troleandomycin has been researched along with paclitaxel in 10 studies
| Studies (troleandomycin) | Trials (troleandomycin) | Recent Studies (post-2010) (troleandomycin) | Studies (paclitaxel) | Trials (paclitaxel) | Recent Studies (post-2010) (paclitaxel) |
|---|---|---|---|---|---|
| 569 | 26 | 23 | 31,874 | 5,729 | 15,395 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Collins, JM; Guengerich, FP; Harris, JW; Kim, BR; Rahman, A | 1 |
| Gonzalez, FJ; Grogan, J; Harris, JW; Korzekwa, KR; Rahman, A | 1 |
| Kostrubsky, VE; Lewis, LD; Sinclair, JF; Sinclair, PR; Wood, SG; Wrighton, SA | 1 |
| Anzenbacher, P; Guengerich, FP; Gut, I; Simek, P; Soucek, P; Svobodova, L; Vaclavikova, R | 1 |
| Marks, B; Raucy, J; Trubetskoy, O; Yueh, MF; Zielinski, T | 1 |
10 other study(ies) available for troleandomycin and paclitaxel
| Article | Year |
|---|---|
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors | 2001 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Metabolism of taxol by human hepatic microsomes and liver slices: participation of cytochrome P450 3A4 and an unknown P450 enzyme.
Topics: Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases; Paclitaxel; Taxoids; Troleandomycin | 1994 |
Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8.
Topics: Biotransformation; Cytochrome P-450 Enzyme System; Humans; Hydroxylation; Microsomes, Liver; Paclitaxel; Quercetin; Taxoids; Troleandomycin | 1994 |
Effect of Taxol on cytochrome P450 3A and acetaminophen toxicity in cultured rat hepatocytes: comparison to dexamethasone.
Topics: Acetaminophen; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Synergism; Enzyme Induction; Enzyme Inhibitors; Liver; Male; Oxidoreductases, N-Demethylating; Paclitaxel; Rats; Rats, Inbred F344; RNA, Messenger; Troleandomycin | 1997 |
Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs.
Topics: Adolescent; Adult; Animals; Antineoplastic Agents, Phytogenic; Cytochrome P-450 Enzyme System; Docetaxel; Enzyme Inhibitors; Flavonoids; Flavonols; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Male; Microsomes, Liver; Paclitaxel; Rats; Rats, Wistar; Species Specificity; Swine; Swine, Miniature; Taxoids; Troleandomycin | 2004 |
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Chromans; Clotrimazole; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enhancer Elements, Genetic; Enzyme Induction; Genes, Reporter; Genes, Synthetic; Humans; Ketoconazole; Liver Neoplasms; Lovastatin; Luciferases; Mifepristone; Neoplasm Proteins; Nifedipine; Omeprazole; Paclitaxel; Phenytoin; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Rifampin; Thiazolidinediones; Transcription, Genetic; Troglitazone; Troleandomycin | 2005 |