trypanothione has been researched along with eflornithine in 7 studies
| Studies (trypanothione) | Trials (trypanothione) | Recent Studies (post-2010) (trypanothione) | Studies (eflornithine) | Trials (eflornithine) | Recent Studies (post-2010) (eflornithine) |
|---|---|---|---|---|---|
| 187 | 0 | 47 | 2,377 | 93 | 268 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Fairlamb, AH; Hunter, KJ; Strobos, CA | 1 |
| Bacchi, CJ; Cerami, A; Fairlamb, AH; Henderson, GB | 1 |
| Ariyanayagam, MR; Davies, AJ; Hunter, KJ; Mastri, C; Thorborn, DE | 1 |
| Araki, N; Asakura, M; Kozaki, S; Nishimura, K; Ohnishi, Y; Samosomsuk, W; Shima, K; Yamasaki, S; Yanase, T | 1 |
| Heby, O; Persson, L; Rentala, M | 1 |
| Madhubala, R; Roberts, S; Singh, AK; Ullman, B | 1 |
| Bogacz, M; Dick, TP; Ebersoll, S; Günter, LM; Krauth-Siegel, RL | 1 |
1 review(s) available for trypanothione and eflornithine
| Article | Year |
|---|---|
Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis.
Topics: Adenosine; Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Chagas Disease; Eflornithine; Enzyme Inhibitors; Glutathione; Humans; Leishmania; Leishmaniasis; Ornithine Decarboxylase Inhibitors; Robenidine; Spermidine; Spermidine Synthase; Trypanocidal Agents; Trypanosoma brucei gambiense; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Trypanosomiasis, African | 2007 |
6 other study(ies) available for trypanothione and eflornithine
| Article | Year |
|---|---|
The interaction of trypanocidal drugs with polyamine and trypanothione metabolism.
Topics: Animals; Arginine; Carboxy-Lyases; Crithidia; Eflornithine; Glutathione; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine; Trypanocidal Agents | 1990 |
In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma brucei.
Topics: Animals; Chromatography, High Pressure Liquid; Eflornithine; Glutathione; Male; Polyamines; Rats; Rats, Inbred Strains; Spermidine; Sulfhydryl Compounds; Trypanosoma brucei brucei | 1987 |
Polyamine and thiol metabolism in Trypanosoma granulosum: similarities with Trypanosoma cruzi.
Topics: Animals; Biogenic Polyamines; Cadaverine; Culture Media; Eflornithine; Glutathione; Methylhistidines; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Sulfhydryl Compounds; Tritium; Trypanosoma; Trypanosoma cruzi | 2001 |
Effects of polyamines on two strains of Trypanosoma brucei in infected rats and in vitro culture.
Topics: Amide Synthases; Animals; Culture Media; Eflornithine; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione; Hematocrit; Hydrogen Peroxide; Male; NADH, NADPH Oxidoreductases; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Oxidative Stress; Polyamines; Putrescine; Rats; Rats, Wistar; RNA, Messenger; Spermidine; Spermine; Trypanosoma brucei brucei; Trypanosomiasis, African | 2006 |
A quantitative proteomic screen to identify potential drug resistance mechanism in α-difluoromethylornithine (DFMO) resistant Leishmania donovani.
Topics: Biomarkers; Chromatography, Liquid; Drug Resistance; Eflornithine; Free Radicals; Glutathione; GTP Phosphohydrolases; Leishmania donovani; Mass Spectrometry; Ornithine Decarboxylase; Peptides; Polyamines; Protein Folding; Proteomics; Signal Transduction; Spermidine; Subcellular Fractions | 2014 |
A tryparedoxin-coupled biosensor reveals a mitochondrial trypanothione metabolism in trypanosomes.
Topics: Biosensing Techniques; Eflornithine; Glutathione; Green Fluorescent Proteins; Homeostasis; Hydrogen Peroxide; Mitochondria; Oxidation-Reduction; Oxidative Stress; Spermidine; Thioredoxins; Trypanocidal Agents; Trypanosoma brucei brucei | 2020 |