tryptophan has been researched along with 5-methoxytryptophan in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (27.91) | 18.7374 |
| 1990's | 3 (6.98) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 18 (41.86) | 24.3611 |
| 2020's | 10 (23.26) | 2.80 |
| Authors | Studies |
|---|---|
| Audhya, TK; Dombrowski, TA; Fox, L; McNulty, JA; Prechel, MM; Simmons, WH; Taylor, D | 1 |
| Airaksinen, MM; Leino, M | 1 |
| Morton, DJ | 2 |
| Balemans, MG; de Koning, J; Ebels, I; van Benthem, J | 1 |
| Balemans, MG; Ebels, I; Mans, DR; van Benthem, J | 1 |
| Balemans, MG; de Reuver, GF; Pévet, P | 1 |
| Haldar-Misra, C; Pévet, P | 1 |
| Balemans, MG; de Moreé, A; Ebels, I; Hendriks, HG; van Berlo, M | 1 |
| Balemans, MG; Flight, WF; Mans, D | 1 |
| Balemans, MG; Bary, FA; Legerstee, WC; Van Benthem, J | 1 |
| Haldar-Misra, C; Ocal, T; Pévet, P | 1 |
| Boxer, SG; Pierce, DW | 1 |
| Brammer, GL | 1 |
| Honda, N; Komeiji, Y; Uebayasi, M; Yamato, I | 1 |
| Chen, HL; Cheng, HH; Flaberg, E; Guvén, H; Klein, G; Kuo, CC; Lin, WC; Szekely, L; Tsai, KK; Wang, KH; Wu, KK; Yan, JL | 1 |
| Chan, HL; Chou, HC | 1 |
| Chang, TC; Cheng, HH; Chu, LY; Kuo, CC; Wang, KH; Wu, KK | 1 |
| Hang, W; Huang, Q; Liu, L; Martin, FL; Mu, X; Shen, H; Tian, M; Xia, Y; Zhang, J | 1 |
| Chang, CW; Chou, HC; Wang, SH | 1 |
| Cheng, HH; Chu, LY; Kuo, CC; Wang, YF; Wu, KK | 1 |
| Chen, HL; Cheng, HH; Chiang, LY; Chu, LY; Kuo, CC; Wu, KK | 1 |
| Chen, CH; Ho, HH; Ho, YC; Hsu, YJ; Kuo, CC; Lee, GL; Lin, WS; Lin, WY; Su, CH; Wu, KK; Wu, ML; Yet, SF | 1 |
| Hsu, YJ; Kuo, CC; Lee, GL; Wang, YF; Wu, HF; Wu, JY; Wu, KK; Yang, YS; Yet, SF | 1 |
| Chen, YH; Chou, CH; Ho, YL; Huang, CC; Hung, CS; Kuo, CC; Lee, CM; Lin, YH; Liu, LD; Wu, KK; Yeh, JF | 1 |
| Huang, WL; Liu, XW; Yang, CJ; Yang, J; Yang, Y; Zeng, P | 1 |
| Kuo, CC; Lin, YH; Wu, KK | 1 |
| Chang, TC; Hsu, MF; Shih, CY; Wu, KK | 1 |
| Anderson, GM; Eighmie, JT | 1 |
| Anuforo, Ó; Bergmann, A; Halldórsson, H; Halldórsson, S; Henriksen, HH; Johansson, PI; McGarrity, S; Palsson, S; Rolfsson, Ó | 1 |
| Chang, TC; Chen, HL; Cheng, HH; Huang, SK; Kuo, CC; Wu, KK; Yuan, CY | 1 |
| Huang, JL; Kuo, CC; Kuo, ML; Lin, TC; Wu, CY; Yeh, KW | 1 |
| Argyopoulos, CP; Bayliss, GP; Cao, G; Chen, DQ; Chen, H; Chen, L; Cheng, XH; Guo, Y; Kang, H; Li, XR; Liu, D; Ma, SX; Mao, JR; Meng, MX; Samuels, DC; Shang, YQ; Su, W; Vaziri, ND; Wang, M; Ye, F; Yu, H; Yu, XY; Zhang, L; Zhang, Y; Zhao, J; Zhao, S; Zhao, YY; Zhuang, S | 1 |
| Chen, CH; Ho, HH; Ho, YC; Hsu, YJ; Jiang, WC; Kuo, CC; Lee, GL; Lee, JK; Liang, LY; Wu, KK; Yet, SF | 1 |
| Kuo, CC; Lee, CM; Liou, JY; Wu, KK; Yet, SF | 1 |
| Chen, H; Fang, L; Kong, R; Que, J | 1 |
| Chen, H; Fang, L; Hong, X; Jiang, F; Kong, R; Li, Y; Qian, Z | 1 |
| Chen, L; Lin, YH; Liu, M; Tang, SG; Tong, M; Zheng, Q; Zhu, YM | 1 |
| Wu, KK | 1 |
| Hsu, WT; Jui, HY; Kuo, CC; Lee, CM; Tseng, YH; Wu, KK | 1 |
| Cho, JY; Cowling, RT | 1 |
| Kuo, CC; Lee, GL; Liao, TL; Wu, JY; Wu, KK | 1 |
| He, S; Li, S; Li, X; Li, Y; Ma, Y; Ma, Z; Shi, J; Wang, Z; Wu, X; Yu, J | 1 |
3 review(s) available for tryptophan and 5-methoxytryptophan
| Article | Year |
|---|---|
Methoxyindoles of the retina.
Topics: 5-Methoxytryptamine; Animals; Carbolines; Circadian Rhythm; Humans; Hydroxyindoleacetic Acid; Indoles; Melatonin; Neurotransmitter Agents; Photic Stimulation; Pineal Gland; Rabbits; Retina; Serotonin; Tryptophan | 1985 |
5-methoxytryptophan: an arsenal against vascular injury and inflammation.
Topics: Animals; Anti-Inflammatory Agents; Humans; Inflammation; Mice; Tryptophan; Vascular System Injuries | 2020 |
Cytoguardin: A Tryptophan Metabolite against Cancer Growth and Metastasis.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Fibroblasts; Humans; Liver Neoplasms; Matrix Metalloproteinases; Mice; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Serotonin; Tryptophan | 2021 |
40 other study(ies) available for tryptophan and 5-methoxytryptophan
| Article | Year |
|---|---|
Pineal ultrastructure and indole profiles spanning the summer rise in arginine vasotocin immunoactivity.
Topics: 5-Hydroxytryptophan; Animals; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Hydroxytryptophol; Indoles; Male; Microscopy, Electron; Pineal Gland; Radioimmunoassay; Rats; Rats, Inbred Strains; Seasons; Serotonin; Tryptophan; Vasotocin | 1985 |
Effect of methoxyindole administration on plasma cation levels in the rat.
Topics: 5-Methoxytryptamine; Animals; Cations; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Hydroxyindoleacetic Acid; Indoles; Magnesium; Melatonin; Rats; Rats, Inbred Strains; Tryptophan; Zinc | 1989 |
The effect of different photoperiods on the methylating capacity of the pineal gland of adult, male golden hamsters, with special reference to 5-methoxyindoles.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Follicle Stimulating Hormone; Indoles; Light; Luteinizing Hormone; Male; Melatonin; Mesocricetus; Periodicity; Pineal Gland; Testis; Tryptophan | 1986 |
Production of methoxyindoles in vitro from methoxytryptophan by rat pineal gland.
Topics: Animals; Chemical Phenomena; Chemistry; Indoles; Male; Organ Culture Techniques; Pineal Gland; Rats; Rats, Inbred Strains; Tryptophan | 1987 |
Rhythmic synthesis of various 5-methoxyindoles in the pineal gland of male adult golden hamsters, kept under the same artificial conditions throughout the year.
Topics: 5-Hydroxytryptophan; 5-Methoxytryptamine; Animals; Cricetinae; Indoles; Male; Melatonin; Mesocricetus; Pineal Gland; Seasons; Tryptophan | 1985 |
The pineal gland of the mole (Talpa europaea L.). VII. Activity of hydroxyindole-O-methyltransferase (HIOMT) in the formation of 5-methoxytryptophan, 5-methoxytryptamine, 5-methoxyindole-3-acetic acid, 5-methoxytryptophol and melantonin in the eyes and th
Topics: 5-Methoxytryptamine; Acetylserotonin O-Methyltransferase; Aging; Animals; Eulipotyphla; Eye; Female; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Methyltransferases; Moles; Organ Specificity; Pineal Gland; Sex Factors; Sexual Maturation; Tryptamines; Tryptophan | 1981 |
The influence of different 5-methoxyindoles on the process of protein/peptide secretion characterized by the formation of granular vesicles in the mouse pineal gland. An in vitro study.
Topics: 5-Methoxytryptamine; Animals; Cells, Cultured; Cytoplasmic Granules; Hydroxyindoleacetic Acid; Indoles; Male; Melatonin; Mice; Pineal Gland; Proteins; Tryptophan | 1983 |
The influence of some pteridines on pineal 5-methoxyindole synthesis in male Wistar rats periodically exposed to either white or green light.
Topics: 5-Methoxytryptamine; Animals; Biopterins; Hydroxyindoleacetic Acid; Indoles; Light; Male; Melanins; Neopterin; Pineal Gland; Pteridines; Pterins; Rats; Rats, Inbred Strains; Tryptophan | 1983 |
Methoxyindole synthesis in the retina of the frog (Rana esculenta) during a diurnal period.
Topics: 5-Methoxytryptamine; Animals; Circadian Rhythm; Hydroxyindoleacetic Acid; Indoles; Melatonin; Pigment Epithelium of Eye; Rana esculenta; Retina; Tryptophan | 1983 |
Seasonal variations in HIOMT activity during the night in the pineal gland of 21 day old male Wistar rats.
Topics: 5-Methoxytryptamine; Acetylserotonin O-Methyltransferase; Animals; Circadian Rhythm; Indoles; Isoenzymes; Male; Melatonin; Methyltransferases; Pineal Gland; Rats; Seasons; Tryptophan | 1980 |
Effect of 5-methoxytryptophan and 5-methoxytryptamine on the reproductive system of the male golden hamster.
Topics: 5-Methoxytryptamine; Animals; Cricetinae; Male; Mesocricetus; Organ Size; Reproduction; Testis; Tryptamines; Tryptophan | 1981 |
Stark effect spectroscopy of tryptophan.
Topics: Biophysical Phenomena; Biophysics; Electrochemistry; Fluorescence Polarization; Melitten; Models, Chemical; Photochemistry; Solvents; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan | 1995 |
Duodenum is not a consistent source of melatonin in rats.
Topics: 5-Hydroxytryptophan; Animals; Chromatography; Duodenum; In Vitro Techniques; Male; Melatonin; Pineal Gland; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin; Spectrometry, Fluorescence; Tryptophan | 1994 |
Computational design of a substrate specificity mutant of a protein.
Topics: Bacterial Proteins; Models, Chemical; Mutagenesis; Repressor Proteins; Substrate Specificity; Thermodynamics; Tryptophan | 1996 |
Control of cyclooxygenase-2 expression and tumorigenesis by endogenous 5-methoxytryptophan.
Topics: Acetylserotonin O-Methyltransferase; Animals; Biocatalysis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Fibroblasts; Humans; Metabolic Networks and Pathways; Metabolomics; Mice; Neoplasm Metastasis; Solubility; Subcellular Fractions; Tryptophan; Tryptophan Hydroxylase; Xenograft Model Antitumor Assays | 2012 |
5-Methoxytryptophan-dependent protection of cardiomyocytes from heart ischemia reperfusion injury.
Topics: Animals; Cell Death; Cell Line; Cell Survival; Cytoprotection; Endoplasmic Reticulum Stress; Hydrogen Peroxide; Myocytes, Cardiac; Proteomics; Rats; Reperfusion Injury; Transcriptome; Tryptophan | 2014 |
Quiescent and proliferative fibroblasts exhibit differential p300 HAT activation through control of 5-methoxytryptophan production.
Topics: Anti-Inflammatory Agents; Cell Differentiation; Cell Proliferation; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Fibroblasts; Gene Silencing; Humans; Immunoenzyme Techniques; Inflammation; Mass Spectrometry; p300-CBP Transcription Factors; Promoter Regions, Genetic; RNA, Small Interfering; Sepharose; Streptavidin; Tryptophan | 2014 |
Metabolomic analysis reveals a unique urinary pattern in normozoospermic infertile men.
Topics: Adult; Aspartic Acid; Biomarkers; Carnitine; Humans; Infertility, Male; Leukotriene E4; Male; Metabolome; Metabolomics; Ribonucleosides; ROC Curve; Tryptophan; Xanthines; Young Adult | 2014 |
5-Methoxytryptophan-dependent inhibition of oral squamous cell carcinoma metastasis.
Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Female; Humans; Mice; Mice, Nude; Mouth Neoplasms; Neoplasm Invasiveness; Proteome; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan; Two-Dimensional Difference Gel Electrophoresis | 2015 |
Endothelium-Derived 5-Methoxytryptophan Protects Endothelial Barrier Function by Blocking p38 MAPK Activation.
Topics: Animals; Antigens, CD; Cadherins; Capillary Permeability; Cells, Cultured; Culture Media, Conditioned; Down-Regulation; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Protective Agents; Tryptophan | 2016 |
Inhibition of cancer cell epithelial mesenchymal transition by normal fibroblasts via production of 5-methoxytryptophan.
Topics: A549 Cells; Animals; Cadherins; Cell Line; Coculture Techniques; Epithelial-Mesenchymal Transition; Fibroblasts; Humans; Lung Neoplasms; Mice, SCID; NF-kappa B; p38 Mitogen-Activated Protein Kinases; RNA Interference; Transforming Growth Factor beta1; Tryptophan; Tryptophan Hydroxylase; Vimentin; Xenograft Model Antitumor Assays | 2016 |
A Novel Protective Function of 5-Methoxytryptophan in Vascular Injury.
Topics: Aged; Animals; Arteries; Cells, Cultured; Coronary Artery Disease; Disease Models, Animal; Female; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Male; MAP Kinase Signaling System; Mice; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neointima; Tryptophan; Vascular System Injuries | 2016 |
Endothelium-Derived 5-Methoxytryptophan Is a Circulating Anti-Inflammatory Molecule That Blocks Systemic Inflammation.
Topics: Aged; Aged, 80 and over; Animals; Anti-Inflammatory Agents; Endothelium, Vascular; Endotoxemia; Female; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Middle Aged; Tryptophan | 2016 |
5-methoxytryptophan is a potential marker for post-myocardial infarction heart failure - a preliminary approach to clinical utility.
Topics: Aged; Biomarkers; Echocardiography; Female; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Prognosis; Prospective Studies; ROC Curve; ST Elevation Myocardial Infarction; Time Factors; Tryptophan; Ventricular Remodeling | 2016 |
5-Methoxytryptophan: A promising early marker for predicting post-myocardial infarction heart failure.
Topics: Heart Failure; Humans; Myocardial Infarction; Tryptophan | 2017 |
Reply to letter: "5-Methoxytryptophan: A promising early marker for predicting post-myocardial infarction heart failure".
Topics: Heart Failure; Humans; Myocardial Infarction; Tryptophan | 2017 |
5-methoxytryptophan protects MSCs from stress induced premature senescence by upregulating FoxO3a and mTOR.
Topics: Adipogenesis; Cell Differentiation; Cell Proliferation; Cellular Senescence; Forkhead Box Protein O3; Glucose; Humans; Hydrogen Peroxide; Mesenchymal Stem Cells; Osteogenesis; Protective Agents; Signal Transduction; Stress, Physiological; TOR Serine-Threonine Kinases; Tryptophan | 2017 |
The determination of 5-methoxytryptophan in human plasma.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Humans; Limit of Detection; Male; Middle Aged; Reproducibility of Results; Solid Phase Extraction; Tryptophan; Young Adult | 2018 |
Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification.
Topics: Biomarkers; Cell Line; Chromatography, High Pressure Liquid; Endothelial Cells; Fatty Acids; gamma-Aminobutyric Acid; Glycocalyx; Human Umbilical Vein Endothelial Cells; Humans; Interferon-gamma; Kynurenine; Lipopolysaccharides; Lysophospholipids; Metabolome; Models, Biological; Nitric Oxide; Permeability; Polysaccharides; Prostaglandin D2; Sepsis; Sphingosine; Survival Analysis; Tryptophan | 2018 |
Restoration of hydroxyindole
Topics: Acetylserotonin O-Methyltransferase; Animals; Apoptosis; Cell Proliferation; Humans; Lung Neoplasms; Male; Mice; Mice, SCID; Serotonin; Tryptophan; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2018 |
The role of 5-methoxytryptophan in pediatric-onset lupus nephritis: A retrospective cohort study.
Topics: Adolescent; Antibodies; Biopsy; Child; Female; Humans; Immunosuppressive Agents; Lupus Nephritis; Male; Prognosis; Retrospective Studies; Tryptophan | 2020 |
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
Topics: Acetylcarnitine; Animals; Canavanine; Carnitine; Case-Control Studies; Disease Models, Animal; Disease Progression; Fibrosis; Gene Knock-In Techniques; Gene Knockdown Techniques; Humans; I-kappa B Proteins; Inflammation; Kelch-Like ECH-Associated Protein 1; Kidney; Metabolomics; Mice; NF-E2-Related Factor 2; NF-kappa B; Renal Insufficiency, Chronic; Severity of Illness Index; Signal Transduction; Taurine; Tryptophan; Tryptophan Hydroxylase; Ureteral Obstruction | 2019 |
Tryptophan metabolite 5-methoxytryptophan ameliorates arterial denudation-induced intimal hyperplasia via opposing effects on vascular endothelial and smooth muscle cells.
Topics: Animals; Cell Movement; Cell Proliferation; Coronary Restenosis; Endothelium, Vascular; Mice; Myocytes, Smooth Muscle; Protective Factors; Tryptophan; Vascular Endothelial Growth Factor A | 2019 |
Endogenous tryptophan metabolite 5-Methoxytryptophan inhibits pulmonary fibrosis by downregulating the TGF-β/SMAD3 and PI3K/AKT signaling pathway.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Cell Differentiation; Extracellular Matrix; Gene Expression Regulation; Humans; Lung; Male; Mice; Mice, Inbred C57BL; Myofibroblasts; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pulmonary Fibrosis; Smad3 Protein; Transforming Growth Factor beta; Tryptophan | 2020 |
Treatment with 5-methoxytryptophan attenuates microglia-induced neuroinflammation in spinal cord trauma.
Topics: Animals; Cell Line; Female; Humans; Inflammation; Mice; Mice, Inbred C57BL; Microglia; Spinal Cord Injuries; Tryptophan | 2020 |
5-methoxytryptophan alleviates liver fibrosis by modulating FOXO3a/miR-21/ATG5 signaling pathway mediated autophagy.
Topics: Animals; Autophagy; Autophagy-Related Protein 5; Carbon Tetrachloride; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Forkhead Box Protein O3; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Male; MicroRNAs; Rats; Rats, Sprague-Dawley; Signal Transduction; Tryptophan | 2021 |
5-Methoxytryptophan attenuates postinfarct cardiac injury by controlling oxidative stress and immune activation.
Topics: Animals; Apoptosis; Cell Line, Transformed; Disease Models, Animal; Female; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Immunity; Myocardial Infarction; Myocarditis; Myocardium; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Treatment Outcome; Tryptophan; Ventricular Function, Left; Ventricular Remodeling | 2021 |
5-Methoxytryptophan: A game changer in the management of post-myocardial infarction?
Topics: Animals; Anti-Inflammatory Agents; Cardiotonic Agents; Disease Models, Animal; Humans; Myocardial Infarction; Myocardial Revascularization; Treatment Outcome; Tryptophan | 2021 |
Restoration of 5-methoxytryptophan protects against atherosclerotic chondrogenesis and calcification in ApoE
Topics: Animals; Atherosclerosis; Calcinosis; Chondrogenesis; Diet, High-Fat; Mice; Tryptophan | 2021 |
5-Methoxytryptophan ameliorates endotoxin-induced acute lung injury in vivo and in vitro by inhibiting NLRP3 inflammasome-mediated pyroptosis through the Nrf2/HO-1 signaling pathway.
Topics: Acute Lung Injury; Animals; Endotoxins; Inflammasomes; Lipopolysaccharides; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Signal Transduction; Tryptophan | 2023 |