troxacitabine has been researched along with zidovudine in 3 studies
| Studies (troxacitabine) | Trials (troxacitabine) | Recent Studies (post-2010) (troxacitabine) | Studies (zidovudine) | Trials (zidovudine) | Recent Studies (post-2010) (zidovudine) |
|---|---|---|---|---|---|
| 72 | 17 | 2 | 10,180 | 1,399 | 1,188 |
| Protein | Taxonomy | troxacitabine (IC50) | zidovudine (IC50) |
|---|---|---|---|
| Thymidine kinase, cytosolic | Homo sapiens (human) | 3 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 0.6633 | |
| Protease | Human immunodeficiency virus 1 | 0.015 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beach, JW; Cannon, DL; Chu, CK; Jeong, LS; Kim, HO; Nampalli, S; Schinazi, RF; Shanmuganathan, K | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Cheng, YC; Haggerty, JG; Schwartz, PM | 1 |
3 other study(ies) available for troxacitabine and zidovudine
| Article | Year |
|---|---|
L-beta-(2S,4S)- and L-alpha-(2S,4R)-dioxolanyl nucleosides as potential anti-HIV agents: asymmetric synthesis and structure-activity relationships.
Topics: Antiviral Agents; Cell Line; Cell Survival; Cytosine; Dioxolanes; HIV-1; Humans; Molecular Structure; Purines; Pyrimidines; Structure-Activity Relationship | 1993 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Beta-L-1,3-dioxolane-cytidine: a novel nucleoside that inhibits proliferation and induces differentiation of keratinocytes in vitro.
Topics: Antimetabolites, Antineoplastic; Cell Differentiation; Cell Division; Cell Size; Cells, Cultured; Cytosine; Dioxolanes; Humans; Keratinocytes; Protein Precursors; Zidovudine | 1998 |