trypanothione has been researched along with benzonidazole in 6 studies
| Studies (trypanothione) | Trials (trypanothione) | Recent Studies (post-2010) (trypanothione) | Studies (benzonidazole) | Trials (benzonidazole) | Recent Studies (post-2010) (benzonidazole) |
|---|---|---|---|---|---|
| 187 | 0 | 47 | 1,314 | 51 | 775 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agosin, M; Maya, JD; Morello, A; Opazo, E; Repetto, Y | 1 |
| Agosín, M; Gaule, C; Maya, JD; Morello, A; Ojeda, JM; Repetto, Y; Tellez, R | 1 |
| Ferreira, J; Maya, JD; Morello, A; Pabón, A; Pavani, M; Pino, L; Repetto, Y; Rodríguez, A | 1 |
| Alberca, LN; Balcazar, D; Benitez, D; Carrillo, C; Comini, M; Fraccaroli, L; Medeiros, A; Sbaraglini, ML; Talevi, A | 1 |
| Campos-Estrada, C; Castro, L; Cortes, L; Díaz, MV; Kemmerling, U; Lapier, M; López-Muñoz, R; Maya, JD; Miranda, MR; Morello, A; Pereira, CA; Reigada, C; Seguel, V | 1 |
| Encalada, R; González-Chávez, Z; Manning-Cela, R; Márquez-Dueñas, C; Mejia-Tlachi, M; Michels, PAM; Moreno-Sánchez, R; Rodríguez-Enríquez, S; Saavedra, E; Vázquez, C | 1 |
6 other study(ies) available for trypanothione and benzonidazole
| Article | Year |
|---|---|
Glutathione and trypanothione in several strains of Trypanosoma cruzi: effect of drugs.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cycloheximide; Glutathione; Nifurtimox; Nitroimidazoles; Species Specificity; Spermidine; Trypanocidal Agents; Trypanosoma cruzi | 1996 |
Effects of nifurtimox and benznidazole upon glutathione and trypanothione content in epimastigote, trypomastigote and amastigote forms of Trypanosoma cruzi.
Topics: Animals; Glutathione; Nifurtimox; Nitroimidazoles; Spermidine; Sulfhydryl Compounds; Trypanocidal Agents; Trypanosoma cruzi | 1997 |
Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi.
Topics: Animals; Buthionine Sulfoximine; Electrophoresis, Polyacrylamide Gel; Glutathione; Metallothionein; Nifurtimox; Nitroimidazoles; Protozoan Proteins; Spermidine; Time Factors; Trypanocidal Agents; Trypanosoma cruzi | 2004 |
Discovery of novel polyamine analogs with anti-protozoal activity by computer guided drug repositioning.
Topics: Amide Synthases; Antiprotozoal Agents; Chagas Disease; Computer Simulation; Drug Repositioning; Glutathione; Humans; Imidazoles; Nitroimidazoles; Polyamines; Spermidine; Thiophenes; Trypanosoma cruzi; User-Computer Interface | 2016 |
Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about the polyamine transport as an anti-Trypanosoma cruzi target.
Topics: Animals; Chagas Disease; Chlorocebus aethiops; DNA, Protozoan; Dose-Response Relationship, Drug; Glutathione; Macrophages; Male; Mice; Mice, Inbred BALB C; Myocardium; Nitroimidazoles; Parasitemia; Pentamidine; Putrescine; Random Allocation; Spermidine; Thymidine; Trypanocidal Agents; Trypanosoma cruzi; Vero Cells | 2016 |
Gamma-glutamylcysteine synthetase and tryparedoxin 1 exert high control on the antioxidant system in Trypanosoma cruzi contributing to drug resistance and infectivity.
Topics: Amide Synthases; Antioxidants; Buthionine Sulfoximine; Cell Line; Drug Combinations; Drug Resistance; Fibroblasts; Gene Expression Regulation; Glutamate-Cysteine Ligase; Glutathione; Humans; Hydrogen Peroxide; NADH, NADPH Oxidoreductases; Nitroimidazoles; Oxidation-Reduction; Oxidative Stress; Peroxidases; Protozoan Proteins; Signal Transduction; Spermidine; Thioredoxins; Trypanocidal Agents; Trypanosoma cruzi | 2019 |