tryptophan and diazepam

tryptophan has been researched along with diazepam in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199022 (68.75)18.7374
1990's3 (9.38)18.2507
2000's2 (6.25)29.6817
2010's4 (12.50)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Bourgoin, S; Hanson, M; Héry, F; Ternaux, JP1
Agarwal, RA; Lapierre, YD; Rastogi, RB; Singhal, RL1
Lapierre, YD; Rastogi, RB; Singhal, RL1
Rastogi, RB; Singhal, RL1
Ball, HA; Davies, JA; Nicholson, AN1
Chadwick, D; Gorrod, JW; Jenner, P; Marsden, CD; Reynolds, EH1
Fenerty, CA; Lindup, WE2
Bhattacharya, SK; Clow, A; Glover, V; Halket, J; Przyborowska, A; Sandler, M1
Pouttu, J; Rosenberg, PH; Scheinin, M; Tuominen, M1
Cowen, PJ; Nutt, DJ2
Cowen, PJ; Franklin, M; Fraser, S; Gosden, B; Murdock, P; Nutt, DJ1
Hartmann, E1
Jus, A; Jus, K; Villeneuve, A1
Gautier, J; Jus, A; Jus, K; Pineau, R; Pires, P; Villeneuve, A; Villeneuve, R1
Gautier, J; Jus, A; Jus, K; Pineau, R; Pires, P; Villeneuv, R; Villeneuve, A1
Nuller, JL; Ostroumova, MN1
Kennedy, B; Leonard, BE1
Vellucci, SV; Webster, RA1
Kragh-Hansen, U2
Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK1
Goodwin, FK; Hirata, F; Marangos, PJ; Patel, J; Paul, SM; Skolnick, P; Sondhein, D1
Coull, JT; Cowen, PJ; McShane, RH; Middleton, HC; Park, SB; Robbins, TW; Sahakian, BJ; Young, AH1
Mushahid Khan, M; Sharma, N; Tayyab, S1
Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA1
Kitade, T; Kitamura, K; Niinobu, M; Omran, AA; Takegami, S1
Anraku, M; Chuang, VT; Ishima, Y; Jinnouchi, H; Kadowaki, D; Kubota, K; Maruyama, T; Matsushita, K; Nagumo, K; Otagiri, M; Sasaki, Y; Setoyama, H; Tanaka, M; Watanabe, H; Yamada, N; Yoshida, A1
Appolonova, SA; Brito, A; La Frano, MR; Markin, PA; Moskaleva, NE; Savitskii, MV; Tagliaro, F; Tarasov, VV1

Reviews

2 review(s) available for tryptophan and diazepam

ArticleYear
Brain 5-hydroxytryptamine metabolism: adaptive changes after long-term administration of psychotropic drugs.
    General pharmacology, 1978, Volume: 9, Issue:5

    Topics: Adrenal Cortex Hormones; Animals; Brain; Cocaine; Diazepam; Hyperthyroidism; Hypothyroidism; Lithium; Morphine; Psychotropic Drugs; Rats; Receptors, Serotonin; Serotonin; Tryptophan; Tryptophan Hydroxylase

1978
Pharmacological studies of sleep and dreaming: chemical and clinical relationships.
    Biological psychiatry, 1969, Volume: 1, Issue:3

    Topics: Amitriptyline; Amphetamine; Antidepressive Agents; Atropine; Chloralose; Chlordiazepoxide; Chlorpromazine; Desipramine; Dextroamphetamine; Diazepam; Diphenhydramine; Dreams; Glutethimide; Humans; Hypnotics and Sedatives; Imipramine; Lysergic Acid Diethylamide; Meprobamate; Methaqualone; Morphine; Nialamide; Pentobarbital; Reserpine; Sleep; Sleep, REM; Tranquilizing Agents; Tranylcypromine; Triiodothyronine; Tryptophan

1969

Trials

2 trial(s) available for tryptophan and diazepam

ArticleYear
Effects of oral clonidine premedication on concentrations of cortisol and monoamine neurotransmitters and their metabolites in cerebrospinal fluid and plasma.
    Acta anaesthesiologica Scandinavica, 1989, Volume: 33, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Adult; Anesthesia, Spinal; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method; Epinephrine; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Preanesthetic Medication; Random Allocation; Tryptophan

1989
Differential effects of clonidine, haloperidol, diazepam and tryptophan depletion on focused attention and attentional search.
    Psychopharmacology, 1995, Volume: 121, Issue:2

    Topics: Adult; Attention; Clonidine; Diazepam; Haloperidol; Humans; Placebo Effect; Reaction Time; Tryptophan

1995

Other Studies

28 other study(ies) available for tryptophan and diazepam

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Effects of benzodiazepines on the binding of tryptophan in serum. Consequences on 5-hydroxyindoles concentrations in the rat brain.
    Psychopharmacology communications, 1975, Volume: 1, Issue:2

    Topics: Amino Acids; Animals; Anti-Anxiety Agents; Brain Chemistry; Chlordiazepoxide; Diazepam; Hydroxyindoleacetic Acid; In Vitro Techniques; Indoles; Male; Oxazepam; Protein Binding; Rats; Serum Albumin; Time Factors; Tryptophan; Tyrosine

1975
Alterations in brain 5-hydroxytryptamine metabolism during the 'withdrawal' phase after chronic treatment with diazepam and bromazepam.
    British journal of pharmacology, 1977, Volume: 60, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Brain; Bromazepam; Diazepam; Humans; Hydroxyindoleacetic Acid; Male; Mesencephalon; Monoamine Oxidase; Rats; Serotonin; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Hydroxylase

1977
Synaptosomal uptake of norepinephrine and 5-hydroxytryptamine and synthesis of catecholamines during benzodiazepine treatment.
    Canadian journal of physiology and pharmacology, 1978, Volume: 56, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Brain; Catecholamines; Diazepam; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Motor Activity; Norepinephrine; Rats; Serotonin; Synaptosomes; Time Factors; Tryptophan

1978
Effect of diazepam and its metabolites on the binding of L-tryptophan to human serum albumen [proceedings].
    British journal of pharmacology, 1979, Volume: 66, Issue:1

    Topics: Binding, Competitive; Diazepam; Humans; Protein Binding; Serum Albumin; Tryptophan

1979
Functional changes in cerebral 5-hydroxytryptamine metabolism in the mouse induced by anticonvulsant drugs.
    British journal of pharmacology, 1978, Volume: 62, Issue:1

    Topics: Animals; Behavior, Animal; Benzodiazepinones; Brain; Clonazepam; Cytochrome P-450 Enzyme System; Diazepam; Hydroxyindoleacetic Acid; Liver; Male; Mice; Phenytoin; Serotonin; Sleep; Time Factors; Tryptophan

1978
Effect of beta-carboline derivatives on the binding of L-tryptophan and diazepam to bovine and human albumin.
    Biochemical pharmacology, 1991, Jun-01, Volume: 41, Issue:11

    Topics: Albumins; Animals; Binding Sites; Carbolines; Cattle; Diazepam; Humans; Indoles; Kinetics; Protein Binding; Receptors, GABA-A; Tryptophan

1991
Effect of aromatic amino acids, pentylenetetrazole and yohimbine on isatin and tribulin activity in rat brain.
    Neuroscience letters, 1991, Oct-28, Volume: 132, Issue:1

    Topics: Animals; Brain; Diazepam; Isatin; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Yohimbine

1991
Brain uptake of L-tryptophan and diazepam: the role of plasma protein binding.
    Journal of neurochemistry, 1989, Volume: 53, Issue:2

    Topics: Animals; Blood Proteins; Brain; Diazepam; Inulin; Male; Osmotic Pressure; Rats; Rats, Inbred Strains; Tryptophan; Viscosity

1989
Benzodiazepine-serotonin interactions in man.
    Psychopharmacology series, 1987, Volume: 3

    Topics: Adult; Brain; Diazepam; Growth Hormone; Humans; Male; Prolactin; Serotonin; Synaptic Transmission; Tryptophan; Wakefulness

1987
The effect of diazepam on indices of 5-HT function in man.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:5

    Topics: Adult; Blood Platelets; Diazepam; Humans; Hypnotics and Sedatives; Imipramine; Male; Nordazepam; Prolactin; Serotonin; Time Factors; Tryptophan

1986
Diazepam alters brain 5-HT function in man: implications for the acute and chronic effects of benzodiazepines.
    Psychological medicine, 1987, Volume: 17, Issue:3

    Topics: Adult; Brain Chemistry; Diazepam; Growth Hormone; Humans; Male; Neurosecretory Systems; Prolactin; Serotonin; Tryptophan

1987
Polygraphic profile of oral tardive dyskinesia and of rabbit syndrome: for quantitative and qualitative evaluation.
    Diseases of the nervous system, 1973, Volume: 34, Issue:1

    Topics: Attention; Basal Ganglia Diseases; Benztropine; Diazepam; Electroencephalography; Electromyography; Humans; Lip; Masticatory Muscles; Motor Skills; Movement Disorders; Phenytoin; Sleep; Sleep, REM; Tremor; Tryptophan; Wakefulness

1973
[Study of the effect of certain pharmacological agents on tardive dyskinesias and the rabbit syndrome].
    La Vie medicale au Canada francais, 1973, Volume: 2, Issue:9

    Topics: Antiparkinson Agents; Benztropine; Diazepam; Humans; Movement Disorders; Tranquilizing Agents; Tropanes; Tryptophan

1973
Studies on the action of certain pharmacological agents on tardive dyskinesia and on the rabbit syndrome.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 9, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antiparkinson Agents; Benztropine; Diazepam; Female; Humans; Injections, Intravenous; Male; Middle Aged; Movement Disorders; Phenytoin; Tranquilizing Agents; Tryptophan

1974
Resistance to inhibiting effect of dexamethasone in patients with endogenous depression.
    Acta psychiatrica Scandinavica, 1980, Volume: 61, Issue:2

    Topics: 11-Hydroxycorticosteroids; Adolescent; Adult; Aged; Anti-Anxiety Agents; Corticotropin-Releasing Hormone; Depression; Dexamethasone; Diazepam; Drug Synergism; Female; Humans; Levodopa; Male; Middle Aged; Serotonin; Tryptophan

1980
Similarity between the action of nicotinamide and diazepam on neurotransmitter metabolism in the rat [proceedings].
    Biochemical Society transactions, 1980, Volume: 8, Issue:1

    Topics: Alkynes; Aminocaproates; Amygdala; Animals; Brain; Diazepam; gamma-Aminobutyric Acid; Hippocampus; Hydroxyindoleacetic Acid; Male; Niacinamide; Organ Specificity; Rats; Serotonin; Tryptophan

1980
Modification of diazepam's antileptazol activity by endogenous tryptophan-like compounds.
    European journal of pharmacology, 1981, Dec-03, Volume: 76, Issue:2-3

    Topics: Adrenocorticotropic Hormone; Animals; Carbolines; Diazepam; Dipeptides; Female; Ligands; Mice; Pentylenetetrazole; Receptors, Drug; Receptors, GABA-A; Tryptophan

1981
Graphical analysis of competitive binding of comparable concentrations of ligand, inhibitor and protein. Ligand binding to serum albumin.
    Biochemical pharmacology, 1983, Sep-15, Volume: 32, Issue:18

    Topics: Binding Sites; Binding, Competitive; Diazepam; Humans; Kinetics; Ligands; Mathematics; Protein Binding; Serum Albumin; Tryptophan

1983
Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat.
    Acta physiologica Scandinavica, 1982, Volume: 115, Issue:1

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Cerebrovascular Circulation; Diazepam; Dihydroxyphenylalanine; Hypercapnia; Hypoxia; Male; Oxygen Consumption; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine

1982
Relations between high-affinity binding sites for L-tryptophan, diazepam, salicylate and Phenol Red on human serum albumin.
    The Biochemical journal, 1983, Jan-01, Volume: 209, Issue:1

    Topics: Binding Sites; Diazepam; Humans; Ligands; Models, Chemical; Phenolphthaleins; Phenolsulfonphthalein; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Tryptophan

1983
Inhibition of diazepam binding by tryptophan derivatives including melatonin and its brain metabolite N-acetyl-5-methoxy kynurenamine.
    Life sciences, 1981, Jul-20, Volume: 29, Issue:3

    Topics: Animals; Binding, Competitive; Brain; Diazepam; In Vitro Techniques; Inosine; Kinetics; Kynuramine; Melatonin; Propiophenones; Rats; Synaptosomes; Tryptophan

1981
Use of domain specific ligands to study urea-induced unfolding of bovine serum albumin.
    Biochemical and biophysical research communications, 2000, Oct-14, Volume: 277, Issue:1

    Topics: Animals; Bilirubin; Cattle; Chloroform; Diazepam; Dose-Response Relationship, Drug; Fluorescence; Ligands; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence; Tryptophan; Urea

2000
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
    The Journal of endocrinology, 2000, Volume: 167, Issue:3

    Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil

2000
Binding of diuretic antihypertensive bendroflumethiazide to human serum albumin studied by ¹⁹F nuclear magnetic resonance method.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Jan-23, Volume: 45, Issue:1-2

    Topics: Antihypertensive Agents; Bendroflumethiazide; Binding Sites; Binding, Competitive; Diazepam; Diuretics; Humans; Iopanoic Acid; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Osmolar Concentration; Phenylbutazone; Protein Binding; Serum Albumin; Serum Albumin, Human; Tryptophan

2012
Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic diseases.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Aged; Amino Acids, Branched-Chain; Bilirubin; Biomarkers; Chronic Disease; Cysteine; Diabetes Mellitus; Diazepam; Female; Glycation End Products, Advanced; Humans; Liver Cirrhosis; Male; Middle Aged; Models, Molecular; Oxidation-Reduction; Oxidative Stress; Protein Binding; Renal Insufficiency; Serum Albumin; Spectrometry, Mass, Electrospray Ionization; Tryptophan; Warfarin

2014
Short- and medium-term exposures of diazepam induce metabolomic alterations associated with the serotonergic, dopaminergic, adrenergic and aspartic acid neurotransmitter systems in zebrafish (Danio rerio) embryos/larvae.
    Comparative biochemistry and physiology. Part D, Genomics & proteomics, 2021, Volume: 38

    Topics: Animals; Aspartic Acid; Diazepam; Embryo, Nonmammalian; Hypnotics and Sedatives; Larva; Metabolome; Neurotransmitter Agents; Serotonin; Tryptophan; Zebrafish

2021