Page last updated: 2024-09-02

tryptoline and streptonigrin

tryptoline has been researched along with streptonigrin in 3 studies

Compound Research Comparison

Studies
(tryptoline)
Trials
(tryptoline)
Recent Studies (post-2010)
(tryptoline)
Studies
(streptonigrin)
Trials
(streptonigrin)
Recent Studies (post-2010) (streptonigrin)
222169399748

Protein Interaction Comparison

ProteinTaxonomytryptoline (IC50)streptonigrin (IC50)
protein-arginine deiminase type-4Homo sapiens (human)2.5
VifHuman immunodeficiency virus 110.82
TatHuman immunodeficiency virus 142.129
DNA dC->dU-editing enzyme APOBEC-3G isoform 1Homo sapiens (human)10.82
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)1.87
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)1.87
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)1.87
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)1.87
Sentrin-specific protease 6Homo sapiens (human)5.2
Sentrin-specific protease 2Homo sapiens (human)6.9
Sentrin-specific protease 1Homo sapiens (human)0.52
Protein-arginine deiminase type-3Homo sapiens (human)0.43
Protein-arginine deiminase type-4Homo sapiens (human)2.5

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Deng, Z; Huang, T; Kong, D; Lin, S; Wang, X1

Other Studies

3 other study(ies) available for tryptoline and streptonigrin

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
StnK2 catalysing a Pictet-Spengler reaction involved in the biosynthesis of the antitumor reagent streptonigrin.
    Organic & biomolecular chemistry, 2018, 12-05, Volume: 16, Issue:47

    Topics: Antibiotics, Antineoplastic; Biosynthetic Pathways; Carbolines; Stereoisomerism; Streptomyces; Streptonigrin; Substrate Specificity; Tryptophan

2018