tryptophan has been researched along with anthranilic acid in 156 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (40.38) | 18.7374 |
| 1990's | 12 (7.69) | 18.2507 |
| 2000's | 25 (16.03) | 29.6817 |
| 2010's | 46 (29.49) | 24.3611 |
| 2020's | 10 (6.41) | 2.80 |
| Authors | Studies |
|---|---|
| Mantle, PG; Penn, J; Purcell, M | 1 |
| Baran, H; Schwarcz, R | 1 |
| Aparicio, C; Elmerich, C; Zimmer, W | 1 |
| Egorenkov, DA; Ignatov, VV; Iosipenko, AD; Katzy, EI; Panasenko, VI; Zhuravleva, EA | 1 |
| Abdel-Hamied, HA; Abdel-Tawab, GA; Aboul-Azm, T; Ebied, SA; el-Kholy, ZA; el-Sharaky, AS; el-Toukhy, MA | 1 |
| Odink, J; Schrijver, J; van der Poll, JM; Vink, M | 1 |
| Ishiguro, I; Naito, J; Ohta, Y; Sasaki, E; Shinohara, R | 1 |
| Boni, RL; Markey, SP; Naritsin, DB | 1 |
| Cohen, JD; Fink, GR; Normanly, J | 1 |
| Last, RL; Li, J | 1 |
| Lin, C; Paradkar, AS; Vining, LC | 1 |
| Goodman, CB; Heyliger, SO; Ngong, JM; Soliman, KF | 1 |
| Fujigaki, S; Fujii, H; Noma, A; Saito, K; Seishima, M; Takemura, M; Wada, H | 1 |
| Zook, M | 1 |
| Brudnik, VV; Bulkhin, NSh; Ignatov, VV; Shcherbakov, AA; Skripko, NG; Zakharova, EA | 1 |
| Amiridze, N; Brown, OR; Dale, WE; Dang, Y | 1 |
| Müller, A; Weiler, EW | 1 |
| Kim, C; Mills, SE; Nguyen-Huu, X; Spraggon, G; Yanofsky, C; Yee, MC | 1 |
| Ansari, MM; Sridhar, R | 1 |
| Buczko, W; Mysliwiec, P; Pawlak, D; Tankiewicz, A | 1 |
| Cohen, JD; Rapparini, F; Slovin, JP; Tam, YY | 1 |
| Byrne, KM; Ondeyka, JG; Smith, SK | 1 |
| Buczko, W; Malyszko, J; Mysliwiec, M; Pawlak, D; Pawlak, K | 1 |
| Bender, J; Quiel, JA | 1 |
| Baran, H; Draxler, M; Kepplinger, B; Nohl, H; Staniek, K; Stur, J | 1 |
| Bauby, H; Picardeau, M; Saint Girons, I | 1 |
| Chang, HK; Mohseni, P; Zylstra, GJ | 1 |
| HELLMANN, H; HILDINGER, M; LINGENS, F | 1 |
| TOMPSETT, SL | 1 |
| DOY, CH; RIVERA, A; SRINIVASAN, PR | 1 |
| FEDELE, L; QUAGLIARIELLO, E; TANCREDI, F | 1 |
| LESTER, G | 2 |
| GHOLSON, RK; HANKES, LV; HENDERSON, LM | 1 |
| LEPPANEN, VV; OKA, M | 1 |
| LIM, PG; MATELES, RI | 1 |
| DEMOSS, JA; MATCHETT, WH | 2 |
| FREUNDLICH, M; LICHSTEIN, HC | 1 |
| HELLSTROM, B; VASSELLA, F; WENGLE, B | 1 |
| ALIFANO, A; BUDILLON, G; COLTORTI, M; GADALETA, MN | 1 |
| NYC, JF; SOBOREN, J | 1 |
| BEHRMAN, EJ; STELLA, EJ | 1 |
| SPIERA, H | 1 |
| GINOULHIAC, E; TENCONI, LT | 1 |
| FARGIE, B; HODGINS, L; HOLLOWAY, BW | 1 |
| GIBSON, F; GIBSON, MI; MORGAN, PN | 1 |
| ALLEGRI, G; BENASSI, CA; PERISSINOTTO, B | 2 |
| CONTRERAS, E; CROXATTO, R; HUIDOBRO, F | 1 |
| GOEBEL, W; LINGENS, F; LUECK, W | 1 |
| DURKEE, AB; SIROIS, JC | 1 |
| ALLEGRI, G; BENASSI, CA; BENASSI, P; RABASSINI, A | 1 |
| CREPALDI, G; PARPAJOLA, A | 1 |
| MIYATAKE, M; SHIBA, S; TERAWAKI, A | 1 |
| SOMERVILLE, RL; YANOFSKY, C | 2 |
| MENCZYK, Z | 1 |
| BROWN, RR; HANKES, LV; LIPPINCOTT, S; SCHMAELER, M | 1 |
| ATKINSON, DE; KUPFER, D | 1 |
| BROWN, RR; FLINN, JH; PRICE, JM; YESS, N | 1 |
| CLAMP, JR; KOMROWER, GM; WESTALL, RG; WILSON, V | 1 |
| PALLERONI, NJ; STANIER, RY | 1 |
| BROWN, RR; BRYAN, GT; PRICE, JM | 2 |
| BROWN, RR; BRYAN, GT; MORRIS, CR; PRICE, JM | 1 |
| ALIFANO, A; ELICIO, MA; PAPA, S; QUAGLIARIELLO, E; TANCREDI, F | 1 |
| RATLEDGE, C | 1 |
| DOY, CH | 1 |
| ANDERSON, JA; DOEDEN, D; DRUMMOND, KN; GOOD, RA; MICHAEL, AF | 1 |
| HENDERSON, LM; MATHUR, GP; NG, CY | 1 |
| HATANAKA, M; HAYAISHI, O; KUNO, S; KURIHARA, N; NAKAJIMA, M; TANIUCHI, H | 1 |
| ABUL-FADL, MA; KHALAFALLAH, AS | 1 |
| AJL, SJ; MONTIE, TC | 1 |
| PINALS, RS | 1 |
| TENCONI, LT | 1 |
| IVANOVA, VD | 1 |
| GHOLSON, RK; HAYAISHI, O; ICHIYAMA, A; NISHIZUKA, Y | 1 |
| HAYAISHI, O; HONJO, T; ICHIYAMA, A; KAWAI, H; NAKAMURA, S; NISHIZUKA, Y; SENOH, S | 1 |
| CAREDDU, P; MAINARDI, L; TENCONI, LT | 1 |
| BEAVEN, V; KATZ, E; REDFIELD, B; WEISSBACH, H | 1 |
| WALSH, MP | 1 |
| Cerstiaens, A; De Loof, A; Huybrechts, J; Kotanen, S; Lebeau, I; Meylaers, K; Schoofs, L | 1 |
| HAYAISHI, O; STANIER, RY | 1 |
| Buczko, W; Chabielska, E; Pawlak, D; Tankiewicz, A; Topczewska-Bruns, J | 1 |
| Fukuoka, S; Fukuwatari, T; Ohsaki, S; Sasaki, R; Shibata, K; Suzuki, Y | 1 |
| Baker, EN; Goodfellow, C; Javid-Majd, F; Lee, CE; Shaun Lott, J | 1 |
| Omura, S; Tomoda, H; Uchida, R | 1 |
| Darlington, LG; Forrest, CM; Mackay, GM; Oxford, L; Stone, TW; Stoy, N | 1 |
| Farrow, JM; Pesci, EC | 1 |
| Buczko, P; Dziemiańczyk, D; Grabowska, SZ; Pawlak, D; Szarmach, IJ; Tankiewicz, A | 1 |
| Downs, DM; Ramos, I; Vivas, EI | 1 |
| HATZ, F; WISS, O | 1 |
| Liu, Z; Wang, W; Yuan, Q | 1 |
| Fukuwatari, T; Shibata, K | 3 |
| Fukuwatari, T; Okuno, A; Shibata, K | 1 |
| Backhaus, C; Hardeland, R; Laatsch, H; Rahman, H; Scheffler, S | 1 |
| RYDON, HN | 1 |
| AYRAULT, A; CHOPIN, J; RAOUL, Y | 1 |
| SCHWEIGERT, BS | 1 |
| Molina-Carballo, A; Muñoz-Hoyos, A; Romero, J; Uberos, J | 1 |
| Bien, B; Gulaj, E; Pawlak, D; Pawlak, K | 1 |
| Mujahid, M; Ramana, ChV; Sasikala, Ch | 1 |
| Nagata, Y; Nishiyama, E; Ohtsubo, Y; Tsuda, M; Yamamoto, Y | 1 |
| Du Preez, JL; Harvey, BH; Möller, M | 1 |
| Gao, X; Haynes, SW; Tang, Y; Walsh, CT | 1 |
| Kolodziej, L | 1 |
| Jorth, PA; Palmer, GC; Whiteley, M | 1 |
| Huang, Q; Lin, Y; Sun, X; Yan, Y; Yuan, Q | 1 |
| Eussen, SJ; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE | 1 |
| Fukuwatari, T; Hiratsuka, C; Saito, K; Sano, M; Sasaki, S; Shibata, K | 1 |
| Dijkhuis, A; Johnston, SL; Karlas, JA; Kulik, W; Lutter, R; Molenkamp, R; Smids, BS; Sterk, PJ; van de Pol, MA; van der Sluijs, KF; van der Zee, JS; van Eijk, HW; Wolthers, KC | 1 |
| Choi, MS; Gao, X; Houk, KN; Jiang, W; Jiménez-Osés, G; Tang, Y; Walsh, CT | 1 |
| Gregory, JF; Nijhout, HF; Reed, MC; Rios-Avila, L; Sitren, HS | 1 |
| Coleman, JP; Knoten, CA; Pesci, EC; Wells, G | 1 |
| Aalbers, MW; Aldenkamp, AP; Kessels, AG; Klinkenberg, S; Leenen, L; Majoie, HJ; Rijkers, K; van den Borne, CJ; Verschuure, P; Vles, JS | 1 |
| Beconi, M; Bonelli, F; Caretti, F; Chan, K; Dominguez, C; Herbst, T; Lyons, K; Monteagudo, E; Munoz-Sanjuan, I; Orsale, MV; Orsatti, L; Speziale, R; Toledo-Sherman, L; Veneziano, M; Zini, M | 1 |
| Brody, LC; Brosnan, JT; Brosnan, ME; Deac, OM; Fan, R; Gibney, ER; Laird, E; Midttun, Ø; Mills, JL; Molloy, AM; Shane, B; Ueland, PM; Wang, Y | 1 |
| Dierkes, J; Drevon, CA; Gudbrandsen, OA; Karlsson, T; Midttun, Ø; Nygård, O; Pedersen, ER; Strand, E; Ueland, PM; Øyen, J | 1 |
| Buttar, HS; Nayak, BN | 1 |
| Atkins, HS; Bancroft, GJ; Butt, A; Halliday, N; Titball, RW; Williams, P | 1 |
| Amador-Noguez, D; Choera, T; Keller, NP; Pisithkul, T; Wang, PM; Wiemann, P | 1 |
| Dabrowska, M; Jasiewicz, M; Kaminski, KA; Kazimierczyk, R; Knapp, M; Moniuszko, M; Musial, WJ; Pawlak, D; Rusak, M | 1 |
| Kaminski, T; Michalowska, M; Oksztulska-Kolanek, E; Pawlak, D; Znorko, B | 1 |
| Capi, M; Curto, M; Fazio, F; Giamberardino, MA; Lionetto, L; Martelletti, P; Negro, A; Nicoletti, F; Perugino, F; Simmaco, M | 1 |
| Capi, M; Curto, M; Fazio, F; Giamberardino, MA; Lionetto, L; Martelletti, P; Negro, A; Nicoletti, F; Simmaco, M | 1 |
| Budac, DP; Elfving, B; Eskelund, A; Sanchez, C; Wegener, G | 1 |
| Allorge, D; Bortolotti, P; Dessein, R; Faure, E; Faure, K; Grandjean, T; Guery, BP; Hennart, B; Jausions, G; Kipnis, E; Le Gouellec, A; Thepaut, M; Thieffry, C; Toussaint, B | 1 |
| Brimble, MA; Furkert, DP; Hume, PA; Kaur, H; Ngen, ST | 1 |
| Brody, LC; Deac, OM; Fan, R; Gardiner, CM; Lu, Z; McCann, A; Meyer, K; Midttun, Ø; Mills, JL; Molloy, AM; Quinn, L; Shane, B; Ueland, PM | 1 |
| Bezard, E; Camus, SM; Ceci, A; Fuertig, R; Hengerer, B; Luippold, AH | 1 |
| Cobb, SR; Dalton, RN; Darlington, LG; Forrest, CM; Kennedy, PG; Rodgers, J; Stone, TW; Turner, C | 1 |
| Ishihara, A; Kokubo, Y; Nishizaka, M; Taketa, S; Tebayashi, SI; Ube, N; Ueno, K; Yabuta, Y | 1 |
| Bengesser, SA; Birner, A; Dalkner, N; Fellendorf, FT; Fuchs, D; Hamm, C; Herzog-Eberhard, S; Kapfhammer, HP; Maget, A; Mangge, H; Moll, N; Pilz, R; Platzer, M; Queissner, R; Rauch, P; Reininghaus, B; Reininghaus, EZ; Schütze, G; Schwarz, M; Zelzer, S | 1 |
| Aspée, A; Dorta, E; González, L; Lissi, E; López-Alarcón, C; Pino, E | 1 |
| Del Rio-Chanona, EA; Jing, K; Ling, X; Tang, Y; Yao, C; Zhang, D | 1 |
| Kim, SK; Lee, JH; Li, XH | 1 |
| Bisaccia, M; Geist, L; Konrat, R; Lichtenecker, RJ; Schörghuber, J; Weber, F | 1 |
| An, FL; Liu, CQ; Lu, YH; Pan, ZH | 1 |
| Inglot, M; Laskus, T; Malyszczak, K; Pawlak, D; Pawlowski, T; Radkowski, M; Zalewska, M | 1 |
| Badawy, AA | 1 |
| Amore, M; Baldessarini, RJ; Berardelli, I; Curto, M; Erbuto, D; Forte, A; Girardi, P; Innamorati, M; Lionetto, L; Montebovi, F; Pompili, M; Serafini, G; Seretti, ME; Simmaco, M | 1 |
| Choi, SA; Jee, SH; Jung, KJ; Khan, A; Na, J; Pamungkas, AD; Park, YH | 1 |
| Baldessarini, RJ; Comparelli, A; Corigliano, V; Curto, M; Fazio, F; Ferracuti, S; Lionetto, L; Nicoletti, F; Simmaco, M | 1 |
| Allers, KA; Harkin, A; McLoughlin, DM; Ryan, KM | 1 |
| Boscaro, F; Calabresi, P; Di Filippo, M; Gaetani, L; Pieraccini, G; Romani, L; Zelante, T | 1 |
| Aslamkhan, AG; Bass, A; Bhatt, B; Garfinkel, I; Glaab, WE; LaFranco-Scheuch, L; Li, N; Loughlin, A; Miller, JR; Pacchione, S; Pearson, K; Reynolds, S; Solban, N; Styring, TG; Vu, H; Xu, Q; Zhou, H | 1 |
| Bugajska, J; Inglot, M; Janocha-Litwin, J; Malyszczak, K; Marciniak, D; Pawlak, D; Pawlowski, T; Zalewska, M | 1 |
| Di Pasquale, P; Dischinger, K; Dreger, P; Luft, T; Monteagudo, E; Müller-Tidow, C; Orsatti, L; Radujkovic, A; Speziale, R; Stiehl, T | 1 |
| Aziz, FN; Guillemin, GJ; Jusof, FF; Lim, CK; Raju, CS; Sekaran, SD; Soe, HJ | 1 |
| Lazarus, CM; Prommarit, K; Promsuk, G; Suttangkakul, A; Vuttipongchaikij, S; Wattana-Amorn, P; Wonnapinij, P | 1 |
| Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S | 1 |
| Berenbaum, F; Binvignat, M; Butte, AJ; Courties, A; Crema, MD; Emond, P; Klatzmann, D; Kloppenburg, M; Lefèvre, A; Maheu, E; Mariotti-Ferrandiz, E; Miao, B; Mifsud, F; Richette, P; Sellam, J; Sokol, H | 1 |
| Bechmann, N; Fröbel, D; Langner, M; Peitzsch, M; Stanke, D; Žygienė, G | 1 |
2 review(s) available for tryptophan and anthranilic acid
| Article | Year |
|---|---|
New insights into tryptophan and its metabolites in the regulation of bone metabolism.
Topics: Animals; Bone and Bones; Humans; Kynurenine; Melatonin; ortho-Aminobenzoates; Picolinic Acids; Quinolinic Acid; Serotonin; Tryptophan; Xanthurenates | 2015 |
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan | 2022 |
2 trial(s) available for tryptophan and anthranilic acid
| Article | Year |
|---|---|
Supplementing healthy women with up to 5.0 g/d of L-tryptophan has no adverse effects.
Topics: Adolescent; Adult; Biomarkers; Body Mass Index; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Humans; Kynurenic Acid; Kynurenine; Niacinamide; ortho-Aminobenzoates; Placebos; Tryptophan; Young Adult | 2013 |
The effects of vagus nerve stimulation on tryptophan metabolites in children with intractable epilepsy.
Topics: Adolescent; Affect; Biotransformation; Child; Child, Preschool; Double-Blind Method; Drug Resistance; Electrodes, Implanted; Epilepsy; Female; Humans; Kynurenine; Male; Metabolic Networks and Pathways; ortho-Aminobenzoates; Seizures; Treatment Outcome; Tryptophan; Vagus Nerve Stimulation | 2014 |
152 other study(ies) available for tryptophan and anthranilic acid
| Article | Year |
|---|---|
Biosynthesis of glyantrypine by Aspergillus clavatus.
Topics: Alkaloids; Amino Acids; Aspergillus; Glycine; ortho-Aminobenzoates; Quinazolines; Tryptophan | 1992 |
Evidence for the preferential production of 3-hydroxyanthranilic acid from anthranilic acid in the rat brain.
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Kynurenine; Male; Mixed Function Oxygenases; Organ Specificity; ortho-Aminobenzoates; Rats; Rats, Inbred Strains; Tryptophan | 1991 |
Relationship between tryptophan biosynthesis and indole-3-acetic acid production in Azospirillum: identification and sequencing of a trpGDC cluster.
Topics: Acetyltransferases; Amino Acid Sequence; Azospirillum brasilense; Base Sequence; Genes, Bacterial; Indoleacetic Acids; Molecular Sequence Data; Multigene Family; Mutagenesis, Insertional; Open Reading Frames; ortho-Aminobenzoates; Recombination, Genetic; Sequence Alignment; Sequence Homology, Nucleic Acid; Tryptophan | 1991 |
Involvement of Azospirillum brasilense plasmid DNA in the production of indole acetic acid.
Topics: Azospirillum brasilense; Chromatography, Thin Layer; DNA, Bacterial; Indoleacetic Acids; Mutation; ortho-Aminobenzoates; Plasmids; Rhizobium; Tryptophan | 1990 |
The correlation between certain tryptophan metabolites and the N-nitrosamine content in the urine of bilharzial bladder cancer patients.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aminohippuric Acids; Colorimetry; Humans; Indican; Kynurenic Acid; Kynurenine; Male; Middle Aged; Nitrosamines; ortho-Aminobenzoates; Schistosomiasis haematobia; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates | 1986 |
Influence of tryptophan loading on urinary excretion of anthranilic acid and 3-hydroxyanthranilic acid by men and women as determined by alkali flame ionization gas chromatography.
Topics: 3-Hydroxyanthranilic Acid; Adult; Anticonvulsants; Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Indicators and Reagents; Kinetics; Male; ortho-Aminobenzoates; Sex Factors; Tryptophan | 1986 |
Anthranilic acid metabolism in the isolated perfused rat liver: detection and determination of anthranilic acid and its related substances using high-performance liquid chromatography with electrochemical detection.
Topics: Animals; Bile; Biotransformation; Chromatography, High Pressure Liquid; Electrochemistry; Glucuronates; In Vitro Techniques; Liver; ortho-Aminobenzoates; Perfusion; Rats; Spectrometry, Fluorescence; Tryptophan | 1984 |
Pentafluorobenzylation method for quantification of acidic tryptophan metabolites using electron capture negative ion mass spectrometry.
Topics: Fluorobenzenes; Kynurenic Acid; Kynurenine; Mass Spectrometry; Molecular Structure; ortho-Aminobenzoates; Picolinic Acids; Quaternary Ammonium Compounds; Quinolinic Acid; Tryptophan; Xanthurenates | 1995 |
Arabidopsis thaliana auxotrophs reveal a tryptophan-independent biosynthetic pathway for indole-3-acetic acid.
Topics: Arabidopsis; Deuterium; Gas Chromatography-Mass Spectrometry; Genotype; Indoleacetic Acids; Light; Models, Biological; Nitrogen Isotopes; ortho-Aminobenzoates; Tryptophan | 1993 |
The Arabidopsis thaliana trp5 mutant has a feedback-resistant anthranilate synthase and elevated soluble tryptophan.
Topics: Amino Acid Sequence; Anthranilate Synthase; Arabidopsis; Base Sequence; Cloning, Molecular; Crosses, Genetic; Drug Resistance; Feedback; Gene Expression Regulation, Plant; Molecular Sequence Data; Mutagenesis; ortho-Aminobenzoates; Phenotype; Sequence Analysis, DNA; Tryptophan | 1996 |
Regulation of an anthranilate synthase gene in Streptomyces venezuelae by a trp attenuator.
Topics: Anthranilate Synthase; Anticonvulsants; Base Sequence; Blotting, Southern; Cloning, Molecular; Escherichia coli; Gene Deletion; Genes, Bacterial; Molecular Sequence Data; Open Reading Frames; ortho-Aminobenzoates; Phenotype; Pseudomonas; Streptomyces; Transformation, Genetic; Tryptophan | 1998 |
The analgesic effects of tryptophan and its metabolites in the rat.
Topics: Analgesics; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hypolipidemic Agents; Iron Chelating Agents; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Pain; Picolinic Acids; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Tryptophan; Xanthurenates | 1998 |
Species differences in L-tryptophan-kynurenine pathway metabolism: quantification of anthranilic acid and its related enzymes.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Enzyme Activation; Gerbillinae; Guinea Pigs; Humans; Hydrolases; Indoleamine-Pyrrole 2,3,-Dioxygenase; Injections, Intravenous; Kynurenine; Kynurenine 3-Monooxygenase; Macaca mulatta; Male; Mice; Mixed Function Oxygenases; ortho-Aminobenzoates; Rabbits; Rats; Species Specificity; Tryptophan; Tryptophan Oxygenase | 1998 |
Biosynthesis of camalexin from tryptophan pathway intermediates in cell-suspension cultures of Arabidopsis.
Topics: Arabidopsis; Ascomycota; Cells, Cultured; Indoles; Kinetics; ortho-Aminobenzoates; Plant Diseases; Thiazoles; Tryptophan | 1998 |
Biosynthesis of indole-3-acetic acid in Azospirillum brasilense. Insights from quantum chemistry.
Topics: Azospirillum brasilense; Chromatography, High Pressure Liquid; Indoleacetic Acids; Indoles; ortho-Aminobenzoates; Plant Growth Regulators; Quantum Theory; Thermodynamics; Tryptophan | 1999 |
Evidence that kynurenine pathway metabolites mediate hyperbaric oxygen-induced convulsions.
Topics: Animals; Coma; Enzyme Inhibitors; Hyperbaric Oxygenation; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; ortho-Aminobenzoates; Rats; Rats, Sprague-Dawley; Seizures; Sulfonamides; Thiazoles; Time Factors; Tryptophan | 2000 |
Indolic constituents and indole-3-acetic acid biosynthesis in the wild-type and a tryptophan auxotroph mutant of Arabidopsis thaliana.
Topics: Arabidopsis; Gas Chromatography-Mass Spectrometry; Glycerophosphates; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; ortho-Aminobenzoates; Spectrometry, Mass, Electrospray Ionization; Tritium; Tryptophan | 2000 |
The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan.
Topics: Amino Acid Sequence; Anthranilate Synthase; Base Sequence; Binding Sites; Chorismic Acid; Crystallography, X-Ray; Cyclohexenes; DNA, Bacterial; Glutamic Acid; Glutamine; Lyases; Molecular Sequence Data; Nitrogenous Group Transferases; Oligopeptides; ortho-Aminobenzoates; Protein Structure, Secondary; Serratia marcescens; Substrate Specificity; Tryptophan | 2001 |
Some tryptophan pathways in the phytopathogen Xanthomonas oryzae pv. oryzae.
Topics: Catechols; Chromatography, High Pressure Liquid; Indoleacetic Acids; Kynurenine; ortho-Aminobenzoates; Plant Diseases; Tryptophan; Xanthomonas | 2000 |
Tryptophan metabolism via the kynurenine pathway in experimental chronic renal failure.
Topics: Animals; Chromatography, High Pressure Liquid; Creatinine; Kidney; Kidney Failure, Chronic; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Wistar; Time Factors; Tryptophan; Urea; Xanthurenates | 2002 |
Indole-3-acetic acid metabolism in Lemna gibba undergoes dynamic changes in response to growth temperature.
Topics: Carbon Radioisotopes; Indoleacetic Acids; Magnoliopsida; Nitrogen Radioisotopes; ortho-Aminobenzoates; Temperature; Tritium; Tryptophan | 2002 |
Biosynthesis of nodulisporic acid A: precursor studies.
Topics: Acetates; Ascomycota; Carbon Radioisotopes; Indoles; Isotope Labeling; Mevalonic Acid; Nuclear Magnetic Resonance, Biomolecular; ortho-Aminobenzoates; Ribose; Tryptophan | 2002 |
Accumulation of toxic products degradation of kynurenine in hemodialyzed patients.
Topics: Female; Humans; Kidney; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Quinolinic Acid; Renal Dialysis; Tryptophan; Uremia; Xanthurenates | 2001 |
Glucose conjugation of anthranilate by the Arabidopsis UGT74F2 glucosyltransferase is required for tryptophan mutant blue fluorescence.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Base Sequence; Cloning, Molecular; DNA Primers; Genes, Plant; Genotype; Glucose; Glucosyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; ortho-Aminobenzoates; Polymerase Chain Reaction; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Tryptophan | 2003 |
Kynurenines and the respiratory parameters on rat heart mitochondria.
Topics: 3-Hydroxyanthranilic Acid; Animals; Free Radical Scavengers; In Vitro Techniques; Kinetics; Kynurenine; Male; Mitochondria, Heart; Mitochondrial Proteins; NAD; ortho-Aminobenzoates; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Succinates; Tryptophan | 2003 |
Construction and complementation of the first auxotrophic mutant in the spirochaete Leptospira meyeri.
Topics: Anthranilate Synthase; Base Sequence; Drug Resistance, Bacterial; Escherichia coli; Genetic Complementation Test; Genetic Vectors; Kanamycin; Leptospira; Molecular Sequence Data; Mutation; Nitrogenous Group Transferases; ortho-Aminobenzoates; Recombination, Genetic; Tryptophan | 2003 |
Characterization and regulation of the genes for a novel anthranilate 1,2-dioxygenase from Burkholderia cepacia DBO1.
Topics: Bacterial Proteins; Burkholderia cepacia; Cloning, Molecular; Gene Expression Regulation, Bacterial; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; ortho-Aminobenzoates; Restriction Mapping; Sequence Analysis, DNA; Substrate Specificity; Tryptophan | 2003 |
[N-(o-carboxyphenyl)-fructosylamine (fructosyl-anthranilic acid), a possible by-product of tryptophan biosynthesis in Salmonella typhimurium].
Topics: Aminobenzoates; Carbohydrate Metabolism; Fructose; ortho-Aminobenzoates; Salmonella; Salmonella typhimurium; Tryptophan | 1958 |
The determination in urine of some metabolites of tryptophankynurenine, anthranilic acid and 3-hydroxyanthranilic acid- and reference to the presence of o-aminophenol in urine.
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Aminophenols; Humans; Kynurenine; ortho-Aminobenzoates; Phenols; Tryptophan | 1959 |
Evidence for the enzymatic synthesis of N-(5'-phosphoribosyl) anthranilic acid, a new intermediate in tryptophan biosynthesis.
Topics: Enzymes; ortho-Aminobenzoates; Tryptophan | 1961 |
[Possibility of diagnosis of tumors of the bladder by chromatographic revelation of metabolites of the tryptophan-nicotinic acid interrelation].
Topics: Humans; Kynurenine; Niacin; ortho-Aminobenzoates; Tryptophan; Urinary Bladder Neoplasms; Urine | 1960 |
Repression and inhibition of indole-synthesizing activity in Neurospora crassa.
Topics: Indoles; Neurospora; Neurospora crassa; ortho-Aminobenzoates; Tryptophan | 1961 |
3-Hydroxyanthranilic acid as an intermediate in the oxidation of the indole nucleus of tryptophan.
Topics: 3-Hydroxyanthranilic Acid; Indoles; ortho-Aminobenzoates; Tryptophan | 1960 |
Metabolism of tryptophan in cancer of various sites.
Topics: Indoleacetic Acids; Kynurenine; Neoplasms; ortho-Aminobenzoates; Tryptophan; Xanthurenates | 1963 |
Regulation of early reactions in the biosynthesis of tryptophan in Neurospora crassa.
Topics: Glycerophosphates; Indoleacetic Acids; Neurospora; Neurospora crassa; ortho-Aminobenzoates; Tryptophan | 1963 |
Tryptophan- and indole-excreting bacterial mutants.
Topics: Escherichia coli; Indoles; ortho-Aminobenzoates; Tryptophan | 1963 |
Direct evidence for a trytophan-anthranilic acid cycle in Neurospora.
Topics: Neurospora; ortho-Aminobenzoates; Tryptophan | 1963 |
Tryptophanase-tryptophan synthetase systems in Escherichia coli. I. Effect of tryptophan and related compounds.
Topics: Escherichia coli; Hydrolases; Indoleacetic Acids; Indoles; Ligases; Lyases; ortho-Aminobenzoates; Tryptophan; Tryptophan Synthase; Tryptophanase | 1962 |
Urinary excretion of tryptophan metabolites in the healthy infant.
Topics: Chromatography; Humans; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Tryptophan; Urine | 1962 |
[Tryptophan conversion to nicotinic acid in mice with Friend's leukemia. I. 3-Hydroxyanthranilic acid oxidase activity].
Topics: Animals; Friends; Leukemia; Leukemia, Experimental; Mice; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Oxidoreductases; Tryptophan | 1962 |
EFFECTS OF CERTAIN AMINO ACIDS ON ANTHRANILATE PRODUCTION IN NEUROSPORA CRASSA.
Topics: Amino Acids; Arginine; Aspartic Acid; Chromatography; Fluorescence; Leucine; Metabolism; Methionine; Neurospora; Neurospora crassa; ortho-Aminobenzoates; Phenylalanine; Proline; Tryptophan; Tyrosine | 1963 |
ENRICHMENT PROCEDURES FOR THE ISOLATION OF TRYPTOPHAN-OXIDIZING ORGANISMS.
Topics: Culture Media; Kynurenic Acid; ortho-Aminobenzoates; Oxidation-Reduction; Pseudomonas; Tryptophan | 1963 |
EXCRETION OF A TRYPTOPHAN METABOLITE IN RHEUMATOID ARTHRITIS.
Topics: Arthritis, Rheumatoid; Humans; ortho-Aminobenzoates; Proteins; Tryptophan; Urine | 1963 |
[INFLUENCE OF TRYPTOPHAN-PYRROLASE-INDUCING STIMULI ON THE 3-OH-ANTHRANILIC-OXIDASE ACTIVITY OF THE LIVER AND KIDNEY IN RATS].
Topics: Kidney; Liver; Metabolism; ortho-Aminobenzoates; Oxidoreductases; Rats; Research; Tryptophan; Tryptophan Oxygenase | 1963 |
UNLINKED LOCI AFFECTING RELATED BIOSYNTHETIC STEPS IN PSEUDOMONAS AERUGINOSA.
Topics: Bacterial Proteins; Bacteriophages; Cystine; Indoles; Leucine; Metabolism; Methionine; Microbiology; ortho-Aminobenzoates; Proteins; Pseudomonas aeruginosa; Research; Tryptophan | 1963 |
THE CONVERSION OF SHIKIMIC ACID INTO CERTAIN AROMATIC COMPOUNDS BY CELL-FREE EXTRACTS OF AEROBACTER AEROGENES AND ESCHERICHIA COLI.
Topics: Adenosine Triphosphate; Chromatography; Enterobacter aerogenes; Escherichia coli; Metabolism; NAD; ortho-Aminobenzoates; Phenylpyruvic Acids; Pyruvates; Research; Shikimic Acid; Spectrophotometry; Tryptophan | 1963 |
THE METABOLISM OF TRYPTOPHAN IN PATIENTS WITH BLADDER CANCER AND OTHER UROLOGICAL DISEASES.
Topics: Geriatrics; Humans; Kidney Neoplasms; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Prostatic Neoplasms; Proteins; Tryptophan; Urinary Bladder Diseases; Urinary Bladder Neoplasms; Urine | 1963 |
STUDIES ON MORPHINE. III. ACTION OF METABOLIC PRECURSORS TO SEROTONIN AND NORADRENALINE AND RELATED SUBSTANCES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Ergot Alkaloids; Iproniazid; Kynurenine; Lysergic Acid Diethylamide; Methyldopa; Mice; Morphine; Nalorphine; Norepinephrine; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Research; Serotonin; Shikimic Acid; Toxicology; Tryptophan; Tyrosine | 1963 |
[ON A NITROGEN-CONTAINING PRIMARY PRODUCT OF ANTHRANILIC ACID IN THE TRYPTOPHAN BIOSYNTHESIS OF SACCHAROMYCES CEREVISIAE].
Topics: Biochemical Phenomena; Nitrogen; ortho-Aminobenzoates; Saccharomyces; Saccharomyces cerevisiae; Tryptophan | 1963 |
THE DETECTION OF SOME INDOLES AND RELATED COMPOUNDS ON PAPER CHROMATOGRAMS.
Topics: 4-Aminobenzoic Acid; Amino Acids; Chromatography; Citrulline; Indicators and Reagents; Indoleacetic Acids; Indoles; Kynurenine; ortho-Aminobenzoates; Phenols; Quinolines; Research; Thiourea; Tryptophan; Urea; Xanthurenates | 1964 |
TRYPTOPHAN METABOLISM IN SPECIAL PAIRS OF TWINS.
Topics: Chromatography; Diseases in Twins; Genetics, Medical; Kynurenic Acid; Kynurenine; Metabolic Diseases; ortho-Aminobenzoates; Proteins; Schizophrenia; Spectrophotometry; Tryptophan; Urine; Xanthurenates | 1964 |
EXCRETION OF TRYPTOPHAN METABOLITES IN DIFFERENT FORMS OF HAEMOBLASTOSIS.
Topics: Cortisone; Cyclophosphamide; Genetic Diseases, X-Linked; Hodgkin Disease; Humans; Kynurenic Acid; Kynurenine; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphatic Diseases; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mechlorethamine; Multiple Myeloma; ortho-Aminobenzoates; Phenylbutazone; Polycythemia Vera; Proteins; Pyridoxal Phosphate; Pyridoxine; Sarcoma; Severe Combined Immunodeficiency; Tryptophan; Urine; Xanthurenates | 1964 |
STUDIES ON THE TRYPTOPHAN METABOLISM IN TUMOR-BEARING ANIMALS.
Topics: Animals; Kynurenic Acid; Kynurenine; Liver; Neoplasms; Neoplasms, Experimental; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Proteins; Rats; Research; Sarcoma; Tryptophan; Urine; Xanthurenates | 1964 |
ON THE TRANSLATION OF THE A GENE REGION OF TRYPTOPHAN MESSENGER RNA.
Topics: Bacterial Proteins; Carbon Isotopes; Escherichia coli; Genetics; Leucine; Ligases; Mutation; Nucleoproteins; ortho-Aminobenzoates; Proteins; Research; Ribosomes; RNA; RNA, Bacterial; RNA, Messenger; Tryptophan | 1964 |
A METHOD FOR THE DETERMINATION OF EIGHT TRYPTOPHAN METABOLITES IN BIOLOGICAL FLUIDS.
Topics: Blood Proteins; Cerebrospinal Fluid Proteins; Chromatography; Humans; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Spectrophotometry; Tryptophan; Urine; Xanthurenates | 1964 |
METABOLISM OF 3-HYDROXYANTHRANILIC ACID-CARBOXYL-C14 IN THE HUMAN.
Topics: 3-Hydroxyanthranilic Acid; Achondroplasia; Blood; Carbon Isotopes; Chromatography; Hippurates; Humans; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Rats; Research; Tryptophan; Urine; Xanthurenates | 1964 |
PHYSIOLOGICAL CHANNELING OF TRYPTOPHAN IN NEUROSPORA CRASSA.
Topics: Carbon Isotopes; Culture Media; Indoles; Mutation; Neurospora; Neurospora crassa; ortho-Aminobenzoates; Perchlorates; Proteins; Research; Tryptophan | 1964 |
QUANTITATIVE METHOD FOR DETERMINATION OF INDOLE, TRYPTOPHAN, AND ANTHRANILIC ACID IN THE SAME ALIQUOT.
Topics: Colorimetry; Indoles; Iodides; Lactobacillus; Nitrites; ortho-Aminobenzoates; Research; Spectrophotometry; Thiosulfates; Tryptophan | 1964 |
URINARY EXCRETION OF TRYPTOPHAN METABOLITES IN PATIENTS WITH RENAL PELVIS AND PARENCHYMA TUMOURS.
Topics: Chromatography; Humans; Kidney Neoplasms; Kidney Pelvis; Kynurenic Acid; Kynurenine; Neoplasms; ortho-Aminobenzoates; Spectrophotometry; Tryptophan; Urine; Xanthurenates | 1964 |
EXCRETION OF TRYPTOPHAN METABOLITES BY PATIENTS WITH RHEUMATOID ARTHRITIS.
Topics: Arthritis; Arthritis, Rheumatoid; Biomedical Research; Chromatography; Gout; Hippurates; Indoles; Kynurenic Acid; Kynurenine; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Proteins; Psoriasis; Pyridines; Pyridoxine; Spondylitis; Tryptophan; Urine; Xanthurenates | 1964 |
HYDROXYKYNURENINURIA: A CASE OF ABNORMAL TRYPTOPHAN METABOLISM PROBABLY DUE TO A DEFICIENCY OF KYNURENINASE.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Chromatography; Electrophoresis; Humans; Hydrolases; Kynurenic Acid; Kynurenine; Metabolic Diseases; Niacin; ortho-Aminobenzoates; Proteins; Pyridoxine; Spectrophotometry; Tryptophan; Urine; Xanthurenates | 1964 |
REGULATORY MECHANISMS GOVERNING SYNTHESIS OF THE ENZYMES FOR TRYPTOPHAN OXIDATION BY PSEUDOMONAS FLUORESCENS.
Topics: Amidohydrolases; Catechols; Enzymes; Hydrolases; Kynurenine; Lactones; ortho-Aminobenzoates; Proteins; Pseudomonas; Pseudomonas fluorescens; Pyrroles; Tryptophan | 1964 |
INCIDENCE OF MOUSE BLADDER TUMORS FOLLOWING IMPLANTATION OF PARAFFIN PELLETS CONTAINING CERTAIN TRYPTOPHAN METABOLITES.
Topics: Animals; Carcinogens; Chromatography; Incidence; Kynurenic Acid; Mice; Neoplasms; Neoplasms, Experimental; ortho-Aminobenzoates; Paraffin; Quinolines; Research; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates | 1964 |
IN VIVO ELUTION OF TRYPTOPHAN METABOLITES AND OTHER AROMATIC NITROGEN COMPOUNDS FROM CHOLESTEROL PELLETS IMPLANTED INTO MOUSE BLADDERS.
Topics: Amines; Animals; Carcinogens; Cholesterol; Fluorenes; Hydroxylamines; Kynurenic Acid; Kynurenine; Metabolism; Mice; Naphthalenes; Nitrogen; Nitrogen Compounds; ortho-Aminobenzoates; Pharmacology; Quinolines; Research; Stearic Acids; Tryptophan; Urinary Bladder; Urinary Bladder Neoplasms; Xanthurenates | 1964 |
MOUSE BLADDER CARCINOGENICITY OF CERTAIN TRYPTOPHAN METABOLITES AND OTHER AROMATIC NITROGEN COMPOUNDS SUSPENDED IN CHOLESTEROL.
Topics: Amines; Animals; Carcinogens; Cholesterol; Fluorenes; Hydroxylamines; Kynurenic Acid; Kynurenine; Metabolism; Mice; Naphthalenes; Neoplasms; Neoplasms, Experimental; Nitrogen; Nitrogen Compounds; ortho-Aminobenzoates; Pharmacology; Quinolines; Research; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates | 1964 |
TRYPTOPHAN-NICOTINIC ACID METABOLISM IN PATIENTS WITH TUMOURS OF THE BLADDER AND KIDNEY.
Topics: Amino Acids; Biomedical Research; Humans; Kidney Neoplasms; Metabolism; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Tryptophan; Urinary Bladder Neoplasms; Urine | 1964 |
RELATIONSHIP BETWEEN THE PRODUCTS OF AROMATIC BIOSYNTHESIS IN MYCOBACTERIUM SMEGMATIS AND AEROBACTER AEROGENES.
Topics: Benzoates; Culture Media; Enterobacter aerogenes; Escherichia coli; Iron; Metabolism; Mycobacterium; Mycobacterium smegmatis; ortho-Aminobenzoates; Quinic Acid; Research; Shikimic Acid; Tryptophan | 1964 |
THE BIOCHEMICAL DIFFERENCE BETWEEN CERTAIN PHENOTYPICALLY SIMILAR, BUT GENOTYPICALLY DIFFERENT, TRYPTOPHAN AUXOTROPHS OF PSEUDOMONAS AERUGINOSA.
Topics: Amino Acids; Enterobacter aerogenes; Enzyme Inhibitors; Enzyme Repression; Escherichia coli; Molecular Biology; Mutation; ortho-Aminobenzoates; Pseudomonas aeruginosa; Research; Tryptophan; Ultraviolet Rays | 1964 |
TRYPTOPHAN METABOLISM IN MAN.
Topics: Amino Acid Metabolism, Inborn Errors; Calcium; Child; Glucuronates; Humans; Indican; Indoleacetic Acids; Intestinal Absorption; Kynurenine; Male; Metabolism; ortho-Aminobenzoates; p-Aminohippuric Acid; Pyridines; Tryptophan; Urine; Xanthurenates | 1964 |
THE SYNTHESIS AND METABOLISM OF DL-TRYPTOPHAN-5-14C.
Topics: Acetates; Alanine; Amino Acids; Anilides; Benzoates; Glutamates; Glutarates; Lipid Metabolism; Liver; Liver Glycogen; Nucleic Acids; ortho-Aminobenzoates; Protein Hydrolysates; Rats; Research; Tryptophan | 1964 |
ENZYMATIC FORMATION OF CATECHOL FROM ANTHRANILIC ACID.
Topics: Benzene; Benzoates; Carbon Isotopes; Catechols; Glycols; Kynurenic Acid; Levulinic Acids; Metabolism; Mixed Function Oxygenases; NAD; NADP; ortho-Aminobenzoates; Oxidoreductases; Pseudomonas; Research; Salicylic Acid; Tryptophan | 1964 |
STUDIES ON THE URINARY EXCRETION OF CERTAIN TRYPTOPHAN METABOLITES BEFORE AND AFTER TRYPTOPHAN LOADING DOSE IN BILHARZIASIS, BILHARZIAL BLADDER CANCER AND CERTAIN OTHER TYPES OF MALIGNANCIES IN EGYPT.
Topics: Amino Acids; Egypt; Epidemiology; Fluids and Secretions; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Neoplasms; ortho-Aminobenzoates; Schistosomiasis; Tryptophan; Urinary Bladder Neoplasms; Urine; Xanthurenates | 1964 |
SELECTIVE INHIBITION BY TRYPTOPHAN ANALOGUES OF MURINE TOXIN SYNTHESIS IN PASTEURELLA PESTIS.
Topics: Animals; Antitoxins; Electrophoresis; Indoles; Metabolism; Mice; ortho-Aminobenzoates; Pharmacology; Proteins; Research; Shikimic Acid; Toxins, Biological; Tryptophan; Yersinia pestis | 1964 |
TRYPTOPHAN METABOLISM IN RHEUMATIC DISEASE.
Topics: Amino Acids; Arthritis; Arthritis, Rheumatoid; Chromatography; Humans; Kynurenic Acid; Kynurenine; Lupus Erythematosus, Systemic; ortho-Aminobenzoates; Rheumatic Diseases; Scleroderma, Systemic; Tryptophan; Urine; Xanthurenates | 1964 |
[URINARY ELIMINATION OF METABOLITES OF THE TRYPTOPHAN--NICOTINE ACID PATHWAY IN DIABETES DUE TO PANCREATECTOMY IN THE RAT].
Topics: Diabetes Mellitus; Metabolism; Niacin; Nicotine; ortho-Aminobenzoates; Pancreatectomy; Pyridines; Rats; Research; Tryptophan; Urine | 1964 |
DISORDERS OF TRYPTOPHAN METABOLISM IN LEUKAEMIA.
Topics: Amino Acids; Child; Humans; Indoles; Kynurenine; Leukemia; ortho-Aminobenzoates; Tryptophan | 1964 |
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. I. ENZYMIC FORMATION OF GLUTARIC ACID FROM 3-HYDROXYANTHRANILIC ACID.
Topics: 3-Hydroxyanthranilic Acid; Amino Acids; Animals; Benzene; Carbon Dioxide; Carbon Isotopes; Cats; Chromatography; Coenzyme A; Electrophoresis; Glutarates; Keto Acids; Kynurenine; Liver; Metabolism; NAD; ortho-Aminobenzoates; Pseudomonas; Pyridines; Research; Tryptophan | 1965 |
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. II. ENZYMIC FORMATION OF ALPHA-AMINOMUCONIC ACID FROM 3-HYDROXYANTHRANILIC ACID.
Topics: 3-Hydroxyanthranilic Acid; Acids; Aldehydes; Animals; Benzene; Carboxy-Lyases; Cats; Chromatography; Dicarboxylic Acids; Edetic Acid; Electrophoresis; Hydrogen-Ion Concentration; Liver; Metabolism; NAD; ortho-Aminobenzoates; Oxidoreductases; Pyridines; Research; Tryptophan | 1965 |
[RESEARCH ON ELIMINATION OF METABOLITES OF THE TRYPTOPHAN TO NICOTINIC ACID PATHWAY IN INFANTS].
Topics: Chromatography; Diet; Hippurates; Humans; Infant; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Tryptophan; Urine; Vitamins; Xanthurenates | 1964 |
STUDIES ON THE REGULATION OF TRYPTOPHAN BIOSYNTHESIS IN ESCHERICHIA COLI.
Topics: Amino Acids; Bacterial Proteins; Culture Media; Drug Resistance; Drug Resistance, Microbial; Escherichia coli; Feedback; Genes; Hydro-Lyases; Ligases; Mutation; ortho-Aminobenzoates; Proteins; Research; Tryptophan | 1965 |
4-METHYL-3-HYDROXYANTHRANILIC ACID, AN INTERMEDIATE IN ACTINOMYCIN BIOSYNTHESIS.
Topics: Amino Acids; Chromatography; Dactinomycin; Kynurenine; Metabolism; ortho-Aminobenzoates; Pharmacology; Research; Streptomyces; Tryptophan; Valine | 1965 |
SEPARATION AND ESTIMATION OF TRYPTOPHAN-NICOTINIC ACID METABOLITES IN URINE BY THIN-LAYER CHROMATOGRAPHY.
Topics: Azo Compounds; Chromatography; Chromatography, Thin Layer; Colorimetry; Humans; Indicators and Reagents; Kynurenine; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Tryptophan; Urine; Xanthurenates | 1965 |
Neurotoxic and neurobehavioral effects of kynurenines in adult insects.
Topics: Animals; Apoptosis; Behavior, Animal; Cell Survival; Cells, Cultured; Diptera; Dose-Response Relationship, Drug; Grasshoppers; Insecta; Kynurenine; Lethal Dose 50; Nervous System; Neurons; Neurotoxicity Syndromes; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan | 2003 |
The bacterial oxidation of tryptophan. II. Defective metabolism of anthranilic acid.
Topics: Aminobenzoates; Bacteria; ortho-Aminobenzoates; Oxidation-Reduction; Tryptophan | 1951 |
Kynurenine metabolism in central nervous system in experimental chronic renal failure.
Topics: Animals; Central Nervous System; Central Nervous System Diseases; Kidney Failure, Chronic; Kynurenine; Male; ortho-Aminobenzoates; Rats; Rats, Wistar; Tissue Distribution; Tryptophan | 2003 |
The effects of phthalate esters on the tryptophan-niacin metabolism.
Topics: 3-Hydroxyanthranilic Acid; Animals; Dibutyl Phthalate; Diethylhexyl Phthalate; Kynurenic Acid; Liver; Male; NAD; Niacin; ortho-Aminobenzoates; Phthalic Acids; Plasticizers; Rats; Rats, Wistar; Tryptophan; Xanthurenates | 2003 |
The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate.
Topics: Amino Acid Sequence; Anthranilate Phosphoribosyltransferase; Benzamidines; Binding Sites; Catalysis; Cations, Divalent; Conserved Sequence; Crystallography, X-Ray; Lung; Magnesium; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; ortho-Aminobenzoates; Phosphoribosyl Pyrophosphate; Protein Structure, Tertiary; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan | 2006 |
Biosynthesis of sespendole.
Topics: Acetates; Diterpenes; Fungi; Indoles; Nuclear Magnetic Resonance, Biomolecular; ortho-Aminobenzoates; Tryptophan | 2006 |
Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment.
Topics: 3-Hydroxyanthranilic Acid; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethacin; Kynurenic Acid; Kynurenine; Lipid Peroxidation; Male; Middle Aged; Molecular Structure; Neopterin; ortho-Aminobenzoates; Osteoporosis; Sodium Salicylate; Tryptophan | 2006 |
Two distinct pathways supply anthranilate as a precursor of the Pseudomonas quinolone signal.
Topics: Antibiosis; Artificial Gene Fusion; beta-Galactosidase; Chorismic Acid; Gene Deletion; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Kynurenine; Metabolic Networks and Pathways; Microbial Viability; Models, Biological; ortho-Aminobenzoates; Pseudomonas aeruginosa; Quinolones; Staphylococcus aureus; Tryptophan | 2007 |
Tryptophan and its metabolites in patients with oral squamous cell carcinoma: preliminary study.
Topics: Aged, 80 and over; Carcinoma, Squamous Cell; Chromatography, High Pressure Liquid; Female; Humans; Kynurenic Acid; Male; Middle Aged; Mouth Neoplasms; ortho-Aminobenzoates; Saliva; Tryptophan | 2006 |
Mutations in the tryptophan operon allow PurF-independent thiamine synthesis by altering flux in vivo.
Topics: Anthranilate Phosphoribosyltransferase; Anthranilate Synthase; Bacterial Proteins; Culture Media; Models, Molecular; Mutation; Operon; ortho-Aminobenzoates; Ribosemonophosphates; Salmonella typhimurium; Thiamine; Tryptophan | 2008 |
About the breakdown of tryptophan to alanine and anthranilic acid in the animal organism.
Topics: Alanine; ortho-Aminobenzoates; Tryptophan | 1949 |
Biosynthesis of [1-15N] L-tryptophan from 15N labeled anthranilic acid by fermentation of Candida utilis mutant.
Topics: Candida; Molecular Structure; Mutation; Nitrogen Isotopes; ortho-Aminobenzoates; Tryptophan | 2009 |
Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans.
Topics: 3-Hydroxyanthranilic Acid; Adult; Chromatography, High Pressure Liquid; Feedback, Physiological; Female; Humans; Kynurenic Acid; Niacinamide; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan; Xanthurenates | 2007 |
Urinary excretory ratio of anthranilic acid/kynurenic acid as an index of the tolerable amount of tryptophan.
Topics: Animals; Dietary Supplements; Dose-Response Relationship, Drug; Kynurenic Acid; Male; ortho-Aminobenzoates; Rats; Rats, Wistar; Tryptophan | 2008 |
NO scavenging by 3-hydroxyanthranilic acid and 3-hydroxykynurenine: N-nitrosation leads via oxadiazoles to o-quinone diazides.
Topics: 3-Hydroxyanthranilic Acid; Acetylcysteine; Aminophenols; Chromatography, Thin Layer; Diazonium Compounds; Free Radical Scavengers; Hydrazines; Inflammation; Kynurenine; Magnetic Resonance Imaging; Mass Spectrometry; Nitric Oxide; Nitrites; Nitrosation; Nuclear Magnetic Resonance, Biomolecular; ortho-Aminobenzoates; Oxadiazoles; Quinones; Tryptophan | 2008 |
Anthranilic acid as an intermediate in the biosynthesis of tryptophan by Bact. typhosum.
Topics: ortho-Aminobenzoates; Tryptophan | 1948 |
Action on Bacillus coli of the naphthalene isostere of tryptophan and action of anthranillic acid.
Topics: Escherichia coli; ortho-Aminobenzoates; Tryptophan | 1947 |
The role of vitamin B6 in the synthesis of tryptophane from indole and anthranilic acid by Lactobacillus arabinosus.
Topics: Bacteria; Indoles; Lactic Acid; Lactobacillus; ortho-Aminobenzoates; Pyridoxine; Tryptophan; Vitamin B 6 | 1947 |
Melatonin and elimination of kynurenines in children with Down's syndrome.
Topics: Child; Child, Preschool; Circadian Rhythm; Down Syndrome; Female; Humans; Kynurenic Acid; Kynurenine; Male; Melatonin; ortho-Aminobenzoates; Oxidative Stress; Serotonin; Tryptophan | 2010 |
Kynurenine and its metabolites in Alzheimer's disease patients.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Chromatography, High Pressure Liquid; Female; Humans; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan | 2010 |
Aniline-induced tryptophan production and identification of indole derivatives from three purple bacteria.
Topics: Aniline Compounds; Betaproteobacteria; Biodegradation, Environmental; Chromatography, High Pressure Liquid; Chromatography, Liquid; Indoleacetic Acids; Indoles; Industrial Waste; Mass Spectrometry; Metabolic Networks and Pathways; ortho-Aminobenzoates; Rhodobacter sphaeroides; Rhodospirillum rubrum; Tandem Mass Spectrometry; Tryptophan | 2010 |
Pivotal role of anthranilate dioxygenase genes in the adaptation of Burkholderia multivorans ATCC 17616 in soil.
Topics: Adaptation, Physiological; Bacterial Proteins; Burkholderia; Gene Expression Profiling; Mixed Function Oxygenases; ortho-Aminobenzoates; Promoter Regions, Genetic; Repressor Proteins; Soil Microbiology; Stress, Physiological; Tryptophan | 2012 |
Development and validation of a single analytical method for the determination of tryptophan, and its kynurenine metabolites in rat plasma.
Topics: 3-Hydroxyanthranilic Acid; Animals; Charcoal; Chromatography, High Pressure Liquid; Depression; Kynurenic Acid; Kynurenine; Linear Models; Male; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Schizophrenia; Social Isolation; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptophan | 2012 |
Assembly of asperlicin peptidyl alkaloids from anthranilate and tryptophan: a two-enzyme pathway generates heptacyclic scaffold complexity in asperlicin E.
Topics: Alkaloids; Benzodiazepinones; Biocatalysis; Mixed Function Oxygenases; Molecular Conformation; ortho-Aminobenzoates; Peptides; Tryptophan | 2012 |
The metabolites in the tryptophan degradation pathway might be useful to determine the tolerable upper intake level of tryptophan intake in rats.
Topics: Adult; Animals; Female; Humans; Kynurenic Acid; Male; Niacinamide; No-Observed-Adverse-Effect Level; Nutritional Requirements; ortho-Aminobenzoates; Rats; Rats, Wistar; Tryptophan; Vitamins | 2012 |
An exploratory study of the interplay between decreased concentration of tryptophan, accumulation of kynurenines, and inflammatory arthritis.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Arthritis, Experimental; Gene Expression Regulation; Hydrolases; Inflammation; Kynurenine; Kynurenine 3-Monooxygenase; Lymph Nodes; Mice; Mice, Inbred DBA; Organ Specificity; ortho-Aminobenzoates; RNA, Messenger; Signal Transduction; Spleen; Tryptophan | 2012 |
The role of two Pseudomonas aeruginosa anthranilate synthases in tryptophan and quorum signal production.
Topics: Anthranilate Synthase; Bacterial Proteins; Gene Expression Regulation, Bacterial; ortho-Aminobenzoates; Phylogeny; Pseudomonas aeruginosa; Quinolones; Signal Transduction; Tryptophan | 2013 |
A novel muconic acid biosynthesis approach by shunting tryptophan biosynthesis via anthranilate.
Topics: Biosynthetic Pathways; Biotechnology; Catechol 1,2-Dioxygenase; Chromatography, High Pressure Liquid; Escherichia coli; Glutamate-Ammonia Ligase; Mixed Function Oxygenases; ortho-Aminobenzoates; Plasmids; Sorbic Acid; Tryptophan | 2013 |
A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Body Mass Index; Creatinine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Middle Aged; Motor Activity; Neopterin; Norway; ortho-Aminobenzoates; Reference Values; Smoking; Tryptophan; Xanthurenates | 2013 |
Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design.
Topics: Adult; Asthma; Biomarkers; Breath Tests; Bronchoalveolar Lavage Fluid; Case-Control Studies; Cytokines; Disease Progression; Eosinophil Cationic Protein; Eosinophils; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Nitric Oxide; ortho-Aminobenzoates; Peroxidase; Picornaviridae Infections; Prospective Studies; Quinolinic Acid; Rhinovirus; Tryptophan; Young Adult | 2013 |
An iterative, bimodular nonribosomal peptide synthetase that converts anthranilate and tryptophan into tetracyclic asperlicins.
Topics: Aspergillus; Benzodiazepinones; Biocatalysis; Cyclization; Holoenzymes; Models, Molecular; Oligopeptides; ortho-Aminobenzoates; Peptide Synthases; Protein Structure, Tertiary; Solubility; Stereoisomerism; Tryptophan | 2013 |
A mathematical model of tryptophan metabolism via the kynurenine pathway provides insights into the effects of vitamin B-6 deficiency, tryptophan loading, and induction of tryptophan 2,3-dioxygenase on tryptophan metabolites.
Topics: Animals; Brain; Contraceptives, Oral; Female; Humans; Hydrolases; Intestines; Kynurenic Acid; Kynurenine; Liver; Mice; Models, Theoretical; Muscles; ortho-Aminobenzoates; Rats; Transaminases; Tryptophan; Tryptophan Oxygenase; Vitamin B 6 Deficiency | 2013 |
A conserved suppressor mutation in a tryptophan auxotroph results in dysregulation of Pseudomonas quinolone signal synthesis.
Topics: Chorismic Acid; Gene Expression Regulation, Bacterial; Molecular Structure; Mutation; ortho-Aminobenzoates; Polymerase Chain Reaction; Pseudomonas aeruginosa; Quinolones; Tryptophan | 2014 |
A single-run liquid chromatography mass spectrometry method to quantify neuroactive kynurenine pathway metabolites in rat plasma.
Topics: Animals; Blood-Brain Barrier; Chromatography, High Pressure Liquid; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Plasma; Rats; Tryptophan | 2015 |
Large amounts of picolinic acid are lethal but small amounts increase the conversion of tryptophan-nicotinamide in rats.
Topics: Animals; Body Weight; Carboxy-Lyases; Dose-Response Relationship, Drug; Iron Chelating Agents; Kynurenic Acid; Liver; Male; Niacinamide; ortho-Aminobenzoates; Pentosyltransferases; Picolinic Acids; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Xanthurenates | 2014 |
Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Arginine; Biomarkers; Dietary Supplements; Female; Healthy Volunteers; Humans; Kynurenic Acid; Kynurenine; Life Style; Male; Methionine; ortho-Aminobenzoates; Pyridoxal Phosphate; Sex Factors; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Xanthurenates; Young Adult | 2015 |
Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease.
Topics: 3-Hydroxyanthranilic Acid; Aged; Animals; Biomarkers; Body Mass Index; Cholesterol; Coronary Artery Disease; Cross-Sectional Studies; Energy Intake; Fatty Acids, Omega-3; Female; Fishes; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Neopterin; Norway; Nutrition Assessment; ortho-Aminobenzoates; Seafood; Triglycerides; Tryptophan; Xanthurenates | 2017 |
Evaluation of the antioxidant properties of tryptophan and its metabolites in in vitro assay.
Topics: Anti-Inflammatory Agents; Antioxidants; Cell Line, Tumor; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Growth Inhibitors; Humans; Interferon-gamma; Interleukin-6; Kynurenine; Melatonin; Milk, Human; Neuroglia; ortho-Aminobenzoates; Oxygen Radical Absorbance Capacity; Quinolinic Acid; Recombinant Proteins; Tryptophan; Tumor Necrosis Factor-alpha; Xanthurenates | 2016 |
Burkholderia pseudomallei kynB plays a role in AQ production, biofilm formation, bacterial swarming and persistence.
Topics: Arylformamidase; Biofilms; Burkholderia pseudomallei; Gene Deletion; Locomotion; ortho-Aminobenzoates; Quinolones; Signal Transduction; Tryptophan; Virulence | 2016 |
TrpE feedback mutants reveal roadblocks and conduits toward increasing secondary metabolism in Aspergillus fumigatus.
Topics: Amino Acid Sequence; Amino Acids; Anthranilate Synthase; Aspergillus fumigatus; Escherichia coli; Feedback, Physiological; Fungal Proteins; Multigene Family; Mutation; ortho-Aminobenzoates; Peptide Synthases; Quinazolines; Secondary Metabolism; Tryptophan | 2016 |
Activity of the kynurenine pathway and its interplay with immunity in patients with pulmonary arterial hypertension.
Topics: Adult; Aged; Area Under Curve; Case-Control Studies; Disease Progression; Echocardiography, Doppler; Exercise Test; Female; Flow Cytometry; Humans; Hypertension, Pulmonary; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Prospective Studies; ROC Curve; T-Lymphocytes, Regulatory; Th17 Cells; Tryptophan | 2016 |
Altered serum levels of kynurenine metabolites in patients affected by cluster headache.
Topics: Adult; Cluster Headache; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan; Xanthurenates | 2015 |
Altered kynurenine pathway metabolites in serum of chronic migraine patients.
Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; Middle Aged; Migraine Disorders; ortho-Aminobenzoates; Quinolinic Acid; Tandem Mass Spectrometry; Tryptophan; Xanthurenates | 2015 |
Female Flinders Sensitive Line rats show estrous cycle-independent depression-like behavior and altered tryptophan metabolism.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Brain; Depressive Disorder; Disease Models, Animal; Estrous Cycle; Female; Kynurenine; Male; Motor Activity; ortho-Aminobenzoates; Quinolinic Acid; Rats; Resilience, Psychological; Sex Characteristics; Tryptophan | 2016 |
Tryptophan catabolism in Pseudomonas aeruginosa and potential for inter-kingdom relationship.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Host-Pathogen Interactions; Immunity, Innate; Kynurenic Acid; Kynurenine; Metabolic Networks and Pathways; Mice; Murinae; ortho-Aminobenzoates; Pseudomonas aeruginosa; Pseudomonas Infections; Transaminases; Tryptophan | 2016 |
Synthesis of Psychrophilin E.
Topics: Aspergillus; Indoles; Nitrogen; Nuclear Magnetic Resonance, Biomolecular; ortho-Aminobenzoates; Peptides, Cyclic; Spectrometry, Mass, Electrospray Ionization; Tryptophan | 2016 |
Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Female; Humans; Inflammation; Interleukin-10; Kynurenine; Linear Models; Male; Neopterin; ortho-Aminobenzoates; Pyridoxal Phosphate; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Young Adult | 2016 |
LC-MS/MS-based quantification of kynurenine metabolites, tryptophan, monoamines and neopterin in plasma, cerebrospinal fluid and brain.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Humans; Kynurenine; Mice, Inbred C57BL; Neopterin; ortho-Aminobenzoates; Quinolinic Acid; Signal Transduction; Tandem Mass Spectrometry; Tryptophan | 2016 |
Kynurenine pathway metabolism following prenatal KMO inhibition and in Mecp2
Topics: Animals; Autism Spectrum Disorder; Brain; Chromatography, Liquid; Female; Kynurenic Acid; Kynurenine; Methyl-CpG-Binding Protein 2; ortho-Aminobenzoates; Pregnancy; Rats, Wistar; Tandem Mass Spectrometry; Tryptophan | 2016 |
Distribution of the tryptophan pathway-derived defensive secondary metabolites gramine and benzoxazinones in Poaceae.
Topics: Alkaloids; Benzoxazines; Chromatography, Liquid; Indole Alkaloids; Metabolic Networks and Pathways; ortho-Aminobenzoates; Poaceae; Secondary Metabolism; Tandem Mass Spectrometry; Tryptophan | 2017 |
Increased breakdown of kynurenine towards its neurotoxic branch in bipolar disorder.
Topics: Adult; Bipolar Disorder; Brain; Case-Control Studies; Cognition; Depression; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Middle Aged; Multivariate Analysis; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan | 2017 |
Controversial alkoxyl and peroxyl radical scavenging activity of the tryptophan metabolite 3-hydroxy-anthranilic acid.
Topics: Alcohols; Amidines; Animals; Antioxidants; Female; Free Radical Scavengers; Free Radicals; Kinetics; Lipid Peroxidation; Mice; ortho-Aminobenzoates; Oxidation-Reduction; Peroxides; Rats; Tryptophan | 2017 |
Overproduction of L-tryptophan via simultaneous feed of glucose and anthranilic acid from recombinant Escherichia coli W3110: Kinetic modeling and process scale-up.
Topics: Bioreactors; Escherichia coli; Glucose; Kinetics; Metabolic Engineering; Models, Biological; ortho-Aminobenzoates; Recombinant Proteins; Tryptophan | 2018 |
Anti-biofilm effects of anthranilate on a broad range of bacteria.
Topics: Bacteria; Biofilms; Cyclic GMP; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Movement; ortho-Aminobenzoates; Tryptophan | 2017 |
Anthranilic acid, the new player in the ensemble of aromatic residue labeling precursor compounds.
Topics: Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; ortho-Aminobenzoates; Proteins; Tryptophan | 2017 |
Co-addition Strategy for Enhancement of Chaetominine from Submerged Fermentation of Aspergillus fumigatus CY018.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Alanine; Aspergillus fumigatus; Bioreactors; Fermentation; Humans; Indole Alkaloids; K562 Cells; ortho-Aminobenzoates; Shikimic Acid; Transcription, Genetic; Tryptophan | 2018 |
Alterations in the metabolism of tryptophan in patients with chronic hepatitis C six months after pegylated interferon-α 2a treatment.
Topics: Adult; Antiviral Agents; Depression; Depressive Disorder; Female; Hepatitis C; Hepatitis C, Chronic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Polyethylene Glycols; Recombinant Proteins; Tryptophan | 2018 |
Hypothesis kynurenic and quinolinic acids: The main players of the kynurenine pathway and opponents in inflammatory disease.
Topics: Animals; Anti-Inflammatory Agents; Humans; Immunosuppressive Agents; Inflammation; Kynurenic Acid; Kynurenine; Male; Models, Theoretical; ortho-Aminobenzoates; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Wistar; Tryptophan | 2018 |
Tryptophan and Kynurenine Metabolites: Are They Related to Depression?
Topics: Adult; Bipolar Disorder; Case-Control Studies; Depressive Disorder, Major; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; ortho-Aminobenzoates; Suicide, Attempted; Tryptophan; Xanthurenates | 2019 |
Noninvasive Serum Metabolomic Profiling Reveals Elevated Kynurenine Pathway's Metabolites in Humans with Prostate Cancer.
Topics: Aged; Biomarkers, Tumor; Humans; Kynurenine; Male; Metabolome; Metabolomics; Middle Aged; ortho-Aminobenzoates; Principal Component Analysis; Prostate-Specific Antigen; Prostatic Neoplasms; Reproducibility of Results; Tryptophan | 2019 |
Serum xanthurenic acid levels: Reduced in subjects at ultra high risk for psychosis.
Topics: Adolescent; Adult; Disease Progression; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Prodromal Symptoms; Psychotic Disorders; Quinolinic Acid; Risk; Schizophrenia; Tryptophan; Xanthurenates; Young Adult | 2019 |
Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy.
Topics: 3-Hydroxyanthranilic Acid; Affect; Case-Control Studies; Electroconvulsive Therapy; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Picolinic Acids; Quinolinic Acid; Tryptophan; Xanthurenates | 2020 |
Host and Microbial Tryptophan Metabolic Profiling in Multiple Sclerosis.
Topics: Adult; Biomarkers; Female; Gastrointestinal Microbiome; Humans; Italy; Kynurenine; Male; Metabolomics; Multiple Sclerosis; ortho-Aminobenzoates; Prospective Studies; Recurrence; Serotonin; Tryptophan; Young Adult | 2020 |
Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice.
Topics: Animals; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Liver; Male; Metabolic Networks and Pathways; Metabolomics; Mice, Knockout; ortho-Aminobenzoates; Serotonin; Spleen; Tryptophan; Tryptophan Oxygenase | 2020 |
The role of anthranilic acid in the increase of depressive symptoms and major depressive disorder during treatment for hepatitis C with pegylated interferon-α2a and oral ribavirin.
Topics: Adult; Antiviral Agents; Cross-Sectional Studies; Depression; Depressive Disorder, Major; Female; Hepatitis C, Chronic; Humans; Immunologic Factors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Kynurenic Acid; Kynurenine; Longitudinal Studies; Male; Middle Aged; ortho-Aminobenzoates; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Tryptophan | 2021 |
Kynurenine pathway activation and deviation to anthranilic and kynurenic acid in fibrosing chronic graft-versus-host disease.
Topics: Adolescent; Adult; Aged; Chemokine CXCL9; Female; Fibrosis; Gene Expression Regulation; Graft vs Host Disease; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interleukin-18; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Leukemia; Lymphoma; Male; Metabolic Networks and Pathways; Middle Aged; ortho-Aminobenzoates; Retrospective Studies; Riboflavin; Severity of Illness Index; Signal Transduction; Stem Cell Transplantation; Transplantation, Homologous; Tryptophan; Vitamin B 6 | 2021 |
The Cytokines CXCL10 and CCL2 and the Kynurenine Metabolite Anthranilic Acid Accurately Predict Patients at Risk of Developing Dengue With Warning Signs.
Topics: Chemokine CCL2; Chemokine CXCL10; Cytokines; Humans; Interferon-gamma; Interleukin-18; Kynurenine; Severe Dengue; Tryptophan | 2022 |
Anthranilic Acid Accumulation in Saccharomyces cerevisiae Induced by Expression of a Nonribosomal Peptide Synthetase Gene from Paecilomyces cinnamomeus BCC 9616.
Topics: ortho-Aminobenzoates; Peptide Synthases; Saccharomyces cerevisiae; Tryptophan | 2022 |
Serum tryptophan metabolites are associated with erosive hand osteoarthritis and pain: results from the DIGICOD cohort.
Topics: Cross-Sectional Studies; Humans; Kynurenine; Osteoarthritis; Pain; Serotonin; Tryptophan | 2023 |
Liquid chromatography-tandem mass spectrometry based simultaneous quantification of tryptophan, serotonin and kynurenine pathway metabolites in tissues and cell culture systems.
Topics: Animals; Chromatography, Liquid; Dioxygenases; Kynurenine; Mice; Niacin; Reproducibility of Results; Serotonin; Tandem Mass Spectrometry; Tryptophan | 2023 |