troleandomycin has been researched along with troglitazone in 5 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (troglitazone) | Trials (troglitazone) | Recent Studies (post-2010) (troglitazone) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 1,857 | 146 | 287 |
| Protein | Taxonomy | troleandomycin (IC50) | troglitazone (IC50) |
|---|---|---|---|
| Bile salt export pump | Rattus norvegicus (Norway rat) | 3.9 | |
| Bile salt export pump | Homo sapiens (human) | 5.05 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 0.97 | |
| Adenosine receptor A3 | Homo sapiens (human) | 5.208 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 4 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.208 | |
| Thromboxane-A synthase | Homo sapiens (human) | 2.966 | |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | 2.07 | |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | 1.238 | |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | 1.03 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.312 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.208 | |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | 1.285 | |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | 1.285 | |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | 4.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T | 1 |
5 other study(ies) available for troleandomycin and troglitazone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin | 2005 |