tryptophan and alpha-synuclein

tryptophan has been researched along with alpha-synuclein in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (33.33)29.6817
2010's13 (54.17)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Andrekopoulos, C; Crow, J; Joseph, J; Kalyanaraman, B; Zhang, H1
Bodner, N; Edridge, S; Fink, AL; Hong, DP; Kaylor, J; Yamin, G1
Bodner, N; Dusa, A; Edridge, S; Fink, AL; Hong, DP; Kaylor, J1
Gray, HB; Harkins, SB; Lee, JC; Winkler, GR1
Gray, HB; Kozak, JJ; Lai, BT; Lee, JC; Winkler, JR1
Adame, A; Crews, L; Dallapiccola, B; Marongiu, R; Masliah, E; Patrick, C; Spencer, B; Trejo, M; Valente, EM1
Jackson, MS; Lee, JC1
Claessens, MM; Subramaniam, V; van Leijenhorst-Groener, KA; van Rooijen, BD1
Lee, JC; Lucas, HR1
Lee, JC; Pfefferkorn, CM2
Adalist, YH; Gazit, E; Scherzer-Attali, R; Segal, D; Shaltiel-Karyo, R1
Cernocká, H; Kurzątkowska, K; Ostatná, V; Paleček, E1
Engelborghs, Y; Kluba, M; Meuvis, J; Schreurs, S1
Buijsman, RC; Dettmer, K; Farina, F; Kema, IP; Krijnen, J; Melki, R; Michels, H; Neri, C; Nollen, EA; Oefner, PJ; Ruiz Silva, M; Seinstra, RI; Thijssen, KL; van der Goot, AT; Vázquez-Manrique, RP; Zhu, W1
Amoussouvi, A; Haralampiev, I; Herrmann, A; Stöckl, M; Wietek, J1
de Messieres, M; Jiang, Z; Lee, JC1
Shvadchak, VV; Subramaniam, V1
Cai, Z; Chen, LL; Chua, KK; Li, M; Liu, LF; Luan, H; Meng, N; Mok, VC; Song, JX; Tang, Z; Xie, LX1
Barros, M; Curtis, JE; Gruschus, JM; Heinrich, F; Jiang, Z; Lee, JC; Pfefferkorn, CM; Sidransky, E; Yap, TL1
DAS, D; Mukhopadhyay, S1
Acosta, D; Das, T; Eliezer, D1
Abraham, JN; Srikanth, P; Sunitha, AK; Sunny, LP; Tembulkar, N1
Dai, L; Du, Z; Fang, Y; Jiang, H; Li, F; Li, H; Liu, C; Liu, Z; Meng, L; Tian, Y; Wang, Z; Xiong, M; Yan, Z; Yu, T; Yuan, X; Zhang, J; Zhang, Z1

Reviews

1 review(s) available for tryptophan and alpha-synuclein

ArticleYear
The carbonate radical anion-induced covalent aggregation of human copper, zinc superoxide dismutase, and alpha-synuclein: intermediacy of tryptophan- and tyrosine-derived oxidation products.
    Free radical biology & medicine, 2004, Jun-01, Volume: 36, Issue:11

    Topics: alpha-Synuclein; Carbonates; Free Radicals; Humans; Monophenol Monooxygenase; Nerve Tissue Proteins; Oxidation-Reduction; Superoxide Dismutase; Synucleins; Tryptophan

2004

Other Studies

23 other study(ies) available for tryptophan and alpha-synuclein

ArticleYear
Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein.
    Journal of molecular biology, 2005, Oct-21, Volume: 353, Issue:2

    Topics: alpha-Synuclein; Anilino Naphthalenesulfonates; Benzothiazoles; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Parkinson Disease; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Synucleins; Thiazoles; Tryptophan; Tyrosine

2005
Characterization of oligomers during alpha-synuclein aggregation using intrinsic tryptophan fluorescence.
    Biochemistry, 2006, Feb-28, Volume: 45, Issue:8

    Topics: Acrylamide; alpha-Synuclein; Amino Acid Substitution; Amyloid; Anilino Naphthalenesulfonates; Fluorescence; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; Protein Structure, Secondary; Solvents; Time Factors; Tryptophan; Tyrosine

2006
Alpha-synuclein structures probed by 5-fluorotryptophan fluorescence and 19F NMR spectroscopy.
    The journal of physical chemistry. B, 2006, Apr-06, Volume: 110, Issue:13

    Topics: alpha-Synuclein; Fluorescence; Fluorine; Isotopes; Magnetic Resonance Spectroscopy; Tryptophan

2006
Alpha-synuclein tertiary contact dynamics.
    The journal of physical chemistry. B, 2007, Mar-01, Volume: 111, Issue:8

    Topics: alpha-Synuclein; Amino Acid Sequence; Electron Transport; Molecular Sequence Data; Protein Conformation; Tryptophan; Tyrosine

2007
Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson's disease by disturbing calcium flux.
    Journal of neurochemistry, 2009, Volume: 108, Issue:6

    Topics: Adenosine Triphosphate; Alanine; alpha-Synuclein; Analysis of Variance; Animals; Calcium; Cell Line, Tumor; Cobalt; Dose-Response Relationship, Drug; Flufenamic Acid; Gene Expression Regulation; Green Fluorescent Proteins; Microscopy, Electron, Transmission; Microtubule-Associated Proteins; Mitochondria; Mutation; Neuroblastoma; Neurons; Protein Kinases; Rats; Threonine; Transfection; Tryptophan

2009
Identification of the minimal copper(II)-binding alpha-synuclein sequence.
    Inorganic chemistry, 2009, Oct-05, Volume: 48, Issue:19

    Topics: alpha-Synuclein; Amino Acid Sequence; Binding Sites; Catalysis; Copper; Electron Spin Resonance Spectroscopy; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Peptides; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Tryptophan

2009
Tryptophan fluorescence reveals structural features of alpha-synuclein oligomers.
    Journal of molecular biology, 2009, Dec-18, Volume: 394, Issue:5

    Topics: alpha-Synuclein; Amino Acid Substitution; Fluorescence; Lipid Metabolism; Mutagenesis, Site-Directed; Protein Binding; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrum Analysis; Tryptophan

2009
Effect of dioxygen on copper(II) binding to alpha-synuclein.
    Journal of inorganic biochemistry, 2010, Volume: 104, Issue:3

    Topics: alpha-Synuclein; Amino Acid Sequence; Binding Sites; Circular Dichroism; Copper; Methionine; Molecular Conformation; Molecular Sequence Data; Oxidation-Reduction; Oxygen; Peptides; Protein Binding; Tryptophan

2010
Tryptophan probes at the alpha-synuclein and membrane interface.
    The journal of physical chemistry. B, 2010, Apr-08, Volume: 114, Issue:13

    Topics: alpha-Synuclein; Circular Dichroism; Lipid Bilayers; Protein Binding; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan

2010
Generic inhibition of amyloidogenic proteins by two naphthoquinone-tryptophan hybrid molecules.
    Proteins, 2012, Volume: 80, Issue:8

    Topics: alpha-Synuclein; Alzheimer Disease; Amyloidogenic Proteins; Calcitonin; Humans; Insulin; Islet Amyloid Polypeptide; Muramidase; Naphthoquinones; Tryptophan

2012
Native and denatured forms of proteins can be discriminated at edge plane carbon electrodes.
    Analytica chimica acta, 2012, Jul-20, Volume: 735

    Topics: alpha-Synuclein; Animals; Cattle; Chickens; Electrochemical Techniques; Electrodes; Fructose-Bisphosphate Aldolase; Graphite; Humans; Protein Denaturation; Proteins; Serum Albumin; Tryptophan; Tyrosine; Urea

2012
5-fluoro-D,L-tryptophan as a dual NMR and fluorescent probe of α-synuclein.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 895

    Topics: alpha-Synuclein; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fluorescent Dyes; Humans; Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Spectrometry, Mass, Electrospray Ionization; Tryptophan

2012
Fluorescence lifetime measurements of intrinsically unstructured proteins: application to α-synuclein.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 895

    Topics: Algorithms; alpha-Synuclein; Amino Acid Substitution; Anisotropy; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Naphthalenesulfonates; Protein Conformation; Spectrometry, Fluorescence; Staining and Labeling; Tryptophan; Tyrosine

2012
Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Sep-11, Volume: 109, Issue:37

    Topics: Aging; alpha-Synuclein; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Chromatography, Liquid; Computational Biology; DNA Primers; Fertility; Homeostasis; Immunoblotting; Longevity; Peptides; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tandem Mass Spectrometry; Tryptophan; Tryptophan Oxygenase

2012
Membrane bound α-synuclein is fully embedded in the lipid bilayer while segments with higher flexibility remain.
    FEBS letters, 2013, Aug-19, Volume: 587, Issue:16

    Topics: Acrylamide; alpha-Synuclein; Amino Acid Sequence; Cell Membrane; Humans; Lipid Bilayers; Lipids; Micelles; Molecular Sequence Data; Parkinson Disease; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Tryptophan

2013
Membrane remodeling by α-synuclein and effects on amyloid formation.
    Journal of the American Chemical Society, 2013, Oct-30, Volume: 135, Issue:43

    Topics: Adenosine; alpha-Synuclein; Amyloid; Cholesterol; Circular Dichroism; Glycerophospholipids; Indicators and Reagents; Lipid Bilayers; Lipids; Membranes, Artificial; Microscopy, Electron, Transmission; Microtubules; Neutrons; Phosphatidylcholines; Spectrophotometry, Ultraviolet; Tryptophan

2013
A four-amino acid linker between repeats in the α-synuclein sequence is important for fibril formation.
    Biochemistry, 2014, Jan-21, Volume: 53, Issue:2

    Topics: alpha-Synuclein; Amino Acid Sequence; Amino Acids; Amyloid; Fluorescence; Humans; Models, Molecular; Mutation; Protein Conformation; Tryptophan

2014
LC-MS-based urinary metabolite signatures in idiopathic Parkinson's disease.
    Journal of proteome research, 2015, Jan-02, Volume: 14, Issue:1

    Topics: alpha-Synuclein; Animals; Biomarkers; Chromatography, Liquid; Drosophila melanogaster; Fatty Acids; Histidine; Humans; Kynurenine; Mass Spectrometry; Metabolomics; Nucleotides; Parkinson Disease; Phenotype; Phenylalanine; Steroids; Tryptophan; Tyrosine

2015
Structural features of membrane-bound glucocerebrosidase and α-synuclein probed by neutron reflectometry and fluorescence spectroscopy.
    The Journal of biological chemistry, 2015, Jan-09, Volume: 290, Issue:2

    Topics: alpha-Synuclein; Gaucher Disease; Glucosylceramidase; Humans; Lipid Bilayers; Mutation; Neutron Diffraction; Parkinson Disease; Protein Binding; Spectrometry, Fluorescence; Surface Plasmon Resonance; Tryptophan

2015
Studying backbone torsional dynamics of intrinsically disordered proteins using fluorescence depolarization kinetics.
    Journal of biosciences, 2018, Volume: 43, Issue:3

    Topics: alpha-Synuclein; Fluorescence Polarization; Humans; Intrinsically Disordered Proteins; Kinetics; Molecular Dynamics Simulation; Protein Aggregates; Protein Conformation; Solutions; Spectrometry, Fluorescence; Time Factors; Torsion, Mechanical; Tryptophan

2018
Probing IDP Interactions with Membranes by Fluorescence Spectroscopy.
    Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2141

    Topics: 2-Naphthylamine; alpha-Synuclein; Cell Membrane; Darkness; Fourier Analysis; Intrinsically Disordered Proteins; Kinetics; Light; Membrane Lipids; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Recombinant Proteins; Spectrometry, Fluorescence; tau Proteins; Tryptophan; Unilamellar Liposomes

2020
Tryptophan-cardanol fluorescent nanoparticles inhibit α-synuclein aggregation and disrupt amyloid fibrils.
    Journal of peptide science : an official publication of the European Peptide Society, 2022, Volume: 28, Issue:4

    Topics: alpha-Synuclein; Amyloid; Nanoparticles; Phenols; Tryptophan

2022
Exposure to the environmentally toxic pesticide maneb induces Parkinson's disease-like neurotoxicity in mice: A combined proteomic and metabolomic analysis.
    Chemosphere, 2022, Volume: 308, Issue:Pt 2

    Topics: alpha-Synuclein; Animals; Environmental Pollutants; Fungicides, Industrial; Humans; Maneb; Metabolomics; Mice; Neuroblastoma; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Pesticides; Phenylalanine; Proteomics; Tryptophan

2022