Page last updated: 2024-08-21

tropolone and 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone

tropolone has been researched along with 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199011 (40.74)18.7374
1990's10 (37.04)18.2507
2000's4 (14.81)29.6817
2010's1 (3.70)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Casal Jimenez, J; Gonzalez, C; Ripoll, P; Sunkel, CE1
Hamel, E; Hesson, DP; Jiang, JB; Kang, GJ; Lin, CM; Luduena, RF; Roach, MC1
Busson, S; Gorbunoff, MJ; Herman, G; Mauduit, P; Rossignol, B; Timasheff, SN1
Andreu, JM; Mollinedo, F; Nieto, JM1
Andreu, JM; Laynez, J; Medrano, FJ; Menéndez, M1
Hamel, E; Ho, HH; Lin, CM; Pettit, GR1
Bhattacharyya, B; Biswas, BB; Ghosh Choudhury, G; Maity, S1
Engelborghs, Y; Fitzgerald, TJ2
Andreu, JM; Avila, J; Díez, JC; Nieto, JM1
Lee, JC; Link, J; Rossi, M1
Bane, S; Macdonald, TL; Puett, D; Williams, RC1
Bhattacharyya, B; Biswas, BB; Ray, K1
Andreu, JM; Billger, M; de Pereda, JM; Wallin, M1
Bhattacharyya, B; Sackett, DL; Wolff, J1
Andreu, JM; Dumortier, C; Engelborghs, Y; Gorbunoff, MJ1
Banerjee, A1
Banerjee, A; D'Hoore, A; Engelborghs, Y; Fitzgerald, TJ1
Bane, S; Dumortier, C; Engelborghs, Y; Potenziano, JL1
Chaudhuri, AR; Ludueña, RF; Mizuhashi, F; Murata, K; Potenziano, JL; Tomita, I1
Bayley, PM; Brune, M; Martin, SR; Vandecandelaere, A; Webb, MR1
Basusarkar, P; Bhattacharyya, B; Bhattacharyya, S; Manna, T; Roy, S; Roychowdhury, M; Sarkar, N; Sarkar, T1
Chaudhuri, AR; Hausheer, FH; Ludueña, RF; Schwarz, PM; Seetharamalu, P1
Bader, V; Lübbert, H; Schmitz, B; Schoenebeck, B; Stichel, CC; Zhu, XR1
Berridge, MV; Herst, PM; Lawen, A1
Faridbod, F; Ganjali, MR; Hosseini, M; Jamali, A; Norouzi, P1
Agar, A; Aytac, G; Ozkan, A; Tanriover, G; Yildirim, S1

Reviews

1 review(s) available for tropolone and 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone

ArticleYear
Targeting mitochondrial permeability in cancer drug development.
    Molecular nutrition & food research, 2009, Volume: 53, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Energy Metabolism; Humans; Mitochondria; Mitochondrial Membranes; Neoplasms; Permeability; Tropolone

2009

Other Studies

26 other study(ies) available for tropolone and 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone

ArticleYear
The spindle is required for the process of sister chromatid separation in Drosophila neuroblasts.
    Experimental cell research, 1991, Volume: 192, Issue:1

    Topics: Animals; Chromatids; Colchicine; Drosophila melanogaster; Ganglia; Heterochromatin; Metaphase; Microtubules; Mitosis; Spindle Apparatus; Tropolone

1991
Investigation of the mechanism of the interaction of tubulin with derivatives of 2-styrylquinazolin-4(3H)-one.
    Molecular pharmacology, 1991, Volume: 40, Issue:5

    Topics: Antineoplastic Agents; Binding Sites; Colchicine; Guanosine Triphosphate; Quinazolines; Styrenes; Tropolone; Tubulin

1991
Colchicine analogues that bind reversibly to tubulin define microtubular requirements for newly synthesized protein secretion in rat lacrimal gland.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:12

    Topics: Animals; Biphenyl Compounds; Colchicine; Cycloheptanes; Fluorescent Antibody Technique; Kinetics; Lacrimal Apparatus; Male; Microtubules; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Tropolone; Tubulin

1989
Cytoplasmic microtubules in human neutrophil degranulation: reversible inhibition by the colchicine analogue 2-methoxy-5-(2',3',4'-trimethoxyphenyl)-2,4,6-cycloheptatrien-1- one.
    Molecular pharmacology, 1989, Volume: 36, Issue:4

    Topics: Cell Degranulation; Colchicine; Cycloheptanes; Cytochalasin B; Cytoplasmic Granules; Exocytosis; Fluorescent Antibody Technique; Humans; In Vitro Techniques; Microtubules; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Time Factors; Tropolone

1989
A thermodynamic study of the interaction of tubulin with colchicine site ligands.
    The Journal of biological chemistry, 1989, Oct-05, Volume: 264, Issue:28

    Topics: Animals; Binding Sites; Brain; Calorimetry; Cattle; Colchicine; Kinetics; Ligands; Protein Binding; Thermodynamics; Tropolone; Tubulin

1989
Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin.
    Biochemistry, 1989, Aug-22, Volume: 28, Issue:17

    Topics: Animals; Bibenzyls; Binding Sites; Brain; Cattle; Colchicine; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Mitosis; Models, Structural; Plant Extracts; Podophyllotoxin; Protein Binding; Stilbenes; Tropolone; Tubulin

1989
B-ring of colchicine and its role in taxol-induced tubulin polymerization.
    FEBS letters, 1986, Mar-03, Volume: 197, Issue:1-2

    Topics: Alkaloids; Animals; Brain Chemistry; Chemical Phenomena; Chemistry; Colchicine; Goats; Macromolecular Substances; Paclitaxel; Spectrometry, Fluorescence; Structure-Activity Relationship; Tropolone; Tubulin

1986
Kinetic and thermodynamic aspects of tubulin-ligand interactions: binding of the colchicine analog 2-methoxy-5-(2',3',4'-trimethoxyphenyl) tropone.
    Annals of the New York Academy of Sciences, 1986, Volume: 466

    Topics: Animals; Brain; Colchicine; Cycloheptanes; Kinetics; Ligands; Microtubules; Protein Binding; Swine; Thermodynamics; Tropolone; Tubulin

1986
A fluorescence stopped flow study of the competition and displacement kinetics of podophyllotoxin and the colchicine analog 2-methoxy-5-(2',3',4'-trimethoxyphenyl) tropone on tubulin.
    The Journal of biological chemistry, 1987, Apr-15, Volume: 262, Issue:11

    Topics: Animals; Binding, Competitive; Cycloheptanes; Dose-Response Relationship, Drug; Fluorescence; Fluorescent Dyes; Kinetics; Mathematics; Podophyllotoxin; Swine; Tropolone; Tubulin

1987
Reversible inhibition of microtubules and cell growth by the bicyclic colchicine analogue MTC.
    Cell motility and the cytoskeleton, 1987, Volume: 7, Issue:2

    Topics: Animals; Cell Division; Cell Line; Cells, Cultured; Colchicine; Cycloheptanes; Microtubules; Mitotic Index; Tropolone

1987
The structure of 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone, an effective analog of colchicine.
    Archives of biochemistry and biophysics, 1984, Volume: 231, Issue:2

    Topics: Chemical Phenomena; Chemistry; Colchicine; Computers; Cycloheptanes; Models, Molecular; Structure-Activity Relationship; Tropolone; X-Ray Diffraction

1984
Binding to tubulin of the colchicine analog 2-methoxy-5-(2', 3', 4'-trimethoxyphenyl)tropone. Thermodynamic and kinetic aspects.
    The Journal of biological chemistry, 1984, Jun-25, Volume: 259, Issue:12

    Topics: Animals; Cattle; Cycloheptanes; Fluorescence; Kinetics; Mathematics; Temperature; Thermodynamics; Tropolone; Tubulin

1984
Role of B-ring of colchicine in its binding to tubulin.
    The Journal of biological chemistry, 1981, Jun-25, Volume: 256, Issue:12

    Topics: Animals; Chemical Phenomena; Chemistry; Colchicine; Demecolcine; Goats; Kinetics; Protein Binding; Structure-Activity Relationship; Tropolone; Tubulin

1981
Comparative study of the colchicine binding site and the assembly of fish and mammalian microtubule proteins.
    Cell motility and the cytoskeleton, 1995, Volume: 30, Issue:2

    Topics: Animals; Binding Sites; Cattle; Colchicine; Fishes; Microtubule Proteins; Species Specificity; Tropolone

1995
Local unfolding and the stepwise loss of the functional properties of tubulin.
    Biochemistry, 1994, Nov-01, Volume: 33, Issue:43

    Topics: Anilino Naphthalenesulfonates; Animals; Brain Chemistry; Chymotrypsin; Colchicine; Fluorescent Dyes; GTP Phosphohydrolases; Kinetics; Microtubules; Polymers; Protein Folding; Rats; Spectrometry, Fluorescence; Tropolone; Trypsin; Tryptophan; Tubulin; Urea

1994
Alterations of rings B and C of colchicine are cumulative in overall binding to tubulin but modify each kinetic step.
    Biochemistry, 1996, Dec-10, Volume: 35, Issue:49

    Topics: Biphenyl Compounds; Colchicine; Dimerization; Fluorescence; Kinetics; Models, Chemical; Molecular Structure; Podophyllotoxin; Protein Binding; Thermodynamics; Tropolone; Tubulin

1996
Differential effects of colchicine and its B-ring modified analog MTPT on the assembly-independent GTPase activity of purified beta-tubulin isoforms from bovine brain.
    Biochemical and biophysical research communications, 1997, Feb-24, Volume: 231, Issue:3

    Topics: Animals; Brain Chemistry; Cattle; Colchicine; GTP Phosphohydrolases; Tropolone; Tubulin; Tubulin Modulators

1997
Interactions of a bicyclic analog of colchicine with beta-tubulin isoforms alphabeta(II), alphabeta(III) and alphabeta(IV).
    European journal of biochemistry, 1997, Jun-01, Volume: 246, Issue:2

    Topics: Colchicine; Dimerization; Isomerism; Kinetics; Tropolone; Tubulin

1997
The mechanism of tubulin-colchicine recognition--a kinetic study of the binding of a bicyclic colchicine analogue with a minor modification of the A ring.
    European journal of biochemistry, 1997, Oct-01, Volume: 249, Issue:1

    Topics: Animals; Anisoles; Binding Sites; Binding, Competitive; Colchicine; Cycloheptanes; In Vitro Techniques; Kinetics; Ligands; Molecular Structure; Protein Binding; Swine; Thermodynamics; Tropolone; Tubulin

1997
IKP104-induced decay of tubulin: role of the A-ring binding site of colchicine.
    Biochemistry, 1998, Dec-08, Volume: 37, Issue:49

    Topics: Alkylation; Animals; Benzaldehydes; Binding Sites; Cattle; Colchicine; Protein Conformation; Pyridones; Spectrometry, Fluorescence; Tropolone; Tubulin; Tubulin Modulators

1998
Phosphate release during microtubule assembly: what stabilizes growing microtubules?
    Biochemistry, 1999, Jun-22, Volume: 38, Issue:25

    Topics: Animals; Brain; Carrier Proteins; Coumarins; Fluorescent Dyes; GTP Phosphohydrolases; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Microtubules; Phosphate-Binding Proteins; Phosphates; Podophyllotoxin; Swine; Tropolone; Tubulin; Tubulin Modulators

1999
Sulfhydryls of tubulin. A probe to detect conformational changes of tubulin.
    European journal of biochemistry, 2000, Volume: 267, Issue:12

    Topics: Anilino Naphthalenesulfonates; Animals; Colchicine; Cysteine; Dithionitrobenzoic Acid; Protein Conformation; Rabbits; Sulfhydryl Compounds; Sulfhydryl Reagents; Time Factors; Tropolone; Tubulin

2000
The interaction of the B-ring of colchicine with alpha-tubulin: a novel footprinting approach.
    Journal of molecular biology, 2000, Nov-10, Volume: 303, Issue:5

    Topics: Amino Acid Sequence; Animals; Bibenzyls; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Colchicine; Fluorescence; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Podophyllotoxin; Protein Conformation; Protein Footprinting; Stilbenes; Tropolone; Tryptophan; Tubulin; Urea

2000
Sgk1, a cell survival response in neurodegenerative diseases.
    Molecular and cellular neurosciences, 2005, Volume: 30, Issue:2

    Topics: Animals; Cell Death; Cell Survival; Exons; Humans; Immediate-Early Proteins; Mice; Mice, Knockout; Mice, Transgenic; Motor Neuron Disease; Neurodegenerative Diseases; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; RNA, Messenger; Tropolone; Ubiquitin-Protein Ligases

2005
A Novel Cobalt-Sensitive Fluorescent Chemosensor Based on Ligand Capped CdS Quantum Dots.
    Journal of fluorescence, 2015, Volume: 25, Issue:3

    Topics: Biosensing Techniques; Cadmium Compounds; Cobalt; Copper; Fluorescence; Fluorescent Dyes; Ligands; Nanotechnology; Quantum Dots; Spectrometry, Fluorescence; Sulfides; Tropolone; Tubulin Modulators

2015
Role of melatonin in TLR4-mediated inflammatory pathway in the MTPT-induced mouse model.
    Neurotoxicology, 2022, Volume: 88

    Topics: Animals; Male; Melatonin; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Parkinsonian Disorders; Toll-Like Receptor 4; Tropolone

2022