tryptoline has been researched along with yohimbine in 6 studies
| Studies (tryptoline) | Trials (tryptoline) | Recent Studies (post-2010) (tryptoline) | Studies (yohimbine) | Trials (yohimbine) | Recent Studies (post-2010) (yohimbine) |
|---|---|---|---|---|---|
| 222 | 1 | 69 | 5,893 | 253 | 532 |
| Protein | Taxonomy | tryptoline (IC50) | yohimbine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 1.02 | |
| D(2) dopamine receptor | Homo sapiens (human) | 2.06 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0428 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0466 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.126 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0682 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.013 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.126 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.074 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 1.3 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 1.689 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Audia, JE; Cohen, ML; Droste, JJ; Evrard, DA; Fludzinski, P; Lucaites, VL; Murdoch, GR; Nelson, DL; Nissen, JS; Schenck, KW | 1 |
| Andrade, RB; Bougie, D; Boxer, MB; Brimacombe, KR; Brown, LE; Brown, MK; Burns, NZ; Cha, JK; Cheff, DM; Cheng, K; Clardy, J; Clement, JA; Coussens, NP; Crooks, PA; Cuny, GD; Dillon, C; Dorjsuren, D; Eastman, RT; Ganor, J; Garg, NK; Goess, BC; Grossman, RB; Guha, R; Hall, MD; Henderson, MJ; Huang, R; Hughes, CC; Iannotti, MJ; Inglese, J; Itkin, Z; Jadhav, A; Johnston, JN; Joullie, MM; Karavadhi, S; Kearney, SE; Kinghorn, AD; Kingston, DGI; Klumpp-Thomas, C; Krische, MJ; Kwon, O; Lee, TD; Lynch, C; Maimone, TJ; Majumdar, S; Maloney, KN; Mevers, EE; Michael, S; Mohamed, E; Moreno, J; Morrill, LA; Murphy, BT; Nagorny, P; Olson, DE; Overman, LE; Picazo, E; Porco, JA; Ren, T; Rivas, F; Rohde, JM; Ross, SA; Roth, JS; Sakamuru, S; Sarpong, R; Sharma, I; Shaw, JT; Shen, B; Shen, M; Shi, W; Shinn, P; Simeonov, A; Snyder, JK; Stephenson, CRJ; Sun, W; Susick, RB; Tan, DS; Tang, Y; Taylor, RE; Thomson, RJ; Titus, SA; Verano, AL; Vosburg, DA; Wan, KK; Wu, J; Wuest, WM; Xia, M; Xu, Z; Yasgar, A; Zahoránszky-Kőhalmi, G; Zakarian, A; Zhang, Y; Zhang, YQ; Zhao, J; Zhao, T; Zheng, W; Zuo, Z | 1 |
| Schechter, MD | 1 |
| Fang, L; Lin, Q; Ren, Y; Zou, X | 1 |
| Bains, JS; Kuzmiski, JB; Pittman, QJ | 1 |
| Arnold, AC; Dang, LH; Huigens, RW; Luesch, H; Matthews, JH; Norwood, VM; Paciaroni, NG; Ratnayake, R | 1 |
6 other study(ies) available for tryptoline and yohimbine
| Article | Year |
|---|---|
Potent, selective tetrahydro-beta-carboline antagonists of the serotonin 2B (5HT2B) contractile receptor in the rat stomach fundus.
Topics: Animals; Carbolines; Cell Line; Cricetinae; Gastric Fundus; In Vitro Techniques; Male; Mesocricetus; Mice; Molecular Structure; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Yohimbine | 1996 |
Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.
Topics: | 2018 |
Serotonergic mediation of tetrahydro-beta-carboline.
Topics: Animals; Carbolines; Discrimination Learning; Dose-Response Relationship, Drug; Fenfluramine; Lysergic Acid Diethylamide; Male; Rats; Rats, Inbred Strains; Serotonin; Yohimbine | 1986 |
Sympathetic modulation of activity in Adelta- and C-primary nociceptive afferents after intradermal injection of capsaicin in rats.
Topics: Action Potentials; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Capsaicin; Carbolines; Injections, Intradermal; Male; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neurons, Afferent; Nociceptors; Physical Stimulation; Prazosin; Rats; Rats, Sprague-Dawley; Sympathectomy; Vasoconstrictor Agents; Vasopressins; Yohimbine | 2005 |
Metaplasticity of hypothalamic synapses following in vivo challenge.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Biophysics; Carbolines; Clonidine; Down-Regulation; Drug Interactions; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Glutamic Acid; Guanosine Diphosphate; Hypothalamus; In Vitro Techniques; Intracranial Hemorrhages; Long-Term Synaptic Depression; Male; Microinjections; Neurons; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Synapses; Thionucleotides; Yohimbine | 2009 |
A Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine.
Topics: Animals; Biological Products; Carbolines; Cell Survival; HCT116 Cells; Humans; Indole Alkaloids; Mice; Molecular Conformation; RAW 264.7 Cells; Small Molecule Libraries; Stereoisomerism; Yohimbine | 2017 |