Compounds > trypanothione

Page last updated: 2024-09-03

trypanothione and cysteine

trypanothione has been researched along with cysteine in 12 studies

Compound Research Comparison

Studies (trypanothione)	Trials (trypanothione)	Recent Studies (post-2010) (trypanothione)	Studies (cysteine)	Trials (cysteine)	Recent Studies (post-2010) (cysteine)
187	0	47	40,132	418	11,457

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (8.33)	18.2507
2000's	10 (83.33)	29.6817
2010's	1 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dey, S; Gage, D; Lightbody, J; Mukhopadhyay, R; Ouellette, M; Rosen, BP; Xu, N	1
Bruns, K; Budde, H; Flohé, L; Guerrero, SA; Hecht, HJ; Hofmann, B; Kalisz, HM; Menge, U; Montemartini, M; Nogoceke, E; Steinert, P; Wissing, JB	1
Brochu, C; Demicheli, C; Ferreira, Cdos S; Frézard, F; Martins, PS; Ouellette, M	1
Alphey, MS; Bond, CS; Fairlamb, AH; Gabrielsen, M; Hunter, WN; Leonard, GA; McSweeney, SM; Micossi, E; Ravelli, RB; Tetaud, E	1
Ding, K; Li, F; Sun, H; Yan, S	1
Krauth-Siegel, RL; Schmidt, H	1
Budde, H; Flohé, L; Piñeyro, MD; Radi, R; Robello, C; Stehr, M; Trujillo, M	1
El Fadili, K; Guimond, C; Légaré, D; Leprohon, P; Messier, N; Ouellette, M; Papadopoulou, B; Roy, G; Saravia, NG; Trudel, N	1
Hernández, E; Hurtado, G; Iturbe, A; Ondarza, RN; Tamayo, E	1
Dirdjaja, N; Krauth-Siegel, RL; Melchers, J; Ruppert, T	1
Coombs, GH; Westrop, GD; Williams, RA	1
Fairlamb, AH; König, J; Stevens, MF; Wells, G; Wyatt, PG; Wyllie, S	1

Other Studies

12 other study(ies) available for trypanothione and cysteine

Article	Year
Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania. Proceedings of the National Academy of Sciences of the United States of America, 1996, Sep-17, Volume: 93, Issue:19 Topics: Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Arsenic Poisoning; Chromatography, High Pressure Liquid; Cysteine; Drug Resistance; Glutathione; Leishmania; Models, Biological; Mutation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spermidine	1996
Structures of tryparedoxins revealing interaction with trypanothione. Biological chemistry, 2001, Volume: 382, Issue:3 Topics: Amino Acid Sequence; Animals; Catalytic Domain; Crithidia fasciculata; Crystallography, X-Ray; Cysteine; Glutathione; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Sequence Homology, Amino Acid; Serine; Spermidine; Thioredoxins	2001
Thiol-induced reduction of antimony(V) into antimony(III): a comparative study with trypanothione, cysteinyl-glycine, cysteine and glutathione. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2003, Volume: 16, Issue:3 Topics: Antimony; Cysteine; Dipeptides; Glutathione; Hydrogen-Ion Concentration; Kinetics; Meglumine; Organometallic Compounds; Oxidation-Reduction; Spermidine; Sulfhydryl Compounds; Time Factors	2003
Tryparedoxins from Crithidia fasciculata and Trypanosoma brucei: photoreduction of the redox disulfide using synchrotron radiation and evidence for a conformational switch implicated in function. The Journal of biological chemistry, 2003, Jul-11, Volume: 278, Issue:28 Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Chloroplasts; Cloning, Molecular; Crithidia fasciculata; Cysteine; Disulfides; Escherichia coli; Fructose-Bisphosphatase; Glutathione; Light; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutation; Neoplasm Proteins; Oxidation-Reduction; Peroxidases; Peroxiredoxins; Protein Conformation; Protein Isoforms; Protein Structure, Secondary; Recombinant Proteins; Sequence Homology, Amino Acid; Spermidine; Synchrotrons; Thioredoxins; Time Factors; Trypanosoma brucei brucei; Tryptophan	2003
Reduction of pentavalent antimony by trypanothione and formation of a binary and ternary complex of antimony(III) and trypanothione. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2003, Volume: 8, Issue:6 Topics: Antimony; Antiprotozoal Agents; Chromatography, High Pressure Liquid; Cysteine; Dithiothreitol; Glutathione; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spermidine	2003
Functional and physicochemical characterization of the thioredoxin system in Trypanosoma brucei. The Journal of biological chemistry, 2003, Nov-21, Volume: 278, Issue:47 Topics: Animals; Catalysis; Cysteine; Electrochemistry; Glutathione; Hydrogen-Ion Concentration; Oxidation-Reduction; Protozoan Proteins; Spermidine; Thioredoxins; Trypanosoma brucei brucei	2003
Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols. The Journal of biological chemistry, 2004, Aug-13, Volume: 279, Issue:33 Topics: Animals; Catalysis; Cysteine; Cytosol; Dose-Response Relationship, Drug; Electrons; Glutathione; Hydrogen-Ion Concentration; Kinetics; Macrophages; Manganese; Models, Chemical; Oxygen; Peroxidases; Peroxynitrous Acid; Porphyrins; Protozoan Proteins; Spermidine; Sulfhydryl Compounds; Temperature; Time Factors; Trypanosoma brucei brucei; Trypanosoma cruzi	2004
Role of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:5 Topics: Animals; Antimony; Antimony Sodium Gluconate; ATP-Binding Cassette Transporters; Cell Line; Cysteine; DNA, Protozoan; Drug Resistance; Glutathione; Leishmania infantum; Membrane Glycoproteins; Microscopy, Confocal; Monocytes; Oligonucleotide Array Sequence Analysis; Protozoan Proteins; Ribonucleoproteins; Saccharomyces cerevisiae Proteins; Spermidine; Transfection	2005
Naegleria fowleri: a free-living highly pathogenic amoeba contains trypanothione/trypanothione reductase and glutathione/glutathione reductase systems. Experimental parasitology, 2006, Volume: 114, Issue:3 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Glutathione Reductase; NADH, NADPH Oxidoreductases; Naegleria fowleri; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spermidine; Virulence	2006
Glutathionylation of trypanosomal thiol redox proteins. The Journal of biological chemistry, 2007, Mar-23, Volume: 282, Issue:12 Topics: Amino Acid Sequence; Animals; Cysteine; Disulfides; Glutathione; Insulin; Molecular Sequence Data; Oxidation-Reduction; Sequence Homology, Amino Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spermidine; Sulfhydryl Compounds; Trypanosoma	2007
Two pathways for cysteine biosynthesis in Leishmania major. The Biochemical journal, 2009, May-27, Volume: 420, Issue:3 Topics: Amino Acid Sequence; Animals; Biological Transport; Biosynthetic Pathways; Blotting, Western; Catalysis; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Cysteine Synthase; Electrophoresis, Polyacrylamide Gel; Glutathione; Kinetics; Leishmania major; Methionine; Molecular Sequence Data; Protozoan Proteins; Sequence Homology, Amino Acid; Serine; Serine O-Acetyltransferase; Spermidine; Substrate Specificity; Sulfides; Sulfur Radioisotopes	2009
Antitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism. The Journal of biological chemistry, 2011, Mar-11, Volume: 286, Issue:10 Topics: Amide Synthases; Animals; Antineoplastic Agents; Benzothiazoles; Cysteine; Dose-Response Relationship, Drug; Glutathione; Hydroquinones; Protozoan Proteins; Spermidine; Thioredoxins; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis	2011