Page last updated: 2024-09-02

tryptoline and dihydroergocristine monomesylate

tryptoline has been researched along with dihydroergocristine monomesylate in 3 studies

Compound Research Comparison

Studies
(tryptoline)
Trials
(tryptoline)
Recent Studies (post-2010)
(tryptoline)
Studies
(dihydroergocristine monomesylate)
Trials
(dihydroergocristine monomesylate)
Recent Studies (post-2010) (dihydroergocristine monomesylate)
2221691304

Protein Interaction Comparison

ProteinTaxonomytryptoline (IC50)dihydroergocristine monomesylate (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.239
Cytochrome P450 3A4Homo sapiens (human)3
Alpha-2A adrenergic receptorHomo sapiens (human)0.002
Cytochrome P450 2C9 Homo sapiens (human)3
Beta-3 adrenergic receptorHomo sapiens (human)3.308
D(2) dopamine receptorHomo sapiens (human)0.0015
Alpha-2B adrenergic receptorHomo sapiens (human)0.0079
Alpha-2C adrenergic receptorHomo sapiens (human)0.0087
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0007
D(1A) dopamine receptorHomo sapiens (human)1.179
Alpha-1D adrenergic receptorHomo sapiens (human)0.0074
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.015
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.239
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.0007
Cytochrome P450 2C19Homo sapiens (human)3
Mu-type opioid receptorHomo sapiens (human)0.85
D(3) dopamine receptorHomo sapiens (human)0.0023
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0066
5-hydroxytryptamine receptor 6Homo sapiens (human)0.042

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Fallarero, A; Hanski, L; Isojärvi, J; Karhu, E; Vuorela, P1

Other Studies

3 other study(ies) available for tryptoline and dihydroergocristine monomesylate

ArticleYear
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy.
    Journal of natural products, 2017, 10-27, Volume: 80, Issue:10

    Topics: Anti-Bacterial Agents; Azithromycin; Biological Products; Cell Line; Cell Survival; Chlamydophila pneumoniae; Drug Discovery; Humans; Ligands; Microbial Sensitivity Tests; Molecular Structure

2017