tryptamine-4,5-dione has been researched along with mocetinostat in 2 studies
| Studies (tryptamine-4,5-dione) | Trials (tryptamine-4,5-dione) | Recent Studies (post-2010) (tryptamine-4,5-dione) | Studies (mocetinostat) | Trials (mocetinostat) | Recent Studies (post-2010) (mocetinostat) |
|---|---|---|---|---|---|
| 17 | 0 | 4 | 21,735 | 390 | 8,606 |
| Protein | Taxonomy | tryptamine-4,5-dione (IC50) | mocetinostat (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 0.7851 | |
| Nuclear receptor corepressor 1 | Homo sapiens (human) | 0.022 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.57 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.102 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.102 | |
| Histone deacetylase 4 | Homo sapiens (human) | 0.5717 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.3433 | |
| Histone deacetylase 7 | Homo sapiens (human) | 0.6725 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.3537 | |
| Histone deacetylase 11 | Homo sapiens (human) | 0.6386 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.6725 | |
| Histone deacetylase 6 | Homo sapiens (human) | 0.5717 | |
| Histone deacetylase 5 | Homo sapiens (human) | 0.6725 | |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | 0.045 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kato, Y; Kettle, AJ; Maghzal, GJ; Turner, R; Winterbourn, CC; Ximenes, VF | 1 |
| Dickerhof, N; Harwood, DT; Kato, Y; Kettle, AJ; Peskin, AV | 1 |
2 other study(ies) available for tryptamine-4,5-dione and mocetinostat
| Article | Year |
|---|---|
Serotonin as a physiological substrate for myeloperoxidase and its superoxide-dependent oxidation to cytotoxic tryptamine-4,5-dione.
Topics: Catalysis; Chromatography, High Pressure Liquid; Cytotoxins; Dimerization; Enzyme Inhibitors; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hypochlorous Acid; Indolequinones; Mass Spectrometry; Neutrophils; Oxidation-Reduction; Peroxidase; Serotonin; Substrate Specificity; Superoxides; Tryptamines | 2009 |
Myeloperoxidase catalyzes the conjugation of serotonin to thiols via free radicals and tryptamine-4,5-dione.
Topics: Biocatalysis; Free Radicals; Humans; Indolequinones; Oxidation-Reduction; Peroxidase; Serotonin; Sulfhydryl Compounds; Time Factors; Tryptamines | 2012 |