1972
Inhibition of brain tryptophan-5-hydroxylase by amino acids--the role of L-tryptophan uptake inhibition.
    Biochemical pharmacology, 1972, Apr-01, Volume: 21, Issue:7

    Topics: Animals; Brain; Bromine; Carbon Isotopes; Chlorine; Fenclonine; Fluorine; In Vitro Techniques; Kinetics; Male; Methylation; Mixed Function Oxygenases; Nitro Compounds; Phenylalanine; Rats; Stereoisomerism; Subcellular Fractions; Synaptosomes; Tryptophan

1972
Chorismate mutase-prephenate dehydratase from Escherichia coli K-12. II. Kinetic properties.
    The Journal of biological chemistry, 1972, Jul-25, Volume: 247, Issue:14

    Topics: Animals; Benzyl Compounds; Cattle; Chlorine; Cyclohexanecarboxylic Acids; Cyclohexanes; Dithiothreitol; Enzyme Activation; Escherichia coli; Fenclonine; Fluorine; Formates; Hydro-Lyases; Hydrogen-Ion Concentration; Isomerases; Kinetics; Mercaptoethanol; Phenols; Phenylalanine; Propionates; Pyruvates; Serum Albumin, Bovine; Stereoisomerism; Tryptophan

1972
Effect of indolealkylamine manipulations on locomotor activity in rats.
    Neuropharmacology, 1974, Volume: 13, Issue:7

    Topics: Amines; Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Diet; Fenclonine; Fluorine; Food Deprivation; Humans; Indoles; Male; Monoamine Oxidase Inhibitors; Motor Activity; Pargyline; Phenoxybenzamine; Propranolol; Rats; Serotonin; Spiro Compounds; Stereotyped Behavior; Stimulation, Chemical; Time Factors; Tryptophan; Tryptophan Hydroxylase

1974
Sleep.
    Experimental medicine and surgery, 1969, Volume: 27, Issue:1-2

    Topics: Amobarbital; Appetite Depressants; Barbiturates; Dreams; Electroencephalography; Fenfluramine; Fluorine; Humans; Methysergide; Narcolepsy; Phenethylamines; Sleep; Sleep Stages; Sleep, REM; Substance-Related Disorders; Time Factors; Tranylcypromine; Tryptophan

1969
Studies on the roles of the catalytic and allosteric sites in modulating the reactivity of tryptophan oxygenase with heme ligands. I. Cyanide derivatives.
    Biochemistry, 1971, Aug-31, Volume: 10, Issue:18

    Topics: Allosteric Regulation; Binding Sites; Catalysis; Chemical Phenomena; Chemistry, Physical; Cyanides; Electron Spin Resonance Spectroscopy; Fluorine; Guanidines; Heme; Hydrochloric Acid; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Nitriles; Oxidation-Reduction; Peroxidases; Plants; Potassium; Protein Binding; Protein Conformation; Protein Denaturation; Pseudomonas; Spectrophotometry; Sulfites; Tryptophan; Tryptophan Oxygenase

1971
Salmonella typhimurium mutants defective in cytidine monophosphate kinase (cmk).
    Journal of bacteriology, 1974, Volume: 120, Issue:3

    Topics: Autoradiography; Carbon Radioisotopes; Chromosome Mapping; Cytidine; Cytosine Nucleotides; Deoxycytidine Monophosphate; Fluorine; Genes; Mutagens; Mutation; Nitrosoguanidines; Oxidative Phosphorylation; Phosphorus Radioisotopes; Phosphotransferases; Salmonella typhimurium; Transduction, Genetic; Tryptophan; Ultraviolet Rays; Uridine

1974
Mutant strains of Escherichia coli K-12 exhibiting enhanced sensitivity to 5-methyltryptophan.
    Journal of bacteriology, 1972, Volume: 112, Issue:1

    Topics: Aspartate-Semialdehyde Dehydrogenase; Aza Compounds; Cell-Free System; Chromosome Mapping; Chromosomes, Bacterial; Drug Resistance, Microbial; Escherichia coli; Feedback; Fluorine; Fluorometry; Glutamine; Methylation; Microbial Sensitivity Tests; Mutation; Operon; ortho-Aminobenzoates; Phosphotransferases; Protein Biosynthesis; Stereoisomerism; Transaminases; Transduction, Genetic; Tryptophan; Tryptophan Synthase

1972
Gas chromatography-mass spectrometry of catecholamines and tryptamines: determination of gas chromatographic profiles of the amines, their precursors and their metabolites.
    Journal of chromatographic science, 1974, Volume: 12, Issue:11

    Topics: Catecholamines; Chromatography, Gas; Fluorine; Indoles; Kinetics; Mass Spectrometry; Methods; Microchemistry; Phenylalanine; Propionates; Tryptamines; Tryptophan

1974
Tryptophan biosynthesis in Nicotiana tabacum and Daucus carota cell cultures: site of action of inhibitory tryptophan analogs.
    Biochimica et biophysica acta, 1972, Jan-28, Volume: 261, Issue:1

    Topics: 5-Hydroxytryptophan; Acrylates; Cells, Cultured; Cyclohexanecarboxylic Acids; Fluorine; Glycerophosphates; Hydro-Lyases; Indoles; Methylation; Nicotiana; ortho-Aminobenzoates; Plant Development; Plants; Plants, Toxic; Serine; Transaminases; Tryptophan

1972
Cultured Nicotiana tabacum cells with an altered anthranilate synthetase which is less sensitive to feedback inhibition.
    Biochimica et biophysica acta, 1972, Jan-28, Volume: 261, Issue:1

    Topics: 5-Hydroxytryptophan; Acrylates; Cells, Cultured; Feedback; Fluorine; Indoles; Methylation; Nicotiana; ortho-Aminobenzoates; Plants; Plants, Toxic; Transaminases; Tryptophan

1972
Quantum chemical studies on drug actions. II. Quantum chemical data on derivatives of catechol, indole, imidazole amines and of spermine and spermidine.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 5, Issue:1

    Topics: 5-Hydroxytryptophan; Amines; Catecholamines; Catechols; Chemical Phenomena; Chemistry; Dopamine; Epinephrine; Fluorine; Hallucinogens; Histamine; Hydroxyindoleacetic Acid; Hydroxylation; Imidazoles; Indoles; Mandelic Acids; Norepinephrine; Normetanephrine; Phenethylamines; Quantum Theory; Serotonin; Spermidine; Spermine; Sulfhydryl Compounds; Tryptamines; Tryptophan; Tyramine

1973
Effects of protease inhibitors on protein breakdown in Escherichia coli.
    The Journal of biological chemistry, 1972, May-25, Volume: 247, Issue:10

    Topics: Amidines; Aminobutyrates; Bacterial Proteins; Benzyl Compounds; Canavanine; Chlorine; Culture Media; Enzyme Induction; Escherichia coli; Fluorine; Galactosidases; Hydro-Lyases; Isoflurophate; Leucine; Protease Inhibitors; Serine; Sulfonic Acids; Toluene; Tosyl Compounds; Tritium; Trypsin Inhibitors; Tryptophan

1972
Fate of abnormal proteins in E. coli accumulation in intracellular granules before catabolism.
    Nature: New biology, 1972, Nov-29, Volume: 240, Issue:100

    Topics: Arginine; Aza Compounds; Bacterial Proteins; Canavanine; Carbon Isotopes; Cell Fractionation; Centrifugation, Density Gradient; Escherichia coli; Fluorine; Hydrazones; Leucine; Nitriles; Oxidative Phosphorylation; Phenylhydrazines; Tritium; Tryptophan

1972
Effect of inhibitors of protein synthesis on the formation of phenols derived from acetate and shikimic acid in Aspergillus fumigatus.
    European journal of biochemistry, 1974, Feb-15, Volume: 42, Issue:1

    Topics: Acetates; Aspergillus fumigatus; Azaguanine; Benzoates; Benzyl Compounds; Culture Media; Cycloheximide; Fluorine; Fungal Proteins; Nitriles; Phenols; Phenylalanine; Phenylpyruvic Acids; Shikimic Acid; Toluene; Tryptophan; Tyrosine

1974
The enzymatic synthesis of L-tryptophan analogues.
    Analytical biochemistry, 1974, Volume: 59, Issue:2

    Topics: Alcohols; Aza Compounds; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Escherichia coli; Fluorine; Indoles; Isotope Labeling; Methyl Ethers; Phosphatidylcholines; Pyrimidines; Serine; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Tryptophan Synthase

1974
Investigation of the role of tryptophan in the luteinizing hormone-releasing hormone.
    Biochemistry, 1974, Aug-13, Volume: 13, Issue:17

    Topics: Amino Acids; Amino Acids, Diamino; Animals; Biological Assay; Castration; Dose-Response Relationship, Drug; Electron Transport; Female; Fluorine; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Histidine; Luteinizing Hormone; Male; Nitro Compounds; Phenylalanine; Rats; Sex Factors; Structure-Activity Relationship; Tryptophan

1974
Incorporation of tryptophan and its benzo(b)thiophene, 1-methylindole, and indene analogs into protein of Escherichia coli.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 9, Issue:1

    Topics: Bacterial Proteins; Carbon Radioisotopes; Escherichia coli; Fluorine; Galactosidases; Glycerol; Indenes; Indoles; Leucine; Thiophenes; Time Factors; Tritium; Tryptophan

1974
Significance of altered carbon flow in aromatic amino acid synthesis: an approach to the isolation of regulatory mutants in Pseudomonas aeruginosa.
    Journal of bacteriology, 1972, Volume: 109, Issue:1

    Topics: Alanine; Amino Acids; Biological Assay; Carbon; Cell-Free System; Culture Media; Cyclohexanecarboxylic Acids; Drug Resistance, Microbial; Fluorine; Fluorometry; Fructose; Genetics, Microbial; Hydro-Lyases; Leuconostoc; Methods; Mutation; ortho-Aminobenzoates; Pentosyltransferases; Phenylalanine; Pseudomonas aeruginosa; Transaminases; Tryptophan; Tyrosine

1972
Inhibition of catecholamine oxidation by indoles.
    Biochemical pharmacology, 1972, Aug-01, Volume: 21, Issue:15

    Topics: 5-Hydroxytryptophan; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Dopamine Antagonists; Fluorine; Fungi; Indoles; Kinetics; Melatonin; Monophenol Monooxygenase; Oxidation-Reduction; Serotonin; Spectrophotometry; Tryptamines; Tryptophan

1972
Amphetamine analogues and brain amines.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Jan-15, Volume: 11, Issue:2

    Topics: Amphetamine; Animals; Biogenic Amines; Brain Chemistry; Brain Stem; Carbon Isotopes; Chlorphentermine; Fluorine; Hydrocarbons, Halogenated; Hypothalamus; Male; Mephentermine; Methamphetamine; Monoamine Oxidase Inhibitors; Norepinephrine; Phenethylamines; Propylamines; Rats; Serotonin; Structure-Activity Relationship; Telencephalon; Tritium; Tryptophan; Tryptophan Hydroxylase; Tyramine

1972
18 F labelled amino acids for pancreas scanning.
    The British journal of radiology, 1973, Volume: 46, Issue:542

    Topics: Amino Acids; Animals; Fluorine; Humans; Pancreas; Phenylalanine; Radioisotopes; Radionuclide Imaging; Rats; Tryptophan

1973
Photoactivation of pseudomonad L-tryptophan oxygenase by electron ejection from its substrate, L-tryptophan.
    Archives of biochemistry and biophysics, 1973, Volume: 156, Issue:2

    Topics: Allosteric Regulation; Binding Sites; Catalase; Copper; Enzyme Activation; Fluorine; Formates; Kinetics; Methylation; Oxidation-Reduction; Protein Binding; Pseudomonas; Radiation Effects; Spectrophotometry; Superoxide Dismutase; Tryptophan; Tryptophan Oxygenase; Ultraviolet Rays

1973
Effects of ionic strength on the circular dichroism spectrum of chymotrypsin.
    Canadian journal of biochemistry, 1973, Volume: 51, Issue:7

    Topics: Acetates; Chemical Phenomena; Chemistry; Chlorides; Chymotrypsin; Chymotrypsinogen; Circular Dichroism; Fluorine; Isoleucine; Kinetics; Lithium; Macromolecular Substances; Nitric Oxide; Organophosphonates; Osmolar Concentration; Phosphoric Acids; Sodium; Sodium Chloride; Tryptophan; Ultracentrifugation; Ultraviolet Rays

1973
Effects of chemical modification on the activity of Crotalus adamanteus Phospholipase A 2 . Evidence for an essential amino group.
    Biochemistry, 1973, Mar-13, Volume: 12, Issue:6

    Topics: Acylation; Amino Acids; Anhydrides; Animals; Binding Sites; Chromatography, Gel; Ethyl Ethers; Fluorine; Formates; Iodine; Iodoacetates; Lysine; Macromolecular Substances; Nitrobenzenes; Oxidation-Reduction; Phospholipases; Protein Conformation; Snakes; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Succinimides; Tryptophan; Urea

1973
Solvent perturbation studies and analysis of protein and model compound data in denaturing organic solvents.
    Analytical biochemistry, 1973, Volume: 54, Issue:2

    Topics: 1-Propanol; Acetates; Alcohols; Animals; Apoproteins; Cattle; Cetacea; Chlorine; Dimethyl Sulfoxide; Ethanol; Fluorine; Mathematics; Methanol; Methods; Myoglobin; Ovalbumin; Protein Denaturation; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine

1973
Role of noradrenaline, 5-hydroxytryptamine and acetylcholine in the hypothermic and convulsive effects of alpha-chlordane in rats.
    European journal of pharmacology, 1974, Volume: 26, Issue:2

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Body Temperature; Brain; Brain Chemistry; Brain Stem; Cerebral Cortex; Chlordan; Corpus Striatum; Dose-Response Relationship, Drug; Fluorine; Hindlimb; Hydroxyindoleacetic Acid; Male; Methyltyrosines; Norepinephrine; Paralysis; Rats; Seizures; Serotonin; Time Factors; Tryptophan

1974
Incorporation of monoflurotryptophans into protein during the growth of Escherichia coli.
    Biochemical and biophysical research communications, 1970, Apr-08, Volume: 39, Issue:1

    Topics: Bacterial Proteins; Carbon Isotopes; Depression, Chemical; Escherichia coli; Fluorine; Galactosidases; Glycine; Hydrolases; Microscopy, Phase-Contrast; Mixed Function Oxygenases; Mutation; Tryptophan

1970
The effects of allosteric interaction on the kinetics, spectra, and tertiary structure of pseudomonad tryptophan oxygenase.
    The Journal of biological chemistry, 1972, Jan-10, Volume: 247, Issue:1

    Topics: Allosteric Regulation; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Detergents; Drug Stability; Fluorine; Heme; Iron; Kinetics; Oxygen; Protein Binding; Protein Conformation; Pseudomonas; Spectrophotometry; Sulfuric Acids; Tryptophan; Tryptophan Oxygenase; Ultraviolet Rays

1972
Amino acid sequence of thermolysin. Isolation and characterization of the fragments obtained by cleavage with cyanogen bromide.
    Biochemistry, 1972, Jun-20, Volume: 11, Issue:13

    Topics: Amino Acid Sequence; Amino Acids; Carbohydrates; Carboxypeptidases; Chromatography, Gel; Chromatography, Paper; Cyanates; Cyanogen Bromide; Electrophoresis; Endopeptidases; Fluorine; Guanidines; Isoleucine; Lysine; Molecular Weight; Nitrobenzenes; Sodium Dodecyl Sulfate; Spectrophotometry; Thermolysin; Tryptophan; Tyrosine; Ultraviolet Rays

1972
Effects of hydrogen bonding and solvents upon the tryptophanyl 1 L a absorption band. Studies using 2,3-dimethylindole.
    Biochemistry, 1972, Sep-12, Volume: 11, Issue:19

    Topics: Acetamides; Acetates; Amides; Butanols; Carboxylic Acids; Chemical Phenomena; Chemistry; Cold Temperature; Cyclohexanes; Fluorine; Histidine; Hydrocarbons, Halogenated; Hydrogen; Imidazoles; Indoles; Methane; Peptides; Proteins; Spectrophotometry; Tryptophan; Ultraviolet Rays

1972
Evidence that in rats 1-benzyl- -methoxy-3-trifluoromethylphenethylamine (SK& F 1-39728) dissociates anorexia from central stimulation and actions on brain monoamine stores.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 182, Issue:3

    Topics: Animals; Appetite; Appetite Depressants; Benzyl Compounds; Biogenic Amines; Body Temperature; Brain; Brain Chemistry; Central Nervous System; Dextroamphetamine; Dopamine; Fenfluramine; Fluorine; Kinetics; Male; Motor Activity; Norepinephrine; Phenethylamines; Rats; Rats, Inbred Strains; Serotonin; Stimulation, Chemical; Tritium; Tryptophan; Tyrosine

1972
Organic radiopharmaceuticals labeled with isotopes of short half-life. V. 18 F-labeled 5- and 6-fluorotryptophan.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1972, Volume: 13, Issue:10

    Topics: Animals; Chemical Phenomena; Chemistry; Dogs; Fluorine; Half-Life; Injections, Intravenous; Isotope Labeling; Liver; Methionine; Methods; Mice; Pancreas; Radioisotopes; Radionuclide Imaging; Rats; Selenium; Tryptophan

1972
Nuclear magnetic resonance studies of the interaction of N-trifluoroacetyltryptophanate with -chymotrypsin.
    Journal of the American Chemical Society, 1972, Oct-18, Volume: 94, Issue:21

    Topics: Acetates; Chemical Phenomena; Chemistry; Chymotrypsin; Fluorine; Kinetics; Magnetic Resonance Spectroscopy; Tryptophan

1972
Reaction of 2-hydroxy-5-nitrobenzylated carboxypeptidase A with 14 C-1-fluoro-2,4-dinitrobenzene.
    Biochemical and biophysical research communications, 1971, Jul-02, Volume: 44, Issue:1

    Topics: Alanine; Alkylation; Amino Acids; Aspartic Acid; Benzyl Compounds; Carbon Isotopes; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dinitrophenols; Fluorine; Fluorometry; Guanidines; Hydrolysis; Nitrobenzenes; Nitrophenols; Protein Denaturation; Serine; Spectrophotometry; Tryptophan; Ultraviolet Rays

1971
Studies on the catalytic and allosteric sites in modulating the reactivity of tryptophan oxygenase with heme ligands. II. Carbon monoxide derivatives.
    Biochemistry, 1971, Aug-31, Volume: 10, Issue:18

    Topics: Allosteric Regulation; Binding Sites; Carbon Monoxide; Catalysis; Chemical Phenomena; Chemistry; Fluorine; Heme; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Oxidation-Reduction; Protein Binding; Protein Conformation; Pseudomonas; Spectrophotometry; Sulfites; Tryptophan; Tryptophan Oxygenase

1971
Heterotropic co-operative effects between amino acid substrates of phenylalanine hydroxylase.
    The Biochemical journal, 1971, Volume: 123, Issue:4

    Topics: Binding Sites; Carbon Isotopes; Fluorine; Kinetics; Mixed Function Oxygenases; Models, Chemical; Phenylalanine; Phenylalanine Hydroxylase; Tryptophan

1971
Inhibition of serotonin biosynthesis by 6-halotryptophans in vivo.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carbon Radioisotopes; Carboxy-Lyases; Catechol O-Methyltransferase; Catecholamines; Catechols; Dopamine; Female; Fluorine; Hydroxyindoleacetic Acid; Ileum; In Vitro Techniques; Intestinal Mucosa; Kidney; Lung; Male; Metabolism; Methyltransferases; Mixed Function Oxygenases; Monoamine Oxidase; Myocardium; Norepinephrine; Pargyline; Rats; Serotonin; Spleen; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1971
The subunit structure of jack-bean urease.
    The Biochemical journal, 1969, Volume: 113, Issue:4

    Topics: Amino Acid Sequence; Carboxypeptidases; Detergents; Electrophoresis; Fluorine; Hydrazines; Methionine; Molecular Weight; Nitrobenzenes; Plants; Pyrrolidinones; Sulfuric Acids; Thiocyanates; Trypsin; Tryptophan; Urease

1969
Studies on human somatotropin. Preparation and some physico-chemical properties.
    International journal of protein research, 1969, Volume: 1, Issue:2

    Topics: Amino Acid Sequence; Amino Acids; Ammonium Sulfate; Animals; Biological Assay; Body Weight; Carboxypeptidases; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Paper; Disulfides; Electrophoresis; Electrophoresis, Disc; Female; Fluorine; Formates; Freeze Drying; Growth Hormone; Humans; Hydrogen-Ion Concentration; Hypophysectomy; Isoflurophate; Macromolecular Substances; Molecular Weight; Nitrobenzenes; Oxidation-Reduction; Polarography; Polymers; Rats; Spectrophotometry; Tryptophan; Tyrosine; Ultraviolet Rays; Urea

1969
Near-ultraviolet absorption bands of tryptophan. Studies using indole and 3-methylindole as models.
    Biochemistry, 1970, Dec-08, Volume: 9, Issue:25

    Topics: Chemical Phenomena; Chemistry; Cyclohexanes; Fluorescence; Fluorine; Hydrocarbons, Halogenated; Indoles; Models, Chemical; Solvents; Spectrophotometry; Tryptophan; Ultraviolet Rays

1970
Biosynthesis of pyrrolnitrins by analogue-resistant mutants of Pseudomonas fluorescens.
    Folia microbiologica, 1971, Volume: 16, Issue:3

    Topics: Antifungal Agents; Biological Assay; Carbon Isotopes; Chemical Phenomena; Chemistry; Culture Media; Drug Resistance, Microbial; Fermentation; Fluorine; Genetics, Microbial; Mutation; Neurospora; Nitrophenols; Pseudomonas; Pyrroles; Stereoisomerism; Tryptophan

1971
Preparation of substituted phenyl pyrroles through the metabolism of tryptophan analogues.
    Biochemical and biophysical research communications, 1968, May-10, Volume: 31, Issue:3

    Topics: Antifungal Agents; Biological Assay; Fermentation; Fluorine; Magnetic Resonance Spectroscopy; Pseudomonas; Pyrroles; Spectrum Analysis; Tryptophan

1968
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 128, Issue:1

    Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine

1968
Phenylalanine hydroxylase activity towards two substrates simultaneously: enhancement of inhibition by phenylalanine, tryptophan and their derivatives.
    Biochimica et biophysica acta, 1968, Aug-27, Volume: 167, Issue:1

    Topics: Animals; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Fluorine; Fluorometry; Kinetics; Liver; Mixed Function Oxygenases; Phenylalanine; Pteridines; Rats; Tryptophan

1968
[On the glycyl-glycine dipeptidase (EC 3.4.3.1) from porcine erythrocytes].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1968, Volume: 349, Issue:11

    Topics: Animals; Benzene Derivatives; Cadmium; Caproates; Chloromercuribenzoates; Chromatography, Gel; Chromatography, Ion Exchange; Cobalt; Dipeptidases; Enzyme Activation; Erythrocytes; Fluorine; Histidine; Imidazoles; Indoleacetic Acids; Indoles; Leucine; Manganese; Mercury; Silver; Sulfones; Swine; Tryptophan; Zinc

1968
Fluorine-19 nuclear magnetic resonance study of 5-fluorotryptophan-labeled histidine-binding protein J of Salmonella typhimurium.
    Journal of molecular biology, 1984, Nov-15, Volume: 179, Issue:4

    Topics: Carrier Proteins; Fluorine; Histidine; Magnetic Resonance Spectroscopy; Mathematics; Periplasmic Binding Proteins; Protein Conformation; Salmonella typhimurium; Spectrometry, Fluorescence; Temperature; Tryptophan

1984
Stopped-flow NMR spectroscopy: real-time unfolding studies of 6-19F-tryptophan-labeled Escherichia coli dihydrofolate reductase.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Sep-26, Volume: 92, Issue:20

    Topics: Circular Dichroism; Escherichia coli; Fluorine; Kinetics; Magnetic Resonance Spectroscopy; Protein Conformation; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase; Tryptophan

1995
Fluorine-19 nuclear magnetic resonance spectroscopic study of fluorophenylalanine- and fluorotryptophan-labeled avian egg white lysozymes.
    Biochemistry, 1994, May-03, Volume: 33, Issue:17

    Topics: Amino Acid Sequence; Animals; Chickens; Female; Fluorine; Guanidine; Guanidines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muramidase; Mutagenesis, Site-Directed; p-Fluorophenylalanine; Phenylalanine; Protein Conformation; Protein Denaturation; Quail; Recombinant Proteins; Tryptophan

1994
A 19F-NMR study of the membrane-binding region of D-lactate dehydrogenase of Escherichia coli.
    Protein science : a publication of the Protein Society, 1993, Volume: 2, Issue:11

    Topics: DNA Mutational Analysis; Escherichia coli; Fluorine; Kinetics; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Magnetic Resonance Spectroscopy; Membranes, Artificial; Mutagenesis, Site-Directed; Spin Labels; Tryptophan; Tyrosine

1993
19F NMR relaxation studies on 5-fluorotryptophan- and tetradeutero-5-fluorotryptophan-labeled E. coli glucose/galactose receptor.
    Journal of biomolecular NMR, 1996, Volume: 7, Issue:4

    Topics: Anisotropy; Deuterium; Escherichia coli; Fluorine; Magnetic Resonance Spectroscopy; Receptors, Cell Surface; Tryptophan

1996
A 19F-NMR study of the equilibrium unfolding of membrane-associated D-lactate dehydrogenase of Escherichia coli.
    Biochemistry, 1996, Dec-24, Volume: 35, Issue:51

    Topics: Circular Dichroism; Detergents; Escherichia coli; Fluorine; Guanidine; Guanidines; L-Lactate Dehydrogenase; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Membranes; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Solvents; Spectrometry, Fluorescence; Tryptophan

1996
Real-time refolding studies of 6-19F-tryptophan labeled Escherichia coli dihydrofolate reductase using stopped-flow NMR spectroscopy.
    Biochemistry, 1996, Dec-24, Volume: 35, Issue:51

    Topics: Circular Dichroism; Escherichia coli; Fluorine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrophotometry; Tetrahydrofolate Dehydrogenase; Tryptophan

1996
Effects of fluorine substitution on the structure and dynamics of complexes of dihydrofolate reductase (Escherichia coli).
    Biophysical journal, 1997, Volume: 73, Issue:3

    Topics: Amides; Amino Acid Sequence; Binding Sites; Computer Simulation; Escherichia coli; Fluorine; Folic Acid; Ligands; Magnetic Resonance Spectroscopy; Methotrexate; Models, Chemical; Models, Structural; Protein Binding; Protein Conformation; Protein Structure, Secondary; Software; Tetrahydrofolate Dehydrogenase; Time Factors; Tryptophan

1997
Refolding of [6-19F]tryptophan-labeled Escherichia coli dihydrofolate reductase in the presence of ligand: a stopped-flow NMR spectroscopy study.
    Biochemistry, 1998, Jan-06, Volume: 37, Issue:1

    Topics: Circular Dichroism; Escherichia coli; Fluorine; Folic Acid; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; NADP; Protein Folding; Spectrometry, Fluorescence; Tetrahydrofolate Dehydrogenase; Tryptophan

1998
Incorporation of tryptophan analogues into staphylococcal nuclease, its V66W mutant, and Delta 137-149 fragment: spectroscopic studies.
    Biochemistry, 1998, Jun-23, Volume: 37, Issue:25

    Topics: Amino Acid Substitution; Circular Dichroism; Fluorine; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Mutagenesis, Site-Directed; Peptide Fragments; Spectrometry, Fluorescence; Tryptophan; Valine

1998
Noncontact dipole effects on channel permeation. I. Experiments with (5F-indole)Trp13 gramicidin A channels.
    Biophysical journal, 1998, Volume: 75, Issue:6

    Topics: Biophysical Phenomena; Biophysics; Electric Conductivity; Fluorine; Glycerides; Gramicidin; In Vitro Techniques; Indoles; Ion Channels; Kinetics; Lipid Bilayers; Membrane Potentials; Models, Chemical; Molecular Conformation; Onium Compounds; Permeability; Thermodynamics; Tryptophan

1998
The role of beta-Arg-182, an essential catalytic site residue in Escherichia coli F1-ATPase.
    Biochemistry, 1999, Jun-15, Volume: 38, Issue:24

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Escherichia coli; Fluorine; Glutamine; Lysine; Mutagenesis, Site-Directed; Proton-Translocating ATPases; Spectrometry, Fluorescence; Tryptophan

1999
Importance of F1-ATPase residue alpha-Arg-376 for catalytic transition state stabilization.
    Biochemistry, 1999, Nov-23, Volume: 38, Issue:47

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Arginine; Binding Sites; Catalysis; Cysteine; Enzyme Stability; Escherichia coli; Fluorine; Glutamine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Proton-Translocating ATPases; Spectrometry, Fluorescence; Tryptophan; Tyrosine

1999
Probing local environments of tryptophan residues in proteins: comparison of 19F nuclear magnetic resonance results with the intrinsic fluorescence of soluble human tissue factor.
    Proteins, 1999, Dec-01, Volume: 37, Issue:4

    Topics: Circular Dichroism; Crystallography, X-Ray; Fluorine; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thromboplastin; Tryptophan

1999
Conformational changes in the human estrogen receptor observed by (19)F NMR.
    Biochemical and biophysical research communications, 2000, Apr-21, Volume: 270, Issue:3

    Topics: Binding Sites; Estradiol; Fluorine; Glutathione Transferase; Humans; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Receptors, Estrogen; Recombinant Fusion Proteins; Tryptophan

2000
19F NMR investigation of F(1)-ATPase of Escherichia coli using fluorotryptophan labeling.
    Journal of biochemistry, 2000, Volume: 127, Issue:6

    Topics: 4-Chloro-7-nitrobenzofurazan; Carboxypeptidases; Dimethylamines; Escherichia coli; Fluorine; Glycine; Glyphosate; Magnetic Resonance Spectroscopy; Proton-Translocating ATPases; Tryptophan

2000
Noncontact dipole effects on channel permeation. V. Computed potentials for fluorinated gramicidin.
    Biophysical journal, 2001, Volume: 81, Issue:3

    Topics: Binding Sites; Cell Membrane Permeability; Fluorine; Gramicidin; Hydrogen Bonding; Ion Channels; Membrane Potentials; Protein Conformation; Rotation; Static Electricity; Thermodynamics; Tryptophan; Water

2001
Real-time and equilibrium (19)F-NMR studies reveal the role of domain-domain interactions in the folding of the chaperone PapD.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Jan-22, Volume: 99, Issue:2

    Topics: Bacterial Proteins; Biophysical Phenomena; Biophysics; Circular Dichroism; Escherichia coli; Escherichia coli Proteins; Fluorine; Humans; Magnetic Resonance Spectroscopy; Molecular Chaperones; Mutagenesis, Site-Directed; Periplasmic Proteins; Protein Folding; Protein Structure, Tertiary; Tryptophan; Urea

2002
Placement of 19F into the center of GB1: effects on structure and stability.
    FEBS letters, 2002, Apr-24, Volume: 517, Issue:1-3

    Topics: Bacterial Proteins; Circular Dichroism; Fluorine; Hemodynamics; Immunoglobulin G; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis; Mutation; Protein Conformation; Protein Denaturation; Protein Structure, Tertiary; Streptococcus; Thermodynamics; Tryptophan

2002
Role of entropy in protein thermostability: folding kinetics of a hyperthermophilic cold shock protein at high temperatures using 19F NMR.
    Biochemistry, 2002, Oct-01, Volume: 41, Issue:39

    Topics: Bacterial Proteins; Calorimetry, Differential Scanning; Carrier Proteins; Entropy; Fluorine; Guanidine; Heat-Shock Proteins; Hot Temperature; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Spectrophotometry; Thermotoga maritima; Tryptophan

2002
Noncontact dipole effects on channel permeation. VI. 5F- and 6F-Trp gramicidin channel currents.
    Biophysical journal, 2002, Volume: 83, Issue:4

    Topics: Algorithms; Biophysical Phenomena; Biophysics; Cell Membrane Permeability; Computer Simulation; Electric Conductivity; Fluorine; Gramicidin; Ion Channels; Ion Transport; Kinetics; Lipid Bilayers; Membrane Potentials; Models, Chemical; Potassium; Sodium; Static Electricity; Tryptophan

2002
Use of selective Trp side chain labeling to characterize protein-protein and protein-ligand interactions by NMR spectroscopy.
    Journal of the American Chemical Society, 2003, Mar-12, Volume: 125, Issue:10

    Topics: Carbon Isotopes; Escherichia coli; Fluorine; Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; Proteins; Recombinant Proteins; Tryptophan; X-Linked Inhibitor of Apoptosis Protein

2003
Selective incorporation of 19F-labeled Trp side chains for NMR-spectroscopy-based ligand-protein interaction studies.
    Chembiochem : a European journal of chemical biology, 2003, Jul-07, Volume: 4, Issue:7

    Topics: Escherichia coli; Escherichia coli Proteins; Fluorine; Hydrocarbons, Fluorinated; Indoles; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Recombinant Proteins; Tryptophan

2003
(19)F NMR studies of the leucine-isoleucine-valine binding protein: evidence that a closed conformation exists in solution.
    Journal of biomolecular structure & dynamics, 2003, Volume: 21, Issue:2

    Topics: Bacterial Proteins; Carrier Proteins; Escherichia coli Proteins; Fluorine; Mathematics; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Solutions; Tryptophan

2003
REQUIREMENT FOR P-FLUOROPHENYLALANINE ACTIVATION IN CONTROL OF RIBONUCLEIC ACID SYNTHESIS.
    Biochimica et biophysica acta, 1965, Jan-11, Volume: 95

    Topics: Carbon Isotopes; Escherichia coli; Feedback; Fluorides; Fluorine; Ligases; Metabolism; Mutation; p-Fluorophenylalanine; Pharmacology; Phenylalanine; Radiometry; Research; RNA; RNA, Bacterial; Shikimic Acid; Tryptophan; Tyrosine

1965
Urea-dependent unfolding of murine adenosine deaminase: sequential destabilization as measured by 19F NMR.
    Biochemistry, 2004, Feb-17, Volume: 43, Issue:6

    Topics: Adenosine Deaminase; Animals; Circular Dichroism; Enzyme Stability; Fluorine; Magnetic Resonance Spectroscopy; Mice; Mutagenesis, Site-Directed; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tryptophan; Urea

2004
19F NMR studies of plasminogen activator inhibitor-1.
    Biochemistry, 2004, Feb-17, Volume: 43, Issue:6

    Topics: Fluorine; Humans; Hydrolysis; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Plasminogen Activator Inhibitor 1; Recombinant Proteins; Serine Proteinase Inhibitors; Structure-Activity Relationship; Tissue Plasminogen Activator; Tryptophan

2004
Quantitation of protein expression in a cell-free system: Efficient detection of yields and 19F NMR to identify folded protein.
    Journal of biomolecular NMR, 2005, Volume: 31, Issue:1

    Topics: Fluorine; Humans; Magnetic Resonance Spectroscopy; Proteins; Retinol-Binding Proteins; Tryptophan

2005
Interaction of the eukaryotic pore-forming cytolysin equinatoxin II with model membranes: 19F NMR studies.
    Journal of molecular biology, 2005, Mar-18, Volume: 347, Issue:1

    Topics: Animals; Cattle; Cell Membrane; Cnidarian Venoms; Cytotoxins; Fluorine; Hemolysis; Micelles; Models, Molecular; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Tertiary; Sea Anemones; Sphingomyelins; Tryptophan; Vasoconstrictor Agents

2005
Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies.
    Protein science : a publication of the Protein Society, 2005, Volume: 14, Issue:9

    Topics: Amides; Amino Acid Substitution; Base Sequence; Escherichia coli; Fluorine; Humans; Isotopes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Myocardium; Nitrogen; Phenylalanine; Protein Conformation; Protein Folding; Protons; Recombinant Proteins; Solutions; Troponin C; Tryptophan

2005
A residual structure in unfolded intestinal fatty acid binding protein consists of amino acids that are neighbors in the native state.
    Biochemistry, 2006, Feb-28, Volume: 45, Issue:8

    Topics: Amino Acids; Circular Dichroism; Fatty Acid-Binding Proteins; Fluorescence; Fluorine; Hydrophobic and Hydrophilic Interactions; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Tryptophan; Tyrosine; Urea

2006
Alpha-synuclein structures probed by 5-fluorotryptophan fluorescence and 19F NMR spectroscopy.
    The journal of physical chemistry. B, 2006, Apr-06, Volume: 110, Issue:13

    Topics: alpha-Synuclein; Fluorescence; Fluorine; Isotopes; Magnetic Resonance Spectroscopy; Tryptophan

2006
Tryptophan solvent exposure in folded and unfolded states of an SH3 domain by 19F and 1H NMR.
    Biochemistry, 2006, Nov-28, Volume: 45, Issue:47

    Topics: Fluorine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protons; Solvents; Thermodynamics; Tryptophan

2006
Comparison of C40/82A and P27A C40/82A barstar mutants using 19F NMR.
    Biochemistry, 2007, Apr-10, Volume: 46, Issue:14

    Topics: Bacterial Proteins; Dose-Response Relationship, Drug; Fluorine; Hydrophobic and Hydrophilic Interactions; Motion; Mutation; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Temperature; Tryptophan; Ultracentrifugation; Urea

2007
Side-chain conformation of the M2 transmembrane peptide proton channel of influenza a virus from 19F solid-state NMR.
    The journal of physical chemistry. B, 2007, Sep-13, Volume: 111, Issue:36

    Topics: Fluorine; Hydrogen-Ion Concentration; Influenza A virus; Ion Channels; Magnetic Resonance Spectroscopy; Peptides; Protein Conformation; Protons; Tryptophan; Viral Matrix Proteins

2007
Long-range 19F-15N distance measurements in highly-13C, 15N-enriched solid proteins with 19F-dephased REDOR shift (FRESH) spectroscopy.
    Magnetic resonance in chemistry : MRC, 2007, Volume: 45 Suppl 1

    Topics: Carbon Isotopes; Fluorine; Isotope Labeling; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Tryptophan

2007
Solid-state 19F NMR spectroscopy reveals that Trp41 participates in the gating mechanism of the M2 proton channel of influenza A virus.
    Journal of the American Chemical Society, 2008, Jan-23, Volume: 130, Issue:3

    Topics: Fluorine; Histidine; Humans; Hydrogen-Ion Concentration; Ion Transport; Isotopes; Membrane Proteins; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Tryptophan; Viral Matrix Proteins

2008
5-fluorotryptophan as dual probe for ground-state heterogeneity and excited-state dynamics in apoflavodoxin.
    FEBS letters, 2009, Sep-03, Volume: 583, Issue:17

    Topics: Apoproteins; Azotobacter vinelandii; Flavodoxin; Fluorescence Polarization; Fluorine; Magnetic Resonance Spectroscopy; Nuclear Magnetic Resonance, Biomolecular; Tryptophan

2009
Calculation of fluorine chemical shift tensors for the interpretation of oriented (19)F-NMR spectra of gramicidin A in membranes.
    Physical chemistry chemical physics : PCCP, 2009, Aug-28, Volume: 11, Issue:32

    Topics: Cell Membrane; Fluorine; Gramicidin; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Quantum Theory; Time Factors; Tryptophan

2009
Asymmetric Mannich reaction of fluorinated ketoesters with a tryptophan-derived bifunctional thiourea catalyst.
    Angewandte Chemie (International ed. in English), 2009, Volume: 48, Issue:41

    Topics: Catalysis; Esters; Fluorine; Ketones; Molecular Conformation; Molecular Structure; Thiourea; Tryptophan

2009
Rapid acquisition of 1H and 19F NMR experiments for direct and competition ligand-based screening.
    Magnetic resonance in chemistry : MRC, 2011, Volume: 49, Issue:4

    Topics: Binding, Competitive; Fluorine; Humans; Ligands; Magnetic Resonance Spectroscopy; Protons; Serum Albumin; Solubility; Tryptophan

2011
Simple and inexpensive incorporation of 19F-tryptophan for protein NMR spectroscopy.
    Chemical communications (Cambridge, England), 2012, Nov-07, Volume: 48, Issue:86

    Topics: Escherichia coli; Fluorine; Indoles; Nuclear Magnetic Resonance, Biomolecular; Proteins; Tryptophan

2012
19F NMR as a probe of ligand interactions with the iNOS binding site of SPRY domain-containing SOCS box protein 2.
    Chemical biology & drug design, 2014, Volume: 84, Issue:5

    Topics: Binding Sites; Carrier Proteins; Fluorine; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Nitric Oxide Synthase Type II; Peptides; Protein Conformation; Surface Plasmon Resonance; Tryptophan

2014
Atomic basis for therapeutic activation of neuronal potassium channels.
    Nature communications, 2015, Sep-03, Volume: 6

    Topics: Animals; Anticonvulsants; Carbamates; Fluorine; Humans; Hydrogen Bonding; KCNQ Potassium Channels; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Molecular Docking Simulation; Mutagenesis, Site-Directed; Neurons; Oocytes; Patch-Clamp Techniques; Phenylenediamines; Tryptophan; Xenopus laevis

2015
An artificial self-sufficient cytochrome P450 directly nitrates fluorinated tryptophan analogs with a different regio-selectivity.
    Biotechnology journal, 2016, Volume: 11, Issue:5

    Topics: Binding Sites; Biocatalysis; Cytochrome P-450 Enzyme System; Fluorine; Indoles; Nitrates; Protein Domains; Protein Engineering; Recombinant Fusion Proteins; Tandem Mass Spectrometry; Tryptophan

2016
    The journal of physical chemistry. B, 2018, 06-14, Volume: 122, Issue:23

    Topics: Density Functional Theory; Fluorine; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Tryptophan

2018
Identification of biosynthetic genes for the β-carboline alkaloid kitasetaline and production of the fluorinated derivatives by heterologous expression.
    Journal of industrial microbiology & biotechnology, 2019, Volume: 46, Issue:5

    Topics: Acetylcysteine; Alkaloids; Amidohydrolases; Carbolines; Cell Line, Tumor; Fluorine; Humans; Multigene Family; Mutation; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Streptomyces; Tryptophan

2019
    Journal of biomolecular NMR, 2019, Volume: 73, Issue:8-9

    Topics: Cyclophilins; Fluorine; Indoles; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Tryptophan

2019
Ex Vivo Analysis of Tryptophan Metabolism Using
    ACS chemical biology, 2019, 09-20, Volume: 14, Issue:9

    Topics: Animals; Female; Fluorine; Gastrointestinal Microbiome; Magnetic Resonance Spectroscopy; Male; Proof of Concept Study; Rats, Sprague-Dawley; Tryptophan

2019
What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein.
    Scientific reports, 2020, 02-14, Volume: 10, Issue:1

    Topics: Bacillus subtilis; Bacterial Proteins; Crystallography, X-Ray; Fluorine; Halogenation; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Conformation; Protein Stability; Thermodynamics; Tryptophan

2020
Synthesis and Preclinical Evaluation of 6-[
    ACS chemical neuroscience, 2020, 06-17, Volume: 11, Issue:12

    Topics: Animals; Fluorine; Kynurenine; Mice; Positron-Emission Tomography; Radiopharmaceuticals; Tryptophan

2020
Soluble Methane Monooxygenase Component Interactions Monitored by
    Biochemistry, 2021, 06-29, Volume: 60, Issue:25

    Topics: Bacterial Proteins; Fluorine; Kinetics; Methylosinus trichosporium; Nuclear Magnetic Resonance, Biomolecular; Oxygenases; Protein Binding; Protein Structure, Quaternary; Protein Subunits; Tryptophan

2021
Site-Specific Incorporation of 7-Fluoro-L-tryptophan into Proteins by Genetic Encoding to Monitor Ligand Binding by
    ACS sensors, 2022, 01-28, Volume: 7, Issue:1

    Topics: Fluorine; Humans; Hydrogen; Ligands; Magnetic Resonance Spectroscopy; Proteins; Tryptophan; Zika Virus; Zika Virus Infection

2022
Assessing the applicability of
    Journal of biomolecular NMR, 2023, Volume: 77, Issue:1-2

    Topics: Fluorine; Fluorine Radioisotopes; Nuclear Magnetic Resonance, Biomolecular; Proteins; Protons; Tryptophan

2023