troleandomycin has been researched along with proadifen in 7 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (proadifen) | Trials (proadifen) | Recent Studies (post-2010) (proadifen) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 1,481 | 0 | 35 |
| Protein | Taxonomy | troleandomycin (IC50) | proadifen (IC50) |
|---|---|---|---|
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.5849 | |
| Aldehyde oxidase 1 | Rattus norvegicus (Norway rat) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiu, SH; Karanam, BV; Painter, SK; Vincent, SH | 1 |
| Franklin, MR; Pershing, LK | 1 |
| Kupfer, D; Mani, C; Parkinson, A; Pearce, R | 1 |
| Juvonen, RO; Kojo, A; Komulainen, H; Liesivuori, J; Pasanen, M; Pennanen, S | 1 |
| Ariyama, J; Furuno, H; Hirai, K; Koyama, J; Shimada, H; Simamura, E | 1 |
| Choi, YH; Lee, JH; Lee, MG; Lee, U; Yang, KH | 1 |
| Kubickova, B; Martinkova, M; Stiborova, M | 1 |
7 other study(ies) available for troleandomycin and proadifen
| Article | Year |
|---|---|
In vitro metabolism of FK-506 in rat, rabbit, and human liver microsomes: identification of a major metabolite and of cytochrome P450 3A as the major enzymes responsible for its metabolism.
Topics: Adult; Animals; Antibodies; Biotransformation; Carbon Radioisotopes; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; Female; Humans; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Proadifen; Rabbits; Rats; Rats, Inbred Strains; Tacrolimus; Troleandomycin | 1992 |
Cytochrome P-450 metabolic-intermediate complex formation and induction by macrolide antibiotics; a new class of agents.
Topics: Animals; Anti-Bacterial Agents; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Proadifen; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Troleandomycin | 1982 |
Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzimidazoles; Biotransformation; Chickens; Cricetinae; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Female; Humans; Hydrocortisone; Immunoglobulin G; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Protein Binding; Rats; Rats, Sprague-Dawley; Species Specificity; Tamoxifen; Troleandomycin | 1994 |
CYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver.
Topics: Aged; Animals; Antibodies, Monoclonal; Caproates; Cytochrome P-450 Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; Isoenzymes; Male; Methylation; Metyrapone; Mice; Microsomes, Liver; Middle Aged; NADPH-Ferrihemoprotein Reductase; Occupational Exposure; Proadifen; Quinidine; Rats; Rats, Wistar; Troleandomycin | 1996 |
Paraquat detoxicative system in the mouse liver postmitochondrial fraction.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cobalt; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred ICR; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Paraquat; Phenobarbital; Phenytoin; Proadifen; Rabbits; Rifampin; Troleandomycin; Vitamin E | 2002 |
Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism.
Topics: Animals; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cimetidine; Cytochrome P-450 Enzyme System; Diuretics; Drug Interactions; Enzyme Activators; Enzyme Inhibitors; Furosemide; Half-Life; Infusions, Intravenous; Injections, Intravenous; Isoniazid; Male; Methylcholanthrene; Orphenadrine; Proadifen; Quinine; Rats; Rats, Sprague-Dawley; Troleandomycin; Weight Gain | 2009 |
Effects of cytochrome P450 inhibitors on peroxidase activity.
Topics: Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Ellipticines; Enzyme Activation; Enzyme Inhibitors; Horseradish Peroxidase; Humans; Ketoconazole; Metyrapone; Piperonyl Butoxide; Proadifen; Quinidine; Structure-Activity Relationship; Substrate Specificity; Sulfaphenazole; Triazoles; Troleandomycin | 2012 |