Page last updated: 2024-09-05

troleandomycin and primaquine

troleandomycin has been researched along with primaquine in 3 studies

Compound Research Comparison

Studies
(troleandomycin)
Trials
(troleandomycin)
Recent Studies (post-2010)
(troleandomycin)
Studies
(primaquine)
Trials
(primaquine)
Recent Studies (post-2010) (primaquine)
56926232,196196711

Protein Interaction Comparison

ProteinTaxonomytroleandomycin (IC50)primaquine (IC50)
Cytochrome P450 1A2Homo sapiens (human)0.1824
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)7.5
Sodium-dependent serotonin transporterHomo sapiens (human)0.016
Serine hydroxymethyltransferase, mitochondrialHomo sapiens (human)0.4365
Thiosulfate sulfurtransferaseHomo sapiens (human)2.9
60 kDa chaperonin Escherichia coli6.2
10 kDa chaperonin Escherichia coli6.2

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ishizaki, T; Zhao, XJ1
Ganesan, S; Sahu, R; Tekwani, BL; Tripathi, LM; Walker, LA1

Other Studies

3 other study(ies) available for troleandomycin and primaquine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Metabolic interactions of selected antimalarial and non-antimalarial drugs with the major pathway (3-hydroxylation) of quinine in human liver microsomes.
    British journal of clinical pharmacology, 1997, Volume: 44, Issue:5

    Topics: Anti-Infective Agents; Antimalarials; Chromatography; Cytochrome P-450 Enzyme System; Doxycycline; Drug Interactions; Erythromycin; Humans; Hydroxylation; Ketoconazole; Microsomes, Liver; Nifedipine; Omeprazole; Primaquine; Quinine; Tetracycline; Troleandomycin

1997
Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.
    Toxicology and applied pharmacology, 2009, Nov-15, Volume: 241, Issue:1

    Topics: Animals; Antimalarials; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Erythrocytes; Female; Fluoxetine; Glucosephosphate Dehydrogenase; Humans; Isoenzymes; Male; Methemoglobin; Mice; Mice, Inbred ICR; Microsomes, Liver; Oxidative Stress; Primaquine; Reactive Oxygen Species; Sulfhydryl Compounds; Thiotepa; Troleandomycin

2009