tropolone has been researched along with beta-thujaplicinol in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| D'Erasmo, MP; Hirsch, DR; Meck, C; Murelli, RP | 1 |
| Beutler, JA; Bona, MK; Budihas, SR; Crouch, RJ; Gaidamakov, S; Gorshkova, I; Le Grice, SF; McMahon, JB; Parniak, MA; Wamiru, A | 1 |
| Arnold, E; Bauman, JD; Bergqvist, S; Clark, AD; Das, K; Dharia, C; Hickey, MJ; Himmel, DM; Hughes, SH; Love, RA; Maegley, KA; Pauly, TA; Ryan, K | 1 |
| Cao, F; Cheng, X; Hu, Y; Huang, A; Tavis, JE | 1 |
| Herman, BD; Sluis-Cremer, N | 1 |
| Beutler, JA; Le Grice, SF; Lin, Z; Lynn, AY; Murelli, RP; Tang, L; Varnado, B; Zhao, H | 1 |
| Lomonosova, E; Tavis, JE; Zlotnick, A | 1 |
| Álvarez, M; Chen, CH; Cheng, X; De Clercq, E; Gao, P; Kongsted, J; Lee, KH; Liu, H; Liu, X; Luczkowiak, J; Menéndez-Arias, L; Pannecouque, C; Poongavanam, V; Sun, L; Wang, X; Zhan, P | 1 |
| Cheng, X; Frutos-Beltrán, E; Kang, D; Liu, X; Luczkowiak, J; Martín-Alonso, S; Martínez Del Río, J; Menéndez-Arias, L; Zhan, P; Zhang, L | 1 |
9 other study(ies) available for tropolone and beta-thujaplicinol
| Article | Year |
|---|---|
The biology and synthesis of α-hydroxytropolones.
Topics: | 2014 |
Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones.
Topics: Anti-HIV Agents; Benzocycloheptenes; Binding Sites; Coumarins; HIV-1; Pyranocoumarins; Reverse Transcriptase Inhibitors; Ribonuclease H; Tropolone | 2005 |
Structure of HIV-1 reverse transcriptase with the inhibitor beta-Thujaplicinol bound at the RNase H active site.
Topics: Catalytic Domain; Crystallography, X-Ray; HIV Reverse Transcriptase; Models, Molecular; Protein Binding; Protein Conformation; Reverse Transcriptase Inhibitors; Ribonucleases; Tropolone | 2009 |
β-Thujaplicinol inhibits hepatitis B virus replication by blocking the viral ribonuclease H activity.
Topics: Antiviral Agents; Cell Line, Tumor; Hepatitis B; Hepatitis B virus; Humans; Ribonuclease H; Tropolone; Viral Proteins; Virus Replication | 2013 |
Transient kinetic analyses of the ribonuclease H cleavage activity of HIV-1 reverse transcriptase in complex with efavirenz and/or a β-thujaplicinol analogue.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Binding Sites; Cyclopropanes; HIV Reverse Transcriptase; Kinetics; Reverse Transcriptase Inhibitors; Ribonuclease H; Tropolone | 2013 |
Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism.
Topics: Biocatalysis; Catalytic Domain; DNA Packaging; Endodeoxyribonucleases; Lysine; Magnesium; Manganese; Metals; Models, Molecular; Mutation; Podoviridae; Protein Binding; Tropolone; Viral Proteins | 2015 |
Synergistic Interactions between Hepatitis B Virus RNase H Antagonists and Other Inhibitors.
Topics: Allosteric Regulation; Antiviral Agents; Deoxycytidine; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Gene Expression; Hep G2 Cells; Hepatitis B virus; Humans; Isoquinolines; Kinetics; Lamivudine; Ribonuclease H; Tetrazolium Salts; Thiazoles; Tropolone; Viral Proteins; Virus Replication | 2017 |
Design, synthesis, and biologic evaluation of novel galloyl derivatives as HIV-1 RNase H inhibitors.
Topics: Anti-HIV Agents; Benzoic Acid; Binding Sites; Catalytic Domain; Drug Design; HIV-1; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Ribonuclease H, Human Immunodeficiency Virus; Structure-Activity Relationship; Tropolone | 2019 |
Novel RNase H Inhibitors Blocking RNA-directed Strand Displacement DNA Synthesis by HIV-1 Reverse Transcriptase.
Topics: Anti-Retroviral Agents; DNA, Viral; Drug Development; HIV Reverse Transcriptase; Humans; Reverse Transcriptase Inhibitors; Ribonuclease H, Human Immunodeficiency Virus; Tropolone | 2022 |