Page last updated: 2024-09-05

troleandomycin and perhexiline

troleandomycin has been researched along with perhexiline in 3 studies

Compound Research Comparison

Studies
(troleandomycin)
Trials
(troleandomycin)
Recent Studies (post-2010)
(troleandomycin)
Studies
(perhexiline)
Trials
(perhexiline)
Recent Studies (post-2010) (perhexiline)
56926235729283

Protein Interaction Comparison

ProteinTaxonomytroleandomycin (IC50)perhexiline (IC50)
Epidermal growth factor receptorHomo sapiens (human)1.4852
Tyrosine-protein kinase FynHomo sapiens (human)4.064
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.2942
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.5919
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.0932
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 26.38
Cytochrome P450 2D6Homo sapiens (human)0.9408
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.7105
DRattus norvegicus (Norway rat)7.7625
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)7.7625
Muscarinic acetylcholine receptor M3Homo sapiens (human)3.1186
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)7.7625
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)7.7625
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.2942
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)7.7625
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)7.7687
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.5992

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1

Other Studies

3 other study(ies) available for troleandomycin and perhexiline

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012