Page last updated: 2024-08-24

trovafloxacin and vancomycin

trovafloxacin has been researched along with vancomycin in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	16 (44.44)	18.2507
2000's	13 (36.11)	29.6817
2010's	7 (19.44)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chu, DT; Katz, L; Plattner, JJ	1
Inagaki, H; Kawakami, K; Kawato, HC; Matsuhashi, N; Miyauchi, RN; Miyauchi, S; Ohki, H; Takahashi, H; Takemura, M	1
Appelbaum, PC; Bhawsar, SB; Bozdogan, B; de Souza, NJ; Desai, VN; Deshpande, PK; Gupte, SV; Hooper, DC; Jacobs, MR; Jha, R; Khorakiwala, HF; Patel, MV; Shetty, N; Shukla, MC; Strahilevitz, J; Yeole, RD	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Inagaki, H; Ito, M; Kawakami, K; Matsuhashi, N; Miyauchi, R; Ohki, H; Takahashi, H; Takemura, M	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Hickey, SM; McCracken, GH; París, MM; Shelton, S; Trujillo, M	1
Cooper, B; Freeman, C; Mazens-Sullivan, M; Nightingale, C; Quintiliani, R; Robinson, A	1
Handwerger, S; Mildvan, D; Shonekan, D	1
Bradley, JS; Scheld, WM	1
Herrera-Insúa, I; Jacques-Palaz, K; Murray, BE; Rakita, RM	1
Andriole, VT; Dembry, LM; Farrel, PA; Gerrity, LA; Orcutt, DR	1
Maskell, JP; Rafay, AM; Sefton, AM; Whiley, A; Williams, JD	1
Canawati, HN; Montgomerie, JZ; Schick, DG	1
Nicolau, DP; Nightingale, CH; Quintiliani, R; Tessier, PR	1
Hoban, DJ; Karlowsky, JA; Zhanel, GG	1
Heisig, P; Jones, ME; Klootwijk, M; Schmitz, FJ; Verhoef, J; Visser, MR	1
Cohen, MA; Huband, MD	1
Aeschlimann, JR; Hershberger, E; Moldovan, T; Rybak, MJ	1
Cottagnoud, M; Cottagnoud, P; Gerber, CM; Hänni, F; Neftel, K; Rodoni, D; Täuber, MG	1
Bingen, E; Doit, C; Fitoussi, F; Geslin, P	1
Eckert, SJ; McNeeley, DF; Noel, GJ	1
Patel, R; Piper, KE; Ronningen, KL; Rouse, MS; Steckelberg, JM; Wilson, WR	1
McCracken, GH	1
Bakker-Woudenberg, IA; Goessens, WH; Gyssens, IC; Kooi, C; Stearne, LE	1
Siegel, M; Timpone, J	1
Cortés Sanchez, R; García Alberola, A; Gómez Gómez, J; López Fornas, F; Martínez García, F; Pérez Salmeron, J; Roldán Conesa, D; Ruíz Gómez, J; Valdés Chávarri, M	1
Bonner, D; Fung-Tomc, J; Gradelski, E; Kolek, B; Valera, L	1
Blanco, MT; Gómez-García, AC; Hurtado, C; Morán, FJ; Pérez-Giraldo, C; Sánchez-Silos, RM	1

Reviews

5 review(s) available for trovafloxacin and vancomycin

Article	Year
New directions in antibacterial research. Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Molecular Sequence Data; Molecular Structure	1996
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The challenge of penicillin-resistant Streptococcus pneumoniae meningitis: current antibiotic therapy in the 1990s. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24 Suppl 2 Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Child; Child, Preschool; Chloramphenicol; Clindamycin; Female; Fluoroquinolones; Humans; Infant; Infant, Newborn; Lactams; Male; Meningitis, Bacterial; Naphthyridines; Penicillin Resistance; Rifampin; Streptococcal Infections; Streptococcus pneumoniae; Vancomycin; Virginiamycin	1997
Pharmacodynamics of gatifloxacin in experimental models of pneumococcal meningitis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 31 Suppl 2 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Child; Disease Models, Animal; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combination; Fluoroquinolones; Gatifloxacin; Humans; Meningitis, Pneumococcal; Naphthyridines; Rabbits; Streptococcus pneumoniae; Vancomycin	2000
Penicillin-resistant Streptococcus pneumoniae endocarditis: a case report and review. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Mar-15, Volume: 32, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Endocarditis, Bacterial; Female; Fluoroquinolones; Humans; Middle Aged; Naphthyridines; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae; Vancomycin	2001

Other Studies

31 other study(ies) available for trovafloxacin and vancomycin

Article	Year
Synthesis and structure-activity relationships of 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methylquinolonecarboxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl] substituents. Journal of medicinal chemistry, 2003, Mar-13, Volume: 46, Issue:6 Topics: Anti-Bacterial Agents; Cyclopropanes; Drug Resistance, Bacterial; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Stereoisomerism; Structure-Activity Relationship	2003
A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus. Journal of medicinal chemistry, 2005, Aug-11, Volume: 48, Issue:16 Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Clinical Trials, Phase I as Topic; Dogs; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Half-Life; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Mutation; Prodrugs; Quinolizines; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vancomycin Resistance	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Design, synthesis and biological evaluations of novel 7-[3-(1-aminocycloalkyl)pyrrolidin-1-yl]-6-desfluoro-8-methoxyquinolones with potent antibacterial activity against multi-drug resistant Gram-positive bacteria. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Anti-Bacterial Agents; Drug Design; Drug Resistance, Multiple; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Structure-Activity Relationship	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Evaluation of CP-99,219, a new fluoroquinolone, for treatment of experimental penicillin- and cephalosporin-resistant pneumococcal meningitis. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:6 Topics: Animals; Anti-Infective Agents; Ceftriaxone; Cephalosporin Resistance; Colony Count, Microbial; Dexamethasone; Drug Evaluation; Drug Therapy, Combination; Fluoroquinolones; Humans; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Naphthyridines; Penicillin Resistance; Rabbits; Streptococcus pneumoniae; Vancomycin	1995
In vitro antimicrobial susceptibility of glycopeptide-resistant enterococci. Diagnostic microbiology and infectious disease, 1995, Volume: 21, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Depsipeptides; Drug Resistance, Microbial; Enterococcus; Fluoroquinolones; Fusidic Acid; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Novobiocin; Peptides, Cyclic; Quinolones; Teicoplanin; Vancomycin; Virginiamycin	1995
Comparative in-vitro activities of RP59500 (quinupristin/dalfopristin), CL 329,998, CL 331,002, trovafloxacin, clinafloxacin, teicoplanin and vancomycin against Gram-positive bacteria. The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Fluoroquinolones; Gram-Positive Bacteria; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Quinolones; Teicoplanin; Tetracyclines; Vancomycin; Virginiamycin	1997
Intracellular activity of trovafloxacin (CP-99,219) against Enterococcus faecium. The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:4 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Enterococcus faecium; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Neutrophils; Vancomycin	1997
In-vitro activity of trovafloxacin against sensitive and resistant aerobic bacteria using the standard microdilution broth method and Etest. The Journal of antimicrobial chemotherapy, 1997, Volume: 39 Suppl B Topics: Ampicillin; Anti-Infective Agents; Bacteria, Aerobic; Ciprofloxacin; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Fluoroquinolones; Gentamicins; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Sulbactam; Vancomycin	1997
The in-vitro activity of trovafloxacin, a new fluoroquinolone, against Gram-positive bacteria. The Journal of antimicrobial chemotherapy, 1997, Volume: 39 Suppl B Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Clindamycin; Erythromycin; Fluoroquinolones; Gram-Positive Bacteria; Lactams; Microbial Sensitivity Tests; Naphthyridines; Vancomycin	1997
In vitro activity of the combination of trovafloxacin and other antibiotics against enterococci. Diagnostic microbiology and infectious disease, 1997, Volume: 29, Issue:4 Topics: Ampicillin; Ampicillin Resistance; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Enterococcus; Enterococcus faecalis; Fluoroquinolones; Gentamicins; Humans; Microbial Sensitivity Tests; Naphthyridines; Novobiocin; Rifampin; Sulbactam; Teicoplanin; Vancomycin	1997
Synergistic activity of trovafloxacin and ceftriaxone or vancomycin against Streptococcus pneumoniae with various penicillin susceptibilities. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:4 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ceftriaxone; Cephalosporins; Drug Synergism; Fluoroquinolones; Humans; Naphthyridines; Penicillin Resistance; Streptococcal Infections; Streptococcus pneumoniae; Vancomycin	1998
In vitro activities of six fluoroquinolones against Canadian isolates of vancomycin-sensitive and vancomycin-resistant Enterococcus species. Diagnostic microbiology and infectious disease, 1998, Volume: 31, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Canada; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Quinolones; Vancomycin	1998
Comparative activities of clinafloxacin, grepafloxacin, levofloxacin, moxifloxacin, ofloxacin, sparfloxacin, and trovafloxacin and nonquinolones linozelid, quinupristin-dalfopristin, gentamicin, and vancomycin against clinical isolates of ciprofloxacin-re Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:2 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines; Quinolones; Staphylococcus aureus; Vancomycin; Virginiamycin	1999
Activity of clinafloxacin, trovafloxacin, quinupristin/dalfopristin, and other antimicrobial agents versus Staphylococcus aureus isolates with reduced susceptibility to vancomycin. Diagnostic microbiology and infectious disease, 1999, Volume: 33, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Staphylococcus aureus; Vancomycin; Virginiamycin	1999
Evaluation of bactericidal activities of LY333328, vancomycin, teicoplanin, ampicillin-sulbactam, trovafloxacin, and RP59500 alone or in combination with rifampin or gentamicin against different strains of vancomycin-intermediate Staphylococcus aureus by Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:3 Topics: Ampicillin; Anti-Bacterial Agents; Antibiotics, Antitubercular; Drug Therapy, Combination; Fluoroquinolones; Gentamicins; Glycopeptides; Lipoglycopeptides; Microbial Sensitivity Tests; Naphthyridines; Rifampin; Staphylococcus aureus; Sulbactam; Teicoplanin; Time Factors; Vancomycin; Virginiamycin	1999
Trovafloxacin in combination with vancomycin against penicillin-resistant pneumococci in the rabbit meningitis model. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:4 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Disease Models, Animal; Drug Therapy, Combination; Fluoroquinolones; Meningitis, Pneumococcal; Naphthyridines; Penicillin Resistance; Rabbits; Streptococcus pneumoniae; Time Factors; Vancomycin	1999
Killing activities of trovafloxacin alone and in combination with beta-lactam agents, rifampin, or vancomycin against Streptococcus pneumoniae isolates with various susceptibilities to extended-spectrum cephalosporins at concentrations clinically achievab Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:10 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Cephalosporin Resistance; Cephalosporins; Drug Interactions; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Rifampin; Streptococcus pneumoniae; Vancomycin	1999
Antimicrobial-resistant enterococcal isolates from fluoroquinolone-naive children. The Pediatric infectious disease journal, 2000, Volume: 19, Issue:7 Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Child, Preschool; Ciprofloxacin; Drug Resistance, Microbial; Enterococcus faecalis; Enterococcus faecium; Fluoroquinolones; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Naphthyridines; Penicillins; Vancomycin	2000
Trovafloxacin treatment of viridans group Streptococcus experimental endocarditis. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:9 Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Disease Models, Animal; Endocarditis, Bacterial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Penicillins; Rabbits; Streptococcal Infections; Streptococcus; Treatment Outcome; Vancomycin	2000
In vitro activity of trovafloxacin against Bacteroides fragilis in mixed culture with either Escherichia coli or a vancomycin- resistant strain of Enterococcus faecium determined by an anaerobic time-kill technique. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:1 Topics: Anaerobiosis; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteroides fragilis; Cecum; Colony Count, Microbial; Enterococcus faecium; Escherichia coli; Fluoroquinolones; Mice; Microbial Sensitivity Tests; Naphthyridines; Time Factors; Vancomycin; Vancomycin Resistance	2001
Comparative study of treatment with penicillin, ceftriaxone, trovafloxacin, quinupristin-dalfopristin and vancomycin in experimental endocarditis due to penicillin- and ceftriaxone-resistant Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:5 Topics: Animals; Anti-Infective Agents; Ceftriaxone; Disease Models, Animal; Drug Resistance, Multiple; Endocarditis, Bacterial; Fluoroquinolones; Humans; Male; Naphthyridines; Penicillin Resistance; Penicillins; Pneumococcal Infections; Rabbits; Streptococcus pneumoniae; Vancomycin; Virginiamycin	2001
Comparative killing kinetics of the novel des-fluoro(6) quinolone BMS-284756, fluoroquinolones, vancomycin and beta-lactams. International journal of antimicrobial agents, 2001, Volume: 18, Issue:1 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; beta-Lactams; Enterobacteriaceae; Enterococcus faecalis; Fluoroquinolones; Indoles; Kinetics; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Quinolones; Staphylococcus aureus; Streptococcus; Vancomycin	2001
Resistance to vancomycin, LY333328, ciprofloxacin and trovafloxacin of community-acquired and nosocomial strains of Enterococcus faecalis isolated in Badajoz (Spain) with and without high-level resistance to streptomycin and gentamicin. Chemotherapy, 2001, Volume: 47, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Enterococcus faecalis; Fluoroquinolones; Gentamicins; Glycopeptides; Gram-Positive Bacterial Infections; Humans; Incidence; Lipoglycopeptides; Microbial Sensitivity Tests; Naphthyridines; Spain; Streptomycin; Vancomycin	2001