tryptophan has been researched along with 3-hydroxyanthranilic acid in 122 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (39.34) | 18.7374 |
| 1990's | 19 (15.57) | 18.2507 |
| 2000's | 20 (16.39) | 29.6817 |
| 2010's | 26 (21.31) | 24.3611 |
| 2020's | 9 (7.38) | 2.80 |
| Authors | Studies |
|---|---|
| Levchuk, AA; Raushenbakh, MO | 1 |
| Birnbaum, D; Böttcher, F; König, A; Lutzmann, H; Samsonova, IA | 1 |
| Kimmig, J; Kreysel, HW; Meyerhoff, K | 1 |
| Dickerson, JW; Labadarios, D; McKenzie, DY; Parke, DV | 1 |
| Katz, E; Troost, T | 1 |
| Muramatsu, S; Suzuki, M; Takahashi, T; Watanabe, M; Yoshida, M | 1 |
| Chiancone, FM | 1 |
| Fokkens, W; Haije, WG; Hop, WC; Peters, HA; Portengen, H; Teulings, FA; van der Werf-Messing, B | 1 |
| Bell, ED | 1 |
| Arend, RA; Brown, RR; Huang, T; Kuntz, RE; Moore, JA | 1 |
| Raushenbakh, MO; Sergeeva, TI; Zharova, EI | 1 |
| Clark, JA; Clark, MS; Palfreyman, ES; Palfreyman, MG | 1 |
| Endou, H; Reuter, E; Weber, HJ | 1 |
| Ionascu, L; Ionescu, G; Romas, NA; Sholem, S; Veenema, RJ | 1 |
| Hankes, LV; Schmaeler, M | 1 |
| Birnbaum, D; Bode, R; Böttcher, F; Samsonova, IA | 1 |
| Brown, RR; Yeh, JK | 1 |
| Blonk, DI; Henkelman, MS; Lems, PH; Portengen, H; Teulings, FA | 1 |
| Baran, H; Schwarcz, R | 1 |
| Beninger, RJ; Bialik, M; Boegman, RJ; Jhamandas, K | 1 |
| Martin, F; Truscott, RJ | 1 |
| Schwarcz, R; Speciale, C; Ungerstedt, U | 1 |
| Dykens, JA; Stern, A; Sullivan, SG | 1 |
| Abdel-Hamied, HA; Abdel-Tawab, GA; Aboul-Azm, T; Ebied, SA; el-Kholy, ZA; el-Sharaky, AS; el-Toukhy, MA | 1 |
| Odink, J; Schrijver, J; van der Poll, JM; Vink, M | 1 |
| Evangelista, SJ; Rogers, KS | 1 |
| Shirasawa, E; Tomoda, A; Yoneyama, Y | 1 |
| Kuntze, I; Schievelbein, H | 1 |
| Ehrhart, H | 1 |
| Bühner, R; Bührlen, E; Byrd, D; Kochen, W | 1 |
| Murty, CN; Sidransky, H; Verney, E | 1 |
| Dutra de Oliveira, JE; Mello de Oliveira, JA; Vannucchi, H | 1 |
| Karawya, E; Mostafa, MH; Osman, N | 1 |
| Cook, JS; Pogson, CI | 1 |
| Krieter, P; Parli, CJ; Schmidt, B | 1 |
| Allegri, G; Cardin Dè Stefani, EL; Costa, C; De Antoni, A; Vanzan, S | 1 |
| Allegri, G; Cardin, EL; Costa, C; De Antoni, A; Vanzan, S | 1 |
| Arend, RA; Brown, RR; Wolf, H | 1 |
| Combs, GF; Poston, HA | 1 |
| Court, S; Edson, J; Lacey, K; McKiernan, J; Mellor, D | 1 |
| Chen, CY; Heyes, MP; Markey, SP; Naritsin, DB; Saito, K | 1 |
| Heyes, MP; Markey, SP; Saito, K | 1 |
| Hiraku, Y; Inoue, S; Kawanishi, S; Nishino, K; Oikawa, S; Tada, S; Yamamoto, K | 1 |
| Christen, S; Garner, B; Stocker, R; Thomas, SR | 1 |
| Heyes, MP; Major, EO; Markey, SP; Milstien, S; Saito, K; Vickers, JH | 1 |
| Heyes, MP; Markey, SP; Nowak, TS; Saito, K | 1 |
| Chen, CY; Crowley, JS; Heyes, MP; Markey, SP; Masana, M; Saito, K | 1 |
| Fornstedt-Wallin, B; Fredriksson, G; Luthman, J; Vänerman, E | 1 |
| Elderfield, AJ; Truscott, RJ | 1 |
| Watanabe, M | 1 |
| Acuña-Castroviejo, D; Molina-Carballo, A; Muñóz-Hoyos, A; Rodríguez-Cabezas, T; Ruiz-Cosano, C; Uberos-Fernández, J | 1 |
| Hasegawa, H; Hasegawa, Y; Ikeda, R; Nagamura, Y; Naito, J; Negishi, S | 1 |
| Fornstedt-Wallin, B; Fredriksson, G; Lundström, J; Luthman, J; Schwarcz, R | 1 |
| Brown, RR; Hankes, LV; Jansen, CR; Schmaeler, M | 1 |
| Stocker, R; Thomas, SR | 1 |
| Fujigaki, S; Fujii, H; Maekawa, N; Morita, T; Noma, A; Saito, K; Seishima, M; Takemura, M; Takeuchi, S; Wada, H | 2 |
| Hasegawa, Y; Ishiguro, I; Nagamura, Y; Naito, J; Negishi, S | 1 |
| Atwood, CS; Bowden, EF; Bush, AI; Chylack, LT; Faget, KY; Goldstein, LE; Hartshorn, M; Huang, X; Leopold, MC; Lim, JT; Muffat, JA; Saunders, AJ; Scarpa, RC; Tanzi, RE | 1 |
| Fukuwatari, T; Hayakawa, F; Morikawa, Y; Shibata, K; Sugimoto, E | 1 |
| Bauer, TM; Dufter, C; Opelz, G; Röse, L; Simon, H; Terness, P; Watzlik, A | 1 |
| Bianchi, R; Fallarino, F; Fioretti, MC; Grohmann, U; Orabona, C; Puccetti, P; Spreca, A; Vacca, C | 1 |
| Baran, H; Draxler, M; Kepplinger, B; Nohl, H; Staniek, K; Stur, J | 1 |
| COPPINI, D; MUSAJO, L; SPADA, A | 1 |
| HELLMANN, H; WISS, O | 1 |
| AURICCHIO, S; MARTUCCI, E; QUAGLIARIELLO, E | 2 |
| TOMPSETT, SL | 1 |
| GHOLSON, RK; HANKES, LV; HENDERSON, LM | 1 |
| BROWN, RR; HANKES, LV; LIPPINCOTT, S; SCHMAELER, M | 1 |
| GHOLSON, RK; HAYAISHI, O; ICHIYAMA, A; NISHIZUKA, Y | 1 |
| HAYAISHI, O; HONJO, T; ICHIYAMA, A; KAWAI, H; NAKAMURA, S; NISHIZUKA, Y; SENOH, S | 1 |
| Murgia, S; Rescigno, A; Sanjust, E; Soddu, G | 1 |
| Fukuoka, S; Fukuwatari, T; Ohsaki, S; Sasaki, R; Shibata, K; Suzuki, Y | 1 |
| Chae, SC; Choi, BM; Chung, HT; Lee, HS; Oh, GS; Pae, HO; Ryu, DG | 1 |
| HENDERSON, LM; HIRSCH, HM | 1 |
| Alegre, E; González, A; López, AS | 1 |
| Arbatova, J; D'Amato, E; Reeben, M; Vaarmann, A; Zharkovsky, A | 1 |
| Chung, HT; Kim, YM; Lee, BS; Oh, GS; Pae, HO; Rim, JS | 1 |
| Chiarugi, A; Feder-Mengus, C; Frey, DM; Heberer, M; Misteli, H; Oertli, D; Reschner, A; Rosenthal, R; Schumacher, R; Spagnoli, GC; Weber, WP; Zajac, P | 1 |
| Alegre, E; Carosella, E; González, A; LeMaoult, J; López, AS | 1 |
| Darlington, LG; Forrest, CM; Mackay, GM; Oxford, L; Stone, TW; Stoy, N | 1 |
| Bauer, TM; Baumeister, S; Bosch, N; Gebhard, MM; Germann, G; Jiga, L; Kleist, C; Opelz, G; Radu, CA; Terness, P | 1 |
| Fukuwatari, T; Shibata, K | 1 |
| Cwik, M; Llenos, IC; Miller, CL; Walkup, J; Weis, S | 1 |
| Backhaus, C; Hardeland, R; Laatsch, H; Rahman, H; Scheffler, S | 1 |
| Dai, X; Zhu, BT | 1 |
| Babb, JS; Gabbay, V; Gonen, O; Katz, Y; Klein, RG; Liebes, L; Liu, S; Mendoza, S | 1 |
| Alonso, CM; Babb, JS; Gabbay, V; Guttman, LE; Hirsch, GS; Katz, Y; Klein, RG; Liebes, L; Mendoza, S | 1 |
| Murray, MF | 1 |
| Aweeka, F; Barbour, JD; Brenchley, JM; Deeks, SG; Douek, DC; Favre, D; Hecht, FM; Huang, Y; Hunt, PW; Jayawardene, A; Kanwar, B; Loke, P; Lowe, MM; Martin, JN; McCune, JM; Mold, J; Seu, L | 1 |
| Aerts, T; Brouns, R; De Deyn, PP; De Surgeloose, D; Scharpé, S; Verkerk, R; Wauters, A | 1 |
| Choi, I; Choi, IW; Choi, JH; Joo, YD; Lee, JN; Lee, SM; Lee, WS; Lee, YS; Park, SG; Seo, SK | 1 |
| Du Preez, JL; Harvey, BH; Möller, M | 1 |
| Kolodziej, L | 2 |
| Fukuwatari, T; Kondo, R; Sano, M; Shibata, K | 1 |
| Eussen, SJ; Midttun, Ø; Nygård, O; Tell, GS; Theofylaktopoulou, D; Ueland, PM; Ulvik, A; Vollset, SE | 1 |
| Fukuwatari, T; Funakoshi, H; Kadota, E; Kanai, M; Nakamura, T; Sano, M; Shibata, K; Terakata, M | 1 |
| Choi, I; Choi, IW; Joo, YD; Kang, SW; Kim, MK; Lee, SM; Lee, WS; Park, SG; Park, SJ; Seo, SK | 1 |
| Cao, X; Hou, W; Huang, G; Li, Y; Zhang, J; Zhang, Y | 1 |
| Barlera, S; Fracasso, C; Gobbi, M; Guiso, G; Kurola, J; Latini, R; Lucchetti, J; Masson, S; Montanelli, A; Pettilä, V; Ristagno, G; Skrifvars, MB; Tiainen, M; Vaahersalo, J; Varpula, T | 1 |
| Fukuwatari, T; Kobayashi, R; Shibata, K | 1 |
| Fukuwatari, T; Ohno, T; Sano, M; Shibata, K | 1 |
| Brody, LC; Brosnan, JT; Brosnan, ME; Deac, OM; Fan, R; Gibney, ER; Laird, E; Midttun, Ø; Mills, JL; Molloy, AM; Shane, B; Ueland, PM; Wang, Y | 1 |
| Oxenkrug, GF | 1 |
| Chi, YY; Coats, B; Gregory, JF; Midttun, Ø; Ralat, M; Rios-Avila, L; Stacpoole, PW; Ueland, PM | 1 |
| Badawy, AA; Bano, S | 1 |
| Dierkes, J; Drevon, CA; Gudbrandsen, OA; Karlsson, T; Midttun, Ø; Nygård, O; Pedersen, ER; Strand, E; Ueland, PM; Øyen, J | 1 |
| Brody, LC; Deac, OM; Fan, R; Gardiner, CM; Lu, Z; McCann, A; Meyer, K; Midttun, Ø; Mills, JL; Molloy, AM; Quinn, L; Shane, B; Ueland, PM | 1 |
| Advani, R; Giil, LM; Midttun, Ø; Refsum, H; Smith, AD; Ueland, PM; Ulvik, A | 1 |
| Shibata, K | 1 |
| Chen, H; Chen, Y; Shi, G; Yang, M; Zhang, S; Zheng, F; Zheng, Z; Zhong, S | 1 |
| Becquemont, L; Boniface, B; Boursier-Neyret, C; Chanson, P; Colle, R; Corruble, E; David, DJ; Falissard, B; Fève, B; Masson, P; Verstuyft, C; Walther, B; Werner, E | 1 |
| Allers, KA; Harkin, A; McLoughlin, DM; Ryan, KM | 1 |
| Enomoto, N; Fujisawa, T; Furuhashi, K; Hozumi, H; Inui, N; Karayama, M; Maekawa, M; Masuda, J; Mori, K; Nakamura, Y; Suda, T; Sugimura, H; Suzuki, Y; Takada, A; Yasui, H | 1 |
| Cui, C; Lin, J; Sun-Waterhouse, D | 1 |
| Bugiani, M; Dijkhuis, A; Duitman, JW; Geeraerts, Z; Guo, L; Lutter, R; Nossent, EJ; Roos, E; Schurink, B; van der Valk, P; van Vught, L; Vaz, FM; Vlaar, AP; Yeh, SR | 1 |
| Deng, P; Jiang, H; Li, K; Long, D; Peng, J; Wang, K; Zeng, J | 1 |
| Asakawa, T; Chen, W; Jia, X; Qin, W; Shi, Y | 1 |
| Antony, J; Ardern-Holmes, S; Bandodkar, S; Dale, RC; Gill, D; Guillemin, GJ; Guller, A; Gupta, S; Han, VX; Heng, B; Innes, EA; Jones, HF; Kothur, K; Menezes, MP; Mohammad, S; Patel, S; Pires, AS; Tantsis, E; Troedson, C; Tsang, E; Webster, R; Wienholt, L; Yan, J | 1 |
| Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S | 1 |
6 review(s) available for tryptophan and 3-hydroxyanthranilic acid
| Article | Year |
|---|---|
[Microanalysis of tryptophan metabolites].
Topics: 3-Hydroxyanthranilic Acid; Animals; Fluorometry; Humans; Kynurenic Acid; Kynurenine; Mice; Microchemistry; Tryptophan; Ultraviolet Rays; Urinary Bladder Neoplasms | 1997 |
Antioxidant activities and redox regulation of interferon-gamma-induced tryptophan metabolism in human monocytes and macrophages.
Topics: 3-Hydroxyanthranilic Acid; Antioxidants; Drug Synergism; Humans; Interferon-gamma; Lipoproteins, LDL; Macrophages; Monocytes; Oxidation-Reduction; Tryptophan; Vitamin E | 1999 |
Organ Co-Relationship in Tryptophan Metabolism and Factors That Govern the Biosynthesis of Nicotinamide from Tryptophan.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Diet; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Liver; Niacinamide; Nutritional Status; Pentosyltransferases; Quinolinic Acid; Tryptophan; Vitamin B Deficiency; Xanthurenates | 2018 |
The therapeutic potential of diet on immune-related diseases: based on the regulation on tryptophan metabolism.
Topics: 3-Hydroxyanthranilic Acid; Diet; Indoles; Kynurenine; Tryptophan | 2022 |
Can kynurenine pathway be considered as a next-generation therapeutic target for Parkinson's disease? An update information.
Topics: 3-Hydroxyanthranilic Acid; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Levodopa; Parkinson Disease; Quinolinic Acid; Tryptophan | 2022 |
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan | 2022 |
116 other study(ies) available for tryptophan and 3-hydroxyanthranilic acid
| Article | Year |
|---|---|
[Induction of tyrosine aminotransferase by blastomogenic metabolites of tryptophan and tyrosine].
Topics: 3-Hydroxyanthranilic Acid; Animals; Carcinogens; Enzyme Induction; Lactates; Liver; Male; ortho-Aminobenzoates; Phenols; Rats; Tryptophan; Tyrosine; Tyrosine Transaminase | 1976 |
[De novo biosynthesis of nicotinic acid in candida lipolytica].
Topics: 3-Hydroxyanthranilic Acid; Arylformamidase; Candida; Hydrolases; Kynurenine; Methylnitronitrosoguanidine; Mixed Function Oxygenases; Mutagens; Mutation; Nicotinic Acids; Rhodotorula; Tryptophan; Tryptophan Oxygenase | 1975 |
[Tryptophan-load in progressive scleroderma (author's transl)].
Topics: 3-Hydroxyanthranilic Acid; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Male; Niacinamide; Scleroderma, Systemic; Serotonin; Skin; Tryptamines; Tryptophan; Xanthurenates | 1976 |
Metabolic abnormalities of tryptophan and nicotinic acid in patients with rheumatoid arthritis.
Topics: 3-Hydroxyanthranilic Acid; Arthritis, Rheumatoid; Feeding Behavior; Humans; Kynuramine; Niacinamide; Nicotinic Acids; Tryptophan; Xanthurenates | 1978 |
Phenoxazinone biosynthesis: accumulation of a precursor, 4-methyl-3-hydroxyanthranilic acid, by mutants of Streptomyces parvulus.
Topics: 3-Hydroxyanthranilic Acid; Dactinomycin; Mutation; ortho-Aminobenzoates; Oxazines; Protoplasts; Streptomyces; Tryptophan | 1979 |
Relationship between tryptophan intake and urinary excretion of 3-hydroxy-kynurenine, 3-hydroxyanthranilic acid, xanthurenic acid and kynurenic acid.
Topics: 3-Hydroxyanthranilic Acid; Adult; Female; Humans; Kinetics; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Tryptophan; Xanthurenates | 1979 |
[Changes in opposite directions of tryptophanpyrrolase and 3-OH-anthranilic oxidase after a loading dose of tryptophan].
Topics: 3-Hydroxyanthranilic Acid; Animals; Kidney; Liver; Oxygenases; Prednisolone; Rats; Tryptophan; Tryptophan Oxygenase | 1978 |
A new aspect of the urinary excretion of tryptophan metabolites in patients with cancer of the bladder.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Aspartate Aminotransferases; Creatinine; Female; Humans; Kidney Neoplasms; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Sodium; Tryptophan; Urea; Ureteral Obstruction; Urinary Bladder Neoplasms; Xanthurenates | 1978 |
Tryptophan metabolism in Japanese and British women and its relationship to endogenous steroid levels.
Topics: 3-Hydroxyanthranilic Acid; Asian People; Breast Neoplasms; Estradiol; Female; Hormones; Humans; Hydrocortisone; Japan; Kynurenine; Menopause; Tryptophan; United Kingdom; White People; Xanthurenates | 1978 |
Experimental biharzial bladder cancer: tryptophan metabolism in nonhuman primates experimentally infected with Schistosoma haematobium.
Topics: 3-Hydroxyanthranilic Acid; Animals; Disease Models, Animal; Haplorhini; Kynurenine; Liver; Neoplasms, Experimental; Papio; Schistosomiasis; Tryptophan; Tryptophan Oxygenase | 1976 |
[Morphologic changes in the urinary bladder of mice induced by metabolites of tryptophan and tyrosine].
Topics: 3-Hydroxyanthranilic Acid; Acetophenones; Acrylates; Animals; Carcinogens; Indoles; Lactates; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phenols; Phenylpyruvic Acids; Precancerous Conditions; Tryptophan; Tyrosine; Urinary Bladder Neoplasms | 1976 |
The effect of tryptophan and a tryptophan/5-hydroxytryptophan combination on indoles in the brains of rats fed a tryptophan deficient diet.
Topics: 3-Hydroxyanthranilic Acid; 5-Hydroxytryptophan; Animals; Brain; Depression; Diet; Drug Synergism; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase | 1975 |
Inhibition of gluconeogenesis in rat renal cortex slices by metabolites of L-tryptophan in vitro.
Topics: 3-Hydroxyanthranilic Acid; Adenosine Triphosphate; Animals; Depression, Chemical; Dihydroxyacetone; Gluconeogenesis; In Vitro Techniques; Kidney Cortex; Liver; Magnesium; Male; ortho-Aminobenzoates; Oxaloacetates; Oxygen Consumption; Phosphoenolpyruvate Carboxykinase (GTP); Pyridines; Quinolinic Acids; Rats; Tryptophan | 1975 |
A new method for determination of urinary tryptophan metabolites in bladder carcinoma.
Topics: 3-Hydroxyanthranilic Acid; Chromatography, Thin Layer; Female; Humans; Kynurenic Acid; Kynurenine; Male; Spectrometry, Fluorescence; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates | 1975 |
The uptake of 14C-labeled hydroxyanthranilic acid and enantiomers of tryptophan, kynurenine, and hydroxykynurenine in human blood.
Topics: 3-Hydroxyanthranilic Acid; Adult; Female; Humans; Isomerism; Kynurenine; Middle Aged; ortho-Aminobenzoates; Scleroderma, Systemic; Tryptophan | 1975 |
[The short circuit way-- the only way of ne novo biosynthesis of nicotinic acid in Hansenula henricii].
Topics: 3-Hydroxyanthranilic Acid; Ascomycota; Methylnitronitrosoguanidine; Mutagens; Mutation; Nicotinic Acids; ortho-Aminobenzoates; Phenotype; Pichia; Rhodotorula; Species Specificity; Tryptophan | 1975 |
Urinary tryptophan metabolites: assay of free and acid hydrolyzable conjugates of 3-hydroxykynurenine and 3-hydroxyanthranilic acid.
Topics: 3-Hydroxyanthranilic Acid; Colorimetry; Humans; Kynurenine; ortho-Aminobenzoates; Temperature; Tryptophan | 1975 |
The action of 3-hydroxyanthranilic acid and other tryptophan metabolites on stimulated human lymphocytes.
Topics: 3-Hydroxyanthranilic Acid; Adenosine Triphosphate; DNA; Humans; Lymphocyte Activation; Lymphocytes; ortho-Aminobenzoates; Thymidine; Tryptophan | 1975 |
Evidence for the preferential production of 3-hydroxyanthranilic acid from anthranilic acid in the rat brain.
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Kynurenine; Male; Mixed Function Oxygenases; Organ Specificity; ortho-Aminobenzoates; Rats; Rats, Inbred Strains; Tryptophan | 1991 |
Quinolinate-induced cortical cholinergic damage: modulation by tryptophan metabolites.
Topics: 3-Hydroxyanthranilic Acid; Acetylcholine; Animals; Brain; Cerebral Cortex; In Vitro Techniques; Kynurenic Acid; Male; Neurotoxins; Parietal Lobe; Picolinic Acids; Potassium; Quinolines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1990 |
The reaction of proteins with 3-hydroxyanthranilic acid as a possible model for senile nuclear cataract in man.
Topics: 3-Hydroxyanthranilic Acid; Animals; Cataract; Cattle; Chromatography, Gel; Color; Crystallins; Humans; Hydrogen Peroxide; Lysine; Methionine; Models, Biological; Molecular Weight; ortho-Aminobenzoates; Oxidation-Reduction; Serum Albumin, Bovine; Sulfhydryl Compounds; Time Factors; Tryptophan | 1989 |
Production of extracellular quinolinic acid in the striatum studied by microdialysis in unanesthetized rats.
Topics: 3-Hydroxyanthranilic Acid; Animals; Corpus Striatum; Extracellular Space; Ibotenic Acid; Kynurenic Acid; Male; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan | 1989 |
Oxidative reactivity of the tryptophan metabolites 3-hydroxyanthranilate, cinnabarinate, quinolinate and picolinate.
Topics: 3-Hydroxyanthranilic Acid; Catalase; Hydrogen-Ion Concentration; Kinetics; ortho-Aminobenzoates; Oxazines; Oxidation-Reduction; Oxygen Consumption; Picolinic Acids; Pyridines; Quinolinic Acid; Quinolinic Acids; Superoxide Dismutase; Tryptophan | 1987 |
The correlation between certain tryptophan metabolites and the N-nitrosamine content in the urine of bilharzial bladder cancer patients.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aminohippuric Acids; Colorimetry; Humans; Indican; Kynurenic Acid; Kynurenine; Male; Middle Aged; Nitrosamines; ortho-Aminobenzoates; Schistosomiasis haematobia; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates | 1986 |
Influence of tryptophan loading on urinary excretion of anthranilic acid and 3-hydroxyanthranilic acid by men and women as determined by alkali flame ionization gas chromatography.
Topics: 3-Hydroxyanthranilic Acid; Adult; Anticonvulsants; Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Indicators and Reagents; Kinetics; Male; ortho-Aminobenzoates; Sex Factors; Tryptophan | 1986 |
3-Hydroxykynurenine, 3-hydroxyanthranilic acid, and o-aminophenol inhibit leucine-stimulated insulin release from rat pancreatic islets.
Topics: 3-Hydroxyanthranilic Acid; Aminophenols; Animals; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kynurenine; Leucine; Male; ortho-Aminobenzoates; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tryptophan | 1985 |
Reactions of oxy- and methemoglobin with tryptophan metabolites, 3-hydroxyanthranilic acid and 3-hydroxykynurenine.
Topics: 3-Hydroxyanthranilic Acid; Humans; Kinetics; Kynurenine; Methemoglobin; ortho-Aminobenzoates; Oxidation-Reduction; Oxyhemoglobins; Phytic Acid; Protein Binding; Spectrophotometry; Structure-Activity Relationship; Tryptophan | 1986 |
[Proceedings: Tryptophan metabolism, bladder carcinoma and smoking habits].
Topics: 3-Hydroxyanthranilic Acid; Carcinoma; Humans; Kynurenine; Niacinamide; Smoking; Tryptophan; Urinary Bladder Neoplasms | 1972 |
[Proceedings: Endogenous carcinogens. Experimental induction of malignant tumors and leukemias by the tryptophan metabolites 3-hydroxyanthranilic acid and 3-hydroxykynurenine].
Topics: 3-Hydroxyanthranilic Acid; Animals; Carcinoma; Kynurenine; Leukemia, Experimental; Lung Neoplasms; Mice; Neoplasms, Experimental; ortho-Aminobenzoates; Tryptophan; Urinary Bladder Neoplasms | 1972 |
[Proceedings: Tryptophan metabolism in untreated phenylketonuria and in vitamin B6 dependent cramps].
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Carboxylic Acids; Child; Child, Preschool; Humans; Hydroxyquinolines; Intellectual Disability; Kynurenic Acid; Kynurenine; Muscle Cramp; Nicotinic Acids; Phenylalanine; Phenylketonurias; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates | 1972 |
Studies on the influence of tryptophan and related compounds on hepatic polyribosomes and protein synthesis in the rat.
Topics: 3-Hydroxyanthranilic Acid; 5-Hydroxytryptophan; Animals; Cell Nucleus; Cytoplasm; Female; Indoles; Liver; Poly A; Polyribosomes; Protein Biosynthesis; Puromycin; Rats; RNA; RNA, Messenger; Tryptophan | 1980 |
Tryptophan metabolism in alcoholic pellagra patients: measurements of urinary metabolites and histochemical studies of related muscle enzymes.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Alcoholism; Aspartate Aminotransferases; Glycerolphosphate Dehydrogenase; Humans; Male; Middle Aged; Muscles; Niacinamide; Nutrition Disorders; Oxidoreductases; Pellagra; Pyridones; Tryptophan | 1982 |
The kinetic mechanism of inhibition of liver pyridoxal kinase with tryptophan metabolites.
Topics: 3-Hydroxyanthranilic Acid; Animals; Kinetics; Kynurenine; Liver; Phosphotransferases; Pyridoxal Kinase; Quinolinic Acids; Sheep; Tryptophan; Xanthurenates | 1981 |
Tryptophan and glucose metabolism in rat liver cells. The effects of DL-6-chlorotryptophan, 4-chloro-3-hydroxyanthranilate and pyrazinamide.
Topics: 3-Hydroxyanthranilic Acid; Animals; Gluconeogenesis; In Vitro Techniques; Liver; Male; ortho-Aminobenzoates; Pyrazinamide; Rats; Rats, Inbred Strains; Tryptophan | 1983 |
Metabolism of 6-chlorotryptophan to 4-chloro-3-hydroxyanthranilic acid: a potent inhibitor of 3-hydroxyanthranilic acid oxidase.
Topics: 3-Hydroxyanthranilic Acid; Animals; Guinea Pigs; Kinetics; Liver; Male; ortho-Aminobenzoates; Oxidoreductases; Rats; Sweetening Agents; Tryptophan | 1980 |
Alterations of the tryptophan--nicotinic acid metabolism in vitiligo.
Topics: 3-Hydroxyanthranilic Acid; Adult; Female; Humans; Hydrolases; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Male; Melanins; Mixed Function Oxygenases; Models, Biological; Niacin; Tryptophan; Vitiligo; Xanthurenates | 1982 |
[Tryptophan metabolism in patients with vitiligo].
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Aminohippuric Acids; Female; Humans; Male; Middle Aged; Tryptophan; Vitiligo; Xanthurenates | 1981 |
The kynurenine load test, an adjunct to the tryptophan load test.
Topics: 3-Hydroxyanthranilic Acid; Aged; Female; Humans; Kynurenine; Menopause; Middle Aged; NAD; Pyridoxine; Tryptophan | 1980 |
Nutritional implications of tryptophan catabolizing enzymes in several species of trout and salmon.
Topics: 3-Hydroxyanthranilic Acid; Animals; Fishes; Liver; Nicotinic Acids; ortho-Aminobenzoates; Picolinic Acids; Tryptophan | 1980 |
Hydroxykynurenine/hydroxyanthranilic acid ratios and febrile convulsions.
Topics: 3-Hydroxyanthranilic Acid; Child, Preschool; Humans; Infant; Kynurenine; ortho-Aminobenzoates; Seizures; Seizures, Febrile; Time Factors; Tryptophan | 1980 |
Metabolism of L-tryptophan to kynurenate and quinolinate in the central nervous system: effects of 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Topics: 3-Hydroxyanthranilic Acid; Animals; Cell Line; Central Nervous System; Gas Chromatography-Mass Spectrometry; Humans; Kynurenic Acid; Kynurenine; Lyases; Macaca mulatta; Quinolinic Acid; Transaminases; Tryptophan | 1995 |
6-Chloro-D,L-tryptophan, 4-chloro-3-hydroxyanthranilate and dexamethasone attenuate quinolinic acid accumulation in brain and blood following systemic immune activation.
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Dexamethasone; Immune System; Kynurenine; Lung; Male; Mice; Mice, Inbred C57BL; Pokeweed Mitogens; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase | 1994 |
Metal-mediated oxidative damage to cellular and isolated DNA by certain tryptophan metabolites.
Topics: 3-Hydroxyanthranilic Acid; Animals; Autoradiography; Base Sequence; Carcinogens; Cattle; Cells, Cultured; Copper; DNA; DNA Damage; Free Radical Scavengers; Genes, ras; Humans; Indicators and Reagents; Kynurenine; Manganese Poisoning; Molecular Sequence Data; Oxidation-Reduction; Phenanthrolines; Phosphorus Radioisotopes; Spectrophotometry, Ultraviolet; Tryptophan | 1995 |
Inhibition by interferon-gamma of human mononuclear cell-mediated low density lipoprotein oxidation. Participation of tryptophan metabolism along the kynurenine pathway.
Topics: 3-Hydroxyanthranilic Acid; Cholesterol Esters; Dose-Response Relationship, Drug; Enzyme Induction; Fatty Acids, Unsaturated; Humans; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Lipoproteins, LDL; Onium Compounds; Oxidation-Reduction; Peroxides; Tryptophan; Tryptophan Oxygenase; Vitamin E | 1994 |
A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate.
Topics: 3-Hydroxyanthranilic Acid; Animals; Biopterins; Brain; Encephalitis; Fetus; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Macaca mulatta; Myelitis; Neopterin; Poliomyelitis; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase | 1993 |
Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia.
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Female; Gerbillinae; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ischemic Attack, Transient; Kynurenine; Macrophages; Pokeweed Mitogens; Quinolinic Acid; Time Factors; Tryptophan; Tryptophan Oxygenase | 1993 |
4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells).
Topics: 3-Hydroxyanthranilic Acid; Animals; Brain; Carbolines; Cell Line; Harmine; Humans; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Macrophages; Quinolinic Acid; Rats; Tryptophan; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Regulation of quinolinic acid in the normal rat brain by kynurenine pathway precursors.
Topics: 3-Hydroxyanthranilic Acid; Analysis of Variance; Animals; Cerebral Ventricles; Hippocampus; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Kynurenine; Male; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Stereoisomerism; Tryptophan | 1996 |
Is an altered tryptophan metabolism responsible for age-related cataract?
Topics: 3-Hydroxyanthranilic Acid; Aged; Cataract; Chromatography, High Pressure Liquid; Female; Humans; Kynurenine; Male; Reference Values; Sensitivity and Specificity; Tryptophan | 1996 |
Relationships between methoxyindole and kynurenine pathway metabolites in plasma and urine in children suffering from febrile and epileptic seizures.
Topics: 3-Hydroxyanthranilic Acid; Child; Child, Preschool; Circadian Rhythm; Epilepsy; Female; Humans; Infant; Kynurenic Acid; Kynurenine; Male; Melatonin; Seizures, Febrile; Tryptophan; Xanthurenates | 1997 |
Ommochrome deficiency in an albino strain of a terrestrial isopod, Armadillidium vulgare.
Topics: 3-Hydroxyanthranilic Acid; Amino Acids; Animals; Crustacea; Female; Hydrolases; Kynurenine; Kynurenine 3-Monooxygenase; Male; Mixed Function Oxygenases; Oxazines; Phenothiazines; Phenotype; Pigmentation; Pigments, Biological; Sex Factors; Tryptophan; Tryptophan Oxygenase; Xanthenes | 1999 |
3-Hydroxyanthranilic acid accumulation following administration of the 3-hydroxyanthranilic acid 3,4-dioxygenase inhibitor NCR-631.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Brain; Dioxygenases; Enzyme Inhibitors; Hydroxyindoleacetic Acid; Kynurenic Acid; Male; Oxygenases; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Serotonin; Tryptophan | 1999 |
Vitamin effects on tryptophan-niacin metabolism in primary hepatoma patients.
Topics: 3-Hydroxyanthranilic Acid; Biotransformation; Black People; Carbon Radioisotopes; Carcinoma, Hepatocellular; Dietary Supplements; Humans; Liver Neoplasms; Male; Niacin; Nutritional Physiological Phenomena; Pyridoxine; Riboflavin; South Africa; Thiamine; Tryptophan; Vitamins | 1999 |
L-tryptophan-kynurenine pathway metabolite 3-hydroxyanthranilic acid induces apoptosis in macrophage-derived cells under pathophysiological conditions.
Topics: 3-Hydroxyanthranilic Acid; Apoptosis; Humans; Kynurenine; Macrophages; Tryptophan; Tumor Cells, Cultured; U937 Cells | 1999 |
Involvement of tryptophan metabolism in the body color of crustacea.
Topics: 3-Hydroxyanthranilic Acid; Animals; Crustacea; Kynurenine; Mutation; Phenothiazines; Pigmentation; Pigments, Biological; Tryptophan | 1999 |
3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction.
Topics: 3-Hydroxyanthranilic Acid; Animals; Ascorbic Acid; Cataract; Cattle; Copper; Crystallins; Electrochemistry; Humans; Hydrogen Peroxide; Iron; Kynurenine; Lens, Crystalline; Metals; Oxidation-Reduction; Superoxides; Tryptophan | 2000 |
3-Hydroxyanthranilic acid, an L-tryptophan metabolite, induces apoptosis in monocyte-derived cells stimulated by interferon-gamma.
Topics: 3-Hydroxyanthranilic Acid; Antioxidants; Apoptosis; Cell Line; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Interferon-gamma; Kynurenine; Monocytes; Spectrophotometry; Tryptophan; Tumor Cells, Cultured; U937 Cells; Xanthine Oxidase | 2001 |
Influence of adenine-induced renal failure on tryptophan-niacin metabolism in rats.
Topics: 3-Hydroxyanthranilic Acid; Adenine; Animals; Kidney; Kynurenic Acid; Liver; Male; NAD; Niacin; Quinolinic Acid; Rats; Rats, Wistar; Renal Insufficiency; Tryptophan; Xanthurenates | 2001 |
Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells: mediation of suppression by tryptophan metabolites.
Topics: 3-Hydroxyanthranilic Acid; Cell Death; Cell Division; Cytotoxicity Tests, Immunologic; Dendritic Cells; Gene Expression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lymphocyte Activation; T-Lymphocytes; Time Factors; Tryptophan; Tryptophan Oxygenase | 2002 |
T cell apoptosis by tryptophan catabolism.
Topics: 3-Hydroxyanthranilic Acid; Animals; Apoptosis; Autoimmune Diseases; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Nucleus; Cells, Cultured; Cytochrome c Group; Cytosol; Dose-Response Relationship, Drug; fas Receptor; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Electron; Mitochondria; Quinolinic Acid; Self Tolerance; T-Lymphocytes; Th1 Cells; Thymus Gland; Tryptophan | 2002 |
Kynurenines and the respiratory parameters on rat heart mitochondria.
Topics: 3-Hydroxyanthranilic Acid; Animals; Free Radical Scavengers; In Vitro Techniques; Kinetics; Kynurenine; Male; Mitochondria, Heart; Mitochondrial Proteins; NAD; ortho-Aminobenzoates; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Succinates; Tryptophan | 2003 |
Isolation of 3-hydroxyanthranilic acid from pathological human urine after administration of L-tryptophan.
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Body Fluids; Humans; Tryptophan; Tuberculosis; Tuberculosis, Pulmonary | 1952 |
[Phosphate of 3-oxyanthranilic acid, metabolite of tryptophane].
Topics: Biochemical Phenomena; ortho-Aminobenzoates; Phosphates; Tryptophan | 1952 |
[The effect of tryptophan and 3-hydroxyanthranilic acid on the formation of inclusion bodies in the erythrocytes of mice treated with synkavit (sodium 2-methyl-1,4-naphthalenediol diphosphate)].
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Animals; Antifibrinolytic Agents; Diphosphates; Erythrocytes; Inclusion Bodies; Mice; Sodium; Tryptophan; Vitamin K | 1958 |
[Effect of tryptophan & 3-hydroxyanthranilic acid on formation of inner bodies in erythrocytes in synkavit-treated mice].
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Animals; Erythrocytes; Mice; Naphthoquinones; Tryptophan; Vitamin K | 1958 |
The determination in urine of some metabolites of tryptophankynurenine, anthranilic acid and 3-hydroxyanthranilic acid- and reference to the presence of o-aminophenol in urine.
Topics: 3-Hydroxyanthranilic Acid; Aminobenzoates; Aminophenols; Humans; Kynurenine; ortho-Aminobenzoates; Phenols; Tryptophan | 1959 |
3-Hydroxyanthranilic acid as an intermediate in the oxidation of the indole nucleus of tryptophan.
Topics: 3-Hydroxyanthranilic Acid; Indoles; ortho-Aminobenzoates; Tryptophan | 1960 |
METABOLISM OF 3-HYDROXYANTHRANILIC ACID-CARBOXYL-C14 IN THE HUMAN.
Topics: 3-Hydroxyanthranilic Acid; Achondroplasia; Blood; Carbon Isotopes; Chromatography; Hippurates; Humans; Kynurenic Acid; Kynurenine; Metabolism; Niacin; Niacinamide; Nicotinic Acids; ortho-Aminobenzoates; Pyridines; Rats; Research; Tryptophan; Urine; Xanthurenates | 1964 |
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. I. ENZYMIC FORMATION OF GLUTARIC ACID FROM 3-HYDROXYANTHRANILIC ACID.
Topics: 3-Hydroxyanthranilic Acid; Amino Acids; Animals; Benzene; Carbon Dioxide; Carbon Isotopes; Cats; Chromatography; Coenzyme A; Electrophoresis; Glutarates; Keto Acids; Kynurenine; Liver; Metabolism; NAD; ortho-Aminobenzoates; Pseudomonas; Pyridines; Research; Tryptophan | 1965 |
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. II. ENZYMIC FORMATION OF ALPHA-AMINOMUCONIC ACID FROM 3-HYDROXYANTHRANILIC ACID.
Topics: 3-Hydroxyanthranilic Acid; Acids; Aldehydes; Animals; Benzene; Carboxy-Lyases; Cats; Chromatography; Dicarboxylic Acids; Edetic Acid; Electrophoresis; Hydrogen-Ion Concentration; Liver; Metabolism; NAD; ortho-Aminobenzoates; Oxidoreductases; Pyridines; Research; Tryptophan | 1965 |
Interference of some tryptophan metabolites in the formation of melanin in vitro.
Topics: 3-Hydroxyanthranilic Acid; Agaricales; Catalysis; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; In Vitro Techniques; Kynurenine; Magnetic Resonance Spectroscopy; Melanins; Models, Chemical; Monophenol Monooxygenase; Oxygen; Pigmentation; Spectrophotometry; Time Factors; Tryptophan; Tyrosine; Ultraviolet Rays | 2004 |
The effects of phthalate esters on the tryptophan-niacin metabolism.
Topics: 3-Hydroxyanthranilic Acid; Animals; Dibutyl Phthalate; Diethylhexyl Phthalate; Kynurenic Acid; Liver; Male; NAD; Niacin; ortho-Aminobenzoates; Phthalic Acids; Plasticizers; Rats; Rats, Wistar; Tryptophan; Xanthurenates | 2003 |
3-Hydroxyanthranilic acid, one of metabolites of tryptophan via indoleamine 2,3-dioxygenase pathway, suppresses inducible nitric oxide synthase expression by enhancing heme oxygenase-1 expression.
Topics: 3-Hydroxyanthranilic Acid; Animals; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Lipopolysaccharides; Macrophages; Membrane Proteins; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Signal Transduction; Tryptophan; Tryptophan Oxygenase | 2004 |
Quinolinic acid metabolism; urinary excretion by the rat following tryptophan and 3-hydroxyanthranilic acid administration.
Topics: 3-Hydroxyanthranilic Acid; Animals; Body Fluids; Quinolines; Quinolinic Acid; Rats; Tryptophan; Urine | 1949 |
Tryptophan metabolites interfere with the Ehrlich reaction used for the measurement of kynurenine.
Topics: 3-Hydroxyanthranilic Acid; Benzaldehydes; Chromatography, High Pressure Liquid; Humans; Kynurenine; Monocytes; Tryptophan | 2005 |
Reduced serotonin and 3-hydroxyanthranilic acid levels in serum of cystatin B-deficient mice, a model system for progressive myoclonus epilepsy.
Topics: 3-Hydroxyanthranilic Acid; Adult; Animals; Chromatography, High Pressure Liquid; Cystatin B; Cystatins; Disease Models, Animal; Female; Humans; Kynurenine; Male; Mice; Myoclonic Epilepsies, Progressive; Serotonin; Tryptophan | 2005 |
3-Hydroxyanthranilic acid, one of L-tryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and vascular cell adhesion molecule-1 expression via heme oxygenase-1 induction in human umbilical vein endothelial cells.
Topics: 3-Hydroxyanthranilic Acid; Antioxidants; Atherosclerosis; Bilirubin; Chemokine CCL2; Endothelium, Vascular; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Humans; NF-E2-Related Factor 2; NF-kappa B; Response Elements; Tryptophan; Tumor Necrosis Factor-alpha; Umbilical Veins; Vascular Cell Adhesion Molecule-1 | 2006 |
Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines.
Topics: 3-Hydroxyanthranilic Acid; Antigen Presentation; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cytokines; Dendritic Cells; Free Radical Scavengers; Homeostasis; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Melanoma; Neoplasm Proteins; Receptors, Antigen, T-Cell; Tryptophan | 2006 |
Regulatory role of tryptophan degradation pathway in HLA-G expression by human monocyte-derived dendritic cells.
Topics: 3-Hydroxyanthranilic Acid; Cell Line, Tumor; Cell Separation; Dendritic Cells; Histocompatibility Antigens Class I; HLA Antigens; HLA-G Antigens; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Lipopolysaccharides; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Monocytes; Protein Processing, Post-Translational; T-Lymphocytes; Tryptophan | 2006 |
Kynurenine pathway metabolism in patients with osteoporosis after 2 years of drug treatment.
Topics: 3-Hydroxyanthranilic Acid; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethacin; Kynurenic Acid; Kynurenine; Lipid Peroxidation; Male; Middle Aged; Molecular Structure; Neopterin; ortho-Aminobenzoates; Osteoporosis; Sodium Salicylate; Tryptophan | 2006 |
Immunosuppressive effect of tryptophan metabolites in composite tissue allotransplantation.
Topics: 3-Hydroxyanthranilic Acid; Animals; Graft Rejection; Hindlimb; Immune Tolerance; Immunosuppressive Agents; Injections, Intramuscular; Kynurenine; Models, Animal; Rats; Rats, Inbred Lew; Tacrolimus; Tissue Transplantation; Tryptophan | 2007 |
Effect of nicotinamide administration on the tryptophan-nicotinamide pathway in humans.
Topics: 3-Hydroxyanthranilic Acid; Adult; Chromatography, High Pressure Liquid; Feedback, Physiological; Female; Humans; Kynurenic Acid; Niacinamide; ortho-Aminobenzoates; Quinolinic Acid; Tryptophan; Xanthurenates | 2007 |
Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Bipolar Disorder; Brain; Chromatography, High Pressure Liquid; Female; Gyrus Cinguli; Humans; Kynurenine; Middle Aged; Niacinamide; Predictive Value of Tests; Schizophrenia; Signal Transduction; Suicide; Tryptophan; Tryptophan Oxygenase | 2008 |
NO scavenging by 3-hydroxyanthranilic acid and 3-hydroxykynurenine: N-nitrosation leads via oxadiazoles to o-quinone diazides.
Topics: 3-Hydroxyanthranilic Acid; Acetylcysteine; Aminophenols; Chromatography, Thin Layer; Diazonium Compounds; Free Radical Scavengers; Hydrazines; Inflammation; Kynurenine; Magnetic Resonance Imaging; Mass Spectrometry; Nitric Oxide; Nitrites; Nitrosation; Nuclear Magnetic Resonance, Biomolecular; ortho-Aminobenzoates; Oxadiazoles; Quinones; Tryptophan | 2008 |
Suppression of T-cell response and prolongation of allograft survival in a rat model by tryptophan catabolites.
Topics: 3-Hydroxyanthranilic Acid; Animals; Bone Marrow; Cell Proliferation; Dendritic Cells; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Rats; T-Lymphocytes; Transplantation Tolerance; Tryptophan | 2009 |
The kynurenine pathway in adolescent depression: preliminary findings from a proton MR spectroscopy study.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Aspartic Acid; Brain; Brain Mapping; Choline; Depression; Female; Humans; Kynurenine; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neural Pathways; Psychiatric Status Rating Scales; Statistics, Nonparametric; Tryptophan; Young Adult | 2010 |
The possible role of the kynurenine pathway in adolescent depression with melancholic features.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Child; Cytokines; Depressive Disorder; Depressive Disorder, Major; Enzyme Induction; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Kynurenine; Male; Neurotoxins; Reference Values; Tryptophan; Young Adult | 2010 |
Insights into therapy: tryptophan oxidation and HIV infection.
Topics: 3-Hydroxyanthranilic Acid; Anti-Inflammatory Agents; Antiviral Agents; Dendritic Cells; Disease Progression; Enzyme Inhibitors; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Inflammation Mediators; Interleukin-17; Kynurenine; Oxidation-Reduction; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Tryptophan; Viral Load | 2010 |
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.
Topics: 3-Hydroxyanthranilic Acid; Biopsy; CD4 Lymphocyte Count; CD4-CD8 Ratio; Cells, Cultured; Colon, Sigmoid; Dendritic Cells; Disease Progression; HIV Infections; HIV Seropositivity; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Inflammation Mediators; Interferon-gamma; Interleukin-17; Kynurenine; Lipopolysaccharides; Lymph Nodes; Prospective Studies; Rectum; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Time Factors; Tryptophan; Up-Regulation; Viral Load | 2010 |
The role of tryptophan catabolism along the kynurenine pathway in acute ischemic stroke.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aged, 80 and over; Brain Ischemia; Free Radical Scavengers; Humans; Inflammation; Kynurenine; Male; Stroke; Tryptophan | 2010 |
Tryptophan metabolite 3-hydroxyanthranilic acid selectively induces activated T cell death via intracellular GSH depletion.
Topics: 3-Hydroxyanthranilic Acid; Animals; Bone Marrow Transplantation; Cell Death; Enterotoxins; Female; Glutathione; Graft vs Host Disease; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymphocyte Activation; Mice; Mice, Inbred C57BL; T-Lymphocytes; Transplantation, Homologous; Tryptophan | 2010 |
Development and validation of a single analytical method for the determination of tryptophan, and its kynurenine metabolites in rat plasma.
Topics: 3-Hydroxyanthranilic Acid; Animals; Charcoal; Chromatography, High Pressure Liquid; Depression; Kynurenic Acid; Kynurenine; Linear Models; Male; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Schizophrenia; Social Isolation; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptophan | 2012 |
Systemic metabolism of tryptophan and its catabolites, kynurenine and 3-HAA, in mice with inflammatory arthritis.
Topics: 3-Hydroxyanthranilic Acid; Animals; Arthritis, Experimental; Catalysis; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Liver; Male; Mice; Tryptophan | 2013 |
An exploratory study of the interplay between decreased concentration of tryptophan, accumulation of kynurenines, and inflammatory arthritis.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Arthritis, Experimental; Gene Expression Regulation; Hydrolases; Inflammation; Kynurenine; Kynurenine 3-Monooxygenase; Lymph Nodes; Mice; Mice, Inbred DBA; Organ Specificity; ortho-Aminobenzoates; RNA, Messenger; Signal Transduction; Spleen; Tryptophan | 2012 |
Increased conversion of tryptophan to nicotinamide in rats by dietary valproate.
Topics: 3-Hydroxyanthranilic Acid; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Food, Formulated; Liver; Male; Niacinamide; Quinolinic Acid; Rats; Rats, Wistar; Tryptophan; Valproic Acid | 2013 |
A community-based study on determinants of circulating markers of cellular immune activation and kynurenines: the Hordaland Health Study.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aging; Biomarkers; Body Mass Index; Creatinine; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Male; Middle Aged; Motor Activity; Neopterin; Norway; ortho-Aminobenzoates; Reference Values; Smoking; Tryptophan; Xanthurenates | 2013 |
The niacin required for optimum growth can be synthesized from L-tryptophan in growing mice lacking tryptophan-2,3-dioxygenase.
Topics: 3-Hydroxyanthranilic Acid; Animals; Body Weight; Diet; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Niacin; Niacinamide; Quinolinic Acid; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 2013 |
The tryptophan metabolite 3-hydroxyanthranilic acid suppresses T cell responses by inhibiting dendritic cell activation.
Topics: 3-Hydroxyanthranilic Acid; Animals; Bone Marrow Cells; Cells, Cultured; Cytokines; Dendritic Cells; Immunologic Factors; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Spleen; T-Lymphocytes; Tryptophan | 2013 |
Suppression of experimental autoimmune glomerulonephritis by tryptophan.
Topics: 3-Hydroxyanthranilic Acid; Animals; Anti-Glomerular Basement Membrane Disease; Apoptosis; CD4-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Free Radical Scavengers; Glomerular Filtration Rate; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Macrophages; Proteinuria; Rats; Rats, Inbred WKY; Th1 Cells; Th2 Cells; Tryptophan | 2014 |
Early activation of the kynurenine pathway predicts early death and long-term outcome in patients resuscitated from out-of-hospital cardiac arrest.
Topics: 3-Hydroxyanthranilic Acid; Aged; Arterial Pressure; Cardiopulmonary Resuscitation; Chromatography, Liquid; Female; Humans; Kynurenic Acid; Kynurenine; Logistic Models; Male; Mass Spectrometry; Middle Aged; Out-of-Hospital Cardiac Arrest; Prognosis; Prospective Studies; Shock, Cardiogenic; Tryptophan | 2014 |
Vitamin B1 deficiency inhibits the increased conversion of tryptophan to nicotinamide in severe food-restricted rats.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Food Deprivation; Liver; Male; Niacin; Niacinamide; Protein Biosynthesis; Rats; Rats, Wistar; Thiamine; Tryptophan; Vitamin B Deficiency | 2015 |
The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats.
Topics: 3-Hydroxyanthranilic Acid; Amino Acid Metabolism, Inborn Errors; Animals; Diet; Hydrolases; Kynurenine; Male; Rats, Wistar; Tryptophan; Weight Gain | 2014 |
Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Arginine; Biomarkers; Dietary Supplements; Female; Healthy Volunteers; Humans; Kynurenic Acid; Kynurenine; Life Style; Male; Methionine; ortho-Aminobenzoates; Pyridoxal Phosphate; Sex Factors; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Xanthurenates; Young Adult | 2015 |
Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Male; Metformin; Middle Aged; Prediabetic State; Pyridoxal Phosphate; Stress, Physiological; Tryptophan; Tryptophan Oxygenase; Xanthurenates | 2015 |
Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users.
Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Carbon; Contraceptives, Oral; Cystathionine; Dietary Supplements; Female; Glycine; Homocysteine; Humans; Kynurenine; Leucine; Methionine; Methylamines; Multivariate Analysis; Pyridoxal Phosphate; Pyridoxine; Serine; Tryptophan; Vitamin B 6 Deficiency; Young Adult | 2015 |
Elevation of Kynurenine Metabolites in Rat Liver and Serum: A Potential Additional Mechanism of the Alcohol Aversive and Anti-cancer Effects of Disulfiram?
Topics: 3-Hydroxyanthranilic Acid; Alcohol Deterrents; Animals; Chromatography, High Pressure Liquid; Disulfiram; Hydrolases; Kynurenine; Kynurenine 3-Monooxygenase; Liver; Male; Rats; Rats, Wistar; Transaminases; Tryptophan | 2016 |
Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease.
Topics: 3-Hydroxyanthranilic Acid; Aged; Animals; Biomarkers; Body Mass Index; Cholesterol; Coronary Artery Disease; Cross-Sectional Studies; Energy Intake; Fatty Acids, Omega-3; Female; Fishes; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Neopterin; Norway; Nutrition Assessment; ortho-Aminobenzoates; Seafood; Triglycerides; Tryptophan; Xanthurenates | 2017 |
Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.
Topics: 3-Hydroxyanthranilic Acid; Adolescent; Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cross-Sectional Studies; Female; Humans; Inflammation; Interleukin-10; Kynurenine; Linear Models; Male; Neopterin; ortho-Aminobenzoates; Pyridoxal Phosphate; Surveys and Questionnaires; Tryptophan; Vitamin B 6; Young Adult | 2016 |
Kynurenine Pathway Metabolites in Alzheimer's Disease.
Topics: 3-Hydroxyanthranilic Acid; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cognition Disorders; Cohort Studies; Female; Humans; Kynurenine; Male; Middle Aged; Neuropsychological Tests; Quinolinic Acid; Signal Transduction; Statistics, Nonparametric; Tryptophan; Xanthurenates | 2017 |
Ultra-performance liquid chromatography-tandem mass spectrometry quantitative profiling of tryptophan metabolites in human plasma and its application to clinical study.
Topics: 3-Hydroxyanthranilic Acid; Adult; Chromatography, High Pressure Liquid; Female; Humans; Kynurenic Acid; Linear Models; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tryptophan | 2019 |
Peripheral tryptophan, serotonin, kynurenine, and their metabolites in major depression: A case-control study.
Topics: 3-Hydroxyanthranilic Acid; Adult; Case-Control Studies; Cohort Studies; Depressive Disorder, Major; Female; Humans; Kynurenine; Male; Middle Aged; Niacinamide; Picolinic Acids; Serotonin; Tryptophan; Xanthurenates | 2020 |
Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy.
Topics: 3-Hydroxyanthranilic Acid; Affect; Case-Control Studies; Electroconvulsive Therapy; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Picolinic Acids; Quinolinic Acid; Tryptophan; Xanthurenates | 2020 |
Comprehensive assessment of multiple tryptophan metabolites as potential biomarkers for immune checkpoint inhibitors in patients with non-small cell lung cancer.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Aged, 80 and over; B7-H1 Antigen; Biomarkers; Carcinoma, Non-Small-Cell Lung; Female; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Male; Middle Aged; Progression-Free Survival; Prospective Studies; Regression Analysis; ROC Curve; Sensitivity and Specificity; Treatment Outcome; Tryptophan; Xanthurenates | 2021 |
Indoleamine 2,3-dioxygenase (IDO)-1 and IDO-2 activity and severe course of COVID-19.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Apoptosis; Autopsy; Brain; COVID-19; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung; Middle Aged; Myocardium; Prospective Studies; Quinolinic Acid; Severity of Illness Index; Tryptophan | 2022 |
Establishment of an early diagnosis model of colon cancerous bowel obstruction based on 1H NMR.
Topics: 3-Hydroxyanthranilic Acid; Biomarkers; Colon; Early Diagnosis; Humans; Kynurenic Acid; Metabolome; Metabolomics; Phenylalanine; Proton Magnetic Resonance Spectroscopy; Tryptophan; Tyrosine | 2022 |
Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids.
Topics: 3-Hydroxyanthranilic Acid; Adrenal Cortex Hormones; Animals; Biomarkers; Chromatography, Liquid; Epilepsy; Kynurenic Acid; Kynurenine; Male; Quinolinic Acid; Spasm; Tandem Mass Spectrometry; Tryptophan | 2022 |