Page last updated: 2024-09-02

tryptoline and harmaline

tryptoline has been researched along with harmaline in 11 studies

Compound Research Comparison

Studies
(tryptoline)
Trials
(tryptoline)
Recent Studies (post-2010)
(tryptoline)
Studies
(harmaline)
Trials
(harmaline)
Recent Studies (post-2010) (harmaline)
2221696332125

Protein Interaction Comparison

ProteinTaxonomytryptoline (IC50)harmaline (IC50)
AcetylcholinesteraseElectrophorus electricus (electric eel)4.9
Amine oxidase [flavin-containing] A Rattus norvegicus (Norway rat)0.012
Amine oxidase [flavin-containing] AHomo sapiens (human)0.0329

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's6 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dukat, M; Glennon, RA; Grella, B; Herrick-Davis, K; Khorana, N; Purohit, A; Smith, C; Teitler, M1
Changwichit, K; Ingkaninan, K; Khorana, N; Utsintong, M1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Andrade, RB; Bougie, D; Boxer, MB; Brimacombe, KR; Brown, LE; Brown, MK; Burns, NZ; Cha, JK; Cheff, DM; Cheng, K; Clardy, J; Clement, JA; Coussens, NP; Crooks, PA; Cuny, GD; Dillon, C; Dorjsuren, D; Eastman, RT; Ganor, J; Garg, NK; Goess, BC; Grossman, RB; Guha, R; Hall, MD; Henderson, MJ; Huang, R; Hughes, CC; Iannotti, MJ; Inglese, J; Itkin, Z; Jadhav, A; Johnston, JN; Joullie, MM; Karavadhi, S; Kearney, SE; Kinghorn, AD; Kingston, DGI; Klumpp-Thomas, C; Krische, MJ; Kwon, O; Lee, TD; Lynch, C; Maimone, TJ; Majumdar, S; Maloney, KN; Mevers, EE; Michael, S; Mohamed, E; Moreno, J; Morrill, LA; Murphy, BT; Nagorny, P; Olson, DE; Overman, LE; Picazo, E; Porco, JA; Ren, T; Rivas, F; Rohde, JM; Ross, SA; Roth, JS; Sakamuru, S; Sarpong, R; Sharma, I; Shaw, JT; Shen, B; Shen, M; Shi, W; Shinn, P; Simeonov, A; Snyder, JK; Stephenson, CRJ; Sun, W; Susick, RB; Tan, DS; Tang, Y; Taylor, RE; Thomson, RJ; Titus, SA; Verano, AL; Vosburg, DA; Wan, KK; Wu, J; Wuest, WM; Xia, M; Xu, Z; Yasgar, A; Zahoránszky-Kőhalmi, G; Zakarian, A; Zhang, Y; Zhang, YQ; Zhao, J; Zhao, T; Zheng, W; Zuo, Z1
Bourke, CA; Carrigan, MJ; Dixon, RJ1
Baumgarten, HG; Brüning, G; Kaulen, P; Rommelspacher, H1
Oderfeld-Nowak, B; Rommelspacher, H; Skup, M1
Airaksinen, MM; Kari, I1
Bonsaii, M; Khalilzadeh, MA; Maali, P; Manouchehri, F; Nafisi, S1
Khalilzadeh, MA; Malekabady, ZM; Nafisi, S1
Cabrerizo, FM; Denofrio, MP; Erra-Balsells, R; García Einschlag, FS; Rasse-Suriani, FAO; Schmidt De León, T; Villarruel, F1

Reviews

1 review(s) available for tryptoline and harmaline

ArticleYear
Beta-carbolines, psychoactive compounds in the mammalian body. Part I: Occurrence, origin and metabolism.
    Medical biology, 1981, Volume: 59, Issue:1

    Topics: Animals; Carbolines; Chemical Phenomena; Chemistry; Ethanol; Food; Harmaline; Humans; Indoles; Nicotiana; Plants; Plants, Toxic; Tetrahydrofolates; Tissue Distribution

1981

Other Studies

10 other study(ies) available for tryptoline and harmaline

ArticleYear
Binding of tetrahydrocarboline derivatives at human 5-HT5A receptors.
    Journal of medicinal chemistry, 2003, Aug-28, Volume: 46, Issue:18

    Topics: Animals; Binding, Competitive; Carbolines; Cell Line; Humans; Mice; Radioligand Assay; Rats; Receptors, Serotonin; Structure-Activity Relationship

2003
Prospective acetylcholinesterase inhibitory activity of indole and its analogs.
    Bioorganic & medicinal chemistry letters, 2012, Apr-15, Volume: 22, Issue:8

    Topics: Acetylcholinesterase; Binding Sites; Carbolines; Cholinesterase Inhibitors; Enzyme Activation; Humans; Indoles; Molecular Conformation; Quinolines

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.
    ACS central science, 2018, Dec-26, Volume: 4, Issue:12

    Topics:

2018
Upper motor neurone effects in sheep of some beta-carboline alkaloids identified in zygophyllaceous plants.
    Australian veterinary journal, 1990, Volume: 67, Issue:7

    Topics: Alkaloids; Animals; Carbolines; Female; Harmaline; Harmine; Locomotion; Motor Neurons; Plants, Toxic; Sheep

1990
Characterization and quantitative autoradiography of [3H]tryptamine binding sites in rat brain.
    Brain research, 1986, Feb-26, Volume: 366, Issue:1-2

    Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Carbolines; Harmaline; Male; Metergoline; Methysergide; Rats; Rats, Inbred Strains; Serotonin; Tryptamines

1986
In vitro studies on the effect of beta-carbolines on the activities of acetylcholinesterase and choline acetyltransferase and on the muscarinic receptor binding of the rat brain.
    Journal of neurochemistry, 1983, Volume: 41, Issue:1

    Topics: Acetylcholinesterase; Alkaloids; Animals; Brain; Carbolines; Cattle; Choline O-Acetyltransferase; Erythrocytes; Harmaline; Harmine; Indoles; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic; Structure-Activity Relationship

1983
Beta-carboline alkaloids bind DNA.
    Journal of photochemistry and photobiology. B, Biology, 2010, Aug-02, Volume: 100, Issue:2

    Topics: Animals; Antineoplastic Agents; Binding Sites; Carbolines; Cattle; DNA; Harmaline; Harmine; Intercalating Agents; Nucleic Acid Conformation; Peganum; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared

2010
Interaction of β-carboline alkaloids with RNA.
    DNA and cell biology, 2010, Volume: 29, Issue:12

    Topics: Carbolines; Harmaline; Harmine; Nucleic Acid Conformation; Peganum; Plants, Medicinal; RNA, Fungal

2010
Light-induced full aromatization and hydroxylation of 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole alkaloid: Oxygen partial pressure as a key modulator of the photoproducts distribution.
    Journal of photochemistry and photobiology. B, Biology, 2019, Volume: 199

    Topics: Alkaloids; Carbolines; Harmaline; Harmine; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxylation; Indoles; Light; Multivariate Analysis; Oxygen; Partial Pressure; Photochemical Processes; Reactive Oxygen Species; Singlet Oxygen; Structure-Activity Relationship

2019