tropolone has been researched along with colchicine in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (51.35) | 18.7374 |
| 1990's | 13 (35.14) | 18.2507 |
| 2000's | 3 (8.11) | 29.6817 |
| 2010's | 1 (2.70) | 24.3611 |
| 2020's | 1 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Bhattacharyya, B; Cortese, F; Wolff, J | 1 |
| Prakash, V; Timasheff, SN | 1 |
| Casal Jimenez, J; Gonzalez, C; Ripoll, P; Sunkel, CE | 1 |
| Hamel, E; Hesson, DP; Jiang, JB; Kang, GJ; Lin, CM; Luduena, RF; Roach, MC | 1 |
| Andreu, JM; Gorbunoff, MJ; Medrano, FJ; Timasheff, SN | 1 |
| Andreu, JM; Gorbunoff, MJ; Medrano, FJ; Rossi, M; Timasheff, SN | 1 |
| Busson, S; Gorbunoff, MJ; Herman, G; Mauduit, P; Rossignol, B; Timasheff, SN | 1 |
| Andreu, JM; Mollinedo, F; Nieto, JM | 1 |
| Andreu, JM; Laynez, J; Medrano, FJ; Menéndez, M | 1 |
| Hamel, E; Ho, HH; Lin, CM; Pettit, GR | 1 |
| Bhattacharyya, B; Biswas, BB; Ghosh Choudhury, G; Maity, S | 1 |
| Banerjee, A; Hashigaki, K; Luduena, RF; Sakai, J; Tashiro, T; Tsukagoshi, S; Tsuruo, T; Yamato, M; Yasumoto, Y | 1 |
| Engelborghs, Y; Fitzgerald, TJ | 1 |
| Andreu, JM; Avila, J; Díez, JC; Nieto, JM | 1 |
| Bane, S; Ludueña, RF; Roach, MC | 1 |
| Lee, JC; Link, J; Rossi, M | 1 |
| Andreu, JM; Timasheff, SN | 1 |
| Schrek, R; Stefani, SS | 1 |
| Bhattacharyya, B; Biswas, BB; Ray, K | 1 |
| Rosenthal, JW | 1 |
| Gershbein, LL | 1 |
| Andreu, JM; Billger, M; de Pereda, JM; Wallin, M | 1 |
| Bhattacharyya, B; Sackett, DL; Wolff, J | 1 |
| D'Hoore, A; Dumortier, C; Engelborghs, Y; Fitzgerald, TJ; Vandecandelaere, A | 1 |
| Andreu, JM; Dumortier, C; Engelborghs, Y; Gorbunoff, MJ | 1 |
| Banerjee, A | 1 |
| Banerjee, A; D'Hoore, A; Engelborghs, Y; Fitzgerald, TJ | 1 |
| Bane, S; Dumortier, C; Engelborghs, Y; Potenziano, JL | 1 |
| Chaudhuri, AR; Ludueña, RF; Mizuhashi, F; Murata, K; Potenziano, JL; Tomita, I | 1 |
| Basusarkar, P; Bhattacharyya, B; Bhattacharyya, S; Manna, T; Roy, S; Roychowdhury, M; Sarkar, N; Sarkar, T | 1 |
| Chaudhuri, AR; Hausheer, FH; Ludueña, RF; Schwarz, PM; Seetharamalu, P | 1 |
| BENITEZ, HH; CHARGAFF, E; MURRAY, MR | 1 |
| GOLDSTEIN, M; LAUBER, E; MCKEREGHAN, MR | 1 |
| AKAISHI, K; SATO, K | 1 |
| DeShong, P; Handy, CJ; Seganish, WM | 1 |
| Al-Fahad, A; Cox, RJ | 1 |
| Bartl, F; Przybylski, P; Pyta, K; Ruszkowski, P; Skrzypczak, N | 1 |
1 review(s) available for tropolone and colchicine
| Article | Year |
|---|---|
Chemical mechanisms involved during the biosynthesis of tropolones.
Topics: Biological Products; Biosynthetic Pathways; Colchicine; Tropolone | 2013 |
36 other study(ies) available for tropolone and colchicine
| Article | Year |
|---|---|
Podophyllotoxin as a probe for the colchicine binding site of tubulin.
Topics: Animals; Binding Sites; Brain; Colchicine; Demecolcine; Glycoproteins; Hydrogen-Ion Concentration; Kinetics; Podophyllotoxin; Protein Binding; Rats; Spectrometry, Fluorescence; Tropolone; Tubulin | 1977 |
Aging of tubulin at neutral pH: stabilization by colchicine and its analogues.
Topics: Animals; Brain Chemistry; Cattle; Circular Dichroism; Colchicine; Hydrogen-Ion Concentration; Protein Conformation; Spectrophotometry, Ultraviolet; Tropolone; Tubulin; Ultracentrifugation; Vincristine | 1992 |
The spindle is required for the process of sister chromatid separation in Drosophila neuroblasts.
Topics: Animals; Chromatids; Colchicine; Drosophila melanogaster; Ganglia; Heterochromatin; Metaphase; Microtubules; Mitosis; Spindle Apparatus; Tropolone | 1991 |
Investigation of the mechanism of the interaction of tubulin with derivatives of 2-styrylquinazolin-4(3H)-one.
Topics: Antineoplastic Agents; Binding Sites; Colchicine; Guanosine Triphosphate; Quinazolines; Styrenes; Tropolone; Tubulin | 1991 |
Roles of ring C oxygens in the binding of colchicine to tubulin.
Topics: Binding, Competitive; Biphenyl Compounds; Circular Dichroism; Colchicine; Kinetics; Ligands; Oxygen; Protein Conformation; Spectrometry, Fluorescence; Thermodynamics; Tropolone; Tubulin | 1991 |
Mechanism of colchicine binding to tubulin. Tolerance of substituents in ring C' of biphenyl analogues.
Topics: Animals; Binding Sites; Biphenyl Compounds; Colchicine; GTP Phosphohydrolases; Hydrolysis; In Vitro Techniques; Kinetics; Ligands; Microtubules; Models, Molecular; Protein Conformation; Thermodynamics; Tropolone; Tubulin | 1991 |
Colchicine analogues that bind reversibly to tubulin define microtubular requirements for newly synthesized protein secretion in rat lacrimal gland.
Topics: Animals; Biphenyl Compounds; Colchicine; Cycloheptanes; Fluorescent Antibody Technique; Kinetics; Lacrimal Apparatus; Male; Microtubules; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Tropolone; Tubulin | 1989 |
Cytoplasmic microtubules in human neutrophil degranulation: reversible inhibition by the colchicine analogue 2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1- one.
Topics: Cell Degranulation; Colchicine; Cycloheptanes; Cytochalasin B; Cytoplasmic Granules; Exocytosis; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Microtubules; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Time Factors; Tropolone | 1989 |
A thermodynamic study of the interaction of tubulin with colchicine site ligands.
Topics: Animals; Binding Sites; Brain; Calorimetry; Cattle; Colchicine; Kinetics; Ligands; Protein Binding; Thermodynamics; Tropolone; Tubulin | 1989 |
Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin.
Topics: Animals; Bibenzyls; Binding Sites; Brain; Cattle; Colchicine; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Mitosis; Models, Structural; Plant Extracts; Podophyllotoxin; Protein Binding; Stilbenes; Tropolone; Tubulin | 1989 |
B-ring of colchicine and its role in taxol-induced tubulin polymerization.
Topics: Alkaloids; Animals; Brain Chemistry; Chemical Phenomena; Chemistry; Colchicine; Goats; Macromolecular Substances; Paclitaxel; Spectrometry, Fluorescence; Structure-Activity Relationship; Tropolone; Tubulin | 1986 |
Synthesis and antitumor activity of tropolone derivatives. 6. Structure-activity relationships of antitumor-active tropolone and 8-hydroxyquinoline derivatives.
Topics: Animals; Antineoplastic Agents; Colchicine; Cycloheptanes; Hydroxyquinolines; Leukemia P388; Mice; Oxyquinoline; Structure-Activity Relationship; Tropolone | 1987 |
Kinetic and thermodynamic aspects of tubulin-ligand interactions: binding of the colchicine analog 2-methoxy-5-(2',3',4'-trimethoxyphenyl) tropone.
Topics: Animals; Brain; Colchicine; Cycloheptanes; Kinetics; Ligands; Microtubules; Protein Binding; Swine; Thermodynamics; Tropolone; Tubulin | 1986 |
Reversible inhibition of microtubules and cell growth by the bicyclic colchicine analogue MTC.
Topics: Animals; Cell Division; Cell Line; Cells, Cultured; Colchicine; Cycloheptanes; Microtubules; Mitotic Index; Tropolone | 1987 |
The effects of colchicine analogues on the reaction of tubulin with iodo[14C]acetamide and N,N'-ethylenebis(iodoacetamide).
Topics: Alkylation; Animals; Benzaldehydes; Benzimidazoles; Colchicine; Ethylenediamines; Iodoacetamide; Iodoacetates; Mathematics; Nocodazole; Podophyllotoxin; Rabbits; Tropolone; Tubulin | 1985 |
The structure of 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone, an effective analog of colchicine.
Topics: Chemical Phenomena; Chemistry; Colchicine; Computers; Cycloheptanes; Models, Molecular; Structure-Activity Relationship; Tropolone; X-Ray Diffraction | 1984 |
Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxin.
Topics: Animals; Brain Chemistry; Cattle; Circular Dichroism; Colchicine; Cycloheptanes; Mathematics; Podophyllotoxin; Protein Conformation; Tropolone; Tubulin | 1982 |
Toxicity of microtubular drugs to leukemic lymphocytes.
Topics: Benzimidazoles; Carbamates; Colchicine; Humans; Leukemia, Lymphoid; Lymphocytes; Maytansine; Microtubules; Nocodazole; Podophyllotoxin; Tropolone; Vinblastine; Vincristine | 1981 |
Role of B-ring of colchicine in its binding to tubulin.
Topics: Animals; Chemical Phenomena; Chemistry; Colchicine; Demecolcine; Goats; Kinetics; Protein Binding; Structure-Activity Relationship; Tropolone; Tubulin | 1981 |
Decrease in glucose oxidation in isolated brown fat cells from rats due to tropolone and dimethoxybenzene.
Topics: Adipose Tissue, Brown; Animals; Anisoles; Colchicine; Cycloheptanes; Glucose; In Vitro Techniques; Oxidation-Reduction; Rats; Structure-Activity Relationship; Tropolone | 1981 |
Rat liver regeneration in the presence of nonbenzenoid aromatic agents: ferrocenes and cycloheptatrienes.
Topics: Animals; Body Weight; Colchicine; Cycloheptanes; Female; Ferrous Compounds; Iron; Liver Regeneration; Male; Metallocenes; Organ Size; Organometallic Compounds; Rats; Tropolone | 1980 |
Comparative study of the colchicine binding site and the assembly of fish and mammalian microtubule proteins.
Topics: Animals; Binding Sites; Cattle; Colchicine; Fishes; Microtubule Proteins; Species Specificity; Tropolone | 1995 |
Local unfolding and the stepwise loss of the functional properties of tubulin.
Topics: Anilino Naphthalenesulfonates; Animals; Brain Chemistry; Chymotrypsin; Colchicine; Fluorescent Dyes; GTP Phosphohydrolases; Kinetics; Microtubules; Polymers; Protein Folding; Rats; Spectrometry, Fluorescence; Tropolone; Trypsin; Tryptophan; Tubulin; Urea | 1994 |
Evidence for an alternative pathway for colchicine binding to tubulin, based on the binding kinetics of the constituent rings.
Topics: Acetophenones; Animals; Brain; Colchicine; Kinetics; Mathematics; Microtubules; Models, Theoretical; Protein Binding; Swine; Thermodynamics; Tropolone; Tubulin | 1993 |
Alterations of rings B and C of colchicine are cumulative in overall binding to tubulin but modify each kinetic step.
Topics: Biphenyl Compounds; Colchicine; Dimerization; Fluorescence; Kinetics; Models, Chemical; Molecular Structure; Podophyllotoxin; Protein Binding; Thermodynamics; Tropolone; Tubulin | 1996 |
Differential effects of colchicine and its B-ring modified analog MTPT on the assembly-independent GTPase activity of purified beta-tubulin isoforms from bovine brain.
Topics: Animals; Brain Chemistry; Cattle; Colchicine; GTP Phosphohydrolases; Tropolone; Tubulin; Tubulin Modulators | 1997 |
Interactions of a bicyclic analog of colchicine with beta-tubulin isoforms alphabeta(II), alphabeta(III) and alphabeta(IV).
Topics: Colchicine; Dimerization; Isomerism; Kinetics; Tropolone; Tubulin | 1997 |
The mechanism of tubulin-colchicine recognition--a kinetic study of the binding of a bicyclic colchicine analogue with a minor modification of the A ring.
Topics: Animals; Anisoles; Binding Sites; Binding, Competitive; Colchicine; Cycloheptanes; In Vitro Techniques; Kinetics; Ligands; Molecular Structure; Protein Binding; Swine; Thermodynamics; Tropolone; Tubulin | 1997 |
IKP104-induced decay of tubulin: role of the A-ring binding site of colchicine.
Topics: Alkylation; Animals; Benzaldehydes; Binding Sites; Cattle; Colchicine; Protein Conformation; Pyridones; Spectrometry, Fluorescence; Tropolone; Tubulin; Tubulin Modulators | 1998 |
Sulfhydryls of tubulin. A probe to detect conformational changes of tubulin.
Topics: Anilino Naphthalenesulfonates; Animals; Colchicine; Cysteine; Dithionitrobenzoic Acid; Protein Conformation; Rabbits; Sulfhydryl Compounds; Sulfhydryl Reagents; Time Factors; Tropolone; Tubulin | 2000 |
The interaction of the B-ring of colchicine with alpha-tubulin: a novel footprinting approach.
Topics: Amino Acid Sequence; Animals; Bibenzyls; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Colchicine; Fluorescence; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Podophyllotoxin; Protein Conformation; Protein Footprinting; Stilbenes; Tropolone; Tryptophan; Tubulin; Urea | 2000 |
Antagonism between tropolone and colchicine in rat fibroblast cultures.
Topics: Animals; Colchicine; Fibroblasts; Rats; Research Design; Tissue Culture Techniques; Tropolone | 1953 |
THE INHIBITION OF DOPAMINE-BETA-HYDROXYLASE BY TROPOLONE AND OTHER CHELATING AGENTS.
Topics: Carbon Isotopes; Chelating Agents; Cobalt; Colchicine; Dopamine; Dopamine beta-Hydroxylase; Edetic Acid; Enzyme Inhibitors; Iron; Mixed Function Oxygenases; Myocardium; Octopamine; Phenanthrolines; Research; Spleen; Tropolone; Tyramine | 1964 |
Effect of tropolone and related compounds (compounds having unsaturated seven membres ring structure) on Yoshida sarcoma. I.
Topics: Animals; Colchicine; Prostheses and Implants; Sarcoma, Experimental; Sarcoma, Yoshida; Tropolone | 1951 |
Efforts directed toward the synthesis of colchicine: application of palladium-catalyzed siloxane cross-coupling methodology.
Topics: Bromus; Catalysis; Colchicine; Cross-Linking Reagents; Molecular Structure; Palladium; Silanes; Siloxanes; Stereoisomerism; Tropolone | 2005 |
Regioselective approach to colchiceine tropolone ring functionalization at C(9) and C(10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colchicine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Molecular Docking Simulation; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Tropolone; Tubulin; Tubulin Modulators | 2022 |