Compounds > tryptophan

tryptophan and etomidate

tryptophan has been researched along with etomidate in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bell, SV; Derry, JM; Garcia, PS; Jenkins, A; O'Toole, KK; Richardson, JE1
Cheng, Q; Desai, R; Forman, SA; Liu, A; Stewart, D1
Harris, RA; Howard, RJ; Johnson, WD; Trudell, JR1
Forman, SA; Hotta, M; Nourmahnad, A; Stern, AT; Stewart, DS; Szabo, A; Ziemba, AM1

Other Studies

5 other study(ies) available for tryptophan and etomidate

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A conserved tyrosine in the beta2 subunit M4 segment is a determinant of gamma-aminobutyric acid type A receptor sensitivity to propofol.
    Anesthesiology, 2007, Volume: 107, Issue:3

    Topics: Amino Acid Sequence; Anesthetics, General; Anesthetics, Intravenous; Cells, Cultured; Etomidate; Humans; Infusion Pumps; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Pregnenolone; Propofol; Receptors, GABA-A; Transfection; Tryptophan; Tyrosine

2007
Tryptophan mutations at azi-etomidate photo-incorporation sites on alpha1 or beta2 subunits enhance GABAA receptor gating and reduce etomidate modulation.
    Molecular pharmacology, 2008, Volume: 74, Issue:6

    Topics: Allosteric Regulation; Anesthetics, General; Animals; Binding Sites; Cell Line; Chloride Channels; Drug Synergism; Etomidate; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Ion Channel Gating; Mutation; Oocytes; Patch-Clamp Techniques; Photoaffinity Labels; Protein Structure, Tertiary; Protein Subunits; Receptors, GABA-A; Tryptophan; Xenopus laevis

2008
The TM2 6' position of GABA(A) receptors mediates alcohol inhibition.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2

    Topics: Alcohols; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Cysteine; Cystine; DNA, Complementary; Drug Synergism; Electrophysiological Phenomena; Ethanol; Etomidate; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Methionine; Methyl Methanesulfonate; Molecular Dynamics Simulation; Oocytes; Patch-Clamp Techniques; Receptors, GABA-A; Tryptophan; Xenopus laevis

2012
Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Intersubunit Sites for Four Intravenous Anesthetics and One Orphan Site.
    Anesthesiology, 2016, Volume: 125, Issue:6

    Topics: Amino Acid Substitution; Anesthetics, Intravenous; Animals; Barbiturates; Binding Sites; Cysteine; Etomidate; Female; Ion Channel Gating; Mutation; Pregnanediones; Propofol; Receptors, GABA-A; Tryptophan; Xenopus

2016