Page last updated: 2024-08-24

trovafloxacin and gemifloxacin

trovafloxacin has been researched along with gemifloxacin in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	26 (89.66)	29.6817
2010's	2 (6.90)	24.3611
2020's	1 (3.45)	2.80

Authors

Authors	Studies
Inagaki, H; Kawakami, K; Kawato, HC; Matsuhashi, N; Miyauchi, RN; Miyauchi, S; Ohki, H; Takahashi, H; Takemura, M	1
Choi, DR; Jung, YH; Shin, JH; Yang, J; Yoon, SH	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Blaskovich, MAT; Pham, TDM; Ziora, ZM	1
Brady, SF; Koirala, B; Peek, J	1
Amsterdam, D; Hardy, D; Mandell, LA; Rotstein, C	1
Aguilar, L; Alou, L; Fuentes, F; Giménez, MJ; Marco, F; Prieto, J	1
Edmond, M; Heinemann, B; Seifert, H; Wisplinghoff, H	1
Clark, S; Mathias, I; Morrissey, I	1
Kanayama, A; Kobayashi, I; Mochida, O; Naito, S; Saika, T; Tanaka, M; Tunoe, H	1
Ferraro, MJ; Jorgensen, JH; Swenson, JM; Tenover, FC; Weigel, LM; Whitney, CG	1
Hollauer, K; Kirchbauer, D; Naber, KG; Witte, W	1
Aguilar, L; Garcia-Calvo, G; Giménez, MJ; Molleja, A; Nieto, E; Parra, A; Ponte, C; Soriano, F	1
Aguilar, L; Carcas, A; García-Calvo, G; Giménez, MJ; Kinzig-Schippers, M; Parra, A; Ponte, C; Soriano, F	1
Ball, P; Brown, J; Henkel, T; Mandell, L; Wilson, R	1
Cupo, M; File, TM; Garau, J; Schlemmer, B; Young, C	1
Appelbaum, PC; Davies, TA; Dewasse, BE; Jacobs, MR; Nagai, K	1
Cornaglia, G; Firsov, AA; Lubenko, IY; Portnoy, YA; Vostrov, SN; Zinner, SH	1
Aguilar, L; Alou, L; Dal-Ré, R; Frías, J; Fuentes, F; Giménez, MJ; Prieto, J; Sörgel, F	1
Hammerschlag, MR	1
Aguilar, L; García, I; Giménez, MJ; Joyanes, P; Pascual, A; Perea, E	1
Evans, ME	1
Goldstein, EJ	1
Aguilar, L; Alou, L; Calvo, A; Giménez, MJ; Gómez-Lus, ML; Prieto, J	1
Aguilar, L; García-Calvo, G; Giménez, MJ; Parra, A; Ponte, C; Soriano, F	1
Aguilar, L; Garcia-Mendez, E; Jiménez De Anta, MT; Marco, F; Mensa, J; Ruiz, J; Sierra, JM; Vila, J	1
Aguilar, L; Blanquer, R; Caminero, J; Custardoy, J; Dal-Ré, R; Durán, J; García-Méndez, E; García-Rey, C; Gil-Aguado, A; Grau, I; Ibáñez, D; Llorca, E; Martínez, J; Mensa, J; Molinos, L; Moreno, S; Palacios, R; Pallarés, R; Santos, J; Siquier, B; Vidal, J	1
Cabeza, JG; Hernandez, J; Llagostera, M; Mensa, J; Montero, T; Ruiz Chaler, M; Sierra, JM; Vila, J	1
Boada, C; Boada, JN; Fernández, E; García, M; García-Sáiz, M; Gómez, E	1

Reviews

2 review(s) available for trovafloxacin and gemifloxacin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Quinolone antibiotics. MedChemComm, 2019, Oct-01, Volume: 10, Issue:10 Topics:	2019

Trials

8 trial(s) available for trovafloxacin and gemifloxacin

Article	Year
Effects of single oral doses of gemifloxacin (320 milligrams) versus trovafloxacin (200 milligrams) on fecal flora in healthy volunteers. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:2 Topics: Anti-Infective Agents; Bacteroides fragilis; Colony Count, Microbial; Cross-Over Studies; Escherichia coli; Feces; Fluoroquinolones; Gemifloxacin; Humans; Naphthyridines	2001
Antibacterial properties of gemifloxacin and trovafloxacin in urine ex vivo: phase I study. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:6 Topics: Administration, Oral; Adult; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid; Escherichia coli; Fluoroquinolones; Gemifloxacin; Humans; Male; Microbial Sensitivity Tests; Naphthyridines; Staphylococcus	2001
Efficacy of gemifloxacin in acute exacerbations of chronic bronchitis: a randomised, double-blind comparison with trovafloxacin. Journal of chemotherapy (Florence, Italy), 2001, Volume: 13, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bronchitis, Chronic; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Female; Fluoroquinolones; Follow-Up Studies; Gemifloxacin; Humans; Lung; Male; Middle Aged; Naphthyridines; Time Factors; Treatment Outcome	2001
Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: a randomized, double-blind comparison with trovafloxacin. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Community-Acquired Infections; Double-Blind Method; Drug Resistance, Microbial; Female; Fluoroquinolones; Gemifloxacin; Humans; Male; Middle Aged; Naphthyridines; Pneumonia, Bacterial	2001
Influence of diminished susceptibility of Streptococcus pneumoniae to ciprofloxacin on the serum bactericidal activity of gemifloxacin and trovafloxacin after a single dose in healthy volunteers. International journal of antimicrobial agents, 2001, Volume: 18, Issue:3 Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Humans; Male; Microbial Sensitivity Tests; Naphthyridines; Serum Bactericidal Test; Streptococcus pneumoniae	2001
Ex vivo serum activity (killing rates) after gemifloxacin 320 mg versus trovafloxacin 200 mg single doses against ciprofloxacin-susceptible and -resistant Streptococcus pneumoniae. International journal of antimicrobial agents, 2002, Volume: 20, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Cross-Over Studies; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Humans; Male; Microbial Sensitivity Tests; Naphthyridines; Serum Bactericidal Test; Streptococcus pneumoniae	2002
Urine bactericidal activity after administration of gemifloxacin and trovafloxacin single doses in a phase I study. International journal of antimicrobial agents, 2002, Volume: 20, Issue:6 Topics: Adult; Anti-Infective Agents; Cross-Over Studies; Escherichia coli; Fluoroquinolones; Gemifloxacin; Humans; Male; Microbial Sensitivity Tests; Naphthyridines; Staphylococcus; Time Factors	2002
Clinical characteristics and response to newer quinolones in Legionella pneumonia: a report of 28 cases. Journal of chemotherapy (Florence, Italy), 2003, Volume: 15, Issue:5 Topics: Community-Acquired Infections; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Humans; Immunoglobulin G; Legionella; Legionellosis; Naphthyridines; Pneumonia; Treatment Outcome	2003

Other Studies

19 other study(ies) available for trovafloxacin and gemifloxacin

Article	Year
Synthesis and structure-activity relationships of 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methylquinolonecarboxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl] substituents. Journal of medicinal chemistry, 2003, Mar-13, Volume: 46, Issue:6 Topics: Anti-Bacterial Agents; Cyclopropanes; Drug Resistance, Bacterial; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Stereoisomerism; Structure-Activity Relationship	2003
Syntheses and biological evaluation of new fluoroquinolone antibacterials containing chiral oxiimino pyrrolidine. Bioorganic & medicinal chemistry letters, 2004, Mar-08, Volume: 14, Issue:5 Topics: Animals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Fluoroquinolones; Microbial Sensitivity Tests; Pyrrolidines; Rats; Stereoisomerism	2004
Synthesis and evaluation of dual-action kanglemycin-fluoroquinolone hybrid antibiotics. Bioorganic & medicinal chemistry letters, 2022, 02-01, Volume: 57 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Escherichia coli; Fluoroquinolones; HEK293 Cells; Humans; Microbial Sensitivity Tests; Rifamycins; Staphylococcus aureus	2022
Comparative in vitro activities of ciprofloxacin, gemifloxacin, grepafloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxacin, and other antimicrobial agents against bloodstream isolates of gram-positive cocci. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Bacteremia; Ciprofloxacin; Fluoroquinolones; Gemifloxacin; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Piperazines; Quinolines	2000
In vitro susceptibility to gemifloxacin and trovafloxacin of Streptococcus pneumoniae strains exhibiting decreased susceptibility to ciprofloxacin. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2000, Volume: 19, Issue:2 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Humans; Microbial Sensitivity Tests; Naphthyridines; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae	2000
Comparative activities of ciprofloxacin, clinafloxacin, gatifloxacin, gemifloxacin, levofloxacin, moxifloxacin, and trovafloxacin against epidemiologically defined Acinetobacter baumannii strains. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:8 Topics: Acinetobacter; Acinetobacter Infections; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Disease Outbreaks; Drug Resistance, Microbial; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Germany; Humans; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines	2000
The bactericidal activity of gemifloxacin (SB-265805). Journal of medical microbiology, 2000, Volume: 49, Issue:9 Topics: Anti-Infective Agents; Escherichia coli; Fluoroquinolones; Gemifloxacin; Naphthyridines; Staphylococcus aureus; Streptococcus pneumoniae	2000
Antimicrobial activity of gemifloxacin (SB-265805), a newer fluoroquinolone, against clinical isolates of Neisseria gonorrhoeae, including fluoroquinolone-resistant isolates. Diagnostic microbiology and infectious disease, 2000, Volume: 38, Issue:2 Topics: Amoxicillin; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Gonorrhea; Humans; Levofloxacin; Naphthyridines; Neisseria gonorrhoeae; Norfloxacin; Ofloxacin	2000
Activities of clinafloxacin, gatifloxacin, gemifloxacin, and trovafloxacin against recent clinical isolates of levofloxacin-resistant Streptococcus pneumoniae. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11 Topics: Anti-Bacterial Agents; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Streptococcus pneumoniae	2000
In vitro activity of gatifloxacin compared with gemifloxacin, moxifloxacin, trovafloxacin, ciprofloxacin and ofloxacin against uropathogens cultured from patients with complicated urinary tract infections. International journal of antimicrobial agents, 2000, Volume: 16, Issue:3 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Escherichia coli; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Klebsiella; Microbial Sensitivity Tests; Moxifloxacin; Naphthyridines; Ofloxacin; Quinolines; Urinary Tract Infections	2000
Single- and multi-step resistance selection study of gemifloxacin compared with trovafloxacin, ciprofloxacin, gatifloxacin and moxifloxacin in Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:3 Topics: Anti-Infective Agents; Aza Compounds; Biological Transport; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluoroquinolones; Gatifloxacin; Gemifloxacin; Humans; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Naphthyridines; Quinolines; Selection, Genetic; Serotyping; Streptococcus pneumoniae	2001
Comparative anti-staphylococcal effects of gemifloxacin and trovafloxacin in an in vitro dynamic model in terms of AUC/MIC and dose relationships. Diagnostic microbiology and infectious disease, 2001, Volume: 40, Issue:4 Topics: Anti-Infective Agents; Area Under Curve; Dose-Response Relationship, Drug; Escherichia coli; Fluoroquinolones; Gemifloxacin; Microbial Sensitivity Tests; Models, Biological; Naphthyridines; Predictive Value of Tests; Staphylococcus aureus	2001
Efficacy and safety of gemifloxacin in the treatment of community-acquired pneumonia: a randomized, double-blind comparison with trovafloxacin. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:5 Topics: Anti-Infective Agents; Community-Acquired Infections; Double-Blind Method; Fluoroquinolones; Gemifloxacin; Humans; Naphthyridines; Pneumonia; Randomized Controlled Trials as Topic	2001
Differences between two new quinolones (gemifloxacin and trovafloxacin) and ciprofloxacin in their concentration-dependent killing of Streptococcus pneumoniae. Chemotherapy, 2001, Volume: 47, Issue:6 Topics: Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Microbial Sensitivity Tests; Naphthyridines; Streptococcus pneumoniae	2001
Determining the frequency of resistance of Streptococcus pneumoniae to ciprofloxacin, levofloxacin, trovafloxacin, grepafloxacin, and gemifloxacin. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:12 Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Gemifloxacin; Humans; Levofloxacin; Microbial Sensitivity Tests; Naphthyridines; Ofloxacin; Piperazines; Streptococcus pneumoniae	2001
Intra-abdominal anaerobic infections: bacteriology and therapeutic potential of newer antimicrobial carbapenem, fluoroquinolone, and desfluoroquinolone therapeutic agents. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Sep-01, Volume: 35, Issue:Suppl 1 Topics: Abdominal Abscess; Anti-Bacterial Agents; Aza Compounds; Bacteremia; Bacteria, Anaerobic; Bacteroides fragilis; Bacteroides Infections; beta-Lactams; Carbapenems; Clinical Trials as Topic; Ertapenem; Fluoroquinolones; Gemifloxacin; Humans; Indoles; Lactams; Moxifloxacin; Naphthyridines; Quinolines; Quinolones	2002
In vitro activity of gemifloxacin against clinical isolates of Neisseria gonorrhoeae with and without mutations in the gyrA gene. International journal of antimicrobial agents, 2003, Volume: 22, Issue:1 Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Genes, Bacterial; Gonorrhea; Humans; In Vitro Techniques; Levofloxacin; Microbial Sensitivity Tests; Moxifloxacin; Mutation; Nalidixic Acid; Naphthyridines; Neisseria gonorrhoeae; Ofloxacin; Quinolines	2003
The selection of resistance to and the mutagenicity of different fluoroquinolones in Staphylococcus aureus and Streptococcus pneumoniae. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:9 Topics: Aza Compounds; Ciprofloxacin; DNA Gyrase; DNA Topoisomerase IV; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Fluoroquinolones; Gemifloxacin; Levofloxacin; Moxifloxacin; Mutagenicity Tests; Naphthyridines; Ofloxacin; Quinolines; Selection, Genetic; Staphylococcus aureus; Streptococcus pneumoniae	2005
Net efficacy adjusted for risk (NEAR): a simple procedure for measuring risk:benefit balance. PloS one, 2008, Volume: 3, Issue:10 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Cardiovascular Diseases; Drug-Related Side Effects and Adverse Reactions; Fluoroquinolones; Gemifloxacin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Models, Theoretical; Naphthyridines; Pneumonia; Preventive Medicine; Randomized Controlled Trials as Topic; Risk Assessment; Treatment Outcome	2008