tryptophan has been researched along with fluorine in 111 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 56 (50.45) | 18.7374 |
1990's | 16 (14.41) | 18.2507 |
2000's | 25 (22.52) | 29.6817 |
2010's | 9 (8.11) | 24.3611 |
2020's | 5 (4.50) | 2.80 |
Authors | Studies |
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Birdsall, B; Burgen, AS; Feeney, J; Griffiths, DV; Kimber, BJ; Roberts, GC; Sykes, BD | 1 |
Harada, M; Kido, R; Koga, K; Miura, I; Nishitani, H | 1 |
Falke, JJ; Luck, LA | 1 |
d'Avignon, A; Gordon, JI; Li, E; Qian, SJ; Yang, NC | 1 |
Everett, MM | 1 |
Sahm, U | 1 |
Johnson, RW; Kenney, FT | 1 |
Favorova, OO; Kochkina, LL; Lavrik, OI; Nevinsky, GA; Petrova, TD; Savchenko, TI | 1 |
Godfrey, OW | 1 |
Udenfriend, S | 1 |
Hrdina, PD; Ling, GM; Peters, DA; Singhal, RL | 1 |
Peters, DA | 2 |
Crewther, P; Davidson, BE; Dopheide, TA | 1 |
Eubanks, EE; Jacobs, BL; Wise, WD | 1 |
Oswald, I | 1 |
Feigelson, P; Koike, K | 2 |
Beck, CF; Ingraham, JL; Kleker, E; Neuhard, J; Thomassen, E | 1 |
Cihak, A; Pitot, HC; Wilkinson, D | 1 |
Kuhn, JC; Pabst, MJ; Somerville, RL | 1 |
Peralta, EG; Segura, J | 1 |
Widholm, JM | 2 |
Kumbar, M; Sankar, DV | 1 |
Goldberg, AL; Prouty, WF | 2 |
Collins, JS; Packter, NM | 1 |
Wilcox, M | 1 |
Coy, DH; Coy, EJ; Hirotsu, Y; Schally, AV; Tesser, GI; van Nispen, JW; Vilchez-Martinez, JA | 1 |
Bosin, TR; Hall, LE; Hegeman, GD | 1 |
Calhoun, DH; Jensen, RA | 1 |
Hartley, R; Smith, JA | 1 |
Costa, E; Löfstrandh, S; Morgan, D | 1 |
Cottrall, MF; Taylor, DM | 1 |
Brady, FO; Feigelson, P | 1 |
Dorrington, KJ; Hofmann, T | 1 |
Wells, MA | 1 |
Herskovits, TT; Solli, NJ | 1 |
Hrdina, PD; Peters, DA; Singhal, RL | 1 |
Browne, DR; Hegeman, GD; Kenyon, GL | 1 |
Feigelson, P; Forman, HJ | 1 |
Ericsson, LH; Hermodson, MA; Neurath, H; Titani, K; Walsh, KA | 1 |
Billups, C; Kay, E; Strickland, EH | 1 |
Costa, E; Groppetti, A; Misher, A; Naimzada, M; Revuelta, A | 1 |
Atkins, HL; Christman, DR; Fowler, JS; Hauser, W; Hoyte, RM; Klopper, JF; Lin, SS; Wolf, AP | 1 |
Gerig, JT; Rimerman, RA | 1 |
Horton, HR; Naik, VR | 1 |
Coulson, WF; Hughes, CM | 1 |
Bailey, CJ; Boulter, D | 1 |
Fonss-Bech, P; Schmidt, KD | 1 |
Billups, C; Horwitz, J; Strickland, EH | 1 |
Elander, RP; Gorman, M; Hamill, RL; Mabe, JA | 1 |
Elander, RP; Gorman, M; Hamill, RL; Mabe, J | 1 |
Brown, JH; Mackey, HK | 1 |
Coulson, WF; Jepson, JB; Wardle, E | 1 |
Bidlingmaier, F; Schneider, F | 1 |
Cottam, PF; Ho, C; Post, JF; Simplaceanu, V | 1 |
Frieden, C; Hoeltzli, SD | 3 |
Harrell, S; Laws, D; Le, H; Lian, C; Matsumura, I; Montez, B; Oldfield, E; Patterson, J; Pearson, J | 1 |
Groetsch, SM; Ho, C; Homer, RJ; Hsue, PY; Kulig, CE; Pratt, EA; Sun, ZY; Sutherland, DC; Truong, HT | 1 |
London, RE; Luck, LA; O'Connell, TM; Vance, JE | 1 |
Ho, C; Pratt, EA; Simplaceanu, V; Sun, ZY | 1 |
Gerig, JT; Lau, EY | 1 |
Eftink, MR; Wong, CY | 1 |
Baird, LC; Bingham, NC; Busath, DD; Cole, CD; Cotten, M; Cross, TA; Hendershot, RJ; Hendershot, RW; Maughan, P; Morrison, S; Phillips, LR; Thulin, CD | 1 |
Nadanaciva, S; Senior, AE; Weber, J | 1 |
Nadanaciva, S; Senior, AE; Weber, J; Wilke-Mounts, S | 1 |
Luck, LA; Nemerson, Y; Ross, JB; Rusinova, E; Zemsky, J | 1 |
Barse, JL; Luck, AM; Luck, LA; Peck, CH | 1 |
Choi, JW; Jung, S; Kim, HW; Lee, HW; Sohn, JH; Yeh, BI | 1 |
Anderson, DG; Busath, DD; Cross, TA; Shirts, RB | 1 |
Bann, JG; Frieden, C; Hultgren, SJ; Pinkner, J | 1 |
Aziz, R; Campos-Olivas, R; Evans, JN; Gronenborn, AM; Helms, GL | 1 |
Jaenicke, R; Kalbitzer, HR; Kremer, W; Schuler, B | 1 |
Busath, DD; Cole, CD; Cotten, M; Cross, TA; Frost, AS; Thompson, N | 1 |
Pellecchia, M; Rodriguez-Mias, RA | 1 |
Leone, M; Pellecchia, M; Rodriguez-Mias, RA | 1 |
Honek, JF; Luck, LA; Salopek-Sondi, B; Skeels, MC; Vaughan, MD | 1 |
EZEKIEL, DH | 1 |
Frieden, C; Shu, Q | 1 |
Abbott, GL; Blouse, GE; Luck, LA; Perron, MJ; Shore, JD; Szabo, AG | 1 |
Campbell, ID; Colebrooke, SA; Greene, LH; Neerathilingam, M; Staunton, D | 1 |
Anderluh, G; Macek, P; Norton, RS; Podlesek, Z; Razpotnik, A; Separovic, F | 1 |
Letourneau, PJ; Mercier, P; Sykes, BD; Wang, X | 1 |
Boyer, JA; Dalessio, PM; Ropson, IJ | 1 |
Gray, HB; Harkins, SB; Lee, JC; Winkler, GR | 1 |
Bezsonova, I; Evanics, F; Forman-Kay, JD; Kitevski, JL; Marsh, J; Prosser, RS | 1 |
Frieden, C; Li, H | 1 |
Hong, M; Luo, W; Mani, R | 1 |
Franks, WT; Graesser, DT; Nieuwkoop, AJ; Rienstra, CM; Wylie, BJ | 1 |
Cross, TA; Fu, R; Nozirov, F; Sternberg, U; Ulrich, AS; Witter, R | 1 |
Broos, J; Nabuurs, SM; van Amerongen, H; van Hoek, A; van Mierlo, CP; Visser, AJ; Visser, NV; Westphal, AH | 1 |
Grage, SL; Klipfel, M; Sternberg, U; Ulrich, AS; Witter, R | 1 |
Han, X; Huang, KW; Kwiatkowski, J; Lu, Y; Xue, F | 1 |
Coutant, J; Dalvit, C; Gossert, AD; Piotto, M | 1 |
Crowley, PB; Kyne, C; Monteith, WB | 1 |
Baell, JB; Harjani, JR; Leung, EW; Mulcair, MD; Norton, RS; Scanlon, MJ; Yagi, H | 1 |
Ahern, CA; Galpin, JD; Kim, RY; Kurata, HT; Pless, SA; Seebohm, G; Yau, MC | 1 |
Bruner, SD; Dedic, E; Ding, Y; Huguet-Tapia, JC; Loria, R; Mehta, M; Zhang, Y; Zuo, R | 1 |
Bai, S; Dybowski, C; Fritz, M; Gronenborn, AM; Holmes, ST; Kraus, J; Lu, M; Maas, W; Polenova, T; Quinn, CM; Sarkar, S; Sergeyev, IV; Struppe, J; Wang, M; Yap, GPA | 1 |
Arai, M; Ikeda, H; Ikejiri, Y; Kitani, S; Namba, T; Nihira, T; Nishimoto, Y; Ueda, S | 1 |
Gronenborn, AM; Ishima, R; Lu, M; Polenova, T | 1 |
Dunlap, LE; Olson, DE; Saunders, CM; Tantillo, DJ; Tombari, RJ; Wu, CY | 1 |
Kovermann, M; Mayans, O; Mihajlenko, X; Welte, H; Zhou, T | 1 |
Avagliano, C; Cervenka, S; Erhardt, S; Häggkvist, J; Johnström, P; Kondrashov, M; Krasikova, R; Petukhov, M; Revunov, E; Schou, M; Tari, L; Tóth, M; Vazquez-Romero, A | 1 |
Aihara, H; Banerjee, R; Jones, JC; Lipscomb, JD; Pomerantz, WCK; Semonis, MM; Shi, K | 1 |
Abdelkader, EH; Herath, ID; Huber, T; Otting, G; Qianzhu, H | 1 |
Krempl, C; Sprangers, R | 1 |
2 review(s) available for tryptophan and fluorine
Article | Year |
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Arene oxide intermediates in enzymatic hydroxylation and their significance with respect to drug toxicity.
Topics: Acetanilides; Amphetamine; Bromine; Chemical Phenomena; Chemistry; Chlorine; Deuterium; Ethers, Cyclic; Fenclonine; Fluorine; Glutathione; Mixed Function Oxygenases; Naphthalenes; Phenols; Phenylalanine; Phenylpyruvic Acids; Tritium; Tryptophan | 1971 |
The effect of pyrimidine analogues and tryptophan on enzyme synthesis and degradation in rat liver.
Topics: Adrenalectomy; Animals; Carbon Isotopes; Caseins; Centrifugation, Density Gradient; Cortisone; Cytidine; Dactinomycin; Enzyme Induction; Fluorine; L-Serine Dehydratase; Leucine; Liver; Lyases; Male; Nucleoproteins; Nucleosides; Ornithine; Orotic Acid; Phenylpyruvic Acids; Protein Hydrolysates; Pyrimidines; Rats; Ribosomes; RNA; Time Factors; Transaminases; Triazines; Tritium; Tryptophan; Tryptophan Oxygenase; Tyrosine Transaminase | 1970 |
109 other study(ies) available for tryptophan and fluorine
Article | Year |
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Proximity of two tryptophan residues in dihydrofolate reductase determined by 19f NMR.
Topics: Fluorine; Magnetic Resonance Spectroscopy; Protein Conformation; Tetrahydrofolate Dehydrogenase; Tryptophan | 1978 |
In vivo 19F MR spectroscopic study of metabolism of 5-fluorotryptophan in rat liver.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Fluorine; Liver; Liver Diseases; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Inbred Strains; Tryptophan | 1992 |
Open conformation of a substrate-binding cleft: 19F NMR studies of cleft angle in the D-galactose chemosensory receptor.
Topics: Amino Acid Sequence; Binding Sites; Computer Graphics; Edetic Acid; Escherichia coli; Fluorine; Gadolinium; Galactose; Glucose; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Organometallic Compounds; Protein Conformation; Receptors, Cell Surface; Tryptophan | 1991 |
19F nuclear magnetic resonance studies of 6-fluorotryptophan-substituted rat cellular retinol binding protein II produced in Escherichia coli. An analysis of four tryptophan substitution mutants and their interactions with all-trans-retinol.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Escherichia coli; Fluorine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Protein Binding; Rats; Recombinant Proteins; Retinol-Binding Proteins; Retinol-Binding Proteins, Cellular; Tryptophan; Vitamin A | 1990 |
Deamination by the diazotization-deazotization method.
Topics: Benzene Derivatives; Chemical Phenomena; Chemistry; Connective Tissue; Deamination; Diazonium Compounds; Epithelium; Evaluation Studies as Topic; Fluorine; Gingiva; Histocytochemistry; Humans; Keratins; Lysine; Nitro Compounds; Proteins; Staining and Labeling; Tryptophan; Tyrosine | 1973 |
[The effect of L-2,5-dihydrophenylalanine].
Topics: Aldehyde-Lyases; Anti-Bacterial Agents; Bacterial Proteins; Binding, Competitive; Cyclohexanecarboxylic Acids; Escherichia coli; Feedback; Fluorine; Heptoses; Isoenzymes; Microbial Sensitivity Tests; Oxidoreductases; Phenylalanine; Phosphoenolpyruvate; Protein Biosynthesis; Pyruvates; Tetroses; Tryptophan; Tyrosine | 1972 |
Regulation of tyrosine aminotransferase in rat liver. XI. Studies on the relationship of enzyme stability to enzyme turnover in cultured hepatoma cells.
Topics: Amino Acids; Animals; Antigen-Antibody Reactions; Carbon Isotopes; Carcinoma, Hepatocellular; Catalysis; Cells, Cultured; Culture Media; Drug Stability; Enzyme Induction; Fluorine; Hot Temperature; Hydrocortisone; Liver; Liver Neoplasms; Protein Denaturation; Rabbits; Rats; Structure-Activity Relationship; Tritium; Tryptophan; Tyrosine Transaminase | 1973 |
Fluorinated tryptophans as substrates and inhibitors of the ATP--(32P)PPi exchange reaction catalysed by tryptophanyl tRNA synthetase.
Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Binding, Competitive; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; D-Amino-Acid Oxidase; Diphosphates; Electrophoresis, Polyacrylamide Gel; Fluorine; Kidney; Kinetics; Molecular Weight; Pancreas; Phosphorus Radioisotopes; Protein Binding; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine; Tryptophan; Ultrafiltration | 1974 |
Directed mutation in Streptomyces lipmanii.
Topics: Bacillus subtilis; Biological Assay; Carbon Radioisotopes; Cephalosporins; Cycloserine; DNA Replication; DNA, Bacterial; Fluorine; Genes; Hydrogen-Ion Concentration; Leucine; Mutagens; Mutation; Nitrosoguanidines; Penicillin Resistance; Penicillins; Pseudomonas; Salmonella; Streptomyces; Thymidine; Tritium; Tryptophan | 1974 |
The role of brain serotonin in DDT-induced hyperpyrexia.
Topics: Animals; Brain; Brain Stem; DDT; Fenclonine; Fever; Fluorine; Hydroxyindoleacetic Acid; Male; Pargyline; Rats; Seizures; Serotonin; Tremor; Tryptophan | 1972 |
Inhibition of brain tryptophan-5-hydroxylase by amino acids--the role of L-tryptophan uptake inhibition.
Topics: Animals; Brain; Bromine; Carbon Isotopes; Chlorine; Fenclonine; Fluorine; In Vitro Techniques; Kinetics; Male; Methylation; Mixed Function Oxygenases; Nitro Compounds; Phenylalanine; Rats; Stereoisomerism; Subcellular Fractions; Synaptosomes; Tryptophan | 1972 |
Chorismate mutase-prephenate dehydratase from Escherichia coli K-12. II. Kinetic properties.
Topics: Animals; Benzyl Compounds; Cattle; Chlorine; Cyclohexanecarboxylic Acids; Cyclohexanes; Dithiothreitol; Enzyme Activation; Escherichia coli; Fenclonine; Fluorine; Formates; Hydro-Lyases; Hydrogen-Ion Concentration; Isomerases; Kinetics; Mercaptoethanol; Phenols; Phenylalanine; Propionates; Pyruvates; Serum Albumin, Bovine; Stereoisomerism; Tryptophan | 1972 |
Effect of indolealkylamine manipulations on locomotor activity in rats.
Topics: Amines; Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Diet; Fenclonine; Fluorine; Food Deprivation; Humans; Indoles; Male; Monoamine Oxidase Inhibitors; Motor Activity; Pargyline; Phenoxybenzamine; Propranolol; Rats; Serotonin; Spiro Compounds; Stereotyped Behavior; Stimulation, Chemical; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1974 |
Sleep.
Topics: Amobarbital; Appetite Depressants; Barbiturates; Dreams; Electroencephalography; Fenfluramine; Fluorine; Humans; Methysergide; Narcolepsy; Phenethylamines; Sleep; Sleep Stages; Sleep, REM; Substance-Related Disorders; Time Factors; Tranylcypromine; Tryptophan | 1969 |
Studies on the roles of the catalytic and allosteric sites in modulating the reactivity of tryptophan oxygenase with heme ligands. I. Cyanide derivatives.
Topics: Allosteric Regulation; Binding Sites; Catalysis; Chemical Phenomena; Chemistry, Physical; Cyanides; Electron Spin Resonance Spectroscopy; Fluorine; Guanidines; Heme; Hydrochloric Acid; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Nitriles; Oxidation-Reduction; Peroxidases; Plants; Potassium; Protein Binding; Protein Conformation; Protein Denaturation; Pseudomonas; Spectrophotometry; Sulfites; Tryptophan; Tryptophan Oxygenase | 1971 |
Salmonella typhimurium mutants defective in cytidine monophosphate kinase (cmk).
Topics: Autoradiography; Carbon Radioisotopes; Chromosome Mapping; Cytidine; Cytosine Nucleotides; Deoxycytidine Monophosphate; Fluorine; Genes; Mutagens; Mutation; Nitrosoguanidines; Oxidative Phosphorylation; Phosphorus Radioisotopes; Phosphotransferases; Salmonella typhimurium; Transduction, Genetic; Tryptophan; Ultraviolet Rays; Uridine | 1974 |
Mutant strains of Escherichia coli K-12 exhibiting enhanced sensitivity to 5-methyltryptophan.
Topics: Aspartate-Semialdehyde Dehydrogenase; Aza Compounds; Cell-Free System; Chromosome Mapping; Chromosomes, Bacterial; Drug Resistance, Microbial; Escherichia coli; Feedback; Fluorine; Fluorometry; Glutamine; Methylation; Microbial Sensitivity Tests; Mutation; Operon; ortho-Aminobenzoates; Phosphotransferases; Protein Biosynthesis; Stereoisomerism; Transaminases; Transduction, Genetic; Tryptophan; Tryptophan Synthase | 1972 |
Gas chromatography-mass spectrometry of catecholamines and tryptamines: determination of gas chromatographic profiles of the amines, their precursors and their metabolites.
Topics: Catecholamines; Chromatography, Gas; Fluorine; Indoles; Kinetics; Mass Spectrometry; Methods; Microchemistry; Phenylalanine; Propionates; Tryptamines; Tryptophan | 1974 |
Tryptophan biosynthesis in Nicotiana tabacum and Daucus carota cell cultures: site of action of inhibitory tryptophan analogs.
Topics: 5-Hydroxytryptophan; Acrylates; Cells, Cultured; Cyclohexanecarboxylic Acids; Fluorine; Glycerophosphates; Hydro-Lyases; Indoles; Methylation; Nicotiana; ortho-Aminobenzoates; Plant Development; Plants; Plants, Toxic; Serine; Transaminases; Tryptophan | 1972 |
Cultured Nicotiana tabacum cells with an altered anthranilate synthetase which is less sensitive to feedback inhibition.
Topics: 5-Hydroxytryptophan; Acrylates; Cells, Cultured; Feedback; Fluorine; Indoles; Methylation; Nicotiana; ortho-Aminobenzoates; Plants; Plants, Toxic; Transaminases; Tryptophan | 1972 |
Quantum chemical studies on drug actions. II. Quantum chemical data on derivatives of catechol, indole, imidazole amines and of spermine and spermidine.
Topics: 5-Hydroxytryptophan; Amines; Catecholamines; Catechols; Chemical Phenomena; Chemistry; Dopamine; Epinephrine; Fluorine; Hallucinogens; Histamine; Hydroxyindoleacetic Acid; Hydroxylation; Imidazoles; Indoles; Mandelic Acids; Norepinephrine; Normetanephrine; Phenethylamines; Quantum Theory; Serotonin; Spermidine; Spermine; Sulfhydryl Compounds; Tryptamines; Tryptophan; Tyramine | 1973 |
Effects of protease inhibitors on protein breakdown in Escherichia coli.
Topics: Amidines; Aminobutyrates; Bacterial Proteins; Benzyl Compounds; Canavanine; Chlorine; Culture Media; Enzyme Induction; Escherichia coli; Fluorine; Galactosidases; Hydro-Lyases; Isoflurophate; Leucine; Protease Inhibitors; Serine; Sulfonic Acids; Toluene; Tosyl Compounds; Tritium; Trypsin Inhibitors; Tryptophan | 1972 |
Fate of abnormal proteins in E. coli accumulation in intracellular granules before catabolism.
Topics: Arginine; Aza Compounds; Bacterial Proteins; Canavanine; Carbon Isotopes; Cell Fractionation; Centrifugation, Density Gradient; Escherichia coli; Fluorine; Hydrazones; Leucine; Nitriles; Oxidative Phosphorylation; Phenylhydrazines; Tritium; Tryptophan | 1972 |
Effect of inhibitors of protein synthesis on the formation of phenols derived from acetate and shikimic acid in Aspergillus fumigatus.
Topics: Acetates; Aspergillus fumigatus; Azaguanine; Benzoates; Benzyl Compounds; Culture Media; Cycloheximide; Fluorine; Fungal Proteins; Nitriles; Phenols; Phenylalanine; Phenylpyruvic Acids; Shikimic Acid; Toluene; Tryptophan; Tyrosine | 1974 |
The enzymatic synthesis of L-tryptophan analogues.
Topics: Alcohols; Aza Compounds; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Escherichia coli; Fluorine; Indoles; Isotope Labeling; Methyl Ethers; Phosphatidylcholines; Pyrimidines; Serine; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Tryptophan Synthase | 1974 |
Investigation of the role of tryptophan in the luteinizing hormone-releasing hormone.
Topics: Amino Acids; Amino Acids, Diamino; Animals; Biological Assay; Castration; Dose-Response Relationship, Drug; Electron Transport; Female; Fluorine; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Histidine; Luteinizing Hormone; Male; Nitro Compounds; Phenylalanine; Rats; Sex Factors; Structure-Activity Relationship; Tryptophan | 1974 |
Incorporation of tryptophan and its benzo(b)thiophene, 1-methylindole, and indene analogs into protein of Escherichia coli.
Topics: Bacterial Proteins; Carbon Radioisotopes; Escherichia coli; Fluorine; Galactosidases; Glycerol; Indenes; Indoles; Leucine; Thiophenes; Time Factors; Tritium; Tryptophan | 1974 |
Significance of altered carbon flow in aromatic amino acid synthesis: an approach to the isolation of regulatory mutants in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acids; Biological Assay; Carbon; Cell-Free System; Culture Media; Cyclohexanecarboxylic Acids; Drug Resistance, Microbial; Fluorine; Fluorometry; Fructose; Genetics, Microbial; Hydro-Lyases; Leuconostoc; Methods; Mutation; ortho-Aminobenzoates; Pentosyltransferases; Phenylalanine; Pseudomonas aeruginosa; Transaminases; Tryptophan; Tyrosine | 1972 |
Inhibition of catecholamine oxidation by indoles.
Topics: 5-Hydroxytryptophan; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Dopamine Antagonists; Fluorine; Fungi; Indoles; Kinetics; Melatonin; Monophenol Monooxygenase; Oxidation-Reduction; Serotonin; Spectrophotometry; Tryptamines; Tryptophan | 1972 |
Amphetamine analogues and brain amines.
Topics: Amphetamine; Animals; Biogenic Amines; Brain Chemistry; Brain Stem; Carbon Isotopes; Chlorphentermine; Fluorine; Hydrocarbons, Halogenated; Hypothalamus; Male; Mephentermine; Methamphetamine; Monoamine Oxidase Inhibitors; Norepinephrine; Phenethylamines; Propylamines; Rats; Serotonin; Structure-Activity Relationship; Telencephalon; Tritium; Tryptophan; Tryptophan Hydroxylase; Tyramine | 1972 |
18 F labelled amino acids for pancreas scanning.
Topics: Amino Acids; Animals; Fluorine; Humans; Pancreas; Phenylalanine; Radioisotopes; Radionuclide Imaging; Rats; Tryptophan | 1973 |
Photoactivation of pseudomonad L-tryptophan oxygenase by electron ejection from its substrate, L-tryptophan.
Topics: Allosteric Regulation; Binding Sites; Catalase; Copper; Enzyme Activation; Fluorine; Formates; Kinetics; Methylation; Oxidation-Reduction; Protein Binding; Pseudomonas; Radiation Effects; Spectrophotometry; Superoxide Dismutase; Tryptophan; Tryptophan Oxygenase; Ultraviolet Rays | 1973 |
Effects of ionic strength on the circular dichroism spectrum of chymotrypsin.
Topics: Acetates; Chemical Phenomena; Chemistry; Chlorides; Chymotrypsin; Chymotrypsinogen; Circular Dichroism; Fluorine; Isoleucine; Kinetics; Lithium; Macromolecular Substances; Nitric Oxide; Organophosphonates; Osmolar Concentration; Phosphoric Acids; Sodium; Sodium Chloride; Tryptophan; Ultracentrifugation; Ultraviolet Rays | 1973 |
Effects of chemical modification on the activity of Crotalus adamanteus Phospholipase A 2 . Evidence for an essential amino group.
Topics: Acylation; Amino Acids; Anhydrides; Animals; Binding Sites; Chromatography, Gel; Ethyl Ethers; Fluorine; Formates; Iodine; Iodoacetates; Lysine; Macromolecular Substances; Nitrobenzenes; Oxidation-Reduction; Phospholipases; Protein Conformation; Snakes; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Succinimides; Tryptophan; Urea | 1973 |
Solvent perturbation studies and analysis of protein and model compound data in denaturing organic solvents.
Topics: 1-Propanol; Acetates; Alcohols; Animals; Apoproteins; Cattle; Cetacea; Chlorine; Dimethyl Sulfoxide; Ethanol; Fluorine; Mathematics; Methanol; Methods; Myoglobin; Ovalbumin; Protein Denaturation; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1973 |
Role of noradrenaline, 5-hydroxytryptamine and acetylcholine in the hypothermic and convulsive effects of alpha-chlordane in rats.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Body Temperature; Brain; Brain Chemistry; Brain Stem; Cerebral Cortex; Chlordan; Corpus Striatum; Dose-Response Relationship, Drug; Fluorine; Hindlimb; Hydroxyindoleacetic Acid; Male; Methyltyrosines; Norepinephrine; Paralysis; Rats; Seizures; Serotonin; Time Factors; Tryptophan | 1974 |
Incorporation of monoflurotryptophans into protein during the growth of Escherichia coli.
Topics: Bacterial Proteins; Carbon Isotopes; Depression, Chemical; Escherichia coli; Fluorine; Galactosidases; Glycine; Hydrolases; Microscopy, Phase-Contrast; Mixed Function Oxygenases; Mutation; Tryptophan | 1970 |
The effects of allosteric interaction on the kinetics, spectra, and tertiary structure of pseudomonad tryptophan oxygenase.
Topics: Allosteric Regulation; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Detergents; Drug Stability; Fluorine; Heme; Iron; Kinetics; Oxygen; Protein Binding; Protein Conformation; Pseudomonas; Spectrophotometry; Sulfuric Acids; Tryptophan; Tryptophan Oxygenase; Ultraviolet Rays | 1972 |
Amino acid sequence of thermolysin. Isolation and characterization of the fragments obtained by cleavage with cyanogen bromide.
Topics: Amino Acid Sequence; Amino Acids; Carbohydrates; Carboxypeptidases; Chromatography, Gel; Chromatography, Paper; Cyanates; Cyanogen Bromide; Electrophoresis; Endopeptidases; Fluorine; Guanidines; Isoleucine; Lysine; Molecular Weight; Nitrobenzenes; Sodium Dodecyl Sulfate; Spectrophotometry; Thermolysin; Tryptophan; Tyrosine; Ultraviolet Rays | 1972 |
Effects of hydrogen bonding and solvents upon the tryptophanyl 1 L a absorption band. Studies using 2,3-dimethylindole.
Topics: Acetamides; Acetates; Amides; Butanols; Carboxylic Acids; Chemical Phenomena; Chemistry; Cold Temperature; Cyclohexanes; Fluorine; Histidine; Hydrocarbons, Halogenated; Hydrogen; Imidazoles; Indoles; Methane; Peptides; Proteins; Spectrophotometry; Tryptophan; Ultraviolet Rays | 1972 |
Evidence that in rats 1-benzyl- -methoxy-3-trifluoromethylphenethylamine (SK& F 1-39728) dissociates anorexia from central stimulation and actions on brain monoamine stores.
Topics: Animals; Appetite; Appetite Depressants; Benzyl Compounds; Biogenic Amines; Body Temperature; Brain; Brain Chemistry; Central Nervous System; Dextroamphetamine; Dopamine; Fenfluramine; Fluorine; Kinetics; Male; Motor Activity; Norepinephrine; Phenethylamines; Rats; Rats, Inbred Strains; Serotonin; Stimulation, Chemical; Tritium; Tryptophan; Tyrosine | 1972 |
Organic radiopharmaceuticals labeled with isotopes of short half-life. V. 18 F-labeled 5- and 6-fluorotryptophan.
Topics: Animals; Chemical Phenomena; Chemistry; Dogs; Fluorine; Half-Life; Injections, Intravenous; Isotope Labeling; Liver; Methionine; Methods; Mice; Pancreas; Radioisotopes; Radionuclide Imaging; Rats; Selenium; Tryptophan | 1972 |
Nuclear magnetic resonance studies of the interaction of N-trifluoroacetyltryptophanate with -chymotrypsin.
Topics: Acetates; Chemical Phenomena; Chemistry; Chymotrypsin; Fluorine; Kinetics; Magnetic Resonance Spectroscopy; Tryptophan | 1972 |
Reaction of 2-hydroxy-5-nitrobenzylated carboxypeptidase A with 14 C-1-fluoro-2,4-dinitrobenzene.
Topics: Alanine; Alkylation; Amino Acids; Aspartic Acid; Benzyl Compounds; Carbon Isotopes; Carboxypeptidases; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chromatography, Thin Layer; Dinitrophenols; Fluorine; Fluorometry; Guanidines; Hydrolysis; Nitrobenzenes; Nitrophenols; Protein Denaturation; Serine; Spectrophotometry; Tryptophan; Ultraviolet Rays | 1971 |
Studies on the catalytic and allosteric sites in modulating the reactivity of tryptophan oxygenase with heme ligands. II. Carbon monoxide derivatives.
Topics: Allosteric Regulation; Binding Sites; Carbon Monoxide; Catalysis; Chemical Phenomena; Chemistry; Fluorine; Heme; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Oxidation-Reduction; Protein Binding; Protein Conformation; Pseudomonas; Spectrophotometry; Sulfites; Tryptophan; Tryptophan Oxygenase | 1971 |
Heterotropic co-operative effects between amino acid substrates of phenylalanine hydroxylase.
Topics: Binding Sites; Carbon Isotopes; Fluorine; Kinetics; Mixed Function Oxygenases; Models, Chemical; Phenylalanine; Phenylalanine Hydroxylase; Tryptophan | 1971 |
Inhibition of serotonin biosynthesis by 6-halotryptophans in vivo.
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carbon Radioisotopes; Carboxy-Lyases; Catechol O-Methyltransferase; Catecholamines; Catechols; Dopamine; Female; Fluorine; Hydroxyindoleacetic Acid; Ileum; In Vitro Techniques; Intestinal Mucosa; Kidney; Lung; Male; Metabolism; Methyltransferases; Mixed Function Oxygenases; Monoamine Oxidase; Myocardium; Norepinephrine; Pargyline; Rats; Serotonin; Spleen; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 1971 |
The subunit structure of jack-bean urease.
Topics: Amino Acid Sequence; Carboxypeptidases; Detergents; Electrophoresis; Fluorine; Hydrazines; Methionine; Molecular Weight; Nitrobenzenes; Plants; Pyrrolidinones; Sulfuric Acids; Thiocyanates; Trypsin; Tryptophan; Urease | 1969 |
Studies on human somatotropin. Preparation and some physico-chemical properties.
Topics: Amino Acid Sequence; Amino Acids; Ammonium Sulfate; Animals; Biological Assay; Body Weight; Carboxypeptidases; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Gel; Chromatography, Paper; Disulfides; Electrophoresis; Electrophoresis, Disc; Female; Fluorine; Formates; Freeze Drying; Growth Hormone; Humans; Hydrogen-Ion Concentration; Hypophysectomy; Isoflurophate; Macromolecular Substances; Molecular Weight; Nitrobenzenes; Oxidation-Reduction; Polarography; Polymers; Rats; Spectrophotometry; Tryptophan; Tyrosine; Ultraviolet Rays; Urea | 1969 |
Near-ultraviolet absorption bands of tryptophan. Studies using indole and 3-methylindole as models.
Topics: Chemical Phenomena; Chemistry; Cyclohexanes; Fluorescence; Fluorine; Hydrocarbons, Halogenated; Indoles; Models, Chemical; Solvents; Spectrophotometry; Tryptophan; Ultraviolet Rays | 1970 |
Biosynthesis of pyrrolnitrins by analogue-resistant mutants of Pseudomonas fluorescens.
Topics: Antifungal Agents; Biological Assay; Carbon Isotopes; Chemical Phenomena; Chemistry; Culture Media; Drug Resistance, Microbial; Fermentation; Fluorine; Genetics, Microbial; Mutation; Neurospora; Nitrophenols; Pseudomonas; Pyrroles; Stereoisomerism; Tryptophan | 1971 |
Preparation of substituted phenyl pyrroles through the metabolism of tryptophan analogues.
Topics: Antifungal Agents; Biological Assay; Fermentation; Fluorine; Magnetic Resonance Spectroscopy; Pseudomonas; Pyrroles; Spectrum Analysis; Tryptophan | 1968 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine | 1968 |
Phenylalanine hydroxylase activity towards two substrates simultaneously: enhancement of inhibition by phenylalanine, tryptophan and their derivatives.
Topics: Animals; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Fluorine; Fluorometry; Kinetics; Liver; Mixed Function Oxygenases; Phenylalanine; Pteridines; Rats; Tryptophan | 1968 |
[On the glycyl-glycine dipeptidase (EC 3.4.3.1) from porcine erythrocytes].
Topics: Animals; Benzene Derivatives; Cadmium; Caproates; Chloromercuribenzoates; Chromatography, Gel; Chromatography, Ion Exchange; Cobalt; Dipeptidases; Enzyme Activation; Erythrocytes; Fluorine; Histidine; Imidazoles; Indoleacetic Acids; Indoles; Leucine; Manganese; Mercury; Silver; Sulfones; Swine; Tryptophan; Zinc | 1968 |
Fluorine-19 nuclear magnetic resonance study of 5-fluorotryptophan-labeled histidine-binding protein J of Salmonella typhimurium.
Topics: Carrier Proteins; Fluorine; Histidine; Magnetic Resonance Spectroscopy; Mathematics; Periplasmic Binding Proteins; Protein Conformation; Salmonella typhimurium; Spectrometry, Fluorescence; Temperature; Tryptophan | 1984 |
Stopped-flow NMR spectroscopy: real-time unfolding studies of 6-19F-tryptophan-labeled Escherichia coli dihydrofolate reductase.
Topics: Circular Dichroism; Escherichia coli; Fluorine; Kinetics; Magnetic Resonance Spectroscopy; Protein Conformation; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tetrahydrofolate Dehydrogenase; Tryptophan | 1995 |
Fluorine-19 nuclear magnetic resonance spectroscopic study of fluorophenylalanine- and fluorotryptophan-labeled avian egg white lysozymes.
Topics: Amino Acid Sequence; Animals; Chickens; Female; Fluorine; Guanidine; Guanidines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Muramidase; Mutagenesis, Site-Directed; p-Fluorophenylalanine; Phenylalanine; Protein Conformation; Protein Denaturation; Quail; Recombinant Proteins; Tryptophan | 1994 |
A 19F-NMR study of the membrane-binding region of D-lactate dehydrogenase of Escherichia coli.
Topics: DNA Mutational Analysis; Escherichia coli; Fluorine; Kinetics; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Magnetic Resonance Spectroscopy; Membranes, Artificial; Mutagenesis, Site-Directed; Spin Labels; Tryptophan; Tyrosine | 1993 |
19F NMR relaxation studies on 5-fluorotryptophan- and tetradeutero-5-fluorotryptophan-labeled E. coli glucose/galactose receptor.
Topics: Anisotropy; Deuterium; Escherichia coli; Fluorine; Magnetic Resonance Spectroscopy; Receptors, Cell Surface; Tryptophan | 1996 |
A 19F-NMR study of the equilibrium unfolding of membrane-associated D-lactate dehydrogenase of Escherichia coli.
Topics: Circular Dichroism; Detergents; Escherichia coli; Fluorine; Guanidine; Guanidines; L-Lactate Dehydrogenase; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Membranes; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Solvents; Spectrometry, Fluorescence; Tryptophan | 1996 |
Real-time refolding studies of 6-19F-tryptophan labeled Escherichia coli dihydrofolate reductase using stopped-flow NMR spectroscopy.
Topics: Circular Dichroism; Escherichia coli; Fluorine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrophotometry; Tetrahydrofolate Dehydrogenase; Tryptophan | 1996 |
Effects of fluorine substitution on the structure and dynamics of complexes of dihydrofolate reductase (Escherichia coli).
Topics: Amides; Amino Acid Sequence; Binding Sites; Computer Simulation; Escherichia coli; Fluorine; Folic Acid; Ligands; Magnetic Resonance Spectroscopy; Methotrexate; Models, Chemical; Models, Structural; Protein Binding; Protein Conformation; Protein Structure, Secondary; Software; Tetrahydrofolate Dehydrogenase; Time Factors; Tryptophan | 1997 |
Refolding of [6-19F]tryptophan-labeled Escherichia coli dihydrofolate reductase in the presence of ligand: a stopped-flow NMR spectroscopy study.
Topics: Circular Dichroism; Escherichia coli; Fluorine; Folic Acid; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; NADP; Protein Folding; Spectrometry, Fluorescence; Tetrahydrofolate Dehydrogenase; Tryptophan | 1998 |
Incorporation of tryptophan analogues into staphylococcal nuclease, its V66W mutant, and Delta 137-149 fragment: spectroscopic studies.
Topics: Amino Acid Substitution; Circular Dichroism; Fluorine; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Mutagenesis, Site-Directed; Peptide Fragments; Spectrometry, Fluorescence; Tryptophan; Valine | 1998 |
Noncontact dipole effects on channel permeation. I. Experiments with (5F-indole)Trp13 gramicidin A channels.
Topics: Biophysical Phenomena; Biophysics; Electric Conductivity; Fluorine; Glycerides; Gramicidin; In Vitro Techniques; Indoles; Ion Channels; Kinetics; Lipid Bilayers; Membrane Potentials; Models, Chemical; Molecular Conformation; Onium Compounds; Permeability; Thermodynamics; Tryptophan | 1998 |
The role of beta-Arg-182, an essential catalytic site residue in Escherichia coli F1-ATPase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Amino Acid Substitution; Arginine; Binding Sites; Catalysis; Escherichia coli; Fluorine; Glutamine; Lysine; Mutagenesis, Site-Directed; Proton-Translocating ATPases; Spectrometry, Fluorescence; Tryptophan | 1999 |
Importance of F1-ATPase residue alpha-Arg-376 for catalytic transition state stabilization.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Arginine; Binding Sites; Catalysis; Cysteine; Enzyme Stability; Escherichia coli; Fluorine; Glutamine; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Proton-Translocating ATPases; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1999 |
Probing local environments of tryptophan residues in proteins: comparison of 19F nuclear magnetic resonance results with the intrinsic fluorescence of soluble human tissue factor.
Topics: Circular Dichroism; Crystallography, X-Ray; Fluorine; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Solvents; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thromboplastin; Tryptophan | 1999 |
Conformational changes in the human estrogen receptor observed by (19)F NMR.
Topics: Binding Sites; Estradiol; Fluorine; Glutathione Transferase; Humans; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Receptors, Estrogen; Recombinant Fusion Proteins; Tryptophan | 2000 |
19F NMR investigation of F(1)-ATPase of Escherichia coli using fluorotryptophan labeling.
Topics: 4-Chloro-7-nitrobenzofurazan; Carboxypeptidases; Dimethylamines; Escherichia coli; Fluorine; Glycine; Glyphosate; Magnetic Resonance Spectroscopy; Proton-Translocating ATPases; Tryptophan | 2000 |
Noncontact dipole effects on channel permeation. V. Computed potentials for fluorinated gramicidin.
Topics: Binding Sites; Cell Membrane Permeability; Fluorine; Gramicidin; Hydrogen Bonding; Ion Channels; Membrane Potentials; Protein Conformation; Rotation; Static Electricity; Thermodynamics; Tryptophan; Water | 2001 |
Real-time and equilibrium (19)F-NMR studies reveal the role of domain-domain interactions in the folding of the chaperone PapD.
Topics: Bacterial Proteins; Biophysical Phenomena; Biophysics; Circular Dichroism; Escherichia coli; Escherichia coli Proteins; Fluorine; Humans; Magnetic Resonance Spectroscopy; Molecular Chaperones; Mutagenesis, Site-Directed; Periplasmic Proteins; Protein Folding; Protein Structure, Tertiary; Tryptophan; Urea | 2002 |
Placement of 19F into the center of GB1: effects on structure and stability.
Topics: Bacterial Proteins; Circular Dichroism; Fluorine; Hemodynamics; Immunoglobulin G; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis; Mutation; Protein Conformation; Protein Denaturation; Protein Structure, Tertiary; Streptococcus; Thermodynamics; Tryptophan | 2002 |
Role of entropy in protein thermostability: folding kinetics of a hyperthermophilic cold shock protein at high temperatures using 19F NMR.
Topics: Bacterial Proteins; Calorimetry, Differential Scanning; Carrier Proteins; Entropy; Fluorine; Guanidine; Heat-Shock Proteins; Hot Temperature; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Spectrophotometry; Thermotoga maritima; Tryptophan | 2002 |
Noncontact dipole effects on channel permeation. VI. 5F- and 6F-Trp gramicidin channel currents.
Topics: Algorithms; Biophysical Phenomena; Biophysics; Cell Membrane Permeability; Computer Simulation; Electric Conductivity; Fluorine; Gramicidin; Ion Channels; Ion Transport; Kinetics; Lipid Bilayers; Membrane Potentials; Models, Chemical; Potassium; Sodium; Static Electricity; Tryptophan | 2002 |
Use of selective Trp side chain labeling to characterize protein-protein and protein-ligand interactions by NMR spectroscopy.
Topics: Carbon Isotopes; Escherichia coli; Fluorine; Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; Proteins; Recombinant Proteins; Tryptophan; X-Linked Inhibitor of Apoptosis Protein | 2003 |
Selective incorporation of 19F-labeled Trp side chains for NMR-spectroscopy-based ligand-protein interaction studies.
Topics: Escherichia coli; Escherichia coli Proteins; Fluorine; Hydrocarbons, Fluorinated; Indoles; Ligands; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Recombinant Proteins; Tryptophan | 2003 |
(19)F NMR studies of the leucine-isoleucine-valine binding protein: evidence that a closed conformation exists in solution.
Topics: Bacterial Proteins; Carrier Proteins; Escherichia coli Proteins; Fluorine; Mathematics; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Protein Denaturation; Solutions; Tryptophan | 2003 |
REQUIREMENT FOR P-FLUOROPHENYLALANINE ACTIVATION IN CONTROL OF RIBONUCLEIC ACID SYNTHESIS.
Topics: Carbon Isotopes; Escherichia coli; Feedback; Fluorides; Fluorine; Ligases; Metabolism; Mutation; p-Fluorophenylalanine; Pharmacology; Phenylalanine; Radiometry; Research; RNA; RNA, Bacterial; Shikimic Acid; Tryptophan; Tyrosine | 1965 |
Urea-dependent unfolding of murine adenosine deaminase: sequential destabilization as measured by 19F NMR.
Topics: Adenosine Deaminase; Animals; Circular Dichroism; Enzyme Stability; Fluorine; Magnetic Resonance Spectroscopy; Mice; Mutagenesis, Site-Directed; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tryptophan; Urea | 2004 |
19F NMR studies of plasminogen activator inhibitor-1.
Topics: Fluorine; Humans; Hydrolysis; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Plasminogen Activator Inhibitor 1; Recombinant Proteins; Serine Proteinase Inhibitors; Structure-Activity Relationship; Tissue Plasminogen Activator; Tryptophan | 2004 |
Quantitation of protein expression in a cell-free system: Efficient detection of yields and 19F NMR to identify folded protein.
Topics: Fluorine; Humans; Magnetic Resonance Spectroscopy; Proteins; Retinol-Binding Proteins; Tryptophan | 2005 |
Interaction of the eukaryotic pore-forming cytolysin equinatoxin II with model membranes: 19F NMR studies.
Topics: Animals; Cattle; Cell Membrane; Cnidarian Venoms; Cytotoxins; Fluorine; Hemolysis; Micelles; Models, Molecular; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Tertiary; Sea Anemones; Sphingomyelins; Tryptophan; Vasoconstrictor Agents | 2005 |
Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies.
Topics: Amides; Amino Acid Substitution; Base Sequence; Escherichia coli; Fluorine; Humans; Isotopes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutation; Myocardium; Nitrogen; Phenylalanine; Protein Conformation; Protein Folding; Protons; Recombinant Proteins; Solutions; Troponin C; Tryptophan | 2005 |
A residual structure in unfolded intestinal fatty acid binding protein consists of amino acids that are neighbors in the native state.
Topics: Amino Acids; Circular Dichroism; Fatty Acid-Binding Proteins; Fluorescence; Fluorine; Hydrophobic and Hydrophilic Interactions; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Tryptophan; Tyrosine; Urea | 2006 |
Alpha-synuclein structures probed by 5-fluorotryptophan fluorescence and 19F NMR spectroscopy.
Topics: alpha-Synuclein; Fluorescence; Fluorine; Isotopes; Magnetic Resonance Spectroscopy; Tryptophan | 2006 |
Tryptophan solvent exposure in folded and unfolded states of an SH3 domain by 19F and 1H NMR.
Topics: Fluorine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protons; Solvents; Thermodynamics; Tryptophan | 2006 |
Comparison of C40/82A and P27A C40/82A barstar mutants using 19F NMR.
Topics: Bacterial Proteins; Dose-Response Relationship, Drug; Fluorine; Hydrophobic and Hydrophilic Interactions; Motion; Mutation; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Temperature; Tryptophan; Ultracentrifugation; Urea | 2007 |
Side-chain conformation of the M2 transmembrane peptide proton channel of influenza a virus from 19F solid-state NMR.
Topics: Fluorine; Hydrogen-Ion Concentration; Influenza A virus; Ion Channels; Magnetic Resonance Spectroscopy; Peptides; Protein Conformation; Protons; Tryptophan; Viral Matrix Proteins | 2007 |
Long-range 19F-15N distance measurements in highly-13C, 15N-enriched solid proteins with 19F-dephased REDOR shift (FRESH) spectroscopy.
Topics: Carbon Isotopes; Fluorine; Isotope Labeling; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Proteins; Tryptophan | 2007 |
Solid-state 19F NMR spectroscopy reveals that Trp41 participates in the gating mechanism of the M2 proton channel of influenza A virus.
Topics: Fluorine; Histidine; Humans; Hydrogen-Ion Concentration; Ion Transport; Isotopes; Membrane Proteins; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Structure, Secondary; Protein Structure, Tertiary; Protons; Tryptophan; Viral Matrix Proteins | 2008 |
5-fluorotryptophan as dual probe for ground-state heterogeneity and excited-state dynamics in apoflavodoxin.
Topics: Apoproteins; Azotobacter vinelandii; Flavodoxin; Fluorescence Polarization; Fluorine; Magnetic Resonance Spectroscopy; Nuclear Magnetic Resonance, Biomolecular; Tryptophan | 2009 |
Calculation of fluorine chemical shift tensors for the interpretation of oriented (19)F-NMR spectra of gramicidin A in membranes.
Topics: Cell Membrane; Fluorine; Gramicidin; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Quantum Theory; Time Factors; Tryptophan | 2009 |
Asymmetric Mannich reaction of fluorinated ketoesters with a tryptophan-derived bifunctional thiourea catalyst.
Topics: Catalysis; Esters; Fluorine; Ketones; Molecular Conformation; Molecular Structure; Thiourea; Tryptophan | 2009 |
Rapid acquisition of 1H and 19F NMR experiments for direct and competition ligand-based screening.
Topics: Binding, Competitive; Fluorine; Humans; Ligands; Magnetic Resonance Spectroscopy; Protons; Serum Albumin; Solubility; Tryptophan | 2011 |
Simple and inexpensive incorporation of 19F-tryptophan for protein NMR spectroscopy.
Topics: Escherichia coli; Fluorine; Indoles; Nuclear Magnetic Resonance, Biomolecular; Proteins; Tryptophan | 2012 |
19F NMR as a probe of ligand interactions with the iNOS binding site of SPRY domain-containing SOCS box protein 2.
Topics: Binding Sites; Carrier Proteins; Fluorine; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Nitric Oxide Synthase Type II; Peptides; Protein Conformation; Surface Plasmon Resonance; Tryptophan | 2014 |
Atomic basis for therapeutic activation of neuronal potassium channels.
Topics: Animals; Anticonvulsants; Carbamates; Fluorine; Humans; Hydrogen Bonding; KCNQ Potassium Channels; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Molecular Docking Simulation; Mutagenesis, Site-Directed; Neurons; Oocytes; Patch-Clamp Techniques; Phenylenediamines; Tryptophan; Xenopus laevis | 2015 |
An artificial self-sufficient cytochrome P450 directly nitrates fluorinated tryptophan analogs with a different regio-selectivity.
Topics: Binding Sites; Biocatalysis; Cytochrome P-450 Enzyme System; Fluorine; Indoles; Nitrates; Protein Domains; Protein Engineering; Recombinant Fusion Proteins; Tandem Mass Spectrometry; Tryptophan | 2016 |
Topics: Density Functional Theory; Fluorine; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Tryptophan | 2018 |
Identification of biosynthetic genes for the β-carboline alkaloid kitasetaline and production of the fluorinated derivatives by heterologous expression.
Topics: Acetylcysteine; Alkaloids; Amidohydrolases; Carbolines; Cell Line, Tumor; Fluorine; Humans; Multigene Family; Mutation; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Streptomyces; Tryptophan | 2019 |
Topics: Cyclophilins; Fluorine; Indoles; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Tryptophan | 2019 |
Ex Vivo Analysis of Tryptophan Metabolism Using
Topics: Animals; Female; Fluorine; Gastrointestinal Microbiome; Magnetic Resonance Spectroscopy; Male; Proof of Concept Study; Rats, Sprague-Dawley; Tryptophan | 2019 |
What does fluorine do to a protein? Thermodynamic, and highly-resolved structural insights into fluorine-labelled variants of the cold shock protein.
Topics: Bacillus subtilis; Bacterial Proteins; Crystallography, X-Ray; Fluorine; Halogenation; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Conformation; Protein Stability; Thermodynamics; Tryptophan | 2020 |
Synthesis and Preclinical Evaluation of 6-[
Topics: Animals; Fluorine; Kynurenine; Mice; Positron-Emission Tomography; Radiopharmaceuticals; Tryptophan | 2020 |
Soluble Methane Monooxygenase Component Interactions Monitored by
Topics: Bacterial Proteins; Fluorine; Kinetics; Methylosinus trichosporium; Nuclear Magnetic Resonance, Biomolecular; Oxygenases; Protein Binding; Protein Structure, Quaternary; Protein Subunits; Tryptophan | 2021 |
Site-Specific Incorporation of 7-Fluoro-L-tryptophan into Proteins by Genetic Encoding to Monitor Ligand Binding by
Topics: Fluorine; Humans; Hydrogen; Ligands; Magnetic Resonance Spectroscopy; Proteins; Tryptophan; Zika Virus; Zika Virus Infection | 2022 |
Assessing the applicability of
Topics: Fluorine; Fluorine Radioisotopes; Nuclear Magnetic Resonance, Biomolecular; Proteins; Protons; Tryptophan | 2023 |