tropisetron and tryptamine

tropisetron has been researched along with tryptamine* in 2 studies

Other Studies

2 other study(ies) available for tropisetron and tryptamine

ArticleYear
Inhibitory effects of tryptamine on tolbutamide-induced hypoglycemia in mice: mediation by 5-HT receptors.
    Neurochemical research, 1994, Volume: 19, Issue:1

    Effects of tryptamine on tolbutamide-induced hypoglycemia were investigated in mice. Tryptamine significantly inhibited hypoglycemia elicited by tolbutamide. The inhibitory effects of tryptamine were strongly blocked by the 5-HT1 and 5-HT2 receptor antagonist methysergide and the 5-HT2 receptor antagonist ketanserin, while the 5-HT3 receptor antagonist ICS 205-930 was without effect. Tryptamine induced hyperglucagonemia in tolbutamide-treated mice, and this effect elicited by tryptamine was strongly inhibited by the 5-HT2 receptor antagonist ketanserin. These results suggest that the inhibitory effects of tryptamine on tolbutamide-induced hypoglycemia are mediated by 5-HT2 receptors and that tryptamine is involved in glucagon release.

    Topics: Animals; Blood Glucose; Hypoglycemia; Indoles; Ketanserin; Male; Methysergide; Mice; Mice, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Time Factors; Tolbutamide; Tropisetron; Tryptamines

1994
The activation of serotonin receptors by tryptamine induces hyperinsulinemia in mice.
    European journal of pharmacology, 1990, Jun-08, Volume: 181, Issue:3

    The effects of tryptamine on serum insulin levels were investigated. Tryptamine induced an apparent increase in serum insulin levels in mice. The elevation in insulin elicited by tryptamine was potently antagonized by the 5-HT1 and 5-HT2 receptor antagonist, methysergide, but partially reduced by the 5-HT2 receptor antagonist, ketanserin. However, the 5-HT3 receptor antagonist, ICS 205-930, was without effect. These results indicate that both 5-HT1 and 5-HT2 receptors are involved in the tryptamine-induced increase in insulin levels.

    Topics: Animals; Indoles; Insulin; Male; Mice; Mice, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tropisetron; Tryptamines

1990
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