tryptophan has been researched along with cocaine in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (38.46) | 18.7374 |
| 1990's | 9 (23.08) | 18.2507 |
| 2000's | 8 (20.51) | 29.6817 |
| 2010's | 3 (7.69) | 24.3611 |
| 2020's | 4 (10.26) | 2.80 |
| Authors | Studies |
|---|---|
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Rastogi, RB; Singhal, RL | 1 |
| Knapp, S; Mandell, AJ | 5 |
| Aleksidze, NG; Bakhanashvili, TA; Maĭsov, NI; Raevskiĭ, KS | 1 |
| Moore, KE; Wuerthele, SM | 1 |
| Friedman, E; Gershon, S; Rotrosen, J | 1 |
| Chadwick, MJ; Gregory, DL; Wendling, G | 1 |
| Asencio, M; Carroll, ME; Kragh, R; Lac, ST | 1 |
| Pike, RF | 1 |
| Berman, ML; Tennant, F | 1 |
| Lee, EH; Mandell, AJ | 1 |
| Afrikanov, II; Vedernikov, YP | 1 |
| Vedernikov, YP | 1 |
| Marley, E; Vane, JR | 1 |
| Aronson, SC; Black, JE; Heninger, GR; Jatlow, P; Kosten, TR; McDougle, CJ; Price, LH; Scanley, BE | 1 |
| Charney, DS; Delgado, PL; Kosten, TR; Krystal, JH; Satel, SL | 1 |
| Baker, G; McGregor, A; Roberts, DC | 1 |
| Lacosta, S; McGregor, A; Roberts, DC | 1 |
| Darmani, NA | 2 |
| Charney, DS | 1 |
| Lin, Z; Uhl, GR; Wang, W | 1 |
| Chen, N; Reith, ME; Vaughan, RA | 1 |
| Abumrad, NN; Ahmed, N; Gatley, J; Molina, PE; Volkow, ND | 1 |
| Brimijoin, S; Lockridge, O; Pang, YP; Sun, H | 1 |
| Carta, M; Collu, M; Fadda, F; Stancampiano, R | 1 |
| Hinttala, R; Kärppä, M; Majamaa, K; Remes, AM; Soini, H; Takalo, R; Uusimaa, J | 1 |
| Carrico, AW; Fuchs, D; Hecht, FM; Johnson, MO; Morin, SF; Remien, RH; Riley, ED | 1 |
| Chen, N; Dutta, AK; Kharkar, P; Mishra, M; Reith, ME; Schmitt, KC; Zhen, J | 1 |
| Benkelfat, C; Casey, KF; Cox, SM; Dagher, A; Delaney, JS; Durand, F; Kolivakis, T; Leyton, M | 1 |
| Ballestín, R; Colado, MI; Ferrer-Pérez, C; Gil de Biedma-Elduayen, L; Giménez-Gómez, P; Miñarro, J; O'Shea, E; Reguilón, MD; Rodríguez-Arias, M; Vidal, R | 1 |
| Greis, KD; Kirley, TL; Norman, AB | 1 |
| Dong, W; Hou, Z; Liu, H; Wang, H; Xie, J; Zeng, Z; Zhao, Z; Zhou, X | 1 |
| Araos, P; Castilla-Ortega, E; Flores-López, M; García-Marchena, N; Pavón-Morón, FJ; Pedraza, C; Requena-Ocaña, N; Rodríguez de Fonseca, F; Serrano, A; Wallace, A | 1 |
2 review(s) available for tryptophan and cocaine
| Article | Year |
|---|---|
Brain 5-hydroxytryptamine metabolism: adaptive changes after long-term administration of psychotropic drugs.
Topics: Adrenal Cortex Hormones; Animals; Brain; Cocaine; Diazepam; Hyperthyroidism; Hypothyroidism; Lithium; Morphine; Psychotropic Drugs; Rats; Receptors, Serotonin; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1978 |
Monoamine dysfunction and the pathophysiology and treatment of depression.
Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents; Carrier Proteins; Catecholamines; Cocaine; Depressive Disorder; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Morpholines; Nerve Tissue Proteins; Neuropeptides; Norepinephrine; Reboxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tomography, Emission-Computed, Single-Photon; Tryptophan | 1998 |
3 trial(s) available for tryptophan and cocaine
| Article | Year |
|---|---|
A double-blind amino acids, L-tryptophan and L-tyrosine, and placebo study with cocaine-dependent subjects in an inpatient chemical dependency treatment center.
Topics: Adolescent; Adult; Cocaine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; MMPI; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine | 1990 |
Serotonergic mechanisms of cocaine effects in humans.
Topics: Adult; Affect; Cocaine; Depression, Chemical; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Serotonin; Substance-Related Disorders; Time Factors; Tryptophan | 1995 |
Tryptophan depletion and attenuation of cue-induced craving for cocaine.
Topics: Adult; Amino Acids; Cocaine; Cues; Double-Blind Method; Drinking; Habituation, Psychophysiologic; Hospitalization; Humans; Male; Middle Aged; Placebos; Racial Groups; Recurrence; Serotonin; Substance Abuse, Intravenous; Substance-Related Disorders; Treatment Outcome; Tryptophan | 1995 |
34 other study(ies) available for tryptophan and cocaine
| Article | Year |
|---|---|
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Asymmetry and mood, emergent properties of serotonin regulation.
Topics: Affect; Amphetamine; Animals; Bipolar Disorder; Brain; Calcium; Cocaine; Dominance, Cerebral; Humans; Hydroxyindoleacetic Acid; Kinetics; Lithium; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1979 |
[Tryptophan uptake by glia and synaptosomes of rabbit cerebral cortex].
Topics: Animals; Cerebral Cortex; Chlorpromazine; Cocaine; Imipramine; Kinetics; Neuroglia; Rabbits; Synaptosomes; Trifluperidol; Tryptophan | 1978 |
Studies on the mechanisms of L-dopa-induced depletion of 5-hydroxytryptamine in the mouse brain.
Topics: Amines; Animals; Benztropine; Biological Transport; Brain; Clomipramine; Cocaine; Dihydroxyphenylalanine; Dopamine; Imipramine; Levodopa; Male; Mice; Mice, Inbred ICR; Serotonin; Tryptophan | 1977 |
A neurobiological model for the symmetrical prophylactic action of lithium in bipolar affective disorder.
Topics: Animals; Bipolar Disorder; Brain; Cocaine; Corpus Striatum; Humans; Kinetics; Lithium; Male; Mesencephalon; Models, Biological; Morphine; Rats; Serotonin; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1976 |
Effects of acute cocaine treatment on the turnover of 5-hydroxytryptamine in the rat brain.
Topics: Amphetamine; Animals; Behavior, Animal; Brain; Brain Chemistry; Cocaine; Depression, Chemical; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Monoamine Oxidase Inhibitors; Pargyline; Probenecid; Rats; Serotonin; Tryptophan | 1975 |
Current research in the indoleamine hypothesis of affective disorders.
Topics: Affective Symptoms; Animals; Bipolar Disorder; Brain; Cocaine; Humans; Indoles; Lithium; Male; Morphine; Rats; Serotonin; Synaptosomes; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1975 |
Cocaine and lithium: neurobiological antagonism in the serotonin biosynthetic system in rat brain.
Topics: Animals; Cocaine; Corpus Striatum; Lithium; Male; Mesencephalon; Rats; Serotonin; Synaptosomes; Tryptophan; Tryptophan Hydroxylase | 1976 |
Intravenous cocaine self-administration in rats is reduced by dietary L-tryptophan.
Topics: Animals; Cocaine; Diet; Male; Rats; Rats, Inbred Strains; Self Administration; Tryptophan | 1990 |
Cocaine withdrawal. An effective three-drug regimen.
Topics: Amantadine; Cocaine; Humans; Lorazepam; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan | 1989 |
Stepwise detoxification from cocaine. A promising regimen.
Topics: Adolescent; Adult; Amantadine; Bromocriptine; Cocaine; Desipramine; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine | 1988 |
Relationships between drug-induced changes in tetrahydrobiopterin and biogenic amine concentrations in rat brain.
Topics: Animals; Biogenic Amines; Biopterins; Brain Chemistry; Circadian Rhythm; Cocaine; Corticotropin-Releasing Hormone; Dextroamphetamine; Male; Methylphenidate; Pteridines; Rats; Rats, Inbred Strains; Tryptophan; Valine | 1985 |
On the role of a central adrenergic mechanism in morphine analgesic action.
Topics: Amphetamine; Animals; Brain; Cocaine; Disulfiram; Drug Synergism; Female; Iproniazid; Methyldopa; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan | 1969 |
The role of brain catecholamines in morphine analgesic action in morphine tolerant rats.
Topics: Amphetamine; Analgesics; Animals; Brain; Catecholamines; Cocaine; Disulfiram; Drug Synergism; Drug Tolerance; Female; Iproniazid; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan | 1970 |
Narcotic drugs: effects on the serotonin biosynthetic systems of the brain.
Topics: Animals; Brain; Carbon Isotopes; Cocaine; Male; Mesencephalon; Mixed Function Oxygenases; Morphine; Nerve Endings; Rats; Serotonin; Synaptic Vesicles; Synaptosomes; Time Factors; Tryptophan | 1972 |
Tryptamines and spinal cord reflexes in cats.
Topics: 5-Hydroxytryptophan; Amines; Animals; Blood Pressure; Cats; Cocaine; Drug Synergism; Female; Indoleacetic Acids; Male; Methysergide; Neuromuscular Junction; Norepinephrine; Phenoxybenzamine; Reflex; Reserpine; Serotonin; Spinal Cord; Tryptamines; Tryptophan; Tyramine | 1967 |
Effect of 6-hydroxydopamine lesions of the amygdala on intravenous cocaine self-administration under a progressive ratio schedule of reinforcement.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Amygdala; Analysis of Variance; Animals; Behavior, Animal; Benzazepines; Brain; Chlordiazepoxide; Cocaine; Desipramine; Dopamine; Estrus; Female; Fluoxetine; Ibotenic Acid; Injections, Intravenous; Male; Organ Specificity; Oxidopamine; Rats; Rats, Wistar; Self Administration; Time Factors; Tryptophan | 1994 |
L-tryptophan decreases the breaking point under a progressive ratio schedule of intravenous cocaine reinforcement in the rat.
Topics: Animals; Cocaine; Conditioning, Operant; Injections, Intravenous; Male; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration; Tryptophan | 1993 |
Differential potentiation of L-tryptophan-induced head-twitch response in mice by cocaine and sertraline.
Topics: 1-Naphthylamine; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Drug Synergism; Fluoxetine; Head Movements; Male; Mice; Mice, Inbred ICR; Norepinephrine; Piperazines; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Sertraline; Tryptophan | 1996 |
Withdrawal from chronic cocaine administration causes prolonged deficits in L-tryptophan-induced head-twitch response in mice.
Topics: Analysis of Variance; Animals; Cocaine; Drug Administration Schedule; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase Inhibitors; Motor Activity; Opioid-Related Disorders; Serotonin; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors; Tranylcypromine; Tryptophan | 1997 |
Dopamine transporter tryptophan mutants highlight candidate dopamine- and cocaine-selective domains.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Carrier Proteins; Cations; Cocaine; COS Cells; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Immunohistochemistry; Ions; Membrane Glycoproteins; Membrane Transport Proteins; Models, Biological; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Protein Conformation; Radioligand Assay; Signal Transduction; Tritium; Tryptophan | 2000 |
The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Aspartic Acid; Carrier Proteins; Cell Line; Cocaine; Conserved Sequence; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Kinetics; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Protein Structure, Secondary; Radioligand Assay; Recombinant Proteins; Transfection; Tritium; Tryptophan | 2001 |
L-tryptophan attenuation of the dopaminergic and behavioral responses to cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine; Hyperkinesis; Injections, Intraperitoneal; Injections, Intravenous; Male; Microdialysis; Narcotic Antagonists; Nucleus Accumbens; Random Allocation; Rats; Rats, Sprague-Dawley; Tryptophan | 2001 |
Re-engineering butyrylcholinesterase as a cocaine hydrolase.
Topics: Alanine; Amino Acid Substitution; Animals; Butyrylcholinesterase; CHO Cells; Cocaine; Cricetinae; Genetic Engineering; Hydrolases; Models, Molecular; Tryptophan; Tyrosine | 2002 |
Augmented cocaine-induced accumbal dopamine efflux, motor activity and place preference in rats fed with a tryptophan-deficient diet.
Topics: Animals; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Disease Models, Animal; Dopamine; Environment, Controlled; Exploratory Behavior; Extracellular Fluid; Food, Formulated; Hydroxyindoleacetic Acid; Hyperkinesis; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan | 2006 |
Parkinsonism associated with the homozygous W748S mutation in the POLG1 gene.
Topics: Aged; Cocaine; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Humans; Male; Mutation; Parkinsonian Disorders; Radiopharmaceuticals; Serine; Tomography, Emission-Computed, Single-Photon; Tryptophan | 2008 |
Stimulant use is associated with immune activation and depleted tryptophan among HIV-positive persons on anti-retroviral therapy.
Topics: Adult; Affective Symptoms; Anti-Retroviral Agents; CD4-Positive T-Lymphocytes; Cocaine; Female; HIV Infections; HIV Seropositivity; Humans; Male; Methamphetamine; Middle Aged; Neopterin; Patient Compliance; Reverse Transcriptase Polymerase Chain Reaction; Tryptophan; Viral Load | 2008 |
Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.
Topics: Animals; Asparagine; Aspartic Acid; Benztropine; Binding, Competitive; Cell Line, Transformed; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Leucine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Structure, Tertiary; Sodium; Structure-Activity Relationship; Transfection; Tritium; Tryptophan | 2008 |
Effects of lowered serotonin transmission on cocaine-induced striatal dopamine response: PET [¹¹C]raclopride study in humans.
Topics: Administration, Intranasal; Adult; Analysis of Variance; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Magnetic Resonance Imaging; Male; Positron-Emission Tomography; Raclopride; Radiopharmaceuticals; Serotonin; Tryptophan; Young Adult | 2011 |
Decreased kynurenine pathway potentiate resilience to social defeat effect on cocaine reward.
Topics: Animals; Cerebellum; Cocaine; Conditioning, Operant; Environment; Indomethacin; Kynurenine; Male; Mice; Mice, Inbred C57BL; Oxytocin; Resilience, Psychological; Reward; Signal Transduction; Social Defeat; Tryptophan | 2021 |
Oxidation of specific tryptophan residues inhibits high-affinity binding of cocaine and its metabolites to a humanized anticocaine mAb.
Topics: Antibodies, Monoclonal, Humanized; Cocaine; Immunoglobulin Fab Fragments; Oxidation-Reduction; Tryptophan | 2022 |
Advanced aromatic organic compounds removal from refractory coking wastewater in a step-feed three-stage integrated A/O bio-filter: Spectrum characterization and biodegradation mechanism.
Topics: Biodegradation, Environmental; Bioreactors; Coke; Humic Substances; Indoles; Organic Chemicals; Phenol; Pyridines; Quinolines; Sewage; Tryptophan; Waste Disposal, Fluid; Wastewater | 2022 |
Plasma Lysophosphatidic Acid Concentrations in Sex Differences and Psychiatric Comorbidity in Patients with Cocaine Use Disorder.
Topics: Child; Cocaine; Comorbidity; Cross-Sectional Studies; Female; Humans; Male; Sex Characteristics; Substance-Related Disorders; Tryptophan | 2023 |