tryptophan and aplysinopsin

tryptophan has been researched along with aplysinopsin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's9 (60.00)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Aoki, S; Higuchi, K; Kitagawa, I; Kobayashi, M; Takashima, A; Tanaka, Y; Ye, Y1
Chauhan, PM; Chauhan, SS; Gupta, S; Porwal, S; Shakya, N; Verma, A1
Crooks, PA; Penthala, NR; Yerramreddy, TR2
Crooks, PA; Damodaran, C; Koduru, S; Narsimha Reddy, P; Thirupathi Reddy, Y1
Canseco, DC; Cummings, DF; Johnson, JE; Schetz, JA; Sheth, P1
Ebada, SS; Proksch, P1
Bialonska, D; Chaurasiya, ND; Lewellyn, K; Tekwani, BL; Zjawiony, JK1
Bialonska, D; Lewellyn, K; Loria, MJ; Sufka, KJ; White, SW; Zjawiony, JK1
Beniddir, MA; Bernadat, G; Evanno, L; Joseph, D; Leblanc, K; Poupon, E; Skiredj, A1
de Voog, NJ; Li, GQ; Li, PL; Luo, XC; Tang, XL; Wang, Q1
Carpes, RM; Coelho, MGP; Corrêa Fernandes, D; Creed, JC; Felzenszwalb, I; Fleury, BG; Garden, SJ1
Cerella, C; Christov, C; Dicato, M; Diederich, M; El-Sawy, ER; Kim, S; Kirsch, G; Orlikova-Boyer, B; Song, S1
Ashraf, GM; G, VB; Ganash, M; Shen, B; Singla, RK1
El-Sawy, ER; Kirsch, G1

Reviews

2 review(s) available for tryptophan and aplysinopsin

ArticleYear
Chemical and pharmacological significance of natural guanidines from marine invertebrates.
    Mini reviews in medicinal chemistry, 2011, Volume: 11, Issue:3

    Topics: Animals; Aquatic Organisms; Guanidines; Invertebrates; Peptides; Pyrimidines; Pyrroles; Tryptophan; Tyrosine

2011
An Overview of Aplysinopsins: Synthesis and Biological Activities.
    Marine drugs, 2023, Apr-26, Volume: 21, Issue:5

    Topics: Alkaloids; Animals; Anthozoa; Antineoplastic Agents; Aquatic Organisms; Biological Products; Tryptophan

2023

Other Studies

13 other study(ies) available for tryptophan and aplysinopsin

ArticleYear
Novel neuronal nitric oxide synthase (nNOS) selective inhibitor, aplysinopsin-type indole alkaloid, from marine sponge Hyrtios erecta.
    Chemical & pharmaceutical bulletin, 2001, Volume: 49, Issue:10

    Topics: Animals; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Oxidation-Reduction; Porifera; Rats; Rats, Wistar; Spectrophotometry, Infrared; Tryptophan

2001
Discovery of novel antileishmanial agents in an attempt to synthesize pentamidine-aplysinopsin hybrid molecule.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: Animals; Antiprotozoal Agents; Cell Line; Drug Discovery; Indoles; Inhibitory Concentration 50; Leishmania donovani; Macrophages; Mice; Parasitic Sensitivity Tests; Pentamidine; Structure-Activity Relationship; Tryptophan

2009
Microwave assisted synthesis and in vitro cytotoxicities of substituted (Z)-2-amino-5-(1-benzyl-1H-indol-3-yl)methylene-1-methyl-1H-imidazol-4(5H)-ones against human tumor cell lines.
    Bioorganic & medicinal chemistry letters, 2010, Jan-15, Volume: 20, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Imidazoles; Indoles; Microwaves; Tryptophan

2010
Aplysinopsin analogs: Synthesis and anti-proliferative activity of substituted (Z)-5-(N-benzylindol-3-ylmethylene)imidazolidine-2,4-diones.
    Bioorganic & medicinal chemistry, 2010, May-15, Volume: 18, Issue:10

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Design; Drug Screening Assays, Antitumor; Humans; Imidazolidines; Indoles; Inhibitory Concentration 50; Structure-Activity Relationship; Tryptophan

2010
Synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-HT1A, 5-HT2A, 5-HT2C receptor subtypes.
    Bioorganic & medicinal chemistry, 2010, Jul-01, Volume: 18, Issue:13

    Topics: Animals; Binding, Competitive; Humans; Imidazolidines; Indoles; Porifera; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Structure-Activity Relationship; Tryptophan

2010
Synthesis and in vitro screening of novel N-benzyl aplysinopsin analogs as potential anticancer agents.
    Bioorganic & medicinal chemistry letters, 2011, Mar-01, Volume: 21, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Molecular Structure; Tryptophan

2011
Synthesis and evaluation of aplysinopsin analogs as inhibitors of human monoamine oxidase A and B.
    Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15

    Topics: Enzyme Activation; Enzyme Inhibitors; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Structure-Activity Relationship; Tryptophan

2012
In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model.
    Bioorganic & medicinal chemistry, 2013, Nov-15, Volume: 21, Issue:22

    Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Chickens; Depression; Disease Models, Animal; Humans; Monoamine Oxidase; Protein Binding; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Structure-Activity Relationship; Tryptophan

2013
A unified bioinspired "aplysinopsin cascade": total synthesis of (±)-tubastrindole B and related biosynthetic congeners.
    Organic letters, 2014, Oct-03, Volume: 16, Issue:19

    Topics: Alkaloids; Animals; Indoles; Marine Biology; Molecular Structure; Porifera; Stereoisomerism; Tryptophan

2014
Aplysinopsin-type and Bromotyrosine-derived Alkaloids from the South China Sea Sponge Fascaplysinopsis reticulata.
    Scientific reports, 2019, 02-19, Volume: 9, Issue:1

    Topics: A549 Cells; Alkaloids; Animals; Aquatic Organisms; China; Enzyme Inhibitors; Humans; Porifera; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Tryptophan; Tyrosine

2019
Anti-inflammatory potential of invasive sun corals (Scleractinia: Tubastraea spp.) from Brazil: alternative use for management?
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:4

    Topics: Alkaloids; Animals; Anthozoa; Anti-Inflammatory Agents; Brazil; Carrageenan; Cell Proliferation; Cell Survival; Edema; Hep G2 Cells; Humans; Lipopolysaccharides; Male; Mice; Models, Animal; Nitric Oxide; RAW 264.7 Cells; Tryptophan

2020
Anti-Leukemic Properties of Aplysinopsin Derivative EE-84 Alone and Combined to BH3 Mimetic A-1210477.
    Marine drugs, 2021, May-21, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Cell Cycle; Cell Death; Cell Line; Cytotoxins; Drug Synergism; Endoplasmic Reticulum Stress; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Myeloid Cell Leukemia Sequence 1 Protein; Sulfonamides; Tryptophan; Zebrafish

2021
Physicochemical, Interaction & Topological Descriptors vs. hMAO-A Inhibition of Aplysinopsin Analogs: A Boulevard to the Discovery of Semi-synthetic Antidepression Agents.
    Current drug metabolism, 2021, Volume: 22, Issue:11

    Topics: Antidepressive Agents; Computer Simulation; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship; Software; Tryptophan

2021